Overview

ID MAG01720
Name HKD1_bin.38
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 88.27
Contamination (%) 7.36
GC content (%) 53.0
N50 (bp) 11,999
Genome size (bp) 2,838,811

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2758

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1012828_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.27e-206 660.0
HKD1_k127_1012828_1 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 469.0
HKD1_k127_1012828_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
HKD1_k127_103509_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 575.0
HKD1_k127_103509_1 S-methyl-5-thioadenosine phosphorylase activity K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
HKD1_k127_103509_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 285.0
HKD1_k127_103509_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000001368 166.0
HKD1_k127_103509_4 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000008353 136.0
HKD1_k127_103509_5 Predicted membrane protein (DUF2207) - - - 0.0000000001914 63.0
HKD1_k127_103509_6 Aspartyl protease - - - 0.000006315 55.0
HKD1_k127_103654_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 386.0
HKD1_k127_103654_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 386.0
HKD1_k127_103654_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000001942 182.0
HKD1_k127_103654_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000002743 161.0
HKD1_k127_103654_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000575 90.0
HKD1_k127_1036782_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 399.0
HKD1_k127_1036782_1 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
HKD1_k127_1040036_0 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 584.0
HKD1_k127_1040036_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 453.0
HKD1_k127_1040036_2 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HKD1_k127_1040036_3 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.00000000000000000000001334 100.0
HKD1_k127_104310_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 550.0
HKD1_k127_104310_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 358.0
HKD1_k127_104310_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
HKD1_k127_104310_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000031 278.0
HKD1_k127_104310_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000002528 201.0
HKD1_k127_104310_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000005946 183.0
HKD1_k127_104310_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000003396 132.0
HKD1_k127_104310_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000003135 73.0
HKD1_k127_1056421_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 569.0
HKD1_k127_1056421_1 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 516.0
HKD1_k127_1056421_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 478.0
HKD1_k127_1056421_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 329.0
HKD1_k127_1056421_4 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
HKD1_k127_1056421_5 Histidine kinase K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000004148 187.0
HKD1_k127_1056421_6 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000002923 153.0
HKD1_k127_1056421_7 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000004414 114.0
HKD1_k127_1057376_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 408.0
HKD1_k127_1057376_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 331.0
HKD1_k127_1057376_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
HKD1_k127_1057376_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000002005 166.0
HKD1_k127_1057376_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000001609 159.0
HKD1_k127_1057376_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001527 128.0
HKD1_k127_1057376_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001213 102.0
HKD1_k127_1057376_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000008526 83.0
HKD1_k127_1076783_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.029e-260 817.0
HKD1_k127_1076783_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 466.0
HKD1_k127_1076783_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 291.0
HKD1_k127_1076783_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001805 256.0
HKD1_k127_1076783_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000009192 228.0
HKD1_k127_1076783_5 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000002206 229.0
HKD1_k127_1076783_6 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000001218 179.0
HKD1_k127_1076783_7 Domain of Unknown Function (DUF748) - - - 0.00000000002922 67.0
HKD1_k127_1094065_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.503e-269 843.0
HKD1_k127_1094065_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 553.0
HKD1_k127_1094065_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000477 95.0
HKD1_k127_1094065_11 PhoH-like protein K06217 - - 0.0000002114 52.0
HKD1_k127_1094065_2 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 485.0
HKD1_k127_1094065_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 402.0
HKD1_k127_1094065_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 399.0
HKD1_k127_1094065_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 344.0
HKD1_k127_1094065_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001076 256.0
HKD1_k127_1094065_7 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000004676 214.0
HKD1_k127_1094065_8 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000000000000000000002547 178.0
HKD1_k127_1094065_9 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000001087 139.0
HKD1_k127_1096741_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 3.235e-283 873.0
HKD1_k127_1096741_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000024 250.0
HKD1_k127_1096741_2 Histidine kinase K02660,K07315 - 3.1.3.3 0.00000000000002978 73.0
HKD1_k127_1096741_3 Belongs to the catalase family K03781 - 1.11.1.6 0.00000000004359 64.0
HKD1_k127_1100309_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.841e-296 917.0
HKD1_k127_1100309_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 369.0
HKD1_k127_1100309_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 341.0
HKD1_k127_1100309_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 313.0
HKD1_k127_1100309_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 308.0
HKD1_k127_1100309_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002029 215.0
HKD1_k127_1100309_6 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000005591 95.0
HKD1_k127_1100309_7 iron-regulated protein - - - 0.0000000000001725 72.0
HKD1_k127_1100309_8 Sporulation and spore germination - - - 0.00000000004596 70.0
HKD1_k127_1106490_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2138.0
HKD1_k127_1106490_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1615.0
HKD1_k127_1106490_10 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000004515 145.0
HKD1_k127_1106490_11 response regulator, receiver - - - 0.000000000000000000000000000000000276 139.0
HKD1_k127_1106490_12 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000000009484 114.0
HKD1_k127_1106490_13 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000005475 92.0
HKD1_k127_1106490_14 transcription factor binding - - - 0.0000000000000000003789 95.0
HKD1_k127_1106490_15 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00003901 51.0
HKD1_k127_1106490_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.445e-218 683.0
HKD1_k127_1106490_3 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 473.0
HKD1_k127_1106490_4 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 367.0
HKD1_k127_1106490_5 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 363.0
HKD1_k127_1106490_6 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 297.0
HKD1_k127_1106490_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000829 195.0
HKD1_k127_1106490_8 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000003382 147.0
HKD1_k127_1106490_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000001252 149.0
HKD1_k127_1125667_0 Sensory domain found in PocR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 325.0
HKD1_k127_1125667_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 286.0
HKD1_k127_1125679_0 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 279.0
HKD1_k127_1125679_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000001616 215.0
HKD1_k127_1125679_2 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000009668 172.0
HKD1_k127_1125679_3 STAS domain K04749 - - 0.00000000000000000000002845 102.0
HKD1_k127_1125679_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000004408 80.0
HKD1_k127_1139101_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 8.974e-279 864.0
HKD1_k127_1139101_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.196e-202 638.0
HKD1_k127_1139101_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 580.0
HKD1_k127_1139101_3 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000005018 169.0
HKD1_k127_1139101_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000006324 136.0
HKD1_k127_1139101_5 - - - - 0.0000000001118 71.0
HKD1_k127_1140091_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 596.0
HKD1_k127_1140091_1 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 504.0
HKD1_k127_1140091_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 428.0
HKD1_k127_1140091_3 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 277.0
HKD1_k127_1140091_4 Cell division response regulator DivK K11443 - - 0.00000000000000000001761 95.0
HKD1_k127_1158390_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 576.0
HKD1_k127_1158390_1 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
HKD1_k127_1158390_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000004471 190.0
HKD1_k127_1158390_3 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000001588 170.0
HKD1_k127_1158390_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000001204 153.0
HKD1_k127_1158390_5 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000002571 119.0
HKD1_k127_1158390_6 membrane - - - 0.0000000000000000000819 94.0
HKD1_k127_1170566_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.315e-265 830.0
HKD1_k127_1170566_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 417.0
HKD1_k127_1170566_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 355.0
HKD1_k127_1170566_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000001094 68.0
HKD1_k127_1170566_4 ATP-independent chaperone mediated protein folding - - - 0.0000005698 59.0
HKD1_k127_1170838_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 579.0
HKD1_k127_1170838_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 578.0
HKD1_k127_1170838_10 - - - - 0.000000000000002537 82.0
HKD1_k127_1170838_2 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 492.0
HKD1_k127_1170838_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 456.0
HKD1_k127_1170838_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 362.0
HKD1_k127_1170838_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003373 273.0
HKD1_k127_1170838_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000002831 210.0
HKD1_k127_1170838_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000003508 203.0
HKD1_k127_1170838_8 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000000000000002723 155.0
HKD1_k127_1170838_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000001502 120.0
HKD1_k127_119916_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 415.0
HKD1_k127_119916_1 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000002551 185.0
HKD1_k127_119916_2 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000002592 147.0
HKD1_k127_119916_3 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000726 134.0
HKD1_k127_119916_4 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.0000000000000000000000001033 116.0
HKD1_k127_119916_5 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000002595 95.0
HKD1_k127_119916_6 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000005001 91.0
HKD1_k127_119916_7 - - - - 0.0000000000004189 71.0
HKD1_k127_119916_8 HD domain - - - 0.000000003417 68.0
HKD1_k127_122852_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 458.0
HKD1_k127_122852_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000007865 181.0
HKD1_k127_1234396_0 Predicted permease K07089 - - 3.8e-242 764.0
HKD1_k127_1234396_1 SMART Elongator protein 3 MiaB NifB K22226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 443.0
HKD1_k127_1234396_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 347.0
HKD1_k127_1234396_3 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000001135 211.0
HKD1_k127_1234396_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000006569 156.0
HKD1_k127_1234396_5 PFAM PKD domain containing protein - - - 0.00000000000000000000004942 113.0
HKD1_k127_1234396_7 peptidyl-tyrosine sulfation - - - 0.000001283 56.0
HKD1_k127_1240432_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.19e-196 620.0
HKD1_k127_1240432_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 455.0
HKD1_k127_1240432_10 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 299.0
HKD1_k127_1240432_11 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
HKD1_k127_1240432_12 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009114 273.0
HKD1_k127_1240432_13 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000002576 194.0
HKD1_k127_1240432_14 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000002071 194.0
HKD1_k127_1240432_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000002857 171.0
HKD1_k127_1240432_16 PFAM methyltransferase - - - 0.00000000000000000000000000000009631 134.0
HKD1_k127_1240432_17 oxidoreductase activity - - - 0.00000000000000001278 96.0
HKD1_k127_1240432_18 Carboxypeptidase regulatory-like domain - - - 0.000000002643 63.0
HKD1_k127_1240432_19 O-antigen ligase K02847 - - 0.0000002837 63.0
HKD1_k127_1240432_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 433.0
HKD1_k127_1240432_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 418.0
HKD1_k127_1240432_4 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 411.0
HKD1_k127_1240432_5 PFAM glycosyl transferase, family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 411.0
HKD1_k127_1240432_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 401.0
HKD1_k127_1240432_7 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 399.0
HKD1_k127_1240432_8 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 361.0
HKD1_k127_1240432_9 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 302.0
HKD1_k127_1248217_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 531.0
HKD1_k127_1248217_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 396.0
HKD1_k127_1248217_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 387.0
HKD1_k127_1273244_0 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 570.0
HKD1_k127_1273244_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 462.0
HKD1_k127_1273244_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 366.0
HKD1_k127_1273244_3 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
HKD1_k127_1273244_4 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000005305 53.0
HKD1_k127_1282141_0 PFAM Type II secretion system protein E K02454 - - 3.723e-198 629.0
HKD1_k127_1282141_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 555.0
HKD1_k127_1282141_10 Prokaryotic N-terminal methylation motif K02458 - - 0.00000001733 60.0
HKD1_k127_1282141_2 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 548.0
HKD1_k127_1282141_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 489.0
HKD1_k127_1282141_4 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 295.0
HKD1_k127_1282141_5 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000002767 211.0
HKD1_k127_1282141_6 SMART PDZ DHR GLGF domain protein K02452 - - 0.000000000000000000000000000000000000001466 158.0
HKD1_k127_1282141_7 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000002074 117.0
HKD1_k127_1282141_8 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000009171 85.0
HKD1_k127_1282141_9 Type II secretion system (T2SS), protein K K02460 - - 0.0000000004163 70.0
HKD1_k127_1283424_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.198e-204 642.0
HKD1_k127_1283424_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 546.0
HKD1_k127_1283424_10 reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003232 276.0
HKD1_k127_1283424_11 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005322 276.0
HKD1_k127_1283424_12 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009006 270.0
HKD1_k127_1283424_13 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HKD1_k127_1283424_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000001456 222.0
HKD1_k127_1283424_15 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000000000000000000002831 210.0
HKD1_k127_1283424_16 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000002008 210.0
HKD1_k127_1283424_17 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000005422 208.0
HKD1_k127_1283424_18 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000005797 214.0
HKD1_k127_1283424_19 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000005698 209.0
HKD1_k127_1283424_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 516.0
HKD1_k127_1283424_20 Universal stress protein family K07090 - - 0.00000000000000000000000000000000000000000000000000005531 197.0
HKD1_k127_1283424_22 - - - - 0.000000000000000000000000000000000000000002234 165.0
HKD1_k127_1283424_23 - - - - 0.00000000000000000000000000000000000001248 151.0
HKD1_k127_1283424_24 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000009556 104.0
HKD1_k127_1283424_25 - - - - 0.0000000000000000414 88.0
HKD1_k127_1283424_26 Ami_2 - - - 0.0000000000000005259 92.0
HKD1_k127_1283424_28 - - - - 0.00000000003504 70.0
HKD1_k127_1283424_29 His Kinase A (phosphoacceptor) domain - - - 0.000000001551 61.0
HKD1_k127_1283424_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
HKD1_k127_1283424_31 leucine- rich repeat protein - - - 0.000000006986 69.0
HKD1_k127_1283424_32 His Kinase A (phosphoacceptor) domain - - - 0.00003714 49.0
HKD1_k127_1283424_33 Protein of unknown function DUF116 K09729 - - 0.00009042 53.0
HKD1_k127_1283424_34 ABC transporter substrate-binding protein - - - 0.000108 48.0
HKD1_k127_1283424_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 494.0
HKD1_k127_1283424_5 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 483.0
HKD1_k127_1283424_6 helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 447.0
HKD1_k127_1283424_7 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 380.0
HKD1_k127_1283424_8 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 364.0
HKD1_k127_1283424_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 352.0
HKD1_k127_1283928_0 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 405.0
HKD1_k127_1283928_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 339.0
HKD1_k127_1283928_2 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000004145 213.0
HKD1_k127_1283928_3 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000002609 174.0
HKD1_k127_1283928_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000007909 110.0
HKD1_k127_1283928_5 rRNA binding K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000004197 79.0
HKD1_k127_1287226_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
HKD1_k127_1287226_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000002466 150.0
HKD1_k127_1287226_2 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000003014 134.0
HKD1_k127_1287226_4 Protein of unknown function (DUF1573) - - - 0.00003926 48.0
HKD1_k127_1288232_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 6.272e-229 727.0
HKD1_k127_1288232_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 5.855e-220 688.0
HKD1_k127_1288232_10 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000001847 137.0
HKD1_k127_1288232_11 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000001221 129.0
HKD1_k127_1288232_12 NIL - - - 0.0000000000000000000000000000001959 125.0
HKD1_k127_1288232_13 - - - - 0.000000000000000000000000001443 115.0
HKD1_k127_1288232_14 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000006799 94.0
HKD1_k127_1288232_15 - - - - 0.00000000000004793 71.0
HKD1_k127_1288232_16 Belongs to the peptidase M16 family K07263 - - 0.000134 47.0
HKD1_k127_1288232_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 596.0
HKD1_k127_1288232_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 542.0
HKD1_k127_1288232_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 535.0
HKD1_k127_1288232_5 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 361.0
HKD1_k127_1288232_6 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000005724 231.0
HKD1_k127_1288232_7 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000000001555 188.0
HKD1_k127_1288232_8 ThiS family K03636 - - 0.000000000000000000000000000000000042 136.0
HKD1_k127_1288232_9 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000004222 138.0
HKD1_k127_1293463_0 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.0 1797.0
HKD1_k127_1293463_1 Cytochrome c554 and c-prime - - - 3.208e-243 759.0
HKD1_k127_1293463_10 Acetyltransferase (GNAT) domain - - - 0.000004239 55.0
HKD1_k127_1293463_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 616.0
HKD1_k127_1293463_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 477.0
HKD1_k127_1293463_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 466.0
HKD1_k127_1293463_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
HKD1_k127_1293463_6 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000009218 211.0
HKD1_k127_1293463_7 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000001931 191.0
HKD1_k127_1293463_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000009877 184.0
HKD1_k127_1293463_9 Cold shock K03704 - - 0.000000000006691 65.0
HKD1_k127_1320689_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.85e-270 846.0
HKD1_k127_1320689_1 Belongs to the glycosyl hydrolase 57 family - - - 1.838e-254 800.0
HKD1_k127_13289_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 535.0
HKD1_k127_13289_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 467.0
HKD1_k127_13289_10 - - - - 0.000000001045 67.0
HKD1_k127_13289_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 306.0
HKD1_k127_13289_3 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000966 279.0
HKD1_k127_13289_4 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000001119 192.0
HKD1_k127_13289_5 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000000003594 166.0
HKD1_k127_13289_6 Yhs domain-containing protein - - - 0.00000000000000000000000000000000000000002287 157.0
HKD1_k127_13289_7 - - - - 0.000000000000000000000006653 108.0
HKD1_k127_13289_8 deoxyhypusine monooxygenase activity K01387 - 3.4.24.3 0.00000000000000001136 98.0
HKD1_k127_1349600_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 342.0
HKD1_k127_1349600_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 255.0
HKD1_k127_1349600_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001448 247.0
HKD1_k127_1349600_3 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000387 234.0
HKD1_k127_1349600_4 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000293 218.0
HKD1_k127_1365544_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 4.395e-239 769.0
HKD1_k127_1365544_1 Glutathionylspermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 439.0
HKD1_k127_1365544_2 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000006924 207.0
HKD1_k127_1365544_3 methyltransferase activity - - - 0.00000000000000000000000000000000000000003092 159.0
HKD1_k127_1365544_4 Membrane K08989 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004305 128.0
HKD1_k127_1365544_5 Universal stress protein family - - - 0.000000000001218 74.0
HKD1_k127_1365544_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000003648 61.0
HKD1_k127_1365544_7 Universal stress protein K06149 - - 0.0000001033 61.0
HKD1_k127_1365544_8 PFAM FAD linked oxidase domain protein - - - 0.000002057 49.0
HKD1_k127_1365544_9 - K00712 - 2.4.1.52 0.000003096 59.0
HKD1_k127_1366901_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 6.034e-244 769.0
HKD1_k127_1366901_1 GAF domain - - - 8.873e-203 676.0
HKD1_k127_1366901_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000008415 262.0
HKD1_k127_1366901_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000214 254.0
HKD1_k127_1366901_12 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000005912 250.0
HKD1_k127_1366901_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000001876 173.0
HKD1_k127_1366901_14 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000007755 168.0
HKD1_k127_1366901_15 - - - - 0.0000000000000000000000000000000000005608 145.0
HKD1_k127_1366901_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 542.0
HKD1_k127_1366901_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 460.0
HKD1_k127_1366901_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 456.0
HKD1_k127_1366901_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 428.0
HKD1_k127_1366901_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 359.0
HKD1_k127_1366901_7 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 329.0
HKD1_k127_1366901_8 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 295.0
HKD1_k127_1366901_9 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001766 265.0
HKD1_k127_1376976_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 407.0
HKD1_k127_1376976_1 Histidine kinase - - - 0.00000000351 69.0
HKD1_k127_1414140_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.192e-244 769.0
HKD1_k127_1414140_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 3.197e-233 737.0
HKD1_k127_1414140_2 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 456.0
HKD1_k127_1414140_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001913 250.0
HKD1_k127_1414140_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000002088 164.0
HKD1_k127_1414140_5 response regulator K02667 - - 0.0000000000000000000000000001886 119.0
HKD1_k127_1414140_6 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0002845 44.0
HKD1_k127_1423256_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 356.0
HKD1_k127_1423256_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000009427 222.0
HKD1_k127_1423256_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000002374 187.0
HKD1_k127_1423256_3 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000002265 178.0
HKD1_k127_1423256_4 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000001069 174.0
HKD1_k127_1444247_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.4e-267 845.0
HKD1_k127_1444247_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 490.0
HKD1_k127_1444247_10 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000001471 169.0
HKD1_k127_1444247_11 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000001322 166.0
HKD1_k127_1444247_12 PFAM Toluene tolerance K07323 - - 0.00000000000000000000000000000000000007777 150.0
HKD1_k127_1444247_13 Amidohydrolase family - - - 0.00000000000000000000000000000000002251 149.0
HKD1_k127_1444247_14 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000001176 139.0
HKD1_k127_1444247_15 Smr domain - - - 0.000000000000000000000000000004446 122.0
HKD1_k127_1444247_16 phosphorelay signal transduction system - - - 0.000000000000000000000004368 110.0
HKD1_k127_1444247_18 Belongs to the universal stress protein A family - - - 0.000000000421 66.0
HKD1_k127_1444247_2 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
HKD1_k127_1444247_3 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 436.0
HKD1_k127_1444247_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
HKD1_k127_1444247_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 361.0
HKD1_k127_1444247_6 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
HKD1_k127_1444247_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 295.0
HKD1_k127_1444247_8 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000008428 240.0
HKD1_k127_1444247_9 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001799 229.0
HKD1_k127_1454484_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1039.0
HKD1_k127_1454484_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.198e-249 792.0
HKD1_k127_1454484_10 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000002128 110.0
HKD1_k127_1454484_11 PFAM GAF domain protein - - - 0.0000000000000000000002284 112.0
HKD1_k127_1454484_12 Cysteine-rich small domain K07162 - - 0.00000000000000001433 85.0
HKD1_k127_1454484_13 Transcriptional regulator, MerR family - - - 0.000000000000000144 81.0
HKD1_k127_1454484_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.00000000000007646 72.0
HKD1_k127_1454484_16 Rhodanese domain protein - - - 0.00000001394 60.0
HKD1_k127_1454484_17 phosphorelay sensor kinase activity - - - 0.00000006907 65.0
HKD1_k127_1454484_18 - - - - 0.000001907 53.0
HKD1_k127_1454484_19 - - - - 0.000004304 54.0
HKD1_k127_1454484_2 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 501.0
HKD1_k127_1454484_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 501.0
HKD1_k127_1454484_4 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 314.0
HKD1_k127_1454484_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003762 279.0
HKD1_k127_1454484_6 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000596 226.0
HKD1_k127_1454484_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000002783 212.0
HKD1_k127_1454484_8 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000001644 132.0
HKD1_k127_1454484_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000007509 119.0
HKD1_k127_148559_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 417.0
HKD1_k127_148559_1 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000001765 168.0
HKD1_k127_148559_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000006082 149.0
HKD1_k127_148559_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000009038 57.0
HKD1_k127_148559_4 Universal stress protein family - - - 0.00001999 53.0
HKD1_k127_1493115_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002512 247.0
HKD1_k127_1493115_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000003583 145.0
HKD1_k127_1493115_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000142 121.0
HKD1_k127_1495422_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000397 141.0
HKD1_k127_1495422_1 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000009977 108.0
HKD1_k127_1495422_2 Endonuclease containing a URI domain K07461 - - 0.00000000003117 66.0
HKD1_k127_1495422_3 cellulase activity K01179 - 3.2.1.4 0.00000000003327 75.0
HKD1_k127_1495422_4 CARDB - - - 0.00011 53.0
HKD1_k127_1495423_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 441.0
HKD1_k127_1495423_1 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 437.0
HKD1_k127_1495423_2 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000003978 232.0
HKD1_k127_1495423_3 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000114 189.0
HKD1_k127_1495423_4 sulfur carrier activity K04085 - - 0.000000000000000000002753 95.0
HKD1_k127_1504654_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 5.738e-206 651.0
HKD1_k127_1504654_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 437.0
HKD1_k127_1504654_2 Lysin motif - - - 0.000000000000000000000000000000000577 145.0
HKD1_k127_1504654_3 Unextendable partial coding region - - - 0.00005936 47.0
HKD1_k127_1556092_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 1.271e-211 667.0
HKD1_k127_1556092_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 594.0
HKD1_k127_1556092_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 374.0
HKD1_k127_1556092_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002974 277.0
HKD1_k127_1556092_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 263.0
HKD1_k127_1556092_5 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000001861 132.0
HKD1_k127_1556092_6 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001249 131.0
HKD1_k127_1556092_7 NusG domain II K00805 - 2.5.1.30 0.00000000000000002409 86.0
HKD1_k127_1556092_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000002391 78.0
HKD1_k127_1571379_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 406.0
HKD1_k127_1571379_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 379.0
HKD1_k127_1571379_2 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 366.0
HKD1_k127_1571379_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000007073 166.0
HKD1_k127_1571379_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000001238 162.0
HKD1_k127_1571379_5 SpoIIAA-like - - - 0.0000000000000000000000000000000000009164 142.0
HKD1_k127_1635168_0 Surface antigen K07277 - - 7.68e-263 829.0
HKD1_k127_1635168_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 7.053e-226 711.0
HKD1_k127_1635168_10 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000008015 153.0
HKD1_k127_1635168_11 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000003687 109.0
HKD1_k127_1635168_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 392.0
HKD1_k127_1635168_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 378.0
HKD1_k127_1635168_4 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 330.0
HKD1_k127_1635168_5 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001476 271.0
HKD1_k127_1635168_6 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002106 261.0
HKD1_k127_1635168_7 PFAM metal-dependent phosphohydrolase, HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
HKD1_k127_1635168_8 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000001965 217.0
HKD1_k127_1635168_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000006287 210.0
HKD1_k127_16591_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
HKD1_k127_16591_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001177 191.0
HKD1_k127_16591_2 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000001453 171.0
HKD1_k127_16591_3 - - - - 0.00000000000000000000000000002243 121.0
HKD1_k127_16591_4 Belongs to the 'phage' integrase family - - - 0.0000003208 58.0
HKD1_k127_16591_5 Acetyltransferase - - - 0.0008714 46.0
HKD1_k127_172142_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 379.0
HKD1_k127_172142_1 Efflux ABC transporter, permease protein K02004 - - 0.000000000000000000000000001576 117.0
HKD1_k127_172142_2 UPF0761 membrane protein K07058 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000006796 73.0
HKD1_k127_172142_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000903 57.0
HKD1_k127_1760_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0 1041.0
HKD1_k127_1760_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.822e-233 728.0
HKD1_k127_1760_10 RNA polymerase activity K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000004815 72.0
HKD1_k127_1760_11 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000004625 66.0
HKD1_k127_1760_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
HKD1_k127_1760_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000253 228.0
HKD1_k127_1760_4 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000001042 222.0
HKD1_k127_1760_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000599 190.0
HKD1_k127_1760_6 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000678 168.0
HKD1_k127_1760_7 - - - - 0.0000000000000000000000000000000000000000001151 163.0
HKD1_k127_1760_8 - - - - 0.00000000000000000001828 94.0
HKD1_k127_1760_9 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000001773 82.0
HKD1_k127_177791_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
HKD1_k127_177791_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000004143 222.0
HKD1_k127_177791_2 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000002964 210.0
HKD1_k127_178039_0 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 484.0
HKD1_k127_178039_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 357.0
HKD1_k127_178039_2 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000005322 236.0
HKD1_k127_1816263_0 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 338.0
HKD1_k127_1816263_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 317.0
HKD1_k127_1816263_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 305.0
HKD1_k127_1816263_3 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000008571 164.0
HKD1_k127_1816263_4 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000001724 124.0
HKD1_k127_1816263_5 Belongs to the universal stress protein A family - - - 0.000000000000000000001964 99.0
HKD1_k127_1816263_6 Universal stress protein family - - - 0.0000000000000004023 85.0
HKD1_k127_183786_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1426.0
HKD1_k127_183786_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.923e-224 723.0
HKD1_k127_183786_10 Single Cache domain 2 K02660,K03406,K05875,K05876,K07216,K11525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 338.0
HKD1_k127_183786_11 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
HKD1_k127_183786_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 297.0
HKD1_k127_183786_13 NADPH-quinone reductase (modulator of drug activity B) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 286.0
HKD1_k127_183786_14 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
HKD1_k127_183786_15 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 263.0
HKD1_k127_183786_16 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HKD1_k127_183786_17 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001747 217.0
HKD1_k127_183786_18 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000001014 204.0
HKD1_k127_183786_19 radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000004213 201.0
HKD1_k127_183786_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 594.0
HKD1_k127_183786_20 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000006058 198.0
HKD1_k127_183786_21 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000005316 188.0
HKD1_k127_183786_23 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000002587 156.0
HKD1_k127_183786_24 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000000005026 147.0
HKD1_k127_183786_25 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000004646 142.0
HKD1_k127_183786_26 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000001561 116.0
HKD1_k127_183786_27 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000009291 84.0
HKD1_k127_183786_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000004765 74.0
HKD1_k127_183786_29 PFAM Ig domain protein group 2 domain protein - - - 0.000000000009227 77.0
HKD1_k127_183786_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 465.0
HKD1_k127_183786_30 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000392 75.0
HKD1_k127_183786_31 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000003527 61.0
HKD1_k127_183786_32 radical SAM domain protein - - - 0.00001996 51.0
HKD1_k127_183786_4 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 453.0
HKD1_k127_183786_5 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 384.0
HKD1_k127_183786_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 389.0
HKD1_k127_183786_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 345.0
HKD1_k127_183786_8 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 341.0
HKD1_k127_183786_9 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 325.0
HKD1_k127_1993714_0 Telomere recombination K04656 - - 1.438e-255 813.0
HKD1_k127_1993714_1 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 471.0
HKD1_k127_1993714_10 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000001532 137.0
HKD1_k127_1993714_11 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000000006359 125.0
HKD1_k127_1993714_12 YtxH-like protein - - - 0.0000000000000000000000000005512 117.0
HKD1_k127_1993714_14 - - - - 0.0000004734 52.0
HKD1_k127_1993714_2 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 440.0
HKD1_k127_1993714_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 419.0
HKD1_k127_1993714_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD1_k127_1993714_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 314.0
HKD1_k127_1993714_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009302 237.0
HKD1_k127_1993714_7 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000001094 233.0
HKD1_k127_1993714_8 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000002915 217.0
HKD1_k127_1993714_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000003559 203.0
HKD1_k127_2025246_0 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 3.541e-220 694.0
HKD1_k127_2025246_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 495.0
HKD1_k127_2025246_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 485.0
HKD1_k127_2025246_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 353.0
HKD1_k127_2025246_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 287.0
HKD1_k127_2025246_5 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
HKD1_k127_2025246_6 MgtC family K07507 - - 0.000000000000000000000000000000000000002058 156.0
HKD1_k127_2025246_8 major facilitator superfamily MFS_1 - - - 0.000000005044 58.0
HKD1_k127_2025246_9 Chlorophyllase - - - 0.00001154 57.0
HKD1_k127_2050086_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 509.0
HKD1_k127_2050086_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 428.0
HKD1_k127_2050086_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 391.0
HKD1_k127_2050086_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
HKD1_k127_2050086_4 Aminotransferase class I and II K14261 - - 0.00000000009996 62.0
HKD1_k127_2051796_0 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 549.0
HKD1_k127_2051796_1 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 317.0
HKD1_k127_2057184_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 466.0
HKD1_k127_2057184_1 Dehydrogenase K00248 - 1.3.8.1 0.0000000000005289 74.0
HKD1_k127_2071138_0 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
HKD1_k127_2071138_1 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000006333 169.0
HKD1_k127_2071138_2 BON domain - - - 0.00000000000000000000000963 108.0
HKD1_k127_2071138_3 Tetratricopeptide repeat - - - 0.00000000000179 76.0
HKD1_k127_2071138_4 Nitrite and sulphite reductase 4Fe-4S K11180,K11181 - 1.8.99.5 0.00000007531 53.0
HKD1_k127_2074116_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 546.0
HKD1_k127_2074116_1 ACT domain - - - 0.000000000000000000000000000000000000000000000000000000000152 206.0
HKD1_k127_2074116_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000009631 202.0
HKD1_k127_2074116_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000002175 156.0
HKD1_k127_2080048_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
HKD1_k127_2080048_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 316.0
HKD1_k127_2080048_10 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 - - 0.0000000000000000000000000000009344 132.0
HKD1_k127_2080048_11 Ribosomal protein S16 K02959 - - 0.00000000000000000000009594 99.0
HKD1_k127_2080048_12 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000001158 98.0
HKD1_k127_2080048_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 294.0
HKD1_k127_2080048_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
HKD1_k127_2080048_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007999 271.0
HKD1_k127_2080048_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003145 211.0
HKD1_k127_2080048_6 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000001192 211.0
HKD1_k127_2080048_7 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000002917 201.0
HKD1_k127_2080048_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003904 157.0
HKD1_k127_2080048_9 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000000002331 130.0
HKD1_k127_2081355_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.627e-230 722.0
HKD1_k127_2081355_1 Nickel-dependent hydrogenase - - - 1.367e-205 647.0
HKD1_k127_2081355_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000000000000000001994 190.0
HKD1_k127_2081355_11 - - - - 0.000000000000002193 82.0
HKD1_k127_2081355_12 Methylmuconolactone methyl-isomerase - - - 0.0000000000005491 74.0
HKD1_k127_2081355_13 - - - - 0.000000004514 57.0
HKD1_k127_2081355_14 His Kinase A (phosphoacceptor) domain - - - 0.0000008828 58.0
HKD1_k127_2081355_15 YMGG-like Gly-zipper - - - 0.00001606 54.0
HKD1_k127_2081355_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 574.0
HKD1_k127_2081355_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 477.0
HKD1_k127_2081355_4 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 466.0
HKD1_k127_2081355_5 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 457.0
HKD1_k127_2081355_6 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 404.0
HKD1_k127_2081355_7 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 402.0
HKD1_k127_2081355_8 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 303.0
HKD1_k127_2081355_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001816 226.0
HKD1_k127_2084631_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 436.0
HKD1_k127_2084631_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000001286 199.0
HKD1_k127_2084631_2 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000006109 193.0
HKD1_k127_2084631_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000005205 153.0
HKD1_k127_2084631_4 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000003549 144.0
HKD1_k127_2084631_5 Major facilitator superfamily - - - 0.00000000000000000000000000000002985 132.0
HKD1_k127_2084631_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000001601 123.0
HKD1_k127_2084631_7 Sulfurtransferase TusA - - - 0.000000000000000000000001056 106.0
HKD1_k127_2087267_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.894e-211 674.0
HKD1_k127_2087911_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.27e-281 881.0
HKD1_k127_2087911_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.93e-262 822.0
HKD1_k127_2087911_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 381.0
HKD1_k127_2087911_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001347 131.0
HKD1_k127_209980_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1804.0
HKD1_k127_209980_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 466.0
HKD1_k127_209980_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 287.0
HKD1_k127_209980_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003888 284.0
HKD1_k127_209980_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001488 257.0
HKD1_k127_209980_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000001915 225.0
HKD1_k127_209980_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000001009 192.0
HKD1_k127_209980_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000001164 51.0
HKD1_k127_209980_8 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000002758 59.0
HKD1_k127_2102580_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 422.0
HKD1_k127_2102580_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001606 271.0
HKD1_k127_2122567_0 SMART Elongator protein 3 MiaB NifB - - - 1.762e-197 647.0
HKD1_k127_2122567_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 432.0
HKD1_k127_2122567_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0007318 42.0
HKD1_k127_2130636_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 578.0
HKD1_k127_2130636_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 490.0
HKD1_k127_2143372_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 3.234e-233 733.0
HKD1_k127_2143372_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000006257 240.0
HKD1_k127_2174047_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.216e-283 882.0
HKD1_k127_2174047_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.884e-203 644.0
HKD1_k127_2174047_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000783 93.0
HKD1_k127_2174047_11 mercury ion transmembrane transporter activity K07213 - - 0.000000000000001004 79.0
HKD1_k127_2174047_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 507.0
HKD1_k127_2174047_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 492.0
HKD1_k127_2174047_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 463.0
HKD1_k127_2174047_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008347 253.0
HKD1_k127_2174047_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000008521 180.0
HKD1_k127_2174047_7 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000004272 152.0
HKD1_k127_2174047_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000005815 151.0
HKD1_k127_2190335_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 2.861e-320 984.0
HKD1_k127_2190335_1 Conserved region in glutamate synthase - - - 1.457e-277 859.0
HKD1_k127_2190335_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.544e-267 833.0
HKD1_k127_2190335_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 432.0
HKD1_k127_2190335_4 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
HKD1_k127_2190335_5 PFAM Glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 300.0
HKD1_k127_2190335_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000003309 177.0
HKD1_k127_2192851_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 361.0
HKD1_k127_2192851_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 349.0
HKD1_k127_2192851_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000001022 237.0
HKD1_k127_2218665_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000002424 186.0
HKD1_k127_2218665_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000006407 156.0
HKD1_k127_2219126_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 314.0
HKD1_k127_2219126_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001144 252.0
HKD1_k127_2219126_2 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000001369 214.0
HKD1_k127_2219126_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000003282 192.0
HKD1_k127_2219126_4 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000000002574 178.0
HKD1_k127_2219126_5 Thioredoxin-like - - - 0.0000000000000000000000000000000001395 137.0
HKD1_k127_2219126_7 cyclic nucleotide binding K10914 - - 0.000000000000000004561 87.0
HKD1_k127_2225693_0 COG2223 Nitrate nitrite transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
HKD1_k127_2225693_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000000884 158.0
HKD1_k127_2225693_2 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.000000000000000000000000000002597 129.0
HKD1_k127_2225693_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000001451 105.0
HKD1_k127_2225693_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0005948 42.0
HKD1_k127_2236347_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 329.0
HKD1_k127_2236347_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 282.0
HKD1_k127_2236347_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000001553 136.0
HKD1_k127_2236347_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000005342 88.0
HKD1_k127_229909_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.183e-219 698.0
HKD1_k127_229909_1 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 445.0
HKD1_k127_229909_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 366.0
HKD1_k127_229909_3 PIN domain - - - 0.00000000000000000000000000000000000000000000000001131 183.0
HKD1_k127_229909_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000000002211 113.0
HKD1_k127_229909_6 PFAM Rubrerythrin - - - 0.0004395 45.0
HKD1_k127_2312712_0 Elongation factor SelB, winged helix K03833 - - 1.876e-215 697.0
HKD1_k127_2312712_1 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
HKD1_k127_2312712_2 redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000001301 101.0
HKD1_k127_2312712_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000002995 70.0
HKD1_k127_2387416_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.354e-201 630.0
HKD1_k127_2387416_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 514.0
HKD1_k127_2387416_10 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000001597 68.0
HKD1_k127_2387416_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 399.0
HKD1_k127_2387416_3 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
HKD1_k127_2387416_4 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 328.0
HKD1_k127_2387416_5 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 317.0
HKD1_k127_2387416_6 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000002818 162.0
HKD1_k127_2387416_7 - - - - 0.000000000000000000000000000000000000004288 159.0
HKD1_k127_2387416_8 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000004966 105.0
HKD1_k127_2387416_9 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000002716 84.0
HKD1_k127_2399545_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 483.0
HKD1_k127_2399545_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 413.0
HKD1_k127_2399545_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000001426 187.0
HKD1_k127_2399545_3 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000374 143.0
HKD1_k127_2423304_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 548.0
HKD1_k127_2423304_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 478.0
HKD1_k127_2423304_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001048 197.0
HKD1_k127_2423304_11 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000000002071 146.0
HKD1_k127_2423304_12 Glutathione peroxidase - - - 0.00000000000000000000000000000000001818 140.0
HKD1_k127_2423304_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000327 148.0
HKD1_k127_2423304_14 PFAM Methyltransferase - - - 0.00000000000000000000000000000003389 126.0
HKD1_k127_2423304_15 DUF167 K09131 - - 0.0000000000004801 72.0
HKD1_k127_2423304_16 Nitrite and sulphite reductase 4Fe-4S K11180,K11181 - 1.8.99.5 0.00000007531 53.0
HKD1_k127_2423304_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 355.0
HKD1_k127_2423304_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 349.0
HKD1_k127_2423304_4 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006 275.0
HKD1_k127_2423304_5 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001083 244.0
HKD1_k127_2423304_6 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004679 244.0
HKD1_k127_2423304_7 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000003214 235.0
HKD1_k127_2423304_8 CGGC - - - 0.00000000000000000000000000000000000000000000000000000000002287 208.0
HKD1_k127_2423304_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000001781 205.0
HKD1_k127_2435219_0 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 355.0
HKD1_k127_2435219_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003099 237.0
HKD1_k127_2435219_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000002752 185.0
HKD1_k127_2435219_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000001098 134.0
HKD1_k127_2435219_4 response regulator - - - 0.00000000007033 68.0
HKD1_k127_2458140_0 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 555.0
HKD1_k127_2458140_1 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 428.0
HKD1_k127_2458140_2 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003791 266.0
HKD1_k127_2458140_3 PFAM peptidase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
HKD1_k127_2458140_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000004079 210.0
HKD1_k127_2510396_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 529.0
HKD1_k127_2510396_1 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000004618 151.0
HKD1_k127_2510396_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001796 139.0
HKD1_k127_2510396_4 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000002108 62.0
HKD1_k127_25288_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 516.0
HKD1_k127_25288_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 488.0
HKD1_k127_25288_10 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000003556 120.0
HKD1_k127_25288_11 Protein tyrosine serine phosphatase - - - 0.000000000000000000000000001491 124.0
HKD1_k127_25288_13 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000003867 110.0
HKD1_k127_25288_14 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000005033 99.0
HKD1_k127_25288_15 - - - - 0.000000001443 67.0
HKD1_k127_25288_16 Collagen triple helix repeat - - - 0.000000109 61.0
HKD1_k127_25288_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 432.0
HKD1_k127_25288_3 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 364.0
HKD1_k127_25288_4 Putative Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 336.0
HKD1_k127_25288_5 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 301.0
HKD1_k127_25288_6 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HKD1_k127_25288_7 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000283 234.0
HKD1_k127_25288_8 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
HKD1_k127_25288_9 - - - - 0.00000000000000000000000000000001876 134.0
HKD1_k127_2529460_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 557.0
HKD1_k127_2529460_1 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 445.0
HKD1_k127_2529460_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 295.0
HKD1_k127_2529460_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
HKD1_k127_2529460_4 NosL - - - 0.0000000000000000000000000000000004318 150.0
HKD1_k127_2529460_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000003261 79.0
HKD1_k127_2529460_6 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000003995 83.0
HKD1_k127_2529460_7 Predicted membrane protein (DUF2318) - - - 0.0000001665 58.0
HKD1_k127_2532118_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 518.0
HKD1_k127_2532118_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 452.0
HKD1_k127_2532118_2 LysM domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 349.0
HKD1_k127_2532118_3 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 291.0
HKD1_k127_2532118_4 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
HKD1_k127_2532118_5 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000000000001097 219.0
HKD1_k127_2532118_6 protein histidine kinase activity - - - 0.0000000000000000004503 95.0
HKD1_k127_2535382_0 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 584.0
HKD1_k127_2535382_1 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 532.0
HKD1_k127_2535382_10 Type II secretion system protein B K02451 - - 0.000000000000000000166 98.0
HKD1_k127_2535382_2 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 494.0
HKD1_k127_2535382_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 458.0
HKD1_k127_2535382_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 457.0
HKD1_k127_2535382_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 281.0
HKD1_k127_2535382_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 266.0
HKD1_k127_2535382_7 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000007847 195.0
HKD1_k127_2535382_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000008471 162.0
HKD1_k127_2535382_9 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000002472 126.0
HKD1_k127_2557646_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 515.0
HKD1_k127_2557646_1 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 458.0
HKD1_k127_2557646_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 397.0
HKD1_k127_2557646_3 K06861 lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 294.0
HKD1_k127_2557646_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
HKD1_k127_2557646_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007398 260.0
HKD1_k127_2557646_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000001026 197.0
HKD1_k127_2557646_7 AcrB/AcrD/AcrF family K03296,K18138 - - 0.00000000000000000000000000000000000000000000005106 170.0
HKD1_k127_2557646_8 OstA-like protein K09774 - - 0.000000000000000000000000000000001491 135.0
HKD1_k127_2557646_9 InterPro IPR010664 - - - 0.0005328 49.0
HKD1_k127_2649590_0 Belongs to the peptidase S16 family - - - 1.579e-218 705.0
HKD1_k127_2649590_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 484.0
HKD1_k127_2649590_10 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000001824 188.0
HKD1_k127_2649590_11 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000001141 176.0
HKD1_k127_2649590_12 - - - - 0.000000000000000000000000004814 114.0
HKD1_k127_2649590_13 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000005076 109.0
HKD1_k127_2649590_14 - - - - 0.000000000000000000001013 101.0
HKD1_k127_2649590_15 hydrogenase maturation protease K03605 - - 0.00000000000004463 76.0
HKD1_k127_2649590_16 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.0000000001037 68.0
HKD1_k127_2649590_17 Diguanylate cyclase - - - 0.00000006132 53.0
HKD1_k127_2649590_18 Transcription factor zinc-finger K09981 - - 0.000004514 51.0
HKD1_k127_2649590_19 Domain of unknown function (DUF4124) - - - 0.000006107 54.0
HKD1_k127_2649590_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 473.0
HKD1_k127_2649590_20 hydrogenase maturation protease K03605 - - 0.00001184 51.0
HKD1_k127_2649590_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 338.0
HKD1_k127_2649590_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
HKD1_k127_2649590_5 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000001535 270.0
HKD1_k127_2649590_6 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002826 250.0
HKD1_k127_2649590_7 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
HKD1_k127_2649590_8 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
HKD1_k127_2649590_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000009046 195.0
HKD1_k127_2653183_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 452.0
HKD1_k127_2653183_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000004084 199.0
HKD1_k127_2663307_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.195e-218 682.0
HKD1_k127_2663307_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 404.0
HKD1_k127_2663307_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004984 200.0
HKD1_k127_2663307_11 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000001506 197.0
HKD1_k127_2663307_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000001606 173.0
HKD1_k127_2663307_13 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000002406 174.0
HKD1_k127_2663307_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000002722 169.0
HKD1_k127_2663307_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000128 162.0
HKD1_k127_2663307_16 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000006574 149.0
HKD1_k127_2663307_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000499 129.0
HKD1_k127_2663307_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000003787 112.0
HKD1_k127_2663307_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009633 104.0
HKD1_k127_2663307_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 331.0
HKD1_k127_2663307_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003418 104.0
HKD1_k127_2663307_21 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000008779 79.0
HKD1_k127_2663307_22 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002956 71.0
HKD1_k127_2663307_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000007389 48.0
HKD1_k127_2663307_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 322.0
HKD1_k127_2663307_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
HKD1_k127_2663307_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000285 282.0
HKD1_k127_2663307_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005158 227.0
HKD1_k127_2663307_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001507 228.0
HKD1_k127_2663307_8 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000007425 228.0
HKD1_k127_2663307_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000008656 220.0
HKD1_k127_269236_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 508.0
HKD1_k127_269236_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 421.0
HKD1_k127_269236_11 Histidine kinase - - - 0.0000000459 65.0
HKD1_k127_269236_2 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 333.0
HKD1_k127_269236_3 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000006728 179.0
HKD1_k127_269236_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000009692 162.0
HKD1_k127_269236_5 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000005362 110.0
HKD1_k127_269236_6 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000019 105.0
HKD1_k127_269236_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000002364 91.0
HKD1_k127_269236_8 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000005837 97.0
HKD1_k127_269236_9 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000001487 64.0
HKD1_k127_280496_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 415.0
HKD1_k127_280496_2 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
HKD1_k127_280496_3 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000009664 236.0
HKD1_k127_280496_4 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000003239 174.0
HKD1_k127_280496_5 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000005266 161.0
HKD1_k127_280496_6 BON domain - - - 0.0000000000000000000000005336 109.0
HKD1_k127_280496_7 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.00000000000000004268 91.0
HKD1_k127_280496_8 Tetratricopeptide repeat - - - 0.000000000003404 76.0
HKD1_k127_280496_9 - - - - 0.00002032 48.0
HKD1_k127_28708_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 517.0
HKD1_k127_28708_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 284.0
HKD1_k127_28708_2 Protein involved in formate dehydrogenase formation K02380 - - 0.00000001723 58.0
HKD1_k127_3020033_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003938 286.0
HKD1_k127_3020033_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
HKD1_k127_3020033_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000006119 167.0
HKD1_k127_3020033_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000001412 63.0
HKD1_k127_3023039_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 381.0
HKD1_k127_3023039_1 chemotaxis protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 345.0
HKD1_k127_3023039_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005935 252.0
HKD1_k127_3023039_3 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000006191 232.0
HKD1_k127_3023039_4 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000000000000000005511 209.0
HKD1_k127_3023039_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000000005397 184.0
HKD1_k127_3023039_6 ABC transporter K01989 - - 0.00000000000000000000000000000000000000000004064 175.0
HKD1_k127_3023039_7 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000003729 155.0
HKD1_k127_3023039_8 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000001872 146.0
HKD1_k127_3023039_9 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000003744 141.0
HKD1_k127_3029634_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 9.446e-228 712.0
HKD1_k127_3029634_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 325.0
HKD1_k127_3029634_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000006814 244.0
HKD1_k127_3029634_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
HKD1_k127_3029634_4 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000004033 170.0
HKD1_k127_3029634_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000001539 98.0
HKD1_k127_3029634_6 domain protein - - - 0.00000000000000000001998 107.0
HKD1_k127_3029634_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000001101 82.0
HKD1_k127_3029634_8 Predicted RNA-binding protein - - - 0.000000000000007102 77.0
HKD1_k127_3033656_0 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 323.0
HKD1_k127_3033656_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000001033 104.0
HKD1_k127_3033656_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000003574 80.0
HKD1_k127_3056921_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 502.0
HKD1_k127_3056921_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
HKD1_k127_3056921_2 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000006504 51.0
HKD1_k127_3070991_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 517.0
HKD1_k127_3070991_1 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 414.0
HKD1_k127_3070991_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 387.0
HKD1_k127_3070991_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 364.0
HKD1_k127_308283_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 499.0
HKD1_k127_308283_1 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 469.0
HKD1_k127_308283_10 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000004423 99.0
HKD1_k127_308283_11 AhpC/TSA family K03386 - 1.11.1.15 0.00000003778 56.0
HKD1_k127_308283_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
HKD1_k127_308283_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HKD1_k127_308283_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000835 219.0
HKD1_k127_308283_5 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000000003165 181.0
HKD1_k127_308283_6 GYD domain - - - 0.000000000000000000000000000000000000135 143.0
HKD1_k127_308283_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000008739 133.0
HKD1_k127_308283_8 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000000001123 108.0
HKD1_k127_308283_9 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000196 110.0
HKD1_k127_3094195_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
HKD1_k127_3094195_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 308.0
HKD1_k127_3094195_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003443 274.0
HKD1_k127_3094195_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000003421 203.0
HKD1_k127_3094195_4 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000006665 198.0
HKD1_k127_3094195_5 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000003086 137.0
HKD1_k127_3094195_6 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000004356 102.0
HKD1_k127_3101406_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 4.587e-201 640.0
HKD1_k127_3101406_1 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000009164 121.0
HKD1_k127_3112912_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 592.0
HKD1_k127_3112912_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 591.0
HKD1_k127_3112912_2 poly-beta-hydroxybutyrate polymerase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 449.0
HKD1_k127_3112912_3 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 313.0
HKD1_k127_3112912_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008398 239.0
HKD1_k127_3112912_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000005302 161.0
HKD1_k127_3112912_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000001178 83.0
HKD1_k127_3112912_7 Protein of unknown function (DUF2892) - - - 0.000000001555 66.0
HKD1_k127_3112912_8 ATP synthase B/B' CF(0) K02109 - - 0.00006355 52.0
HKD1_k127_3112912_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0002881 46.0
HKD1_k127_3163660_0 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 401.0
HKD1_k127_3163660_2 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000259 153.0
HKD1_k127_3163660_3 transcriptional regulator - - - 0.00000000000000000000000000000000006703 138.0
HKD1_k127_3163660_4 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000001899 120.0
HKD1_k127_3179509_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
HKD1_k127_3179509_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 302.0
HKD1_k127_3179509_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000003507 187.0
HKD1_k127_3179509_3 Domain of unknown function (DUF4388) - - - 0.00000000000000000000002582 105.0
HKD1_k127_3179509_4 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000375 93.0
HKD1_k127_3179509_6 Protein of unknown function (DUF2934) - - - 0.000001405 55.0
HKD1_k127_3179509_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. K21685 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006082,GO:0006083,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016999,GO:0017144,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000003869 56.0
HKD1_k127_3179509_8 PFAM Prenyltransferase squalene oxidase - - - 0.00000511 58.0
HKD1_k127_3180423_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1356.0
HKD1_k127_3180423_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1304.0
HKD1_k127_3180423_10 NADH dehydrogenase K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000004064 136.0
HKD1_k127_3180423_11 Methyltransferase domain - - - 0.000000000000000000000000000001441 130.0
HKD1_k127_3180423_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.988e-258 802.0
HKD1_k127_3180423_3 Belongs to the glycosyl hydrolase 57 family - - - 2.622e-257 809.0
HKD1_k127_3180423_4 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 3.352e-205 669.0
HKD1_k127_3180423_5 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 586.0
HKD1_k127_3180423_6 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 516.0
HKD1_k127_3180423_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 441.0
HKD1_k127_3180423_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
HKD1_k127_3180423_9 Molybdopterin oxidoreductase, Fe4S4 K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000001428 138.0
HKD1_k127_3245629_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
HKD1_k127_3245629_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000005014 251.0
HKD1_k127_3245629_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000003393 200.0
HKD1_k127_3249539_0 Curli production assembly transport component CsgG K04087 - - 0.0000000000000000000000000000000000000000000000000000000000003119 223.0
HKD1_k127_3249539_1 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000000000000000004348 165.0
HKD1_k127_3249539_2 denitrification pathway - - - 0.000000000000000000000000000000000000000273 164.0
HKD1_k127_3249539_3 12 heme-binding sites - - - 0.000000000000000000000000000000000000001015 154.0
HKD1_k127_3249539_4 - - - - 0.00000000000000000000000000004094 123.0
HKD1_k127_3249539_5 - - - - 0.0000000001951 72.0
HKD1_k127_3249539_6 FecR protein - - - 0.00001333 57.0
HKD1_k127_3255956_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 481.0
HKD1_k127_3255956_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 394.0
HKD1_k127_3255956_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
HKD1_k127_3255956_3 nucleotide metabolic process - - - 0.00000000000000000000000000002682 125.0
HKD1_k127_3260710_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 567.0
HKD1_k127_3260710_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
HKD1_k127_3260710_10 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000000000003795 101.0
HKD1_k127_3260710_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 321.0
HKD1_k127_3260710_3 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 255.0
HKD1_k127_3260710_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000009271 192.0
HKD1_k127_3260710_5 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000736 179.0
HKD1_k127_3260710_6 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000000000004003 161.0
HKD1_k127_3260710_7 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000001401 149.0
HKD1_k127_3260710_8 - - - - 0.00000000000000000000000000000001123 131.0
HKD1_k127_3260710_9 - - - - 0.000000000000000000000000000001245 127.0
HKD1_k127_3288688_0 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 494.0
HKD1_k127_3288688_1 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000000004851 210.0
HKD1_k127_3288688_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000008676 129.0
HKD1_k127_3288688_3 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000001801 123.0
HKD1_k127_3343660_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 3.107e-205 651.0
HKD1_k127_3343660_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 602.0
HKD1_k127_3343660_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 560.0
HKD1_k127_3343660_3 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 466.0
HKD1_k127_3343660_4 - - - - 0.00000000000000000000000000000000000002714 151.0
HKD1_k127_3361079_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000345 172.0
HKD1_k127_3361079_1 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15554 - - 0.000000000000000000000000000000000000000559 159.0
HKD1_k127_3361079_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000054 158.0
HKD1_k127_3361079_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000009294 125.0
HKD1_k127_3368887_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 406.0
HKD1_k127_3368887_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 397.0
HKD1_k127_3372576_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 550.0
HKD1_k127_3372576_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 451.0
HKD1_k127_3372576_2 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 394.0
HKD1_k127_3375251_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 523.0
HKD1_k127_3375251_1 - - - - 0.0000000000000000000000000000000000002896 161.0
HKD1_k127_3375251_2 helix_turn_helix, arabinose operon control protein K07720 - - 0.000007411 49.0
HKD1_k127_3394758_0 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 501.0
HKD1_k127_3394758_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 477.0
HKD1_k127_3394758_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000007913 76.0
HKD1_k127_3394758_11 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000003583 49.0
HKD1_k127_3394758_2 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 424.0
HKD1_k127_3394758_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 346.0
HKD1_k127_3394758_4 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
HKD1_k127_3394758_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
HKD1_k127_3394758_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001624 255.0
HKD1_k127_3394758_7 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000001046 120.0
HKD1_k127_3394758_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000003545 114.0
HKD1_k127_3394758_9 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.0000000000000000000000001262 109.0
HKD1_k127_3413372_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 482.0
HKD1_k127_3413372_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 357.0
HKD1_k127_3413372_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 311.0
HKD1_k127_3413372_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000004963 170.0
HKD1_k127_3413372_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000001872 88.0
HKD1_k127_3421865_0 PFAM ABC transporter related K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 502.0
HKD1_k127_3421865_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 455.0
HKD1_k127_3421865_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
HKD1_k127_3421865_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 284.0
HKD1_k127_34281_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 1.309e-254 788.0
HKD1_k127_34281_1 Sigma54 specific transcriptional regulator, Fis family - - - 8.791e-224 707.0
HKD1_k127_34281_2 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 434.0
HKD1_k127_34281_3 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 394.0
HKD1_k127_34281_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 251.0
HKD1_k127_34281_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000001285 229.0
HKD1_k127_34281_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000005858 96.0
HKD1_k127_34281_7 helix_turn_helix, Lux Regulon - - - 0.0000000002685 68.0
HKD1_k127_3432678_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1092.0
HKD1_k127_3432678_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 365.0
HKD1_k127_3432678_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001396 271.0
HKD1_k127_3432678_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
HKD1_k127_3432678_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000007114 70.0
HKD1_k127_3432678_5 chlorophyll binding - - - 0.0000000001528 64.0
HKD1_k127_3432678_6 chlorophyll binding - - - 0.0005692 43.0
HKD1_k127_3518492_0 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 8.721e-201 636.0
HKD1_k127_3518492_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 393.0
HKD1_k127_3518492_2 Protein of unknown function DUF116 - - - 0.000000000000000003197 93.0
HKD1_k127_3536083_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 472.0
HKD1_k127_3536083_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 392.0
HKD1_k127_3536083_2 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.00000000000000000118 87.0
HKD1_k127_3536083_3 Integrase core domain K07497 - - 0.000001289 53.0
HKD1_k127_3537605_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 355.0
HKD1_k127_3537605_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
HKD1_k127_3537605_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
HKD1_k127_3537605_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000004039 226.0
HKD1_k127_3537605_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000001837 142.0
HKD1_k127_354312_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 288.0
HKD1_k127_354312_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005902 136.0
HKD1_k127_3557238_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 528.0
HKD1_k127_3557238_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 330.0
HKD1_k127_3557238_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
HKD1_k127_3557238_3 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006808 282.0
HKD1_k127_3557238_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000003675 221.0
HKD1_k127_3557238_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000001302 231.0
HKD1_k127_3557238_6 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000002063 180.0
HKD1_k127_3557238_7 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000006111 145.0
HKD1_k127_3557238_8 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000008455 133.0
HKD1_k127_3557238_9 PFAM CheW domain protein K03408 - - 0.00000000000000000001619 99.0
HKD1_k127_3591779_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.735e-225 707.0
HKD1_k127_3591779_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 2.209e-199 629.0
HKD1_k127_3591779_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
HKD1_k127_3591779_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000081 240.0
HKD1_k127_3591779_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001165 237.0
HKD1_k127_3591779_5 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000002499 91.0
HKD1_k127_3591779_7 - - - - 0.000000000006586 75.0
HKD1_k127_3608366_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.963e-299 923.0
HKD1_k127_3608366_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.801e-231 751.0
HKD1_k127_3608366_10 CoA-binding domain K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 473.0
HKD1_k127_3608366_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 437.0
HKD1_k127_3608366_12 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 424.0
HKD1_k127_3608366_13 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 381.0
HKD1_k127_3608366_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
HKD1_k127_3608366_15 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 347.0
HKD1_k127_3608366_16 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 354.0
HKD1_k127_3608366_17 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 338.0
HKD1_k127_3608366_18 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 319.0
HKD1_k127_3608366_19 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 323.0
HKD1_k127_3608366_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.216e-204 645.0
HKD1_k127_3608366_20 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 300.0
HKD1_k127_3608366_21 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 291.0
HKD1_k127_3608366_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 302.0
HKD1_k127_3608366_23 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 307.0
HKD1_k127_3608366_24 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 261.0
HKD1_k127_3608366_25 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004241 270.0
HKD1_k127_3608366_26 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HKD1_k127_3608366_27 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000001746 207.0
HKD1_k127_3608366_28 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000003722 180.0
HKD1_k127_3608366_29 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000051 180.0
HKD1_k127_3608366_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 586.0
HKD1_k127_3608366_30 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000263 186.0
HKD1_k127_3608366_31 Flagellar hook protein flgE - - - 0.0000000000000000000000000000000000000000003348 181.0
HKD1_k127_3608366_32 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000009117 141.0
HKD1_k127_3608366_33 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000004233 134.0
HKD1_k127_3608366_34 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.5.4.5 0.0000000000000000000000000000000002353 135.0
HKD1_k127_3608366_35 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000006109 133.0
HKD1_k127_3608366_36 cellulase activity - - - 0.0000000000000000000000000000000885 144.0
HKD1_k127_3608366_37 glutamate synthase - - - 0.0000000000000000000000000000003982 142.0
HKD1_k127_3608366_38 Tetratricopeptide repeat - - - 0.0000000000000000000000004556 115.0
HKD1_k127_3608366_39 Protein of unknown function, DUF488 - - - 0.00000000000000002315 86.0
HKD1_k127_3608366_4 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 563.0
HKD1_k127_3608366_40 Fimbrial assembly protein (PilN) - - - 0.0000000002293 73.0
HKD1_k127_3608366_41 Type II secretion system (T2SS), protein M subtype b - - - 0.00000002416 63.0
HKD1_k127_3608366_42 - - - - 0.0000000306 63.0
HKD1_k127_3608366_43 CAAX protease self-immunity K07052 - - 0.00000005252 61.0
HKD1_k127_3608366_44 type IV pilus modification protein PilV K02458 - - 0.0000003431 59.0
HKD1_k127_3608366_45 fimbrial assembly K02461 - - 0.000006942 59.0
HKD1_k127_3608366_46 General secretion pathway protein H K02457 - - 0.000008304 54.0
HKD1_k127_3608366_5 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 550.0
HKD1_k127_3608366_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 529.0
HKD1_k127_3608366_7 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 540.0
HKD1_k127_3608366_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 493.0
HKD1_k127_3608366_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 480.0
HKD1_k127_3640217_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009105 255.0
HKD1_k127_3640217_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000005113 199.0
HKD1_k127_3640217_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000001745 130.0
HKD1_k127_3753134_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 487.0
HKD1_k127_3753134_1 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00002189 53.0
HKD1_k127_3922733_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1196.0
HKD1_k127_3922733_1 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000000000368 188.0
HKD1_k127_3922733_2 - - - - 0.00000000000000000000000000000000000000003346 159.0
HKD1_k127_3922733_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000006802 156.0
HKD1_k127_3922733_4 - - - - 0.0000000000000000000000000000000005689 135.0
HKD1_k127_3922733_5 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000000002458 104.0
HKD1_k127_3922733_6 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000002778 72.0
HKD1_k127_3922733_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002052 70.0
HKD1_k127_395098_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000005746 212.0
HKD1_k127_395098_1 COG1450 Type II secretory pathway, component PulD K02453 - - 0.00000000000002868 83.0
HKD1_k127_400298_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 3.294e-203 642.0
HKD1_k127_400298_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001565 250.0
HKD1_k127_400298_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000001667 163.0
HKD1_k127_4026610_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.009e-299 927.0
HKD1_k127_4026610_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 610.0
HKD1_k127_4026610_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
HKD1_k127_4026610_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 264.0
HKD1_k127_4026610_4 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000275 263.0
HKD1_k127_4026610_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
HKD1_k127_4026610_6 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000007048 202.0
HKD1_k127_4026610_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000001261 65.0
HKD1_k127_4026610_8 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000003078 64.0
HKD1_k127_4026610_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000005866 54.0
HKD1_k127_4030978_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 363.0
HKD1_k127_4030978_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000189 172.0
HKD1_k127_4030978_2 OmpA family K02557 - - 0.0005282 50.0
HKD1_k127_4037555_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 586.0
HKD1_k127_4037555_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 440.0
HKD1_k127_4037555_10 Protein of unknown function (DUF3623) - - - 0.0000000000000000000000000000000000003043 151.0
HKD1_k127_4037555_11 OsmC-like protein - - - 0.00000000000000007471 87.0
HKD1_k127_4037555_12 cheY-homologous receiver domain - - - 0.0001589 49.0
HKD1_k127_4037555_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 382.0
HKD1_k127_4037555_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 329.0
HKD1_k127_4037555_4 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 308.0
HKD1_k127_4037555_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 306.0
HKD1_k127_4037555_6 - - - - 0.00000000000000000000000000000000000000000000000000000000001536 213.0
HKD1_k127_4037555_7 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000004423 174.0
HKD1_k127_4037555_8 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000002696 158.0
HKD1_k127_4037555_9 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000001498 150.0
HKD1_k127_4047404_0 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 5.445e-244 770.0
HKD1_k127_4047404_1 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 578.0
HKD1_k127_4047404_2 Protein of unknown function DUF116 - - - 0.00000000000000000000000000000000000016 151.0
HKD1_k127_4051053_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.305e-247 772.0
HKD1_k127_4051053_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 536.0
HKD1_k127_4051053_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 334.0
HKD1_k127_4051053_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 297.0
HKD1_k127_4051053_4 COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000001889 236.0
HKD1_k127_4051053_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000002104 213.0
HKD1_k127_4051053_6 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000000000000000000000004781 213.0
HKD1_k127_4051053_7 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000001364 191.0
HKD1_k127_4054043_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 502.0
HKD1_k127_4054043_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 464.0
HKD1_k127_4054043_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
HKD1_k127_4054043_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006388 277.0
HKD1_k127_4054043_4 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000003538 174.0
HKD1_k127_4054043_5 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000005068 126.0
HKD1_k127_4063911_0 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 604.0
HKD1_k127_4063911_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 587.0
HKD1_k127_4063911_10 - - - - 0.0000000000000000000000000000000000000000000000000000001248 203.0
HKD1_k127_4063911_11 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.000000000000000000000000000000000000000000000000000001717 200.0
HKD1_k127_4063911_12 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000003942 186.0
HKD1_k127_4063911_13 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000005954 177.0
HKD1_k127_4063911_14 Pentapeptide repeats (9 copies) - - - 0.000000000000000002862 93.0
HKD1_k127_4063911_15 Transcriptional regulator K02584 - - 0.00000000007315 63.0
HKD1_k127_4063911_16 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000002678 61.0
HKD1_k127_4063911_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 497.0
HKD1_k127_4063911_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 474.0
HKD1_k127_4063911_4 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 434.0
HKD1_k127_4063911_5 aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 374.0
HKD1_k127_4063911_6 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
HKD1_k127_4063911_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 297.0
HKD1_k127_4063911_8 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001089 273.0
HKD1_k127_4063911_9 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HKD1_k127_4081738_0 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 380.0
HKD1_k127_4081738_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000002441 189.0
HKD1_k127_4081738_2 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000001531 179.0
HKD1_k127_4081738_3 Pfam:N_methyl_2 K02459 - - 0.00000000004596 72.0
HKD1_k127_4081738_4 type IV pilus modification protein PilV K02458 - - 0.00002022 54.0
HKD1_k127_4081738_5 general secretion pathway protein K02457 - - 0.0000608 53.0
HKD1_k127_4084109_0 Glycosyl hydrolase family 57 - - - 4.048e-221 708.0
HKD1_k127_4084109_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.469e-195 616.0
HKD1_k127_4084109_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000003275 129.0
HKD1_k127_4084109_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000004157 134.0
HKD1_k127_4084109_12 cell cycle K05589,K12065,K13052 - - 0.000000000000000001925 88.0
HKD1_k127_4084109_13 heat shock protein binding - - - 0.00000000000001505 87.0
HKD1_k127_4084109_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 578.0
HKD1_k127_4084109_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
HKD1_k127_4084109_4 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 501.0
HKD1_k127_4084109_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 423.0
HKD1_k127_4084109_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 354.0
HKD1_k127_4084109_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 342.0
HKD1_k127_4084109_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
HKD1_k127_4084109_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000008954 184.0
HKD1_k127_4104654_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 379.0
HKD1_k127_4104654_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000001528 243.0
HKD1_k127_4104654_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000005628 215.0
HKD1_k127_4108146_0 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000002504 213.0
HKD1_k127_4108146_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000164 200.0
HKD1_k127_4108146_2 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000003208 148.0
HKD1_k127_4108743_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 438.0
HKD1_k127_4108743_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 376.0
HKD1_k127_4108743_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 312.0
HKD1_k127_4108743_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000009407 221.0
HKD1_k127_4108743_4 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000001303 170.0
HKD1_k127_4112446_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 594.0
HKD1_k127_4112446_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 577.0
HKD1_k127_4112446_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000003983 155.0
HKD1_k127_4112446_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000001894 85.0
HKD1_k127_4112446_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00001758 52.0
HKD1_k127_4112446_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0002881 46.0
HKD1_k127_4113704_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 353.0
HKD1_k127_4113704_1 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000169 149.0
HKD1_k127_4113704_2 lyase activity - - - 0.0000000000000000000000000001586 131.0
HKD1_k127_4116960_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 436.0
HKD1_k127_4116960_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 391.0
HKD1_k127_4116960_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
HKD1_k127_4116960_3 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
HKD1_k127_4116960_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000001439 161.0
HKD1_k127_4116960_5 Cytochrome c K08906,K12263 - - 0.00000000000000000000007225 104.0
HKD1_k127_4116960_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000004535 93.0
HKD1_k127_4118230_0 membrane transporter protein K07090 - - 2.297e-207 652.0
HKD1_k127_4118230_1 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 499.0
HKD1_k127_4118230_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
HKD1_k127_4118230_3 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 245.0
HKD1_k127_4118230_4 - - - - 0.00000000000000000000008356 98.0
HKD1_k127_4118230_5 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000003767 104.0
HKD1_k127_4129508_0 membrane - - - 8.365e-260 812.0
HKD1_k127_4129508_1 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000002078 164.0
HKD1_k127_4129508_2 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000001987 115.0
HKD1_k127_4129508_3 - - - - 0.00000007335 54.0
HKD1_k127_4131531_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 5.494e-235 738.0
HKD1_k127_4131531_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 611.0
HKD1_k127_4131531_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000003791 186.0
HKD1_k127_4131531_11 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000003268 174.0
HKD1_k127_4131531_13 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000003147 118.0
HKD1_k127_4131531_14 - - - - 0.000000000000000000000000002165 121.0
HKD1_k127_4131531_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000003644 117.0
HKD1_k127_4131531_16 - - - - 0.00000000000000000000000001705 110.0
HKD1_k127_4131531_17 PFAM membrane protein of K08972 - - 0.0000000000000000000000006239 108.0
HKD1_k127_4131531_18 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000009275 103.0
HKD1_k127_4131531_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000005162 101.0
HKD1_k127_4131531_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 603.0
HKD1_k127_4131531_21 - - - - 0.000000000009702 70.0
HKD1_k127_4131531_3 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 595.0
HKD1_k127_4131531_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 555.0
HKD1_k127_4131531_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 494.0
HKD1_k127_4131531_6 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 378.0
HKD1_k127_4131531_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 310.0
HKD1_k127_4131531_8 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
HKD1_k127_4131531_9 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000001478 216.0
HKD1_k127_4133541_0 Belongs to the glycosyl hydrolase 57 family - - - 4.018e-203 651.0
HKD1_k127_4133541_1 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 7.77e-197 619.0
HKD1_k127_4133541_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000003564 169.0
HKD1_k127_4133541_11 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000001581 153.0
HKD1_k127_4133541_12 ethanolamine kinase activity K07251 - 2.7.1.89 0.00000000000000000000000000000000003693 148.0
HKD1_k127_4133541_13 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000000001365 124.0
HKD1_k127_4133541_14 - - - - 0.00000000000000000000002353 110.0
HKD1_k127_4133541_15 Transglycosylase SLT domain - - - 0.00000000000000003984 89.0
HKD1_k127_4133541_16 - - - - 0.0000000000000431 72.0
HKD1_k127_4133541_18 Protein of unknown function (DUF3096) - - - 0.0000000005415 61.0
HKD1_k127_4133541_19 - - - - 0.0000005274 57.0
HKD1_k127_4133541_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 592.0
HKD1_k127_4133541_20 - - - - 0.00001482 52.0
HKD1_k127_4133541_3 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 556.0
HKD1_k127_4133541_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 529.0
HKD1_k127_4133541_5 growth of symbiont in host cell K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 520.0
HKD1_k127_4133541_6 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 446.0
HKD1_k127_4133541_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 373.0
HKD1_k127_4133541_8 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000006844 206.0
HKD1_k127_4133541_9 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.0000000000000000000000000000000000000000000007036 171.0
HKD1_k127_4135570_0 PFAM major facilitator superfamily MFS_1 K02575 - - 1.468e-245 764.0
HKD1_k127_4135570_1 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 6.985e-235 734.0
HKD1_k127_4135570_2 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
HKD1_k127_4135570_3 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.0000000000000000000000000000000000000001543 157.0
HKD1_k127_4135570_4 DsrC like protein - - - 0.000000000000000000000005569 108.0
HKD1_k127_4135570_5 PFAM nitrite and sulphite reductase 4Fe-4S K11180 GO:0005575,GO:0016020 1.8.99.5 0.00000001733 60.0
HKD1_k127_4138709_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 514.0
HKD1_k127_4138709_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005705 256.0
HKD1_k127_4138709_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000003084 222.0
HKD1_k127_4140884_0 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 469.0
HKD1_k127_4140884_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 351.0
HKD1_k127_4140884_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003564 277.0
HKD1_k127_4140884_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000004458 200.0
HKD1_k127_4140884_4 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000009234 140.0
HKD1_k127_4140884_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000001641 79.0
HKD1_k127_4161224_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 9.736e-208 656.0
HKD1_k127_4161224_1 Sensory domain found in PocR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 528.0
HKD1_k127_4161224_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000007747 191.0
HKD1_k127_4161224_11 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000005835 168.0
HKD1_k127_4161224_12 response regulator - - - 0.000000000000000001839 99.0
HKD1_k127_4161224_14 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00002705 47.0
HKD1_k127_4161224_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 444.0
HKD1_k127_4161224_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 399.0
HKD1_k127_4161224_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
HKD1_k127_4161224_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000004007 249.0
HKD1_k127_4161224_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000002935 239.0
HKD1_k127_4161224_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
HKD1_k127_4161224_8 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000007509 224.0
HKD1_k127_4161224_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
HKD1_k127_4210317_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 580.0
HKD1_k127_4210317_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 415.0
HKD1_k127_4210317_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
HKD1_k127_4210317_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 353.0
HKD1_k127_4210317_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 322.0
HKD1_k127_4210317_5 SMART Cold shock protein K03704 - - 0.000000000000000000000000003112 111.0
HKD1_k127_4260868_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.095e-245 765.0
HKD1_k127_4260868_1 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 449.0
HKD1_k127_4260868_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 413.0
HKD1_k127_4260868_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 324.0
HKD1_k127_4260868_4 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000002063 172.0
HKD1_k127_4260868_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000003419 153.0
HKD1_k127_4260868_6 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000001048 128.0
HKD1_k127_4260868_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000003826 124.0
HKD1_k127_4273218_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 596.0
HKD1_k127_4273218_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
HKD1_k127_4273218_2 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005435 263.0
HKD1_k127_4273218_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000004408 244.0
HKD1_k127_4273218_4 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
HKD1_k127_4273218_5 response regulator, receiver K03413 - - 0.0000000000000000000000000000252 122.0
HKD1_k127_4274191_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 363.0
HKD1_k127_4274191_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 342.0
HKD1_k127_4274191_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000006554 129.0
HKD1_k127_4283687_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1153.0
HKD1_k127_4283687_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 331.0
HKD1_k127_4283687_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
HKD1_k127_4283687_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000001855 139.0
HKD1_k127_4283687_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000001137 96.0
HKD1_k127_4283687_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000006045 76.0
HKD1_k127_4335661_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 290.0
HKD1_k127_4335661_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 282.0
HKD1_k127_4337276_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.369e-244 764.0
HKD1_k127_4337276_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.167e-228 714.0
HKD1_k127_4337276_10 Nuclease-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 319.0
HKD1_k127_4337276_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
HKD1_k127_4337276_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004387 282.0
HKD1_k127_4337276_13 Transketolase, thiamine diphosphate binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001949 282.0
HKD1_k127_4337276_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000001836 260.0
HKD1_k127_4337276_15 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007622 248.0
HKD1_k127_4337276_16 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004138 255.0
HKD1_k127_4337276_17 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
HKD1_k127_4337276_18 Uncharacterized conserved protein (DUF2075) - - - 0.00000000000000000000000000000000000000000000000000000000000001727 216.0
HKD1_k127_4337276_19 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000005845 205.0
HKD1_k127_4337276_2 Sigma-54 factor interaction domain-containing protein K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 561.0
HKD1_k127_4337276_20 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000001056 204.0
HKD1_k127_4337276_21 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000001522 187.0
HKD1_k127_4337276_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000001064 181.0
HKD1_k127_4337276_23 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000002357 166.0
HKD1_k127_4337276_24 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000002184 169.0
HKD1_k127_4337276_25 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.00000000000000000000000000000000000000007813 162.0
HKD1_k127_4337276_26 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000003776 160.0
HKD1_k127_4337276_27 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000002569 143.0
HKD1_k127_4337276_28 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.00000000000000000000000000000000004138 143.0
HKD1_k127_4337276_29 Sulphur transport - - - 0.0000000000000000000000000000000000893 139.0
HKD1_k127_4337276_3 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 540.0
HKD1_k127_4337276_30 - - - - 0.0000000000000000000000000000007466 128.0
HKD1_k127_4337276_31 Sulfurtransferase TusA - - - 0.0000000000000000000002443 98.0
HKD1_k127_4337276_32 - - - - 0.0000000000000000001321 94.0
HKD1_k127_4337276_33 His Kinase A (phosphoacceptor) domain - - - 0.00000000117 70.0
HKD1_k127_4337276_34 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000002759 68.0
HKD1_k127_4337276_35 TPR repeat - - - 0.000004449 59.0
HKD1_k127_4337276_4 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 490.0
HKD1_k127_4337276_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 429.0
HKD1_k127_4337276_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 425.0
HKD1_k127_4337276_7 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 413.0
HKD1_k127_4337276_8 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 389.0
HKD1_k127_4337276_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 377.0
HKD1_k127_433796_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.448e-246 776.0
HKD1_k127_4346301_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.976e-222 695.0
HKD1_k127_4346301_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 318.0
HKD1_k127_4346301_10 Tetratricopeptide repeat - - - 0.000000000006898 74.0
HKD1_k127_4346301_11 Domain of unknown function (DUF4418) - - - 0.000000002372 63.0
HKD1_k127_4346301_12 Putative heavy-metal-binding - - - 0.0001879 47.0
HKD1_k127_4346301_2 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 289.0
HKD1_k127_4346301_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005466 261.0
HKD1_k127_4346301_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 253.0
HKD1_k127_4346301_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001638 260.0
HKD1_k127_4346301_6 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000006844 206.0
HKD1_k127_4346301_7 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000002357 198.0
HKD1_k127_4346301_8 Stringent starvation protein B K09985 - - 0.00000000000000000000000000001872 123.0
HKD1_k127_4346301_9 NosL K19342 - - 0.00000000000007685 77.0
HKD1_k127_4387911_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 460.0
HKD1_k127_4387911_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 375.0
HKD1_k127_4387911_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 319.0
HKD1_k127_4388002_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
HKD1_k127_4388002_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 361.0
HKD1_k127_4388002_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
HKD1_k127_4388002_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007478 254.0
HKD1_k127_4388002_4 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.000000000000000000000000000000000000000000000000000000000007541 232.0
HKD1_k127_4388002_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000004539 129.0
HKD1_k127_4388002_6 - - - - 0.0000000000000000003146 91.0
HKD1_k127_4398390_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.616e-284 893.0
HKD1_k127_4398390_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 528.0
HKD1_k127_4398390_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 492.0
HKD1_k127_4398390_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 484.0
HKD1_k127_4398390_4 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 391.0
HKD1_k127_4398390_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 321.0
HKD1_k127_4398390_6 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009383 240.0
HKD1_k127_4398390_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000005901 209.0
HKD1_k127_4398390_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000002989 197.0
HKD1_k127_4398390_9 LuxR family transcriptional regulator - - - 0.000001029 57.0
HKD1_k127_4400684_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1566.0
HKD1_k127_4400684_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1069.0
HKD1_k127_4400684_10 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 481.0
HKD1_k127_4400684_11 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 479.0
HKD1_k127_4400684_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 457.0
HKD1_k127_4400684_13 Biotin-lipoyl like K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 440.0
HKD1_k127_4400684_14 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 428.0
HKD1_k127_4400684_15 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 420.0
HKD1_k127_4400684_16 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 396.0
HKD1_k127_4400684_17 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 346.0
HKD1_k127_4400684_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
HKD1_k127_4400684_19 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 345.0
HKD1_k127_4400684_2 Heat shock 70 kDa protein K04043 - - 0.0 1017.0
HKD1_k127_4400684_20 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 332.0
HKD1_k127_4400684_21 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
HKD1_k127_4400684_22 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 316.0
HKD1_k127_4400684_23 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
HKD1_k127_4400684_24 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 289.0
HKD1_k127_4400684_25 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005165 274.0
HKD1_k127_4400684_26 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003969 264.0
HKD1_k127_4400684_27 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000181 253.0
HKD1_k127_4400684_28 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HKD1_k127_4400684_29 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
HKD1_k127_4400684_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.873e-270 845.0
HKD1_k127_4400684_30 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002046 226.0
HKD1_k127_4400684_31 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000002055 236.0
HKD1_k127_4400684_32 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000001193 214.0
HKD1_k127_4400684_33 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000906 177.0
HKD1_k127_4400684_34 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000008336 164.0
HKD1_k127_4400684_35 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000003624 163.0
HKD1_k127_4400684_36 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000004988 144.0
HKD1_k127_4400684_37 - - - - 0.000000000000000000000000009457 119.0
HKD1_k127_4400684_38 Transcriptional regulator, LysR family K02019 - - 0.0000000000000000000000001608 118.0
HKD1_k127_4400684_39 iron-sulfur cluster assembly - - - 0.0000000000000000000000005632 105.0
HKD1_k127_4400684_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 4.369e-228 718.0
HKD1_k127_4400684_40 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000000000004002 108.0
HKD1_k127_4400684_41 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000004997 100.0
HKD1_k127_4400684_42 Cobalt transport protein K16785 - - 0.0000000000002391 80.0
HKD1_k127_4400684_43 STAS domain K04749 - - 0.0000000000008209 72.0
HKD1_k127_4400684_44 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000006576 63.0
HKD1_k127_4400684_45 - - - - 0.0000000002485 67.0
HKD1_k127_4400684_5 PFAM Polysulphide reductase, NrfD K00185 - - 6.585e-224 708.0
HKD1_k127_4400684_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 2.035e-203 639.0
HKD1_k127_4400684_7 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 558.0
HKD1_k127_4400684_8 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 524.0
HKD1_k127_4400684_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 492.0
HKD1_k127_4414213_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 378.0
HKD1_k127_4414213_1 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000003525 220.0
HKD1_k127_4414213_2 HupE / UreJ protein K03192 - - 0.00000000000000000000000000000000000000002843 156.0
HKD1_k127_4414213_3 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000004656 113.0
HKD1_k127_4414213_4 Tetratricopeptide repeat - - - 0.00000000000000000615 94.0
HKD1_k127_4414213_5 Cytochrome c K02305 - - 0.000000007498 62.0
HKD1_k127_4440212_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 516.0
HKD1_k127_4440212_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 491.0
HKD1_k127_4440212_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 495.0
HKD1_k127_4440212_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 415.0
HKD1_k127_4440212_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 335.0
HKD1_k127_4453859_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.261e-232 741.0
HKD1_k127_4453859_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 435.0
HKD1_k127_4453859_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 374.0
HKD1_k127_4453859_3 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 294.0
HKD1_k127_4453859_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000121 239.0
HKD1_k127_4453859_5 peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000001158 163.0
HKD1_k127_4453859_6 - - - - 0.0000000001812 70.0
HKD1_k127_4453859_7 - - - - 0.0003457 48.0
HKD1_k127_4464946_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.778e-201 646.0
HKD1_k127_4464946_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 512.0
HKD1_k127_4464946_10 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000008864 48.0
HKD1_k127_4464946_13 Peptidogalycan biosysnthesis/recognition - - - 0.0006909 51.0
HKD1_k127_4464946_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 440.0
HKD1_k127_4464946_3 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 418.0
HKD1_k127_4464946_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 261.0
HKD1_k127_4464946_5 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000527 227.0
HKD1_k127_4464946_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000007026 136.0
HKD1_k127_4464946_7 - - - - 0.0000000000000000000009378 100.0
HKD1_k127_4464946_8 Domain of unknown function (DUF1858) - - - 0.0000000000000000009377 89.0
HKD1_k127_4472419_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 469.0
HKD1_k127_4472419_1 cheY-homologous receiver domain - - - 0.0000000000000000000000004194 115.0
HKD1_k127_4472419_2 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000005986 93.0
HKD1_k127_4481049_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1034.0
HKD1_k127_4481049_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 513.0
HKD1_k127_4481049_2 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 508.0
HKD1_k127_4481049_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002773 276.0
HKD1_k127_4481049_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000009062 138.0
HKD1_k127_4481049_5 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000001919 126.0
HKD1_k127_4481049_6 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000196 110.0
HKD1_k127_4481049_7 - - - - 0.000000000002195 72.0
HKD1_k127_4481049_8 regulation of DNA repair K03565 - - 0.0000000000171 71.0
HKD1_k127_4513667_0 Sugar (and other) transporter K03446 - - 5.657e-246 767.0
HKD1_k127_4513667_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000001831 217.0
HKD1_k127_4513667_2 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000001506 163.0
HKD1_k127_4543826_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 7.535e-228 739.0
HKD1_k127_4543826_1 PFAM ABC transporter related K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 503.0
HKD1_k127_4543826_10 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000882 191.0
HKD1_k127_4543826_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000003129 169.0
HKD1_k127_4543826_12 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000006451 172.0
HKD1_k127_4543826_13 AMP binding - - - 0.0000000000000000000000000000000000000000003372 170.0
HKD1_k127_4543826_14 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000002568 144.0
HKD1_k127_4543826_15 Thiamine-binding protein - - - 0.00000000000000000000000000000000206 134.0
HKD1_k127_4543826_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000001159 122.0
HKD1_k127_4543826_17 Transposase domain (DUF772) - - - 0.000000000000000000000005396 106.0
HKD1_k127_4543826_18 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000001345 89.0
HKD1_k127_4543826_19 - - - - 0.000000000000000003471 87.0
HKD1_k127_4543826_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 465.0
HKD1_k127_4543826_20 Transposase DDE domain - - - 0.00000000001486 68.0
HKD1_k127_4543826_21 iron ion homeostasis - - - 0.000000001458 68.0
HKD1_k127_4543826_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 423.0
HKD1_k127_4543826_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 373.0
HKD1_k127_4543826_5 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 367.0
HKD1_k127_4543826_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 286.0
HKD1_k127_4543826_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003798 279.0
HKD1_k127_4543826_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004079 235.0
HKD1_k127_4543826_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
HKD1_k127_4558937_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 541.0
HKD1_k127_4558937_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 524.0
HKD1_k127_4558937_10 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000001983 156.0
HKD1_k127_4558937_11 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000557 89.0
HKD1_k127_4558937_13 - - - - 0.00005305 49.0
HKD1_k127_4558937_2 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 507.0
HKD1_k127_4558937_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 488.0
HKD1_k127_4558937_4 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 443.0
HKD1_k127_4558937_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 418.0
HKD1_k127_4558937_6 sulfate ABC transporter, permease protein CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 396.0
HKD1_k127_4558937_7 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 382.0
HKD1_k127_4558937_8 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000003024 249.0
HKD1_k127_4558937_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000001464 236.0
HKD1_k127_4564024_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 2.427e-221 696.0
HKD1_k127_4564024_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 552.0
HKD1_k127_4564024_2 lipoprotein localization to outer membrane K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 405.0
HKD1_k127_4564024_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HKD1_k127_4564024_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 298.0
HKD1_k127_4564024_5 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000006105 132.0
HKD1_k127_4568993_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1074.0
HKD1_k127_4568993_1 Elongation factor G, domain IV K02355 - - 2.48e-306 951.0
HKD1_k127_4568993_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002708 271.0
HKD1_k127_4581893_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 352.0
HKD1_k127_4581893_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000008858 220.0
HKD1_k127_4581893_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000271 201.0
HKD1_k127_4581893_3 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000001871 179.0
HKD1_k127_4581893_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000002451 147.0
HKD1_k127_4581893_6 iron ion binding - - - 0.000000000000000000000000000000004547 138.0
HKD1_k127_4585539_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 569.0
HKD1_k127_4585539_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 449.0
HKD1_k127_4585539_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000008251 193.0
HKD1_k127_4585539_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001872 143.0
HKD1_k127_4585539_12 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000000009465 135.0
HKD1_k127_4585539_13 - - - - 0.0000000000000000000000000000005217 127.0
HKD1_k127_4585539_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000003247 80.0
HKD1_k127_4585539_15 cheY-homologous receiver domain - - - 0.000001435 54.0
HKD1_k127_4585539_2 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 406.0
HKD1_k127_4585539_3 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
HKD1_k127_4585539_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
HKD1_k127_4585539_5 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HKD1_k127_4585539_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006283 267.0
HKD1_k127_4585539_7 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000001471 206.0
HKD1_k127_4585539_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000162 201.0
HKD1_k127_4585539_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000008576 194.0
HKD1_k127_4607312_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.084e-292 909.0
HKD1_k127_4607312_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000006516 120.0
HKD1_k127_46648_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.0 1069.0
HKD1_k127_46648_1 GTP-binding protein TypA K06207 - - 2.046e-267 836.0
HKD1_k127_46648_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
HKD1_k127_46648_11 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002343 274.0
HKD1_k127_46648_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004253 255.0
HKD1_k127_46648_13 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009934 250.0
HKD1_k127_46648_14 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001083 239.0
HKD1_k127_46648_15 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
HKD1_k127_46648_16 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 231.0
HKD1_k127_46648_17 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
HKD1_k127_46648_18 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000004322 211.0
HKD1_k127_46648_19 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000002903 185.0
HKD1_k127_46648_2 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 3.029e-224 717.0
HKD1_k127_46648_20 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000000000000005386 198.0
HKD1_k127_46648_21 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000005699 178.0
HKD1_k127_46648_22 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000001443 158.0
HKD1_k127_46648_23 - - - - 0.0000000000000261 74.0
HKD1_k127_46648_24 nuclear chromosome segregation - - - 0.000000006188 65.0
HKD1_k127_46648_3 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 572.0
HKD1_k127_46648_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 454.0
HKD1_k127_46648_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 456.0
HKD1_k127_46648_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 451.0
HKD1_k127_46648_7 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 437.0
HKD1_k127_46648_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 418.0
HKD1_k127_46648_9 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 340.0
HKD1_k127_4730627_0 outer membrane efflux - - - 9.735e-199 632.0
HKD1_k127_4730627_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 537.0
HKD1_k127_4730627_10 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000001309 192.0
HKD1_k127_4730627_11 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000001627 124.0
HKD1_k127_4730627_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 511.0
HKD1_k127_4730627_3 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 485.0
HKD1_k127_4730627_4 (ABC) transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 428.0
HKD1_k127_4730627_5 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 419.0
HKD1_k127_4730627_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 415.0
HKD1_k127_4730627_7 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
HKD1_k127_4730627_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 269.0
HKD1_k127_4730627_9 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004771 237.0
HKD1_k127_4743245_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 2.207e-218 688.0
HKD1_k127_4743245_1 Aminotransferase class-III K01845 - 5.4.3.8 1.431e-201 636.0
HKD1_k127_4743245_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 410.0
HKD1_k127_4743245_11 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 369.0
HKD1_k127_4743245_12 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 370.0
HKD1_k127_4743245_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 362.0
HKD1_k127_4743245_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
HKD1_k127_4743245_15 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 334.0
HKD1_k127_4743245_16 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 327.0
HKD1_k127_4743245_17 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001228 281.0
HKD1_k127_4743245_18 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002196 273.0
HKD1_k127_4743245_19 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009774 250.0
HKD1_k127_4743245_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 610.0
HKD1_k127_4743245_20 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000005586 239.0
HKD1_k127_4743245_21 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
HKD1_k127_4743245_22 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000002018 224.0
HKD1_k127_4743245_23 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000008424 220.0
HKD1_k127_4743245_24 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000003827 221.0
HKD1_k127_4743245_25 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001108 205.0
HKD1_k127_4743245_26 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000000000003534 205.0
HKD1_k127_4743245_27 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000007058 182.0
HKD1_k127_4743245_28 Transcriptional regulator - - - 0.00000000000000000000000000000000000000003896 160.0
HKD1_k127_4743245_29 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000008747 154.0
HKD1_k127_4743245_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 526.0
HKD1_k127_4743245_30 heat shock protein binding - - - 0.00000000000000000000000000000000000009822 154.0
HKD1_k127_4743245_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000000728 142.0
HKD1_k127_4743245_32 protein complex oligomerization - - - 0.000000000000000000000000000003175 126.0
HKD1_k127_4743245_33 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000001134 117.0
HKD1_k127_4743245_34 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000003766 78.0
HKD1_k127_4743245_35 - - - - 0.0000000003906 71.0
HKD1_k127_4743245_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 515.0
HKD1_k127_4743245_5 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 453.0
HKD1_k127_4743245_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 434.0
HKD1_k127_4743245_7 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
HKD1_k127_4743245_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 429.0
HKD1_k127_4743245_9 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 415.0
HKD1_k127_4815923_0 SMART Elongator protein 3 MiaB NifB - - - 5.502e-216 679.0
HKD1_k127_4815923_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
HKD1_k127_4815923_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 267.0
HKD1_k127_4815923_3 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002356 259.0
HKD1_k127_4815923_4 PFAM PHP domain - - - 0.00000000000000000000000000000000000000127 156.0
HKD1_k127_4815923_5 - - - - 0.0000000002027 68.0
HKD1_k127_4936350_0 alpha amylase, catalytic K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
HKD1_k127_4936350_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 337.0
HKD1_k127_4963_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 341.0
HKD1_k127_4963_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 309.0
HKD1_k127_4963_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000004319 228.0
HKD1_k127_4963_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000013 175.0
HKD1_k127_4963_4 Universal stress protein family - - - 0.0000000000000000000000000000000000001366 146.0
HKD1_k127_4963_5 proteolysis K03665 - - 0.00000000000000000000000000001124 124.0
HKD1_k127_4977722_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1251.0
HKD1_k127_4977722_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 556.0
HKD1_k127_4977722_10 CARDB domain-containing protein,subtilase family protease - - - 0.0000000000000000004391 102.0
HKD1_k127_4977722_11 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000008895 83.0
HKD1_k127_4977722_2 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 515.0
HKD1_k127_4977722_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 470.0
HKD1_k127_4977722_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 336.0
HKD1_k127_4977722_5 cellulose binding K15924 - 3.2.1.136 0.000000000000000000000000000000000000000000000000000000000001697 229.0
HKD1_k127_4977722_6 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000006227 180.0
HKD1_k127_4977722_7 AI-2E family transporter - - - 0.0000000000000000000000000000000453 139.0
HKD1_k127_4977722_8 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000005831 122.0
HKD1_k127_4977722_9 - - - - 0.00000000000000000003978 98.0
HKD1_k127_5029605_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1298.0
HKD1_k127_5029605_1 Formate dehydrogenase N, transmembrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 463.0
HKD1_k127_5029605_10 - - - - 0.000000001142 65.0
HKD1_k127_5029605_11 integral membrane protein - - - 0.0004646 47.0
HKD1_k127_5029605_2 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 389.0
HKD1_k127_5029605_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 317.0
HKD1_k127_5029605_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 306.0
HKD1_k127_5029605_5 TIGRFAM Formate dehydrogenase, gamma subunit K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000982 257.0
HKD1_k127_5029605_6 Necessary for formate dehydrogenase activity K02380 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000005611 235.0
HKD1_k127_5029605_7 Lipocalin-like domain - - - 0.0000000000000000000000000000001054 124.0
HKD1_k127_5029605_8 Lipocalin-like domain - - - 0.00000000000000000000002393 102.0
HKD1_k127_5029605_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000001053 61.0
HKD1_k127_5030400_0 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 557.0
HKD1_k127_5030400_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 456.0
HKD1_k127_5030400_2 ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000361 289.0
HKD1_k127_5030400_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000003706 209.0
HKD1_k127_5030400_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002328 166.0
HKD1_k127_5030400_5 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000003421 158.0
HKD1_k127_5030400_6 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000007418 156.0
HKD1_k127_5030400_7 - - - - 0.000308 49.0
HKD1_k127_5030400_8 Response regulator, receiver - - - 0.0003445 51.0
HKD1_k127_5055357_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 8.756e-274 854.0
HKD1_k127_5055357_1 ABC transporter K06158 - - 3.76e-222 704.0
HKD1_k127_5055357_10 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 479.0
HKD1_k127_5055357_11 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 438.0
HKD1_k127_5055357_12 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 426.0
HKD1_k127_5055357_13 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 395.0
HKD1_k127_5055357_14 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 386.0
HKD1_k127_5055357_15 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
HKD1_k127_5055357_16 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 334.0
HKD1_k127_5055357_17 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 299.0
HKD1_k127_5055357_18 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
HKD1_k127_5055357_19 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006862 276.0
HKD1_k127_5055357_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.073e-219 692.0
HKD1_k127_5055357_20 PFAM Sulphate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004296 278.0
HKD1_k127_5055357_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
HKD1_k127_5055357_22 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000009976 211.0
HKD1_k127_5055357_23 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000002033 209.0
HKD1_k127_5055357_24 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000003267 204.0
HKD1_k127_5055357_25 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000004449 196.0
HKD1_k127_5055357_26 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000489 192.0
HKD1_k127_5055357_27 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000003819 167.0
HKD1_k127_5055357_28 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000002171 159.0
HKD1_k127_5055357_29 SMART Cold shock protein K03704 - - 0.000000000000000000000000004803 110.0
HKD1_k127_5055357_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.177e-199 625.0
HKD1_k127_5055357_30 ACT domain protein - - - 0.0000000000000006226 83.0
HKD1_k127_5055357_31 thiamine diphosphate biosynthetic process K03154 - - 0.000000000000004717 78.0
HKD1_k127_5055357_32 - - - - 0.000000000000006979 80.0
HKD1_k127_5055357_33 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000008635 71.0
HKD1_k127_5055357_35 Zinc dependent phospholipase C - - - 0.000000006268 62.0
HKD1_k127_5055357_36 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0003797 46.0
HKD1_k127_5055357_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 591.0
HKD1_k127_5055357_5 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 548.0
HKD1_k127_5055357_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 540.0
HKD1_k127_5055357_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 522.0
HKD1_k127_5055357_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 493.0
HKD1_k127_5055357_9 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 481.0
HKD1_k127_5065646_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.766e-207 657.0
HKD1_k127_5065646_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 473.0
HKD1_k127_5065646_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 301.0
HKD1_k127_5065646_3 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 309.0
HKD1_k127_5065646_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.00000000000000000000000000505 110.0
HKD1_k127_5065646_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000001824 116.0
HKD1_k127_5065646_6 radical SAM domain protein - - - 0.0000000000000000000004581 108.0
HKD1_k127_5085862_0 Dehydratase family K01687 - 4.2.1.9 1.362e-261 813.0
HKD1_k127_5085862_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.692e-238 742.0
HKD1_k127_5086900_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1423.0
HKD1_k127_5086900_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1236.0
HKD1_k127_5086900_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 303.0
HKD1_k127_5086900_11 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000528 273.0
HKD1_k127_5086900_12 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
HKD1_k127_5086900_13 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000579 236.0
HKD1_k127_5086900_14 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000002773 225.0
HKD1_k127_5086900_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000006551 184.0
HKD1_k127_5086900_16 PFAM ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000001057 175.0
HKD1_k127_5086900_17 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000588 169.0
HKD1_k127_5086900_18 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000008654 151.0
HKD1_k127_5086900_2 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1043.0
HKD1_k127_5086900_20 Transcriptional regulator K02529 - - 0.00000000000000009347 87.0
HKD1_k127_5086900_21 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000002067 66.0
HKD1_k127_5086900_3 Phosphoglucose isomerase K01810 - 5.3.1.9 6.448e-296 914.0
HKD1_k127_5086900_4 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 9.057e-224 701.0
HKD1_k127_5086900_5 GatB domain K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 4.044e-197 626.0
HKD1_k127_5086900_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 596.0
HKD1_k127_5086900_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 529.0
HKD1_k127_5086900_8 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 530.0
HKD1_k127_5086900_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 319.0
HKD1_k127_5090690_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 431.0
HKD1_k127_5090690_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 356.0
HKD1_k127_5090690_2 Cytochrome c554 and c-prime - - - 0.000000000000000000003441 100.0
HKD1_k127_5090690_3 Class III cytochrome C family - - - 0.000000000000001626 83.0
HKD1_k127_5095008_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.889e-242 757.0
HKD1_k127_5095008_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.977e-236 740.0
HKD1_k127_5095008_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.842e-235 746.0
HKD1_k127_5095008_3 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 452.0
HKD1_k127_5095008_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 315.0
HKD1_k127_5095008_5 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
HKD1_k127_5095008_6 - - - - 0.00000000000000000000000000000000000000000000000000000000573 205.0
HKD1_k127_5095008_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000006671 127.0
HKD1_k127_5095008_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000009521 103.0
HKD1_k127_5114428_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 351.0
HKD1_k127_5114428_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 290.0
HKD1_k127_5119466_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.434e-285 882.0
HKD1_k127_5119466_1 Titin-like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0001126 54.0
HKD1_k127_5132233_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 445.0
HKD1_k127_5132233_1 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 345.0
HKD1_k127_5132233_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000386 209.0
HKD1_k127_5132233_3 Domain of Unknown Function (DUF350) K08989 - - 0.000000000000000000000000000000001297 134.0
HKD1_k127_5139189_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 385.0
HKD1_k127_5139189_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 254.0
HKD1_k127_5141107_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1092.0
HKD1_k127_5141107_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.095e-240 753.0
HKD1_k127_5141107_12 CHASE K02488,K21009 - 2.7.7.65 0.000006607 51.0
HKD1_k127_5141107_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 389.0
HKD1_k127_5141107_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 305.0
HKD1_k127_5141107_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002509 291.0
HKD1_k127_5141107_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
HKD1_k127_5141107_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000001362 220.0
HKD1_k127_5141107_7 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000000000001139 195.0
HKD1_k127_5141107_8 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000006045 186.0
HKD1_k127_5141107_9 response regulator - - - 0.0000000000000000000000000000000000003554 153.0
HKD1_k127_5150816_0 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 481.0
HKD1_k127_5150816_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 454.0
HKD1_k127_5150816_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 366.0
HKD1_k127_5150816_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HKD1_k127_5150816_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003355 283.0
HKD1_k127_5150816_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000009456 220.0
HKD1_k127_5150816_6 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000002077 191.0
HKD1_k127_5150816_7 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000005149 151.0
HKD1_k127_5150816_8 electron transfer activity K05337,K17247 - - 0.000000000000000000000000000002154 120.0
HKD1_k127_5150816_9 Cupin 2, conserved barrel domain protein - - - 0.00000000002551 68.0
HKD1_k127_5154326_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.226e-273 858.0
HKD1_k127_5154326_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.808e-233 727.0
HKD1_k127_5154326_10 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000006659 190.0
HKD1_k127_5154326_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000001498 121.0
HKD1_k127_5154326_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000004311 111.0
HKD1_k127_5154326_13 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000003239 83.0
HKD1_k127_5154326_14 AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000226 78.0
HKD1_k127_5154326_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.205e-198 625.0
HKD1_k127_5154326_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 612.0
HKD1_k127_5154326_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 468.0
HKD1_k127_5154326_5 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 467.0
HKD1_k127_5154326_6 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 398.0
HKD1_k127_5154326_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007041 268.0
HKD1_k127_5154326_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003516 264.0
HKD1_k127_5154326_9 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002302 238.0
HKD1_k127_5160427_0 Domain of unknown function (DUF4139) - - - 1.593e-203 644.0
HKD1_k127_5160427_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 599.0
HKD1_k127_5160427_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000435 261.0
HKD1_k127_5160427_3 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 248.0
HKD1_k127_5160427_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000001671 215.0
HKD1_k127_5160427_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000001941 206.0
HKD1_k127_5160427_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000001293 122.0
HKD1_k127_5160427_7 Putative zinc-finger - - - 0.0000000000000000000000001053 118.0
HKD1_k127_5161926_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.801e-245 773.0
HKD1_k127_5161926_1 NMT1-like family K02051 - - 0.000000000000000000000000000007313 123.0
HKD1_k127_5161926_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000008505 77.0
HKD1_k127_5186571_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 314.0
HKD1_k127_5186571_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000001367 136.0
HKD1_k127_5201611_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 394.0
HKD1_k127_5201611_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000004808 196.0
HKD1_k127_5201611_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000003548 140.0
HKD1_k127_5205723_0 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 307.0
HKD1_k127_5205723_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001012 303.0
HKD1_k127_5205723_2 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.0000000000000000000000000000000000000000000001924 177.0
HKD1_k127_5205723_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000002824 151.0
HKD1_k127_5205723_4 transferase activity, transferring acyl groups - - - 0.000000000000000000000000001445 130.0
HKD1_k127_5210365_0 Belongs to the ClpA ClpB family K03694 - - 4.546e-278 874.0
HKD1_k127_5210365_1 4Fe-4S binding domain - - - 5.835e-220 692.0
HKD1_k127_5210365_10 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003053 254.0
HKD1_k127_5210365_11 SMART Signal transduction response regulator, receiver region - - - 0.0000000000000000000000000000000000000000000000000000000000001465 214.0
HKD1_k127_5210365_12 protein histidine kinase activity K19616,K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001321 223.0
HKD1_k127_5210365_13 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000001768 161.0
HKD1_k127_5210365_14 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000003878 140.0
HKD1_k127_5210365_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000009998 126.0
HKD1_k127_5210365_16 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000004815 81.0
HKD1_k127_5210365_17 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000007626 59.0
HKD1_k127_5210365_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 409.0
HKD1_k127_5210365_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 369.0
HKD1_k127_5210365_4 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 379.0
HKD1_k127_5210365_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 308.0
HKD1_k127_5210365_6 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 312.0
HKD1_k127_5210365_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 293.0
HKD1_k127_5210365_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 296.0
HKD1_k127_5210365_9 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 279.0
HKD1_k127_5221475_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1066.0
HKD1_k127_5221475_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 576.0
HKD1_k127_5221475_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 555.0
HKD1_k127_5221475_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 483.0
HKD1_k127_5221475_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 432.0
HKD1_k127_5221475_5 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 416.0
HKD1_k127_5221475_6 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004077 276.0
HKD1_k127_5221475_7 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002105 270.0
HKD1_k127_5223663_0 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000002827 231.0
HKD1_k127_5223663_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00004487 45.0
HKD1_k127_5234692_0 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000002729 212.0
HKD1_k127_5234692_1 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000001387 209.0
HKD1_k127_5234692_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000005594 174.0
HKD1_k127_5243654_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1558.0
HKD1_k127_5243654_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 558.0
HKD1_k127_5243654_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 456.0
HKD1_k127_5243654_3 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 432.0
HKD1_k127_5243654_4 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000007351 135.0
HKD1_k127_5264702_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.85e-310 962.0
HKD1_k127_5264702_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 459.0
HKD1_k127_5264702_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 341.0
HKD1_k127_5264702_3 PFAM NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
HKD1_k127_5264702_4 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001235 243.0
HKD1_k127_5264702_5 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000004432 192.0
HKD1_k127_5264702_6 HAF family - - - 0.00000000000000000000000000000000000000000001814 168.0
HKD1_k127_5264702_7 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000002308 130.0
HKD1_k127_5264702_8 - - - - 0.0000000000000001729 88.0
HKD1_k127_5277753_0 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003045 253.0
HKD1_k127_5277753_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000629 197.0
HKD1_k127_5277753_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000003133 102.0
HKD1_k127_5277753_3 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000002437 97.0
HKD1_k127_5277753_4 PFAM DsrE family protein K07235 - - 0.000000001693 66.0
HKD1_k127_5277753_5 Tetratricopeptide repeat protein - - - 0.000002005 58.0
HKD1_k127_5277753_6 PFAM DsrE K07235 - - 0.0002881 46.0
HKD1_k127_5277753_7 Domains LysM, LysM, NLPC_P60 K19223 - - 0.0006895 47.0
HKD1_k127_5278520_0 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009332 259.0
HKD1_k127_5278520_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000002217 199.0
HKD1_k127_5278520_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000004132 189.0
HKD1_k127_5278520_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000004858 183.0
HKD1_k127_5278520_4 - - - - 0.0000000000000000000000000000000000004154 141.0
HKD1_k127_5278520_5 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000004086 127.0
HKD1_k127_5278520_6 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000002438 97.0
HKD1_k127_5278520_7 - - - - 0.000000000000000000001532 98.0
HKD1_k127_5278520_8 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000007615 92.0
HKD1_k127_5283238_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1093.0
HKD1_k127_5283238_1 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 513.0
HKD1_k127_5283238_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005224 241.0
HKD1_k127_5283238_3 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000001982 162.0
HKD1_k127_5283238_4 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0001023 50.0
HKD1_k127_5299320_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1041.0
HKD1_k127_5299320_1 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003629 273.0
HKD1_k127_5299320_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein K16885 - - 0.000000000000000000000000000000000000000002472 159.0
HKD1_k127_5311045_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 470.0
HKD1_k127_5311045_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 375.0
HKD1_k127_5311045_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000008892 177.0
HKD1_k127_5317379_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 574.0
HKD1_k127_5317379_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 448.0
HKD1_k127_5317379_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 425.0
HKD1_k127_5317379_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 418.0
HKD1_k127_5317379_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 342.0
HKD1_k127_5317379_5 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000003873 173.0
HKD1_k127_5317379_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000003202 162.0
HKD1_k127_5317379_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000002219 126.0
HKD1_k127_5317379_8 Belongs to the universal stress protein A family - - - 0.00000003288 61.0
HKD1_k127_5338029_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 564.0
HKD1_k127_5338029_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 464.0
HKD1_k127_5338029_10 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000001219 93.0
HKD1_k127_5338029_11 Sulfur relay protein TusC DsrF K07236 - - 0.000000006268 62.0
HKD1_k127_5338029_12 Transcriptional regulators - - - 0.0000001449 55.0
HKD1_k127_5338029_13 PFAM DsrE K07235 - - 0.00001893 50.0
HKD1_k127_5338029_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 392.0
HKD1_k127_5338029_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001192 283.0
HKD1_k127_5338029_4 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004674 258.0
HKD1_k127_5338029_5 Diguanylate cyclase phosphodiesterase (GGDEF EAL domains) with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000002679 236.0
HKD1_k127_5338029_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000001574 198.0
HKD1_k127_5338029_7 - - - - 0.0000000000000000000000006435 106.0
HKD1_k127_5338029_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000001104 106.0
HKD1_k127_5338029_9 Tetratricopeptide repeat-like domain - - - 0.000000000000000000004189 102.0
HKD1_k127_5341709_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 8.697e-246 782.0
HKD1_k127_5341709_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 567.0
HKD1_k127_5341709_10 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000000815 78.0
HKD1_k127_5341709_11 FixH - - - 0.000000000001381 73.0
HKD1_k127_5341709_12 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000001714 68.0
HKD1_k127_5341709_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 465.0
HKD1_k127_5341709_3 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
HKD1_k127_5341709_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 329.0
HKD1_k127_5341709_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000003227 211.0
HKD1_k127_5341709_6 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000000000000000003297 161.0
HKD1_k127_5341709_7 HD domain - - - 0.000000000000000000000000000003086 123.0
HKD1_k127_5341709_8 - - - - 0.00000000000000000000000004663 113.0
HKD1_k127_5341709_9 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.0000000000000000000001574 100.0
HKD1_k127_5355121_0 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 421.0
HKD1_k127_5355121_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 406.0
HKD1_k127_5355121_10 Protein of unknown function (DUF1264) - - - 0.00000000000002504 81.0
HKD1_k127_5355121_11 Methylmuconolactone methyl-isomerase - - - 0.00000000000003386 77.0
HKD1_k127_5355121_12 PFAM Lytic transglycosylase catalytic - - - 0.00000003111 63.0
HKD1_k127_5355121_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
HKD1_k127_5355121_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 290.0
HKD1_k127_5355121_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000983 275.0
HKD1_k127_5355121_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000007947 190.0
HKD1_k127_5355121_6 VanZ like family - - - 0.00000000000000000000000000000000000000000000001332 176.0
HKD1_k127_5355121_7 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000001542 164.0
HKD1_k127_5355121_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000541 157.0
HKD1_k127_5355121_9 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000004983 140.0
HKD1_k127_5365809_0 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 3.915e-197 618.0
HKD1_k127_5365809_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 511.0
HKD1_k127_5365809_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 494.0
HKD1_k127_5365809_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000004433 183.0
HKD1_k127_5365809_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000000002967 177.0
HKD1_k127_5365809_5 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000004201 150.0
HKD1_k127_5365809_6 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000113 111.0
HKD1_k127_5365809_7 lyase activity - - - 0.00000000000000001974 86.0
HKD1_k127_5373224_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000004098 209.0
HKD1_k127_5373224_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000001818 104.0
HKD1_k127_5384159_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001335 237.0
HKD1_k127_5384159_1 regulation of ruffle assembly - - - 0.00000000000000000000000000000000000000000000000000000000001577 214.0
HKD1_k127_5384159_2 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000001629 154.0
HKD1_k127_5384159_3 HNH nucleases - - - 0.00000000000000000000000000000000000001564 146.0
HKD1_k127_5384159_4 Protein of unknown function (DUF507) - - - 0.00000000000000000000000002545 112.0
HKD1_k127_5384159_5 Protein of unknown function (DUF507) - - - 0.00000000000002978 73.0
HKD1_k127_5384159_6 - - - - 0.000000007903 65.0
HKD1_k127_5385714_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 456.0
HKD1_k127_5385714_1 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
HKD1_k127_5385714_2 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000004616 230.0
HKD1_k127_5385714_3 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000001016 146.0
HKD1_k127_5385714_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001082 68.0
HKD1_k127_5385714_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00003916 48.0
HKD1_k127_5391391_0 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 429.0
HKD1_k127_5391391_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 382.0
HKD1_k127_5391391_10 - - - - 0.0000000000000007926 84.0
HKD1_k127_5391391_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000001565 73.0
HKD1_k127_5391391_13 Major Facilitator Superfamily K08224 - - 0.00004567 47.0
HKD1_k127_5391391_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 372.0
HKD1_k127_5391391_3 Major Facilitator Superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
HKD1_k127_5391391_4 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
HKD1_k127_5391391_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001763 218.0
HKD1_k127_5391391_6 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000004925 198.0
HKD1_k127_5391391_7 Major Facilitator Superfamily K08224 - - 0.00000000000000000000000000000000000000000000000414 176.0
HKD1_k127_5391391_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000002095 159.0
HKD1_k127_5391391_9 PFAM histidine kinase, HAMP region domain protein - - - 0.000000000000000000003298 99.0
HKD1_k127_5391542_0 Ftsk_gamma K03466 - - 2.802e-195 631.0
HKD1_k127_5391542_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 578.0
HKD1_k127_5391542_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 429.0
HKD1_k127_5391542_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000006263 227.0
HKD1_k127_5391542_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000003054 147.0
HKD1_k127_5391542_5 peptidase U32 - - - 0.00000000000000000002507 94.0
HKD1_k127_5391542_7 - - - - 0.00000002322 58.0
HKD1_k127_5464340_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 536.0
HKD1_k127_5464340_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 395.0
HKD1_k127_5464340_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 333.0
HKD1_k127_5464340_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003829 244.0
HKD1_k127_5470317_0 FAD binding domain K00278 - 1.4.3.16 2.636e-199 639.0
HKD1_k127_5470317_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 580.0
HKD1_k127_5470317_10 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 444.0
HKD1_k127_5470317_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 431.0
HKD1_k127_5470317_12 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 417.0
HKD1_k127_5470317_13 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 393.0
HKD1_k127_5470317_14 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 339.0
HKD1_k127_5470317_15 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 264.0
HKD1_k127_5470317_16 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000002735 222.0
HKD1_k127_5470317_17 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000007615 200.0
HKD1_k127_5470317_18 - - - - 0.000000000000000000000000000000000000000000000004689 179.0
HKD1_k127_5470317_19 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000005232 195.0
HKD1_k127_5470317_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 584.0
HKD1_k127_5470317_20 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000001825 130.0
HKD1_k127_5470317_21 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000003027 118.0
HKD1_k127_5470317_23 RDD family - - - 0.0000000000000000000000002507 110.0
HKD1_k127_5470317_24 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000002607 101.0
HKD1_k127_5470317_25 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.00000000000000000000003019 110.0
HKD1_k127_5470317_26 endonuclease containing a URI domain K07461 - - 0.000000000000000000001456 97.0
HKD1_k127_5470317_27 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000007222 103.0
HKD1_k127_5470317_28 Lipocalin-like domain K03098 - - 0.000000000000003438 78.0
HKD1_k127_5470317_3 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 544.0
HKD1_k127_5470317_30 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.00000000001734 65.0
HKD1_k127_5470317_31 Heavy-metal-associated domain K01534 - 3.6.3.3,3.6.3.5 0.0000003245 57.0
HKD1_k127_5470317_32 Parallel beta-helix repeats - - - 0.00001032 59.0
HKD1_k127_5470317_33 rod shape-determining protein MreD K03571 - - 0.000154 50.0
HKD1_k127_5470317_4 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 546.0
HKD1_k127_5470317_6 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 537.0
HKD1_k127_5470317_7 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 450.0
HKD1_k127_5470317_8 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
HKD1_k127_5470317_9 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 428.0
HKD1_k127_5470837_0 Peptidase family M28 - - - 0.0 1129.0
HKD1_k127_5470837_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 474.0
HKD1_k127_5470837_2 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004263 277.0
HKD1_k127_5470837_3 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000001254 142.0
HKD1_k127_5470837_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000001263 119.0
HKD1_k127_5470837_6 Domain of unknown function (DUF4382) - - - 0.00000000000005123 82.0
HKD1_k127_5470837_7 to Saccharomyces cerevisiae JEM1 (YJL073W) K09523 GO:0000003,GO:0000741,GO:0000742,GO:0000746,GO:0000747,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0006997,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016043,GO:0019538,GO:0019941,GO:0019953,GO:0022414,GO:0030163,GO:0030433,GO:0033554,GO:0034975,GO:0034976,GO:0036503,GO:0042175,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044764,GO:0048284,GO:0050896,GO:0051082,GO:0051087,GO:0051603,GO:0051704,GO:0051716,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.00000001444 68.0
HKD1_k127_5560629_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 615.0
HKD1_k127_5560629_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 467.0
HKD1_k127_5560629_10 -O-antigen K16705 - - 0.0000000000000000000000000000003237 128.0
HKD1_k127_5560629_11 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000005627 102.0
HKD1_k127_5560629_12 S-layer homology domain - - - 0.000000000000000002811 100.0
HKD1_k127_5560629_14 - - - - 0.0000000003726 66.0
HKD1_k127_5560629_2 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 367.0
HKD1_k127_5560629_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 321.0
HKD1_k127_5560629_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 311.0
HKD1_k127_5560629_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 304.0
HKD1_k127_5560629_6 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005303 254.0
HKD1_k127_5560629_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000001817 214.0
HKD1_k127_5560629_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000003256 215.0
HKD1_k127_5560629_9 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000001783 196.0
HKD1_k127_556125_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 2.002e-218 688.0
HKD1_k127_556125_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 480.0
HKD1_k127_556125_10 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000004049 201.0
HKD1_k127_556125_11 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000009907 173.0
HKD1_k127_556125_12 - - - - 0.00000000000000000000000000000000000001425 146.0
HKD1_k127_556125_13 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000000000001252 149.0
HKD1_k127_556125_14 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000000000000000000001835 141.0
HKD1_k127_556125_15 UTRA K03710 - - 0.000000000000000000000000000000000681 140.0
HKD1_k127_556125_16 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000001643 120.0
HKD1_k127_556125_17 - - - - 0.0000000000000000000000000001886 115.0
HKD1_k127_556125_18 Phospholipid methyltransferase - - - 0.0000000000000000000082 100.0
HKD1_k127_556125_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 468.0
HKD1_k127_556125_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 463.0
HKD1_k127_556125_4 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 412.0
HKD1_k127_556125_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 392.0
HKD1_k127_556125_6 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
HKD1_k127_556125_7 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 291.0
HKD1_k127_556125_8 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007709 295.0
HKD1_k127_556125_9 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 269.0
HKD1_k127_5568386_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005778 270.0
HKD1_k127_5568386_1 pfam psp1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004303 252.0
HKD1_k127_5568386_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000003355 162.0
HKD1_k127_5632842_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.871e-260 818.0
HKD1_k127_5632842_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.349e-223 708.0
HKD1_k127_5632842_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001712 113.0
HKD1_k127_5632842_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000007035 78.0
HKD1_k127_5632842_4 Aspartate decarboxylase K01579 - 4.1.1.11 0.0000005513 51.0
HKD1_k127_5683069_0 domain, Protein K12373 - 3.2.1.52 0.0 1219.0
HKD1_k127_5683069_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000553 230.0
HKD1_k127_5683069_2 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000000000000000000000000002986 202.0
HKD1_k127_5683069_3 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000003593 172.0
HKD1_k127_5729276_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1253.0
HKD1_k127_5729276_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 268.0
HKD1_k127_5729276_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000001532 208.0
HKD1_k127_5729276_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000001561 184.0
HKD1_k127_5729276_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000007018 154.0
HKD1_k127_5729276_5 heat shock protein binding - - - 0.0000000000000000000000000000000000002028 153.0
HKD1_k127_5729276_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000002346 139.0
HKD1_k127_5777757_0 Nickel-dependent hydrogenase - - - 9.754e-201 636.0
HKD1_k127_5777757_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 8.887e-194 617.0
HKD1_k127_5777757_10 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
HKD1_k127_5777757_11 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 299.0
HKD1_k127_5777757_12 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000006731 229.0
HKD1_k127_5777757_13 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
HKD1_k127_5777757_14 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
HKD1_k127_5777757_15 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000001035 220.0
HKD1_k127_5777757_16 SMART Signal transduction response regulator, receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000006562 214.0
HKD1_k127_5777757_17 - - - - 0.00000000000000000000000000000000000000000000000001148 186.0
HKD1_k127_5777757_18 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.0000000000000000000000000000000000000000000000001377 184.0
HKD1_k127_5777757_19 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000000000001669 171.0
HKD1_k127_5777757_2 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 599.0
HKD1_k127_5777757_20 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000295 151.0
HKD1_k127_5777757_21 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.00000000000000000000000000000000001119 140.0
HKD1_k127_5777757_24 Alanine-zipper, major outer membrane lipoprotein - - - 0.000000001039 63.0
HKD1_k127_5777757_3 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 429.0
HKD1_k127_5777757_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 394.0
HKD1_k127_5777757_5 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 380.0
HKD1_k127_5777757_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 369.0
HKD1_k127_5777757_7 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 342.0
HKD1_k127_5777757_8 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 327.0
HKD1_k127_5777757_9 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 334.0
HKD1_k127_579931_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 566.0
HKD1_k127_579931_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000001597 175.0
HKD1_k127_579931_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000004889 168.0
HKD1_k127_579931_3 - - - - 0.00000000000000001577 88.0
HKD1_k127_6037957_0 Protein of unknown function, DUF255 K06888 - - 8.24e-206 652.0
HKD1_k127_6037957_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000009464 220.0
HKD1_k127_6047139_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1109.0
HKD1_k127_6051944_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.217e-254 809.0
HKD1_k127_6051944_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 475.0
HKD1_k127_6051944_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000006491 141.0
HKD1_k127_6051944_3 - - - - 0.000000000000000000148 100.0
HKD1_k127_6051944_4 DsrE/DsrF-like family - - - 0.0000228 50.0
HKD1_k127_6072161_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 464.0
HKD1_k127_6072161_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 409.0
HKD1_k127_6072161_10 - - - - 0.00000000000000000009918 89.0
HKD1_k127_6072161_11 - - - - 0.0000000000001519 71.0
HKD1_k127_6072161_12 Glycosyl transferase family 41 - - - 0.00000596 58.0
HKD1_k127_6072161_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 399.0
HKD1_k127_6072161_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 369.0
HKD1_k127_6072161_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009753 279.0
HKD1_k127_6072161_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
HKD1_k127_6072161_6 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000002465 178.0
HKD1_k127_6072161_7 methyltransferase - - - 0.00000000000000000000000000000000000000000001083 171.0
HKD1_k127_6072161_8 - - - - 0.000000000000000000000000000001446 128.0
HKD1_k127_6072161_9 Trypsin-like peptidase domain - - - 0.00000000000000000000006672 112.0
HKD1_k127_6072409_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 337.0
HKD1_k127_6072409_1 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009517 267.0
HKD1_k127_6072409_2 ATPase family associated with various cellular activities (AAA) K01990 - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
HKD1_k127_6072409_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000007432 77.0
HKD1_k127_6091595_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 418.0
HKD1_k127_6091595_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000003664 196.0
HKD1_k127_6091595_2 - - - - 0.00000000000000000000009838 107.0
HKD1_k127_6091595_3 Protein of unknown function (DUF1566) - - - 0.00000000000000000000485 100.0
HKD1_k127_6091595_5 methyltransferase - - - 0.0000000000000001787 80.0
HKD1_k127_6091595_6 - - - - 0.00000000006488 68.0
HKD1_k127_6091595_7 - - - - 0.0003573 49.0
HKD1_k127_6095702_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 528.0
HKD1_k127_6095702_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 482.0
HKD1_k127_6095702_2 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 388.0
HKD1_k127_6095702_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 328.0
HKD1_k127_6095702_4 nucleotidyltransferase activity K07075,K07076 - - 0.000000000000000000000000000000000000000000000000000004046 194.0
HKD1_k127_6095702_5 HEPN domain K07076 - - 0.0000000000000000000000000000000000000000000002102 171.0
HKD1_k127_6095702_6 YbbR-like protein - - - 0.00000000000000000000000000000000000001624 152.0
HKD1_k127_6095702_7 Methyltransferase domain - - - 0.000000000000000000000007222 113.0
HKD1_k127_6095702_8 Glycosyl transferase, family 2 - - - 0.0000000000003606 74.0
HKD1_k127_6115096_0 alpha amylase, catalytic K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 537.0
HKD1_k127_6115096_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 337.0
HKD1_k127_6115096_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000004242 236.0
HKD1_k127_6115096_3 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000003631 141.0
HKD1_k127_6121635_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 575.0
HKD1_k127_6121635_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 501.0
HKD1_k127_6121635_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
HKD1_k127_6121635_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
HKD1_k127_6121635_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001139 242.0
HKD1_k127_6121635_5 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000000000000000000009265 163.0
HKD1_k127_6121635_6 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000202 139.0
HKD1_k127_6124661_0 metal ion transmembrane transporter activity K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 533.0
HKD1_k127_6124661_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 419.0
HKD1_k127_6124661_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 355.0
HKD1_k127_6124661_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000009631 202.0
HKD1_k127_6124661_4 - - - - 0.00000000000000000000000000000000000000002185 154.0
HKD1_k127_6124661_5 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000001285 143.0
HKD1_k127_6142225_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1064.0
HKD1_k127_6142225_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 625.0
HKD1_k127_6142225_2 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 301.0
HKD1_k127_6142225_3 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 299.0
HKD1_k127_6142225_4 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 286.0
HKD1_k127_6142225_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000006829 233.0
HKD1_k127_6148640_0 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 423.0
HKD1_k127_6148640_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 428.0
HKD1_k127_6148640_2 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
HKD1_k127_6158633_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.122e-250 786.0
HKD1_k127_6158633_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 510.0
HKD1_k127_6158633_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 494.0
HKD1_k127_6158633_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 459.0
HKD1_k127_6158633_4 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000000000009231 205.0
HKD1_k127_6158633_5 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000004871 168.0
HKD1_k127_6158633_6 cellulase activity - - - 0.0000000000000000000000000000000000000001927 164.0
HKD1_k127_6158633_7 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.00000000000000000000000000000005125 129.0
HKD1_k127_6158633_8 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000003089 84.0
HKD1_k127_6158633_9 FecR protein - - - 0.00001832 55.0
HKD1_k127_6160920_0 Proton-conducting membrane transporter - - - 3.047e-263 826.0
HKD1_k127_6160920_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 1.431e-233 733.0
HKD1_k127_6160920_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000001532 227.0
HKD1_k127_6160920_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000309 220.0
HKD1_k127_6160920_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000006191 216.0
HKD1_k127_6160920_13 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000004685 179.0
HKD1_k127_6160920_14 - - - - 0.00000000000000000000000000000000000000001277 175.0
HKD1_k127_6160920_15 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000000004017 153.0
HKD1_k127_6160920_16 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000000001767 119.0
HKD1_k127_6160920_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 497.0
HKD1_k127_6160920_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 481.0
HKD1_k127_6160920_4 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 439.0
HKD1_k127_6160920_5 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 417.0
HKD1_k127_6160920_6 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 406.0
HKD1_k127_6160920_7 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001656 261.0
HKD1_k127_6160920_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000004136 237.0
HKD1_k127_6160920_9 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000001422 224.0
HKD1_k127_616463_0 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 424.0
HKD1_k127_616463_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
HKD1_k127_616463_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000001894 172.0
HKD1_k127_616463_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000227 164.0
HKD1_k127_616463_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000616 160.0
HKD1_k127_616463_5 Cytochrome c1 - - - 0.000000000000006868 78.0
HKD1_k127_6200460_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 445.0
HKD1_k127_6200460_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 285.0
HKD1_k127_6200460_2 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007625 245.0
HKD1_k127_6200460_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002656 241.0
HKD1_k127_6200460_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007571 237.0
HKD1_k127_6200460_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000005815 203.0
HKD1_k127_6200460_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000005129 215.0
HKD1_k127_6200460_7 Universal stress protein - - - 0.0000000000001814 76.0
HKD1_k127_6213127_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1070.0
HKD1_k127_6213127_1 Thioredoxin domain K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 528.0
HKD1_k127_6213127_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001127 243.0
HKD1_k127_6213127_11 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 253.0
HKD1_k127_6213127_12 Histidine kinase-like ATPases K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000002337 240.0
HKD1_k127_6213127_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000004647 221.0
HKD1_k127_6213127_14 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000002428 227.0
HKD1_k127_6213127_15 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000003025 222.0
HKD1_k127_6213127_16 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000002876 190.0
HKD1_k127_6213127_17 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000002534 151.0
HKD1_k127_6213127_18 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000004558 85.0
HKD1_k127_6213127_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
HKD1_k127_6213127_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 392.0
HKD1_k127_6213127_5 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 351.0
HKD1_k127_6213127_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001924 289.0
HKD1_k127_6213127_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006304 267.0
HKD1_k127_6213127_8 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001055 254.0
HKD1_k127_6213127_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005912 242.0
HKD1_k127_6216954_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.063e-263 822.0
HKD1_k127_6216954_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 542.0
HKD1_k127_6216954_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000005374 239.0
HKD1_k127_6216954_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000001581 153.0
HKD1_k127_6216954_4 ACT domain - - - 0.00002557 46.0
HKD1_k127_6237855_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 8.053e-238 747.0
HKD1_k127_6237855_1 PFAM Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 563.0
HKD1_k127_6237855_2 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000006618 239.0
HKD1_k127_6237855_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000001758 228.0
HKD1_k127_6237855_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000001422 186.0
HKD1_k127_6237855_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000436 160.0
HKD1_k127_6237855_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000004139 153.0
HKD1_k127_6237855_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000001077 133.0
HKD1_k127_6237855_8 TIGRFAM caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000004771 55.0
HKD1_k127_6284003_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 563.0
HKD1_k127_6329679_0 glycosyl transferase family 2 K21349 - 2.4.1.268 1.463e-197 623.0
HKD1_k127_6329679_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 507.0
HKD1_k127_6329679_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 344.0
HKD1_k127_6329679_3 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
HKD1_k127_6329679_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002452 247.0
HKD1_k127_6329679_5 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000000000000008944 220.0
HKD1_k127_6329679_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000001017 154.0
HKD1_k127_6329679_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000004936 101.0
HKD1_k127_6333478_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 321.0
HKD1_k127_6333478_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000004446 189.0
HKD1_k127_6375710_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 4.091e-205 673.0
HKD1_k127_6375710_1 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 327.0
HKD1_k127_6375710_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000005388 154.0
HKD1_k127_6375710_11 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.000000000000000000000000000000000001491 147.0
HKD1_k127_6375710_12 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000001771 64.0
HKD1_k127_6375710_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 303.0
HKD1_k127_6375710_3 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000116 299.0
HKD1_k127_6375710_4 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000006693 255.0
HKD1_k127_6375710_5 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000001493 220.0
HKD1_k127_6375710_6 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000003986 198.0
HKD1_k127_6375710_7 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000006955 193.0
HKD1_k127_6375710_8 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000007375 193.0
HKD1_k127_6375710_9 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000008089 186.0
HKD1_k127_6434223_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.275e-281 878.0
HKD1_k127_6434223_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000003585 59.0
HKD1_k127_646612_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 364.0
HKD1_k127_646612_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 335.0
HKD1_k127_646612_10 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000101 158.0
HKD1_k127_646612_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000002125 114.0
HKD1_k127_646612_12 STAS domain K04749 - - 0.00000000000000000000003903 102.0
HKD1_k127_646612_13 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000001225 100.0
HKD1_k127_646612_14 PFAM Mammalian cell entry related K02067 - - 0.00000000000000000001478 103.0
HKD1_k127_646612_15 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000000002899 87.0
HKD1_k127_646612_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 319.0
HKD1_k127_646612_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002102 273.0
HKD1_k127_646612_4 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
HKD1_k127_646612_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
HKD1_k127_646612_6 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001055 258.0
HKD1_k127_646612_7 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002551 225.0
HKD1_k127_646612_8 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HKD1_k127_646612_9 membrane K00389 - - 0.0000000000000000000000000000000000000000000000001544 179.0
HKD1_k127_6467072_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.124e-297 925.0
HKD1_k127_6467072_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 7.91e-257 812.0
HKD1_k127_6467072_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002836 227.0
HKD1_k127_6467072_11 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000004422 216.0
HKD1_k127_6467072_12 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000001327 206.0
HKD1_k127_6467072_13 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000002012 179.0
HKD1_k127_6467072_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000003074 180.0
HKD1_k127_6467072_15 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000007092 172.0
HKD1_k127_6467072_16 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000188 151.0
HKD1_k127_6467072_17 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000000000000000000000000001459 153.0
HKD1_k127_6467072_18 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000000000007613 128.0
HKD1_k127_6467072_19 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000003726 112.0
HKD1_k127_6467072_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 440.0
HKD1_k127_6467072_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 410.0
HKD1_k127_6467072_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 389.0
HKD1_k127_6467072_5 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 370.0
HKD1_k127_6467072_6 phosphoglycolate phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 345.0
HKD1_k127_6467072_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 329.0
HKD1_k127_6467072_8 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 299.0
HKD1_k127_6467072_9 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
HKD1_k127_6476504_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 561.0
HKD1_k127_6476504_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 308.0
HKD1_k127_6476504_3 Tetratricopeptide repeat - - - 0.000000000141 66.0
HKD1_k127_6491180_0 Transport of potassium into the cell K03549 - - 1.184e-248 781.0
HKD1_k127_6491180_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 476.0
HKD1_k127_6491180_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 373.0
HKD1_k127_6491180_3 Protein of unknown function (DUF2934) - - - 0.00006026 50.0
HKD1_k127_6541414_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1115.0
HKD1_k127_6541414_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 447.0
HKD1_k127_6581574_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.277e-304 953.0
HKD1_k127_6581574_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009067 275.0
HKD1_k127_6581574_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000003692 97.0
HKD1_k127_6581574_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000003104 71.0
HKD1_k127_6648722_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 503.0
HKD1_k127_6648722_1 PFAM transposase, mutator K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 444.0
HKD1_k127_6648722_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 347.0
HKD1_k127_6648722_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 325.0
HKD1_k127_6648722_4 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 293.0
HKD1_k127_6654459_0 General secretory system II, protein E domain protein K02652 - - 6.46e-216 685.0
HKD1_k127_6654459_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 544.0
HKD1_k127_6654459_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 498.0
HKD1_k127_6654459_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 366.0
HKD1_k127_6654459_4 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.000000000000000000000000009648 121.0
HKD1_k127_6654459_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000003872 105.0
HKD1_k127_6654459_6 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000415 70.0
HKD1_k127_6678352_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000001611 243.0
HKD1_k127_6678352_1 sulfatase - - - 0.000000000000000000000000000000000000000000000000008434 196.0
HKD1_k127_6683426_0 FecR protein - - - 1.568e-259 822.0
HKD1_k127_6683426_1 CHASE2 K01768 - 4.6.1.1 9.057e-229 730.0
HKD1_k127_6683426_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 9.557e-203 643.0
HKD1_k127_6683426_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 1.231e-195 618.0
HKD1_k127_6683426_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 451.0
HKD1_k127_6683426_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 288.0
HKD1_k127_6683426_6 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
HKD1_k127_6683426_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004661 225.0
HKD1_k127_6683426_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000005277 194.0
HKD1_k127_6683426_9 RNA-binding - - - 0.0000000000000000000000149 104.0
HKD1_k127_6684625_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.326e-208 654.0
HKD1_k127_6684625_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 576.0
HKD1_k127_6684625_10 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 348.0
HKD1_k127_6684625_11 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 336.0
HKD1_k127_6684625_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 321.0
HKD1_k127_6684625_13 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
HKD1_k127_6684625_14 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 259.0
HKD1_k127_6684625_15 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001158 253.0
HKD1_k127_6684625_16 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 242.0
HKD1_k127_6684625_17 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000008524 247.0
HKD1_k127_6684625_18 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000003906 249.0
HKD1_k127_6684625_19 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000009647 220.0
HKD1_k127_6684625_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 569.0
HKD1_k127_6684625_20 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000981 183.0
HKD1_k127_6684625_21 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000000000000000000000000000000000005912 185.0
HKD1_k127_6684625_22 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000007098 169.0
HKD1_k127_6684625_23 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000004207 133.0
HKD1_k127_6684625_24 protein-disulfide reductase activity - - - 0.00000000000000000000000000000472 124.0
HKD1_k127_6684625_25 Putative methyltransferase - - - 0.0000000000000000000000006295 120.0
HKD1_k127_6684625_26 EamA-like transporter family - - - 0.0000000000000000001534 94.0
HKD1_k127_6684625_28 Phosphopantetheine attachment site - - - 0.00000000304 61.0
HKD1_k127_6684625_29 cheY-homologous receiver domain - - - 0.000006546 59.0
HKD1_k127_6684625_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 502.0
HKD1_k127_6684625_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 479.0
HKD1_k127_6684625_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 473.0
HKD1_k127_6684625_6 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 468.0
HKD1_k127_6684625_7 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 388.0
HKD1_k127_6684625_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 380.0
HKD1_k127_6684625_9 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 366.0
HKD1_k127_6737873_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
HKD1_k127_6737873_1 Psort location Cytoplasmic, score 8.96 K09949 - - 0.000000000000000000000000000000003179 132.0
HKD1_k127_6737873_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000462 48.0
HKD1_k127_695470_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 516.0
HKD1_k127_695470_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 468.0
HKD1_k127_695470_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 310.0
HKD1_k127_695470_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
HKD1_k127_695470_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000001122 174.0
HKD1_k127_695470_5 ferric iron binding K02380 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564 - 0.000000000000000000000000000003263 129.0
HKD1_k127_695470_6 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000007473 112.0
HKD1_k127_695470_8 Prokaryotic cytochrome b561 K00127 - - 0.000002746 49.0
HKD1_k127_695470_9 ECF-type riboflavin transporter, S component - - - 0.0005491 44.0
HKD1_k127_6999745_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 293.0
HKD1_k127_6999745_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000008455 207.0
HKD1_k127_6999745_2 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000003495 205.0
HKD1_k127_6999745_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000002817 112.0
HKD1_k127_7057322_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 357.0
HKD1_k127_7057322_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
HKD1_k127_7057322_11 protein secretion K03116,K03117 - - 0.000000000002113 72.0
HKD1_k127_7057322_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 288.0
HKD1_k127_7057322_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 287.0
HKD1_k127_7057322_4 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000006335 231.0
HKD1_k127_7057322_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000005491 170.0
HKD1_k127_7057322_7 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000001501 136.0
HKD1_k127_7057322_8 bacterial (prokaryotic) histone like domain K04764 - - 0.00000000000000000000000002594 110.0
HKD1_k127_7057322_9 Addiction module toxin, RelE StbE family - - - 0.000000000000000000008115 94.0
HKD1_k127_7065587_0 ATPase BadF BadG BcrA BcrD type - - - 1.139e-314 983.0
HKD1_k127_7085011_0 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 374.0
HKD1_k127_7085011_1 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 298.0
HKD1_k127_7085011_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000007394 138.0
HKD1_k127_7086146_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1199.0
HKD1_k127_7086146_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 429.0
HKD1_k127_7086146_10 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
HKD1_k127_7086146_11 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000003926 223.0
HKD1_k127_7086146_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000001864 180.0
HKD1_k127_7086146_13 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000004155 163.0
HKD1_k127_7086146_14 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000595 150.0
HKD1_k127_7086146_15 energy transducer activity K03832 - - 0.00000000000000000000000000000000000001366 159.0
HKD1_k127_7086146_16 Universal stress protein family - - - 0.00000000000000000000000000000000000002827 148.0
HKD1_k127_7086146_17 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000008888 149.0
HKD1_k127_7086146_18 proteolysis K03665 - - 0.00000000000000000000000000003952 122.0
HKD1_k127_7086146_19 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000006037 106.0
HKD1_k127_7086146_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 415.0
HKD1_k127_7086146_20 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000007243 93.0
HKD1_k127_7086146_22 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000004952 88.0
HKD1_k127_7086146_23 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000003333 74.0
HKD1_k127_7086146_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00004319 48.0
HKD1_k127_7086146_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 424.0
HKD1_k127_7086146_4 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 388.0
HKD1_k127_7086146_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 364.0
HKD1_k127_7086146_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 344.0
HKD1_k127_7086146_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 344.0
HKD1_k127_7086146_8 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 308.0
HKD1_k127_7086146_9 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000004478 268.0
HKD1_k127_7086726_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1154.0
HKD1_k127_7086726_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.293e-253 803.0
HKD1_k127_7086726_10 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000007628 247.0
HKD1_k127_7086726_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000003655 197.0
HKD1_k127_7086726_12 transcription factor binding - - - 0.00000000000000000000000004994 111.0
HKD1_k127_7086726_13 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000001182 110.0
HKD1_k127_7086726_14 Membrane - - - 0.0000000000000000000000001325 112.0
HKD1_k127_7086726_15 Multicopper K06324 - 1.16.3.3 0.00000000000000000000001336 110.0
HKD1_k127_7086726_16 YtxH-like protein - - - 0.00000000000000000004264 93.0
HKD1_k127_7086726_17 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000009938 63.0
HKD1_k127_7086726_18 Bacterial Ig-like domain (group 3) K20276 - - 0.000001492 61.0
HKD1_k127_7086726_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 569.0
HKD1_k127_7086726_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 519.0
HKD1_k127_7086726_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 514.0
HKD1_k127_7086726_5 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 527.0
HKD1_k127_7086726_6 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 437.0
HKD1_k127_7086726_7 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001832 284.0
HKD1_k127_7086726_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 262.0
HKD1_k127_7086726_9 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 262.0
HKD1_k127_7097583_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 400.0
HKD1_k127_7097583_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005339 283.0
HKD1_k127_7097583_2 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000319 166.0
HKD1_k127_7097583_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000001318 154.0
HKD1_k127_7099889_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.4e-293 920.0
HKD1_k127_7099889_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 598.0
HKD1_k127_7099889_10 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000007885 113.0
HKD1_k127_7099889_11 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000005006 91.0
HKD1_k127_7099889_12 Fimbrial assembly protein (PilN) K02663 - - 0.00000002233 64.0
HKD1_k127_7099889_13 Protein of unknown function (DUF721) - - - 0.000006894 55.0
HKD1_k127_7099889_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 547.0
HKD1_k127_7099889_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 344.0
HKD1_k127_7099889_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 329.0
HKD1_k127_7099889_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 331.0
HKD1_k127_7099889_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
HKD1_k127_7099889_7 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 283.0
HKD1_k127_7099889_8 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HKD1_k127_7099889_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000003945 147.0
HKD1_k127_7105681_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 3.211e-257 812.0
HKD1_k127_7105681_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 492.0
HKD1_k127_7105681_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001564 248.0
HKD1_k127_71064_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.446e-211 661.0
HKD1_k127_71064_1 Aldehyde dehydrogenase family K22187 - - 6.135e-204 645.0
HKD1_k127_71064_10 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 421.0
HKD1_k127_71064_11 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 425.0
HKD1_k127_71064_12 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
HKD1_k127_71064_13 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 414.0
HKD1_k127_71064_14 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 393.0
HKD1_k127_71064_15 PFAM MscS Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 382.0
HKD1_k127_71064_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 350.0
HKD1_k127_71064_17 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
HKD1_k127_71064_18 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 322.0
HKD1_k127_71064_19 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 323.0
HKD1_k127_71064_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 578.0
HKD1_k127_71064_20 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 323.0
HKD1_k127_71064_21 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
HKD1_k127_71064_22 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 300.0
HKD1_k127_71064_23 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004099 241.0
HKD1_k127_71064_24 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000002087 230.0
HKD1_k127_71064_25 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000002944 211.0
HKD1_k127_71064_26 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD1_k127_71064_27 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000004459 209.0
HKD1_k127_71064_28 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000009454 155.0
HKD1_k127_71064_29 Membrane - - - 0.000000000000000000000000000000000001369 142.0
HKD1_k127_71064_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 552.0
HKD1_k127_71064_30 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001554 137.0
HKD1_k127_71064_31 Pyrophosphatase - - - 0.0000000000000000000000000000000001722 135.0
HKD1_k127_71064_32 - - - - 0.0000000000000000000000222 107.0
HKD1_k127_71064_33 YtxH-like protein - - - 0.00000000000000007389 84.0
HKD1_k127_71064_35 - - - - 0.000000000000318 73.0
HKD1_k127_71064_36 Chemotaxis phosphatase CheX - - - 0.000000005688 62.0
HKD1_k127_71064_37 - - - - 0.000009213 52.0
HKD1_k127_71064_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 519.0
HKD1_k127_71064_5 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 503.0
HKD1_k127_71064_6 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 488.0
HKD1_k127_71064_7 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 487.0
HKD1_k127_71064_8 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 473.0
HKD1_k127_71064_9 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 459.0
HKD1_k127_7109973_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002017 276.0
HKD1_k127_7109973_1 lyase activity - - - 0.000000000000000000003926 110.0
HKD1_k127_7109973_2 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000009252 99.0
HKD1_k127_7121396_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000001349 97.0
HKD1_k127_7121396_1 Thioredoxin-like domain K03671 - - 0.000000002441 58.0
HKD1_k127_712603_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1240.0
HKD1_k127_712603_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1191.0
HKD1_k127_712603_10 HNH nucleases - - - 0.000000000000000000000000000000000000000000003594 166.0
HKD1_k127_712603_11 GAF domain K02584 - - 0.00000000000000000000000000000000000000000002068 166.0
HKD1_k127_712603_12 translation release factor activity - - - 0.000000000000000000000000000000000000003498 150.0
HKD1_k127_712603_13 response regulator, receiver K03413 - - 0.00000000000000000000000004584 111.0
HKD1_k127_712603_14 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000003175 98.0
HKD1_k127_712603_15 Protein of unknown function (DUF1189) - - - 0.000000000000000003485 94.0
HKD1_k127_712603_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000009234 88.0
HKD1_k127_712603_17 electron transfer activity K05337,K17247 - - 0.000000000003851 67.0
HKD1_k127_712603_2 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 475.0
HKD1_k127_712603_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 455.0
HKD1_k127_712603_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 445.0
HKD1_k127_712603_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 430.0
HKD1_k127_712603_6 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 374.0
HKD1_k127_712603_7 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 333.0
HKD1_k127_712603_8 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000002269 221.0
HKD1_k127_712603_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000003945 219.0
HKD1_k127_7145893_0 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 617.0
HKD1_k127_7157234_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 548.0
HKD1_k127_7157234_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 328.0
HKD1_k127_7157234_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000008624 245.0
HKD1_k127_7157234_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001751 228.0
HKD1_k127_7157234_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001822 131.0
HKD1_k127_7157234_5 - - - - 0.00000000000000000000001088 104.0
HKD1_k127_7157234_6 Protein of unknown function (DUF3187) - - - 0.00000000000000000003474 103.0
HKD1_k127_7157234_7 - - - - 0.000000000005988 67.0
HKD1_k127_7157234_8 DnaJ and TPR domain protein K09523 - - 0.000000001629 67.0
HKD1_k127_7180038_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000175 231.0
HKD1_k127_7180038_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000001932 212.0
HKD1_k127_7180038_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000009082 227.0
HKD1_k127_7207606_0 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 3.75e-304 960.0
HKD1_k127_7218545_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 7.074e-305 948.0
HKD1_k127_7218545_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 304.0
HKD1_k127_7218545_2 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000002555 163.0
HKD1_k127_7220676_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 419.0
HKD1_k127_7220676_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 373.0
HKD1_k127_7231891_0 COG0058 Glucan phosphorylase - - - 4.424e-265 826.0
HKD1_k127_7231891_1 Histidine kinase - - - 3.955e-201 662.0
HKD1_k127_7231891_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
HKD1_k127_7231891_11 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000001658 194.0
HKD1_k127_7231891_12 MgtC family K07507 - - 0.000000000000000000000000000000000000001848 156.0
HKD1_k127_7231891_13 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000005935 152.0
HKD1_k127_7231891_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000001061 140.0
HKD1_k127_7231891_15 - - - - 0.0000000000000000000000000007778 113.0
HKD1_k127_7231891_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 580.0
HKD1_k127_7231891_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 553.0
HKD1_k127_7231891_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 471.0
HKD1_k127_7231891_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 465.0
HKD1_k127_7231891_6 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
HKD1_k127_7231891_7 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 313.0
HKD1_k127_7231891_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 308.0
HKD1_k127_7231891_9 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002463 256.0
HKD1_k127_7242892_0 Multicopper oxidase - - - 5.465e-239 758.0
HKD1_k127_7242892_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 468.0
HKD1_k127_7242892_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 356.0
HKD1_k127_7242892_3 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001021 282.0
HKD1_k127_7242892_4 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000001367 248.0
HKD1_k127_7242892_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000969 163.0
HKD1_k127_7242892_6 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000004121 166.0
HKD1_k127_7242892_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000001392 154.0
HKD1_k127_7242892_8 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000006939 149.0
HKD1_k127_7242892_9 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000102 108.0
HKD1_k127_7260016_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.253e-274 871.0
HKD1_k127_7260016_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 2.811e-257 804.0
HKD1_k127_7260016_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 299.0
HKD1_k127_7260016_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 290.0
HKD1_k127_7260016_12 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008905 299.0
HKD1_k127_7260016_13 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009062 256.0
HKD1_k127_7260016_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 243.0
HKD1_k127_7260016_15 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001989 234.0
HKD1_k127_7260016_16 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000001634 220.0
HKD1_k127_7260016_17 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000000000000073 203.0
HKD1_k127_7260016_18 - - - - 0.0000000000000000000000000000000000000000000000000000000232 207.0
HKD1_k127_7260016_19 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000004205 185.0
HKD1_k127_7260016_2 DNA polymerase K02347 - - 1.334e-228 721.0
HKD1_k127_7260016_20 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000003892 170.0
HKD1_k127_7260016_21 aminopeptidase N - - - 0.000000000000000000000000000000000000000000298 169.0
HKD1_k127_7260016_22 response regulator K02485 - - 0.00000000000000000000002607 104.0
HKD1_k127_7260016_23 - - - - 0.00000000000000000001118 96.0
HKD1_k127_7260016_24 - - - - 0.0000002088 55.0
HKD1_k127_7260016_25 helix_turn_helix ASNC type K03718 - - 0.00001663 51.0
HKD1_k127_7260016_26 Protein of unknown function (DUF2892) - - - 0.0005693 43.0
HKD1_k127_7260016_3 Fructose-bisphosphate aldolase class-II - - - 7.058e-197 625.0
HKD1_k127_7260016_4 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 574.0
HKD1_k127_7260016_5 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 532.0
HKD1_k127_7260016_6 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 401.0
HKD1_k127_7260016_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 369.0
HKD1_k127_7260016_8 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 338.0
HKD1_k127_7260016_9 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
HKD1_k127_7281752_0 Aminotransferase class-III K00823 - 2.6.1.19 1.573e-195 619.0
HKD1_k127_7281752_1 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 489.0
HKD1_k127_7281752_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 340.0
HKD1_k127_7281752_11 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
HKD1_k127_7281752_12 response regulator K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008015 252.0
HKD1_k127_7281752_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001322 267.0
HKD1_k127_7281752_14 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000289 209.0
HKD1_k127_7281752_15 Putative Phosphatase - - - 0.00000000000000000000000000000000000000000000102 173.0
HKD1_k127_7281752_16 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000005001 148.0
HKD1_k127_7281752_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000000001216 64.0
HKD1_k127_7281752_2 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 451.0
HKD1_k127_7281752_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 398.0
HKD1_k127_7281752_4 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 388.0
HKD1_k127_7281752_5 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 366.0
HKD1_k127_7281752_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 362.0
HKD1_k127_7281752_7 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 369.0
HKD1_k127_7281752_8 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 340.0
HKD1_k127_7281752_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD1_k127_7356188_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.932e-199 638.0
HKD1_k127_7356188_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 552.0
HKD1_k127_7356188_10 LPP20 lipoprotein K09860 - - 0.00000000009084 73.0
HKD1_k127_7356188_11 LPP20 lipoprotein - - - 0.00000004872 62.0
HKD1_k127_7356188_12 Curli production assembly/transport component CsgG - - - 0.00002224 55.0
HKD1_k127_7356188_2 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006681 280.0
HKD1_k127_7356188_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001939 284.0
HKD1_k127_7356188_4 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000001322 207.0
HKD1_k127_7356188_5 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000000002627 180.0
HKD1_k127_7356188_6 - - - - 0.000000000000000000000004796 110.0
HKD1_k127_7356188_7 - - - - 0.000000000000000000000337 101.0
HKD1_k127_7356188_8 - - - - 0.00000000000002561 84.0
HKD1_k127_7356188_9 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000001109 73.0
HKD1_k127_7373712_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 586.0
HKD1_k127_7373712_1 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
HKD1_k127_7373712_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000282 216.0
HKD1_k127_7373712_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000001019 207.0
HKD1_k127_7373712_4 Transcriptional regulatory protein, C terminal - - - 0.000000002116 66.0
HKD1_k127_7373712_5 Protein of unknown function (DUF2845) - - - 0.0000001336 58.0
HKD1_k127_7379956_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0 1170.0
HKD1_k127_7379956_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.242e-302 935.0
HKD1_k127_7379956_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000002153 195.0
HKD1_k127_7379956_11 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000009066 190.0
HKD1_k127_7379956_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000267 148.0
HKD1_k127_7379956_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000008783 130.0
HKD1_k127_7379956_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.221e-245 771.0
HKD1_k127_7379956_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 3.12e-220 689.0
HKD1_k127_7379956_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.176e-196 627.0
HKD1_k127_7379956_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 496.0
HKD1_k127_7379956_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 501.0
HKD1_k127_7379956_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 313.0
HKD1_k127_7379956_8 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000001229 211.0
HKD1_k127_7379956_9 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000287 206.0
HKD1_k127_7393888_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 607.0
HKD1_k127_7393888_1 PFAM PfkB K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 388.0
HKD1_k127_7393888_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005715 280.0
HKD1_k127_7393888_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000001669 246.0
HKD1_k127_7393888_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
HKD1_k127_7393888_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000006703 113.0
HKD1_k127_7393888_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000006385 96.0
HKD1_k127_7393888_7 protein histidine kinase activity K02491,K13533,K14986 - 2.7.13.3 0.000021 55.0
HKD1_k127_7408664_0 Glycosyl hydrolases family 15 - - - 4.081e-250 788.0
HKD1_k127_7408664_1 Protein of unknown function, DUF255 K06888 - - 1.825e-234 744.0
HKD1_k127_7408664_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 334.0
HKD1_k127_7408664_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
HKD1_k127_7408664_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002337 264.0
HKD1_k127_7408664_13 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HKD1_k127_7408664_14 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000009788 239.0
HKD1_k127_7408664_15 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
HKD1_k127_7408664_16 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
HKD1_k127_7408664_17 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000002809 180.0
HKD1_k127_7408664_18 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000003544 169.0
HKD1_k127_7408664_19 Cytochrome P460 - - - 0.0000000000000000000000000000000000000004045 154.0
HKD1_k127_7408664_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 4.473e-221 696.0
HKD1_k127_7408664_20 copper resistance K07245,K14166 - - 0.0000000000000000000000000000000000004338 154.0
HKD1_k127_7408664_21 response to copper ion K07156,K14166 - - 0.0000000000000000000000000000000004388 135.0
HKD1_k127_7408664_22 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000000006367 114.0
HKD1_k127_7408664_23 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000004654 99.0
HKD1_k127_7408664_24 - - - - 0.0000000000000000000006194 97.0
HKD1_k127_7408664_25 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.00000000000000000001447 102.0
HKD1_k127_7408664_26 response to copper ion - - - 0.0000000000000009347 88.0
HKD1_k127_7408664_27 - - - - 0.00000000000002807 78.0
HKD1_k127_7408664_28 snoRNA binding - - - 0.0000009226 53.0
HKD1_k127_7408664_29 transferase activity, transferring glycosyl groups - - - 0.000001036 57.0
HKD1_k127_7408664_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 487.0
HKD1_k127_7408664_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 468.0
HKD1_k127_7408664_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 430.0
HKD1_k127_7408664_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 362.0
HKD1_k127_7408664_7 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 368.0
HKD1_k127_7408664_8 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 388.0
HKD1_k127_7408664_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 366.0
HKD1_k127_7418848_0 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
HKD1_k127_7418848_1 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000009813 180.0
HKD1_k127_7418848_2 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000000000002402 180.0
HKD1_k127_7481906_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 409.0
HKD1_k127_7481906_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 355.0
HKD1_k127_7481906_2 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 310.0
HKD1_k127_7481906_3 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000009308 194.0
HKD1_k127_7481906_4 Protein of unknown function (DUF2905) - - - 0.0000000000000000000001466 98.0
HKD1_k127_7498291_0 Glycogen debranching enzyme - - - 0.0 1581.0
HKD1_k127_7498291_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 336.0
HKD1_k127_7498291_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 309.0
HKD1_k127_7498291_3 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 250.0
HKD1_k127_7498291_4 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000003166 153.0
HKD1_k127_7498291_5 ABC transporter substrate-binding protein K02051,K15551 - - 0.0000000000000000000000001142 120.0
HKD1_k127_7498291_6 - - - - 0.0000002176 59.0
HKD1_k127_7510997_0 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 571.0
HKD1_k127_7510997_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 328.0
HKD1_k127_7510997_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 323.0
HKD1_k127_7510997_3 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000001956 116.0
HKD1_k127_7510997_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000001686 51.0
HKD1_k127_7554342_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 2.767e-315 981.0
HKD1_k127_7554342_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 414.0
HKD1_k127_7554342_10 Short C-terminal domain K08982 - - 0.0000000000000001089 81.0
HKD1_k127_7554342_11 YtkA-like - - - 0.000000000007295 71.0
HKD1_k127_7554342_12 Protein of unknown function with PCYCGC motif - - - 0.00000009437 57.0
HKD1_k127_7554342_13 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000001979 56.0
HKD1_k127_7554342_14 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000003394 49.0
HKD1_k127_7554342_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 408.0
HKD1_k127_7554342_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 318.0
HKD1_k127_7554342_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 295.0
HKD1_k127_7554342_5 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007887 267.0
HKD1_k127_7554342_6 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007522 234.0
HKD1_k127_7554342_7 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000000003653 188.0
HKD1_k127_7554342_8 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000819 133.0
HKD1_k127_7554342_9 - - - - 0.000000000000000001232 89.0
HKD1_k127_7599209_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.691e-270 844.0
HKD1_k127_7599209_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 397.0
HKD1_k127_7599209_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000001355 113.0
HKD1_k127_7599209_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 352.0
HKD1_k127_7599209_3 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000001155 196.0
HKD1_k127_7599209_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001102 189.0
HKD1_k127_7599209_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000000003298 184.0
HKD1_k127_7599209_6 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000008231 166.0
HKD1_k127_7599209_7 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000001902 161.0
HKD1_k127_7599209_8 Sigma-54 dependent response regulator K07714 - - 0.000000000000000000000000000001136 124.0
HKD1_k127_7599209_9 DRTGG domain - - - 0.000000000000000000000000001094 115.0
HKD1_k127_7622174_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.039e-319 994.0
HKD1_k127_7622174_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 435.0
HKD1_k127_7622174_2 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 410.0
HKD1_k127_7622174_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
HKD1_k127_7622174_4 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000005931 228.0
HKD1_k127_7622174_5 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000003806 176.0
HKD1_k127_7622174_6 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000005563 147.0
HKD1_k127_7674627_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 608.0
HKD1_k127_7674627_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 440.0
HKD1_k127_7674627_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 310.0
HKD1_k127_7674627_3 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002526 259.0
HKD1_k127_7674627_4 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000203 106.0
HKD1_k127_7674627_5 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000001494 75.0
HKD1_k127_7674627_6 - - - - 0.000000000002034 72.0
HKD1_k127_77187_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 359.0
HKD1_k127_77187_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
HKD1_k127_7773229_0 cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 314.0
HKD1_k127_7773229_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000008144 167.0
HKD1_k127_7773229_2 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000006773 123.0
HKD1_k127_7773229_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000424 130.0
HKD1_k127_7773618_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.558e-286 893.0
HKD1_k127_7773618_1 Sigma-54 interaction domain - - - 1.618e-217 685.0
HKD1_k127_7773618_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 467.0
HKD1_k127_7773618_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 327.0
HKD1_k127_7773618_6 - - - - 0.0000000000000001794 83.0
HKD1_k127_7773618_7 - - - - 0.00007138 47.0
HKD1_k127_7783971_0 PD-(D/E)XK nuclease superfamily - - - 6.62e-230 747.0
HKD1_k127_7783971_1 Belongs to the helicase family. UvrD subfamily - - - 3.548e-215 702.0
HKD1_k127_7783971_2 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 414.0
HKD1_k127_7783971_3 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 355.0
HKD1_k127_7783971_4 GYD domain - - - 0.000000000000000000000000000000003705 131.0
HKD1_k127_7789554_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 594.0
HKD1_k127_7789554_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 359.0
HKD1_k127_7789554_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000009171 145.0
HKD1_k127_7789554_4 metalloendopeptidase activity - - - 0.0000000000000000001524 100.0
HKD1_k127_7789554_5 lyase activity - - - 0.0000000000004999 78.0
HKD1_k127_789109_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.149e-239 749.0
HKD1_k127_789109_1 Endoribonuclease that initiates mRNA decay K18682 - - 3.243e-205 651.0
HKD1_k127_789109_10 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000006324 180.0
HKD1_k127_789109_11 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000095 168.0
HKD1_k127_789109_12 KR domain - - - 0.000000000000000000000000000000000000002049 152.0
HKD1_k127_789109_13 CHRD domain - - - 0.0000000000000000000000000000000000002728 145.0
HKD1_k127_789109_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000002125 145.0
HKD1_k127_789109_15 Flavodoxin-like fold - - - 0.00000000000000000000000000000000004019 144.0
HKD1_k127_789109_16 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000004259 136.0
HKD1_k127_789109_17 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000001801 123.0
HKD1_k127_789109_18 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000171 103.0
HKD1_k127_789109_19 KR domain - - - 0.000000000000000000001682 96.0
HKD1_k127_789109_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 471.0
HKD1_k127_789109_20 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000575 90.0
HKD1_k127_789109_21 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000001548 82.0
HKD1_k127_789109_22 - - - - 0.000000000001247 70.0
HKD1_k127_789109_23 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000008223 66.0
HKD1_k127_789109_24 - - - - 0.00005458 49.0
HKD1_k127_789109_3 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 361.0
HKD1_k127_789109_4 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 282.0
HKD1_k127_789109_5 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000000000000000000000002669 223.0
HKD1_k127_789109_6 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000003072 214.0
HKD1_k127_789109_7 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
HKD1_k127_789109_8 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000002958 194.0
HKD1_k127_789109_9 WHG domain - - - 0.000000000000000000000000000000000000000000000000006989 188.0
HKD1_k127_794732_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1444.0
HKD1_k127_794732_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 9.935e-195 617.0
HKD1_k127_794732_10 Universal stress protein family - - - 0.0000000002756 68.0
HKD1_k127_794732_11 Universal stress protein family - - - 0.000000000364 70.0
HKD1_k127_794732_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000001245 60.0
HKD1_k127_794732_13 Belongs to the universal stress protein A family - - - 0.0000003791 59.0
HKD1_k127_794732_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 430.0
HKD1_k127_794732_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 419.0
HKD1_k127_794732_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 408.0
HKD1_k127_794732_5 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 395.0
HKD1_k127_794732_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
HKD1_k127_794732_7 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000652 189.0
HKD1_k127_794732_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000002378 166.0
HKD1_k127_794732_9 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000005683 152.0