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Overview

ID MAG01723
Name HKD1_bin.40
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class HRBIN11
Order JAKEFK01
Family JAKEFK01
Genus
Species
Assembly information
Completeness (%) 65.11
Contamination (%) 0.17
GC content (%) 59.0
N50 (bp) 5,826
Genome size (bp) 3,962,094

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3402

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1010587_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 502.0
HKD1_k127_1010587_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 343.0
HKD1_k127_1010587_2 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 311.0
HKD1_k127_101676_0 lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000001433 205.0
HKD1_k127_101676_1 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000367 138.0
HKD1_k127_101676_2 Major Facilitator - - - 0.000000000000000003813 97.0
HKD1_k127_1018014_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 485.0
HKD1_k127_1018014_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 422.0
HKD1_k127_1018014_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 352.0
HKD1_k127_1018014_3 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000001378 159.0
HKD1_k127_1018014_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000005001 111.0
HKD1_k127_1018014_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000008397 64.0
HKD1_k127_1031126_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 469.0
HKD1_k127_1031126_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006983 254.0
HKD1_k127_1031126_2 - - - - 0.000000000000000000000002874 107.0
HKD1_k127_1039513_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 461.0
HKD1_k127_1039513_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000002956 179.0
HKD1_k127_1039513_2 protein contain chitin-binding domain type 3 - - - 0.0000000000000000000000000000000001459 147.0
HKD1_k127_104410_0 Response regulator receiver - - - 5.664e-196 620.0
HKD1_k127_104410_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 493.0
HKD1_k127_104410_2 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 458.0
HKD1_k127_104410_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000005395 167.0
HKD1_k127_1047805_0 - - - - 0.00000000000000000000000000000000000000000000000000002962 194.0
HKD1_k127_1047805_1 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000001432 149.0
HKD1_k127_1047805_2 Vitamin k epoxide reductase - - - 0.00000000000000009998 93.0
HKD1_k127_1058270_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 387.0
HKD1_k127_1058270_1 Thioesterase K07107 - - 0.00000000000000000000000008614 115.0
HKD1_k127_1058270_2 E-Z type HEAT repeats - - - 0.0000000052 65.0
HKD1_k127_1064932_0 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 587.0
HKD1_k127_1064932_1 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 488.0
HKD1_k127_1064932_2 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
HKD1_k127_1083813_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 435.0
HKD1_k127_1083813_1 - - - - 0.0000000000000000000000000000000000000000000000000002236 193.0
HKD1_k127_1083813_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000003842 71.0
HKD1_k127_109053_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1093.0
HKD1_k127_109053_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 472.0
HKD1_k127_109053_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
HKD1_k127_109053_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 397.0
HKD1_k127_109053_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000007625 147.0
HKD1_k127_109053_5 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000001937 55.0
HKD1_k127_1091062_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 464.0
HKD1_k127_1091062_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 340.0
HKD1_k127_1091062_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002126 279.0
HKD1_k127_1091062_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000001919 148.0
HKD1_k127_110116_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 443.0
HKD1_k127_110116_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
HKD1_k127_110116_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000003133 177.0
HKD1_k127_1106805_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 320.0
HKD1_k127_1106805_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 324.0
HKD1_k127_1106805_2 regulation of mitotic cell cycle - - - 0.000002119 61.0
HKD1_k127_1131512_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 496.0
HKD1_k127_1131512_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
HKD1_k127_1131512_2 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 394.0
HKD1_k127_1131512_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 374.0
HKD1_k127_1131512_4 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000005736 163.0
HKD1_k127_1139637_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 513.0
HKD1_k127_1139637_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 360.0
HKD1_k127_1139637_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 329.0
HKD1_k127_1139637_3 histone H2A K63-linked ubiquitination K02283 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000001591 74.0
HKD1_k127_1151819_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 339.0
HKD1_k127_1151819_1 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000000007461 203.0
HKD1_k127_1151819_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000005182 196.0
HKD1_k127_1151819_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000306 96.0
HKD1_k127_115490_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 509.0
HKD1_k127_115490_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 438.0
HKD1_k127_115490_2 Domain of unknown function (DUF4037) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001468 272.0
HKD1_k127_1169034_0 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 418.0
HKD1_k127_1169034_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 338.0
HKD1_k127_1169034_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
HKD1_k127_1169034_3 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000006184 129.0
HKD1_k127_1169034_4 PspA/IM30 family K03969 - - 0.00000006206 63.0
HKD1_k127_1174772_0 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000001534 212.0
HKD1_k127_1174772_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000001217 172.0
HKD1_k127_1174772_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000001264 161.0
HKD1_k127_1174772_3 Hydrolase, NUDIX family K03574 - 3.6.1.55 0.0000000000000000000000000000000000147 139.0
HKD1_k127_1190651_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 404.0
HKD1_k127_1190651_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
HKD1_k127_1190651_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005186 245.0
HKD1_k127_1190651_3 Transposase IS200 like - - - 0.00000000000000000000000000000005338 135.0
HKD1_k127_1190651_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0001904 52.0
HKD1_k127_1205709_0 Large extracellular alpha-helical protein K06894 - - 8.636e-319 1019.0
HKD1_k127_1205709_1 cellulase activity - - - 5.281e-271 873.0
HKD1_k127_1205709_2 protease K09607 - - 0.000000009112 70.0
HKD1_k127_1205709_3 Endonuclease I - - - 0.00000002741 68.0
HKD1_k127_1214854_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.992e-221 698.0
HKD1_k127_1214854_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000001726 199.0
HKD1_k127_1214854_2 Protein tyrosine kinase - - - 0.000000000001189 70.0
HKD1_k127_1221905_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 393.0
HKD1_k127_1221905_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 368.0
HKD1_k127_1221905_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
HKD1_k127_1221905_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
HKD1_k127_1221905_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 286.0
HKD1_k127_1221905_5 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001821 259.0
HKD1_k127_1221905_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406,K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
HKD1_k127_1221905_7 Hydrogenase maturation protease - - - 0.000000000000000000000009912 107.0
HKD1_k127_1225018_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000001131 215.0
HKD1_k127_1225018_1 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000002707 210.0
HKD1_k127_1236308_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000001649 235.0
HKD1_k127_1236308_1 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000004115 164.0
HKD1_k127_1236308_2 - - - - 0.000000000000000000000000000000000000000001591 161.0
HKD1_k127_1236308_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000001715 123.0
HKD1_k127_1237383_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 378.0
HKD1_k127_1237383_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000004152 242.0
HKD1_k127_1237383_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000007297 166.0
HKD1_k127_1237383_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000001073 158.0
HKD1_k127_1243121_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 317.0
HKD1_k127_1243121_1 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000016 288.0
HKD1_k127_1254949_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 483.0
HKD1_k127_1254949_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 405.0
HKD1_k127_1254949_2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000003458 229.0
HKD1_k127_1254949_3 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
HKD1_k127_1254949_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000001253 118.0
HKD1_k127_1254949_5 Cell division protein FtsQ K03589 - - 0.0000000000000373 82.0
HKD1_k127_1265797_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 448.0
HKD1_k127_1265797_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 374.0
HKD1_k127_1269170_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 413.0
HKD1_k127_1269170_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
HKD1_k127_1269170_2 transcriptional regulator - - - 0.000000000000000000000000000000000000001954 159.0
HKD1_k127_1269170_3 Methylase involved in ubiquinone menaquinone biosynthesis K00598 - 2.1.1.144 0.00007561 54.0
HKD1_k127_1286383_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 530.0
HKD1_k127_1286383_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000002159 186.0
HKD1_k127_1286383_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000188 170.0
HKD1_k127_1286383_3 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000714 163.0
HKD1_k127_1286383_4 Biotin-lipoyl like K02005 - - 0.00000000000002378 83.0
HKD1_k127_1286383_5 - - - - 0.00000000006083 73.0
HKD1_k127_1290113_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001496 273.0
HKD1_k127_1290113_1 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000001162 115.0
HKD1_k127_1290113_2 membrane - - - 0.00000000000000000000002426 99.0
HKD1_k127_1290113_3 Fungalysin metallopeptidase (M36) K01417 - - 0.0000000000004625 83.0
HKD1_k127_1319307_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 379.0
HKD1_k127_1319307_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000002266 197.0
HKD1_k127_1319307_2 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000000004024 211.0
HKD1_k127_1319307_3 radical SAM domain protein - - - 0.00000000000000000000000000008686 131.0
HKD1_k127_1319307_4 positive regulation of growth K19687 - - 0.000116 54.0
HKD1_k127_1321788_0 Alpha-amylase domain K01176 - 3.2.1.1 1.554e-221 696.0
HKD1_k127_1321788_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 570.0
HKD1_k127_1321788_2 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 515.0
HKD1_k127_1321788_3 Bacterial extracellular solute-binding protein K15770 - - 0.0000000000000000000000000000000000000002599 152.0
HKD1_k127_1321788_4 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000006167 70.0
HKD1_k127_1334713_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000003297 248.0
HKD1_k127_1334713_1 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000002104 120.0
HKD1_k127_1334713_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000316 117.0
HKD1_k127_1342819_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 397.0
HKD1_k127_1342819_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 299.0
HKD1_k127_1342819_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
HKD1_k127_1342819_3 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000008126 118.0
HKD1_k127_1342819_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000001147 114.0
HKD1_k127_1359776_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 482.0
HKD1_k127_1359776_1 aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 357.0
HKD1_k127_1359776_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000002455 220.0
HKD1_k127_1359776_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000009719 126.0
HKD1_k127_1359776_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000696 82.0
HKD1_k127_1369754_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 365.0
HKD1_k127_1369754_1 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
HKD1_k127_1369754_2 PFAM Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005311 231.0
HKD1_k127_1377341_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 427.0
HKD1_k127_1377341_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 372.0
HKD1_k127_1377341_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
HKD1_k127_1377341_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
HKD1_k127_1377341_4 - - - - 0.0000000000000004967 86.0
HKD1_k127_1378215_0 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 335.0
HKD1_k127_1378215_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000002294 233.0
HKD1_k127_1378215_2 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000001293 211.0
HKD1_k127_1378215_3 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000009371 191.0
HKD1_k127_1412177_0 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 2.075e-208 662.0
HKD1_k127_1412177_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000008657 143.0
HKD1_k127_1412177_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000009024 145.0
HKD1_k127_1412177_3 DinB superfamily - - - 0.000000000000000000000000000001015 128.0
HKD1_k127_1412177_4 Cytochrome c K02275,K17223 - 1.9.3.1 0.000000000000000003392 94.0
HKD1_k127_1424243_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
HKD1_k127_1424243_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000448 164.0
HKD1_k127_1424798_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 331.0
HKD1_k127_1424798_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004033 254.0
HKD1_k127_1424798_2 repeat-containing protein - - - 0.00000009628 60.0
HKD1_k127_1443009_0 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 598.0
HKD1_k127_1443009_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000001026 255.0
HKD1_k127_1443009_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K05970 - 3.1.1.53 0.000000007372 70.0
HKD1_k127_1452132_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 443.0
HKD1_k127_1452132_1 Carbon starvation protein K06200 - - 0.0000000000000000000000000000001968 128.0
HKD1_k127_1452132_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000001298 120.0
HKD1_k127_1455323_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 370.0
HKD1_k127_1455323_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 356.0
HKD1_k127_1455323_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008951 267.0
HKD1_k127_1455323_3 chelatase, subunit chli K07391 - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
HKD1_k127_1455323_4 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000004361 151.0
HKD1_k127_1455323_6 Carboxypeptidase regulatory-like domain - - - 0.000000001141 67.0
HKD1_k127_1467771_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 6.75e-259 848.0
HKD1_k127_1467771_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000002419 172.0
HKD1_k127_1470726_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1189.0
HKD1_k127_1470726_1 periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004617 285.0
HKD1_k127_1470726_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004504 229.0
HKD1_k127_1470726_3 - - - - 0.0000000000000000000000000000000000000000000003165 173.0
HKD1_k127_1470726_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000001356 151.0
HKD1_k127_1489049_0 amino acid K03294 - - 3.352e-242 754.0
HKD1_k127_1489049_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 584.0
HKD1_k127_1489049_2 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 423.0
HKD1_k127_1489049_3 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000003661 264.0
HKD1_k127_1489049_4 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000001033 93.0
HKD1_k127_1489049_5 Aspartyl protease - - - 0.0000000000000001473 85.0
HKD1_k127_1489049_6 PFAM ABC transporter substrate binding protein K01989 - - 0.000357 50.0
HKD1_k127_1498021_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 463.0
HKD1_k127_1498021_1 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 398.0
HKD1_k127_1498021_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007304 253.0
HKD1_k127_1498021_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000007447 153.0
HKD1_k127_1498021_4 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000697 151.0
HKD1_k127_1498021_5 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000001112 116.0
HKD1_k127_1503752_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000003045 225.0
HKD1_k127_1503909_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 534.0
HKD1_k127_1503909_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 391.0
HKD1_k127_1503909_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 321.0
HKD1_k127_1504261_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 509.0
HKD1_k127_1504261_1 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000002021 178.0
HKD1_k127_1505257_0 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 369.0
HKD1_k127_1505257_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
HKD1_k127_1505257_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001687 240.0
HKD1_k127_1505257_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
HKD1_k127_1505257_4 COG1082 Sugar phosphate isomerases epimerases - - - 0.000000000000000000000000000000015 138.0
HKD1_k127_1505257_5 Domain of unknown function (DUF5011) - - - 0.00000000000000000000000000000005034 141.0
HKD1_k127_1505257_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000002027 133.0
HKD1_k127_1505257_7 Glycosyl transferase family 2 K20534 - - 0.0000000000000000002799 99.0
HKD1_k127_1514321_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000002917 182.0
HKD1_k127_1514321_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000005429 167.0
HKD1_k127_1514321_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000006441 72.0
HKD1_k127_1516992_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 377.0
HKD1_k127_1516992_1 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 297.0
HKD1_k127_1516992_2 COG0457 FOG TPR repeat - - - 0.0002166 52.0
HKD1_k127_1535633_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 345.0
HKD1_k127_1535633_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000001706 202.0
HKD1_k127_1535633_2 Hint domain - - - 0.000225 53.0
HKD1_k127_1538520_0 WD40-like Beta Propeller Repeat - - - 1.35e-286 902.0
HKD1_k127_1538520_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 632.0
HKD1_k127_1538520_2 IrrE N-terminal-like domain K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 542.0
HKD1_k127_1538520_3 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000102 237.0
HKD1_k127_1538520_4 ACT domain - - - 0.000000000000000000000000127 113.0
HKD1_k127_1538520_5 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000002913 103.0
HKD1_k127_1538520_6 COG0457 FOG TPR repeat - - - 0.0001598 51.0
HKD1_k127_1542451_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 415.0
HKD1_k127_1542451_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 370.0
HKD1_k127_1542451_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007119 271.0
HKD1_k127_1542451_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
HKD1_k127_1542451_4 - - - - 0.0000000000000000000000000000003922 127.0
HKD1_k127_1542451_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000004019 117.0
HKD1_k127_1542451_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000002268 119.0
HKD1_k127_1542451_7 DinB family - - - 0.000000000000000000007383 99.0
HKD1_k127_1549474_0 Zinc carboxypeptidase - - - 1.073e-198 651.0
HKD1_k127_1554843_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1043.0
HKD1_k127_1554843_1 - - - - 0.0000171 48.0
HKD1_k127_1556456_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 407.0
HKD1_k127_1556456_1 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 354.0
HKD1_k127_1556456_2 Peptidase M23 K21471 - - 0.000000000000000000000000000000000000395 147.0
HKD1_k127_1556456_3 - - - - 0.000000000000000000001594 101.0
HKD1_k127_1556456_4 Thioesterase superfamily - - - 0.000000000000002371 82.0
HKD1_k127_1556456_5 - - - - 0.000000000009348 72.0
HKD1_k127_1568932_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 454.0
HKD1_k127_1568932_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001638 289.0
HKD1_k127_1568932_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000002 113.0
HKD1_k127_1568932_3 RNA polymerase sigma factor K03088 - - 0.000000000000000000000001095 111.0
HKD1_k127_156944_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.995e-266 854.0
HKD1_k127_156944_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000002931 233.0
HKD1_k127_156944_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000001904 212.0
HKD1_k127_156944_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000002103 201.0
HKD1_k127_156944_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000002342 195.0
HKD1_k127_156944_5 Universal bacterial protein YeaZ K14742 - - 0.000000000000000000000000008794 124.0
HKD1_k127_156944_6 Rhodanese Homology Domain - - - 0.000000000000004193 89.0
HKD1_k127_156944_7 Protein of unknown function (DUF465) K09794 - - 0.000001101 58.0
HKD1_k127_1577905_0 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 378.0
HKD1_k127_1577905_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 361.0
HKD1_k127_1577905_2 penicillinase repressor - - - 0.000000001489 63.0
HKD1_k127_1607490_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000004199 190.0
HKD1_k127_1607490_2 ATPase family associated with various cellular activities (AAA) - - - 0.0001609 47.0
HKD1_k127_162252_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 493.0
HKD1_k127_162252_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001078 234.0
HKD1_k127_162252_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000008746 225.0
HKD1_k127_162252_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.000000000000000000000000000000000000000000001351 166.0
HKD1_k127_162252_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000008009 166.0
HKD1_k127_1624130_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 518.0
HKD1_k127_1624130_1 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000008276 225.0
HKD1_k127_1624130_2 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000002754 136.0
HKD1_k127_1624130_3 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000000000000000000001453 127.0
HKD1_k127_1629370_0 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 503.0
HKD1_k127_1629370_1 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000001234 200.0
HKD1_k127_1629370_2 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.0000000000000000000000000007615 115.0
HKD1_k127_1631111_0 4Fe-4S binding domain - - - 1.133e-261 821.0
HKD1_k127_1631111_1 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 452.0
HKD1_k127_1631111_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 431.0
HKD1_k127_1635481_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000001812 177.0
HKD1_k127_1635481_1 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000007357 107.0
HKD1_k127_1635481_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.000000000000004783 87.0
HKD1_k127_1651945_0 Belongs to the malate synthase family K01638 - 2.3.3.9 2.949e-230 726.0
HKD1_k127_1651945_1 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 9.388e-203 636.0
HKD1_k127_1651945_2 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 445.0
HKD1_k127_165417_0 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 616.0
HKD1_k127_165417_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 333.0
HKD1_k127_165417_2 GAF domain - - - 0.00000000000000000000000000000000000000000000000000001052 212.0
HKD1_k127_165417_3 TIGRFAM polymorphic outer membrane protein K21449 - - 0.0000000000000000000000000000000000000000001939 179.0
HKD1_k127_165417_4 Response regulator receiver domain - - - 0.00000000000000000008286 94.0
HKD1_k127_1674482_0 threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 336.0
HKD1_k127_1674482_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000504 297.0
HKD1_k127_1674482_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000001844 133.0
HKD1_k127_1674482_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000003862 89.0
HKD1_k127_1674482_4 Preprotein translocase SecG subunit K03075 - - 0.0000000000000006805 82.0
HKD1_k127_1674482_5 - - - - 0.0000000000007389 78.0
HKD1_k127_1674482_6 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000444 55.0
HKD1_k127_167924_0 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000001123 212.0
HKD1_k127_167924_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000588 169.0
HKD1_k127_167924_2 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000221 162.0
HKD1_k127_167924_3 Bacterial virulence protein (VirJ) - - - 0.0006689 46.0
HKD1_k127_1719977_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
HKD1_k127_1719977_1 Glycosyltransferase like family 2 K21366 - 2.4.1.122 0.00000000000000000000000000000000000000000000000000000000000004327 218.0
HKD1_k127_1719977_2 PilZ domain - - - 0.0000000000000000000000000000000008785 139.0
HKD1_k127_1719977_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000006571 126.0
HKD1_k127_1719977_4 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0007889 49.0
HKD1_k127_1735276_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 292.0
HKD1_k127_1735276_1 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000001208 201.0
HKD1_k127_1735276_2 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000000000003174 162.0
HKD1_k127_1735276_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.00000000000000000000000000000742 133.0
HKD1_k127_1754978_0 Bifunctional protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006729 263.0
HKD1_k127_1754978_1 Hexapeptide repeat of succinyl-transferase K00633 - 2.3.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 257.0
HKD1_k127_1754978_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K00980,K03272 - 2.7.1.167,2.7.7.39,2.7.7.70 0.0000000000000000000000000000000000000000000000001338 181.0
HKD1_k127_1754978_3 Psort location Cytoplasmic, score 8.96 K02841 - - 0.0000000000000000000000071 106.0
HKD1_k127_1754978_4 radical SAM domain protein - - - 0.00000002264 59.0
HKD1_k127_1760945_0 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000004871 124.0
HKD1_k127_1760945_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000002416 67.0
HKD1_k127_1766933_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000001198 251.0
HKD1_k127_1766933_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001354 243.0
HKD1_k127_1766933_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000004252 89.0
HKD1_k127_1766933_3 (FHA) domain - - - 0.000000000006337 75.0
HKD1_k127_1769818_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 355.0
HKD1_k127_1769818_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 359.0
HKD1_k127_1797431_0 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 548.0
HKD1_k127_1797431_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
HKD1_k127_1797431_2 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000000000008394 201.0
HKD1_k127_1797431_3 Peptidase M48 - - - 0.000000002779 62.0
HKD1_k127_1797431_4 Ankyrin repeats (many copies) - - - 0.000002163 59.0
HKD1_k127_1822778_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
HKD1_k127_1822778_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HKD1_k127_1822778_2 - - - - 0.0000000000000000000000000000000000000000000000202 178.0
HKD1_k127_1822778_3 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000003816 170.0
HKD1_k127_1828323_0 Binding-protein-dependent transport system inner membrane component K02050 - - 6.028e-218 690.0
HKD1_k127_1828323_1 C-terminal AAA-associated domain K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 528.0
HKD1_k127_1828323_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000001517 220.0
HKD1_k127_1828323_3 Histone deacetylase domain - - - 0.00000000000000002416 85.0
HKD1_k127_1837184_0 Belongs to the GPI family K01810 - 5.3.1.9 7.652e-258 802.0
HKD1_k127_1837184_1 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 412.0
HKD1_k127_1837184_2 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
HKD1_k127_1837184_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005129 266.0
HKD1_k127_1837184_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002602 244.0
HKD1_k127_1840759_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 561.0
HKD1_k127_1840759_1 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 406.0
HKD1_k127_1840759_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000171 275.0
HKD1_k127_1840759_3 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.00000000000000000000000000000000004367 138.0
HKD1_k127_1840759_4 Polysaccharide deacetylase - - - 0.000000000000000000000000006663 118.0
HKD1_k127_1840759_5 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000000003373 68.0
HKD1_k127_1852248_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.218e-250 792.0
HKD1_k127_1852248_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 593.0
HKD1_k127_1852248_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 479.0
HKD1_k127_1852248_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000001111 233.0
HKD1_k127_1852248_4 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000004859 199.0
HKD1_k127_1852248_5 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.000000000000000000000000000004504 123.0
HKD1_k127_1852248_6 Protein of unknown function (DUF1232) - - - 0.000000000000375 74.0
HKD1_k127_1852248_7 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.000001225 51.0
HKD1_k127_1862166_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 435.0
HKD1_k127_1862166_1 Histidine kinase - - - 0.00000000000000000000000000000000000008545 155.0
HKD1_k127_1862166_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000004056 64.0
HKD1_k127_1871738_0 Peptidase M14, carboxypeptidase A - - - 1.868e-275 879.0
HKD1_k127_1871738_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 3.3e-208 655.0
HKD1_k127_1871738_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
HKD1_k127_1871738_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 378.0
HKD1_k127_1871738_4 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000009803 160.0
HKD1_k127_1876958_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 346.0
HKD1_k127_1876958_1 IMP dehydrogenase activity K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
HKD1_k127_1876958_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000001153 130.0
HKD1_k127_1883023_0 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 482.0
HKD1_k127_1883023_1 Maltose O-acetyltransferase K00661 - 2.3.1.79 0.000002137 51.0
HKD1_k127_1885034_0 PFAM glycoside hydrolase family 39 - - - 2.331e-256 808.0
HKD1_k127_1885034_1 arylsulfatase activity - - - 0.0000000000000000000000000000005772 141.0
HKD1_k127_1891761_0 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 334.0
HKD1_k127_1891761_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000002884 191.0
HKD1_k127_1891761_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000002972 149.0
HKD1_k127_1891761_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000128 153.0
HKD1_k127_1891761_4 biosynthesis protein QueC K06920 - 6.3.4.20 0.000000000000000000000000000000000006095 144.0
HKD1_k127_1891761_5 FAD dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000005728 148.0
HKD1_k127_1891761_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00002173 48.0
HKD1_k127_1893529_0 PFAM ABC transporter related K06020 - 3.6.3.25 6.145e-291 899.0
HKD1_k127_1893529_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 493.0
HKD1_k127_1893529_2 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000008634 155.0
HKD1_k127_1893529_3 Hemerythrin HHE cation binding domain - - - 0.0000000000001874 76.0
HKD1_k127_1895343_0 succinyl-diaminopimelate desuccinylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 478.0
HKD1_k127_1895343_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 373.0
HKD1_k127_1895343_2 Ornithine cyclodeaminase/mu-crystallin family K21721 - 1.5.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 325.0
HKD1_k127_1895343_3 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000001293 192.0
HKD1_k127_1895343_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000005234 159.0
HKD1_k127_1895343_5 Peptidase M36 - - - 0.000000000000000152 92.0
HKD1_k127_1895343_6 cell adhesion involved in biofilm formation - - - 0.0000000000000007301 88.0
HKD1_k127_1901097_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K01534 - 3.2.1.68,3.6.3.3,3.6.3.5 9.149e-244 771.0
HKD1_k127_1901097_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 306.0
HKD1_k127_1901097_2 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000002178 203.0
HKD1_k127_1901097_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000001576 114.0
HKD1_k127_1907750_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 5.169e-204 653.0
HKD1_k127_1907750_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 437.0
HKD1_k127_1907750_2 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 370.0
HKD1_k127_1907750_3 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 330.0
HKD1_k127_1907750_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000001976 237.0
HKD1_k127_1907750_5 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.000000000000000008231 84.0
HKD1_k127_1907750_6 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.000002612 57.0
HKD1_k127_1907946_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 278.0
HKD1_k127_1907946_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007925 248.0
HKD1_k127_1907946_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000425 169.0
HKD1_k127_1907946_3 Predicted membrane protein (DUF2127) - - - 0.00003355 52.0
HKD1_k127_1916293_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 341.0
HKD1_k127_1916293_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000003211 244.0
HKD1_k127_1916293_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000003953 208.0
HKD1_k127_1916293_3 Prokaryotic RING finger family 1 - - - 0.00000004035 61.0
HKD1_k127_1917555_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 483.0
HKD1_k127_1917555_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001889 278.0
HKD1_k127_1917555_2 RNA-binding protein - - - 0.0000000000000000000000002383 108.0
HKD1_k127_1937846_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001891 229.0
HKD1_k127_1937846_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000001111 123.0
HKD1_k127_1937846_2 - - - - 0.000003923 56.0
HKD1_k127_194745_0 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000001569 156.0
HKD1_k127_194745_1 Protein tyrosine kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000001652 120.0
HKD1_k127_1955112_0 serine-type peptidase activity K01303 - 3.4.19.1 9.052e-265 827.0
HKD1_k127_1955112_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 462.0
HKD1_k127_1955112_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 402.0
HKD1_k127_1955112_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005416 284.0
HKD1_k127_1955112_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000006991 195.0
HKD1_k127_1955112_5 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000005664 124.0
HKD1_k127_1955112_7 zinc-ribbon domain - - - 0.00000000005213 74.0
HKD1_k127_1957976_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 297.0
HKD1_k127_1957976_1 denitrification pathway - - - 0.0000000000000000000000000002309 122.0
HKD1_k127_1957976_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000001629 78.0
HKD1_k127_1957976_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000001501 64.0
HKD1_k127_1957976_5 - - - - 0.0000002108 64.0
HKD1_k127_1959151_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000008252 183.0
HKD1_k127_1959151_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0007807 45.0
HKD1_k127_1971483_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 7.988e-265 831.0
HKD1_k127_1971483_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 499.0
HKD1_k127_1971483_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000006328 144.0
HKD1_k127_1971483_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000007848 70.0
HKD1_k127_1971483_4 acyl carrier protein - - - 0.000000000008741 69.0
HKD1_k127_1971483_5 - - - - 0.0005913 44.0
HKD1_k127_1972435_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.201e-301 951.0
HKD1_k127_1972435_1 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000000001293 160.0
HKD1_k127_1972435_2 RDD family - - - 0.0000000000000007648 90.0
HKD1_k127_1972435_3 Tetratricopeptide repeat - - - 0.0000000000009191 81.0
HKD1_k127_1972435_4 PrcB C-terminal - - - 0.000002907 56.0
HKD1_k127_1973555_0 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
HKD1_k127_1973555_1 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003313 252.0
HKD1_k127_1980167_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.791e-267 839.0
HKD1_k127_1980167_1 PFAM GCN5-related N-acetyltransferase (GNAT) domain - - - 0.00000000000000005269 81.0
HKD1_k127_198683_0 Involved in the tonB-independent uptake of proteins - - - 8.911e-203 660.0
HKD1_k127_198683_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 511.0
HKD1_k127_198683_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000008573 217.0
HKD1_k127_198683_3 - - - - 0.000000000000000227 81.0
HKD1_k127_198683_4 Domain of unknown function (DUF4440) - - - 0.000008922 53.0
HKD1_k127_1987703_0 Glycosyltransferase like family 2 K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 613.0
HKD1_k127_1987703_1 Wzt C-terminal domain K01990 - - 0.000000000000000000000000000000000000000000000000000000005429 209.0
HKD1_k127_1997211_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1667.0
HKD1_k127_1997211_1 radical SAM domain protein - - - 1.663e-219 690.0
HKD1_k127_1997211_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 478.0
HKD1_k127_1997211_3 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000002706 198.0
HKD1_k127_1997211_4 HlyD membrane-fusion protein of T1SS K03585 - - 0.0000000000000000000000000000000000000000000000000000004007 195.0
HKD1_k127_2001363_0 DNA polymerase K02337,K14162 - 2.7.7.7 1.032e-221 724.0
HKD1_k127_2001363_1 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 565.0
HKD1_k127_2001363_10 carboxylic ester hydrolase activity - - - 0.0000000000000000000001197 109.0
HKD1_k127_2001363_11 nickel cation binding K03189,K04652 - - 0.000000000000005458 74.0
HKD1_k127_2001363_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
HKD1_k127_2001363_3 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 388.0
HKD1_k127_2001363_4 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007971 280.0
HKD1_k127_2001363_5 nickel cation binding K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000001567 192.0
HKD1_k127_2001363_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000004271 186.0
HKD1_k127_2001363_7 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000000000000000000000000000000000002528 176.0
HKD1_k127_2001363_8 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000001003 161.0
HKD1_k127_2001363_9 Winged helix DNA-binding domain - - - 0.0000000000000000000000001106 112.0
HKD1_k127_2008916_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000008789 236.0
HKD1_k127_2008916_1 Oxygen tolerance - - - 0.000000000000000000003226 107.0
HKD1_k127_2008916_2 von Willebrand factor, type A K07114 - - 0.00001268 57.0
HKD1_k127_2013051_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 337.0
HKD1_k127_2013051_1 - - - - 0.0000000000000000000000000000000000000000253 174.0
HKD1_k127_2016590_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.144e-264 825.0
HKD1_k127_2016590_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 563.0
HKD1_k127_2016590_2 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001365 264.0
HKD1_k127_2016590_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000003223 227.0
HKD1_k127_2016590_4 Peptidase A24 K02654 - 3.4.23.43 0.00000000000000000000000002016 113.0
HKD1_k127_2035540_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000006682 246.0
HKD1_k127_2035540_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000002315 240.0
HKD1_k127_2035540_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000007159 233.0
HKD1_k127_2035540_3 Putative ABC-transporter type IV - - - 0.000000000000000000000000000000000009018 140.0
HKD1_k127_2035540_4 positive regulation of translation, ncRNA-mediated K03666 - - 0.0000000000000000000000000002106 119.0
HKD1_k127_2035540_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000272 106.0
HKD1_k127_2035540_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000004284 84.0
HKD1_k127_2040027_0 PFAM ABC transporter transmembrane K06147 - - 9.878e-274 852.0
HKD1_k127_2040027_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 616.0
HKD1_k127_2052078_0 Belongs to the peptidase S16 family - - - 1.306e-309 967.0
HKD1_k127_2052078_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 616.0
HKD1_k127_2052078_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 485.0
HKD1_k127_2052078_3 PFAM AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
HKD1_k127_2052078_4 HupF/HypC family K04653 - - 0.000000000000000000003126 99.0
HKD1_k127_2052078_5 Uncharacterized conserved protein (DUF2249) - - - 0.000002417 53.0
HKD1_k127_2052078_7 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0006157 42.0
HKD1_k127_2052078_8 carbon dioxide binding K04653 - - 0.0006648 44.0
HKD1_k127_2052461_0 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 349.0
HKD1_k127_2052461_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000001236 147.0
HKD1_k127_2052461_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000006282 71.0
HKD1_k127_2065942_0 PFAM Curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000009557 143.0
HKD1_k127_2065942_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000114 125.0
HKD1_k127_2065942_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000001707 79.0
HKD1_k127_2072946_0 PFAM histone deacetylase superfamily K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 391.0
HKD1_k127_2072946_1 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000002229 215.0
HKD1_k127_2072946_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000003949 128.0
HKD1_k127_2072946_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000008123 65.0
HKD1_k127_2079391_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 514.0
HKD1_k127_2079391_1 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000004955 241.0
HKD1_k127_2079391_2 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
HKD1_k127_2079391_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000001078 190.0
HKD1_k127_2086015_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 319.0
HKD1_k127_2086015_1 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 334.0
HKD1_k127_2086015_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
HKD1_k127_2086015_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
HKD1_k127_2086015_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000006316 184.0
HKD1_k127_2086015_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000002273 161.0
HKD1_k127_2092079_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 330.0
HKD1_k127_2092079_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
HKD1_k127_2092079_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
HKD1_k127_2092079_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000001288 208.0
HKD1_k127_2092079_4 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000772 196.0
HKD1_k127_2092079_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000002642 138.0
HKD1_k127_2092079_6 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000009003 53.0
HKD1_k127_2100588_0 serine-type peptidase activity K01278 - 3.4.14.5 6.302e-224 715.0
HKD1_k127_2100588_1 von Willebrand factor, type A - - - 0.000000003525 66.0
HKD1_k127_2101486_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 512.0
HKD1_k127_2101486_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 488.0
HKD1_k127_2101486_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 439.0
HKD1_k127_2101486_3 positive regulation of growth rate - - - 0.000000000000000000000000000000001578 145.0
HKD1_k127_2101486_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000001426 143.0
HKD1_k127_2101486_5 TIGRFAM TonB family protein K03832 - - 0.00000000006589 76.0
HKD1_k127_2104855_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 601.0
HKD1_k127_2104855_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 340.0
HKD1_k127_2104855_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 317.0
HKD1_k127_2104855_3 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
HKD1_k127_2104855_4 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000005888 214.0
HKD1_k127_2104855_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000001083 167.0
HKD1_k127_2104855_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000004844 109.0
HKD1_k127_2104855_7 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000004461 109.0
HKD1_k127_2104855_8 Ribosomal L32p protein family K02911 - - 0.00000000000000000004402 90.0
HKD1_k127_2122237_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000006526 222.0
HKD1_k127_2122237_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000001566 178.0
HKD1_k127_2122237_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000001609 153.0
HKD1_k127_2122237_3 Amidinotransferase - - - 0.000000000000000000000000006473 124.0
HKD1_k127_2139909_0 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 389.0
HKD1_k127_2139909_1 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 360.0
HKD1_k127_2139909_2 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 305.0
HKD1_k127_2139909_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
HKD1_k127_2139909_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000002059 221.0
HKD1_k127_2139909_5 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000871 199.0
HKD1_k127_2139909_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000001692 189.0
HKD1_k127_2139909_7 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001417 186.0
HKD1_k127_2139909_8 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000001307 99.0
HKD1_k127_2139909_9 SNARE associated Golgi protein - - - 0.0000000003413 61.0
HKD1_k127_2140507_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 447.0
HKD1_k127_2140507_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 328.0
HKD1_k127_2140507_2 Peptidase family M50 - - - 0.00000000000000000000009116 101.0
HKD1_k127_2151779_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 1.136e-203 643.0
HKD1_k127_2151779_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 499.0
HKD1_k127_2151779_2 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004869 258.0
HKD1_k127_2151779_3 ig-like, plexins, transcription factors - - - 0.00000000000000000000000000000003682 142.0
HKD1_k127_2151779_4 PBS lyase HEAT-like repeat - - - 0.00000000001652 77.0
HKD1_k127_2151779_5 Histidine kinase K02491 - 2.7.13.3 0.00000009584 54.0
HKD1_k127_2159305_0 racemase activity, acting on amino acids and derivatives K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 308.0
HKD1_k127_2159305_1 membrane - - - 0.0000000000000000000000000000000001787 138.0
HKD1_k127_2159305_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000002655 140.0
HKD1_k127_2159305_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0003276 44.0
HKD1_k127_216103_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000001682 197.0
HKD1_k127_216103_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000005056 130.0
HKD1_k127_216103_2 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000000215 115.0
HKD1_k127_216103_3 transcriptional regulator - - - 0.000000000000000000000000242 109.0
HKD1_k127_2166869_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 451.0
HKD1_k127_2166869_1 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000001378 159.0
HKD1_k127_2166869_2 helix_turn_helix, mercury resistance - - - 0.000000000000000000004329 98.0
HKD1_k127_2168183_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 512.0
HKD1_k127_2168183_1 Mismatch repair ATPase (MutS family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 506.0
HKD1_k127_2168183_2 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 422.0
HKD1_k127_2168183_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 364.0
HKD1_k127_2168183_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 289.0
HKD1_k127_2168183_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
HKD1_k127_2168183_6 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 256.0
HKD1_k127_2168183_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000003402 106.0
HKD1_k127_2172847_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 518.0
HKD1_k127_2172847_1 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 406.0
HKD1_k127_2172847_2 Cytochrome c K00413 - - 0.000000000000000000000000000000000000001715 162.0
HKD1_k127_2172847_3 Barstar (barnase inhibitor) - - - 0.00000000000000000000000003822 113.0
HKD1_k127_2172847_4 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000001214 106.0
HKD1_k127_2179401_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000006075 164.0
HKD1_k127_2179401_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000001056 104.0
HKD1_k127_2179401_2 Ion channel - - - 0.0000000000005744 72.0
HKD1_k127_2184166_0 Male sterility protein K01897 - 6.2.1.3 3.117e-313 995.0
HKD1_k127_2184166_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 362.0
HKD1_k127_2184166_2 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002717 262.0
HKD1_k127_218483_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.00000000000000000000000000000000000000000000000000000000289 224.0
HKD1_k127_218483_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000003052 79.0
HKD1_k127_218483_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000001111 83.0
HKD1_k127_2192785_0 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 401.0
HKD1_k127_2192785_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 336.0
HKD1_k127_2192785_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000003808 244.0
HKD1_k127_2196671_0 cellulose binding - - - 4.644e-265 847.0
HKD1_k127_2196671_1 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 349.0
HKD1_k127_2196671_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000000000003127 138.0
HKD1_k127_2220860_0 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004377 278.0
HKD1_k127_2220860_1 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000002567 145.0
HKD1_k127_222729_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 8.399e-201 646.0
HKD1_k127_222729_1 NADH flavin K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 622.0
HKD1_k127_222729_2 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
HKD1_k127_222729_3 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000001399 222.0
HKD1_k127_222729_4 peroxiredoxin activity - - - 0.00000000000000000000000000000001826 131.0
HKD1_k127_222729_5 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000004893 91.0
HKD1_k127_2230009_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 535.0
HKD1_k127_2230009_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 378.0
HKD1_k127_2230009_2 - - - - 0.00002057 55.0
HKD1_k127_2231673_0 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000003439 125.0
HKD1_k127_2231673_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000948 89.0
HKD1_k127_2233561_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 329.0
HKD1_k127_2233561_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 292.0
HKD1_k127_2233561_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004128 282.0
HKD1_k127_2233561_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000002813 213.0
HKD1_k127_2233561_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000368 123.0
HKD1_k127_2233561_5 Acetyltransferase (GNAT) family - - - 0.000000006584 59.0
HKD1_k127_2235230_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 326.0
HKD1_k127_2235230_1 Domain of unknown function (DUF4261) - - - 0.00000000000000000000000000000000000000000000000001917 189.0
HKD1_k127_2235230_2 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.000000000000000000000000000000000000000000001827 183.0
HKD1_k127_2235230_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000008683 128.0
HKD1_k127_2235230_4 DinB superfamily - - - 0.00000000000000000002516 94.0
HKD1_k127_2235230_5 SnoaL-like domain - - - 0.0005024 51.0
HKD1_k127_2244911_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 322.0
HKD1_k127_2244911_1 DNA ligase D, 3'-phosphoesterase domain - - - 0.000000000000000000000000000000000000000000001391 169.0
HKD1_k127_2244911_2 - - - - 0.00000004443 58.0
HKD1_k127_2244911_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000006228 54.0
HKD1_k127_2245411_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 429.0
HKD1_k127_2245411_1 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 397.0
HKD1_k127_2245411_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 317.0
HKD1_k127_2245411_3 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000003977 224.0
HKD1_k127_2245411_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000003735 192.0
HKD1_k127_2245411_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000005692 187.0
HKD1_k127_2245411_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000001058 98.0
HKD1_k127_2245411_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00007344 45.0
HKD1_k127_2247255_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 489.0
HKD1_k127_2247255_1 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 471.0
HKD1_k127_2247255_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000002261 162.0
HKD1_k127_2247255_3 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000002997 139.0
HKD1_k127_2247255_4 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000001829 125.0
HKD1_k127_2247255_5 - - - - 0.00000001317 64.0
HKD1_k127_2263099_0 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
HKD1_k127_2263099_1 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000002209 169.0
HKD1_k127_226408_0 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000005998 230.0
HKD1_k127_226408_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000005213 138.0
HKD1_k127_226408_2 PFAM GGDEF domain containing protein - - - 0.0001754 45.0
HKD1_k127_2264686_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 422.0
HKD1_k127_2264686_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 330.0
HKD1_k127_2264686_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002091 165.0
HKD1_k127_2264686_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000002093 128.0
HKD1_k127_2264686_4 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.0000000000000000000001274 115.0
HKD1_k127_2264686_5 LytTr DNA-binding domain K02477 - - 0.00000000000003301 73.0
HKD1_k127_2264686_6 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000001757 68.0
HKD1_k127_2269825_0 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 430.0
HKD1_k127_2269825_1 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 326.0
HKD1_k127_2269825_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HKD1_k127_2269825_3 - - - - 0.0000000000000000000000000000000000000000000000000000000003648 229.0
HKD1_k127_2269825_4 nitric oxide dioxygenase activity - - - 0.000000000000000000000008439 103.0
HKD1_k127_2269825_5 Peptidase inhibitor I9 K14645 - - 0.000000000001904 81.0
HKD1_k127_2290483_0 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 470.0
HKD1_k127_2290483_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 347.0
HKD1_k127_2290483_2 - - - - 0.00000000000007186 85.0
HKD1_k127_2290483_3 - - - - 0.00005706 49.0
HKD1_k127_2307588_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.435e-225 730.0
HKD1_k127_2307588_1 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 368.0
HKD1_k127_2307588_10 General transcription factor 3C polypeptide K15201 - - 0.0006713 53.0
HKD1_k127_2307588_11 - - - - 0.0007318 42.0
HKD1_k127_2307588_2 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001782 256.0
HKD1_k127_2307588_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HKD1_k127_2307588_4 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000003733 226.0
HKD1_k127_2307588_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000002964 154.0
HKD1_k127_2307588_6 Regulatory protein - - - 0.00000000000000000000000141 108.0
HKD1_k127_2307588_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000001687 104.0
HKD1_k127_2307588_8 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000001437 80.0
HKD1_k127_2307588_9 - - - - 0.000000248 53.0
HKD1_k127_2312913_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 5.53e-295 922.0
HKD1_k127_2312913_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 511.0
HKD1_k127_2312913_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 497.0
HKD1_k127_2312913_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
HKD1_k127_2312913_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000005122 168.0
HKD1_k127_2312913_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000007858 120.0
HKD1_k127_2313527_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 413.0
HKD1_k127_2313527_1 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 340.0
HKD1_k127_2313527_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000006803 172.0
HKD1_k127_2321768_0 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005219 282.0
HKD1_k127_2321768_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000416 269.0
HKD1_k127_2321768_10 subunit of a heme lyase K02200 - - 0.000000000000000531 85.0
HKD1_k127_2321768_11 - - - - 0.000000000001482 70.0
HKD1_k127_2321768_2 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000008048 264.0
HKD1_k127_2321768_3 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000002257 227.0
HKD1_k127_2321768_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000006024 189.0
HKD1_k127_2321768_5 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000001742 171.0
HKD1_k127_2321768_6 domain, Protein - - - 0.0000000000000000000000000000000000000000002059 180.0
HKD1_k127_2321768_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000003034 151.0
HKD1_k127_2321768_8 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 - - 0.0000000000000000000000000000004824 130.0
HKD1_k127_2321768_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000001204 91.0
HKD1_k127_2329506_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000002733 221.0
HKD1_k127_2329506_1 response regulator, receiver K03413 - - 0.000000000000000000000000000000000000000001009 160.0
HKD1_k127_2329506_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000182 147.0
HKD1_k127_2329506_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000003074 134.0
HKD1_k127_2329506_4 Two component signalling adaptor domain - - - 0.00000001095 63.0
HKD1_k127_2332290_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 451.0
HKD1_k127_2332290_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
HKD1_k127_2332290_2 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000000000001336 199.0
HKD1_k127_2332290_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000005924 100.0
HKD1_k127_2336411_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000001598 100.0
HKD1_k127_234121_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 527.0
HKD1_k127_234121_1 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 447.0
HKD1_k127_234121_2 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 345.0
HKD1_k127_234121_3 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
HKD1_k127_234121_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000004931 205.0
HKD1_k127_234121_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000631 156.0
HKD1_k127_234121_6 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000000003708 119.0
HKD1_k127_2346662_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 476.0
HKD1_k127_2346662_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 417.0
HKD1_k127_2346662_2 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.0000000000000000000000000000000000000000000007712 183.0
HKD1_k127_2346662_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000008556 146.0
HKD1_k127_2346662_4 Transcriptional regulator K07506 - - 0.0000000000000000000000000000000959 137.0
HKD1_k127_2346662_5 - - - - 0.000000000002222 78.0
HKD1_k127_2346662_6 protein-disulfide reductase activity - - - 0.0000000987 60.0
HKD1_k127_2346662_7 Putative peptidoglycan binding domain - - - 0.0002197 53.0
HKD1_k127_2368377_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.672e-316 982.0
HKD1_k127_2368377_1 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000003762 222.0
HKD1_k127_2368377_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000003101 208.0
HKD1_k127_2368377_3 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000001357 164.0
HKD1_k127_2368377_4 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000946 132.0
HKD1_k127_2368377_5 Alpha beta hydrolase - - - 0.00000000000000000007148 96.0
HKD1_k127_2368377_6 Methyltransferase domain - - - 0.00009677 52.0
HKD1_k127_237684_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001293 250.0
HKD1_k127_237684_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000008584 216.0
HKD1_k127_237684_2 - - - - 0.00000000000000000000000000000000000000001262 166.0
HKD1_k127_237684_3 lipoprotein localization to outer membrane - - - 0.0000000000000000000000000000006328 127.0
HKD1_k127_2380997_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000009818 157.0
HKD1_k127_2380997_1 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000652 136.0
HKD1_k127_2385209_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 544.0
HKD1_k127_2385209_1 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 450.0
HKD1_k127_2385209_2 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 373.0
HKD1_k127_2385209_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 361.0
HKD1_k127_2385209_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000004287 205.0
HKD1_k127_2385209_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000001558 176.0
HKD1_k127_2397215_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 610.0
HKD1_k127_2397215_1 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 464.0
HKD1_k127_2397215_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 440.0
HKD1_k127_2397215_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 424.0
HKD1_k127_2397215_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002159 240.0
HKD1_k127_2397215_5 DinB superfamily K07552 - - 0.000000000000000144 81.0
HKD1_k127_2397215_6 DinB superfamily K07552 - - 0.000000000000002735 78.0
HKD1_k127_2399102_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 381.0
HKD1_k127_2399102_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 372.0
HKD1_k127_2399102_2 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 352.0
HKD1_k127_2399102_3 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001109 188.0
HKD1_k127_2399102_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000882 162.0
HKD1_k127_2399102_5 - - - - 0.00000000000000000000000000000000000005608 156.0
HKD1_k127_240971_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 381.0
HKD1_k127_240971_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000003311 196.0
HKD1_k127_240971_2 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000008243 179.0
HKD1_k127_240971_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000006827 152.0
HKD1_k127_240971_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000006692 116.0
HKD1_k127_240971_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000001381 97.0
HKD1_k127_240971_6 Glycosyltransferase Family 4 - - - 0.0000000007142 65.0
HKD1_k127_2412594_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 405.0
HKD1_k127_2412594_1 Abc transporter K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 307.0
HKD1_k127_2412594_2 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000135 220.0
HKD1_k127_2412594_3 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.000000000000000000000000000000000000000000000000000002447 198.0
HKD1_k127_2412594_4 Domain of unknown function (DUF4214) - - - 0.0000000000000000000000000000000000000000000005076 187.0
HKD1_k127_2412594_5 - - - - 0.00000000000000000000000002904 113.0
HKD1_k127_2412594_6 methyltransferase K02169 - 2.1.1.197 0.00000001421 68.0
HKD1_k127_2428738_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 380.0
HKD1_k127_2428738_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 319.0
HKD1_k127_2428738_2 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004348 277.0
HKD1_k127_2428738_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003968 271.0
HKD1_k127_2431867_0 Polyphosphate kinase 2 (PPK2) - - - 5.366e-208 657.0
HKD1_k127_2431867_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 353.0
HKD1_k127_2431867_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
HKD1_k127_2431867_3 - - - - 0.000000000000001172 91.0
HKD1_k127_2443055_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000001062 244.0
HKD1_k127_2443055_1 -O-antigen K02847,K13009 - - 0.0000000000008586 81.0
HKD1_k127_2460434_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 374.0
HKD1_k127_2460434_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001515 272.0
HKD1_k127_2460434_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000001421 235.0
HKD1_k127_2460434_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000004892 169.0
HKD1_k127_2460434_4 LmbE family - - - 0.00000000000000000000000000000000228 134.0
HKD1_k127_2460434_5 oxidoreductase activity - - - 0.00000000007788 74.0
HKD1_k127_2490379_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.173e-246 775.0
HKD1_k127_2490379_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
HKD1_k127_2490379_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 339.0
HKD1_k127_2490379_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000001645 195.0
HKD1_k127_2490379_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000001798 138.0
HKD1_k127_2490379_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000002711 79.0
HKD1_k127_249286_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 618.0
HKD1_k127_249286_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 582.0
HKD1_k127_249286_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 566.0
HKD1_k127_249286_3 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 455.0
HKD1_k127_250574_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HKD1_k127_250574_1 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 310.0
HKD1_k127_250574_2 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001854 284.0
HKD1_k127_250574_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000008323 243.0
HKD1_k127_250574_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000005534 130.0
HKD1_k127_2506016_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 525.0
HKD1_k127_2506016_1 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
HKD1_k127_2506016_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.00000000000000000000000000437 117.0
HKD1_k127_2506016_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 328.0
HKD1_k127_2506016_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
HKD1_k127_2506016_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004159 269.0
HKD1_k127_2506016_5 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002982 261.0
HKD1_k127_2506016_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
HKD1_k127_2506016_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000008443 184.0
HKD1_k127_2506016_9 - - - - 0.0000000000000000000000000000000000000000002035 164.0
HKD1_k127_2518626_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 497.0
HKD1_k127_2518626_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000509 243.0
HKD1_k127_2518626_2 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000000000000000000000001211 165.0
HKD1_k127_2573125_0 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 398.0
HKD1_k127_2573125_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 334.0
HKD1_k127_2573125_2 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 328.0
HKD1_k127_2573125_3 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
HKD1_k127_2580723_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 307.0
HKD1_k127_2580723_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000006452 188.0
HKD1_k127_2580723_2 TPR repeat - - - 0.00000000000001943 84.0
HKD1_k127_2582797_0 ApbE family K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
HKD1_k127_2582797_1 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007744 253.0
HKD1_k127_2582797_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000001513 173.0
HKD1_k127_2582797_3 Redoxin - - - 0.000000000000000000000000000000000559 139.0
HKD1_k127_2591554_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 436.0
HKD1_k127_2591554_1 Preprotein translocase subunit K03210 - - 0.0000000000004221 73.0
HKD1_k127_2591554_2 ubiE/COQ5 methyltransferase family - - - 0.000000000001452 76.0
HKD1_k127_2618672_0 cellulose binding - - - 0.0 1056.0
HKD1_k127_2618672_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000011 243.0
HKD1_k127_2634051_1 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000001289 111.0
HKD1_k127_2634051_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000005559 112.0
HKD1_k127_2634051_3 Stage II sporulation D domain protein K06381 - - 0.000000000000001604 87.0
HKD1_k127_2686197_0 ig-like, plexins, transcription factors - - - 0.000003699 59.0
HKD1_k127_2688510_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 364.0
HKD1_k127_2688510_1 Acts as a magnesium transporter K04767,K06213,K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000007842 231.0
HKD1_k127_2688510_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.000177 55.0
HKD1_k127_271912_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.077e-245 774.0
HKD1_k127_271912_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000002406 179.0
HKD1_k127_271912_2 Methyltransferase domain - - - 0.000000000000000002551 89.0
HKD1_k127_2727631_0 Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 364.0
HKD1_k127_2727631_1 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 317.0
HKD1_k127_2727631_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000244 197.0
HKD1_k127_2727631_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000001352 151.0
HKD1_k127_2727631_4 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000002137 87.0
HKD1_k127_2727631_5 antisigma factor binding K04749 - - 0.000001456 54.0
HKD1_k127_2736193_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 376.0
HKD1_k127_2736193_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001974 277.0
HKD1_k127_2736193_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000001657 189.0
HKD1_k127_2736193_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000003467 176.0
HKD1_k127_2736193_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000002025 183.0
HKD1_k127_2736193_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000002478 153.0
HKD1_k127_2739861_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 373.0
HKD1_k127_2739861_1 Elongator protein 3, MiaB family, Radical SAM K06871,K21936 - 2.1.1.342 0.00000000000000000000000000000000000000000000001802 187.0
HKD1_k127_2739861_2 radical SAM K07129 - - 0.00000000000000000000000000000000657 141.0
HKD1_k127_2739861_3 DNA-templated transcription, initiation K03088,K03091 - - 0.000000000000000000000000000001188 129.0
HKD1_k127_2739861_4 oxidoreductase activity - - - 0.0003345 53.0
HKD1_k127_2764876_0 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000003194 164.0
HKD1_k127_2764876_1 KWG Leptospira - - - 0.0000000000000000009833 93.0
HKD1_k127_2764876_2 PFAM PKD domain containing protein - - - 0.00000003705 63.0
HKD1_k127_2772057_0 Histidine Phosphotransfer domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 355.0
HKD1_k127_2772057_1 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000008018 111.0
HKD1_k127_2772057_2 antisigma factor binding K02066,K04749 - - 0.00000000000000000008651 94.0
HKD1_k127_279619_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000003614 172.0
HKD1_k127_279619_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000003703 145.0
HKD1_k127_2801037_0 DinB family - - - 0.000000000000000000007119 98.0
HKD1_k127_2801037_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K04764 - - 0.00000000000000000007797 92.0
HKD1_k127_2801037_2 AntiSigma factor K12132 - 2.7.11.1 0.000000000000005069 89.0
HKD1_k127_2801037_3 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000007422 82.0
HKD1_k127_2801037_4 peptidyl-tyrosine sulfation - - - 0.0004078 53.0
HKD1_k127_2804452_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.101e-238 753.0
HKD1_k127_2804452_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008668 277.0
HKD1_k127_2804452_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000003397 186.0
HKD1_k127_2804452_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000001134 111.0
HKD1_k127_2806213_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 465.0
HKD1_k127_2815840_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.614e-267 842.0
HKD1_k127_2818442_0 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 386.0
HKD1_k127_2818442_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008731 291.0
HKD1_k127_2818442_2 methyltransferase - - - 0.000000000000000000000000000000002982 139.0
HKD1_k127_2818442_3 PAP2 superfamily - - - 0.0000000000003197 72.0
HKD1_k127_2820205_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 299.0
HKD1_k127_2820205_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000005587 262.0
HKD1_k127_2820205_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HKD1_k127_2820205_3 PFAM Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000001295 156.0
HKD1_k127_2824709_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 570.0
HKD1_k127_2824709_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 422.0
HKD1_k127_2824709_10 - - - - 0.000000000000000000003223 101.0
HKD1_k127_2824709_11 - - - - 0.00000000000000000002759 95.0
HKD1_k127_2824709_12 BNR Asp-box repeat - - - 0.0000000001148 75.0
HKD1_k127_2824709_13 Cupredoxin-like domain - - - 0.00000004153 66.0
HKD1_k127_2824709_14 - - - - 0.000008954 52.0
HKD1_k127_2824709_15 - - - - 0.0008605 49.0
HKD1_k127_2824709_2 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 408.0
HKD1_k127_2824709_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 288.0
HKD1_k127_2824709_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007341 249.0
HKD1_k127_2824709_5 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000001336 154.0
HKD1_k127_2824709_6 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000004893 133.0
HKD1_k127_2824709_7 - K01865 - 5.4.4.1 0.00000000000000000000000000004079 124.0
HKD1_k127_2824709_8 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000001158 124.0
HKD1_k127_2824709_9 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000002066 116.0
HKD1_k127_2830808_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 330.0
HKD1_k127_2832884_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000159 287.0
HKD1_k127_2832884_1 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000956 167.0
HKD1_k127_2832884_2 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000025 119.0
HKD1_k127_2853081_0 Dienelactone hydrolase family - - - 3.351e-238 755.0
HKD1_k127_2853081_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 5.763e-236 745.0
HKD1_k127_2853081_2 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 348.0
HKD1_k127_2853081_3 Virulence protein - - - 0.000000000000000000000000000000000000000000000000000000001728 208.0
HKD1_k127_285559_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 390.0
HKD1_k127_285559_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 332.0
HKD1_k127_285559_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001629 283.0
HKD1_k127_285559_3 Carboxypeptidase regulatory-like domain - - - 0.0000009202 58.0
HKD1_k127_2863548_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000006471 257.0
HKD1_k127_2863548_1 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
HKD1_k127_2863548_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000003387 194.0
HKD1_k127_2863548_3 Membrane complex biogenesis protein, BtpA family K06971 - - 0.0000000000000000000000000000000000000000001682 173.0
HKD1_k127_2863548_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000003448 130.0
HKD1_k127_2866503_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.994e-284 887.0
HKD1_k127_2866503_1 PFAM band 7 protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 384.0
HKD1_k127_2866503_2 prohibitin homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000001791 169.0
HKD1_k127_2866503_3 PFAM Prolyl oligopeptidase family - - - 0.000002515 51.0
HKD1_k127_2894801_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 393.0
HKD1_k127_2894801_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 286.0
HKD1_k127_2894801_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001146 227.0
HKD1_k127_2894801_3 Peptidase M50B-like - - - 0.0000000000000000000000000000000000000007367 154.0
HKD1_k127_2894801_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000136 84.0
HKD1_k127_2894801_5 Putative adhesin - - - 0.000004646 59.0
HKD1_k127_2894864_0 lysine biosynthetic process via aminoadipic acid - - - 1.496e-271 862.0
HKD1_k127_2894864_1 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 541.0
HKD1_k127_2894864_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 409.0
HKD1_k127_2894864_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 352.0
HKD1_k127_2894864_4 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 271.0
HKD1_k127_2894864_5 ABC-type spermidine putrescine transport system, permease component II K02053,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000588 246.0
HKD1_k127_2894864_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001852 179.0
HKD1_k127_2894864_7 PFAM response regulator receiver K02477 - - 0.0000000000000000000000004361 108.0
HKD1_k127_2894864_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000007614 72.0
HKD1_k127_2900976_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 376.0
HKD1_k127_2900976_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000001336 166.0
HKD1_k127_2900976_2 Transcriptional regulator, BadM Rrf2 family K13643 - - 0.0000000000000000002638 94.0
HKD1_k127_2900976_3 YwiC-like protein - - - 0.0000000000000001091 90.0
HKD1_k127_2909809_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 392.0
HKD1_k127_2909809_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001424 275.0
HKD1_k127_2909809_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000009945 144.0
HKD1_k127_2920532_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 536.0
HKD1_k127_2920532_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 554.0
HKD1_k127_2920532_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 481.0
HKD1_k127_2920532_3 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 468.0
HKD1_k127_2920532_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
HKD1_k127_2920532_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 369.0
HKD1_k127_2920532_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 302.0
HKD1_k127_2920532_7 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000001341 112.0
HKD1_k127_2920532_8 ATP-binding protein K04562 - - 0.000000000000000000000004353 116.0
HKD1_k127_2920532_9 - - - - 0.000000000001088 70.0
HKD1_k127_2920561_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004602 287.0
HKD1_k127_2920561_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001072 229.0
HKD1_k127_2920561_2 - - - - 0.0000000000000000000000000000000000000685 159.0
HKD1_k127_2920561_3 oxidoreductase - - - 0.00000000000000000004487 103.0
HKD1_k127_2925742_0 B12 binding domain K00548 - 2.1.1.13 0.0 1307.0
HKD1_k127_2925742_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 596.0
HKD1_k127_2925742_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000002135 214.0
HKD1_k127_2925742_3 - - - - 0.0000000000000000000000000000000000000000000000000000001901 203.0
HKD1_k127_2925742_4 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000001234 163.0
HKD1_k127_2925742_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000001213 149.0
HKD1_k127_2925742_6 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000009481 152.0
HKD1_k127_2925742_7 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000546 102.0
HKD1_k127_2925742_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000001486 85.0
HKD1_k127_2925742_9 Iron permease FTR1 family K07243 - - 0.0000000000002886 75.0
HKD1_k127_2929840_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 589.0
HKD1_k127_2929840_1 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006384 269.0
HKD1_k127_2929840_2 sulfuric ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002006 287.0
HKD1_k127_2929840_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002211 249.0
HKD1_k127_2929840_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001469 235.0
HKD1_k127_2929840_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000004031 187.0
HKD1_k127_2929840_6 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000008745 138.0
HKD1_k127_2929840_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000002361 111.0
HKD1_k127_2929840_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000008409 101.0
HKD1_k127_2929840_9 - - - - 0.00000000000000001312 93.0
HKD1_k127_2931587_0 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000007087 228.0
HKD1_k127_2931587_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000001562 143.0
HKD1_k127_2931587_2 Rhomboid family - - - 0.000000000000000000000000004879 118.0
HKD1_k127_2931587_3 Winged helix DNA-binding domain - - - 0.000000000000000000001496 101.0
HKD1_k127_2931587_4 alcohol dehydrogenase K13979 - - 0.000000000000002902 75.0
HKD1_k127_2931587_5 - - - - 0.000000000007541 71.0
HKD1_k127_2931587_6 - - - - 0.000000003596 67.0
HKD1_k127_2932747_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 490.0
HKD1_k127_2932747_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 296.0
HKD1_k127_2932747_2 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004289 254.0
HKD1_k127_2932747_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.00000000000000004717 89.0
HKD1_k127_2941564_0 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 309.0
HKD1_k127_2941564_1 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008555 262.0
HKD1_k127_2941564_2 - - - - 0.00000000000000000005997 92.0
HKD1_k127_2942954_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 327.0
HKD1_k127_2942954_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 316.0
HKD1_k127_2942954_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 325.0
HKD1_k127_2942954_3 CAAX protease self-immunity K07052 - - 0.0000008022 59.0
HKD1_k127_2975291_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 5.164e-234 739.0
HKD1_k127_2975291_1 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 416.0
HKD1_k127_2975291_2 Belongs to the glycosyl hydrolase 18 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
HKD1_k127_2975291_3 NMT1-like family K07080 - - 0.000000000000000000000000000000000003058 142.0
HKD1_k127_2975291_4 - - - - 0.000000000000000009071 86.0
HKD1_k127_299051_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000007535 257.0
HKD1_k127_299051_1 ABC transporter related - - - 0.000000009192 57.0
HKD1_k127_299051_2 ABC transporter related - - - 0.0000001027 61.0
HKD1_k127_3014680_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000001861 169.0
HKD1_k127_3014680_1 Pyrophosphatase K06019 - 3.6.1.1 0.00000000000000000000000000000001771 134.0
HKD1_k127_3014680_2 Peptidase M56 K03646 - - 0.000000000000000000005068 105.0
HKD1_k127_3018522_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 399.0
HKD1_k127_3018522_1 GTP binding K06883 - - 0.000000000000000000000000000000000000001708 147.0
HKD1_k127_3018522_2 ABC-type dipeptide transport system periplasmic component - - - 0.000000000000000499 87.0
HKD1_k127_3019344_0 Domain of unknown function (DUF2088) - - - 1.794e-225 709.0
HKD1_k127_3019344_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005352 262.0
HKD1_k127_3019344_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000005968 123.0
HKD1_k127_303185_0 PAS fold-4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 504.0
HKD1_k127_3051793_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 353.0
HKD1_k127_3051793_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000001416 139.0
HKD1_k127_3051793_2 methyltransferase - - - 0.00006543 49.0
HKD1_k127_3057943_0 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000004224 197.0
HKD1_k127_3057943_1 PFAM membrane-flanked domain - - - 0.00000000000000000000000000000000000001542 152.0
HKD1_k127_3057943_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000003544 146.0
HKD1_k127_3057943_3 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000005582 107.0
HKD1_k127_3057943_4 FlgD Ig-like domain - - - 0.0000000000000000009376 98.0
HKD1_k127_3057943_5 Protein of unknown function (DUF507) K09804 - - 0.00000000000003938 76.0
HKD1_k127_3057943_6 Protein of unknown function (DUF507) K09804 - - 0.0000000000004474 72.0
HKD1_k127_3065913_0 glutamate carboxypeptidase K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 585.0
HKD1_k127_3065913_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000004393 198.0
HKD1_k127_3065913_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000001212 190.0
HKD1_k127_3065913_3 MerR, DNA binding - - - 0.000000000000000000000000000000000001591 143.0
HKD1_k127_3065913_4 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000004079 115.0
HKD1_k127_3076592_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 469.0
HKD1_k127_3076592_1 transferase activity, transferring glycosyl groups K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000521 235.0
HKD1_k127_3076592_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
HKD1_k127_3076592_3 PIN domain - - - 0.00000000000000000000000000000000000000003692 158.0
HKD1_k127_3076592_4 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000821 74.0
HKD1_k127_3081485_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 499.0
HKD1_k127_3081485_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 476.0
HKD1_k127_3081485_2 Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 338.0
HKD1_k127_3081485_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000002573 211.0
HKD1_k127_3081485_4 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000005028 200.0
HKD1_k127_3081485_5 - - - - 0.00000002615 63.0
HKD1_k127_3083626_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 372.0
HKD1_k127_3083626_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 361.0
HKD1_k127_3083626_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000176 291.0
HKD1_k127_3102896_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 484.0
HKD1_k127_3102896_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 449.0
HKD1_k127_3102896_2 PFAM Septum formation initiator K05589 - - 0.00004129 50.0
HKD1_k127_3132858_0 Phosphotransferase enzyme family - - - 4.076e-307 974.0
HKD1_k127_3132858_1 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity K01954,K01955,K03660,K11540,K11541,K19656 GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141 2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 422.0
HKD1_k127_3132858_2 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
HKD1_k127_3132858_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 282.0
HKD1_k127_3153541_0 Peptidase dimerisation domain K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 548.0
HKD1_k127_3153541_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
HKD1_k127_3153541_2 Domain of unknown function (DUF4340) - - - 0.0000000000000002483 91.0
HKD1_k127_3176287_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 577.0
HKD1_k127_3176287_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000009089 250.0
HKD1_k127_3176287_2 Belongs to the LOG family - - - 0.000000000000000000008682 101.0
HKD1_k127_3176287_3 metallophosphoesterase K07096 - - 0.000000000000008807 78.0
HKD1_k127_3183_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002199 308.0
HKD1_k127_3183_1 Rhomboid family - - - 0.000000000000000000000000000000006413 139.0
HKD1_k127_3183069_0 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 494.0
HKD1_k127_3183069_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 422.0
HKD1_k127_3183069_10 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000004056 100.0
HKD1_k127_3183069_11 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000003866 88.0
HKD1_k127_3183069_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007275 282.0
HKD1_k127_3183069_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000009348 273.0
HKD1_k127_3183069_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000001961 238.0
HKD1_k127_3183069_5 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000202 209.0
HKD1_k127_3183069_6 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000003616 190.0
HKD1_k127_3183069_7 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000007309 145.0
HKD1_k127_3183069_8 maltose O-acetyltransferase activity - - - 0.00000000000000000000000006828 114.0
HKD1_k127_3183069_9 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000001213 99.0
HKD1_k127_3190363_0 Belongs to the aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 454.0
HKD1_k127_3190363_1 - - - - 0.0006884 52.0
HKD1_k127_3200016_0 Response regulator, receiver K01007 - 2.7.9.2 0.0 1296.0
HKD1_k127_3200016_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 3.594e-245 762.0
HKD1_k127_3200016_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000825 220.0
HKD1_k127_3200016_3 ethanolamine catabolic process - - - 0.00000000000000000000000000000000332 130.0
HKD1_k127_3200016_4 - - - - 0.00000000000000000000379 96.0
HKD1_k127_3202403_0 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007207 278.0
HKD1_k127_3202403_1 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000005741 190.0
HKD1_k127_3202403_2 - - - - 0.000000000000000000000000000000000000000000000000003204 187.0
HKD1_k127_3202403_3 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001032 130.0
HKD1_k127_3203991_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 1.231e-209 667.0
HKD1_k127_3203991_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 466.0
HKD1_k127_3203991_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 370.0
HKD1_k127_3203991_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000104 134.0
HKD1_k127_3225606_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1307.0
HKD1_k127_3231573_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 516.0
HKD1_k127_3231573_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 413.0
HKD1_k127_3231573_2 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001163 276.0
HKD1_k127_3231573_3 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000367 154.0
HKD1_k127_3231573_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000058 140.0
HKD1_k127_3231985_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 467.0
HKD1_k127_3231985_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 324.0
HKD1_k127_3231985_2 Tetratricopeptide repeat - - - 0.00000000000000001902 87.0
HKD1_k127_3232164_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 530.0
HKD1_k127_3232164_1 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
HKD1_k127_3232164_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000002018 138.0
HKD1_k127_3232164_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000001824 116.0
HKD1_k127_3279405_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00316 - 1.5.99.6 2.524e-200 642.0
HKD1_k127_3279405_1 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 586.0
HKD1_k127_3279405_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 465.0
HKD1_k127_3279405_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007541 261.0
HKD1_k127_3279405_4 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000001877 94.0
HKD1_k127_3279405_5 Flavin containing amine oxidoreductase - - - 0.0009344 46.0
HKD1_k127_3317957_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001059 282.0
HKD1_k127_3317957_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009928 264.0
HKD1_k127_3317957_2 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000001593 151.0
HKD1_k127_3333059_0 'Xanthine and CO dehydrogenases maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 395.0
HKD1_k127_3333059_1 SPTR ATPase associated with various cellular activities AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 381.0
HKD1_k127_3333059_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 330.0
HKD1_k127_3333059_3 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 289.0
HKD1_k127_3333059_4 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000004381 153.0
HKD1_k127_3333059_5 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000001925 132.0
HKD1_k127_3335412_0 Putative methyltransferase K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003658 277.0
HKD1_k127_3335412_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008653 239.0
HKD1_k127_3335412_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000007027 128.0
HKD1_k127_3335412_3 Regulatory protein, FmdB - - - 0.000000000000000000008517 95.0
HKD1_k127_3340213_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 303.0
HKD1_k127_3340213_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000001916 173.0
HKD1_k127_3351894_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000002787 170.0
HKD1_k127_3351894_1 HEAT repeats K03301 - - 0.0000000000000000008816 102.0
HKD1_k127_3351894_2 Major Facilitator Superfamily K03301 - - 0.000000007641 63.0
HKD1_k127_337583_0 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000008059 139.0
HKD1_k127_337583_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000003507 126.0
HKD1_k127_3381488_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 450.0
HKD1_k127_3381488_1 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 282.0
HKD1_k127_3381488_2 CHAT domain - - - 0.000134 44.0
HKD1_k127_3387379_0 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 306.0
HKD1_k127_3387379_2 transcriptional regulator - - - 0.0000000000000000000000000000001709 130.0
HKD1_k127_3387379_3 GYD domain - - - 0.000000000000000000000000000001571 123.0
HKD1_k127_3387379_4 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000003129 134.0
HKD1_k127_3387379_5 von Willebrand factor, type A - - - 0.000000000000000000001445 106.0
HKD1_k127_3416943_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.787e-206 659.0
HKD1_k127_3416943_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 513.0
HKD1_k127_3416943_10 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002037 219.0
HKD1_k127_3416943_11 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000006497 168.0
HKD1_k127_3416943_12 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000008409 123.0
HKD1_k127_3416943_13 phosphorelay signal transduction system K02437 - - 0.000000000000000000000000002492 120.0
HKD1_k127_3416943_14 Domain of unknown function (DUF4157) - - - 0.00000000000000000001111 108.0
HKD1_k127_3416943_15 Cytochrome c7 and related cytochrome c - - - 0.000000001377 71.0
HKD1_k127_3416943_16 Serine threonine protein kinase - - - 0.0000004836 61.0
HKD1_k127_3416943_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 445.0
HKD1_k127_3416943_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 422.0
HKD1_k127_3416943_4 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 432.0
HKD1_k127_3416943_5 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 390.0
HKD1_k127_3416943_6 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
HKD1_k127_3416943_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 312.0
HKD1_k127_3416943_8 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 306.0
HKD1_k127_3416943_9 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
HKD1_k127_3430068_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1195.0
HKD1_k127_3430068_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 301.0
HKD1_k127_3436370_0 Type III secretion protein K03230 - - 9.864e-220 702.0
HKD1_k127_3436370_1 FlhB HrpN YscU SpaS Family K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000009423 237.0
HKD1_k127_3436370_2 Type III secretion K03228 - - 0.0000000000001259 77.0
HKD1_k127_3439989_0 transmembrane transporter activity K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 559.0
HKD1_k127_3439989_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005777 290.0
HKD1_k127_3439989_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000038 84.0
HKD1_k127_3439989_3 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.000008122 57.0
HKD1_k127_3439989_4 - - - - 0.0001412 49.0
HKD1_k127_3446512_0 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 449.0
HKD1_k127_3446512_1 glutamate-cysteine ligase activity K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 420.0
HKD1_k127_3446512_2 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
HKD1_k127_3446512_3 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000006372 69.0
HKD1_k127_3452489_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 378.0
HKD1_k127_3452489_1 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 354.0
HKD1_k127_3452489_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001789 265.0
HKD1_k127_3452489_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000001389 204.0
HKD1_k127_3452489_4 Outer membrane lipoprotein K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000003051 137.0
HKD1_k127_3452489_5 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000007592 128.0
HKD1_k127_3452489_6 PASTA domain K12132 - 2.7.11.1 0.0000000000000000000001336 106.0
HKD1_k127_3458709_0 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003331 264.0
HKD1_k127_3458709_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000001109 187.0
HKD1_k127_3458709_2 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000131 117.0
HKD1_k127_3458709_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000001662 78.0
HKD1_k127_3460743_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 593.0
HKD1_k127_3460743_1 Stage II sporulation protein - - - 0.0000000000000000000000000000006673 124.0
HKD1_k127_3460743_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000002563 124.0
HKD1_k127_3467060_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
HKD1_k127_3467060_1 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000001665 144.0
HKD1_k127_3467646_0 PQQ enzyme repeat - - - 0.0000000000000000000000002463 115.0
HKD1_k127_3468613_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004555 278.0
HKD1_k127_3468613_1 PFAM Ubiquitin-conjugating - - - 0.0000000000000000000000000001673 121.0
HKD1_k127_3468613_2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.0000000000000000000003886 106.0
HKD1_k127_3468613_3 WXG100 protein secretion system (Wss), protein YukD - - - 0.000000000002794 70.0
HKD1_k127_3468613_4 PFAM Appr-1-p processing domain protein - - - 0.00000000001245 66.0
HKD1_k127_3468613_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000003203 51.0
HKD1_k127_3483417_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 542.0
HKD1_k127_3483417_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000001202 190.0
HKD1_k127_3483417_2 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000001173 156.0
HKD1_k127_3484710_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 481.0
HKD1_k127_3484710_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 372.0
HKD1_k127_3484710_2 - - - - 0.000000000000000000000000000000000001636 153.0
HKD1_k127_3485975_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HKD1_k127_3485975_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 293.0
HKD1_k127_3485975_2 TIGRFAM Phosphohistidine phosphatase SixA K08296 - - 0.000000000000003327 83.0
HKD1_k127_349030_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 331.0
HKD1_k127_349030_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000001976 169.0
HKD1_k127_349030_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000007789 140.0
HKD1_k127_3496883_0 4Fe-4S dicluster domain K00184 - - 0.0 1146.0
HKD1_k127_3496883_1 Polysulphide reductase, NrfD K00185 - - 1.303e-221 696.0
HKD1_k127_3496883_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004429 246.0
HKD1_k127_3496883_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004439 248.0
HKD1_k127_3496883_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000004966 179.0
HKD1_k127_3496883_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000001093 89.0
HKD1_k127_3503369_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 370.0
HKD1_k127_3503369_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 306.0
HKD1_k127_3503369_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001189 280.0
HKD1_k127_3503369_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000103 166.0
HKD1_k127_3503369_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000001472 178.0
HKD1_k127_3503369_5 PFAM GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000001002 87.0
HKD1_k127_3509352_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
HKD1_k127_3509352_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000004898 147.0
HKD1_k127_3509352_2 - - - - 0.0000000000000000000000000004825 115.0
HKD1_k127_3509352_3 - - - - 0.0000000000000000000002454 100.0
HKD1_k127_3509352_4 amidohydrolase - - - 0.000004693 58.0
HKD1_k127_3518903_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000004577 234.0
HKD1_k127_3518903_1 - - - - 0.00000000000000000000000000000000000000000000000000000000004563 219.0
HKD1_k127_3518903_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001053 191.0
HKD1_k127_3518903_3 peptidase - - - 0.000000000000000000000000000001512 128.0
HKD1_k127_3518903_4 cell redox homeostasis - - - 0.000000000000000000000000000008706 130.0
HKD1_k127_3520447_0 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 323.0
HKD1_k127_3520447_1 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000002291 226.0
HKD1_k127_3520447_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000002232 183.0
HKD1_k127_3520447_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000001864 125.0
HKD1_k127_3520447_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000006076 116.0
HKD1_k127_3530054_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.128e-224 725.0
HKD1_k127_3530054_1 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 512.0
HKD1_k127_3530054_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002701 183.0
HKD1_k127_3530054_3 - - - - 0.00000000000000000000000000000000000000001031 160.0
HKD1_k127_3530054_4 CBS domain K03699 - - 0.00000000000000000000000000692 114.0
HKD1_k127_3530054_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00001088 51.0
HKD1_k127_3535050_0 AcrB/AcrD/AcrF family - - - 0.0 1242.0
HKD1_k127_3535050_1 Belongs to the arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 306.0
HKD1_k127_3535050_2 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004152 269.0
HKD1_k127_3535050_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009888 236.0
HKD1_k127_3535050_4 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000006531 236.0
HKD1_k127_3535050_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000135 188.0
HKD1_k127_3535050_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000003112 164.0
HKD1_k127_3535050_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000002924 115.0
HKD1_k127_3535050_8 nucleotide catabolic process - - - 0.0000000000000000000001668 106.0
HKD1_k127_3535050_9 Protein of unknown function (DUF2892) - - - 0.0000000000000005143 84.0
HKD1_k127_3545193_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000008876 130.0
HKD1_k127_3551216_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 7.53e-208 675.0
HKD1_k127_3551216_1 Tetratricopeptide repeat - - - 0.000000000000000000007303 98.0
HKD1_k127_3551216_2 Autotransporter beta-domain - - - 0.0000000009415 69.0
HKD1_k127_3551216_3 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000005481 64.0
HKD1_k127_3564163_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.37e-247 772.0
HKD1_k127_3564163_1 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 402.0
HKD1_k127_3564163_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000002165 167.0
HKD1_k127_3564163_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000001096 145.0
HKD1_k127_3564163_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000003468 141.0
HKD1_k127_3564163_5 Putative zinc-finger - - - 0.0000002827 57.0
HKD1_k127_3575972_0 transmembrane transporter activity K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 353.0
HKD1_k127_3575972_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000174 256.0
HKD1_k127_3575972_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000005938 145.0
HKD1_k127_3575972_3 outer membrane efflux protein K15725 - - 0.000000000000000000000000001329 126.0
HKD1_k127_3575972_4 PIN domain K07062 - - 0.000000000837 64.0
HKD1_k127_3585765_0 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 508.0
HKD1_k127_3585765_1 Domain of unknown function (DUF5122) beta-propeller K14274,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 502.0
HKD1_k127_3585765_10 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000369 141.0
HKD1_k127_3585765_11 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000264 157.0
HKD1_k127_3585765_12 polysaccharide biosynthetic process K00655,K00721 - 2.3.1.51,2.4.1.83 0.000000000000000000000000003003 129.0
HKD1_k127_3585765_13 Uncharacterized small protein (DUF2292) - - - 0.00000002248 56.0
HKD1_k127_3585765_14 GDSL-like Lipase/Acylhydrolase family K06882 - - 0.0001227 55.0
HKD1_k127_3585765_2 ATPase activity K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 453.0
HKD1_k127_3585765_3 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 372.0
HKD1_k127_3585765_4 sulfate ABC transporter K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 356.0
HKD1_k127_3585765_5 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 333.0
HKD1_k127_3585765_6 Male sterility protein K15891 - 1.1.1.354 0.000000000000000000000000000000000000000000000000000000000000002055 232.0
HKD1_k127_3585765_7 activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000005364 167.0
HKD1_k127_3585765_8 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000001333 164.0
HKD1_k127_3585765_9 TRANSCRIPTIONal - - - 0.0000000000000000000000000000000000000178 146.0
HKD1_k127_3590752_0 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
HKD1_k127_3590752_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000009275 248.0
HKD1_k127_3590752_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000001249 226.0
HKD1_k127_3590752_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000008923 105.0
HKD1_k127_3590752_4 phosphorelay signal transduction system - - - 0.000000000000004956 85.0
HKD1_k127_3601366_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 3.324e-235 750.0
HKD1_k127_3601366_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 514.0
HKD1_k127_3601366_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 367.0
HKD1_k127_3601366_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 291.0
HKD1_k127_3601366_4 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001171 288.0
HKD1_k127_3601366_5 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
HKD1_k127_3601366_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002125 192.0
HKD1_k127_3602512_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 493.0
HKD1_k127_3602512_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 380.0
HKD1_k127_3602512_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000003375 122.0
HKD1_k127_3602564_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 417.0
HKD1_k127_3602564_1 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000287 81.0
HKD1_k127_3602564_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000004833 64.0
HKD1_k127_3604322_0 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 422.0
HKD1_k127_3604322_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000001183 161.0
HKD1_k127_3604322_3 nitric oxide dioxygenase activity K13735 - - 0.0000000003126 70.0
HKD1_k127_3617887_0 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 342.0
HKD1_k127_3617887_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 288.0
HKD1_k127_3617887_2 - - - - 0.0000000000000000000002511 99.0
HKD1_k127_3617887_3 - - - - 0.000000000000000000004756 107.0
HKD1_k127_3617887_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000001783 70.0
HKD1_k127_3630716_0 PFAM Iron permease FTR1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 343.0
HKD1_k127_3630716_1 transporter (permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001469 277.0
HKD1_k127_3630716_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001728 274.0
HKD1_k127_3630716_3 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000008624 121.0
HKD1_k127_3630716_4 Efflux ABC transporter, permease protein K02004 - - 0.000000000000000000000000000122 128.0
HKD1_k127_3647881_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 552.0
HKD1_k127_3666884_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 316.0
HKD1_k127_3666884_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000003005 225.0
HKD1_k127_3666884_2 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000001581 156.0
HKD1_k127_3666884_3 COG0457 FOG TPR repeat - - - 0.0008648 52.0
HKD1_k127_3682132_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 591.0
HKD1_k127_3682132_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000009846 166.0
HKD1_k127_3682132_2 - - - - 0.00000000000000000000004471 105.0
HKD1_k127_3685358_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
HKD1_k127_3685358_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
HKD1_k127_3685358_10 Glutamine amidotransferase class-I - - - 0.0000005365 61.0
HKD1_k127_3685358_11 - - - - 0.000004162 58.0
HKD1_k127_3685358_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006214 251.0
HKD1_k127_3685358_3 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000003331 215.0
HKD1_k127_3685358_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000006447 169.0
HKD1_k127_3685358_5 Tetratricopeptide repeat - - - 0.0000000000000000002102 102.0
HKD1_k127_3685358_6 fatty acid desaturase - - - 0.0000000000000000006313 98.0
HKD1_k127_3685358_7 SMART cyclic nucleotide-binding - - - 0.0000000000000000114 94.0
HKD1_k127_3685358_8 heat shock protein binding - - - 0.0000000000000003667 91.0
HKD1_k127_3685358_9 Cysteine-rich secretory protein family - - - 0.000000000000002141 86.0
HKD1_k127_369592_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 554.0
HKD1_k127_369592_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 552.0
HKD1_k127_369592_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 398.0
HKD1_k127_369592_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 305.0
HKD1_k127_369592_4 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000003374 64.0
HKD1_k127_3699908_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 279.0
HKD1_k127_3699908_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004283 302.0
HKD1_k127_3699908_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000003011 216.0
HKD1_k127_370939_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 305.0
HKD1_k127_370939_2 Malate synthase K01638 - 2.3.3.9 0.0000000000000000000000000008909 120.0
HKD1_k127_370939_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00006729 48.0
HKD1_k127_3718464_0 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 349.0
HKD1_k127_3718748_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1259.0
HKD1_k127_3718748_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 319.0
HKD1_k127_3718748_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
HKD1_k127_3718748_3 YHS domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000001506 233.0
HKD1_k127_3718748_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000001641 62.0
HKD1_k127_3726244_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 2.502e-197 625.0
HKD1_k127_3726244_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 329.0
HKD1_k127_3726244_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K05970 - 3.1.1.53 0.00000000008338 78.0
HKD1_k127_3726244_11 Endonuclease/Exonuclease/phosphatase family - - - 0.000003701 62.0
HKD1_k127_3726244_12 Tetratricopeptide repeat - - - 0.00003438 54.0
HKD1_k127_3726244_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000001641 252.0
HKD1_k127_3726244_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000003553 214.0
HKD1_k127_3726244_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000003451 169.0
HKD1_k127_3726244_5 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.000000000000000000000000000000000000000004111 163.0
HKD1_k127_3726244_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000009827 148.0
HKD1_k127_3726244_7 Domain of unknown function (DUF4388) - - - 0.000000000000000003258 98.0
HKD1_k127_3726244_8 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K00528 - 1.18.1.2,1.19.1.1 0.000000000000001366 88.0
HKD1_k127_3726244_9 DGQHR domain - - - 0.0000000000007389 78.0
HKD1_k127_3727180_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 593.0
HKD1_k127_3727180_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000001723 152.0
HKD1_k127_3727180_2 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000002775 149.0
HKD1_k127_3727180_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00002085 55.0
HKD1_k127_3735792_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000008389 229.0
HKD1_k127_3735792_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000002009 134.0
HKD1_k127_3735792_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000001871 68.0
HKD1_k127_3735792_3 Transglutaminase-like superfamily - - - 0.000000001371 71.0
HKD1_k127_3735792_4 PilZ domain - - - 0.00003781 51.0
HKD1_k127_3756971_0 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 281.0
HKD1_k127_3756971_1 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000001218 234.0
HKD1_k127_3756971_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000007329 169.0
HKD1_k127_3756971_3 COG1520 FOG WD40-like repeat - - - 0.00002189 53.0
HKD1_k127_3760259_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 480.0
HKD1_k127_3760259_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001398 249.0
HKD1_k127_3760259_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000001814 149.0
HKD1_k127_3764822_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1053.0
HKD1_k127_3764822_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 425.0
HKD1_k127_3764822_2 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HKD1_k127_3764822_3 COG0666 FOG Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000000000000003642 203.0
HKD1_k127_3764822_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000003289 160.0
HKD1_k127_3764822_5 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000000000000000000000000000000006952 139.0
HKD1_k127_3764822_6 YtxH-like protein - - - 0.0000000000003074 74.0
HKD1_k127_3779295_0 Tetratricopeptide repeat - - - 0.00000000000000001095 96.0
HKD1_k127_3779295_1 PKD domain containing protein - - - 0.000000000000005088 79.0
HKD1_k127_3779295_2 Roadblock/LC7 domain - - - 0.000000002905 64.0
HKD1_k127_3791534_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 483.0
HKD1_k127_3791534_1 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 317.0
HKD1_k127_3791534_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000306 104.0
HKD1_k127_3807878_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 619.0
HKD1_k127_3807878_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003359 295.0
HKD1_k127_3807878_2 - - - - 0.0000000000000001945 82.0
HKD1_k127_3807878_3 UbiA prenyltransferase family - - - 0.00000000003579 66.0
HKD1_k127_3807878_4 von Willebrand factor (vWF) type A domain - - - 0.000003769 57.0
HKD1_k127_3811996_0 RDD family - - - 0.00000000000000000000000000000000000000000000000000004678 198.0
HKD1_k127_3811996_1 - - - - 0.00000000000000000000000000000000000000000002053 168.0
HKD1_k127_3811996_2 - - - - 0.0000000000001386 80.0
HKD1_k127_3811996_3 Belongs to the BshC family K22136 - - 0.0000000004533 64.0
HKD1_k127_3830395_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000001458 165.0
HKD1_k127_3830395_1 polysaccharide catabolic process - - - 0.0000000000000000000000003362 117.0
HKD1_k127_3830395_2 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000189 109.0
HKD1_k127_3846056_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 332.0
HKD1_k127_3846056_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000004718 195.0
HKD1_k127_3846056_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000001745 140.0
HKD1_k127_3846056_3 HEAT repeats - - - 0.00000000000000000000000000005077 128.0
HKD1_k127_3846056_4 - - - - 0.00000000000000000000000004986 118.0
HKD1_k127_3846535_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.06e-247 774.0
HKD1_k127_3846535_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000249 95.0
HKD1_k127_3864160_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000001172 126.0
HKD1_k127_3864160_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000009513 81.0
HKD1_k127_3871455_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1133.0
HKD1_k127_3871455_1 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 335.0
HKD1_k127_3899212_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 4.077e-214 691.0
HKD1_k127_3899212_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000001446 183.0
HKD1_k127_3899212_2 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000001214 156.0
HKD1_k127_3899212_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000004268 167.0
HKD1_k127_3899212_4 - - - - 0.000000000000000000000002387 105.0
HKD1_k127_3899212_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000007597 86.0
HKD1_k127_3899212_7 Periplasmic or secreted lipoprotein - - - 0.00000000009533 63.0
HKD1_k127_3899212_9 snoRNA binding - - - 0.00002164 49.0
HKD1_k127_3923838_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 433.0
HKD1_k127_3923838_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 361.0
HKD1_k127_3923838_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 315.0
HKD1_k127_3923838_3 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000003395 225.0
HKD1_k127_3923838_4 Haemolysin-type calcium-binding - - - 0.000000000000000000000000000000000000000000000000000000000001975 232.0
HKD1_k127_3923838_5 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000001152 145.0
HKD1_k127_3923838_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000001637 115.0
HKD1_k127_3923838_7 Hep Hag repeat protein - - - 0.0000000002756 68.0
HKD1_k127_3924022_0 enterotoxin - - - 2.43e-207 672.0
HKD1_k127_3924022_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000002705 207.0
HKD1_k127_3924022_2 - - - - 0.0000000000000000000000000000000000000000000002947 171.0
HKD1_k127_3924022_3 PKD domain containing protein K19355 - 3.2.1.78 0.000000000689 70.0
HKD1_k127_3947260_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 4.918e-296 916.0
HKD1_k127_3947260_1 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
HKD1_k127_3947260_2 Alkylmercury lyase - - - 0.000000000000000000002222 99.0
HKD1_k127_3947260_3 Alkylmercury lyase - - - 0.00007796 47.0
HKD1_k127_3982119_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
HKD1_k127_3982119_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 407.0
HKD1_k127_3982119_2 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 381.0
HKD1_k127_3982119_3 glycolate biosynthetic process K01091,K05967,K07025 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 301.0
HKD1_k127_3982119_4 domain, Protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 329.0
HKD1_k127_3982119_5 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000691 236.0
HKD1_k127_3982119_6 DinB family - - - 0.0000000000000000000000000000000002816 139.0
HKD1_k127_3982119_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001146 109.0
HKD1_k127_3982119_8 CHAD domain - - - 0.00000000002983 72.0
HKD1_k127_3986085_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 3.753e-220 695.0
HKD1_k127_3986085_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 602.0
HKD1_k127_3986085_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 419.0
HKD1_k127_3986085_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000694 117.0
HKD1_k127_3986085_4 - - - - 0.0000000000000003341 85.0
HKD1_k127_3986085_5 deoxyhypusine monooxygenase activity - - - 0.0000000002083 71.0
HKD1_k127_4009897_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 6.708e-212 668.0
HKD1_k127_4009897_1 Hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000004594 259.0
HKD1_k127_4009897_2 Belongs to the UPF0761 family K07058 - - 0.000000000000000000000000000007635 129.0
HKD1_k127_4010164_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 441.0
HKD1_k127_4010164_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 327.0
HKD1_k127_4010164_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000001391 173.0
HKD1_k127_4010385_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005094 241.0
HKD1_k127_4010385_1 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000002648 72.0
HKD1_k127_4036350_0 Prokaryotic cytochrome b561 - - - 1.333e-250 792.0
HKD1_k127_4036350_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 538.0
HKD1_k127_4036350_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 354.0
HKD1_k127_4036350_3 Abc transporter K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
HKD1_k127_4036350_4 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005184 259.0
HKD1_k127_4036350_5 Gamma-glutamyl-gamma-aminobutyrate hydrolase K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000001282 235.0
HKD1_k127_4036350_6 3-demethylubiquinone-9 3-O-methyltransferase activity K15257,K16868,K18827,K20444 - 2.1.1.265,2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000001394 210.0
HKD1_k127_4036350_7 Dodecin K09165 - - 0.000000000000000001521 89.0
HKD1_k127_4036350_8 PQQ-like domain - - - 0.0001325 51.0
HKD1_k127_403749_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004697 252.0
HKD1_k127_4039735_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001906 274.0
HKD1_k127_4082942_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.476e-297 918.0
HKD1_k127_4082942_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 526.0
HKD1_k127_4082942_2 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 423.0
HKD1_k127_4082942_3 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000008953 226.0
HKD1_k127_4082942_4 - - - - 0.00000000000000000000000000000000000000000469 162.0
HKD1_k127_4082942_5 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.0000000000000000000003344 102.0
HKD1_k127_4082942_6 GyrI-like small molecule binding domain - - - 0.0000000001063 68.0
HKD1_k127_4082942_7 Amb_all K01728 - 4.2.2.2 0.000005033 59.0
HKD1_k127_4094210_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 477.0
HKD1_k127_4094210_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 470.0
HKD1_k127_409878_0 DNA topoisomerase II activity K03167 - 5.99.1.3 1.542e-265 829.0
HKD1_k127_409878_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 485.0
HKD1_k127_4104712_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000005013 221.0
HKD1_k127_4104712_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000155 222.0
HKD1_k127_4104712_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000002094 169.0
HKD1_k127_4104712_3 antisigma factor binding K04749,K06378 - - 0.000000000000000000000000003218 114.0
HKD1_k127_4104712_4 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000002174 104.0
HKD1_k127_4104712_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000566 96.0
HKD1_k127_4104712_6 - - - - 0.00000000000002 76.0
HKD1_k127_4104712_7 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000008347 78.0
HKD1_k127_4104712_8 Putative peptidoglycan binding domain - - - 0.0000007898 56.0
HKD1_k127_4112134_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 558.0
HKD1_k127_4112134_1 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
HKD1_k127_4112134_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000002767 228.0
HKD1_k127_4112134_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000001725 220.0
HKD1_k127_4123880_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000001177 196.0
HKD1_k127_4123880_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000001158 190.0
HKD1_k127_4123880_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000001191 182.0
HKD1_k127_4123880_3 - - - - 0.00000000000000000000000007909 110.0
HKD1_k127_4123880_4 PFAM membrane protein of K08972 - - 0.000000000068 68.0
HKD1_k127_4136822_0 sigma factor activity K02405 - - 0.0000000000000000000000002499 113.0
HKD1_k127_4136822_1 Forkhead associated domain - - - 0.00000000188 70.0
HKD1_k127_4136822_2 Flagellar biosynthesis protein, FliO - - - 0.00000009213 59.0
HKD1_k127_4138055_0 Putative collagen-binding domain of a collagenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 342.0
HKD1_k127_4138055_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001526 233.0
HKD1_k127_4138055_2 cellulase activity - - - 0.00000004653 64.0
HKD1_k127_4139474_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000007434 243.0
HKD1_k127_4139474_1 - - - - 0.00000000000000000000000000000000000000000000000000000001448 212.0
HKD1_k127_4139474_2 cheY-homologous receiver domain K03413 - - 0.00000000000000002028 88.0
HKD1_k127_4140916_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
HKD1_k127_4140916_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001137 246.0
HKD1_k127_4140916_2 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000002373 179.0
HKD1_k127_4140916_3 transcriptional regulator - - - 0.0000000000000000000000027 109.0
HKD1_k127_4140916_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00003445 58.0
HKD1_k127_4146537_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 445.0
HKD1_k127_4146537_1 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 344.0
HKD1_k127_4146537_2 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002029 266.0
HKD1_k127_4146537_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000003268 63.0
HKD1_k127_4153033_0 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004789 257.0
HKD1_k127_4153033_1 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 245.0
HKD1_k127_4153033_2 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000001281 178.0
HKD1_k127_4153033_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000198 180.0
HKD1_k127_4153033_4 STAS domain K17762 - - 0.0000000000000000000000000000000000000000000000376 172.0
HKD1_k127_4153033_5 Sigma-54 interaction domain K07714,K07715 - - 0.0000000000000003216 82.0
HKD1_k127_415383_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 340.0
HKD1_k127_415383_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 339.0
HKD1_k127_415383_2 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 309.0
HKD1_k127_415632_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000002527 214.0
HKD1_k127_415632_1 sequence-specific DNA binding K03719,K05800 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000005649 165.0
HKD1_k127_415632_2 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000374 143.0
HKD1_k127_415632_3 PilZ domain - - - 0.00000000000000000000000000000004491 134.0
HKD1_k127_415632_4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000005207 63.0
HKD1_k127_415632_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000001061 64.0
HKD1_k127_4169625_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1170.0
HKD1_k127_4169625_1 GTP-binding protein TypA K06207 - - 1.199e-256 805.0
HKD1_k127_4169625_2 Sigma-54 interaction domain K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 342.0
HKD1_k127_4169625_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000242 265.0
HKD1_k127_4169625_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
HKD1_k127_4169625_5 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000002129 90.0
HKD1_k127_4169625_6 von Willebrand factor, type A - - - 0.00000000000000002153 93.0
HKD1_k127_4178380_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 437.0
HKD1_k127_4178380_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 402.0
HKD1_k127_4178380_2 Tetratricopeptide repeat K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005422 280.0
HKD1_k127_4178380_3 DNA polymerase K02350 - 2.7.7.7 0.00001125 51.0
HKD1_k127_4186800_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 544.0
HKD1_k127_4186800_1 Belongs to the arginase family K01476 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HKD1_k127_4186800_2 GTP binding K06883 - - 0.00000000000000000000000003688 117.0
HKD1_k127_4189227_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 343.0
HKD1_k127_4189227_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 330.0
HKD1_k127_4193573_0 SPTR Glycosyl hydrolase, BNR repeat-containing protein - - - 1.4e-311 985.0
HKD1_k127_4193573_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 3.818e-233 729.0
HKD1_k127_4193573_2 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 367.0
HKD1_k127_4193573_3 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 345.0
HKD1_k127_4193573_4 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
HKD1_k127_4193573_5 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000005444 236.0
HKD1_k127_4193573_6 DinB superfamily - - - 0.0000000000000000000000000007499 118.0
HKD1_k127_4193573_7 - - - - 0.0000000000000004454 83.0
HKD1_k127_4193573_8 - - - - 0.00008974 52.0
HKD1_k127_4200619_0 amino acid - - - 5.177e-210 673.0
HKD1_k127_4200619_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 581.0
HKD1_k127_4200619_10 - - - - 0.00000000000000000000000006664 116.0
HKD1_k127_4200619_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 564.0
HKD1_k127_4200619_3 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
HKD1_k127_4200619_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 287.0
HKD1_k127_4200619_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003451 282.0
HKD1_k127_4200619_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
HKD1_k127_4200619_7 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003135 247.0
HKD1_k127_4200619_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000002875 204.0
HKD1_k127_4200619_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000002801 113.0
HKD1_k127_4205331_0 Asparaginase, N-terminal K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001216 233.0
HKD1_k127_4205331_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000004386 117.0
HKD1_k127_4205331_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000006352 97.0
HKD1_k127_4212506_0 Rhs Family K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002628 295.0
HKD1_k127_4212506_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000009413 195.0
HKD1_k127_4212506_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000003497 198.0
HKD1_k127_4212506_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000002383 138.0
HKD1_k127_4252053_0 hyperosmotic response - - - 0.000000000000000000000002693 113.0
HKD1_k127_4252053_2 the current gene model (or a revised gene model) may contain a premature stop - - - 0.000006764 51.0
HKD1_k127_4252053_3 - - - - 0.000439 51.0
HKD1_k127_4252053_4 SMART Tetratricopeptide repeat - - - 0.0006895 47.0
HKD1_k127_4265731_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
HKD1_k127_4265731_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000009809 194.0
HKD1_k127_4265731_2 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000003535 191.0
HKD1_k127_4265731_3 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.00000000000000000001012 108.0
HKD1_k127_4298506_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 312.0
HKD1_k127_4298506_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000001802 242.0
HKD1_k127_4298506_2 transcriptional K02081 - - 0.000000000204 63.0
HKD1_k127_4300822_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 317.0
HKD1_k127_4300822_1 COGs COG0433 ATPase K06915 - - 0.000000000000000000000000000000000000000000000000000000000000002532 228.0
HKD1_k127_4300822_2 COGs COG2380 conserved K09785 - - 0.0000000000000000000000000000000483 141.0
HKD1_k127_4300822_3 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.000000000000000000000000000001546 121.0
HKD1_k127_4300822_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05787 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 - 0.00000000000000000000000001443 112.0
HKD1_k127_4307253_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
HKD1_k127_4307253_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004903 249.0
HKD1_k127_4307253_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000002455 196.0
HKD1_k127_4307253_3 - - - - 0.00000000000000000000000000000014 135.0
HKD1_k127_4307253_4 alpha-ribazole phosphatase activity K01834 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.11 0.0000000000000000000001621 104.0
HKD1_k127_4307253_5 two component, sigma54 specific, transcriptional regulator, Fis family K07715 GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000005903 91.0
HKD1_k127_4307253_6 Universal stress protein K06149 - - 0.00000000000000005002 91.0
HKD1_k127_4317599_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 353.0
HKD1_k127_4317599_1 COGs COG0433 ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005289 276.0
HKD1_k127_434400_0 Bacterial protein of unknown function (DUF885) - - - 2.904e-207 659.0
HKD1_k127_434400_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 454.0
HKD1_k127_434400_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
HKD1_k127_434400_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000005483 181.0
HKD1_k127_434400_4 Major Facilitator Superfamily K03535 - - 0.000001866 52.0
HKD1_k127_434400_5 Prokaryotic RING finger family 1 - - - 0.000002294 56.0
HKD1_k127_4347837_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 5.652e-195 618.0
HKD1_k127_4347837_1 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000001014 172.0
HKD1_k127_4347837_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000002798 148.0
HKD1_k127_4347837_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000005309 83.0
HKD1_k127_4347837_4 50S ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000004248 67.0
HKD1_k127_4354747_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 452.0
HKD1_k127_4354747_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
HKD1_k127_4354747_2 PFAM glycoside hydrolase, family 18 - - - 0.00000000000000000000000000000000000000000000000000000000001531 218.0
HKD1_k127_4354747_3 phosphorelay signal transduction system K02490,K10126 - - 0.000000000000000000005786 99.0
HKD1_k127_4354747_4 - - - - 0.0000007485 55.0
HKD1_k127_4359465_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 299.0
HKD1_k127_4359465_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000003903 222.0
HKD1_k127_4359465_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000005135 164.0
HKD1_k127_4359465_3 - - - - 0.0000000000000000003194 89.0
HKD1_k127_4359465_4 Protein of unknown function (DUF2490) - - - 0.000000000000000005804 93.0
HKD1_k127_4364089_0 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 341.0
HKD1_k127_4364089_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HKD1_k127_4364089_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005002 263.0
HKD1_k127_4364089_3 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004842 256.0
HKD1_k127_442259_0 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 394.0
HKD1_k127_442259_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
HKD1_k127_442259_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001019 290.0
HKD1_k127_442259_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007596 287.0
HKD1_k127_442259_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000001134 79.0
HKD1_k127_4432454_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 426.0
HKD1_k127_4432454_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000005002 158.0
HKD1_k127_4432454_2 Evidence 4 Homologs of previously reported genes of K02016 - - 0.000000000000000000000000000000000000005375 150.0
HKD1_k127_4432454_3 Single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000000000000005447 142.0
HKD1_k127_4432454_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000007752 127.0
HKD1_k127_4432454_5 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000686 66.0
HKD1_k127_4432454_6 containing protein - GO:0003008,GO:0003674,GO:0005488,GO:0005518,GO:0005575,GO:0005576,GO:0007600,GO:0007605,GO:0008150,GO:0008360,GO:0022603,GO:0022604,GO:0031012,GO:0032501,GO:0044421,GO:0044877,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050954,GO:0051128,GO:0065007,GO:0065008 - 0.00000001005 66.0
HKD1_k127_4434824_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000009236 238.0
HKD1_k127_4434824_1 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000004939 164.0
HKD1_k127_4434824_2 ABC transporter K02013 - 3.6.3.34 0.0000002175 63.0
HKD1_k127_4439522_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 467.0
HKD1_k127_4439522_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001518 232.0
HKD1_k127_4481073_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000192 227.0
HKD1_k127_4481073_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000133 151.0
HKD1_k127_4481073_2 integral membrane protein - - - 0.0000000000000000005991 98.0
HKD1_k127_4482030_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 370.0
HKD1_k127_4482030_1 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000232 242.0
HKD1_k127_4482030_3 Transport permease protein K01992 - - 0.000000000000000001682 86.0
HKD1_k127_4482150_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 361.0
HKD1_k127_4482150_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000004225 247.0
HKD1_k127_4482150_2 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.0000000000000000000000000000000001723 142.0
HKD1_k127_4493074_0 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
HKD1_k127_4493074_1 Ankyrin repeat K06867 - - 0.0000000000000000000001128 112.0
HKD1_k127_4493074_2 PFAM Peptidoglycan-binding domain 1 protein - - - 0.0000000000000003303 92.0
HKD1_k127_4503224_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1117.0
HKD1_k127_4503224_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 438.0
HKD1_k127_4504709_0 Amidohydrolase family - - - 4.585e-217 687.0
HKD1_k127_4504709_1 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000984 198.0
HKD1_k127_4504709_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000004219 115.0
HKD1_k127_4510120_0 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000000000000000000000000002214 222.0
HKD1_k127_4510120_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000007749 173.0
HKD1_k127_4510120_2 GGDEF domain - - - 0.00000000000000000000000000000008803 143.0
HKD1_k127_4510120_3 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000004113 72.0
HKD1_k127_4538613_0 TonB dependent receptor K02014 - - 7.008e-311 975.0
HKD1_k127_4538613_1 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002768 261.0
HKD1_k127_4538613_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000003924 209.0
HKD1_k127_4559641_0 lipopolysaccharide transport K22110 - - 4.269e-291 899.0
HKD1_k127_4559641_1 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 407.0
HKD1_k127_4565593_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
HKD1_k127_4565593_1 Tetratricopeptide repeat - - - 0.0000000107 62.0
HKD1_k127_4570124_0 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 319.0
HKD1_k127_4570124_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 265.0
HKD1_k127_4570124_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000002381 145.0
HKD1_k127_4570124_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000004129 137.0
HKD1_k127_4571092_0 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003931 263.0
HKD1_k127_4571092_1 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000198 204.0
HKD1_k127_4571092_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.00002895 57.0
HKD1_k127_4585316_0 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 408.0
HKD1_k127_4585316_1 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 336.0
HKD1_k127_4585316_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 320.0
HKD1_k127_4585316_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
HKD1_k127_4585316_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008507 274.0
HKD1_k127_4585316_5 IMG reference gene - - - 0.000000000000000000000000000000000000001807 166.0
HKD1_k127_4585316_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000007628 132.0
HKD1_k127_4585316_7 PFAM Pyrrolo-quinoline quinone - - - 0.00000000000000000000001115 112.0
HKD1_k127_4585316_8 COG1520 FOG WD40-like repeat - - - 0.0000003777 59.0
HKD1_k127_459225_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 410.0
HKD1_k127_459225_1 Polysaccharide export protein K01991,K20988 - - 0.000000000000000000000000000000000000000000000000000000000000000001455 242.0
HKD1_k127_459225_2 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000000000000005407 186.0
HKD1_k127_459225_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000009066 186.0
HKD1_k127_459225_4 KR domain K07124 - - 0.000000000000000000000000000000000000000001426 167.0
HKD1_k127_4596513_0 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 527.0
HKD1_k127_4596513_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 395.0
HKD1_k127_4596513_2 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 308.0
HKD1_k127_4602860_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 522.0
HKD1_k127_4602860_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 377.0
HKD1_k127_4602860_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 318.0
HKD1_k127_4602860_3 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 321.0
HKD1_k127_4602860_4 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000003968 208.0
HKD1_k127_4602860_5 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000001797 157.0
HKD1_k127_4602860_6 acetyltransferase - - - 0.00000000000000000000000002524 118.0
HKD1_k127_4602860_7 Beta-lactamase superfamily domain - - - 0.000002443 50.0
HKD1_k127_4649667_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 326.0
HKD1_k127_4649667_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002481 289.0
HKD1_k127_4649667_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006108 260.0
HKD1_k127_4649667_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000009961 141.0
HKD1_k127_4649667_4 STAS domain K06378 - - 0.000000002186 63.0
HKD1_k127_4663166_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000009535 199.0
HKD1_k127_4663166_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000004881 116.0
HKD1_k127_4663166_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000004583 95.0
HKD1_k127_4663292_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 485.0
HKD1_k127_4663292_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000006877 178.0
HKD1_k127_4663292_2 PFAM peptidase M48 Ste24p - - - 0.00000000000004347 81.0
HKD1_k127_468026_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000615 228.0
HKD1_k127_468026_1 Sporulation and spore germination - - - 0.00000000000000000000000001069 119.0
HKD1_k127_4684336_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 397.0
HKD1_k127_4684336_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000009147 161.0
HKD1_k127_4684336_2 PFAM CAAX amino terminal protease family K07052 - - 0.0000000000000001211 90.0
HKD1_k127_4684336_3 TIGRFAM TonB K03832 - - 0.000000000000001858 86.0
HKD1_k127_4689858_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003122 273.0
HKD1_k127_4689858_1 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000003547 167.0
HKD1_k127_4689858_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000007373 118.0
HKD1_k127_4689858_4 Transcriptional regulator, MarR family - - - 0.00000000000785 66.0
HKD1_k127_4693917_0 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 425.0
HKD1_k127_4693917_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 335.0
HKD1_k127_4693917_2 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000003614 203.0
HKD1_k127_4693917_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000006297 179.0
HKD1_k127_4719332_0 helicase activity - - - 1.797e-314 982.0
HKD1_k127_4719332_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
HKD1_k127_4719332_2 A-macroglobulin complement component - - - 0.000000000000000000000000000000000000000000000000000000000000006444 246.0
HKD1_k127_4719332_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000006503 145.0
HKD1_k127_4778972_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 305.0
HKD1_k127_4778972_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000001084 157.0
HKD1_k127_4782154_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001447 235.0
HKD1_k127_4782154_1 Thioredoxin - - - 0.0000000000000000000000000000000000000000000003487 178.0
HKD1_k127_4782154_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000001535 170.0
HKD1_k127_4782154_3 PKD domain K19668 - 3.2.1.91 0.0000000000003027 84.0
HKD1_k127_4782427_0 PFAM OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 569.0
HKD1_k127_4782427_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 354.0
HKD1_k127_4782427_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000002031 91.0
HKD1_k127_4782427_3 - - - - 0.000005631 55.0
HKD1_k127_4794406_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 421.0
HKD1_k127_4794406_1 UMP kinase activity K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 321.0
HKD1_k127_4794406_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005247 248.0
HKD1_k127_4794406_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000004276 201.0
HKD1_k127_4794406_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000531 147.0
HKD1_k127_4817532_0 PFAM GlcNAc-PI de-N-acetylase - - - 2.562e-220 703.0
HKD1_k127_4817532_1 Amidohydrolase family - - - 2.432e-198 638.0
HKD1_k127_4817532_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 595.0
HKD1_k127_4817532_3 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000006265 243.0
HKD1_k127_4817532_4 Tetratricopeptide repeat - - - 0.0000000265 67.0
HKD1_k127_482643_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 383.0
HKD1_k127_482643_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000005 131.0
HKD1_k127_482643_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000001452 89.0
HKD1_k127_4831370_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 589.0
HKD1_k127_4831370_1 Sodium/hydrogen exchanger family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 501.0
HKD1_k127_4831370_2 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001555 244.0
HKD1_k127_4831370_3 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000005152 123.0
HKD1_k127_4831370_4 cyclic nucleotide binding K01420,K10914 - - 0.0000000000008776 80.0
HKD1_k127_4832834_0 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 453.0
HKD1_k127_4832834_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 281.0
HKD1_k127_4832834_2 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006101 255.0
HKD1_k127_4832834_3 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000001604 110.0
HKD1_k127_4850371_0 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 292.0
HKD1_k127_4850371_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000007608 112.0
HKD1_k127_4854689_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 492.0
HKD1_k127_4854689_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003868 259.0
HKD1_k127_4854689_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000002337 235.0
HKD1_k127_4854689_3 threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000001905 210.0
HKD1_k127_4855683_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 381.0
HKD1_k127_4855683_1 - - - - 0.00000000000000000000000000000000000000005207 164.0
HKD1_k127_4855683_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000879 151.0
HKD1_k127_4855683_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000002257 150.0
HKD1_k127_4855683_4 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000004258 123.0
HKD1_k127_4861147_0 response regulator receiver K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000001443 231.0
HKD1_k127_4861147_1 histidine kinase HAMP region domain protein K07640 - 2.7.13.3 0.000000000000000000000000000000000000002833 163.0
HKD1_k127_4861147_2 ATP-independent chaperone mediated protein folding - - - 0.0002234 50.0
HKD1_k127_4868963_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1258.0
HKD1_k127_4868963_1 Phosphoesterase family - - - 2.355e-214 691.0
HKD1_k127_4868963_2 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 353.0
HKD1_k127_4868963_3 - - - - 0.000000000000000000000532 101.0
HKD1_k127_4868963_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000004236 109.0
HKD1_k127_4868963_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000373 82.0
HKD1_k127_4868963_6 Universal stress protein K06149 - - 0.0000000000002137 77.0
HKD1_k127_4868963_7 peptidase S58, DmpA - - - 0.000001946 57.0
HKD1_k127_4868963_8 pectate lyase - - - 0.00002046 53.0
HKD1_k127_4875479_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.264e-263 820.0
HKD1_k127_4875479_1 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000001101 114.0
HKD1_k127_4875479_2 Glycoside hydrolase family 44 - - - 0.00000000001473 74.0
HKD1_k127_4918564_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001581 262.0
HKD1_k127_4918564_1 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000005279 224.0
HKD1_k127_4918564_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000001852 173.0
HKD1_k127_4918564_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000002424 179.0
HKD1_k127_4918564_4 Tetratricopeptide repeats - - - 0.00000000000000000000000000008034 131.0
HKD1_k127_4918564_5 Domain of unknown function (DUF4412) - - - 0.000000006416 65.0
HKD1_k127_4918564_6 Penicillinase repressor - - - 0.00007765 49.0
HKD1_k127_4922710_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 554.0
HKD1_k127_4922710_1 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 397.0
HKD1_k127_4922710_10 - - - - 0.00000000000000000000000001139 113.0
HKD1_k127_4922710_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
HKD1_k127_4922710_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 331.0
HKD1_k127_4922710_4 region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 273.0
HKD1_k127_4922710_5 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
HKD1_k127_4922710_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000002629 201.0
HKD1_k127_4922710_7 - - - - 0.0000000000000000000000000000000000000000000000000003012 211.0
HKD1_k127_4922710_8 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000001157 187.0
HKD1_k127_4922710_9 Pkd domain containing protein - - - 0.000000000000000000000000000000000000001796 164.0
HKD1_k127_4929067_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.373e-205 644.0
HKD1_k127_4929067_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 528.0
HKD1_k127_4929067_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
HKD1_k127_4929067_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000005742 189.0
HKD1_k127_4929067_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000001993 165.0
HKD1_k127_4937942_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 519.0
HKD1_k127_4937942_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006362 276.0
HKD1_k127_4937942_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000003409 207.0
HKD1_k127_4937942_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000005984 190.0
HKD1_k127_4937942_5 Amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030,K09971 - - 0.0000000000000000000000005551 115.0
HKD1_k127_4937942_6 MacB-like periplasmic core domain - - - 0.00000000000000001481 96.0
HKD1_k127_4939398_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008019 276.0
HKD1_k127_4939398_1 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000001499 235.0
HKD1_k127_4940082_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 353.0
HKD1_k127_4940082_1 Acetylornithine deacetylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000005661 191.0
HKD1_k127_4940082_2 sequence-specific DNA binding K03719 - - 0.000000000000000000000000000000000000000000000000001034 187.0
HKD1_k127_4940082_3 cell wall organization K01448 - 3.5.1.28 0.000003255 59.0
HKD1_k127_4940082_4 - - - - 0.0002197 47.0
HKD1_k127_4947453_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 514.0
HKD1_k127_4947453_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000005892 201.0
HKD1_k127_4947453_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000001996 141.0
HKD1_k127_4947453_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000009091 61.0
HKD1_k127_4947453_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0001028 45.0
HKD1_k127_4960386_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
HKD1_k127_4960386_1 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000473 129.0
HKD1_k127_4960386_2 Glycosyltransferase like family 2 - - - 0.00000000000000007291 82.0
HKD1_k127_4960386_3 Glycosyltransferase like family 2 - - - 0.00005974 55.0
HKD1_k127_4972376_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1e-323 1004.0
HKD1_k127_4972376_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 360.0
HKD1_k127_4972376_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000278 156.0
HKD1_k127_4972376_3 Beta-lactamase class A K17836 - 3.5.2.6 0.000241 51.0
HKD1_k127_4977705_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 7.07e-279 891.0
HKD1_k127_4977705_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 456.0
HKD1_k127_4977705_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000003383 233.0
HKD1_k127_4977705_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000005099 229.0
HKD1_k127_4977705_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000001311 212.0
HKD1_k127_4977705_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000001724 59.0
HKD1_k127_4988691_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.136e-268 850.0
HKD1_k127_4988691_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 372.0
HKD1_k127_4988691_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 319.0
HKD1_k127_4988691_3 membrane - - - 0.0000000000000000000000000003797 117.0
HKD1_k127_4990023_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000008025 225.0
HKD1_k127_4990023_1 Autotransporter beta-domain - - - 0.0000000000000000000000000000008158 139.0
HKD1_k127_5021513_0 Amidohydrolase family - - - 2.924e-221 701.0
HKD1_k127_5021513_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 493.0
HKD1_k127_5021513_2 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 355.0
HKD1_k127_5021513_3 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000008666 186.0
HKD1_k127_5021513_4 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000000000000000000000001425 134.0
HKD1_k127_5021513_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000205 124.0
HKD1_k127_5021513_6 Domain of unknown function (DU1801) - - - 0.000000000000006059 85.0
HKD1_k127_5045180_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 6.821e-198 623.0
HKD1_k127_5045180_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 420.0
HKD1_k127_5045180_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000005965 194.0
HKD1_k127_5045180_3 CorA-like Mg2+ transporter protein K03284 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000001281 74.0
HKD1_k127_5053449_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001308 192.0
HKD1_k127_5053449_1 Smr domain - - - 0.0000000000000000000002394 98.0
HKD1_k127_5053449_2 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000001315 69.0
HKD1_k127_5068768_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 497.0
HKD1_k127_5068768_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 396.0
HKD1_k127_5068768_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 383.0
HKD1_k127_5068768_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000759 276.0
HKD1_k127_5068768_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.0000000000000000000002003 99.0
HKD1_k127_5070791_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003686 294.0
HKD1_k127_5070791_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000002807 236.0
HKD1_k127_5072874_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 385.0
HKD1_k127_5072874_1 Phosphate acyltransferases - - - 0.0000000000000005136 89.0
HKD1_k127_5072874_2 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000001543 80.0
HKD1_k127_5077195_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
HKD1_k127_5077195_1 Pfam ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001911 269.0
HKD1_k127_5077195_2 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004205 265.0
HKD1_k127_5077195_3 PFAM Cobalt transport protein K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000238 200.0
HKD1_k127_5077195_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000000009374 110.0
HKD1_k127_5077195_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000001461 95.0
HKD1_k127_5094161_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 440.0
HKD1_k127_5094161_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 406.0
HKD1_k127_5094161_10 Trypsin-like peptidase domain - - - 0.00002859 56.0
HKD1_k127_5094161_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 398.0
HKD1_k127_5094161_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 303.0
HKD1_k127_5094161_4 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HKD1_k127_5094161_5 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001722 273.0
HKD1_k127_5094161_6 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000563 276.0
HKD1_k127_5094161_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000001209 202.0
HKD1_k127_5094161_8 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000001134 170.0
HKD1_k127_5094161_9 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000003113 85.0
HKD1_k127_5100001_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 455.0
HKD1_k127_5100001_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 309.0
HKD1_k127_5100001_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
HKD1_k127_5100001_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001083 258.0
HKD1_k127_5100001_4 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
HKD1_k127_5104269_0 OPT oligopeptide transporter protein - - - 5.195e-307 953.0
HKD1_k127_5104269_1 ammonia-lyase activity K01745 - 4.3.1.3 2.511e-259 806.0
HKD1_k127_5104269_2 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 559.0
HKD1_k127_5104269_3 Leukotriene A-4 hydrolase K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 505.0
HKD1_k127_5104269_4 - - - - 0.000000000000000000000000002375 125.0
HKD1_k127_5104269_5 - - - - 0.00000000000000000000000001543 117.0
HKD1_k127_5104269_6 BNR Asp-box repeat - - - 0.00000002176 63.0
HKD1_k127_5128507_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 4.729e-204 643.0
HKD1_k127_5128507_1 PFAM Rieske 2Fe-2S domain protein K00479,K00499,K05708 - 1.14.12.19,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 520.0
HKD1_k127_5128507_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000001098 119.0
HKD1_k127_5128507_3 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000002814 107.0
HKD1_k127_5130678_0 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 479.0
HKD1_k127_5130678_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 428.0
HKD1_k127_5131197_0 proline dipeptidase activity K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 520.0
HKD1_k127_5131197_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
HKD1_k127_5131197_2 PFAM Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000005067 154.0
HKD1_k127_5131446_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 5.557e-198 647.0
HKD1_k127_5131446_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 484.0
HKD1_k127_5131446_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 305.0
HKD1_k127_5132147_0 Aminotransferase class-III - - - 3.987e-206 650.0
HKD1_k127_5132147_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000004247 177.0
HKD1_k127_5132147_2 oligosaccharyl transferase activity - - - 0.0000000000001244 85.0
HKD1_k127_5137064_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002695 250.0
HKD1_k127_5148078_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 483.0
HKD1_k127_5148078_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000001665 167.0
HKD1_k127_5148078_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000001766 169.0
HKD1_k127_5155453_0 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 263.0
HKD1_k127_5155453_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
HKD1_k127_5155453_2 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
HKD1_k127_5155453_3 Membrane - - - 0.0000000000000000000000000000000000000000000000000007083 198.0
HKD1_k127_5156724_0 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 381.0
HKD1_k127_5156724_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 380.0
HKD1_k127_5156724_2 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000002243 248.0
HKD1_k127_5156724_3 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000001131 170.0
HKD1_k127_5156724_4 - - - - 0.000000000007355 74.0
HKD1_k127_5175489_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 533.0
HKD1_k127_5175489_1 HlyD membrane-fusion protein of T1SS K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
HKD1_k127_5175489_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000002506 61.0
HKD1_k127_5202870_0 Peptidase S8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 400.0
HKD1_k127_5202870_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000001303 120.0
HKD1_k127_5202870_2 domain protein K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000002348 105.0
HKD1_k127_5202870_3 Thiol peroxidase K03564 - 1.11.1.15 0.00000000001153 70.0
HKD1_k127_5209273_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 477.0
HKD1_k127_5209273_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000003432 164.0
HKD1_k127_5209273_2 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000001093 129.0
HKD1_k127_5209273_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000001767 126.0
HKD1_k127_5209273_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000002554 91.0
HKD1_k127_5212046_0 PFAM Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 317.0
HKD1_k127_5212046_1 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
HKD1_k127_5212046_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
HKD1_k127_5212046_3 RNA recognition motif - - - 0.00000000000000000000001147 107.0
HKD1_k127_5239107_0 lipopolysaccharide transport K22110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 446.0
HKD1_k127_5239107_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000001547 162.0
HKD1_k127_525008_0 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 368.0
HKD1_k127_525008_1 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000003582 161.0
HKD1_k127_525008_2 Histidine kinase - - - 0.0000000000000000000000000625 108.0
HKD1_k127_5283481_0 PFAM Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 581.0
HKD1_k127_5283481_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 302.0
HKD1_k127_5283481_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001561 241.0
HKD1_k127_5283481_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
HKD1_k127_5283481_4 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000008117 157.0
HKD1_k127_5297021_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 405.0
HKD1_k127_5297021_1 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 296.0
HKD1_k127_5297021_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000001429 239.0
HKD1_k127_5297021_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000007448 212.0
HKD1_k127_5297021_4 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000103 171.0
HKD1_k127_5297021_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000006218 141.0
HKD1_k127_5297021_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000009344 132.0
HKD1_k127_5297021_7 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000002906 121.0
HKD1_k127_5297021_8 PFAM Lipid A - - - 0.00000000000000000003097 98.0
HKD1_k127_5300438_0 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000061 252.0
HKD1_k127_5300438_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006657 228.0
HKD1_k127_5300438_2 peptidyl-tyrosine sulfation - - - 0.00000000000000007564 86.0
HKD1_k127_5301675_0 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 410.0
HKD1_k127_5301675_1 Belongs to the N-Me-Phe pilin family - - - 0.000000000001691 76.0
HKD1_k127_5301675_2 Bacterial membrane protein YfhO - - - 0.00000009866 63.0
HKD1_k127_5307507_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 3.817e-219 694.0
HKD1_k127_5307507_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 368.0
HKD1_k127_5307507_2 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 364.0
HKD1_k127_5307507_3 transcriptional regulator K09017 - - 0.00000000000000002919 89.0
HKD1_k127_5307507_4 - K14645 - - 0.00000000000000003534 87.0
HKD1_k127_5307507_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0004132 43.0
HKD1_k127_5311068_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 306.0
HKD1_k127_5311068_1 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 291.0
HKD1_k127_5311068_2 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001664 241.0
HKD1_k127_5311068_3 GYD domain - - - 0.00000000000000000000000000000000006604 137.0
HKD1_k127_5316929_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 453.0
HKD1_k127_5316929_1 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001875 301.0
HKD1_k127_5323973_0 cellulose binding - - - 1.3e-218 683.0
HKD1_k127_5323973_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 340.0
HKD1_k127_5323973_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000001429 240.0
HKD1_k127_5323973_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000003408 152.0
HKD1_k127_5323973_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000007812 94.0
HKD1_k127_5323973_5 - - - - 0.00000000008804 64.0
HKD1_k127_533540_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 604.0
HKD1_k127_533540_1 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000001699 146.0
HKD1_k127_533540_2 Glycosyltransferase Family 4 K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000002477 94.0
HKD1_k127_533540_3 - - - - 0.0000000001461 64.0
HKD1_k127_533540_4 protein with a von Willebrand factor type A (vWA) domain K07114 - - 0.0000003441 56.0
HKD1_k127_5355101_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001207 250.0
HKD1_k127_5355101_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001997 240.0
HKD1_k127_5356330_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 327.0
HKD1_k127_5356330_1 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000003179 214.0
HKD1_k127_5356330_2 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000001207 173.0
HKD1_k127_5359028_0 Protein tyrosine kinase - - - 3.599e-210 683.0
HKD1_k127_5359028_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000003725 57.0
HKD1_k127_5360663_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 407.0
HKD1_k127_5360663_1 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000696 248.0
HKD1_k127_5360663_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000001888 198.0
HKD1_k127_5360663_3 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000001741 201.0
HKD1_k127_5360663_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000007142 202.0
HKD1_k127_5360663_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000006127 150.0
HKD1_k127_5360663_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000008403 143.0
HKD1_k127_5360663_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000007899 127.0
HKD1_k127_5365371_0 penicillin amidase K01434 - 3.5.1.11 3.057e-317 992.0
HKD1_k127_5365371_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002266 282.0
HKD1_k127_5370733_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000004857 160.0
HKD1_k127_5376161_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 399.0
HKD1_k127_5376161_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006474 266.0
HKD1_k127_5376161_2 - - - - 0.0000000000000000001428 97.0
HKD1_k127_5381933_0 transporter, DctM subunit K11690 - - 5.54e-214 682.0
HKD1_k127_5381933_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 369.0
HKD1_k127_5381933_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
HKD1_k127_5381933_4 Notum pectinacetylesterase 2 K19882 GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005615,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0043009,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699 3.1.1.98 0.0000000000000000000000000001048 124.0
HKD1_k127_5381933_5 Alpha beta hydrolase - - - 0.0000000000000000000006605 99.0
HKD1_k127_538358_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 389.0
HKD1_k127_538358_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
HKD1_k127_538358_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004543 242.0
HKD1_k127_5386724_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 446.0
HKD1_k127_5386724_1 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
HKD1_k127_5386724_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 282.0
HKD1_k127_5386724_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000002851 123.0
HKD1_k127_5386724_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000004018 108.0
HKD1_k127_5386724_5 Histidine kinase K07646 - 2.7.13.3 0.000000000287 67.0
HKD1_k127_5403641_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 398.0
HKD1_k127_5403641_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001492 242.0
HKD1_k127_5403641_2 oligosaccharyl transferase activity K19003,K20327 - 2.4.1.336 0.00000000000000000000000000000000000001389 162.0
HKD1_k127_5403641_3 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.0000000000000000000000000000002131 142.0
HKD1_k127_5403641_4 PFAM TPR repeat-containing protein - - - 0.0000004997 61.0
HKD1_k127_5409177_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 564.0
HKD1_k127_5409177_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 481.0
HKD1_k127_5409177_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000002489 86.0
HKD1_k127_5427691_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 321.0
HKD1_k127_5427691_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000002182 191.0
HKD1_k127_5427691_2 integral membrane protein K00728 - 2.4.1.109 0.000000000000000000000005131 118.0
HKD1_k127_5427691_4 PFAM Tetratricopeptide repeat - - - 0.00003289 56.0
HKD1_k127_5433290_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 574.0
HKD1_k127_5433290_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 263.0
HKD1_k127_5433290_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000005184 169.0
HKD1_k127_5433290_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000009043 136.0
HKD1_k127_5433290_4 Glycosyltransferase like family 2 - - - 0.00000000000000000002929 102.0
HKD1_k127_5433290_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00006212 48.0
HKD1_k127_5451857_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 386.0
HKD1_k127_5451857_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
HKD1_k127_5451857_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003231 250.0
HKD1_k127_5451857_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000701 198.0
HKD1_k127_5451857_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000936 134.0
HKD1_k127_5451857_5 TIGRFAM ribosomal protein L17 K02879 - - 0.00000000000000000000000000003598 121.0
HKD1_k127_5457758_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.072e-204 655.0
HKD1_k127_5457758_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 309.0
HKD1_k127_5457758_10 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000007674 83.0
HKD1_k127_5457758_11 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.00000000000000002097 93.0
HKD1_k127_5457758_12 peptidyl-tyrosine sulfation - - - 0.000000000000118 80.0
HKD1_k127_5457758_13 Methyltransferase domain - - - 0.0000001281 62.0
HKD1_k127_5457758_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 315.0
HKD1_k127_5457758_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 308.0
HKD1_k127_5457758_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002223 295.0
HKD1_k127_5457758_5 PFAM ParB domain protein nuclease K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003352 252.0
HKD1_k127_5457758_6 - - - - 0.0000000000000000000002948 111.0
HKD1_k127_5457758_7 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000003441 96.0
HKD1_k127_5457758_8 Polymer-forming cytoskeletal - - - 0.0000000000000000003167 92.0
HKD1_k127_5457758_9 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000005753 92.0
HKD1_k127_5463467_0 Domain of unknown function (DUF5117) - - - 3.821e-317 988.0
HKD1_k127_5467707_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.738e-212 668.0
HKD1_k127_5467707_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 371.0
HKD1_k127_5467707_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000007658 226.0
HKD1_k127_5467707_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000001676 85.0
HKD1_k127_5467707_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0008163 48.0
HKD1_k127_5476816_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 563.0
HKD1_k127_5476816_1 GlcNAc-PI de-N-acetylase - - - 0.0000001027 58.0
HKD1_k127_5476816_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000005871 56.0
HKD1_k127_5481333_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.223e-278 869.0
HKD1_k127_5492494_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1046.0
HKD1_k127_5492494_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 456.0
HKD1_k127_5492494_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 301.0
HKD1_k127_5492494_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000008949 263.0
HKD1_k127_5492494_4 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
HKD1_k127_5495050_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 520.0
HKD1_k127_5495050_1 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 382.0
HKD1_k127_5495050_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 355.0
HKD1_k127_5495050_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 291.0
HKD1_k127_5495050_4 RNA signal recognition particle 4.5S RNA - - - 0.000000000000000000000000000000000000000000001811 169.0
HKD1_k127_5495050_5 Transposase K07491 - - 0.000000000000000000000000000000000000000000645 162.0
HKD1_k127_5506510_0 Alpha-amylase domain K01176 - 3.2.1.1 3.6e-214 684.0
HKD1_k127_5506510_1 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000401 219.0
HKD1_k127_5506510_2 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000005698 194.0
HKD1_k127_5506510_3 Histidine kinase - - - 0.000000000006497 79.0
HKD1_k127_5524031_0 Putative cell wall binding repeat 2 - - - 0.0000000000000000000000000000000000000000000000000000000000874 225.0
HKD1_k127_5524031_1 Peptidoglycan-binding domain 1 protein K17733 - - 0.00000000007822 76.0
HKD1_k127_553381_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 312.0
HKD1_k127_553381_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 303.0
HKD1_k127_553381_2 proline dipeptidase activity K06106,K14213 GO:0003674,GO:0003824,GO:0004177,GO:0004180,GO:0004181,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008239,GO:0009987,GO:0016787,GO:0019538,GO:0019752,GO:0031974,GO:0031981,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000003657 223.0
HKD1_k127_553381_3 PBS lyase HEAT-like repeat - - - 0.00000004177 65.0
HKD1_k127_553381_4 Psort location Cytoplasmic, score - - - 0.0000002249 59.0
HKD1_k127_5537427_0 FAD linked oxidase - - - 4.555e-232 725.0
HKD1_k127_5537427_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000007617 197.0
HKD1_k127_5537427_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001153 155.0
HKD1_k127_5540792_0 Sortilin, neurotensin receptor 3, - - - 1.827e-233 742.0
HKD1_k127_5558075_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 322.0
HKD1_k127_5558075_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 310.0
HKD1_k127_5558075_2 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000002098 209.0
HKD1_k127_5563760_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 446.0
HKD1_k127_5563760_1 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000006319 184.0
HKD1_k127_5563760_2 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000003147 167.0
HKD1_k127_5563760_3 Hemerythrin HHE cation binding - - - 0.000000000000000000000000000712 121.0
HKD1_k127_5574929_0 ABC transporter K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002842 279.0
HKD1_k127_5574929_1 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000004358 132.0
HKD1_k127_5583828_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 1.316e-197 636.0
HKD1_k127_5583828_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 486.0
HKD1_k127_5583828_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001374 256.0
HKD1_k127_5583828_3 - - - - 0.000000000000000000000000000000000000000003244 159.0
HKD1_k127_5583828_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000003655 131.0
HKD1_k127_5583828_5 cAMP biosynthetic process - - - 0.0000002101 55.0
HKD1_k127_5583828_6 - - - - 0.00001882 57.0
HKD1_k127_5584826_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 493.0
HKD1_k127_5584826_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
HKD1_k127_5584826_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 345.0
HKD1_k127_5584826_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 291.0
HKD1_k127_5584826_4 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001656 256.0
HKD1_k127_5584826_5 LysR substrate binding domain K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007353 247.0
HKD1_k127_5584826_6 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000004467 186.0
HKD1_k127_5584826_7 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000005306 183.0
HKD1_k127_5584826_8 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000001222 139.0
HKD1_k127_5584826_9 Belongs to the DegT DnrJ EryC1 family - - - 0.00000001224 61.0
HKD1_k127_5585347_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
HKD1_k127_5585347_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000817 175.0
HKD1_k127_5585347_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000008448 160.0
HKD1_k127_5585347_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000002953 155.0
HKD1_k127_5585347_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000001369 144.0
HKD1_k127_5585347_5 Yqey-like protein K09117 - - 0.000000000000000000001607 100.0
HKD1_k127_5592177_0 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 346.0
HKD1_k127_5592177_1 Elongator protein 3, MiaB family, Radical SAM K06871,K21936 - 2.1.1.342 0.00000000000000000000000000000000000000000000000000000000000000000000002128 259.0
HKD1_k127_5592177_2 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000002269 239.0
HKD1_k127_5592177_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000001276 164.0
HKD1_k127_5594369_0 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 477.0
HKD1_k127_5594369_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000109 184.0
HKD1_k127_5594369_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000003477 160.0
HKD1_k127_5594369_3 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000006097 136.0
HKD1_k127_5594369_4 Helix-turn-helix domain - - - 0.00000000000000000000000000005096 119.0
HKD1_k127_5594369_5 TonB-linked outer membrane protein, SusC RagA family - - - 0.00003428 49.0
HKD1_k127_5594828_0 succinyl-diaminopimelate desuccinylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 561.0
HKD1_k127_5594828_1 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000000000000000000000000000001169 154.0
HKD1_k127_5597402_0 Surface antigen K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 431.0
HKD1_k127_5600401_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 441.0
HKD1_k127_5600401_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 405.0
HKD1_k127_5600401_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
HKD1_k127_5600401_3 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 308.0
HKD1_k127_5608370_0 cellulase activity - - - 5.449e-259 848.0
HKD1_k127_5608370_1 IMS family HHH motif K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 325.0
HKD1_k127_5608370_10 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000001466 53.0
HKD1_k127_5608370_2 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001245 263.0
HKD1_k127_5608370_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000001871 220.0
HKD1_k127_5608370_4 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000000000000001032 159.0
HKD1_k127_5608370_5 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000001819 137.0
HKD1_k127_5608370_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000004891 85.0
HKD1_k127_5608370_7 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000000003429 94.0
HKD1_k127_5608370_8 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000004376 84.0
HKD1_k127_5610134_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.084e-270 858.0
HKD1_k127_5610134_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 491.0
HKD1_k127_5610134_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000264 63.0
HKD1_k127_5610134_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 443.0
HKD1_k127_5610134_3 Transferrin receptor-like dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 419.0
HKD1_k127_5610134_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD1_k127_5610134_5 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 319.0
HKD1_k127_5610134_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000009946 226.0
HKD1_k127_5610134_7 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000003858 166.0
HKD1_k127_5610134_8 - - - - 0.000000000000000000004038 102.0
HKD1_k127_5610134_9 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000001097 74.0
HKD1_k127_5611867_0 Amidohydrolase family K06015 - 3.5.1.81 6.266e-240 753.0
HKD1_k127_5611867_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 358.0
HKD1_k127_5611867_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 349.0
HKD1_k127_5621803_0 AMP-binding enzyme K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 364.0
HKD1_k127_5621803_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 295.0
HKD1_k127_5621803_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000002662 182.0
HKD1_k127_5621803_3 membrane - - - 0.000000000000000000000000000000000000000002767 166.0
HKD1_k127_5631122_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.396e-318 988.0
HKD1_k127_5631122_1 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 6.793e-282 885.0
HKD1_k127_5631122_10 - - - - 0.00000000000000002605 86.0
HKD1_k127_5631122_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 431.0
HKD1_k127_5631122_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 374.0
HKD1_k127_5631122_4 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
HKD1_k127_5631122_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 301.0
HKD1_k127_5631122_6 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 291.0
HKD1_k127_5631122_7 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002135 276.0
HKD1_k127_5631122_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000002638 220.0
HKD1_k127_5631122_9 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000001235 186.0
HKD1_k127_5633577_0 Belongs to the amidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 437.0
HKD1_k127_5633577_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000002262 234.0
HKD1_k127_5633577_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000008194 168.0
HKD1_k127_5633577_3 RNA methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000003882 83.0
HKD1_k127_5635777_0 protein kinase activity K07180 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0 1031.0
HKD1_k127_5635777_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 539.0
HKD1_k127_5635777_2 SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 344.0
HKD1_k127_5635777_3 PFAM SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 318.0
HKD1_k127_5635777_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
HKD1_k127_5635777_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000006419 117.0
HKD1_k127_5635777_6 Cache domain - - - 0.0000000002231 68.0
HKD1_k127_5650246_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 349.0
HKD1_k127_5650246_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 341.0
HKD1_k127_5650246_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000005622 238.0
HKD1_k127_5650246_3 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000001993 168.0
HKD1_k127_5650246_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000249 164.0
HKD1_k127_5650246_5 Tetratricopeptide repeat - - - 0.0000000000001778 81.0
HKD1_k127_5650246_6 Methyltransferase domain - - - 0.0000000000264 75.0
HKD1_k127_5650246_7 Roadblock/LC7 domain - - - 0.0000001406 57.0
HKD1_k127_5652243_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.077e-249 777.0
HKD1_k127_5652243_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 565.0
HKD1_k127_5652243_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000001845 187.0
HKD1_k127_5652243_3 Biotin-requiring enzyme - - - 0.00000000000000000005422 98.0
HKD1_k127_5652243_4 Protein of unknown function (DUF721) - - - 0.000001756 53.0
HKD1_k127_5655061_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 486.0
HKD1_k127_5655061_1 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000004259 116.0
HKD1_k127_5655061_2 - - - - 0.000000000000001597 81.0
HKD1_k127_5684000_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 1.039e-199 640.0
HKD1_k127_5684000_1 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 475.0
HKD1_k127_5684000_2 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 340.0
HKD1_k127_5684000_3 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000000000000000000000000005349 173.0
HKD1_k127_5700998_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 447.0
HKD1_k127_5700998_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HKD1_k127_5700998_2 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 329.0
HKD1_k127_5700998_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000007549 232.0
HKD1_k127_5700998_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000007635 153.0
HKD1_k127_5700998_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000000000000009539 119.0
HKD1_k127_5700998_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000002005 96.0
HKD1_k127_5706760_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 334.0
HKD1_k127_5706760_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 304.0
HKD1_k127_5706760_2 RNA recognition motif - - - 0.000000000000000000000004565 108.0
HKD1_k127_5709270_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 420.0
HKD1_k127_5709270_1 alginic acid biosynthetic process K20276 - - 0.000000000000000000000000000000000000000000000000000000003341 213.0
HKD1_k127_5709270_2 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000001844 134.0
HKD1_k127_5709270_3 PFAM HD domain - - - 0.0000000000000000000000000009255 120.0
HKD1_k127_5709270_4 Belongs to the ompA family - - - 0.00000000000000000000000009731 119.0
HKD1_k127_5714038_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 406.0
HKD1_k127_5714038_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 407.0
HKD1_k127_5714038_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
HKD1_k127_5714038_3 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000244 187.0
HKD1_k127_5714038_4 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000004699 164.0
HKD1_k127_5735479_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 544.0
HKD1_k127_5735479_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 329.0
HKD1_k127_5735479_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000431 190.0
HKD1_k127_5735479_3 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000767 173.0
HKD1_k127_5735479_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000006488 154.0
HKD1_k127_5735479_5 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000001045 121.0
HKD1_k127_5735479_6 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000123 124.0
HKD1_k127_5735479_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000002389 92.0
HKD1_k127_5735479_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000002841 74.0
HKD1_k127_5740458_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 598.0
HKD1_k127_5752470_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 295.0
HKD1_k127_5752470_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
HKD1_k127_5752470_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000009403 177.0
HKD1_k127_5752470_3 outer membrane autotransporter barrel domain protein - - - 0.0000006183 58.0
HKD1_k127_5752665_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 581.0
HKD1_k127_5752665_1 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000007586 164.0
HKD1_k127_5752665_2 Pkd domain containing protein K12567 - 2.7.11.1 0.000000000000000000000002286 119.0
HKD1_k127_5754160_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 315.0
HKD1_k127_5754160_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000004198 87.0
HKD1_k127_5755958_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 5.256e-228 718.0
HKD1_k127_5755958_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.000000000000000000000000000000000000002323 152.0
HKD1_k127_5767612_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 538.0
HKD1_k127_5767612_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002774 287.0
HKD1_k127_5767612_2 domain, Protein - - - 0.00000000000000000000000000000000000000000002758 180.0
HKD1_k127_5767612_3 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000001954 145.0
HKD1_k127_5767612_4 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.00000001674 63.0
HKD1_k127_5768795_0 Bacterial protein of unknown function (DUF885) - - - 8.735e-230 724.0
HKD1_k127_5768795_1 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 320.0
HKD1_k127_5768795_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001743 302.0
HKD1_k127_5768795_3 Multicopper oxidase - - - 0.000000000000000000000000000000000000001524 152.0
HKD1_k127_5778058_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 498.0
HKD1_k127_5778058_1 peptidylprolyl isomerase, FKBP-type K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000006486 199.0
HKD1_k127_5778058_2 - - - - 0.0000000000000000000000000000000000000000001644 167.0
HKD1_k127_5778058_3 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000001463 158.0
HKD1_k127_5778058_4 S-layer homology domain - - - 0.0000000002129 73.0
HKD1_k127_5787876_0 Belongs to the peptidase M16 family K07263 - - 0.0 1047.0
HKD1_k127_5787876_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.743e-245 769.0
HKD1_k127_5787876_2 chaperone-mediated protein folding - - - 0.00000003393 57.0
HKD1_k127_5819014_0 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000007032 184.0
HKD1_k127_5819014_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000002634 153.0
HKD1_k127_5819014_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000319 108.0
HKD1_k127_5819398_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 598.0
HKD1_k127_5819398_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 534.0
HKD1_k127_5819398_2 ATPase-coupled phosphate ion transmembrane transporter activity K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
HKD1_k127_5819398_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane K09476 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 324.0
HKD1_k127_5819398_4 Phosphate ABC transporter, periplasmic phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000002137 149.0
HKD1_k127_5826384_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 432.0
HKD1_k127_5826384_1 ZIP Zinc transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000305 236.0
HKD1_k127_5826384_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000003544 209.0
HKD1_k127_5826384_3 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000003186 184.0
HKD1_k127_5826384_4 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000002392 152.0
HKD1_k127_5826384_5 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000002953 141.0
HKD1_k127_5829752_0 cellulose binding - - - 0.0 1303.0
HKD1_k127_5829752_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000001592 224.0
HKD1_k127_5857696_0 Heat shock 70 kDa protein K04043 - - 8.681e-221 700.0
HKD1_k127_5857696_1 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 376.0
HKD1_k127_5857696_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002646 272.0
HKD1_k127_5857696_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000004824 149.0
HKD1_k127_5857696_4 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000004969 136.0
HKD1_k127_5857696_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000002754 113.0
HKD1_k127_5857696_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000007816 101.0
HKD1_k127_5857696_7 DivIVA protein K04074 - - 0.0000000000000000009225 92.0
HKD1_k127_5857696_8 Cytochrome c554 and c-prime - - - 0.000000000000002145 89.0
HKD1_k127_5857696_9 DUF167 K09131 - - 0.0000000000000107 79.0
HKD1_k127_5864328_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 4.607e-248 787.0
HKD1_k127_5864328_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 492.0
HKD1_k127_5864328_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000001674 210.0
HKD1_k127_5864328_3 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000001484 199.0
HKD1_k127_5864328_4 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000001158 160.0
HKD1_k127_5864328_5 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000005133 107.0
HKD1_k127_5870784_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 461.0
HKD1_k127_5870784_1 thiolester hydrolase activity K06889 - - 0.0000000000000001062 89.0
HKD1_k127_5871943_0 GXGXG motif - - - 1.502e-270 859.0
HKD1_k127_5871943_1 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 605.0
HKD1_k127_5889117_0 TIGRFAM YidE YbjL duplication K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 475.0
HKD1_k127_5889117_1 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 321.0
HKD1_k127_5889117_2 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000002706 226.0
HKD1_k127_5889117_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000282 98.0
HKD1_k127_5889117_4 Plasmid stabilization system K19092 - - 0.0000000000000004418 81.0
HKD1_k127_5889117_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000003872 76.0
HKD1_k127_5889117_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000005152 77.0
HKD1_k127_5889117_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000005027 61.0
HKD1_k127_5889117_8 Bacterial antitoxin of type II TA system, VapB - - - 0.000001024 53.0
HKD1_k127_5897866_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 360.0
HKD1_k127_5897866_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001316 276.0
HKD1_k127_5897866_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000001631 134.0
HKD1_k127_5897866_3 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000006753 120.0
HKD1_k127_5897866_4 - - - - 0.000000000000003308 80.0
HKD1_k127_5897866_5 DnaJ molecular chaperone homology domain - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0003502 49.0
HKD1_k127_5905681_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000002389 205.0
HKD1_k127_5905681_1 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000002765 165.0
HKD1_k127_5905681_2 tetraacyldisaccharide 4'-kinase activity K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.0000000000000000000000000000000000003362 150.0
HKD1_k127_5905681_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000002199 63.0
HKD1_k127_5924205_0 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 471.0
HKD1_k127_5924205_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 402.0
HKD1_k127_5924205_2 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 392.0
HKD1_k127_5924205_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 333.0
HKD1_k127_5924205_4 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000002971 149.0
HKD1_k127_5924205_5 ethanolamine catabolic process - - - 0.00000000000000000000000000000000002051 137.0
HKD1_k127_5936973_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 537.0
HKD1_k127_5936973_1 potassium ion transmembrane transporter activity K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 338.0
HKD1_k127_5936973_2 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 314.0
HKD1_k127_5936973_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000005704 239.0
HKD1_k127_5936973_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002596 215.0
HKD1_k127_5936973_5 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0009086 50.0
HKD1_k127_5937028_0 Involved in the tonB-independent uptake of proteins - - - 6.745e-219 706.0
HKD1_k127_5937028_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 339.0
HKD1_k127_5938460_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 529.0
HKD1_k127_5938460_1 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 297.0
HKD1_k127_5938460_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000003722 210.0
HKD1_k127_5938460_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000002686 117.0
HKD1_k127_5938460_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000007458 110.0
HKD1_k127_5951300_0 Type III K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 533.0
HKD1_k127_5951300_1 FliP family K03226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006201 275.0
HKD1_k127_5951300_2 Type III K03223 - - 0.000000000000000000007002 100.0
HKD1_k127_5951300_3 Role in flagellar biosynthesis K02420 - - 0.0000000000000004903 80.0
HKD1_k127_5951300_4 YscO-like protein - - - 0.0000000000001144 77.0
HKD1_k127_5951300_5 type III secretion apparatus lipoprotein, YscJ HrcJ family K03222 - - 0.000008682 53.0
HKD1_k127_5951300_6 PFAM Flagellar hook-length control protein K02414 - - 0.000121 53.0
HKD1_k127_5951300_7 type III secretion inner membrane protein SctT K03228 - - 0.0002654 48.0
HKD1_k127_5955434_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
HKD1_k127_5955434_1 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003495 278.0
HKD1_k127_5955434_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000001952 164.0
HKD1_k127_5955434_3 - K01992 - - 0.0000007924 55.0
HKD1_k127_5975836_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 528.0
HKD1_k127_5975836_1 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
HKD1_k127_5975836_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 310.0
HKD1_k127_5975836_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
HKD1_k127_5975836_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000001749 243.0
HKD1_k127_5975836_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000001536 203.0
HKD1_k127_6001268_0 peptidase activity, acting on L-amino acid peptides K14647,K20276,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001217 260.0
HKD1_k127_6001268_1 membrane organization - - - 0.0000000000000000000000000000000139 139.0
HKD1_k127_6019081_0 Oxidoreductase - - - 1.136e-237 740.0
HKD1_k127_6019081_1 Glycine cleavage T-protein C-terminal barrel domain - - - 6.378e-200 628.0
HKD1_k127_6019081_2 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000001646 194.0
HKD1_k127_6019081_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000009614 148.0
HKD1_k127_6019081_5 Putative peptidoglycan binding domain - - - 0.000007938 59.0
HKD1_k127_6022722_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 631.0
HKD1_k127_6022722_1 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 387.0
HKD1_k127_6022722_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 334.0
HKD1_k127_6022722_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 331.0
HKD1_k127_6022722_4 spore germination - - - 0.0000000000000000000000000000000000001233 151.0
HKD1_k127_6022722_5 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000001142 156.0
HKD1_k127_6022722_6 membrane K08978 - - 0.0000000000000000000000000002174 121.0
HKD1_k127_6022722_7 Fibronectin type 3 domain - - - 0.000000000000000002034 102.0
HKD1_k127_6022722_8 YdjC-like protein K03478 - 3.5.1.105 0.00000000000001364 78.0
HKD1_k127_6025286_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 1.987e-250 781.0
HKD1_k127_6025286_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 289.0
HKD1_k127_6025872_0 Permease family K06901 - - 0.0000000000000000000000000000000004833 134.0
HKD1_k127_6025872_1 Family 5 K02035 - - 0.00000000000000000000000001761 116.0
HKD1_k127_6025872_2 the current gene model (or a revised gene model) may contain a - - - 0.000000000000001239 90.0
HKD1_k127_6027531_0 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 378.0
HKD1_k127_6027531_1 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 342.0
HKD1_k127_6027531_2 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
HKD1_k127_6027531_3 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000000000001043 207.0
HKD1_k127_6027531_4 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000004522 157.0
HKD1_k127_6027531_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000001099 146.0
HKD1_k127_6027531_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000006325 96.0
HKD1_k127_6027531_7 - - - - 0.0000000000000000000008328 100.0
HKD1_k127_6035563_0 transglycosylase K08309 - - 0.00000000000000000000000002871 123.0
HKD1_k127_6035563_1 energy transducer activity - - - 0.000000000002457 78.0
HKD1_k127_6055139_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 464.0
HKD1_k127_6058370_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 375.0
HKD1_k127_6058370_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000005099 134.0
HKD1_k127_6058370_2 including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000007469 106.0
HKD1_k127_6058370_3 Protein of unknown function (DUF1232) - - - 0.0000000000000000002 94.0
HKD1_k127_6058370_4 - - - - 0.00000009396 63.0
HKD1_k127_6058370_5 Belongs to the 'phage' integrase family - - - 0.0008195 42.0
HKD1_k127_6064878_0 Elongation factor P K02356 - - 0.000000000000000000000000000000000000000000000000000000151 201.0
HKD1_k127_6065314_0 Putative diguanylate phosphodiesterase - - - 3.732e-222 729.0
HKD1_k127_6065314_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 359.0
HKD1_k127_6065314_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000001374 222.0
HKD1_k127_6065314_3 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000007658 160.0
HKD1_k127_6065314_4 arylamine N-acetyltransferase activity - - - 0.0000000000000000000000001249 119.0
HKD1_k127_6071586_0 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 372.0
HKD1_k127_6071586_1 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 312.0
HKD1_k127_6071586_2 Membrane - - - 0.00000000000000000000000000000000000000000001588 169.0
HKD1_k127_6071586_3 Rubredoxin - - - 0.00000000000000000000002066 105.0
HKD1_k127_6071586_4 - - - - 0.000000000000000000001859 103.0
HKD1_k127_6071586_5 Uncharacterized conserved protein (DUF2277) - - - 0.00000000008871 64.0
HKD1_k127_6071586_6 Antibiotic biosynthesis monooxygenase - - - 0.00001508 51.0
HKD1_k127_6077853_0 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008845 258.0
HKD1_k127_6077853_1 - - - - 0.000000000000002799 84.0
HKD1_k127_6077853_2 Domain of unknown function (DUF1877) - - - 0.0000001623 61.0
HKD1_k127_6080539_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000001236 90.0
HKD1_k127_6102374_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 491.0
HKD1_k127_6102374_1 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 391.0
HKD1_k127_6102374_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000002496 167.0
HKD1_k127_6102374_3 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 0.0000000000000000000000000002931 117.0
HKD1_k127_6102374_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000001997 116.0
HKD1_k127_6102374_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000112 104.0
HKD1_k127_6102374_6 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000007329 69.0
HKD1_k127_6104732_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 535.0
HKD1_k127_6104732_1 Tetratricopeptide repeat K20543 - - 0.00000000000000000000000000000000000000002795 173.0
HKD1_k127_6104732_2 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000002529 89.0
HKD1_k127_6110232_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 417.0
HKD1_k127_6110232_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 387.0
HKD1_k127_6110232_11 Tetratricopeptide repeat - - - 0.00004375 57.0
HKD1_k127_6110232_2 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000002925 217.0
HKD1_k127_6110232_3 COG0666 FOG Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000000005217 202.0
HKD1_k127_6110232_4 Serine Threonine protein kinase - - - 0.00000000000000000000000000000000000000000000004467 196.0
HKD1_k127_6110232_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000001191 174.0
HKD1_k127_6110232_6 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000001558 147.0
HKD1_k127_6110232_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000001366 129.0
HKD1_k127_6110232_8 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000002109 80.0
HKD1_k127_6110232_9 von Willebrand factor type A domain - - - 0.0000001072 59.0
HKD1_k127_6120139_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
HKD1_k127_6120139_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000001263 195.0
HKD1_k127_6120139_2 Tetratricopeptide repeat - - - 0.000005354 55.0
HKD1_k127_6120139_3 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.0000764 51.0
HKD1_k127_6132492_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 9.44e-202 659.0
HKD1_k127_6132492_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 393.0
HKD1_k127_6132492_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
HKD1_k127_6140989_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1313.0
HKD1_k127_6140989_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00316 - 1.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 591.0
HKD1_k127_6140989_2 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000000000000000000005676 179.0
HKD1_k127_6140989_3 Protein of unknown function (DUF861) - - - 0.0000000000000002426 84.0
HKD1_k127_6140989_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001226 74.0
HKD1_k127_6198880_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 421.0
HKD1_k127_6198880_1 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 383.0
HKD1_k127_6198880_2 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000002186 125.0
HKD1_k127_6198880_3 TonB dependent receptor K02014 - - 0.0001331 55.0
HKD1_k127_6198880_4 Receptor K16089 - - 0.0001757 54.0
HKD1_k127_6212399_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 343.0
HKD1_k127_6212399_1 WG containing repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001224 229.0
HKD1_k127_6212399_2 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000001721 214.0
HKD1_k127_6212399_3 - - - - 0.00000000000000000000000000000000000000004179 169.0
HKD1_k127_6212399_4 Calx-beta domain - - - 0.00000000000000000000003983 110.0
HKD1_k127_6224352_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 498.0
HKD1_k127_6224352_1 Peptidase family M28 - - - 0.00000000000000000000000000000001322 148.0
HKD1_k127_6224352_2 endonuclease I - - - 0.000000000000000000000000009934 129.0
HKD1_k127_6224352_3 Autotransporter beta-domain - - - 0.000000000000000002406 101.0
HKD1_k127_6224352_4 associated with various cellular activities - - - 0.00000000000007144 72.0
HKD1_k127_6224352_5 Belongs to the peptidase S8 family K13276,K17734 - - 0.00000000004789 77.0
HKD1_k127_6226505_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 431.0
HKD1_k127_6226505_1 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 297.0
HKD1_k127_6226505_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000211 112.0
HKD1_k127_6226829_0 Protein of unknown function (DUF779) K09959 - - 0.0000000000000000000000000000000000000000000000000000003231 196.0
HKD1_k127_6226829_1 belongs to the aldehyde dehydrogenase family K00138 - - 0.00000000000000000000000000000000000000000000000009302 177.0
HKD1_k127_6226829_2 FAD dependent oxidoreductase K19813 - 1.1.5.9 0.000001606 59.0
HKD1_k127_6226829_3 - - - - 0.000001624 58.0
HKD1_k127_624858_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 505.0
HKD1_k127_624858_1 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 428.0
HKD1_k127_624858_2 - - - - 0.00000000000000000000001088 104.0
HKD1_k127_6251545_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 446.0
HKD1_k127_6251545_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001735 271.0
HKD1_k127_6251545_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000009671 217.0
HKD1_k127_6251545_3 AI-2E family transporter - - - 0.00000000000000000000000000000002796 139.0
HKD1_k127_6251545_4 SnoaL-like domain - - - 0.00000000000000000000000004027 111.0
HKD1_k127_6251545_5 - - - - 0.00009613 48.0
HKD1_k127_6255429_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1125.0
HKD1_k127_6262324_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 537.0
HKD1_k127_6262324_1 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 362.0
HKD1_k127_6262324_2 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000001436 232.0
HKD1_k127_6262324_3 helix_turn_helix ASNC type K03718,K03719 - - 0.00004089 48.0
HKD1_k127_6280110_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003788 259.0
HKD1_k127_6280110_1 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000007636 121.0
HKD1_k127_6280110_2 Transglycosylase associated protein - - - 0.000000000000000000000000006911 111.0
HKD1_k127_6280110_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0001812 44.0
HKD1_k127_6283993_0 belongs to the aldehyde dehydrogenase family K00138 - - 0.00000000000000000000000000000000000000000000000000127 184.0
HKD1_k127_6283993_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000756 177.0
HKD1_k127_6283993_2 - - - - 0.0000000000000000000000000000000000001576 147.0
HKD1_k127_6283993_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000001484 143.0
HKD1_k127_6290686_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 9.604e-205 660.0
HKD1_k127_6290686_1 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000006596 87.0
HKD1_k127_6292628_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
HKD1_k127_6292628_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 332.0
HKD1_k127_6292628_2 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000006348 223.0
HKD1_k127_6296191_0 Aminotransferase class-III K03851,K15372 - 2.6.1.55,2.6.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 426.0
HKD1_k127_6296191_1 CarboxypepD_reg-like domain - - - 0.000000000000000000000000001797 131.0
HKD1_k127_6296191_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000004358 84.0
HKD1_k127_6296191_3 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000125 68.0
HKD1_k127_6299405_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 1.713e-317 977.0
HKD1_k127_6299405_1 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 600.0
HKD1_k127_6299405_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 377.0
HKD1_k127_6299405_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000002447 198.0
HKD1_k127_6299405_4 spore germination K03605 - - 0.000000000000000000000000000000000000000002936 162.0
HKD1_k127_6300097_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 456.0
HKD1_k127_6300097_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000002813 150.0
HKD1_k127_6300097_2 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000358 145.0
HKD1_k127_6300097_3 Domain of unknown function (DUF309) K09763 - - 0.0000000000000002509 86.0
HKD1_k127_6304784_0 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 333.0
HKD1_k127_6304784_1 general secretion pathway protein K02456 - - 0.0000000000000000000000000000000000003374 146.0
HKD1_k127_6304784_2 Type II secretion system protein G K02456 - - 0.000000000000000000000000000005415 128.0
HKD1_k127_6304784_3 general secretion pathway protein - - - 0.000000000000001227 83.0
HKD1_k127_6304784_4 - - - - 0.0000000004742 69.0
HKD1_k127_6304784_6 Pilus assembly protein K02662 - - 0.000004978 58.0
HKD1_k127_6304784_7 Pilus assembly protein K02663 - - 0.0000105 55.0
HKD1_k127_6306296_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1465.0
HKD1_k127_6306296_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 426.0
HKD1_k127_6306296_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.00000000000000000000000000000001949 128.0
HKD1_k127_6306296_3 Universal stress protein family - - - 0.00000000000000000000000002068 113.0
HKD1_k127_630851_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 598.0
HKD1_k127_630851_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 569.0
HKD1_k127_630851_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 332.0
HKD1_k127_630851_3 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 327.0
HKD1_k127_630851_4 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 285.0
HKD1_k127_630851_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001959 166.0
HKD1_k127_630851_6 YjbR - - - 0.0000000000000000000000000000000003524 135.0
HKD1_k127_630851_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000000000000187 131.0
HKD1_k127_630851_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000004427 108.0
HKD1_k127_630851_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000005633 107.0
HKD1_k127_6326639_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 527.0
HKD1_k127_6326639_1 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 503.0
HKD1_k127_6326639_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 421.0
HKD1_k127_6326639_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 305.0
HKD1_k127_6326639_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000004231 148.0
HKD1_k127_6326639_5 bacterial-type flagellum-dependent cell motility K02396,K13276 - - 0.00000000000002566 83.0
HKD1_k127_6330130_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.497e-223 706.0
HKD1_k127_6330130_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 342.0
HKD1_k127_6330130_2 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 309.0
HKD1_k127_6330130_3 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000003859 196.0
HKD1_k127_6330130_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000009429 186.0
HKD1_k127_6330130_5 PFAM Membrane protein of K08972 - - 0.0000000000000000009518 90.0
HKD1_k127_6330130_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000002203 85.0
HKD1_k127_6330130_7 Bacterial regulatory protein, Fis family K02584 - - 0.00000000005414 77.0
HKD1_k127_6330130_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07775 - - 0.000000004261 65.0
HKD1_k127_6344967_0 Heat shock 70 kDa protein K04043 - - 1.694e-300 932.0
HKD1_k127_6344967_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 363.0
HKD1_k127_6344967_2 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000000000325 151.0
HKD1_k127_6344967_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000003578 109.0
HKD1_k127_6355182_0 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000363 175.0
HKD1_k127_6355182_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000004291 138.0
HKD1_k127_6356907_0 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 355.0
HKD1_k127_6356907_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001638 262.0
HKD1_k127_6356907_2 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000707 229.0
HKD1_k127_6372676_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 522.0
HKD1_k127_6372676_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 451.0
HKD1_k127_6372676_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
HKD1_k127_6372676_3 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000001239 161.0
HKD1_k127_6372676_4 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.0000001587 55.0
HKD1_k127_6372676_5 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00002037 54.0
HKD1_k127_6376835_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 311.0
HKD1_k127_6376835_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000004366 216.0
HKD1_k127_6405703_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001276 286.0
HKD1_k127_6405703_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000009271 192.0
HKD1_k127_6405703_2 Lipase maturation factor - - - 0.0000000000000000000002603 98.0
HKD1_k127_6418751_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 333.0
HKD1_k127_6418751_1 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002931 254.0
HKD1_k127_6418751_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000004038 205.0
HKD1_k127_6418751_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006484 171.0
HKD1_k127_6418751_4 regulatory protein TetR - - - 0.000000000000000000000000000000000009809 143.0
HKD1_k127_6422077_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 484.0
HKD1_k127_6427403_0 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 334.0
HKD1_k127_6427403_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001197 216.0
HKD1_k127_6427403_2 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000002592 207.0
HKD1_k127_6427403_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000465 137.0
HKD1_k127_6427403_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000009018 70.0
HKD1_k127_6427403_5 HEPN domain - - - 0.0002545 51.0
HKD1_k127_6430975_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 - 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 490.0
HKD1_k127_6430975_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 326.0
HKD1_k127_6430975_2 UvrD-like helicase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 328.0
HKD1_k127_6430975_3 DinB superfamily - - - 0.00000000000785 66.0
HKD1_k127_6430975_4 PilZ domain - - - 0.0000551 49.0
HKD1_k127_6433888_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000184 258.0
HKD1_k127_6433888_1 PFAM SMP-30 Gluconolaconase K20952 - - 0.00000000000000000000000000000000000002362 161.0
HKD1_k127_6433888_2 Peptidase family C25 - - - 0.00000000000006568 85.0
HKD1_k127_6433888_3 HPr kinase - - - 0.00000009461 61.0
HKD1_k127_6433888_4 TIGRFAM conserved repeat domain - - - 0.0000001208 65.0
HKD1_k127_6433888_5 extracellular matrix structural constituent - - - 0.0000134 58.0
HKD1_k127_6456523_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005699 226.0
HKD1_k127_6456523_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000004916 214.0
HKD1_k127_6463347_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 430.0
HKD1_k127_6463347_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 370.0
HKD1_k127_6463347_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006486 242.0
HKD1_k127_6463347_3 - - - - 0.00000000000000002853 91.0
HKD1_k127_6475486_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 453.0
HKD1_k127_6475486_1 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000007249 222.0
HKD1_k127_6475486_2 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000004707 169.0
HKD1_k127_6475486_3 Thiol-disulfide oxidoreductase - - - 0.00000000000000000000000000000000000001856 151.0
HKD1_k127_6475486_4 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.0000000000000000000000000000004277 136.0
HKD1_k127_6475486_5 Aldehyde dehydrogenase K00128,K22445 - 1.2.1.3,1.2.99.10 0.000000000000000000000000000003145 121.0
HKD1_k127_6475486_6 cheY-homologous receiver domain - - - 0.00000000000000000000000006825 111.0
HKD1_k127_6479458_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 310.0
HKD1_k127_6479458_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000003401 178.0
HKD1_k127_6479458_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000004707 139.0
HKD1_k127_6479458_3 Vitamin K epoxide reductase family - - - 0.00000000000000000000000001955 123.0
HKD1_k127_6479458_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000002251 59.0
HKD1_k127_6479458_5 Histidine kinase - - - 0.000002983 57.0
HKD1_k127_6485603_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 486.0
HKD1_k127_6485603_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 384.0
HKD1_k127_6485603_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000003412 139.0
HKD1_k127_6485603_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000002035 119.0
HKD1_k127_6486773_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 535.0
HKD1_k127_6486773_1 Mur ligase middle domain protein K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 437.0
HKD1_k127_6486773_10 CBS domain-containing protein K03699 - - 0.000000000000000000000000000000000002466 143.0
HKD1_k127_6486773_11 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000001736 82.0
HKD1_k127_6486773_12 zinc-ribbon domain - - - 0.00000000001254 71.0
HKD1_k127_6486773_13 SprT-like family K07043 - - 0.0000003416 60.0
HKD1_k127_6486773_2 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 350.0
HKD1_k127_6486773_3 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 308.0
HKD1_k127_6486773_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009957 278.0
HKD1_k127_6486773_5 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000003518 235.0
HKD1_k127_6486773_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000003405 213.0
HKD1_k127_6486773_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000002188 199.0
HKD1_k127_6486773_8 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000008655 202.0
HKD1_k127_6486773_9 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000003415 198.0
HKD1_k127_6498611_0 Protein kinase domain K12132 - 2.7.11.1 3.883e-199 658.0
HKD1_k127_6498611_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
HKD1_k127_6498611_3 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000006113 200.0
HKD1_k127_6498611_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000159 162.0
HKD1_k127_6498611_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000001542 107.0
HKD1_k127_6498611_6 PFAM EamA-like transporter family - - - 0.0000000000000001398 93.0
HKD1_k127_6498611_7 - - - - 0.000000000002474 77.0
HKD1_k127_6498611_8 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000002414 62.0
HKD1_k127_6502704_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 553.0
HKD1_k127_6502704_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 362.0
HKD1_k127_6502704_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
HKD1_k127_6502704_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000002347 195.0
HKD1_k127_6502704_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000001143 154.0
HKD1_k127_6513131_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 496.0
HKD1_k127_6513131_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 470.0
HKD1_k127_6513131_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD1_k127_6513131_3 nuclease activity K07460 - - 0.00000000000000000000008478 102.0
HKD1_k127_6513131_4 Glycosyl transferases group 1 - - - 0.0000000000000000000007445 97.0
HKD1_k127_6517993_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002424 286.0
HKD1_k127_6517993_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000002357 243.0
HKD1_k127_6517993_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001202 117.0
HKD1_k127_6522814_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 389.0
HKD1_k127_6522814_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 364.0
HKD1_k127_6522814_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 334.0
HKD1_k127_6532670_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000002679 184.0
HKD1_k127_6536751_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 0.0 1050.0
HKD1_k127_6536751_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 580.0
HKD1_k127_6536751_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 530.0
HKD1_k127_6536751_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 508.0
HKD1_k127_6536751_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 454.0
HKD1_k127_6536751_5 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 343.0
HKD1_k127_6536751_6 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 325.0
HKD1_k127_6536751_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000002131 96.0
HKD1_k127_6536751_8 - - - - 0.00000000238 63.0
HKD1_k127_6541292_0 Flotillin K07192 - - 1.574e-221 695.0
HKD1_k127_6541292_1 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
HKD1_k127_6547360_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 414.0
HKD1_k127_6547360_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 235.0
HKD1_k127_6547360_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000004201 192.0
HKD1_k127_6547360_3 - - - - 0.000000000000000000000000000000000000000000000000006024 189.0
HKD1_k127_6547360_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000004278 99.0
HKD1_k127_6547360_5 (Hpt) domain - - - 0.0000000000001566 77.0
HKD1_k127_6553194_0 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000002192 248.0
HKD1_k127_6553194_1 - K12065 - - 0.00000000000000000000000000000000000000000000000000203 198.0
HKD1_k127_6553194_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000005174 171.0
HKD1_k127_6553194_3 hopanoid biosynthesis associated protein HpnK - - - 0.0000000000000000000000000000000000003144 149.0
HKD1_k127_6555752_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 452.0
HKD1_k127_6555752_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 433.0
HKD1_k127_6555752_2 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000003227 181.0
HKD1_k127_6555752_3 ACT domain K03567 - - 0.000000000000000000000000000000008353 136.0
HKD1_k127_6570488_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 582.0
HKD1_k127_6570488_1 - K19693 - - 0.0000000000000000000000000008393 117.0
HKD1_k127_6570488_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000001981 104.0
HKD1_k127_6591386_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
HKD1_k127_6591386_1 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000003868 255.0
HKD1_k127_6591386_2 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000000000004059 165.0
HKD1_k127_6591386_3 protein ubiquitination K15502,K15503,K20032,K21440 - 2.3.1.225 0.000000000000000001716 96.0
HKD1_k127_6631859_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 337.0
HKD1_k127_6631859_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
HKD1_k127_6631859_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 316.0
HKD1_k127_6631859_3 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002445 266.0
HKD1_k127_6631859_4 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000003412 231.0
HKD1_k127_6631859_5 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000001833 201.0
HKD1_k127_6631859_6 dephospho-CoA kinase activity - - - 0.000000000000000000000000000000000006814 149.0
HKD1_k127_6631859_7 bacterial-type flagellum-dependent cell motility K20951,K20952 - - 0.000000000000000000000000000001314 135.0
HKD1_k127_6640002_0 Belongs to the thiolase family K07508 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 447.0
HKD1_k127_6640002_1 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 288.0
HKD1_k127_6640002_2 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000007037 212.0
HKD1_k127_6640002_3 Peptidase C13 family - - - 0.00007541 53.0
HKD1_k127_6640613_0 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 326.0
HKD1_k127_6640613_1 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000003035 166.0
HKD1_k127_6649678_0 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 336.0
HKD1_k127_6649678_1 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 305.0
HKD1_k127_6649678_2 Protease prsW family - - - 0.000000001629 67.0
HKD1_k127_6649678_3 (FHA) domain - - - 0.00000001773 64.0
HKD1_k127_6656688_0 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 612.0
HKD1_k127_6656688_1 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000017 204.0
HKD1_k127_6656688_2 methyltransferase - - - 0.000000000000000000000000000000000001545 150.0
HKD1_k127_6656688_3 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000005095 103.0
HKD1_k127_6656688_4 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000001574 60.0
HKD1_k127_6658096_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HKD1_k127_6658096_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000172 239.0
HKD1_k127_6658096_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000003655 188.0
HKD1_k127_6658096_3 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000001209 78.0
HKD1_k127_6667535_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.097e-292 906.0
HKD1_k127_6667535_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 500.0
HKD1_k127_6667535_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000002185 220.0
HKD1_k127_6667535_3 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000000000000000000002527 243.0
HKD1_k127_6667535_4 amine oxidase K00276 - 1.4.3.21 0.0000000000000000000000000000000000000000000000002033 190.0
HKD1_k127_6667535_5 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000005152 168.0
HKD1_k127_6667535_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000003952 148.0
HKD1_k127_6667535_7 PspC domain protein - - - 0.000000000000000000009283 93.0
HKD1_k127_6667535_8 Belongs to the peptidase S8 family - - - 0.000000000000007712 90.0
HKD1_k127_6693983_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 293.0
HKD1_k127_6693983_1 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000003421 193.0
HKD1_k127_6693983_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001263 192.0
HKD1_k127_6693983_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000001749 176.0
HKD1_k127_6693983_4 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000001169 131.0
HKD1_k127_6693983_5 Putative regulatory protein - - - 0.000000003205 60.0
HKD1_k127_6696139_0 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 497.0
HKD1_k127_6696139_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 365.0
HKD1_k127_6696139_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000002385 247.0
HKD1_k127_6696139_3 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000004774 234.0
HKD1_k127_6696139_4 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000002614 165.0
HKD1_k127_6696139_5 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000222 105.0
HKD1_k127_672860_0 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 544.0
HKD1_k127_672860_1 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000000000000000001961 194.0
HKD1_k127_672860_2 Spermidine putrescine-binding periplasmic protein K11069 - - 0.000000000000000000000000000000000172 135.0
HKD1_k127_6740149_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 466.0
HKD1_k127_6740149_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
HKD1_k127_6740149_2 Dehydrogenase reductase SDR family member K11169,K16585 - - 0.0000000000002331 74.0
HKD1_k127_674050_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 310.0
HKD1_k127_674050_1 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002991 283.0
HKD1_k127_674050_2 Zn_pept - - - 0.000000000000000000000000000000000000000000000001018 199.0
HKD1_k127_674050_3 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000006708 176.0
HKD1_k127_674050_4 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000002645 135.0
HKD1_k127_674050_5 Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties K19882 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0008150,GO:0009505,GO:0009506,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0030054,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0052689,GO:0052793,GO:0055044,GO:0071554,GO:0071555,GO:0071840,GO:0071944 3.1.1.98 0.000000000000000001071 93.0
HKD1_k127_674050_6 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000001759 98.0
HKD1_k127_6744161_0 (ABC) transporter K06147,K06148 - - 7.959e-210 681.0
HKD1_k127_6744161_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 371.0
HKD1_k127_6744161_2 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004825 294.0
HKD1_k127_6744161_3 Aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000001002 240.0
HKD1_k127_6744161_4 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000008832 207.0
HKD1_k127_6744161_5 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000002278 207.0
HKD1_k127_6744161_6 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.000000000000000000000002577 109.0
HKD1_k127_6744161_7 - - - - 0.0000000000000000004672 91.0
HKD1_k127_6744161_8 Hpt domain - - - 0.00000000127 63.0
HKD1_k127_6745386_0 xaa-Pro dipeptidase K14213 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 403.0
HKD1_k127_6745386_1 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 352.0
HKD1_k127_6756077_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001845 259.0
HKD1_k127_6756077_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000001698 183.0
HKD1_k127_6756077_2 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal - - - 0.000000000000000000000000000000000000000000000002613 175.0
HKD1_k127_6756077_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000008147 181.0
HKD1_k127_6758625_0 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 527.0
HKD1_k127_6767605_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 438.0
HKD1_k127_6767605_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000003524 113.0
HKD1_k127_6767605_2 Methyltransferase type 11 K00574 - 2.1.1.79 0.00000000000002497 85.0
HKD1_k127_6771702_0 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
HKD1_k127_6771702_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003751 269.0
HKD1_k127_6771702_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000006241 233.0
HKD1_k127_6771702_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000005787 86.0
HKD1_k127_6771702_4 BON domain - - - 0.000000000007485 75.0
HKD1_k127_6772477_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 484.0
HKD1_k127_6772477_1 LuxR family transcriptional regulator K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000001687 240.0
HKD1_k127_6772477_2 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000004385 215.0
HKD1_k127_6772477_3 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000001397 184.0
HKD1_k127_6772477_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000008465 153.0
HKD1_k127_6772477_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.0000000000000000000000000000000000001681 158.0
HKD1_k127_6777308_0 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 339.0
HKD1_k127_6777308_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 258.0
HKD1_k127_6777308_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000009506 226.0
HKD1_k127_6777308_3 ABC-2 family transporter protein K01992,K09696 - - 0.000000000000000000000000000000000000000000000000000000000002411 222.0
HKD1_k127_6777308_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000005937 196.0
HKD1_k127_6777308_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000002335 186.0
HKD1_k127_6777308_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001058 165.0
HKD1_k127_6787503_0 3-oxoacid CoA-transferase, a subunit K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 352.0
HKD1_k127_6787503_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 316.0
HKD1_k127_6787503_2 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 290.0
HKD1_k127_6787503_3 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 293.0
HKD1_k127_6787503_4 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.000000000000000000000000000000000001633 142.0
HKD1_k127_6791609_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 310.0
HKD1_k127_6791609_1 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005501 287.0
HKD1_k127_6791609_2 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000567 235.0
HKD1_k127_6791609_3 - - - - 0.00000000003129 70.0
HKD1_k127_68136_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000006447 145.0
HKD1_k127_68136_1 COGs COG3603 conserved K09707 - - 0.00000000000000000000000000000000008727 136.0
HKD1_k127_6816774_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 550.0
HKD1_k127_6816774_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
HKD1_k127_6816774_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000009659 209.0
HKD1_k127_6816774_3 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000002286 220.0
HKD1_k127_6821291_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 459.0
HKD1_k127_6821291_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 310.0
HKD1_k127_6821291_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 285.0
HKD1_k127_6821291_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002439 264.0
HKD1_k127_6821291_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.000000000000000000000000000000000000000000001451 172.0
HKD1_k127_6821291_5 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000004641 72.0
HKD1_k127_684511_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
HKD1_k127_684511_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000002543 107.0
HKD1_k127_684511_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000004263 100.0
HKD1_k127_6849146_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 423.0
HKD1_k127_6849146_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000001555 217.0
HKD1_k127_6864594_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 602.0
HKD1_k127_6864594_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000005723 161.0
HKD1_k127_6864594_2 Domain of unknown function (DUF4440) - - - 0.0000000000000004062 80.0
HKD1_k127_6877849_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 286.0
HKD1_k127_6877849_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000001321 100.0
HKD1_k127_6877849_2 peptidase dimerisation domain protein K13049 - - 0.0006183 48.0
HKD1_k127_6895553_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 461.0
HKD1_k127_6895553_1 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 421.0
HKD1_k127_6895553_2 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 388.0
HKD1_k127_6895553_3 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 351.0
HKD1_k127_6895553_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002485 237.0
HKD1_k127_6895553_5 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000000000001269 203.0
HKD1_k127_6895553_6 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000009714 153.0
HKD1_k127_6895553_7 response to oxidative stress K04063 - - 0.0000000000000000000000000000000000842 138.0
HKD1_k127_6895553_8 CAAX protease self-immunity - - - 0.000000000000000000000000003098 120.0
HKD1_k127_6897002_0 peptidase M13 K07386 - - 8.871e-242 766.0
HKD1_k127_6897002_1 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 382.0
HKD1_k127_6898864_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.455e-216 680.0
HKD1_k127_6898864_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000006018 247.0
HKD1_k127_6900202_0 Belongs to the aldehyde dehydrogenase family K22187 - - 1.15e-208 659.0
HKD1_k127_6900202_1 Polymer-forming cytoskeletal - - - 0.0000000000000000002133 94.0
HKD1_k127_6917150_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.024e-202 642.0
HKD1_k127_6917150_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 391.0
HKD1_k127_6917150_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000002565 228.0
HKD1_k127_6917150_4 Domain of unknown function (DUF4203) - - - 0.0000000000000000000000001747 112.0
HKD1_k127_6917150_5 Domain of Unknown Function (DUF1080) - - - 0.0000000008608 71.0
HKD1_k127_6923857_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 475.0
HKD1_k127_6923857_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 448.0
HKD1_k127_6923857_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003151 286.0
HKD1_k127_6923857_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000004492 160.0
HKD1_k127_6923857_4 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000002233 154.0
HKD1_k127_6923857_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000008242 116.0
HKD1_k127_6923857_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000005773 100.0
HKD1_k127_6928917_0 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
HKD1_k127_6928917_1 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 354.0
HKD1_k127_6931764_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 448.0
HKD1_k127_6931764_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000009475 253.0
HKD1_k127_6931764_10 Universal stress protein family - - - 0.0000000000001183 81.0
HKD1_k127_6931764_11 universal stress protein - - - 0.0000000000006482 79.0
HKD1_k127_6931764_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000638 205.0
HKD1_k127_6931764_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000004697 153.0
HKD1_k127_6931764_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000005168 125.0
HKD1_k127_6931764_5 Belongs to the beta-eliminating lyase family K01667 - 4.1.99.1 0.00000000000000000000002689 103.0
HKD1_k127_6931764_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000001024 93.0
HKD1_k127_6931764_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000001943 89.0
HKD1_k127_6931764_9 Cytochrome c7 and related cytochrome c - - - 0.00000000000009223 78.0
HKD1_k127_6942446_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.803e-203 653.0
HKD1_k127_6942446_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 308.0
HKD1_k127_6942446_10 - - - - 0.00009355 52.0
HKD1_k127_6942446_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007885 285.0
HKD1_k127_6942446_3 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000287 175.0
HKD1_k127_6942446_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000004897 154.0
HKD1_k127_6942446_5 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000007283 140.0
HKD1_k127_6942446_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000007246 130.0
HKD1_k127_6942446_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000003578 117.0
HKD1_k127_6942446_8 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000001967 92.0
HKD1_k127_6942446_9 TonB C terminal K03646,K03832 - - 0.000000009419 67.0
HKD1_k127_6976247_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 500.0
HKD1_k127_6976247_1 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000007374 117.0
HKD1_k127_699428_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 461.0
HKD1_k127_699428_1 - - - - 0.000000000000000000000000000000000000000001903 159.0
HKD1_k127_699428_2 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000004621 115.0
HKD1_k127_699428_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001187 58.0
HKD1_k127_7002274_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 332.0
HKD1_k127_7002274_1 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000004628 225.0
HKD1_k127_700471_0 Chemotaxis protein CheC K03410 - - 0.0000000000000000000000000000000000000000000000000000000004057 210.0
HKD1_k127_700471_1 P2 response regulator binding domain protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000009396 162.0
HKD1_k127_700471_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000001396 126.0
HKD1_k127_700471_3 Patatin-like phospholipase K07001,K15477,K16638 - - 0.00000000000000000000001032 111.0
HKD1_k127_700471_4 antisigma factor binding K04749 - - 0.0000009203 57.0
HKD1_k127_7012777_0 Glycoside hydrolase family 44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 391.0
HKD1_k127_7012777_1 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000000000000000000000000000000000000002053 226.0
HKD1_k127_7012777_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
HKD1_k127_7012777_3 Transcription termination factor nusG - - - 0.00000000000000000000000000000000000002257 150.0
HKD1_k127_7019428_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1170.0
HKD1_k127_7019428_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 482.0
HKD1_k127_7019428_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 332.0
HKD1_k127_7019428_3 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 329.0
HKD1_k127_7019428_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 314.0
HKD1_k127_7019428_5 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 310.0
HKD1_k127_7019428_6 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 300.0
HKD1_k127_7019428_7 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001461 239.0
HKD1_k127_7030712_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 1.633e-215 677.0
HKD1_k127_7030712_1 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 498.0
HKD1_k127_7030712_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 369.0
HKD1_k127_7030712_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
HKD1_k127_7030712_4 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000000000000000000000001317 144.0
HKD1_k127_7030712_5 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000007091 134.0
HKD1_k127_7030712_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000006375 113.0
HKD1_k127_7030712_7 methyltransferase activity - - - 0.00000000000000395 83.0
HKD1_k127_7030758_0 PFAM Protein kinase K03413 - - 0.000000000000000000000000000000000000000000000000001588 208.0
HKD1_k127_7030758_1 Protein of unknown function (DUF1349) - - - 0.0000000000000000000000000000000000003843 158.0
HKD1_k127_7030758_2 chaperone-mediated protein folding - - - 0.00000003059 64.0
HKD1_k127_7032968_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HKD1_k127_7032968_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000001743 218.0
HKD1_k127_7032968_2 Thioredoxin domain - - - 0.000000000000000000000000006285 115.0
HKD1_k127_7032968_3 - - - - 0.000000000000000001436 92.0
HKD1_k127_7032968_4 Glutaredoxin-like domain protein - - - 0.0000000000000004003 79.0
HKD1_k127_7034650_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 435.0
HKD1_k127_7034650_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 306.0
HKD1_k127_7034650_2 bacterial-type flagellum-dependent cell motility K20951,K20952 - - 0.0000000000000000000000000000000002272 146.0
HKD1_k127_7034650_4 Subtilase family K08651 - 3.4.21.66 0.0000000006369 72.0
HKD1_k127_7034650_5 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000001971 57.0
HKD1_k127_7054439_0 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 302.0
HKD1_k127_7054439_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 261.0
HKD1_k127_7054439_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004245 276.0
HKD1_k127_7054439_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001038 269.0
HKD1_k127_7054439_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000004109 245.0
HKD1_k127_7054439_5 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000002795 139.0
HKD1_k127_705535_0 Fumarase C C-terminus - - - 1.424e-229 719.0
HKD1_k127_705535_1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 418.0
HKD1_k127_705535_2 Anaerobic c4-dicarboxylate membrane transporter K07791,K07792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 314.0
HKD1_k127_705535_3 malic enzyme K00029 - 1.1.1.40 0.000000000000000000000000000000000001724 141.0
HKD1_k127_7057002_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.805e-195 616.0
HKD1_k127_7057002_1 Enoyl-CoA hydratase isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 567.0
HKD1_k127_7057002_2 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 443.0
HKD1_k127_7057002_3 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 404.0
HKD1_k127_7057002_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000001192 127.0
HKD1_k127_7057002_5 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.000000000000003727 79.0
HKD1_k127_7073757_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 388.0
HKD1_k127_7073757_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 370.0
HKD1_k127_7073757_2 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 320.0
HKD1_k127_7073757_3 domain protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000194 285.0
HKD1_k127_7073757_4 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000001315 141.0
HKD1_k127_7073757_5 Esterase PHB depolymerase - - - 0.00000000000000000548 99.0
HKD1_k127_7091197_0 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 554.0
HKD1_k127_7091197_1 Bile acid sodium K03453 - - 0.0000000000000000000000000005525 127.0
HKD1_k127_7091197_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000002103 112.0
HKD1_k127_7091197_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000004673 49.0
HKD1_k127_7093875_0 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000001733 216.0
HKD1_k127_7093875_1 - - - - 0.000000000000000000000000000000000000000002366 159.0
HKD1_k127_7093875_2 NUDIX domain - - - 0.00000000000000002659 88.0
HKD1_k127_7093875_3 Transfers the fatty acyl group on membrane lipoproteins - - - 0.000000000002942 76.0
HKD1_k127_7149158_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 387.0
HKD1_k127_7149158_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007318 261.0
HKD1_k127_7149158_2 NHL repeat - - - 0.000000000000000000001173 112.0
HKD1_k127_7149158_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000002816 86.0
HKD1_k127_7149158_4 Belongs to the UPF0296 family K09777 - - 0.0000000000001493 74.0
HKD1_k127_714946_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 499.0
HKD1_k127_714946_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 453.0
HKD1_k127_714946_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 308.0
HKD1_k127_716854_0 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 369.0
HKD1_k127_716854_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000005456 188.0
HKD1_k127_716854_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000007899 141.0
HKD1_k127_716854_3 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000001498 141.0
HKD1_k127_716854_4 lipoprotein localization to outer membrane - - - 0.000000000000000000002553 99.0
HKD1_k127_718136_0 FtsX-like permease family K02004 - - 1.953e-232 756.0
HKD1_k127_718136_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 345.0
HKD1_k127_718136_2 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 346.0
HKD1_k127_718136_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 307.0
HKD1_k127_718136_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000004171 188.0
HKD1_k127_718136_5 DNA-binding transcription factor activity - - - 0.0000000000000005119 90.0
HKD1_k127_7194250_0 4Fe-4S binding domain - - - 4.694e-257 814.0
HKD1_k127_7194250_1 nuclease activity - - - 0.00000000000000000000000000000000000001047 148.0
HKD1_k127_7203599_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1089.0
HKD1_k127_7203599_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 452.0
HKD1_k127_7203599_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 391.0
HKD1_k127_7203599_3 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000001693 122.0
HKD1_k127_7203599_4 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000001963 76.0
HKD1_k127_7220365_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000619 145.0
HKD1_k127_7220365_1 Glycosyl transferase, group K20444 - - 0.00000000000000000000000006248 124.0
HKD1_k127_7229431_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1100.0
HKD1_k127_7229431_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 2.798e-317 993.0
HKD1_k127_7229431_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 393.0
HKD1_k127_7229431_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
HKD1_k127_7229431_4 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000001545 227.0
HKD1_k127_7229431_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000344 171.0
HKD1_k127_7232257_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 307.0
HKD1_k127_7232257_1 - - - - 0.000000000000000000000000000000000000002482 149.0
HKD1_k127_7232257_2 NUDIX domain - - - 0.000000000000000000000000000000000003175 144.0
HKD1_k127_7232257_3 - - - - 0.0000000000000000000000000000000001229 144.0
HKD1_k127_7240620_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 436.0
HKD1_k127_7240620_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 348.0
HKD1_k127_7240620_2 translation release factor activity - - - 0.0000000000000000000000000000000000000000001329 162.0
HKD1_k127_7246202_0 Protein of unknown function (DUF3604) - - - 0.0 1084.0
HKD1_k127_7246202_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 327.0
HKD1_k127_7246202_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000003166 209.0
HKD1_k127_7246202_3 DJ-1/PfpI family - - - 0.000000000000000000000000000000001942 143.0
HKD1_k127_7246202_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000136 90.0
HKD1_k127_7246202_5 Serine aminopeptidase, S33 K06889 - - 0.00000000001692 76.0
HKD1_k127_7256831_0 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 574.0
HKD1_k127_7256831_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
HKD1_k127_7256831_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000006804 229.0
HKD1_k127_7256831_3 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000001005 148.0
HKD1_k127_7256831_4 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000002156 141.0
HKD1_k127_7256831_5 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000000000002114 106.0
HKD1_k127_7264674_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 349.0
HKD1_k127_7264674_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000004868 151.0
HKD1_k127_7264674_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000006128 113.0
HKD1_k127_7264674_3 Aspartyl protease - - - 0.000000000000000004671 98.0
HKD1_k127_7264674_4 Fatty acid hydroxylase - - - 0.000000000000003615 84.0
HKD1_k127_7264674_5 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000001039 75.0
HKD1_k127_7264674_6 Acyl-transferase K00655 - 2.3.1.51 0.000000003017 67.0
HKD1_k127_7271850_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 535.0
HKD1_k127_7271850_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 396.0
HKD1_k127_7271850_2 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000000000005594 186.0
HKD1_k127_7271850_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000004586 155.0
HKD1_k127_7271850_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000006104 74.0
HKD1_k127_7271850_5 Domain of unknown function (DUF3859) - - - 0.00000000001943 71.0
HKD1_k127_7276104_0 ABC-2 family transporter protein - - - 0.0000005306 62.0
HKD1_k127_7276104_1 ATPases associated with a variety of cellular activities K01990 - - 0.0002799 46.0
HKD1_k127_7297059_0 M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 469.0
HKD1_k127_7297059_1 Abc transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 309.0
HKD1_k127_7297059_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000283 147.0
HKD1_k127_7304202_0 DEAD DEAH box K03724 - - 3.118e-272 861.0
HKD1_k127_7304202_1 DEAD DEAH box K03724 - - 4.866e-265 829.0
HKD1_k127_7304202_3 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
HKD1_k127_7304202_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000334 231.0
HKD1_k127_7304202_5 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000006662 130.0
HKD1_k127_7304202_6 Transglycosylase SLT domain - - - 0.00000000000000000000000000000506 128.0
HKD1_k127_7304202_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000288 97.0
HKD1_k127_7304737_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 351.0
HKD1_k127_7304737_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 316.0
HKD1_k127_7304737_2 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 305.0
HKD1_k127_7304737_3 DinB superfamily K07552 - - 0.000000000000000000000000000000000000002711 153.0
HKD1_k127_7317797_0 IgA Peptidase M64 - - - 1.829e-208 656.0
HKD1_k127_7317797_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 303.0
HKD1_k127_7317797_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009104 289.0
HKD1_k127_7317797_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000003534 195.0
HKD1_k127_7317797_4 DinB family - - - 0.0000000000000000000000000000000000000000000596 166.0
HKD1_k127_7317797_5 Peptidase family M28 - - - 0.0009281 50.0
HKD1_k127_7320616_0 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000003124 112.0
HKD1_k127_7320616_1 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001113 100.0
HKD1_k127_7320616_2 Protein of unknown function (DUF2752) - - - 0.0000000000000007524 83.0
HKD1_k127_7320616_3 Haemolytic K08998 - - 0.00000000000000176 80.0
HKD1_k127_7320616_4 TM2 domain - - - 0.00004392 51.0
HKD1_k127_7343149_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 9.695e-226 706.0
HKD1_k127_7343149_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 399.0
HKD1_k127_7343149_2 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000002989 207.0
HKD1_k127_7343149_3 SNARE associated Golgi protein - - - 0.0000000000000000000006443 103.0
HKD1_k127_7356148_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
HKD1_k127_7356148_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 317.0
HKD1_k127_7356148_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000007763 205.0
HKD1_k127_7356148_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000002361 202.0
HKD1_k127_7356148_4 - - - - 0.00000000000000000000000000000000004934 142.0
HKD1_k127_7364332_0 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
HKD1_k127_7364332_1 - - - - 0.000000000000000000000000000000000004735 141.0
HKD1_k127_7364332_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003659 138.0
HKD1_k127_7368122_0 O-methyltransferase - - - 4.46e-253 804.0
HKD1_k127_7368122_1 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 488.0
HKD1_k127_7368122_2 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000001554 195.0
HKD1_k127_7377413_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.205e-311 974.0
HKD1_k127_7377413_1 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
HKD1_k127_7377413_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000001059 162.0
HKD1_k127_7377413_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000000000000000002821 134.0
HKD1_k127_7377413_4 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000332 130.0
HKD1_k127_7377413_5 - - - - 0.0000000000000007035 78.0
HKD1_k127_7377413_6 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000279 61.0
HKD1_k127_7382613_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 455.0
HKD1_k127_7382613_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 430.0
HKD1_k127_7382613_2 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 369.0
HKD1_k127_7382613_3 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
HKD1_k127_7382613_4 histone acetyltransferase binding - - - 0.000000000000000000000000000000000000000000000000000000000005729 225.0
HKD1_k127_7382613_5 - - - - 0.00000000000000000004049 99.0
HKD1_k127_7409394_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 581.0
HKD1_k127_7409394_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000001253 232.0
HKD1_k127_7409394_2 - - - - 0.000000000000000000000000002136 126.0
HKD1_k127_7409394_3 Helix-turn-helix domain K15539 - - 0.0000000000002058 75.0
HKD1_k127_7409394_4 - - - - 0.0000000000002803 79.0
HKD1_k127_7409394_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000001311 63.0
HKD1_k127_7413099_0 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000009227 188.0
HKD1_k127_7413099_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000001036 134.0
HKD1_k127_7413099_2 - - - - 0.000005234 56.0
HKD1_k127_7417467_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000001508 239.0
HKD1_k127_7417467_1 Mitochondrial biogenesis AIM24 - - - 0.000000000003861 79.0
HKD1_k127_7432302_0 Glycogen debranching enzyme - - - 0.0 1555.0
HKD1_k127_7432302_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000005908 64.0
HKD1_k127_7440307_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.232e-272 845.0
HKD1_k127_7440307_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 587.0
HKD1_k127_7440307_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 494.0
HKD1_k127_7440307_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 424.0
HKD1_k127_7440307_4 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 327.0
HKD1_k127_7440307_5 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004165 287.0
HKD1_k127_7440307_6 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000001825 212.0
HKD1_k127_7440307_7 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000009229 183.0
HKD1_k127_7440307_8 TOPRIM - - - 0.00000000007568 68.0
HKD1_k127_7466054_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 531.0
HKD1_k127_7466054_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 540.0
HKD1_k127_7466054_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 385.0
HKD1_k127_7466054_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000004449 177.0
HKD1_k127_7469592_0 Domain in cystathionine beta-synthase and other proteins. - - - 2.821e-238 754.0
HKD1_k127_7469592_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 504.0
HKD1_k127_7469592_2 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
HKD1_k127_7469592_3 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 367.0
HKD1_k127_7469592_4 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005173 276.0
HKD1_k127_7469592_5 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000183 240.0
HKD1_k127_7469592_6 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000003791 123.0
HKD1_k127_7469592_7 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000004283 110.0
HKD1_k127_7469592_8 Parallel beta-helix repeats - - - 0.0000000000000000004206 103.0
HKD1_k127_7469592_9 dioxygenase activity - - - 0.0000000000000000004575 98.0
HKD1_k127_7470958_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 380.0
HKD1_k127_7470958_1 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
HKD1_k127_7470958_2 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000001981 191.0
HKD1_k127_7470958_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000002505 174.0
HKD1_k127_7470958_4 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000002293 127.0
HKD1_k127_7470958_5 SnoaL-like domain - - - 0.00000000003515 69.0
HKD1_k127_7470958_6 Receptor K16089,K19611 - - 0.0001392 50.0
HKD1_k127_7479497_0 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 530.0
HKD1_k127_7479497_1 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 362.0
HKD1_k127_7479497_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 307.0
HKD1_k127_7479497_3 - - - - 0.0004857 43.0
HKD1_k127_7499720_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 381.0
HKD1_k127_7499720_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000002574 220.0
HKD1_k127_7499720_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000007617 197.0
HKD1_k127_7499720_3 TIGR00255 family - - - 0.000000000000000000000000000000000000007661 151.0
HKD1_k127_7499720_4 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000001647 112.0
HKD1_k127_7499720_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000006819 90.0
HKD1_k127_7499720_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000001469 53.0
HKD1_k127_7499814_0 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 440.0
HKD1_k127_7499814_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000006091 253.0
HKD1_k127_7499814_2 - - - - 0.00000000000000000000000000000000000000000000000000004246 201.0
HKD1_k127_7499814_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000008545 110.0
HKD1_k127_7499814_4 DNA RNA non-specific endonuclease - - - 0.0000000000000008908 85.0
HKD1_k127_7513303_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 339.0
HKD1_k127_7513303_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 334.0
HKD1_k127_7513303_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000005885 107.0
HKD1_k127_7520985_0 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000008589 272.0
HKD1_k127_7520985_1 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005302 265.0
HKD1_k127_7520985_2 Winged helix DNA-binding domain - - - 0.0000000000000000000000432 104.0
HKD1_k127_7540325_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 308.0
HKD1_k127_7540325_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000001095 228.0
HKD1_k127_7540325_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000001016 154.0
HKD1_k127_7540686_0 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003159 284.0
HKD1_k127_7540686_1 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 258.0
HKD1_k127_7540686_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000001068 240.0
HKD1_k127_7540686_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000001264 80.0
HKD1_k127_7543824_0 SMART ATPase, AAA type, core K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 304.0
HKD1_k127_7543824_1 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 286.0
HKD1_k127_7543824_2 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 258.0
HKD1_k127_7543824_3 Cytochrome c7 and related cytochrome c - - - 0.00005495 48.0
HKD1_k127_7560588_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 314.0
HKD1_k127_7560588_1 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000002329 140.0
HKD1_k127_7571979_0 PFAM NHL repeat containing protein - - - 3.459e-286 913.0
HKD1_k127_7571979_1 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000379 188.0
HKD1_k127_7580937_0 - - - - 4.101e-202 653.0
HKD1_k127_7580937_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 479.0
HKD1_k127_7580937_2 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000000000000000000000000000005855 203.0
HKD1_k127_7580937_3 C-terminal binding-module, SLH-like, of glucodextranase K01178 - 3.2.1.3 0.000000000000000000000000000000003613 129.0
HKD1_k127_7596306_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002371 293.0
HKD1_k127_7596306_1 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.00000000000000000000000000000000000000000006207 166.0
HKD1_k127_7613068_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 337.0
HKD1_k127_7613068_1 MoaE protein K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000001135 175.0
HKD1_k127_7624114_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 381.0
HKD1_k127_7624114_1 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 384.0
HKD1_k127_7624114_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 282.0
HKD1_k127_7624114_3 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
HKD1_k127_7624114_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000007061 188.0
HKD1_k127_7624114_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000001698 128.0
HKD1_k127_7624114_6 GatB domain - - - 0.000000003929 57.0
HKD1_k127_7624114_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000001723 58.0
HKD1_k127_7635822_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000007641 208.0
HKD1_k127_7635822_1 protein histidine kinase activity K03271 - 5.3.1.28 0.000000000000000000000000001079 122.0
HKD1_k127_7635822_2 Domain of unknown function (DUF4190) - - - 0.00000002173 61.0
HKD1_k127_7637317_0 cystathionine gamma-synthase activity K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 499.0
HKD1_k127_7637317_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 384.0
HKD1_k127_7637317_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 373.0
HKD1_k127_7637317_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000002364 163.0
HKD1_k127_7638450_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 387.0
HKD1_k127_7638450_1 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000001703 131.0
HKD1_k127_7638450_2 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000002097 75.0
HKD1_k127_7658332_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1370.0
HKD1_k127_7658332_1 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000001614 94.0
HKD1_k127_7683687_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 413.0
HKD1_k127_7683687_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
HKD1_k127_7683687_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004449 284.0
HKD1_k127_7683687_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
HKD1_k127_7687433_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 392.0
HKD1_k127_7687433_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000269 297.0
HKD1_k127_7687433_10 - - - - 0.00000000000005491 85.0
HKD1_k127_7687433_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001902 277.0
HKD1_k127_7687433_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000004681 151.0
HKD1_k127_7687433_4 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000003015 138.0
HKD1_k127_7687433_5 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000003122 132.0
HKD1_k127_7687433_6 Transcriptional regulator - - - 0.0000000000000000000000000001711 119.0
HKD1_k127_7687433_7 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000116 118.0
HKD1_k127_7687433_8 Thioredoxin - - - 0.0000000000000000000000003186 111.0
HKD1_k127_7687433_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000004179 108.0
HKD1_k127_7716616_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
HKD1_k127_7716616_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
HKD1_k127_7716616_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000006476 192.0
HKD1_k127_7716616_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000008694 122.0
HKD1_k127_7763492_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 466.0
HKD1_k127_7763492_1 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002445 250.0
HKD1_k127_7763492_2 zinc-ribbon domain - - - 0.000000000000000000000000000005027 130.0
HKD1_k127_7763492_3 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000007001 129.0
HKD1_k127_7763492_4 HEAT repeat - - - 0.00000000000000000001572 102.0
HKD1_k127_7776131_0 Elongation factor G, domain IV K02355 - - 1.807e-232 738.0
HKD1_k127_7776131_1 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000003964 153.0
HKD1_k127_7776131_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000001793 57.0
HKD1_k127_7788977_0 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002003 244.0
HKD1_k127_7788977_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000087 231.0
HKD1_k127_7788977_2 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
HKD1_k127_7792579_0 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000002111 201.0
HKD1_k127_7792579_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000002182 173.0
HKD1_k127_7792579_2 transcription regulator activity - - - 0.0000000000000000000000000000000005837 135.0
HKD1_k127_7792579_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000154 129.0
HKD1_k127_7792579_4 polygalacturonase activity - - - 0.00000000000000004208 96.0
HKD1_k127_7792579_5 Belongs to the peptidase S8 family K14645 - - 0.000000000001169 82.0
HKD1_k127_7792579_6 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000002593 59.0
HKD1_k127_7804573_0 Protein kinase domain K12132 - 2.7.11.1 4.896e-211 676.0
HKD1_k127_7804573_1 carbonate dehydratase activity K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000009852 244.0
HKD1_k127_7804573_2 BON domain - - - 0.00000000000003941 74.0
HKD1_k127_7807895_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 571.0
HKD1_k127_7807895_1 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 355.0
HKD1_k127_7807895_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 288.0
HKD1_k127_7807895_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003471 286.0
HKD1_k127_7807895_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000004119 187.0
HKD1_k127_7807895_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000265 168.0
HKD1_k127_7807895_6 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.000000000000000000000000000000000003766 142.0
HKD1_k127_783192_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.246e-251 791.0
HKD1_k127_783192_1 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000002746 181.0
HKD1_k127_7862340_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 348.0
HKD1_k127_7862340_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 342.0
HKD1_k127_7862340_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
HKD1_k127_7862340_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001991 187.0
HKD1_k127_7862340_4 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000006798 132.0
HKD1_k127_7862340_5 heat shock protein binding K05516,K05801 - - 0.00000000000000000000000002323 123.0
HKD1_k127_7862340_6 Protein of unknown function (DUF1778) - - - 0.000000000000000000000003589 104.0
HKD1_k127_7862340_8 Mitochondrial K+-H+ exchange-related - - - 0.00003322 54.0
HKD1_k127_7862340_9 Major Facilitator Superfamily - - - 0.0001945 46.0
HKD1_k127_7865584_0 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009521 277.0
HKD1_k127_7865584_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009278 264.0
HKD1_k127_7865584_2 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 243.0
HKD1_k127_7865584_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
HKD1_k127_7865584_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001097 172.0
HKD1_k127_7865584_5 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000001182 91.0
HKD1_k127_7872784_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 604.0
HKD1_k127_7872784_1 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000005044 246.0
HKD1_k127_7872784_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 256.0
HKD1_k127_7872784_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000003422 242.0
HKD1_k127_7872784_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000001862 214.0
HKD1_k127_7872784_5 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000001696 152.0
HKD1_k127_7872784_6 Fibronectin type 3 domain K06882 - - 0.00000000000000000001958 106.0
HKD1_k127_7872784_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000002151 78.0
HKD1_k127_7872784_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0001668 44.0
HKD1_k127_7872784_9 CBS domain K03699 - - 0.000229 51.0
HKD1_k127_7878519_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003901 218.0
HKD1_k127_7878519_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001227 216.0
HKD1_k127_7878519_2 glycosyl transferase family 2 K20444 - - 0.0000000000000103 85.0
HKD1_k127_7895363_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 481.0
HKD1_k127_7895363_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
HKD1_k127_7895363_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 335.0
HKD1_k127_7906024_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 517.0
HKD1_k127_7906024_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000002358 235.0
HKD1_k127_7906024_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000005834 156.0
HKD1_k127_7906024_3 mttA/Hcf106 family K03116 - - 0.000000000000005082 76.0
HKD1_k127_7906024_4 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.00009868 54.0
HKD1_k127_7923006_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.132e-228 715.0
HKD1_k127_7923006_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 483.0
HKD1_k127_7923006_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001424 70.0
HKD1_k127_7923006_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 362.0
HKD1_k127_7923006_3 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 346.0
HKD1_k127_7923006_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 304.0
HKD1_k127_7923006_5 intracellular protease K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000788 206.0
HKD1_k127_7923006_6 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000008552 131.0
HKD1_k127_7923006_7 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000002602 119.0
HKD1_k127_7923006_8 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000002731 104.0
HKD1_k127_7923006_9 Methyltransferase domain - - - 0.00000000000000000006917 101.0
HKD1_k127_7925811_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 419.0
HKD1_k127_7925811_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
HKD1_k127_7946013_0 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 582.0
HKD1_k127_7946013_1 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003413 281.0
HKD1_k127_7946013_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000168 164.0
HKD1_k127_7946013_3 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001653 150.0
HKD1_k127_7946013_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000003431 133.0
HKD1_k127_7946013_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000001168 120.0
HKD1_k127_7946013_6 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000005001 111.0
HKD1_k127_7946013_7 FeoA domain K04758 - - 0.00000005856 57.0
HKD1_k127_7952728_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.519e-219 694.0
HKD1_k127_7952728_1 transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000001568 239.0
HKD1_k127_7957839_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000001313 132.0
HKD1_k127_7957839_1 chitinase K01183 - 3.2.1.14 0.0000000000000000000000001842 120.0
HKD1_k127_7957839_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000007856 118.0
HKD1_k127_7965933_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 476.0
HKD1_k127_7965933_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 407.0
HKD1_k127_7965933_2 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009655 274.0
HKD1_k127_7965933_3 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000004255 158.0
HKD1_k127_7965933_4 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000002146 132.0
HKD1_k127_7979766_0 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 4.714e-221 691.0
HKD1_k127_7979766_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 299.0
HKD1_k127_7980527_0 Acetyl-coenzyme A transporter 1 K08218 - - 2.632e-207 657.0
HKD1_k127_7980527_1 response regulator receiver K03413 - - 0.000000000000000000000000000000000000002582 158.0
HKD1_k127_7980527_2 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000001208 148.0
HKD1_k127_7980527_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000003327 140.0
HKD1_k127_7980527_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000002581 113.0
HKD1_k127_7980527_5 PFAM peptidase - - - 0.000000000000000000000008142 117.0
HKD1_k127_7984923_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 411.0
HKD1_k127_7984923_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 328.0
HKD1_k127_7984923_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000008539 208.0
HKD1_k127_7984923_3 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.0000000000000000000000000000000000000001163 169.0
HKD1_k127_7991610_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 344.0
HKD1_k127_7991610_1 COG2771 DNA-binding HTH domain-containing proteins - - - 0.000000000000000000000000000001802 132.0
HKD1_k127_7997436_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 605.0
HKD1_k127_7997436_1 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000114 145.0
HKD1_k127_7997436_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000009062 120.0
HKD1_k127_7997436_3 Tetratricopeptide repeat - - - 0.000000000000000000079 97.0
HKD1_k127_800091_0 PFAM band 7 protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
HKD1_k127_800091_1 COG0666 FOG Ankyrin repeat K06867 - - 0.00000000000000000000009977 108.0
HKD1_k127_800091_2 cellular response to DNA damage stimulus K07340 - - 0.0000000000000000000002343 106.0
HKD1_k127_8038555_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
HKD1_k127_8038555_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009272 279.0
HKD1_k127_8038555_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
HKD1_k127_827717_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 547.0
HKD1_k127_827717_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.0000000000000000000000000000000000000000000000000000404 197.0
HKD1_k127_827717_2 integral membrane protein - - - 0.0000327 56.0
HKD1_k127_875735_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 537.0
HKD1_k127_875735_1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000000000000000000000002034 145.0
HKD1_k127_878224_0 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1022.0
HKD1_k127_878224_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 402.0
HKD1_k127_878224_2 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HKD1_k127_899088_0 PFAM carboxyl transferase K01969 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 454.0
HKD1_k127_899088_1 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 389.0
HKD1_k127_899088_2 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004687 266.0
HKD1_k127_899088_3 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000004393 228.0
HKD1_k127_899088_4 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000000000007712 198.0
HKD1_k127_90483_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 531.0
HKD1_k127_90483_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000001468 203.0
HKD1_k127_90483_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000002045 168.0
HKD1_k127_90483_3 Tetratricopeptide repeat - - - 0.000000000000000000003283 109.0
HKD1_k127_90483_4 Domain of unknown function (DUF1844) - - - 0.0000000001035 67.0
HKD1_k127_908172_0 Catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 330.0
HKD1_k127_908172_1 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001366 277.0
HKD1_k127_908172_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000006614 233.0
HKD1_k127_908172_3 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000343 205.0
HKD1_k127_920292_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 472.0
HKD1_k127_920292_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001647 282.0
HKD1_k127_920292_3 Surface antigen K07277,K09800 - - 0.0000000000000000000000000000000000000000000005876 177.0
HKD1_k127_920292_4 COG0457 FOG TPR repeat - - - 0.00000000000006507 81.0
HKD1_k127_926469_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.852e-240 756.0
HKD1_k127_926469_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 469.0
HKD1_k127_926469_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005484 280.0
HKD1_k127_926469_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
HKD1_k127_926469_4 zeta toxin - - - 0.0000000000000000000000000000000000000000000000000000001211 205.0
HKD1_k127_926469_5 Phospholipid methyltransferase - - - 0.00000000000004112 78.0
HKD1_k127_926469_6 Acyltransferase family - - - 0.0008582 48.0
HKD1_k127_933295_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1313.0
HKD1_k127_933295_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
HKD1_k127_934700_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.098e-254 797.0
HKD1_k127_934700_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 442.0
HKD1_k127_934700_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 366.0
HKD1_k127_934700_3 Rubredoxin - - - 0.000000000000000002151 86.0
HKD1_k127_934700_4 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000002687 86.0
HKD1_k127_934700_5 Protein of unknown function (DUF1706) - - - 0.00000000000001112 82.0
HKD1_k127_939804_0 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 347.0
HKD1_k127_939804_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000005824 248.0
HKD1_k127_939804_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000005069 158.0
HKD1_k127_939804_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000002702 106.0
HKD1_k127_939804_4 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000003293 92.0
HKD1_k127_939804_5 Rieske [2Fe-2S] domain K00240,K02636,K03886 - 1.10.9.1,1.3.5.1,1.3.5.4 0.00000000000003096 73.0
HKD1_k127_949152_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.37e-213 666.0
HKD1_k127_949152_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 478.0
HKD1_k127_949152_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 373.0
HKD1_k127_949152_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 303.0
HKD1_k127_95044_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 607.0
HKD1_k127_95044_1 heat shock protein 70 K04043,K04044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 614.0
HKD1_k127_95044_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 372.0
HKD1_k127_95044_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000006235 221.0
HKD1_k127_95044_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000003962 175.0
HKD1_k127_95044_5 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000001251 132.0
HKD1_k127_95044_6 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000002156 107.0
HKD1_k127_95044_7 DnaJ molecular chaperone homology domain K04082 - - 0.00000000000000000000002111 109.0
HKD1_k127_95044_8 Transcriptional regulator - - - 0.000000000421 66.0
HKD1_k127_95044_9 Protein tyrosine kinase - - - 0.0007843 43.0
HKD1_k127_956817_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 562.0
HKD1_k127_956817_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 332.0
HKD1_k127_956817_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000006435 95.0
HKD1_k127_956817_3 peptidyl-tyrosine sulfation - - - 0.00000000000005203 79.0
HKD1_k127_970154_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 609.0
HKD1_k127_970154_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001042 291.0
HKD1_k127_986811_0 PFAM peptidase M13 K07386 - - 1.251e-265 835.0
HKD1_k127_986811_1 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 464.0
HKD1_k127_986811_2 Alpha/beta hydrolase family K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 381.0
HKD1_k127_986811_3 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 368.0
HKD1_k127_986811_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000147 271.0
HKD1_k127_986811_5 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
HKD1_k127_98910_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
HKD1_k127_98910_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000003011 190.0
HKD1_k127_98910_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000004516 73.0
HKD1_k127_995108_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 2.062e-217 683.0
HKD1_k127_995108_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 477.0
HKD1_k127_995108_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 446.0