Overview

ID MAG01724
Name HKD1_bin.41
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family UBA5066
Genus DAOMFB01
Species
Assembly information
Completeness (%) 66.78
Contamination (%) 1.03
GC content (%) 70.0
N50 (bp) 13,717
Genome size (bp) 2,382,183

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1994

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1062914_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000003108 190.0
HKD1_k127_1062914_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000003083 186.0
HKD1_k127_1062914_2 Doxx family K15977 - - 0.0000000000000000000000000000000000000000005867 161.0
HKD1_k127_1062914_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000003714 148.0
HKD1_k127_1062914_4 non-ribosomal peptide synthetase - - - 0.00000000000000000000000000000118 141.0
HKD1_k127_1062914_5 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000001063 130.0
HKD1_k127_1062914_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000004509 77.0
HKD1_k127_107806_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 595.0
HKD1_k127_107806_1 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 402.0
HKD1_k127_107806_10 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000451 204.0
HKD1_k127_107806_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000001033 189.0
HKD1_k127_107806_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000001462 184.0
HKD1_k127_107806_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000009569 187.0
HKD1_k127_107806_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000009544 189.0
HKD1_k127_107806_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000276 173.0
HKD1_k127_107806_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000012 169.0
HKD1_k127_107806_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000001934 160.0
HKD1_k127_107806_18 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000001465 160.0
HKD1_k127_107806_19 structural constituent of ribosome K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005307 156.0
HKD1_k127_107806_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 374.0
HKD1_k127_107806_20 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001506 156.0
HKD1_k127_107806_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000009012 149.0
HKD1_k127_107806_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000001266 130.0
HKD1_k127_107806_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000008722 124.0
HKD1_k127_107806_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000006229 114.0
HKD1_k127_107806_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000009227 93.0
HKD1_k127_107806_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000005242 101.0
HKD1_k127_107806_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001611 83.0
HKD1_k127_107806_28 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001906 85.0
HKD1_k127_107806_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000201 70.0
HKD1_k127_107806_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 376.0
HKD1_k127_107806_30 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000002666 70.0
HKD1_k127_107806_31 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000004345 61.0
HKD1_k127_107806_32 Protein of unknown function (DUF3592) - - - 0.00006424 50.0
HKD1_k127_107806_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
HKD1_k127_107806_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006037 275.0
HKD1_k127_107806_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 273.0
HKD1_k127_107806_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003749 258.0
HKD1_k127_107806_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
HKD1_k127_107806_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001455 204.0
HKD1_k127_1081684_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 1.323e-225 715.0
HKD1_k127_1081684_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 1.184e-214 674.0
HKD1_k127_1081684_10 ADP binding - - - 0.000000000000000000000000000000000000000000000000000009609 215.0
HKD1_k127_1081684_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000002185 179.0
HKD1_k127_1081684_12 Dynamin family - - - 0.000000000000000000000000000000000000000000000154 189.0
HKD1_k127_1081684_13 TIGRFAM phosphoesterase, MJ0936 family - - - 0.0000000000000000000000000000000001128 151.0
HKD1_k127_1081684_14 Citrate transporter - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001191 137.0
HKD1_k127_1081684_16 PFAM Methyltransferase type 11 K03892 - - 0.0000000000009393 79.0
HKD1_k127_1081684_18 PFAM peptidase M48 Ste24p - - - 0.00000000483 68.0
HKD1_k127_1081684_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 421.0
HKD1_k127_1081684_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 392.0
HKD1_k127_1081684_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 357.0
HKD1_k127_1081684_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 301.0
HKD1_k127_1081684_6 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002536 287.0
HKD1_k127_1081684_7 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002135 276.0
HKD1_k127_1081684_8 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008908 277.0
HKD1_k127_1081684_9 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009674 264.0
HKD1_k127_1114415_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
HKD1_k127_1114415_1 PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000001251 203.0
HKD1_k127_1114415_2 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000009078 161.0
HKD1_k127_1114415_3 response regulator, receiver - - - 0.000000000000000000000000000000001192 143.0
HKD1_k127_116219_0 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 486.0
HKD1_k127_116219_1 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 327.0
HKD1_k127_116219_2 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000006941 196.0
HKD1_k127_116219_3 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000156 143.0
HKD1_k127_116219_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000004023 85.0
HKD1_k127_116219_5 - - - - 0.00003292 49.0
HKD1_k127_116219_6 DNA primase - - - 0.0001211 45.0
HKD1_k127_1187516_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000004305 139.0
HKD1_k127_1187516_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000004235 132.0
HKD1_k127_1187516_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - - 0.000000000000000007899 94.0
HKD1_k127_1190446_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 406.0
HKD1_k127_1190446_1 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000001151 267.0
HKD1_k127_1190446_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0008092 49.0
HKD1_k127_1190446_2 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 263.0
HKD1_k127_1190446_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005995 273.0
HKD1_k127_1190446_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001082 217.0
HKD1_k127_1190446_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000001462 221.0
HKD1_k127_1190446_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000001121 161.0
HKD1_k127_1190446_7 phosphorelay signal transduction system - - - 0.00000000000000000000000004656 113.0
HKD1_k127_1190446_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000002143 106.0
HKD1_k127_1190446_9 ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.000004169 60.0
HKD1_k127_1199612_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.124e-199 651.0
HKD1_k127_1199612_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
HKD1_k127_1199612_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 357.0
HKD1_k127_1199612_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000008906 189.0
HKD1_k127_1199612_4 PHP domain K04477 - - 0.000000000000000000000000000000000000000000000001749 189.0
HKD1_k127_1199612_5 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000001378 138.0
HKD1_k127_1199612_6 RNase H K03469 - 3.1.26.4 0.00000000000000000001047 102.0
HKD1_k127_1199612_7 C4-type zinc ribbon domain K07164 - - 0.000000000000001822 86.0
HKD1_k127_1199612_8 PFAM DivIVA K04074 - - 0.000000000000006162 81.0
HKD1_k127_1199612_9 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000005194 69.0
HKD1_k127_1221514_0 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000001455 196.0
HKD1_k127_1221514_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000002769 141.0
HKD1_k127_1221514_2 4Fe-4S binding domain - - - 0.00000000000000000000000000001505 120.0
HKD1_k127_1221514_3 Histidine kinase K07652 - 2.7.13.3 0.000000000000000000000002185 117.0
HKD1_k127_1221514_4 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000007593 108.0
HKD1_k127_1241375_0 DNA polymerase beta thumb - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 325.0
HKD1_k127_1241375_1 proteins of the AP superfamily - - - 0.00000000008214 76.0
HKD1_k127_1241375_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000001061 64.0
HKD1_k127_1355150_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.241e-241 777.0
HKD1_k127_1355150_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 2.318e-202 655.0
HKD1_k127_1355150_10 MobA-like NTP transferase domain - - - 0.00000000000001471 83.0
HKD1_k127_1355150_11 Mitochondrial biogenesis AIM24 - - - 0.0000000008748 71.0
HKD1_k127_1355150_12 Modulates RecA activity K03565 - - 0.00000000413 69.0
HKD1_k127_1355150_13 Mitochondrial biogenesis AIM24 - - - 0.000002267 60.0
HKD1_k127_1355150_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 539.0
HKD1_k127_1355150_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
HKD1_k127_1355150_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 326.0
HKD1_k127_1355150_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000183 286.0
HKD1_k127_1355150_6 [2Fe-2S] binding domain K07302,K13483 - 1.3.99.16 0.00000000000000000000000000000000000000000000000001666 187.0
HKD1_k127_1355150_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000002227 171.0
HKD1_k127_1355150_8 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000002122 171.0
HKD1_k127_1355150_9 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000004956 144.0
HKD1_k127_1392621_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.537e-277 877.0
HKD1_k127_1392621_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
HKD1_k127_1392621_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 439.0
HKD1_k127_1392621_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00375,K05825,K16422,K16423 - 1.1.3.46,2.6.1.103 0.000000000000000000000000000000000000000000000000000000000000000001386 246.0
HKD1_k127_1392621_4 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000004998 231.0
HKD1_k127_1392621_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000719 205.0
HKD1_k127_1392621_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000002512 189.0
HKD1_k127_140074_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 552.0
HKD1_k127_140074_1 Belongs to the OprB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 302.0
HKD1_k127_140074_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000001639 192.0
HKD1_k127_140074_3 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000007747 142.0
HKD1_k127_140074_4 PFAM MgtC family K07507 - - 0.00000000000000000000000000002413 124.0
HKD1_k127_140074_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000004311 111.0
HKD1_k127_1416737_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 516.0
HKD1_k127_1416737_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 443.0
HKD1_k127_1422540_0 Protein kinase domain K12132 - 2.7.11.1 5.406e-262 844.0
HKD1_k127_1422540_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 371.0
HKD1_k127_1422540_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 302.0
HKD1_k127_1422540_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000006271 230.0
HKD1_k127_1422540_4 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000000000000000000000001333 206.0
HKD1_k127_1422540_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000347 122.0
HKD1_k127_1422540_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000007368 70.0
HKD1_k127_1447684_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 2.457e-212 668.0
HKD1_k127_1447684_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 468.0
HKD1_k127_1447684_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000001179 115.0
HKD1_k127_1447684_11 - - - - 0.00000000000000000000000201 114.0
HKD1_k127_1447684_12 DinB superfamily - - - 0.0000000000000000000000176 108.0
HKD1_k127_1447684_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000002178 105.0
HKD1_k127_1447684_14 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000001752 107.0
HKD1_k127_1447684_15 Methyltransferase domain - - - 0.00000000000000002924 96.0
HKD1_k127_1447684_16 Regulatory protein, FmdB - - - 0.000000000000001074 89.0
HKD1_k127_1447684_17 Domain of unknown function (DUF4388) - - - 0.00000000000242 78.0
HKD1_k127_1447684_18 SpoVT / AbrB like domain - - - 0.000000000002947 69.0
HKD1_k127_1447684_19 - - - - 0.0000005003 63.0
HKD1_k127_1447684_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 455.0
HKD1_k127_1447684_20 HEAT repeats - - - 0.0004445 53.0
HKD1_k127_1447684_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 426.0
HKD1_k127_1447684_4 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 394.0
HKD1_k127_1447684_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 334.0
HKD1_k127_1447684_6 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008259 275.0
HKD1_k127_1447684_7 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003692 247.0
HKD1_k127_1447684_8 FAD binding domain - - - 0.00000000000000000000000000000000000000000001751 183.0
HKD1_k127_1447684_9 Two component regulator propeller - - - 0.0000000000000000000000000000001184 143.0
HKD1_k127_1466569_0 Major Facilitator Superfamily - - - 1.761e-195 618.0
HKD1_k127_1466569_1 oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 316.0
HKD1_k127_1466569_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 297.0
HKD1_k127_1466569_3 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
HKD1_k127_1466569_4 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000007362 176.0
HKD1_k127_1466569_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000002208 157.0
HKD1_k127_1466569_6 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000000003021 171.0
HKD1_k127_1466569_7 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.0000000000000000001616 89.0
HKD1_k127_1502554_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 557.0
HKD1_k127_1502554_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 564.0
HKD1_k127_1502554_10 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000006231 136.0
HKD1_k127_1502554_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000001301 121.0
HKD1_k127_1502554_12 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000825 124.0
HKD1_k127_1502554_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000003399 110.0
HKD1_k127_1502554_14 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000008659 104.0
HKD1_k127_1502554_15 PFAM GCN5-related N-acetyltransferase - - - 0.000000001921 68.0
HKD1_k127_1502554_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000007671 64.0
HKD1_k127_1502554_17 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00004901 49.0
HKD1_k127_1502554_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 486.0
HKD1_k127_1502554_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 462.0
HKD1_k127_1502554_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 355.0
HKD1_k127_1502554_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 339.0
HKD1_k127_1502554_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HKD1_k127_1502554_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000001862 163.0
HKD1_k127_1502554_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.00000000000000000000000000000000001975 158.0
HKD1_k127_1502554_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000002195 145.0
HKD1_k127_151859_0 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003342 271.0
HKD1_k127_151859_1 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001549 208.0
HKD1_k127_151859_2 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000002358 152.0
HKD1_k127_151859_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000001516 108.0
HKD1_k127_1533367_0 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009347 289.0
HKD1_k127_1533367_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002195 300.0
HKD1_k127_1533367_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000001932 185.0
HKD1_k127_1597203_0 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 299.0
HKD1_k127_1597203_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000001014 223.0
HKD1_k127_1597203_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000002045 186.0
HKD1_k127_1597387_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 356.0
HKD1_k127_1597387_1 Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 333.0
HKD1_k127_1597387_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000002581 192.0
HKD1_k127_1597387_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000001335 149.0
HKD1_k127_1597387_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000007589 135.0
HKD1_k127_1597387_5 - - - - 0.000000000000000000000000001182 117.0
HKD1_k127_1597387_6 Bacterial regulatory proteins, tetR family - - - 0.00000000001103 73.0
HKD1_k127_1597387_7 Putative ATP-binding cassette K01992 - - 0.000004905 57.0
HKD1_k127_163682_0 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 402.0
HKD1_k127_163682_1 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000002071 92.0
HKD1_k127_163682_2 - - - - 0.000000000000001192 84.0
HKD1_k127_1643634_0 Prolyl oligopeptidase family - - - 3.127e-209 674.0
HKD1_k127_1643634_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 572.0
HKD1_k127_1643634_2 ABC transporter K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
HKD1_k127_1643634_3 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 323.0
HKD1_k127_1643634_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
HKD1_k127_1643634_5 - - - - 0.0000000000000000000000000000000000000000000000000000001407 213.0
HKD1_k127_1643634_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000001165 130.0
HKD1_k127_1643634_7 - - - - 0.00003781 51.0
HKD1_k127_1658007_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.373e-233 734.0
HKD1_k127_1658007_1 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 481.0
HKD1_k127_1658007_10 - - - - 0.0000000000001234 73.0
HKD1_k127_1658007_11 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000002089 75.0
HKD1_k127_1658007_12 OsmC-like protein - - - 0.0000000001514 64.0
HKD1_k127_1658007_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HKD1_k127_1658007_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008636 259.0
HKD1_k127_1658007_4 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001403 227.0
HKD1_k127_1658007_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000004913 149.0
HKD1_k127_1658007_6 ABC-2 family transporter protein - - - 0.000000000000000000000000000000001342 150.0
HKD1_k127_1658007_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000001578 139.0
HKD1_k127_1658007_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000007557 105.0
HKD1_k127_1658007_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000004017 99.0
HKD1_k127_1676637_0 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000337 253.0
HKD1_k127_1676637_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000005754 188.0
HKD1_k127_1676637_2 Redoxin - - - 0.0000000000000004555 89.0
HKD1_k127_1719448_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.164e-232 739.0
HKD1_k127_1719448_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 342.0
HKD1_k127_1719448_10 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000003805 79.0
HKD1_k127_1719448_11 Putative Ig domain - - - 0.000000002078 71.0
HKD1_k127_1719448_12 PFAM Fimbrial assembly family protein K02663 - - 0.000000005659 65.0
HKD1_k127_1719448_13 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.0000000245 67.0
HKD1_k127_1719448_14 IPT/TIG domain - - - 0.000006226 60.0
HKD1_k127_1719448_15 Pilus assembly protein, PilP K02664,K02665 - - 0.0001427 51.0
HKD1_k127_1719448_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 349.0
HKD1_k127_1719448_3 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 316.0
HKD1_k127_1719448_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000048 276.0
HKD1_k127_1719448_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
HKD1_k127_1719448_6 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000175 206.0
HKD1_k127_1719448_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000001901 135.0
HKD1_k127_1719448_8 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000001733 110.0
HKD1_k127_1719448_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000001141 89.0
HKD1_k127_1745311_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 355.0
HKD1_k127_1745311_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000003245 160.0
HKD1_k127_1745311_2 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000003094 126.0
HKD1_k127_1778844_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 417.0
HKD1_k127_1778844_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 336.0
HKD1_k127_1778844_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003713 281.0
HKD1_k127_1778844_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000005252 243.0
HKD1_k127_1778844_4 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000001255 131.0
HKD1_k127_1778844_5 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000007858 103.0
HKD1_k127_1778844_6 phosphocarrier protein HPr K11189 - - 0.0000000000000000000004403 100.0
HKD1_k127_1778844_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000005066 70.0
HKD1_k127_1778844_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000001511 71.0
HKD1_k127_1779754_0 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000001994 130.0
HKD1_k127_1809842_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 370.0
HKD1_k127_1809842_1 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 319.0
HKD1_k127_1809842_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 288.0
HKD1_k127_1847759_0 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 380.0
HKD1_k127_1847759_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 382.0
HKD1_k127_1847759_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
HKD1_k127_1847759_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000009004 158.0
HKD1_k127_1862257_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 405.0
HKD1_k127_1862257_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 274.0
HKD1_k127_1862257_2 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
HKD1_k127_1862257_3 Flavoprotein K03186 - 2.5.1.129 0.000000000000000000000000000000000001147 151.0
HKD1_k127_1862257_4 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000005967 132.0
HKD1_k127_1862257_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000006607 117.0
HKD1_k127_1862257_6 CYTH K05873 - 4.6.1.1 0.000000000000000000001991 111.0
HKD1_k127_1862257_7 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000002528 89.0
HKD1_k127_1862257_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000005918 64.0
HKD1_k127_1862257_9 Type II transport protein GspH K08084 - - 0.0008945 50.0
HKD1_k127_1865130_0 cellulose binding - - - 0.0 1145.0
HKD1_k127_1865130_1 Hydrolase CocE NonD family - - - 1.122e-314 975.0
HKD1_k127_1865130_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 508.0
HKD1_k127_1865130_3 PFAM Acyl-CoA dehydrogenase K09456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 498.0
HKD1_k127_1865130_4 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 385.0
HKD1_k127_1865130_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 374.0
HKD1_k127_1865130_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000008012 199.0
HKD1_k127_1865130_7 Transglutaminase-like superfamily - - - 0.000000000000000000000000000004913 124.0
HKD1_k127_1872072_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.288e-235 743.0
HKD1_k127_1872072_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 443.0
HKD1_k127_1872072_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000646 285.0
HKD1_k127_1872072_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005308 273.0
HKD1_k127_1872072_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000007231 211.0
HKD1_k127_1872072_5 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000007595 62.0
HKD1_k127_1914819_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 310.0
HKD1_k127_1914819_1 CoA binding domain K06929 - - 0.00000000000000000000000000000000002704 140.0
HKD1_k127_1914819_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000001966 103.0
HKD1_k127_1914819_3 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000003907 72.0
HKD1_k127_193361_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.594e-261 819.0
HKD1_k127_193361_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000001811 138.0
HKD1_k127_193361_2 - - - - 0.000000000000000001182 98.0
HKD1_k127_1967071_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 6.658e-199 632.0
HKD1_k127_1967071_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 353.0
HKD1_k127_1967071_2 PFAM peptidase S1 and S6 chymotrypsin Hap K08070 - 1.3.1.74 0.0002586 47.0
HKD1_k127_199711_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 439.0
HKD1_k127_199711_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 387.0
HKD1_k127_2037255_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1325.0
HKD1_k127_2037255_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.527e-211 664.0
HKD1_k127_2037255_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 419.0
HKD1_k127_2037255_3 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 377.0
HKD1_k127_2037255_4 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008019 270.0
HKD1_k127_2037255_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 260.0
HKD1_k127_2037255_6 YXWGXW repeat (2 copies) - - - 0.00000000000000000006045 94.0
HKD1_k127_2065986_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 597.0
HKD1_k127_2065986_1 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 543.0
HKD1_k127_2065986_10 PFAM response regulator receiver - - - 0.000000000000000000000000000000000007972 139.0
HKD1_k127_2065986_11 response regulator, receiver - - - 0.0000000000000000000000000215 123.0
HKD1_k127_2065986_12 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000001704 95.0
HKD1_k127_2065986_13 - - - - 0.00001536 55.0
HKD1_k127_2065986_14 - - - - 0.00008955 49.0
HKD1_k127_2065986_2 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 456.0
HKD1_k127_2065986_3 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 449.0
HKD1_k127_2065986_4 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 467.0
HKD1_k127_2065986_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 368.0
HKD1_k127_2065986_6 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 360.0
HKD1_k127_2065986_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003868 266.0
HKD1_k127_2065986_8 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000001375 177.0
HKD1_k127_2065986_9 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000004198 154.0
HKD1_k127_2066480_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
HKD1_k127_2066480_1 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002599 264.0
HKD1_k127_2066480_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000001313 153.0
HKD1_k127_2066480_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000003151 150.0
HKD1_k127_2066480_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000476 111.0
HKD1_k127_2067889_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.766e-239 761.0
HKD1_k127_2067889_1 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 390.0
HKD1_k127_2067889_10 Belongs to the UPF0271 (lamB) family K07160 - - 0.0001846 44.0
HKD1_k127_2067889_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 388.0
HKD1_k127_2067889_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 325.0
HKD1_k127_2067889_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000002296 221.0
HKD1_k127_2067889_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000003973 192.0
HKD1_k127_2067889_6 isomerase K03271 - 5.3.1.28 0.00000000000000000000000000000000000000001982 170.0
HKD1_k127_2067889_7 peroxiredoxin activity - - - 0.000000000000000000000000000000000001706 160.0
HKD1_k127_2067889_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000004706 107.0
HKD1_k127_2067889_9 cell redox homeostasis - - - 0.0000000000000000004619 100.0
HKD1_k127_208551_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 520.0
HKD1_k127_208551_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 509.0
HKD1_k127_208551_10 GAF domain - - - 0.000000000000000000000000000000000000008067 166.0
HKD1_k127_208551_11 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000003717 156.0
HKD1_k127_208551_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000641 147.0
HKD1_k127_208551_13 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000002521 141.0
HKD1_k127_208551_14 endoglucanase-related protein, glucosyl hydrolase family 9 protein - - - 0.000000000000187 81.0
HKD1_k127_208551_15 Oxygen tolerance - - - 0.0000000289 67.0
HKD1_k127_208551_16 Psort location CytoplasmicMembrane, score - - - 0.00004104 57.0
HKD1_k127_208551_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 504.0
HKD1_k127_208551_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
HKD1_k127_208551_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 408.0
HKD1_k127_208551_5 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 289.0
HKD1_k127_208551_6 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 265.0
HKD1_k127_208551_7 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000004386 211.0
HKD1_k127_208551_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000004664 189.0
HKD1_k127_208551_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000002815 170.0
HKD1_k127_2093045_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 572.0
HKD1_k127_2093045_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 557.0
HKD1_k127_2093045_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000001141 267.0
HKD1_k127_2093045_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001139 247.0
HKD1_k127_2093045_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000001188 111.0
HKD1_k127_2093045_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0006215 44.0
HKD1_k127_2151602_0 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 471.0
HKD1_k127_2151602_1 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 339.0
HKD1_k127_2151602_2 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 325.0
HKD1_k127_2151602_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000001047 202.0
HKD1_k127_2151602_4 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000001822 184.0
HKD1_k127_2151602_5 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000003451 128.0
HKD1_k127_2151602_6 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000001626 92.0
HKD1_k127_2151602_7 histidine kinase A domain protein K02484 - 2.7.13.3 0.000000000000002849 90.0
HKD1_k127_2168188_0 Belongs to the GarS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 353.0
HKD1_k127_2168188_1 PFAM response regulator receiver - - - 0.000000000000000000000000000001995 128.0
HKD1_k127_2168188_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000001149 102.0
HKD1_k127_2171111_0 domain protein K20276 - - 0.00000000005237 76.0
HKD1_k127_2231896_0 B12 binding domain - - - 8.472e-197 631.0
HKD1_k127_2231896_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 541.0
HKD1_k127_2231896_10 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000006115 105.0
HKD1_k127_2231896_11 oxidoreductase activity - - - 0.0000000000000000002441 104.0
HKD1_k127_2231896_12 SMART Tetratricopeptide - - - 0.00000000000001455 82.0
HKD1_k127_2231896_13 Belongs to the ompA family K03286 - - 0.00000000000003669 81.0
HKD1_k127_2231896_15 VanZ like family - - - 0.0002265 55.0
HKD1_k127_2231896_16 Tetratricopeptide repeat - - - 0.0002915 50.0
HKD1_k127_2231896_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 493.0
HKD1_k127_2231896_3 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 469.0
HKD1_k127_2231896_4 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001142 297.0
HKD1_k127_2231896_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003809 284.0
HKD1_k127_2231896_6 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002384 266.0
HKD1_k127_2231896_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000004033 198.0
HKD1_k127_2231896_8 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000001172 148.0
HKD1_k127_2231896_9 protein family UPF0079, ATPase K06925 - - 0.00000000000000000001451 101.0
HKD1_k127_2242527_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1180.0
HKD1_k127_2242527_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.218e-215 704.0
HKD1_k127_2242527_10 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
HKD1_k127_2242527_11 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000001466 197.0
HKD1_k127_2242527_12 phenazine biosynthesis protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000001298 188.0
HKD1_k127_2242527_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000007966 175.0
HKD1_k127_2242527_14 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000001367 118.0
HKD1_k127_2242527_15 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000537 93.0
HKD1_k127_2242527_16 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000001141 91.0
HKD1_k127_2242527_17 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000006221 84.0
HKD1_k127_2242527_18 Bacterial regulatory proteins, tetR family - - - 0.00000000000001178 85.0
HKD1_k127_2242527_19 PA14 domain - - - 0.00000000002318 76.0
HKD1_k127_2242527_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 503.0
HKD1_k127_2242527_20 Cytochrome c - - - 0.0000000000858 68.0
HKD1_k127_2242527_21 Protein of unknown function (DUF1573) - - - 0.00000000009524 74.0
HKD1_k127_2242527_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 456.0
HKD1_k127_2242527_4 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 394.0
HKD1_k127_2242527_5 PFAM Peptidase family M20 M25 M40 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 303.0
HKD1_k127_2242527_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 274.0
HKD1_k127_2242527_7 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
HKD1_k127_2242527_8 of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002068 267.0
HKD1_k127_2242527_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000002046 237.0
HKD1_k127_2260204_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 2.361e-263 824.0
HKD1_k127_2260204_1 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 584.0
HKD1_k127_2260204_10 protein histidine kinase activity K06375 - - 0.0000000000000000000000007107 113.0
HKD1_k127_2260204_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000001668 118.0
HKD1_k127_2260204_12 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17 0.0000000000000000000001292 98.0
HKD1_k127_2260204_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000902 106.0
HKD1_k127_2260204_14 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000001352 92.0
HKD1_k127_2260204_15 Cytochrome c K17223 - - 0.0000000000001148 85.0
HKD1_k127_2260204_16 Cytochrome c K02305,K07152 - - 0.0000000000008283 82.0
HKD1_k127_2260204_17 VanZ like family - - - 0.000000217 62.0
HKD1_k127_2260204_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 575.0
HKD1_k127_2260204_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 370.0
HKD1_k127_2260204_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 320.0
HKD1_k127_2260204_5 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004943 287.0
HKD1_k127_2260204_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002811 283.0
HKD1_k127_2260204_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000002204 260.0
HKD1_k127_2260204_8 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000000000004542 193.0
HKD1_k127_2260204_9 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000007125 121.0
HKD1_k127_2285870_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1045.0
HKD1_k127_2285870_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
HKD1_k127_2285870_2 - - - - 0.000000000000000000000000000000000000000000005738 170.0
HKD1_k127_2285870_3 Cytidylate kinase-like family - - - 0.000000000000000000000897 105.0
HKD1_k127_2322520_0 Multicopper oxidase K06324 - 1.16.3.3 3.088e-221 709.0
HKD1_k127_2322520_1 DNA RNA helicase, superfamily II, SNF2 family K08282 - 2.7.11.1 2.439e-207 685.0
HKD1_k127_2322520_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002162 111.0
HKD1_k127_2322520_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000003316 122.0
HKD1_k127_2322520_12 TPM domain - - - 0.000000000000000000000009752 108.0
HKD1_k127_2322520_13 Lytic murein transglycosylase K08309 - - 0.00000000000000000000005793 116.0
HKD1_k127_2322520_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000002168 102.0
HKD1_k127_2322520_15 SWIM zinc finger - - - 0.00000000000000005827 96.0
HKD1_k127_2322520_16 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000005349 59.0
HKD1_k127_2322520_17 - - - - 0.000002466 59.0
HKD1_k127_2322520_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 456.0
HKD1_k127_2322520_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 368.0
HKD1_k127_2322520_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000001554 215.0
HKD1_k127_2322520_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000007768 211.0
HKD1_k127_2322520_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000006798 194.0
HKD1_k127_2322520_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000001327 137.0
HKD1_k127_2322520_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000003436 144.0
HKD1_k127_2322520_9 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000005649 135.0
HKD1_k127_2339845_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.515e-273 858.0
HKD1_k127_2339845_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.84e-252 792.0
HKD1_k127_2339845_10 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 337.0
HKD1_k127_2339845_11 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 313.0
HKD1_k127_2339845_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
HKD1_k127_2339845_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000162 276.0
HKD1_k127_2339845_14 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000001274 229.0
HKD1_k127_2339845_15 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000001776 215.0
HKD1_k127_2339845_16 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000001916 215.0
HKD1_k127_2339845_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000006024 200.0
HKD1_k127_2339845_18 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000006537 181.0
HKD1_k127_2339845_19 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000008886 174.0
HKD1_k127_2339845_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.326e-237 741.0
HKD1_k127_2339845_20 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000466 164.0
HKD1_k127_2339845_21 PFAM alpha beta hydrolase fold - - - 0.000000000000000000005626 105.0
HKD1_k127_2339845_22 PFAM glycosyl transferase family 39 - - - 0.000000000000000002648 96.0
HKD1_k127_2339845_23 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000492 96.0
HKD1_k127_2339845_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000008213 82.0
HKD1_k127_2339845_25 - - - - 0.0000000000000009401 87.0
HKD1_k127_2339845_26 S4 RNA-binding domain K04762 - - 0.000000000000001229 84.0
HKD1_k127_2339845_27 Preprotein translocase SecG subunit K03075 - - 0.000000000000002353 81.0
HKD1_k127_2339845_28 COG0671 Membrane-associated phospholipid phosphatase - - - 0.000000000000006868 86.0
HKD1_k127_2339845_29 PAP2 superfamily - - - 0.00000000000001995 87.0
HKD1_k127_2339845_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.338e-229 720.0
HKD1_k127_2339845_30 fatty acid desaturase - - - 0.000000000001017 79.0
HKD1_k127_2339845_31 Domain of unknown function (DUF4870) - - - 0.00000001467 61.0
HKD1_k127_2339845_33 RDD family - - - 0.00006425 55.0
HKD1_k127_2339845_4 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 500.0
HKD1_k127_2339845_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 447.0
HKD1_k127_2339845_6 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 398.0
HKD1_k127_2339845_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
HKD1_k127_2339845_8 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 371.0
HKD1_k127_2339845_9 Glycosyltransferase like family 2 K00721,K20534 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 341.0
HKD1_k127_2392612_0 Dehydrogenase E1 component K11381 - 1.2.4.4 9.825e-301 940.0
HKD1_k127_2392612_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.835e-276 867.0
HKD1_k127_2392612_2 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000005296 228.0
HKD1_k127_2392612_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000004053 164.0
HKD1_k127_2392612_4 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000007145 159.0
HKD1_k127_2415853_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.625e-232 731.0
HKD1_k127_2415853_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 601.0
HKD1_k127_2415853_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 305.0
HKD1_k127_2415853_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000166 230.0
HKD1_k127_2415853_12 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000001365 190.0
HKD1_k127_2415853_13 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000015 179.0
HKD1_k127_2415853_14 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000001185 134.0
HKD1_k127_2415853_15 Modulator of DNA gyrase K03568 - - 0.000000000000000000000000001243 128.0
HKD1_k127_2415853_16 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.00000000000000000000000004006 126.0
HKD1_k127_2415853_17 PFAM Redoxin - - - 0.000000000000000000000009157 109.0
HKD1_k127_2415853_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000005137 96.0
HKD1_k127_2415853_19 DSBA-like thioredoxin domain - - - 0.00000000000000000269 98.0
HKD1_k127_2415853_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 505.0
HKD1_k127_2415853_20 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000002714 87.0
HKD1_k127_2415853_21 protein kinase activity - - - 0.00000000000004222 86.0
HKD1_k127_2415853_22 Biotin-requiring enzyme - - - 0.000000000001277 81.0
HKD1_k127_2415853_23 - - - - 0.0000000003209 68.0
HKD1_k127_2415853_24 Tetratricopeptide repeat - - - 0.00000001459 68.0
HKD1_k127_2415853_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 426.0
HKD1_k127_2415853_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 395.0
HKD1_k127_2415853_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 371.0
HKD1_k127_2415853_6 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 330.0
HKD1_k127_2415853_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 323.0
HKD1_k127_2415853_8 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HKD1_k127_2415853_9 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 311.0
HKD1_k127_24660_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002012 290.0
HKD1_k127_24660_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000003356 243.0
HKD1_k127_24660_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000004182 209.0
HKD1_k127_24660_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000002452 183.0
HKD1_k127_24660_4 Protein tyrosine kinase - - - 0.00000000000000000000000006049 123.0
HKD1_k127_24660_5 antisigma factor binding - - - 0.00000000000000000002181 95.0
HKD1_k127_24660_6 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000000001321 94.0
HKD1_k127_24660_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000007231 66.0
HKD1_k127_24660_8 O-methyltransferase - - - 0.000243 52.0
HKD1_k127_2480971_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 333.0
HKD1_k127_2480971_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001097 271.0
HKD1_k127_2480971_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000005801 274.0
HKD1_k127_2480971_3 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000007059 197.0
HKD1_k127_2480971_4 Psort location Cytoplasmic, score 8.96 K01808 - 5.3.1.6 0.0000000000000000000000000000005692 123.0
HKD1_k127_2480971_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000141 108.0
HKD1_k127_2490576_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 469.0
HKD1_k127_2490576_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 404.0
HKD1_k127_2490576_10 diguanylate cyclase - - - 0.0000000000000000000001956 114.0
HKD1_k127_2490576_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007131 297.0
HKD1_k127_2490576_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000001245 258.0
HKD1_k127_2490576_4 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000003889 206.0
HKD1_k127_2490576_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.000000000000000000000000000000000000000000000000000000008604 213.0
HKD1_k127_2490576_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000002541 207.0
HKD1_k127_2490576_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000001415 196.0
HKD1_k127_2490576_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000008942 184.0
HKD1_k127_2490576_9 - - - - 0.000000000000000000000000000000000000000002122 171.0
HKD1_k127_253160_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 542.0
HKD1_k127_253160_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 499.0
HKD1_k127_253160_2 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 237.0
HKD1_k127_253160_3 Redoxin - - - 0.000000000000000000005594 104.0
HKD1_k127_253160_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000001309 57.0
HKD1_k127_2546143_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 594.0
HKD1_k127_2546143_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 503.0
HKD1_k127_2546143_2 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001464 284.0
HKD1_k127_2546143_3 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006602 288.0
HKD1_k127_2546143_4 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001932 276.0
HKD1_k127_2546143_5 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000002674 174.0
HKD1_k127_2546143_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000007111 166.0
HKD1_k127_2546143_7 Fumble K09680 - 2.7.1.33 0.000000000000000000000000000003198 134.0
HKD1_k127_2546143_8 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000194 123.0
HKD1_k127_255455_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 592.0
HKD1_k127_2559019_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 1.464e-267 834.0
HKD1_k127_2559019_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 416.0
HKD1_k127_2559019_10 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000001185 219.0
HKD1_k127_2559019_11 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000006927 199.0
HKD1_k127_2559019_12 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000001531 192.0
HKD1_k127_2559019_13 - - - - 0.00000000000000000000000000000000000000003726 168.0
HKD1_k127_2559019_14 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.00000000000000000000000000000002584 128.0
HKD1_k127_2559019_15 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000001875 125.0
HKD1_k127_2559019_16 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.000000000000000000000001733 116.0
HKD1_k127_2559019_2 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 409.0
HKD1_k127_2559019_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 370.0
HKD1_k127_2559019_4 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 368.0
HKD1_k127_2559019_5 ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 371.0
HKD1_k127_2559019_6 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 316.0
HKD1_k127_2559019_7 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001692 289.0
HKD1_k127_2559019_8 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001263 259.0
HKD1_k127_2559019_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000009459 217.0
HKD1_k127_2584049_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 1.252e-194 621.0
HKD1_k127_2584049_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 585.0
HKD1_k127_2584049_10 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000004189 134.0
HKD1_k127_2584049_11 Universal stress protein family - - - 0.0000000000000000000000000003703 125.0
HKD1_k127_2584049_12 Peptidase, M28 - - - 0.000000000002357 80.0
HKD1_k127_2584049_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000003034 68.0
HKD1_k127_2584049_2 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 552.0
HKD1_k127_2584049_3 Leukotriene A4 hydrolase, C-terminal K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 533.0
HKD1_k127_2584049_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 384.0
HKD1_k127_2584049_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 350.0
HKD1_k127_2584049_6 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 339.0
HKD1_k127_2584049_7 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 315.0
HKD1_k127_2584049_8 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 298.0
HKD1_k127_2584049_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000001617 160.0
HKD1_k127_2590679_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 407.0
HKD1_k127_2590679_1 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000001456 252.0
HKD1_k127_2590679_2 Transcriptional regulator K13771 - - 0.0000283 51.0
HKD1_k127_2643575_0 acetyl-CoA hydrolase K18118 - 2.8.3.18 3.877e-237 745.0
HKD1_k127_2643575_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 524.0
HKD1_k127_2643575_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 355.0
HKD1_k127_2643575_3 - - - - 0.0000000000000000000000000000000000000000000000000001834 207.0
HKD1_k127_2643575_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000001579 180.0
HKD1_k127_2643575_5 - - - - 0.000000000000000000000000002737 120.0
HKD1_k127_2643575_6 DNA-binding transcriptional activator of the SARP family - - - 0.00003461 57.0
HKD1_k127_265312_0 Peptidase S46 - - - 1.709e-280 887.0
HKD1_k127_265312_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 598.0
HKD1_k127_265312_10 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000000115 117.0
HKD1_k127_265312_11 Diacylglycerol kinase catalytic domain K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.00000000000000000003673 103.0
HKD1_k127_265312_12 Alternative locus ID - - - 0.0004889 52.0
HKD1_k127_265312_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 580.0
HKD1_k127_265312_3 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 355.0
HKD1_k127_265312_4 Mrr N-terminal domain K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 320.0
HKD1_k127_265312_5 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003123 290.0
HKD1_k127_265312_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000005039 231.0
HKD1_k127_265312_7 DinB family - - - 0.0000000000000000000000000000000000000000000007092 172.0
HKD1_k127_265312_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000001849 125.0
HKD1_k127_265312_9 sequence-specific DNA binding K07726 - - 0.0000000000000000000000000001308 118.0
HKD1_k127_2692251_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 414.0
HKD1_k127_2692251_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 352.0
HKD1_k127_2692251_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000001556 60.0
HKD1_k127_2718446_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 630.0
HKD1_k127_2718446_1 amino acid transport K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 420.0
HKD1_k127_2718446_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 335.0
HKD1_k127_276083_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 399.0
HKD1_k127_276083_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 359.0
HKD1_k127_276083_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 302.0
HKD1_k127_276083_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 301.0
HKD1_k127_276083_4 Copper homeostasis K06079 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0010810,GO:0016020,GO:0019867,GO:0030155,GO:0030312,GO:0030313,GO:0031975,GO:0042802,GO:0044462,GO:0044464,GO:0050789,GO:0065007,GO:0071944 - 0.00000000000000000000000000000000000000000000000009132 198.0
HKD1_k127_276083_5 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000006637 138.0
HKD1_k127_276083_6 Stage II sporulation protein K06381 - - 0.000000000000000000000000000001346 132.0
HKD1_k127_276083_7 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000000000006072 123.0
HKD1_k127_276083_8 PFAM aminotransferase class V - - - 0.0000000001911 65.0
HKD1_k127_276087_0 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 611.0
HKD1_k127_2948572_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000002746 253.0
HKD1_k127_2948572_1 Cytochrome c K02305,K07152 - - 0.000000001341 71.0
HKD1_k127_2953114_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 330.0
HKD1_k127_2953114_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 294.0
HKD1_k127_2953114_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000001802 245.0
HKD1_k127_2953114_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000007886 165.0
HKD1_k127_2953114_4 FecCD transport family K02015 - - 0.0000000000000000000000000000000002646 147.0
HKD1_k127_2953114_5 Predicted membrane protein (DUF2231) - - - 0.000000002774 66.0
HKD1_k127_2953114_6 Rubrerythrin - - - 0.00000003393 57.0
HKD1_k127_29596_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.704e-208 669.0
HKD1_k127_29596_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 364.0
HKD1_k127_29596_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 341.0
HKD1_k127_29596_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 294.0
HKD1_k127_29596_4 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000004627 217.0
HKD1_k127_29596_5 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000005353 158.0
HKD1_k127_29596_6 ABC transporter K02003 - - 0.000000000000000000003019 96.0
HKD1_k127_2965075_0 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 322.0
HKD1_k127_2965075_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 323.0
HKD1_k127_2965075_2 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 307.0
HKD1_k127_2965075_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000003429 248.0
HKD1_k127_2965075_4 (FHA) domain - - - 0.000000000005588 72.0
HKD1_k127_3032732_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 546.0
HKD1_k127_3032732_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 446.0
HKD1_k127_3032732_10 peptidase inhibitor activity - - - 0.000000000000000002739 98.0
HKD1_k127_3032732_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000003726 96.0
HKD1_k127_3032732_13 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000005273 83.0
HKD1_k127_3032732_15 Integrase core domain K07497 - - 0.00000000121 70.0
HKD1_k127_3032732_16 Domain of unknown function (DUF4339) - - - 0.00000001906 63.0
HKD1_k127_3032732_17 Tetratricopeptide repeat - - - 0.000001543 62.0
HKD1_k127_3032732_18 - - - - 0.000009161 49.0
HKD1_k127_3032732_19 Cytochrome c - - - 0.0009325 46.0
HKD1_k127_3032732_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 450.0
HKD1_k127_3032732_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 422.0
HKD1_k127_3032732_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 318.0
HKD1_k127_3032732_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 309.0
HKD1_k127_3032732_6 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
HKD1_k127_3032732_7 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000001492 233.0
HKD1_k127_3032732_8 Predicted membrane protein (DUF2142) - - - 0.00000000000000000000000000000000000000000000000003863 198.0
HKD1_k127_3032732_9 TM2 domain - - - 0.00000000000000000000001816 107.0
HKD1_k127_3130135_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.387e-228 716.0
HKD1_k127_3130135_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.167e-216 694.0
HKD1_k127_3130135_10 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000004157 159.0
HKD1_k127_3130135_11 ACT domain K09707 - - 0.00000000000000000000000000000007456 128.0
HKD1_k127_3130135_12 Psort location CytoplasmicMembrane, score - - - 0.0000003567 61.0
HKD1_k127_3130135_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 560.0
HKD1_k127_3130135_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 488.0
HKD1_k127_3130135_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 460.0
HKD1_k127_3130135_5 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 377.0
HKD1_k127_3130135_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 360.0
HKD1_k127_3130135_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000007615 215.0
HKD1_k127_3130135_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000186 205.0
HKD1_k127_3130135_9 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000002879 187.0
HKD1_k127_3139147_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000001136 251.0
HKD1_k127_3139147_1 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000003053 212.0
HKD1_k127_3139147_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000005059 152.0
HKD1_k127_3139147_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000001972 86.0
HKD1_k127_3139147_4 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.0000000000007666 83.0
HKD1_k127_3169337_0 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 344.0
HKD1_k127_3169337_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000001626 209.0
HKD1_k127_3169337_2 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000604 174.0
HKD1_k127_3239097_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 393.0
HKD1_k127_3239097_1 ABC transporter C-terminal domain K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 393.0
HKD1_k127_3239097_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 323.0
HKD1_k127_3239097_3 methyltransferase activity - - - 0.00000000000000000000000000000000000000001407 160.0
HKD1_k127_3248579_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 509.0
HKD1_k127_3248579_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001064 282.0
HKD1_k127_3248579_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000002275 230.0
HKD1_k127_3248579_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000004275 230.0
HKD1_k127_3248579_4 TonB dependent receptor K02014,K16087 - - 0.00000000000000000000000000004368 135.0
HKD1_k127_3248579_5 TonB-dependent receptor plug - - - 0.000000000000000000000001924 120.0
HKD1_k127_3249580_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1805.0
HKD1_k127_3249580_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 599.0
HKD1_k127_3261943_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 6.903e-200 635.0
HKD1_k127_3261943_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 424.0
HKD1_k127_3261943_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 384.0
HKD1_k127_3261943_3 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 346.0
HKD1_k127_3261943_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000004007 251.0
HKD1_k127_3261943_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000002905 78.0
HKD1_k127_3261943_6 nucleotide catabolic process K01119 - 3.1.3.6,3.1.4.16 0.0000000002525 73.0
HKD1_k127_3261943_7 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.0000001238 64.0
HKD1_k127_3264349_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 619.0
HKD1_k127_3264349_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 406.0
HKD1_k127_3264349_2 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000001121 249.0
HKD1_k127_3264349_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000009051 177.0
HKD1_k127_3264349_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000008649 138.0
HKD1_k127_3264349_5 Outer membrane efflux protein K15725 - - 0.00000000000000000000000001794 124.0
HKD1_k127_3277868_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 441.0
HKD1_k127_3277868_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 444.0
HKD1_k127_3277868_2 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 433.0
HKD1_k127_3277868_3 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 374.0
HKD1_k127_3277868_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000006465 179.0
HKD1_k127_3327076_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 392.0
HKD1_k127_3327076_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001534 184.0
HKD1_k127_3327076_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000001326 147.0
HKD1_k127_3327076_3 AI-2E family transporter - - - 0.0000000000000000000000000000005448 137.0
HKD1_k127_3327076_4 phosphorelay signal transduction system - - - 0.00000000000000000000000009659 120.0
HKD1_k127_3327076_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000004322 108.0
HKD1_k127_3327076_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000008102 101.0
HKD1_k127_3327076_7 chlorophyll binding - - - 0.00001827 57.0
HKD1_k127_3327076_8 cell division ATP-binding protein K09812 - - 0.0002061 44.0
HKD1_k127_333220_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
HKD1_k127_333220_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 376.0
HKD1_k127_333220_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 337.0
HKD1_k127_333220_3 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003496 276.0
HKD1_k127_333220_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001358 239.0
HKD1_k127_333220_5 response to stress - - - 0.000000000000000007698 98.0
HKD1_k127_333220_6 Redoxin - - - 0.00000006584 62.0
HKD1_k127_333220_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0006922 52.0
HKD1_k127_3342672_0 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002321 250.0
HKD1_k127_3342672_1 PFAM Ion transport 2 domain protein - - - 0.000000000000000000000000000000000002687 146.0
HKD1_k127_3342672_2 peptidase activity - - - 0.000000000588 71.0
HKD1_k127_3342672_3 Domain of unknown function (DUF4282) - - - 0.0004241 52.0
HKD1_k127_3349163_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 317.0
HKD1_k127_3349163_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 307.0
HKD1_k127_3349163_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000001471 244.0
HKD1_k127_3349163_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000002944 222.0
HKD1_k127_3349163_4 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000003179 170.0
HKD1_k127_3349163_5 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000002794 135.0
HKD1_k127_3350123_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 573.0
HKD1_k127_3350123_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 374.0
HKD1_k127_3350123_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
HKD1_k127_3350123_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002232 267.0
HKD1_k127_3350123_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000001718 203.0
HKD1_k127_3350123_6 Belongs to the UPF0235 family K09131 - - 0.00008873 55.0
HKD1_k127_3398072_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.643e-288 900.0
HKD1_k127_3398072_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
HKD1_k127_3398072_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003971 294.0
HKD1_k127_3398072_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000006685 238.0
HKD1_k127_3398072_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000001098 222.0
HKD1_k127_3427067_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 414.0
HKD1_k127_3427067_1 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 368.0
HKD1_k127_3427067_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000008521 139.0
HKD1_k127_3427067_3 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000005209 107.0
HKD1_k127_3427067_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000001425 100.0
HKD1_k127_3434624_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 3.18e-233 739.0
HKD1_k127_3434624_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 8.504e-202 638.0
HKD1_k127_3434624_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 509.0
HKD1_k127_3434624_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 287.0
HKD1_k127_3434624_4 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003788 272.0
HKD1_k127_3434624_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
HKD1_k127_3434624_6 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000729 181.0
HKD1_k127_3485224_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000621 183.0
HKD1_k127_3485224_1 - - - - 0.000001311 56.0
HKD1_k127_3666227_0 ABC transporter transmembrane K11085 - - 3.514e-249 802.0
HKD1_k127_3666227_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 501.0
HKD1_k127_3666227_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 351.0
HKD1_k127_3666227_3 saccharopine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 319.0
HKD1_k127_3666227_6 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000174 93.0
HKD1_k127_3750516_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 410.0
HKD1_k127_3750516_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000006296 218.0
HKD1_k127_3750516_2 NAD metabolism ATPase kinase - - - 0.0002317 53.0
HKD1_k127_375310_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.769e-238 762.0
HKD1_k127_375310_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.144e-209 674.0
HKD1_k127_375310_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000001418 235.0
HKD1_k127_375310_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000002294 225.0
HKD1_k127_375310_5 DinB family - - - 0.00000000000000000000000000000000000000000000000004519 183.0
HKD1_k127_375310_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001503 123.0
HKD1_k127_375310_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000002094 116.0
HKD1_k127_375310_8 Protein of unknown function (DUF503) K09764 - - 0.00000000001368 70.0
HKD1_k127_375310_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00006344 56.0
HKD1_k127_3894251_0 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000001994 105.0
HKD1_k127_3894251_1 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000001936 100.0
HKD1_k127_3894251_2 General Secretion Pathway protein K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000002973 55.0
HKD1_k127_3905797_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 3.344e-277 873.0
HKD1_k127_3905797_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 9.243e-233 729.0
HKD1_k127_3905797_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
HKD1_k127_3905797_11 Homocysteine S-methyltransferase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.0000000000000000000000000000000000000000000000000000000008719 216.0
HKD1_k127_3905797_12 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000001984 193.0
HKD1_k127_3905797_13 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000001597 189.0
HKD1_k127_3905797_15 PFAM Vitamin B12 dependent methionine synthase activation region - - - 0.000000000009713 77.0
HKD1_k127_3905797_17 cellulase activity - - - 0.00000001538 69.0
HKD1_k127_3905797_18 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0007053 52.0
HKD1_k127_3905797_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 596.0
HKD1_k127_3905797_3 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 552.0
HKD1_k127_3905797_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 485.0
HKD1_k127_3905797_5 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 487.0
HKD1_k127_3905797_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 441.0
HKD1_k127_3905797_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 417.0
HKD1_k127_3905797_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 389.0
HKD1_k127_3905797_9 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006689 239.0
HKD1_k127_3919096_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 336.0
HKD1_k127_3919096_1 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005543 273.0
HKD1_k127_3919096_2 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000004896 211.0
HKD1_k127_3919096_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000002485 174.0
HKD1_k127_3919096_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000001392 164.0
HKD1_k127_3919096_5 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000004442 134.0
HKD1_k127_3919096_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000108 121.0
HKD1_k127_3928879_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003668 266.0
HKD1_k127_3928879_1 Product type r regulator - - - 0.000000000000000000000000000000000000000000000000000000003102 214.0
HKD1_k127_3928879_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000555 168.0
HKD1_k127_3928879_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000001009 164.0
HKD1_k127_3928879_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000001873 145.0
HKD1_k127_3928879_5 - - - - 0.000000000000000000000000000000000191 141.0
HKD1_k127_3928879_6 response regulator K07685 - - 0.0000000000003514 77.0
HKD1_k127_3966522_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 581.0
HKD1_k127_3966522_1 3-deoxy-7-phosphoheptulonate synthase activity K00661,K03856,K04092,K04093,K04516,K04518,K14170,K14187 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,2.5.1.54,4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 475.0
HKD1_k127_3966522_10 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000002362 162.0
HKD1_k127_3966522_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000001175 139.0
HKD1_k127_3966522_12 - - - - 0.0000000000000000000000000000000006176 151.0
HKD1_k127_3966522_13 response regulator, receiver - - - 0.00000000000000000000000000000006919 128.0
HKD1_k127_3966522_14 Cytidylate kinase-like family - - - 0.00000000000000000000000001018 123.0
HKD1_k127_3966522_15 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000002304 124.0
HKD1_k127_3966522_16 Putative DNA-binding domain - - - 0.0000000000000000000000009308 115.0
HKD1_k127_3966522_17 cell septum assembly - - - 0.00000000000000000000004019 110.0
HKD1_k127_3966522_18 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000001498 112.0
HKD1_k127_3966522_19 Alpha beta hydrolase - - - 0.000000000000000000005219 107.0
HKD1_k127_3966522_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 440.0
HKD1_k127_3966522_20 protein mobile region - - - 0.0000000000000000173 96.0
HKD1_k127_3966522_21 - - - - 0.00000000004069 75.0
HKD1_k127_3966522_22 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000009483 63.0
HKD1_k127_3966522_23 Sporulation and spore germination K06298 - - 0.00001174 56.0
HKD1_k127_3966522_3 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 364.0
HKD1_k127_3966522_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 354.0
HKD1_k127_3966522_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006708 276.0
HKD1_k127_3966522_6 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009627 268.0
HKD1_k127_3966522_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000002452 253.0
HKD1_k127_3966522_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002491 274.0
HKD1_k127_3966522_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002161 196.0
HKD1_k127_4030944_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000004902 248.0
HKD1_k127_4030944_1 helix_turn_helix, Lux Regulon - - - 0.0000000003478 70.0
HKD1_k127_4030944_2 FHA domain - - - 0.0001668 54.0
HKD1_k127_4032906_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 390.0
HKD1_k127_4032906_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 350.0
HKD1_k127_4032906_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009457 264.0
HKD1_k127_4032906_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000006595 137.0
HKD1_k127_4032906_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000003378 136.0
HKD1_k127_4032906_5 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000005693 98.0
HKD1_k127_4032906_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000001645 78.0
HKD1_k127_4032906_7 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000001517 85.0
HKD1_k127_4032906_8 mttA/Hcf106 family K03116 - - 0.000000000001744 72.0
HKD1_k127_4071871_0 topoisomerase K02469 - 5.99.1.3 1.909e-270 853.0
HKD1_k127_4071871_1 gluconolactonase activity - - - 3.294e-223 733.0
HKD1_k127_4071871_10 C-terminal domain of CHU protein family - - - 0.00000000000000001675 98.0
HKD1_k127_4071871_11 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000003951 64.0
HKD1_k127_4071871_12 Belongs to the peptidase S8 family - - - 0.000000002285 72.0
HKD1_k127_4071871_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 544.0
HKD1_k127_4071871_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 355.0
HKD1_k127_4071871_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 351.0
HKD1_k127_4071871_5 - - - - 0.0000000000000000000000000000000000000000000000002514 198.0
HKD1_k127_4071871_6 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001366 164.0
HKD1_k127_4071871_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000001031 155.0
HKD1_k127_4071871_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000001172 166.0
HKD1_k127_4071871_9 peptidase activity - - - 0.000000000000000000000000000001643 136.0
HKD1_k127_4105150_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 581.0
HKD1_k127_4105150_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000001893 214.0
HKD1_k127_4105150_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000002165 107.0
HKD1_k127_4105150_3 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000004385 89.0
HKD1_k127_4105150_4 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.0000000000001936 78.0
HKD1_k127_4105150_5 Protein of unknown function (DUF465) - - - 0.00003383 49.0
HKD1_k127_4136073_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 441.0
HKD1_k127_4136073_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 378.0
HKD1_k127_4136073_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000001579 215.0
HKD1_k127_4136073_3 Bacterial membrane protein, YfhO - - - 0.000000000000004472 89.0
HKD1_k127_4136073_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000005854 78.0
HKD1_k127_4136073_5 Response regulator receiver domain - - - 0.0000000389 66.0
HKD1_k127_4140655_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 606.0
HKD1_k127_4140655_1 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 500.0
HKD1_k127_4140655_2 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 358.0
HKD1_k127_4140655_3 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 332.0
HKD1_k127_4140655_4 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000005014 221.0
HKD1_k127_4140655_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000004114 174.0
HKD1_k127_4140655_6 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000007279 134.0
HKD1_k127_4232659_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 340.0
HKD1_k127_4232659_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008289 296.0
HKD1_k127_4232659_10 - - - - 0.00000002463 58.0
HKD1_k127_4232659_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000003233 223.0
HKD1_k127_4232659_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006959 179.0
HKD1_k127_4232659_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000003065 177.0
HKD1_k127_4232659_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000599 181.0
HKD1_k127_4232659_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000004115 164.0
HKD1_k127_4232659_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000009279 166.0
HKD1_k127_4232659_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000003053 151.0
HKD1_k127_4232659_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000001126 142.0
HKD1_k127_4234759_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 2.618e-200 644.0
HKD1_k127_4234759_1 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000005556 102.0
HKD1_k127_4234759_2 - - - - 0.0000000000000004263 88.0
HKD1_k127_4234759_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000005595 81.0
HKD1_k127_4234759_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000003439 76.0
HKD1_k127_4234759_5 - - - - 0.00000002113 64.0
HKD1_k127_4240767_0 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 586.0
HKD1_k127_4240767_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 475.0
HKD1_k127_4240767_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000006161 153.0
HKD1_k127_4240767_11 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000009446 151.0
HKD1_k127_4240767_12 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000008496 119.0
HKD1_k127_4240767_13 RNA-binding protein containing a PIN domain K06962 - - 0.0000001645 59.0
HKD1_k127_4240767_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
HKD1_k127_4240767_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 328.0
HKD1_k127_4240767_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000001164 235.0
HKD1_k127_4240767_5 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000163 202.0
HKD1_k127_4240767_6 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000114 171.0
HKD1_k127_4240767_7 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000002318 186.0
HKD1_k127_4240767_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000008368 184.0
HKD1_k127_4240767_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000001822 171.0
HKD1_k127_4258748_0 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 299.0
HKD1_k127_4361117_0 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 354.0
HKD1_k127_4361117_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 333.0
HKD1_k127_4361117_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 305.0
HKD1_k127_4361117_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000007195 204.0
HKD1_k127_4370889_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 305.0
HKD1_k127_4370889_1 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000002596 196.0
HKD1_k127_4370889_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000001965 190.0
HKD1_k127_4370889_3 PFAM ABC-3 protein K09816,K09819,K19976 - - 0.000000000000000000000000000000000000000001793 175.0
HKD1_k127_4370889_4 ATPases associated with a variety of cellular activities K09820,K11603,K11710,K19973 - 3.6.3.35 0.0000000000000000000000000000003663 137.0
HKD1_k127_4370889_5 Psort location Cytoplasmic, score 8.96 - - - 0.0001802 53.0
HKD1_k127_4380155_0 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 493.0
HKD1_k127_4380155_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 476.0
HKD1_k127_4380155_10 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 300.0
HKD1_k127_4380155_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 301.0
HKD1_k127_4380155_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 293.0
HKD1_k127_4380155_13 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006967 309.0
HKD1_k127_4380155_14 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000006014 258.0
HKD1_k127_4380155_15 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
HKD1_k127_4380155_16 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000004498 243.0
HKD1_k127_4380155_17 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000002495 235.0
HKD1_k127_4380155_18 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000002248 192.0
HKD1_k127_4380155_19 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000003377 151.0
HKD1_k127_4380155_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 492.0
HKD1_k127_4380155_20 Amino acid permease - - - 0.0000000000000000000000000000005066 125.0
HKD1_k127_4380155_21 PFAM sulfatase - - - 0.00000000000000000000000000002512 136.0
HKD1_k127_4380155_22 Membrane - - - 0.00000000000000000000006967 116.0
HKD1_k127_4380155_23 Membrane - - - 0.00000000000000000003127 107.0
HKD1_k127_4380155_24 ABC-type transport system involved in cytochrome c biogenesis, permease component K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.0000000000685 72.0
HKD1_k127_4380155_25 ABC-type molybdate transport system periplasmic component K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000003511 69.0
HKD1_k127_4380155_26 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000003642 61.0
HKD1_k127_4380155_27 Lanthionine synthetase C family protein - - - 0.00006586 55.0
HKD1_k127_4380155_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 490.0
HKD1_k127_4380155_4 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 436.0
HKD1_k127_4380155_5 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 430.0
HKD1_k127_4380155_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 422.0
HKD1_k127_4380155_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 397.0
HKD1_k127_4380155_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 377.0
HKD1_k127_4380155_9 uroporphyrinogen decarboxylase activity K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 306.0
HKD1_k127_4397405_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 2.675e-282 902.0
HKD1_k127_4397405_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 2.498e-209 674.0
HKD1_k127_4397405_10 CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000108 280.0
HKD1_k127_4397405_11 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001555 286.0
HKD1_k127_4397405_12 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002391 265.0
HKD1_k127_4397405_13 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006804 260.0
HKD1_k127_4397405_14 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000002924 184.0
HKD1_k127_4397405_15 PAS sensor protein - - - 0.000000000000000000000000000000000000000000004459 184.0
HKD1_k127_4397405_16 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000002515 149.0
HKD1_k127_4397405_17 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000001274 134.0
HKD1_k127_4397405_18 Alpha/beta hydrolase family - - - 0.0000000000000000000000000003768 123.0
HKD1_k127_4397405_19 Phosphate-selective porin O and P - - - 0.00000000000000000000000581 119.0
HKD1_k127_4397405_2 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 550.0
HKD1_k127_4397405_20 Belongs to the universal stress protein A family - - - 0.0000000000000000008303 93.0
HKD1_k127_4397405_21 MarR family - - - 0.000009603 54.0
HKD1_k127_4397405_3 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 470.0
HKD1_k127_4397405_4 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 392.0
HKD1_k127_4397405_5 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 373.0
HKD1_k127_4397405_6 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 318.0
HKD1_k127_4397405_7 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 292.0
HKD1_k127_4397405_8 Acyl-CoA dehydrogenase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 294.0
HKD1_k127_4397405_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000858 293.0
HKD1_k127_441223_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 358.0
HKD1_k127_441223_1 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 324.0
HKD1_k127_4417392_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 349.0
HKD1_k127_4417392_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000009304 169.0
HKD1_k127_4417392_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000004898 61.0
HKD1_k127_4417392_3 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000001497 53.0
HKD1_k127_4453112_0 GMC oxidoreductase K03333 - 1.1.3.6 8.76e-228 717.0
HKD1_k127_4453112_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.565e-199 625.0
HKD1_k127_4453112_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 367.0
HKD1_k127_4453112_3 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001403 267.0
HKD1_k127_4453112_4 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000001132 180.0
HKD1_k127_4453112_5 Putative adhesin - - - 0.0000000000002046 82.0
HKD1_k127_4453112_6 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000008316 71.0
HKD1_k127_4458706_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1513.0
HKD1_k127_4458706_1 cellulose binding - - - 3.238e-224 701.0
HKD1_k127_4458706_10 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 318.0
HKD1_k127_4458706_11 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 317.0
HKD1_k127_4458706_12 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001708 224.0
HKD1_k127_4458706_13 - - - - 0.0000000000000000000000000000000000000000000000001744 186.0
HKD1_k127_4458706_14 COG1174 ABC-type proline glycine betaine transport systems permease component K05845,K05846 - - 0.0000000000000000000000000000000000000000000005177 184.0
HKD1_k127_4458706_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000000002465 154.0
HKD1_k127_4458706_16 TonB dependent receptor K02014 - - 0.00000000000000000000000000008105 136.0
HKD1_k127_4458706_17 Protein of unknown function (DUF1634) - - - 0.0000000000000000007594 100.0
HKD1_k127_4458706_18 PFAM PKD domain containing protein - - - 0.00000000003025 78.0
HKD1_k127_4458706_19 Helicase conserved C-terminal domain - - - 0.00001083 57.0
HKD1_k127_4458706_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 474.0
HKD1_k127_4458706_20 lactoylglutathione lyase activity - - - 0.0001185 49.0
HKD1_k127_4458706_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 434.0
HKD1_k127_4458706_4 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 455.0
HKD1_k127_4458706_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HKD1_k127_4458706_6 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
HKD1_k127_4458706_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 321.0
HKD1_k127_4458706_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 319.0
HKD1_k127_4458706_9 SMART ATPase, AAA type, core K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 308.0
HKD1_k127_4469307_0 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 506.0
HKD1_k127_4469307_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 484.0
HKD1_k127_4469307_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 484.0
HKD1_k127_4469307_3 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 405.0
HKD1_k127_4469307_4 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000001163 217.0
HKD1_k127_4469307_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000002374 210.0
HKD1_k127_4469307_6 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000004683 200.0
HKD1_k127_4469307_7 Peptidase C26 K07010 - - 0.00000000000000000000000000000000003782 152.0
HKD1_k127_4469307_8 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000001182 109.0
HKD1_k127_4469307_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000007883 66.0
HKD1_k127_4499528_0 Sortilin, neurotensin receptor 3, - - - 0.0 1139.0
HKD1_k127_4499528_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 439.0
HKD1_k127_4499528_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 402.0
HKD1_k127_4499528_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 402.0
HKD1_k127_4499528_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 312.0
HKD1_k127_4499528_5 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000135 255.0
HKD1_k127_4499528_6 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
HKD1_k127_4499528_7 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000001653 159.0
HKD1_k127_4508479_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 565.0
HKD1_k127_4508479_1 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 378.0
HKD1_k127_4508479_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005258 298.0
HKD1_k127_4508479_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000006133 212.0
HKD1_k127_4508479_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000001614 192.0
HKD1_k127_4508479_5 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000004447 149.0
HKD1_k127_4508479_6 A G-specific K03575 - - 0.00000000000002688 74.0
HKD1_k127_4508479_7 Methionine biosynthesis protein MetW - - - 0.000003239 59.0
HKD1_k127_4508479_8 Psort location Cytoplasmic, score 8.96 - - - 0.00007286 54.0
HKD1_k127_4508479_9 PFAM CHAD domain containing protein - - - 0.0001817 53.0
HKD1_k127_4700395_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 394.0
HKD1_k127_4700395_1 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 360.0
HKD1_k127_4700395_2 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000009011 238.0
HKD1_k127_4700395_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000008345 205.0
HKD1_k127_4700395_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000003049 171.0
HKD1_k127_4700395_5 lactate metabolic process - - - 0.000000000000000000000000000000000003856 144.0
HKD1_k127_4700395_6 phosphohistidine phosphatase K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000002714 93.0
HKD1_k127_4700395_7 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000003397 63.0
HKD1_k127_4731415_0 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 587.0
HKD1_k127_4731415_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 458.0
HKD1_k127_4731415_10 DinB family - - - 0.000000000000000000000000000000000000697 148.0
HKD1_k127_4731415_11 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000009645 137.0
HKD1_k127_4731415_12 acyl-coa-binding protein - - - 0.000000000000000000000001104 106.0
HKD1_k127_4731415_13 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000001069 110.0
HKD1_k127_4731415_14 Belongs to the UPF0312 family - - - 0.000000004986 67.0
HKD1_k127_4731415_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 443.0
HKD1_k127_4731415_3 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 401.0
HKD1_k127_4731415_4 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 325.0
HKD1_k127_4731415_5 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000008705 213.0
HKD1_k127_4731415_6 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000001444 200.0
HKD1_k127_4731415_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000002637 205.0
HKD1_k127_4731415_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000003854 211.0
HKD1_k127_4759227_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 8.034e-256 816.0
HKD1_k127_4759227_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 586.0
HKD1_k127_4759227_10 - - - - 0.0000000000000000000000000000000000000000000000000000003785 200.0
HKD1_k127_4759227_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001089 194.0
HKD1_k127_4759227_12 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001235 190.0
HKD1_k127_4759227_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000009463 181.0
HKD1_k127_4759227_14 - - - - 0.0000000000000000000000000000000000000000007776 169.0
HKD1_k127_4759227_15 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000000000000000000000000000002708 148.0
HKD1_k127_4759227_16 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000007578 132.0
HKD1_k127_4759227_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000001572 117.0
HKD1_k127_4759227_18 - - - - 0.000000000000000000000328 111.0
HKD1_k127_4759227_19 domain, Protein - - - 0.0000000000003227 83.0
HKD1_k127_4759227_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 569.0
HKD1_k127_4759227_20 - - - - 0.000007923 49.0
HKD1_k127_4759227_21 metallopeptidase activity - - - 0.00001984 53.0
HKD1_k127_4759227_3 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 525.0
HKD1_k127_4759227_4 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 508.0
HKD1_k127_4759227_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 358.0
HKD1_k127_4759227_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 329.0
HKD1_k127_4759227_7 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 313.0
HKD1_k127_4759227_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003613 300.0
HKD1_k127_4759227_9 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002122 257.0
HKD1_k127_4772889_0 Sucrose synthase K00695 - 2.4.1.13 1.3e-322 1014.0
HKD1_k127_4772889_1 Glycosyl transferase, group 1 K00696 - 2.4.1.14 9.401e-282 898.0
HKD1_k127_4772889_10 CBS domain - - - 0.000000000000000000005705 98.0
HKD1_k127_4772889_11 Mannosyl-3-phosphoglycerate phosphatase family K07026 - 3.1.3.70 0.000000000000000000008724 102.0
HKD1_k127_4772889_12 transmembrane transport - - - 0.0000000000000000001643 97.0
HKD1_k127_4772889_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.054e-225 709.0
HKD1_k127_4772889_3 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 590.0
HKD1_k127_4772889_4 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 431.0
HKD1_k127_4772889_5 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006935 253.0
HKD1_k127_4772889_6 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000001919 179.0
HKD1_k127_4772889_7 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000001218 170.0
HKD1_k127_4772889_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000001288 150.0
HKD1_k127_4772889_9 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000000003337 150.0
HKD1_k127_4900647_0 Transport of potassium into the cell K03549 - - 2.528e-209 679.0
HKD1_k127_4900647_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 589.0
HKD1_k127_4900647_10 Belongs to the universal stress protein A family - - - 0.0000000000000003358 88.0
HKD1_k127_4900647_11 Psort location Cytoplasmic, score - - - 0.0000000000000009623 90.0
HKD1_k127_4900647_12 Protein of unknown function (DUF2723) - - - 0.000000003189 70.0
HKD1_k127_4900647_13 Bacterial membrane protein YfhO - - - 0.00000001234 66.0
HKD1_k127_4900647_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 354.0
HKD1_k127_4900647_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 331.0
HKD1_k127_4900647_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 316.0
HKD1_k127_4900647_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 270.0
HKD1_k127_4900647_6 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
HKD1_k127_4900647_7 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000004709 232.0
HKD1_k127_4900647_8 - - - - 0.0000000000000000000000000000001133 141.0
HKD1_k127_4900647_9 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000008376 131.0
HKD1_k127_4927745_0 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 416.0
HKD1_k127_4927745_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573,K03183,K07003 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.163,2.1.1.201,2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 352.0
HKD1_k127_4927745_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000002479 138.0
HKD1_k127_4927745_11 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000002049 142.0
HKD1_k127_4927745_12 protein kinase activity - - - 0.00000000000000000000000000001863 132.0
HKD1_k127_4927745_13 Forkhead associated domain - - - 0.0000000000000007376 91.0
HKD1_k127_4927745_14 2Fe-2S -binding domain - - - 0.00000005233 59.0
HKD1_k127_4927745_15 Protein of unknown function, DUF255 - - - 0.0005382 51.0
HKD1_k127_4927745_2 - - - - 0.0000000000000000000000000000000000000000000000000000000005583 211.0
HKD1_k127_4927745_3 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000184 218.0
HKD1_k127_4927745_4 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000005501 202.0
HKD1_k127_4927745_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000004397 186.0
HKD1_k127_4927745_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000004071 173.0
HKD1_k127_4927745_7 - - - - 0.00000000000000000000000000000000000000006506 167.0
HKD1_k127_4927745_8 amino acid - - - 0.000000000000000000000000000000000000008018 150.0
HKD1_k127_4927745_9 Lipopolysaccharide kinase (Kdo/WaaP) family K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000002377 154.0
HKD1_k127_4960358_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000787 315.0
HKD1_k127_4960358_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001255 257.0
HKD1_k127_4960358_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000002647 166.0
HKD1_k127_4960358_3 domain, Protein - - - 0.0000000000000000000000000002957 133.0
HKD1_k127_4960358_4 HD domain - - - 0.000000000000000000000001058 117.0
HKD1_k127_4960358_5 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000003241 85.0
HKD1_k127_5021374_0 4Fe-4S single cluster domain K06937 - - 3.239e-240 781.0
HKD1_k127_5021374_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
HKD1_k127_5021374_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000002987 186.0
HKD1_k127_5021374_11 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000001979 153.0
HKD1_k127_5021374_12 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000002425 135.0
HKD1_k127_5021374_13 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000001254 126.0
HKD1_k127_5021374_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000001888 115.0
HKD1_k127_5021374_15 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000007374 113.0
HKD1_k127_5021374_16 PFAM PASTA domain K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.000000000007307 74.0
HKD1_k127_5021374_17 mttA/Hcf106 family K03116 - - 0.0000000000503 70.0
HKD1_k127_5021374_18 PFAM helix-turn-helix, Fis-type - - - 0.0000005297 56.0
HKD1_k127_5021374_19 protein containing LysM domain - - - 0.0000008761 60.0
HKD1_k127_5021374_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 385.0
HKD1_k127_5021374_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002156 293.0
HKD1_k127_5021374_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 282.0
HKD1_k127_5021374_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 272.0
HKD1_k127_5021374_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001675 285.0
HKD1_k127_5021374_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000001219 228.0
HKD1_k127_5021374_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
HKD1_k127_5021374_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000001824 185.0
HKD1_k127_5042106_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 495.0
HKD1_k127_5042106_1 Protein of unknown function (DUF1579) - - - 0.0000000000004695 74.0
HKD1_k127_5064079_0 Peptidase family M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 607.0
HKD1_k127_5064079_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 438.0
HKD1_k127_5064079_10 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000003254 199.0
HKD1_k127_5064079_11 FR47-like protein - - - 0.00000000000000000000000000000000000000000002166 177.0
HKD1_k127_5064079_12 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000004702 162.0
HKD1_k127_5064079_13 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000001169 139.0
HKD1_k127_5064079_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.00000000000000000000000003413 124.0
HKD1_k127_5064079_15 Zincin-like metallopeptidase - - - 0.00000000000000000000002184 112.0
HKD1_k127_5064079_16 Domain of unknown function (DUF4410) - - - 0.000000000004009 75.0
HKD1_k127_5064079_17 Mycolic acid cyclopropane synthetase - - - 0.0000000747 64.0
HKD1_k127_5064079_18 trisaccharide binding K03556 - - 0.000004515 57.0
HKD1_k127_5064079_19 Heavy-metal resistance - - - 0.0006493 49.0
HKD1_k127_5064079_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 422.0
HKD1_k127_5064079_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 359.0
HKD1_k127_5064079_4 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
HKD1_k127_5064079_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 320.0
HKD1_k127_5064079_6 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 308.0
HKD1_k127_5064079_7 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 300.0
HKD1_k127_5064079_8 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000966 304.0
HKD1_k127_5064079_9 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000001538 238.0
HKD1_k127_5067984_0 Oligopeptide transporter OPT - - - 1.011e-227 726.0
HKD1_k127_5067984_1 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 300.0
HKD1_k127_5067984_2 Domain of unknown function (DUF3883) - - - 0.000000000000000000000000008245 115.0
HKD1_k127_5067984_3 - - - - 0.000000001186 70.0
HKD1_k127_5115385_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 443.0
HKD1_k127_5115385_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 329.0
HKD1_k127_5115385_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000008633 263.0
HKD1_k127_5115385_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
HKD1_k127_5115385_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000006243 200.0
HKD1_k127_5115385_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000001144 202.0
HKD1_k127_5115385_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000002469 169.0
HKD1_k127_5115702_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.573e-204 649.0
HKD1_k127_5115702_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 497.0
HKD1_k127_5115702_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 453.0
HKD1_k127_5115702_3 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 396.0
HKD1_k127_5115702_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000004543 226.0
HKD1_k127_5115702_5 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000003793 156.0
HKD1_k127_5115702_6 CHAP domain - - - 0.00000002218 63.0
HKD1_k127_5115702_7 - - - - 0.0003789 53.0
HKD1_k127_5145125_0 Amidohydrolase family K01443 - 3.5.1.25 1.953e-219 719.0
HKD1_k127_5145125_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 373.0
HKD1_k127_5145125_2 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000001716 160.0
HKD1_k127_5145125_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000001001 151.0
HKD1_k127_5145125_4 Transcription elongation factor, N-terminal - - - 0.0000000000000000000000001277 124.0
HKD1_k127_5147276_0 AcrB/AcrD/AcrF family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 336.0
HKD1_k127_5147276_1 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 353.0
HKD1_k127_5147276_2 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000001066 203.0
HKD1_k127_5147276_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000001749 188.0
HKD1_k127_5147276_4 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000004332 192.0
HKD1_k127_5147276_5 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000004795 181.0
HKD1_k127_5147276_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000959 123.0
HKD1_k127_5147276_7 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000642 82.0
HKD1_k127_5147276_8 protein secretion K03116 GO:0008150,GO:0040007 - 0.0000000000001351 73.0
HKD1_k127_5147276_9 EamA-like transporter family - - - 0.000000000002577 78.0
HKD1_k127_5149453_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 557.0
HKD1_k127_5149453_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 519.0
HKD1_k127_5149453_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 406.0
HKD1_k127_5149453_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000435 236.0
HKD1_k127_5149453_4 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000001326 179.0
HKD1_k127_5149453_5 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000001276 175.0
HKD1_k127_5149453_6 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000005606 182.0
HKD1_k127_5149453_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000002369 57.0
HKD1_k127_5149453_9 tigrfam pep-cterm - - - 0.000488 48.0
HKD1_k127_5208789_0 Sortilin, neurotensin receptor 3, - - - 0.0 1241.0
HKD1_k127_5208789_1 PFAM BNR Asp-box repeat - - - 1.582e-266 860.0
HKD1_k127_5208789_10 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003742 290.0
HKD1_k127_5208789_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 244.0
HKD1_k127_5208789_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000003368 223.0
HKD1_k127_5208789_13 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000001758 156.0
HKD1_k127_5208789_14 DinB family - - - 0.000000000000000000000000000000001519 142.0
HKD1_k127_5208789_2 Dehydratase family K01687 - 4.2.1.9 2.55e-225 711.0
HKD1_k127_5208789_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.678e-211 670.0
HKD1_k127_5208789_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 520.0
HKD1_k127_5208789_5 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 490.0
HKD1_k127_5208789_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 430.0
HKD1_k127_5208789_7 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HKD1_k127_5208789_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 368.0
HKD1_k127_5208789_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 351.0
HKD1_k127_5234790_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000001545 200.0
HKD1_k127_5234790_1 Arginine repressor, DNA binding domain K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000001939 97.0
HKD1_k127_5234790_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000001319 61.0
HKD1_k127_5239872_0 NeuB family K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 328.0
HKD1_k127_5239872_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000009509 141.0
HKD1_k127_5239872_2 - - - - 0.00000000000000000000000000000000008618 142.0
HKD1_k127_5239872_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000006442 135.0
HKD1_k127_5239872_4 PFAM membrane protein of K08972 - - 0.000000000000000000000000000002702 123.0
HKD1_k127_5239872_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000005738 117.0
HKD1_k127_5239872_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002363 61.0
HKD1_k127_5273075_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 575.0
HKD1_k127_5273075_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 362.0
HKD1_k127_5273075_2 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000203 295.0
HKD1_k127_5273075_3 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003229 260.0
HKD1_k127_5273075_4 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000004071 243.0
HKD1_k127_5273075_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000001024 203.0
HKD1_k127_5286808_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 403.0
HKD1_k127_5286808_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 313.0
HKD1_k127_5286808_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000005919 63.0
HKD1_k127_5286808_2 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003759 302.0
HKD1_k127_5286808_3 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000003096 237.0
HKD1_k127_5286808_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000001863 163.0
HKD1_k127_5286808_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000006043 119.0
HKD1_k127_5286808_6 PFAM pentapeptide repeat protein - - - 0.00000000000000000000000004692 126.0
HKD1_k127_5286808_7 EamA-like transporter family - - - 0.00000000000000000000000004806 119.0
HKD1_k127_5286808_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000009924 64.0
HKD1_k127_5286808_9 Domain of unknown function (DUF4340) - - - 0.0000005217 62.0
HKD1_k127_5315135_0 Proprotein convertase P-domain - - - 3.884e-274 863.0
HKD1_k127_5315135_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 534.0
HKD1_k127_5315135_10 response to oxidative stress - - - 0.00000000002155 76.0
HKD1_k127_5315135_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 457.0
HKD1_k127_5315135_3 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 438.0
HKD1_k127_5315135_4 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 360.0
HKD1_k127_5315135_5 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 336.0
HKD1_k127_5315135_6 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 334.0
HKD1_k127_5315135_7 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002567 276.0
HKD1_k127_5315135_8 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000003552 222.0
HKD1_k127_5315135_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000008902 121.0
HKD1_k127_5332224_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 515.0
HKD1_k127_5332224_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
HKD1_k127_5332224_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000006656 222.0
HKD1_k127_5332224_3 RNA recognition motif - - - 0.000000000000000000002524 102.0
HKD1_k127_5332224_4 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000519 98.0
HKD1_k127_538414_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000001162 247.0
HKD1_k127_538414_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001286 162.0
HKD1_k127_538414_2 - - - - 0.000000000000000000000000000000000004461 141.0
HKD1_k127_538414_3 - - - - 0.00000000000000000000000000004274 122.0
HKD1_k127_538414_4 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000001514 106.0
HKD1_k127_538414_5 metallopeptidase activity K01183,K01278,K03561,K12287 - 3.2.1.14,3.4.14.5 0.00000000000001655 87.0
HKD1_k127_538414_6 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - - 0.000003383 60.0
HKD1_k127_5411646_0 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 560.0
HKD1_k127_5411646_1 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 505.0
HKD1_k127_5473635_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.793e-303 942.0
HKD1_k127_5473635_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 2.872e-273 846.0
HKD1_k127_5473635_10 PFAM Response regulator receiver domain K07713 - - 0.00000003399 60.0
HKD1_k127_5473635_11 Histidine kinase - - - 0.0002344 52.0
HKD1_k127_5473635_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.845e-217 685.0
HKD1_k127_5473635_3 Cytochrome c - - - 6.489e-197 623.0
HKD1_k127_5473635_4 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 479.0
HKD1_k127_5473635_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001749 282.0
HKD1_k127_5473635_6 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000013 185.0
HKD1_k127_5473635_7 Cytochrome c - - - 0.00000000000000000000001233 107.0
HKD1_k127_5473635_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000002051 98.0
HKD1_k127_5473635_9 LuxR family transcriptional regulator K11618 - - 0.0000000004674 70.0
HKD1_k127_548047_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1384.0
HKD1_k127_548047_1 cellulose binding - - - 0.0 1255.0
HKD1_k127_548047_2 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 465.0
HKD1_k127_548047_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 452.0
HKD1_k127_548047_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 387.0
HKD1_k127_548047_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 266.0
HKD1_k127_548047_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000001266 186.0
HKD1_k127_548047_7 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000178 163.0
HKD1_k127_548047_8 nitric oxide dioxygenase activity - - - 0.00000000000000000001585 103.0
HKD1_k127_548047_9 Domain of unknown function (DUF4136) - - - 0.000005522 55.0
HKD1_k127_551257_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 342.0
HKD1_k127_551257_1 aminoacyl-tRNA hydrolase activity K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000004554 190.0
HKD1_k127_551257_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000007053 138.0
HKD1_k127_551257_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000001036 102.0
HKD1_k127_551257_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000001774 80.0
HKD1_k127_5566769_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1032.0
HKD1_k127_5566769_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000004085 55.0
HKD1_k127_5593057_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 322.0
HKD1_k127_5593057_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000004205 166.0
HKD1_k127_5600155_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 529.0
HKD1_k127_5600155_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 434.0
HKD1_k127_5600155_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 311.0
HKD1_k127_5600155_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008989 288.0
HKD1_k127_5600155_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000001704 246.0
HKD1_k127_5600155_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001417 164.0
HKD1_k127_5600155_6 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000001365 91.0
HKD1_k127_5600155_7 PFAM FecR protein - - - 0.0000000000002351 83.0
HKD1_k127_5600155_8 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.00000000125 60.0
HKD1_k127_5641866_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 490.0
HKD1_k127_5641866_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 401.0
HKD1_k127_5641866_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 350.0
HKD1_k127_5641866_3 Membrane - - - 0.00000000000000000000000000000000000000000000001539 195.0
HKD1_k127_5701545_0 transcription factor binding K02584 - - 1.147e-203 647.0
HKD1_k127_5701545_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 579.0
HKD1_k127_5701545_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 376.0
HKD1_k127_5701545_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000047 197.0
HKD1_k127_5701545_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000002272 130.0
HKD1_k127_5701545_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000665 69.0
HKD1_k127_5701545_6 Lysine exporter protein (Lyse ygga) - - - 0.00000004765 63.0
HKD1_k127_5701545_7 Glycosyl transferase family 41 - - - 0.0000002425 64.0
HKD1_k127_5708127_0 mRNA catabolic process K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 460.0
HKD1_k127_5708127_10 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000002001 173.0
HKD1_k127_5708127_11 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000003255 168.0
HKD1_k127_5708127_12 O-Antigen ligase K18814 - - 0.000000000000000000000001119 118.0
HKD1_k127_5708127_13 Protein of unknown function, DUF481 K07283 - - 0.00000000009536 72.0
HKD1_k127_5708127_14 Exonuclease VII small subunit - - - 0.0000000001053 66.0
HKD1_k127_5708127_15 Belongs to the UPF0434 family K09791 - - 0.0000001968 55.0
HKD1_k127_5708127_2 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 354.0
HKD1_k127_5708127_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 296.0
HKD1_k127_5708127_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007596 284.0
HKD1_k127_5708127_5 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008366 286.0
HKD1_k127_5708127_6 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000001171 267.0
HKD1_k127_5708127_7 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000001951 243.0
HKD1_k127_5708127_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000008192 203.0
HKD1_k127_5708127_9 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000007829 181.0
HKD1_k127_5858848_0 PFAM Type II secretion system protein E K02652 - - 2.799e-208 680.0
HKD1_k127_5858848_1 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 332.0
HKD1_k127_5858848_10 general secretion pathway protein K02456 - - 0.0000000000000000000000000000000001804 138.0
HKD1_k127_5858848_11 Sigma-70 region 2 K03088 - - 0.00000000000000000005747 99.0
HKD1_k127_5858848_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000002775 88.0
HKD1_k127_5858848_13 general secretion pathway protein K02456,K02650 - - 0.000000000000002867 87.0
HKD1_k127_5858848_14 phosphoribosylformylglycinamidine synthase activity K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000006735 53.0
HKD1_k127_5858848_15 - - - - 0.0001287 54.0
HKD1_k127_5858848_16 PFAM Fimbrial assembly family protein K02663 - - 0.0001331 52.0
HKD1_k127_5858848_17 Type ii and iii secretion system protein - - - 0.000207 52.0
HKD1_k127_5858848_2 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 302.0
HKD1_k127_5858848_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000004274 240.0
HKD1_k127_5858848_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000001503 209.0
HKD1_k127_5858848_5 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000001401 208.0
HKD1_k127_5858848_6 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000002108 177.0
HKD1_k127_5858848_7 beta-lactamase - - - 0.000000000000000000000000000000000000000000000678 177.0
HKD1_k127_5858848_8 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000001686 162.0
HKD1_k127_5858848_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000001293 153.0
HKD1_k127_5889778_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1054.0
HKD1_k127_5889778_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 447.0
HKD1_k127_5889778_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 367.0
HKD1_k127_5889778_3 response regulator - - - 0.00000000000000000000000000000000000000000000000003069 190.0
HKD1_k127_5889778_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0004604 43.0
HKD1_k127_5921810_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000002984 149.0
HKD1_k127_5921810_1 - - - - 0.0000002203 61.0
HKD1_k127_5931790_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 598.0
HKD1_k127_5931790_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
HKD1_k127_5931790_2 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 343.0
HKD1_k127_5931790_3 nucleic acid-binding protein, contains PIN domain K07065 - - 0.0000000000000000000000000001101 124.0
HKD1_k127_5931790_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000003682 55.0
HKD1_k127_5947803_0 phosphoserine phosphatase activity K07052,K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000003217 182.0
HKD1_k127_5947803_1 Domain of unknown function (DUF4412) - - - 0.000000000000000000000000000000002189 140.0
HKD1_k127_5947803_2 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000007411 131.0
HKD1_k127_599325_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0004171 51.0
HKD1_k127_6039111_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 460.0
HKD1_k127_6039111_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000112 175.0
HKD1_k127_6039860_0 Hexosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 302.0
HKD1_k127_6039860_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
HKD1_k127_6039860_2 hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 251.0
HKD1_k127_6039860_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000004426 209.0
HKD1_k127_6039860_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000001566 201.0
HKD1_k127_6039860_5 FMN binding - - - 0.000000000000000000000000000001035 135.0
HKD1_k127_6039860_7 Uncharacterised nucleotidyltransferase - - - 0.00000000000002327 87.0
HKD1_k127_6041009_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005348 276.0
HKD1_k127_6041009_1 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000002161 184.0
HKD1_k127_6041009_2 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000002502 153.0
HKD1_k127_6041009_3 PFAM Glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000001981 134.0
HKD1_k127_6041009_4 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.0000000000000000006722 98.0
HKD1_k127_6041009_5 Acetyltransferase (GNAT) domain - - - 0.0000000007719 70.0
HKD1_k127_6041009_6 PFAM Glycosyl transferases group 1 - - - 0.000000001629 67.0
HKD1_k127_6049520_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.66e-224 698.0
HKD1_k127_6049520_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 394.0
HKD1_k127_6049520_2 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000005463 224.0
HKD1_k127_6049520_3 Permease MlaE K02066 - - 0.000009185 54.0
HKD1_k127_6111719_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1005.0
HKD1_k127_6111719_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000746 141.0
HKD1_k127_6143100_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 485.0
HKD1_k127_6143100_1 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 347.0
HKD1_k127_6143100_2 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 309.0
HKD1_k127_6143100_3 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000001659 122.0
HKD1_k127_6143100_4 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000001724 81.0
HKD1_k127_6143100_5 DnaJ molecular chaperone homology domain - - - 0.00006973 55.0
HKD1_k127_6168132_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1037.0
HKD1_k127_6168132_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.921e-298 936.0
HKD1_k127_6168132_10 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000000000000002666 182.0
HKD1_k127_6168132_11 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000004543 198.0
HKD1_k127_6168132_12 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000005423 160.0
HKD1_k127_6168132_13 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000004407 133.0
HKD1_k127_6168132_14 helix_turn_helix, mercury resistance - - - 0.00000000000000002904 91.0
HKD1_k127_6168132_16 Two component transcriptional regulator, winged helix family K02483 - - 0.0002049 52.0
HKD1_k127_6168132_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.016e-242 783.0
HKD1_k127_6168132_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 621.0
HKD1_k127_6168132_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 467.0
HKD1_k127_6168132_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 329.0
HKD1_k127_6168132_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 350.0
HKD1_k127_6168132_7 formate dehydrogenase K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 327.0
HKD1_k127_6168132_8 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001636 252.0
HKD1_k127_6168132_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_6175253_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1519.0
HKD1_k127_6175253_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HKD1_k127_6175253_2 phosphoribosylamine-glycine ligase activity K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 437.0
HKD1_k127_6175253_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 396.0
HKD1_k127_6175253_5 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000003324 147.0
HKD1_k127_6175253_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000002476 81.0
HKD1_k127_6175253_7 Bacterial transcriptional activator domain - - - 0.0003775 52.0
HKD1_k127_6236036_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 597.0
HKD1_k127_6236036_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 523.0
HKD1_k127_6236036_10 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000007624 138.0
HKD1_k127_6236036_11 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000001089 126.0
HKD1_k127_6236036_12 amine dehydrogenase activity K09815 - - 0.00000000000000005714 94.0
HKD1_k127_6236036_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 447.0
HKD1_k127_6236036_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 382.0
HKD1_k127_6236036_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 398.0
HKD1_k127_6236036_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 371.0
HKD1_k127_6236036_6 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 306.0
HKD1_k127_6236036_7 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000001553 257.0
HKD1_k127_6236036_8 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000005209 226.0
HKD1_k127_6236036_9 Two component regulator propeller - - - 0.0000000000000000000000000000000000006969 160.0
HKD1_k127_628343_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.976e-243 788.0
HKD1_k127_628343_1 UDP-N-acetylmuramate-L-alanine ligase activity K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 481.0
HKD1_k127_628343_10 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000007408 152.0
HKD1_k127_628343_11 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000002517 130.0
HKD1_k127_628343_12 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000000000001027 82.0
HKD1_k127_628343_13 Essential cell division protein K03589 - - 0.000001125 62.0
HKD1_k127_628343_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00002629 55.0
HKD1_k127_628343_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 430.0
HKD1_k127_628343_3 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 392.0
HKD1_k127_628343_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 389.0
HKD1_k127_628343_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 327.0
HKD1_k127_628343_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002265 287.0
HKD1_k127_628343_7 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005248 305.0
HKD1_k127_628343_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000001116 256.0
HKD1_k127_628343_9 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000003963 214.0
HKD1_k127_6290369_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 567.0
HKD1_k127_6290369_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 389.0
HKD1_k127_6290369_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 405.0
HKD1_k127_6290369_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 290.0
HKD1_k127_6290369_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003888 261.0
HKD1_k127_6290369_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000004305 164.0
HKD1_k127_6290369_6 histone H2A K63-linked ubiquitination K03581,K12132 - 2.7.11.1,3.1.11.5 0.0000000000006601 74.0
HKD1_k127_6290369_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000001389 72.0
HKD1_k127_6290369_8 Virulence factor BrkB K07058 - - 0.000000002729 70.0
HKD1_k127_6290369_9 - - - - 0.000004152 55.0
HKD1_k127_6295852_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 394.0
HKD1_k127_6295852_1 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 270.0
HKD1_k127_6295852_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000006545 244.0
HKD1_k127_6295852_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000936 235.0
HKD1_k127_6295852_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000007873 195.0
HKD1_k127_6295852_5 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000001972 190.0
HKD1_k127_6295852_6 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000003922 138.0
HKD1_k127_6295852_7 - - - - 0.00000000001403 78.0
HKD1_k127_6320937_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 503.0
HKD1_k127_6320937_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 304.0
HKD1_k127_6320937_2 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000001632 192.0
HKD1_k127_6320937_3 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000008305 169.0
HKD1_k127_6320937_4 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000003019 155.0
HKD1_k127_6328586_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 487.0
HKD1_k127_6328586_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 406.0
HKD1_k127_6328586_10 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000003049 172.0
HKD1_k127_6328586_11 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000003813 165.0
HKD1_k127_6328586_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.00000000000000000000000001621 115.0
HKD1_k127_6328586_13 COG1309 Transcriptional regulator - - - 0.00000000000000000000001332 108.0
HKD1_k127_6328586_14 thiolester hydrolase activity K06889 - - 0.0000000000000001272 94.0
HKD1_k127_6328586_15 redox-active disulfide protein 2 - - - 0.000000000000004908 84.0
HKD1_k127_6328586_16 Protein of unknown function (DUF2752) - - - 0.0000000000001338 74.0
HKD1_k127_6328586_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 361.0
HKD1_k127_6328586_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 322.0
HKD1_k127_6328586_4 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005572 253.0
HKD1_k127_6328586_5 coagulation factor 5 8 type - - - 0.00000000000000000000000000000000000000000000000000000000000001855 231.0
HKD1_k127_6328586_6 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000005847 201.0
HKD1_k127_6328586_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000004072 213.0
HKD1_k127_6328586_9 AAA domain - - - 0.000000000000000000000000000000000000000000000000001749 188.0
HKD1_k127_6348789_0 ImcF-related N-terminal domain K11891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 317.0
HKD1_k127_6348789_1 TIGRFAM type VI secretion protein, VC_A0114 family K11893 - - 0.00000000000000000000000000000000000000000000000000000000000004743 233.0
HKD1_k127_6348789_2 Type VI secretion system protein DotU - - - 0.0000000003532 69.0
HKD1_k127_6369307_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 436.0
HKD1_k127_6369307_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 406.0
HKD1_k127_6369307_10 Bacterial membrane protein YfhO - - - 0.00000126 62.0
HKD1_k127_6369307_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 303.0
HKD1_k127_6369307_3 Major facilitator K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 309.0
HKD1_k127_6369307_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002464 268.0
HKD1_k127_6369307_5 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000003354 199.0
HKD1_k127_6369307_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000003862 160.0
HKD1_k127_6369307_7 Lytic transglycolase K03642 - - 0.000000000000000000000000000001255 134.0
HKD1_k127_6369307_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000007648 121.0
HKD1_k127_6369307_9 Bacterial membrane protein, YfhO - - - 0.0000004169 63.0
HKD1_k127_6392092_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001253 286.0
HKD1_k127_6392092_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000008134 70.0
HKD1_k127_6392092_2 diguanylate cyclase - - - 0.0000000221 67.0
HKD1_k127_6392092_3 RDD family - - - 0.00007029 55.0
HKD1_k127_6409811_0 Belongs to the malate synthase family K01638 - 2.3.3.9 7.756e-225 710.0
HKD1_k127_6409811_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 337.0
HKD1_k127_6409811_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 336.0
HKD1_k127_6409811_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000001485 164.0
HKD1_k127_6409811_4 stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000002575 136.0
HKD1_k127_6409811_5 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000002283 128.0
HKD1_k127_6409811_6 - - - - 0.000000001068 64.0
HKD1_k127_6424260_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.776e-245 801.0
HKD1_k127_6424260_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 479.0
HKD1_k127_6424260_10 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000002917 180.0
HKD1_k127_6424260_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000349 162.0
HKD1_k127_6424260_12 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000006482 150.0
HKD1_k127_6424260_13 DinB family - - - 0.000000000000000000000000000000000001753 154.0
HKD1_k127_6424260_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000625 140.0
HKD1_k127_6424260_15 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001422 140.0
HKD1_k127_6424260_16 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000002105 136.0
HKD1_k127_6424260_17 Abortive infection C-terminus - - - 0.000000000000000000000000000001411 131.0
HKD1_k127_6424260_18 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000005367 107.0
HKD1_k127_6424260_19 FeoA K04758 - - 0.00000000000000000000009695 100.0
HKD1_k127_6424260_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 317.0
HKD1_k127_6424260_20 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000001064 104.0
HKD1_k127_6424260_21 Ferrous iron transport protein B K04759 - - 0.0000000000000000005504 103.0
HKD1_k127_6424260_22 General secretory system II protein E domain protein K02652 - - 0.0000000000000001737 92.0
HKD1_k127_6424260_23 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000005213 74.0
HKD1_k127_6424260_25 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000007196 71.0
HKD1_k127_6424260_26 amine dehydrogenase activity K01077,K07004,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.3.1 0.0000000007471 72.0
HKD1_k127_6424260_27 outer membrane autotransporter barrel domain protein - - - 0.000000003829 71.0
HKD1_k127_6424260_28 Tetratricopeptide TPR_2 repeat protein - - - 0.0001779 54.0
HKD1_k127_6424260_3 enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000005344 251.0
HKD1_k127_6424260_4 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006251 245.0
HKD1_k127_6424260_5 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000005638 250.0
HKD1_k127_6424260_6 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000005839 204.0
HKD1_k127_6424260_7 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000021 215.0
HKD1_k127_6424260_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000001881 217.0
HKD1_k127_6424260_9 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000004398 190.0
HKD1_k127_6451405_0 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001044 241.0
HKD1_k127_6451405_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000003964 204.0
HKD1_k127_6451405_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.00000000000000000002083 97.0
HKD1_k127_6574172_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 9.768e-217 678.0
HKD1_k127_6574172_1 AMP-binding enzyme K01897 - 6.2.1.3 1.716e-206 659.0
HKD1_k127_6574172_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 606.0
HKD1_k127_6574172_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 555.0
HKD1_k127_6574172_4 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 376.0
HKD1_k127_6574172_5 homoserine kinase activity K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 359.0
HKD1_k127_6574172_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000001644 202.0
HKD1_k127_6587055_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 584.0
HKD1_k127_6587055_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 477.0
HKD1_k127_6587055_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 452.0
HKD1_k127_6587055_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 308.0
HKD1_k127_6587055_4 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000003709 239.0
HKD1_k127_6587055_5 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000001633 203.0
HKD1_k127_6587055_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000108 119.0
HKD1_k127_6617583_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1589.0
HKD1_k127_6617583_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 407.0
HKD1_k127_6617583_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000003871 265.0
HKD1_k127_6626246_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 415.0
HKD1_k127_6626246_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
HKD1_k127_6626246_10 - - - - 0.00000000008056 75.0
HKD1_k127_6626246_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000001194 70.0
HKD1_k127_6626246_12 - - - - 0.000000548 58.0
HKD1_k127_6626246_13 Inactive carboxypeptidase-like protein X2 K08639 - - 0.000488 48.0
HKD1_k127_6626246_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000159 246.0
HKD1_k127_6626246_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000003107 226.0
HKD1_k127_6626246_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000002158 226.0
HKD1_k127_6626246_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000001127 206.0
HKD1_k127_6626246_6 - - - - 0.00000000000000000000000000000000000000000000133 178.0
HKD1_k127_6626246_7 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000001532 157.0
HKD1_k127_6626246_8 - - - - 0.000000000000000000000000000000000005955 149.0
HKD1_k127_6626246_9 Helix-turn-helix domain - - - 0.00000000000009822 81.0
HKD1_k127_6707288_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 584.0
HKD1_k127_6707288_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000002689 207.0
HKD1_k127_6716430_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 9.003e-276 868.0
HKD1_k127_6716430_1 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 456.0
HKD1_k127_6716430_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 341.0
HKD1_k127_6716430_3 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000002067 110.0
HKD1_k127_6716430_4 - - - - 0.0000000000000000000003538 104.0
HKD1_k127_675795_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.262e-282 895.0
HKD1_k127_675795_1 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 470.0
HKD1_k127_675795_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000001181 187.0
HKD1_k127_675795_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000002672 173.0
HKD1_k127_675795_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000219 143.0
HKD1_k127_675795_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000002469 73.0
HKD1_k127_6766034_0 Peptidase m28 - - - 1.283e-210 670.0
HKD1_k127_6766034_1 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 434.0
HKD1_k127_6766034_2 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
HKD1_k127_6766034_3 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 315.0
HKD1_k127_6766034_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000376 287.0
HKD1_k127_6766034_5 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003723 244.0
HKD1_k127_6766034_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000006159 234.0
HKD1_k127_6766034_7 PFAM CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000001205 197.0
HKD1_k127_6766034_8 phosphate-selective porin O and P - - - 0.0000000000000000000000000000003597 137.0
HKD1_k127_6766034_9 diguanylate cyclase - - - 0.00000000000000000000000000002156 128.0
HKD1_k127_6789585_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1166.0
HKD1_k127_6847119_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 370.0
HKD1_k127_6847119_1 gluconolactonase activity - - - 0.000001882 59.0
HKD1_k127_6847119_2 Involved in the tonB-independent uptake of proteins - - - 0.000004675 49.0
HKD1_k127_6867118_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 574.0
HKD1_k127_6867118_1 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 540.0
HKD1_k127_6867118_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 341.0
HKD1_k127_6867118_3 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 281.0
HKD1_k127_6867118_4 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006175 288.0
HKD1_k127_6867118_5 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000009667 194.0
HKD1_k127_6867118_6 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000006523 185.0
HKD1_k127_6867118_7 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000001463 160.0
HKD1_k127_6867118_8 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000003619 108.0
HKD1_k127_6867118_9 DNA polymerase K02337 - 2.7.7.7 0.0006148 46.0
HKD1_k127_6878642_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 377.0
HKD1_k127_6878642_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000001551 215.0
HKD1_k127_6878642_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000003274 158.0
HKD1_k127_6878642_3 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000001516 103.0
HKD1_k127_6878642_4 Tetratricopeptide repeat - - - 0.00000000000000000002113 100.0
HKD1_k127_6878642_5 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000002898 101.0
HKD1_k127_6907314_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1316.0
HKD1_k127_6907314_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 6.302e-272 885.0
HKD1_k127_6907314_10 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000005595 123.0
HKD1_k127_6907314_11 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000004534 117.0
HKD1_k127_6907314_12 Peptidase M56 - - - 0.000000000000001239 92.0
HKD1_k127_6907314_13 PFAM O-Antigen - - - 0.00000007747 66.0
HKD1_k127_6907314_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 452.0
HKD1_k127_6907314_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 372.0
HKD1_k127_6907314_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 350.0
HKD1_k127_6907314_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 325.0
HKD1_k127_6907314_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000004355 206.0
HKD1_k127_6907314_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000011 166.0
HKD1_k127_6907314_8 von Willebrand factor, type A - - - 0.000000000000000000000000000000002902 150.0
HKD1_k127_6907314_9 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000006261 131.0
HKD1_k127_6932833_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 302.0
HKD1_k127_6932833_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000009698 185.0
HKD1_k127_6932833_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000006105 184.0
HKD1_k127_6978877_0 4Fe-4S dicluster domain K00184 - - 2.934e-319 1018.0
HKD1_k127_6978877_1 Polysulphide reductase, NrfD K00185 - - 9.357e-203 648.0
HKD1_k127_6978877_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 398.0
HKD1_k127_6978877_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
HKD1_k127_6978877_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 342.0
HKD1_k127_6978877_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 274.0
HKD1_k127_6978877_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002861 235.0
HKD1_k127_6978877_7 Protein of unknown function (DUF3341) - - - 0.0000000000000005712 83.0
HKD1_k127_7008276_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 4.26e-200 639.0
HKD1_k127_7008276_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 356.0
HKD1_k127_7008276_10 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000697 133.0
HKD1_k127_7008276_11 TPR repeat - - - 0.0000000000000000000004519 106.0
HKD1_k127_7008276_12 amino acid K03294 - - 0.000000000000001224 88.0
HKD1_k127_7008276_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K20276 - - 0.0000003232 65.0
HKD1_k127_7008276_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 339.0
HKD1_k127_7008276_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 318.0
HKD1_k127_7008276_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 299.0
HKD1_k127_7008276_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000005528 243.0
HKD1_k127_7008276_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000005454 241.0
HKD1_k127_7008276_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000006325 211.0
HKD1_k127_7008276_8 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000008103 178.0
HKD1_k127_7008276_9 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000155 179.0
HKD1_k127_7032394_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.019e-233 737.0
HKD1_k127_7032394_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000002256 140.0
HKD1_k127_7032394_2 Protein of unknown function (DUF2892) - - - 0.000001696 52.0
HKD1_k127_7039454_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 458.0
HKD1_k127_7039454_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 346.0
HKD1_k127_7039454_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 319.0
HKD1_k127_7039454_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 310.0
HKD1_k127_7039454_4 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000002313 230.0
HKD1_k127_7039454_5 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000006271 147.0
HKD1_k127_7039454_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0001341 45.0
HKD1_k127_7050648_0 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 523.0
HKD1_k127_7050648_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 471.0
HKD1_k127_7050648_10 phosphatase activity K07025 - - 0.000000000000000000000000000000000009532 152.0
HKD1_k127_7050648_11 TonB C terminal K03832 - - 0.00000000000000000000000006773 119.0
HKD1_k127_7050648_12 redox-active disulfide protein 2 - - - 0.00000000000000003823 86.0
HKD1_k127_7050648_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000003039 75.0
HKD1_k127_7050648_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000003232 69.0
HKD1_k127_7050648_15 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000004048 67.0
HKD1_k127_7050648_16 PFAM PKD domain containing protein - - - 0.000000001558 73.0
HKD1_k127_7050648_17 Short C-terminal domain K08982 - - 0.0000008372 56.0
HKD1_k127_7050648_18 Aminotransferase class-V K04487 - 2.8.1.7 0.0002278 54.0
HKD1_k127_7050648_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 428.0
HKD1_k127_7050648_3 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000208 246.0
HKD1_k127_7050648_4 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000001317 210.0
HKD1_k127_7050648_5 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000001466 207.0
HKD1_k127_7050648_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000007732 193.0
HKD1_k127_7050648_7 DGC domain - - - 0.000000000000000000000000000000000000002312 153.0
HKD1_k127_7050648_8 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000006571 151.0
HKD1_k127_7050648_9 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000001208 148.0
HKD1_k127_7094715_0 Radical SAM - - - 5.642e-217 720.0
HKD1_k127_7094715_1 peptidyl-tyrosine sulfation - - - 6.223e-215 696.0
HKD1_k127_7094715_10 serine-type endopeptidase activity K08372 - - 0.000000000000000000000000000000000000000000000000000000000000003137 232.0
HKD1_k127_7094715_11 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000002689 192.0
HKD1_k127_7094715_12 serine threonine protein kinase - - - 0.000000000000000000000000000000000000006444 164.0
HKD1_k127_7094715_13 STAS domain K04749 - - 0.000000000000000000000000000000000012 139.0
HKD1_k127_7094715_14 HD domain - - - 0.000000000000000000000000000005634 130.0
HKD1_k127_7094715_15 Zn peptidase - - - 0.00000000000000000000000005634 124.0
HKD1_k127_7094715_16 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000006256 119.0
HKD1_k127_7094715_17 Glutaredoxin K03676 - - 0.00000174 51.0
HKD1_k127_7094715_18 CAAX protease self-immunity K07052 - - 0.00008181 53.0
HKD1_k127_7094715_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 602.0
HKD1_k127_7094715_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 545.0
HKD1_k127_7094715_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 553.0
HKD1_k127_7094715_5 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 448.0
HKD1_k127_7094715_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004536 307.0
HKD1_k127_7094715_7 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 271.0
HKD1_k127_7094715_8 PFAM ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004858 277.0
HKD1_k127_7094715_9 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001224 263.0
HKD1_k127_7115532_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 2172.0
HKD1_k127_7115532_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.281e-241 756.0
HKD1_k127_7115532_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 622.0
HKD1_k127_7115532_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 390.0
HKD1_k127_7115532_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 385.0
HKD1_k127_7115532_5 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000004681 149.0
HKD1_k127_715916_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 530.0
HKD1_k127_715916_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000004111 75.0
HKD1_k127_715916_2 Bacterial membrane protein, YfhO - - - 0.00002985 57.0
HKD1_k127_7190355_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 456.0
HKD1_k127_7190355_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
HKD1_k127_7190355_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000002943 183.0
HKD1_k127_7190355_11 - - - - 0.00000000000000000005697 91.0
HKD1_k127_7190355_12 Bacterial Ig-like domain (group 3) - - - 0.000000000189 70.0
HKD1_k127_7190355_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 350.0
HKD1_k127_7190355_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 331.0
HKD1_k127_7190355_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001279 258.0
HKD1_k127_7190355_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001685 280.0
HKD1_k127_7190355_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000003004 244.0
HKD1_k127_7190355_7 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000004643 247.0
HKD1_k127_7190355_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000002842 237.0
HKD1_k127_7190355_9 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000269 198.0
HKD1_k127_7226599_0 cellulose binding - - - 1.471e-244 784.0
HKD1_k127_7226599_1 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 411.0
HKD1_k127_7226599_2 arylamine N-acetyltransferase activity K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
HKD1_k127_7226599_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008628 287.0
HKD1_k127_7226599_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000002061 189.0
HKD1_k127_7226599_5 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000006377 154.0
HKD1_k127_7226599_6 overlaps another CDS with the same product name - - - 0.00000000000000001341 93.0
HKD1_k127_7226599_7 Protein of unknown function (DUF2752) - - - 0.000000006089 68.0
HKD1_k127_7226599_8 Aldo/keto reductase family - - - 0.0000003245 57.0
HKD1_k127_7226599_9 - - - - 0.0001029 55.0
HKD1_k127_7246842_0 DNA topoisomerase K02470,K02622 - 5.99.1.3 2.981e-273 854.0
HKD1_k127_7246842_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 585.0
HKD1_k127_7246842_10 Domain of unknown function (DUF4912) K09942 - - 0.0000000000009607 82.0
HKD1_k127_7246842_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 463.0
HKD1_k127_7246842_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 321.0
HKD1_k127_7246842_4 nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000001303 174.0
HKD1_k127_7246842_5 Outer membrane receptor - - - 0.00000000000000000000000000000000000000002269 176.0
HKD1_k127_7246842_6 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000009745 137.0
HKD1_k127_7246842_7 AAA domain - - - 0.00000000000000000000000000002219 131.0
HKD1_k127_7246842_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000008583 124.0
HKD1_k127_7246842_9 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000002569 85.0
HKD1_k127_7263804_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 558.0
HKD1_k127_7263804_1 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 410.0
HKD1_k127_7263804_10 Tetratricopeptide repeat - - - 0.00000001331 68.0
HKD1_k127_7263804_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 384.0
HKD1_k127_7263804_3 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 300.0
HKD1_k127_7263804_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003491 285.0
HKD1_k127_7263804_5 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002411 239.0
HKD1_k127_7263804_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000002453 236.0
HKD1_k127_7263804_7 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000105 199.0
HKD1_k127_7263804_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000004491 203.0
HKD1_k127_7263804_9 NUDIX domain - - - 0.000000000000000000000000000000000000008404 164.0
HKD1_k127_7271557_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001002 278.0
HKD1_k127_7271557_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 265.0
HKD1_k127_7271557_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000001 179.0
HKD1_k127_7271557_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000008195 96.0
HKD1_k127_7290290_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1292.0
HKD1_k127_7380820_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 538.0
HKD1_k127_7380820_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000159 200.0
HKD1_k127_7380820_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000007793 164.0
HKD1_k127_7380820_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000001416 155.0
HKD1_k127_7380820_4 Lipoprotein-releasing system permease protein K09808 - - 0.00000000000003299 85.0
HKD1_k127_7430139_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1013.0
HKD1_k127_7430139_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 1.112e-254 793.0
HKD1_k127_7430139_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000001814 153.0
HKD1_k127_7430139_11 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.00000000000000000000000000000002619 137.0
HKD1_k127_7430139_12 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000001014 113.0
HKD1_k127_7430139_2 lysine biosynthetic process via aminoadipic acid - - - 1.437e-219 709.0
HKD1_k127_7430139_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 565.0
HKD1_k127_7430139_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 409.0
HKD1_k127_7430139_5 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 407.0
HKD1_k127_7430139_6 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 373.0
HKD1_k127_7430139_7 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 358.0
HKD1_k127_7430139_8 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001526 263.0
HKD1_k127_7430139_9 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000157 192.0
HKD1_k127_7435453_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.067e-233 738.0
HKD1_k127_7435453_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 492.0
HKD1_k127_7435453_2 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000002014 134.0
HKD1_k127_7435453_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000003141 96.0
HKD1_k127_7435453_4 Biotin-requiring enzyme - - - 0.0000000000007113 82.0
HKD1_k127_7490785_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 404.0
HKD1_k127_7490785_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 353.0
HKD1_k127_7490785_10 Smr domain - - - 0.000000000000000000008151 95.0
HKD1_k127_7490785_11 Metallo-beta-lactamase superfamily - - - 0.0000000000001278 81.0
HKD1_k127_7490785_12 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000007492 79.0
HKD1_k127_7490785_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000001309 66.0
HKD1_k127_7490785_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001739 231.0
HKD1_k127_7490785_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000175 207.0
HKD1_k127_7490785_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000002547 178.0
HKD1_k127_7490785_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000009234 163.0
HKD1_k127_7490785_6 methylamine metabolic process - - - 0.0000000000000000000000000000000000001472 149.0
HKD1_k127_7490785_7 PFAM Curli production assembly transport component CsgG - - - 0.00000000000000000000000000000003769 137.0
HKD1_k127_7490785_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000000002933 131.0
HKD1_k127_7490785_9 Belongs to the Fur family K09825 - - 0.0000000000000000000000000003573 118.0
HKD1_k127_752495_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 3.247e-218 699.0
HKD1_k127_752495_1 - - - - 0.00000000000000000000000000000000000000000000001341 171.0
HKD1_k127_7564730_0 Tricorn protease C1 domain K08676 - - 7.57e-251 822.0
HKD1_k127_7564730_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 352.0
HKD1_k127_761525_0 PFAM GlcNAc-PI de-N-acetylase - - - 1.93e-244 780.0
HKD1_k127_761525_1 beta-lactamase - - - 1.545e-223 719.0
HKD1_k127_761525_10 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001186 258.0
HKD1_k127_761525_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000004677 242.0
HKD1_k127_761525_12 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000001973 231.0
HKD1_k127_761525_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000885 222.0
HKD1_k127_761525_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000298 216.0
HKD1_k127_761525_15 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000005995 210.0
HKD1_k127_761525_16 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000000000000000000000004066 154.0
HKD1_k127_761525_18 Mannosyltransferase (PIG-V) - - - 0.00000000000000000001278 106.0
HKD1_k127_761525_19 CAAX protease self-immunity K07052 - - 0.000000000007134 80.0
HKD1_k127_761525_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 544.0
HKD1_k127_761525_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 492.0
HKD1_k127_761525_4 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 481.0
HKD1_k127_761525_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 453.0
HKD1_k127_761525_6 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 433.0
HKD1_k127_761525_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 427.0
HKD1_k127_761525_8 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 388.0
HKD1_k127_761525_9 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 383.0
HKD1_k127_762550_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 381.0
HKD1_k127_762550_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 347.0
HKD1_k127_762550_2 PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000535 238.0
HKD1_k127_762550_3 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000009553 119.0
HKD1_k127_762550_4 Histidine kinase K13040 - 2.7.13.3 0.00000000000000001185 91.0
HKD1_k127_7628657_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 616.0
HKD1_k127_7628657_1 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 387.0
HKD1_k127_7628657_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000002119 209.0
HKD1_k127_7628657_3 membrane - - - 0.0001282 46.0
HKD1_k127_762911_0 Phosphoglucose isomerase K01810 - 5.3.1.9 1.37e-280 883.0
HKD1_k127_762911_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 3.258e-216 683.0
HKD1_k127_762911_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 543.0
HKD1_k127_762911_3 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
HKD1_k127_762911_4 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 280.0
HKD1_k127_762911_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000003026 187.0
HKD1_k127_762911_6 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.000000000000000000000000000000000000000003779 156.0
HKD1_k127_762911_7 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000739 120.0
HKD1_k127_7668471_0 Large extracellular alpha-helical protein - - - 0.0 2199.0
HKD1_k127_7668471_1 Peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 535.0
HKD1_k127_7668471_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 366.0
HKD1_k127_7668471_3 Belongs to the UPF0441 family - - - 0.00004487 45.0
HKD1_k127_7671723_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 422.0
HKD1_k127_7671723_1 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000001121 212.0
HKD1_k127_7671723_2 PFAM Rhomboid family protein - - - 0.00000000000000000000001062 103.0
HKD1_k127_7677179_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 490.0
HKD1_k127_7677179_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000001415 196.0
HKD1_k127_7677179_2 TonB-dependent Receptor Plug Domain - - - 0.000002897 59.0
HKD1_k127_7692302_0 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 528.0
HKD1_k127_7692302_1 - - - - 0.0000000003086 67.0
HKD1_k127_7725397_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
HKD1_k127_7725397_1 COG1045 Serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000001028 187.0
HKD1_k127_7725397_2 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000003703 96.0
HKD1_k127_7725397_3 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.0000000000000002026 87.0
HKD1_k127_7725397_4 Tetratricopeptide repeat - - - 0.00000004316 64.0
HKD1_k127_7725397_5 Thioredoxin-like K01829 - 5.3.4.1 0.0004214 50.0
HKD1_k127_7726748_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 288.0
HKD1_k127_7726748_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000007459 154.0
HKD1_k127_7726748_2 Belongs to the UPF0310 family - - - 0.0000000000000000000002018 102.0
HKD1_k127_7726748_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000006693 95.0
HKD1_k127_7730728_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.924e-199 642.0
HKD1_k127_7730728_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 560.0
HKD1_k127_7730728_10 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000015 169.0
HKD1_k127_7730728_11 Protein of unknown function, DUF547 - - - 0.000000000000000000106 104.0
HKD1_k127_7730728_12 Virulence activator alpha C-term - - - 0.0000000000000000126 91.0
HKD1_k127_7730728_13 lipolytic protein G-D-S-L family - - - 0.00000009635 63.0
HKD1_k127_7730728_14 Tetratricopeptide repeat - - - 0.0002133 52.0
HKD1_k127_7730728_2 TIGRFAM amidohydrolase K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 373.0
HKD1_k127_7730728_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 362.0
HKD1_k127_7730728_4 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 337.0
HKD1_k127_7730728_6 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000004169 219.0
HKD1_k127_7730728_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000003185 210.0
HKD1_k127_7730728_8 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000001508 203.0
HKD1_k127_7730728_9 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000389 193.0
HKD1_k127_774093_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.801e-303 964.0
HKD1_k127_774093_1 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 581.0
HKD1_k127_774093_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 577.0
HKD1_k127_774093_3 lytic transglycosylase - - - 0.000000000000000000000000000000000002687 146.0
HKD1_k127_7843845_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1155.0
HKD1_k127_7843845_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1069.0
HKD1_k127_7843845_10 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 313.0
HKD1_k127_7843845_11 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002044 296.0
HKD1_k127_7843845_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000005906 191.0
HKD1_k127_7843845_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000507 190.0
HKD1_k127_7843845_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000003836 191.0
HKD1_k127_7843845_15 DinB superfamily K07552 - - 0.0000000000000000000000000000000000000005017 154.0
HKD1_k127_7843845_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000005456 133.0
HKD1_k127_7843845_17 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000003442 113.0
HKD1_k127_7843845_18 - - - - 0.00000000005507 66.0
HKD1_k127_7843845_2 Carbamoyltransferase C-terminus K00612 - - 4.754e-258 810.0
HKD1_k127_7843845_20 lipolytic protein G-D-S-L family - - - 0.00000035 63.0
HKD1_k127_7843845_21 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000003963 57.0
HKD1_k127_7843845_22 GDSL-like Lipase/Acylhydrolase family - - - 0.0000005253 62.0
HKD1_k127_7843845_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 3.542e-248 773.0
HKD1_k127_7843845_4 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 3.563e-225 702.0
HKD1_k127_7843845_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 630.0
HKD1_k127_7843845_6 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 572.0
HKD1_k127_7843845_7 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 465.0
HKD1_k127_7843845_8 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 416.0
HKD1_k127_7843845_9 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
HKD1_k127_7890923_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 510.0
HKD1_k127_7890923_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000002805 203.0
HKD1_k127_7890923_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000003725 160.0
HKD1_k127_7890923_3 glycosyl transferase - - - 0.0000000000000000000000000000000001866 139.0
HKD1_k127_7890923_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000005074 94.0
HKD1_k127_7905261_0 Peptidase M16 inactive domain K07263 - - 3.433e-201 648.0
HKD1_k127_7905261_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 437.0
HKD1_k127_7905261_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000009658 249.0
HKD1_k127_7929351_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 416.0
HKD1_k127_7929351_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 365.0
HKD1_k127_7929351_2 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009167 290.0
HKD1_k127_7929351_3 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000001182 110.0
HKD1_k127_7929351_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000007902 87.0
HKD1_k127_7932314_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 539.0
HKD1_k127_7932314_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 368.0
HKD1_k127_7932314_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001584 298.0
HKD1_k127_7932314_3 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007504 260.0
HKD1_k127_7932314_4 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000005437 199.0
HKD1_k127_7932314_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000005262 180.0
HKD1_k127_7932314_6 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00001744 53.0
HKD1_k127_7934153_0 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 272.0
HKD1_k127_805586_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 504.0
HKD1_k127_805586_1 Bacterial transferase hexapeptide (six repeats) K21379 - 2.3.1.209 0.0000000000000000000000000000000000000000000000000000000000000000000000000002383 261.0
HKD1_k127_805586_2 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.00000000000000000000000000000000000000000000000000000006512 213.0
HKD1_k127_805586_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000004016 157.0
HKD1_k127_805586_4 Glycosyl transferases group 1 - - - 0.0000000000000003432 87.0
HKD1_k127_805586_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657 - 2.3.1.57 0.00000000002108 76.0
HKD1_k127_823444_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 503.0
HKD1_k127_823444_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 467.0
HKD1_k127_823444_2 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 390.0
HKD1_k127_823444_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 362.0
HKD1_k127_823444_4 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 301.0
HKD1_k127_823444_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009774 290.0
HKD1_k127_823444_6 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006108 241.0
HKD1_k127_823444_7 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000004837 217.0
HKD1_k127_823444_8 cellulose binding - - - 0.00000000326 67.0
HKD1_k127_823554_0 Heat shock 70 kDa protein K04043 - - 1.823e-291 906.0
HKD1_k127_823554_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 535.0
HKD1_k127_823554_10 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000691 138.0
HKD1_k127_823554_11 mitochondrial electron transport, ubiquinol to cytochrome c K01412,K07263,K17732 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005759,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016787,GO:0017087,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0023052,GO:0031090,GO:0031930,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045275,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0065007,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 3.4.24.64 0.0000000000000000000000000000002749 127.0
HKD1_k127_823554_12 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000005574 121.0
HKD1_k127_823554_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000242 126.0
HKD1_k127_823554_14 - - - - 0.000000000001722 80.0
HKD1_k127_823554_15 Domain of unknown function (DUF1844) - - - 0.000009166 53.0
HKD1_k127_823554_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 316.0
HKD1_k127_823554_3 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000001098 247.0
HKD1_k127_823554_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000009317 208.0
HKD1_k127_823554_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000002462 193.0
HKD1_k127_823554_6 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000001668 188.0
HKD1_k127_823554_7 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000007171 198.0
HKD1_k127_823554_8 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000001588 147.0
HKD1_k127_823554_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000534 145.0
HKD1_k127_930877_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 447.0
HKD1_k127_930877_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 365.0
HKD1_k127_930877_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000009979 123.0
HKD1_k127_930877_11 Biotin-lipoyl like K18990 - - 0.00000000000000001521 97.0
HKD1_k127_930877_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000004805 89.0
HKD1_k127_930877_13 - - - - 0.00000000000006985 84.0
HKD1_k127_930877_14 Redoxin K02199 - - 0.0008313 49.0
HKD1_k127_930877_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 314.0
HKD1_k127_930877_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 314.0
HKD1_k127_930877_4 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 249.0
HKD1_k127_930877_5 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000006614 229.0
HKD1_k127_930877_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000000000000000000002097 225.0
HKD1_k127_930877_7 metallopeptidase activity K01993,K13408,K16922 - - 0.0000000000000000000000000000000000000000000000000003695 210.0
HKD1_k127_930877_8 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000003962 186.0
HKD1_k127_930877_9 NlpC/P60 family - - - 0.000000000000000000000000000000000000004311 170.0
HKD1_k127_935065_0 Pro-kumamolisin, activation domain K08677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 409.0
HKD1_k127_935065_1 Domain of unknown function (DUF4126) - - - 0.000000000000000000004251 101.0
HKD1_k127_935065_2 - - - - 0.0000000000005127 77.0
HKD1_k127_981850_0 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000223 166.0
HKD1_k127_981850_1 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0032501,GO:0036211,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0046872,GO:0046914,GO:0048871,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:0097009,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000000000000000000000009529 170.0
HKD1_k127_981850_2 pfam nudix - - - 0.000000000000000000000000000000002206 136.0
HKD1_k127_981850_3 long-chain fatty acid transporting porin activity K06076 - - 0.00000003279 66.0