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Overview

ID MAG01725
Name HKD1_bin.42
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_E
Class Deferrimicrobia
Order Deferrimicrobiales
Family Deferrimicrobiaceae
Genus
Species
Assembly information
Completeness (%) 94.13
Contamination (%) 1.38
GC content (%) 68.0
N50 (bp) 22,577
Genome size (bp) 2,702,543

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2435

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1010890_0 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 547.0
HKD1_k127_1010890_1 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 462.0
HKD1_k127_1010890_11 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0003876 53.0
HKD1_k127_1010890_2 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 310.0
HKD1_k127_1010890_3 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001354 261.0
HKD1_k127_1010890_4 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000007281 192.0
HKD1_k127_1010890_5 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000001655 175.0
HKD1_k127_1010890_6 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000001111 160.0
HKD1_k127_1010890_8 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000005273 87.0
HKD1_k127_1010890_9 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.0000000003832 70.0
HKD1_k127_1029062_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 3.672e-217 696.0
HKD1_k127_1029062_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 575.0
HKD1_k127_1029062_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 557.0
HKD1_k127_1029062_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009581 259.0
HKD1_k127_1029062_4 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000003991 231.0
HKD1_k127_1029062_5 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000002076 206.0
HKD1_k127_1124413_0 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000002477 149.0
HKD1_k127_1140906_0 Amino acid permease - - - 8.634e-204 655.0
HKD1_k127_1140906_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 565.0
HKD1_k127_1140906_10 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000493 289.0
HKD1_k127_1140906_11 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001875 291.0
HKD1_k127_1140906_12 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
HKD1_k127_1140906_13 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001966 276.0
HKD1_k127_1140906_14 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001461 259.0
HKD1_k127_1140906_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 243.0
HKD1_k127_1140906_16 Ferritin-like domain - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
HKD1_k127_1140906_17 Extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000001405 230.0
HKD1_k127_1140906_18 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000005448 232.0
HKD1_k127_1140906_19 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000002361 225.0
HKD1_k127_1140906_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 461.0
HKD1_k127_1140906_20 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000001311 224.0
HKD1_k127_1140906_21 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000202 209.0
HKD1_k127_1140906_22 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000028 219.0
HKD1_k127_1140906_23 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000005229 209.0
HKD1_k127_1140906_24 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000001301 202.0
HKD1_k127_1140906_25 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000003543 174.0
HKD1_k127_1140906_26 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.0000000000000000000000000000000000000000000131 175.0
HKD1_k127_1140906_27 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.0000000000000000000000000000000000000000001652 184.0
HKD1_k127_1140906_28 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000008473 165.0
HKD1_k127_1140906_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000002441 157.0
HKD1_k127_1140906_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 446.0
HKD1_k127_1140906_30 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000001254 148.0
HKD1_k127_1140906_31 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000183 143.0
HKD1_k127_1140906_32 Thioesterase superfamily - - - 0.00000000000000000000000000000002045 134.0
HKD1_k127_1140906_33 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000003801 117.0
HKD1_k127_1140906_34 Papain-like cysteine protease AvrRpt2 - - - 0.00000000000000000000001413 113.0
HKD1_k127_1140906_35 Transcriptional regulator - - - 0.0000000000000000000001208 103.0
HKD1_k127_1140906_36 Tetratricopeptide repeat - - - 0.00000000000000000001916 104.0
HKD1_k127_1140906_37 Cytochrome c554 and c-prime - - - 0.000000000000000000292 94.0
HKD1_k127_1140906_38 Thioesterase K01075 - 3.1.2.23 0.000000000000000004838 97.0
HKD1_k127_1140906_39 Ferric uptake regulator family K03711 - - 0.000000000000008342 87.0
HKD1_k127_1140906_4 PFAM Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 425.0
HKD1_k127_1140906_40 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000004039 76.0
HKD1_k127_1140906_41 - - - - 0.0000000000002658 76.0
HKD1_k127_1140906_42 Sulfurtransferase TusA K04085 - - 0.0000000003967 63.0
HKD1_k127_1140906_43 - K07245 - - 0.000000686 59.0
HKD1_k127_1140906_45 Putative zinc-finger - - - 0.00007752 54.0
HKD1_k127_1140906_46 Conserved hypothetical protein 95 - - - 0.000715 50.0
HKD1_k127_1140906_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 396.0
HKD1_k127_1140906_6 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 375.0
HKD1_k127_1140906_7 Molybdenum Cofactor Synthesis C K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 308.0
HKD1_k127_1140906_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 302.0
HKD1_k127_1140906_9 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 302.0
HKD1_k127_12887_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.722e-299 927.0
HKD1_k127_12887_1 DNA polymerase K02347 - - 1.042e-212 676.0
HKD1_k127_12887_10 electron transport K00196,K05796 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000001627 149.0
HKD1_k127_12887_11 RDD family - - - 0.00000000000000000000000000000000008243 144.0
HKD1_k127_12887_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529,K18249 - 1.18.1.3 0.000000000000000000000001241 122.0
HKD1_k127_12887_13 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000002161 97.0
HKD1_k127_12887_14 domain protein K20276 - - 0.00000000000002563 87.0
HKD1_k127_12887_2 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 4.917e-212 676.0
HKD1_k127_12887_3 PFAM Xanthine uracil vitamin C permease K06901 - - 8.422e-195 616.0
HKD1_k127_12887_4 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 567.0
HKD1_k127_12887_5 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 421.0
HKD1_k127_12887_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 318.0
HKD1_k127_12887_7 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
HKD1_k127_12887_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000003352 223.0
HKD1_k127_12887_9 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000002829 200.0
HKD1_k127_1306070_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 475.0
HKD1_k127_1306070_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
HKD1_k127_1306070_2 Predicted permease - - - 0.000000000000000000000000000000000000000000000000003453 194.0
HKD1_k127_1306070_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000003053 186.0
HKD1_k127_1306070_4 - - - - 0.000000000000000000000000000000000000000001039 171.0
HKD1_k127_1306070_5 Right handed beta helix region - - - 0.0000005826 63.0
HKD1_k127_1306070_6 HEAT repeat - - - 0.000004404 50.0
HKD1_k127_1320171_0 carbamoyl transferase, NodU family K00612 - - 1.175e-299 929.0
HKD1_k127_1320171_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 528.0
HKD1_k127_1320171_10 - - - - 0.00000000000002491 80.0
HKD1_k127_1320171_11 transcription activator, effector binding - - - 0.00000134 57.0
HKD1_k127_1320171_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 347.0
HKD1_k127_1320171_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 315.0
HKD1_k127_1320171_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 297.0
HKD1_k127_1320171_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 292.0
HKD1_k127_1320171_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000009427 198.0
HKD1_k127_1320171_7 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000005565 125.0
HKD1_k127_1320171_8 nodulation - - - 0.0000000000000000000000000001101 124.0
HKD1_k127_1320171_9 SURF4 family K15977 - - 0.000000000000000000000000003116 115.0
HKD1_k127_1321374_0 PFAM Type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 440.0
HKD1_k127_1321374_1 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000006761 197.0
HKD1_k127_1321374_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000001103 157.0
HKD1_k127_1321374_3 Type II secretion system protein F domain-containing protein 1 K12510 - - 0.000000000000000000000002648 115.0
HKD1_k127_1321374_4 flp pilus assembly protein CpaB K02279 - - 0.00000000000000003053 93.0
HKD1_k127_1321374_5 PFAM type II secretion system protein K12511 - - 0.00000000000269 77.0
HKD1_k127_1327435_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.074e-275 859.0
HKD1_k127_1327435_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 578.0
HKD1_k127_1327435_10 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000008938 198.0
HKD1_k127_1327435_11 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000003126 196.0
HKD1_k127_1327435_12 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000001839 203.0
HKD1_k127_1327435_13 YbbR-like protein - - - 0.000000000000000000000000000002811 136.0
HKD1_k127_1327435_14 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000000008641 123.0
HKD1_k127_1327435_15 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001825 107.0
HKD1_k127_1327435_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 574.0
HKD1_k127_1327435_3 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 562.0
HKD1_k127_1327435_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 424.0
HKD1_k127_1327435_5 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 387.0
HKD1_k127_1327435_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 296.0
HKD1_k127_1327435_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006739 275.0
HKD1_k127_1327435_8 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001204 225.0
HKD1_k127_1327435_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000003629 216.0
HKD1_k127_1359333_0 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 390.0
HKD1_k127_1359333_1 Phage integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 384.0
HKD1_k127_1359333_2 Binding-protein-dependent transport system inner membrane component K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
HKD1_k127_1359333_3 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 340.0
HKD1_k127_1359333_4 Binding-protein-dependent transport system inner membrane component K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 306.0
HKD1_k127_1406662_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1247.0
HKD1_k127_1406662_1 Belongs to the peptidase M16 family K07263 - - 1.515e-304 960.0
HKD1_k127_1406662_10 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 441.0
HKD1_k127_1406662_11 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 425.0
HKD1_k127_1406662_12 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 423.0
HKD1_k127_1406662_13 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 439.0
HKD1_k127_1406662_14 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 429.0
HKD1_k127_1406662_15 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 404.0
HKD1_k127_1406662_16 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 405.0
HKD1_k127_1406662_17 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 423.0
HKD1_k127_1406662_18 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 386.0
HKD1_k127_1406662_19 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
HKD1_k127_1406662_2 CBS domain containing protein K00974 - 2.7.7.72 6.129e-262 835.0
HKD1_k127_1406662_20 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 376.0
HKD1_k127_1406662_21 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 355.0
HKD1_k127_1406662_22 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HKD1_k127_1406662_23 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 343.0
HKD1_k127_1406662_24 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 337.0
HKD1_k127_1406662_25 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 327.0
HKD1_k127_1406662_26 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 310.0
HKD1_k127_1406662_27 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 299.0
HKD1_k127_1406662_28 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002632 283.0
HKD1_k127_1406662_29 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002775 293.0
HKD1_k127_1406662_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.026e-236 758.0
HKD1_k127_1406662_30 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003073 302.0
HKD1_k127_1406662_31 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 281.0
HKD1_k127_1406662_32 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000002006 276.0
HKD1_k127_1406662_33 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009387 263.0
HKD1_k127_1406662_34 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
HKD1_k127_1406662_35 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000101 219.0
HKD1_k127_1406662_36 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000008504 221.0
HKD1_k127_1406662_37 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000002502 229.0
HKD1_k127_1406662_38 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000004583 211.0
HKD1_k127_1406662_39 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000001371 214.0
HKD1_k127_1406662_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 604.0
HKD1_k127_1406662_40 Virulence activator alpha C-term - - - 0.000000000000000000000000000000000000000000000000000002672 196.0
HKD1_k127_1406662_41 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000007597 209.0
HKD1_k127_1406662_42 - - - - 0.0000000000000000000000000000000000000000000001165 177.0
HKD1_k127_1406662_43 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000002588 175.0
HKD1_k127_1406662_44 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000000352 173.0
HKD1_k127_1406662_45 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000002916 171.0
HKD1_k127_1406662_46 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000001966 138.0
HKD1_k127_1406662_47 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000008807 140.0
HKD1_k127_1406662_48 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000005309 130.0
HKD1_k127_1406662_49 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000006302 121.0
HKD1_k127_1406662_5 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 565.0
HKD1_k127_1406662_50 mRNA binding - - - 0.0000000000000000000000000002722 114.0
HKD1_k127_1406662_51 transport - - - 0.000000000000000000000004284 115.0
HKD1_k127_1406662_52 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001973 91.0
HKD1_k127_1406662_53 GYD domain - - - 0.0000000000000000003364 93.0
HKD1_k127_1406662_54 - - - - 0.00000000000001639 78.0
HKD1_k127_1406662_55 Bacteriophage replication gene A protein (GPA) - - - 0.000000005044 58.0
HKD1_k127_1406662_57 - - - - 0.0000009634 57.0
HKD1_k127_1406662_6 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 570.0
HKD1_k127_1406662_60 denitrification pathway - - - 0.0005504 49.0
HKD1_k127_1406662_61 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0009008 48.0
HKD1_k127_1406662_7 Domain of unknown function(DUF2779) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 520.0
HKD1_k127_1406662_8 Xaa-His dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 499.0
HKD1_k127_1406662_9 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 451.0
HKD1_k127_1413980_0 Large extracellular alpha-helical protein K06894 - - 0.0 2082.0
HKD1_k127_1413980_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.1e-322 1001.0
HKD1_k127_1413980_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 315.0
HKD1_k127_1413980_3 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
HKD1_k127_1413980_4 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000002623 213.0
HKD1_k127_1413980_5 - - - - 0.00000000000000000000000000000000000000004399 159.0
HKD1_k127_1413980_6 Metal-dependent hydrolases of the beta-lactamase superfamily I K00784 - 3.1.26.11 0.000000000000000000000000000000009255 138.0
HKD1_k127_1413980_7 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000004328 134.0
HKD1_k127_1413980_8 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000239 115.0
HKD1_k127_1421095_0 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 331.0
HKD1_k127_1421095_1 HEAT repeats - - - 0.000000000000000000000000000000000001438 156.0
HKD1_k127_1421095_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000188 139.0
HKD1_k127_1421095_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000001225 132.0
HKD1_k127_1421095_4 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000002043 105.0
HKD1_k127_1421095_5 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000004138 102.0
HKD1_k127_1462158_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.241e-230 728.0
HKD1_k127_1462158_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 5.421e-202 652.0
HKD1_k127_1462158_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000002909 145.0
HKD1_k127_1462158_11 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000008047 109.0
HKD1_k127_1462158_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000001106 99.0
HKD1_k127_1462158_13 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000001555 97.0
HKD1_k127_1462158_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 565.0
HKD1_k127_1462158_3 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
HKD1_k127_1462158_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 465.0
HKD1_k127_1462158_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
HKD1_k127_1462158_6 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000002288 211.0
HKD1_k127_1462158_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000001411 198.0
HKD1_k127_1462158_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000215 196.0
HKD1_k127_1462158_9 - - - - 0.000000000000000000000000000000000000000000002326 180.0
HKD1_k127_1464754_0 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.748e-255 809.0
HKD1_k127_1464754_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 1.096e-209 685.0
HKD1_k127_1464754_2 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005776 284.0
HKD1_k127_1464754_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000008908 268.0
HKD1_k127_1464754_4 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000004966 198.0
HKD1_k127_1464754_5 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000261 117.0
HKD1_k127_1464754_6 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000009174 78.0
HKD1_k127_1464754_7 Hydrogenase nickel incorporation protein HypA K04651 - - 0.00000000001168 76.0
HKD1_k127_1508866_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1090.0
HKD1_k127_1508866_1 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 505.0
HKD1_k127_1508866_10 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000003776 153.0
HKD1_k127_1508866_11 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000009424 165.0
HKD1_k127_1508866_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000007302 153.0
HKD1_k127_1508866_13 - - - - 0.0000000000000000000000000000000004365 140.0
HKD1_k127_1508866_14 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000001122 134.0
HKD1_k127_1508866_15 response regulator - - - 0.000000000000000000000000000001232 138.0
HKD1_k127_1508866_16 Domain of unknown function (DUF1858) - - - 0.0000000000000000001147 90.0
HKD1_k127_1508866_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 439.0
HKD1_k127_1508866_3 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 395.0
HKD1_k127_1508866_4 Efflux ABC transporter permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 301.0
HKD1_k127_1508866_5 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
HKD1_k127_1508866_6 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000003145 252.0
HKD1_k127_1508866_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000006076 218.0
HKD1_k127_1508866_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000003315 193.0
HKD1_k127_1508866_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000001487 177.0
HKD1_k127_1538611_0 Belongs to the peptidase M16 family K07263 - - 0.0 1032.0
HKD1_k127_1538611_1 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 341.0
HKD1_k127_1538611_2 regulator of chromosome condensation, RCC1 - - - 0.000000000000005948 89.0
HKD1_k127_156406_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.014e-289 917.0
HKD1_k127_156406_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 597.0
HKD1_k127_156406_10 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000695 192.0
HKD1_k127_156406_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000000000000000000003694 174.0
HKD1_k127_156406_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000002072 160.0
HKD1_k127_156406_13 4Fe-4S binding domain - - - 0.000000000000000000000000000000000002375 142.0
HKD1_k127_156406_14 SNARE associated Golgi protein - - - 0.000000000000000000007447 105.0
HKD1_k127_156406_15 denitrification pathway - - - 0.00000000000000001351 91.0
HKD1_k127_156406_16 - - - - 0.00000000000003023 75.0
HKD1_k127_156406_17 heat shock protein binding K03686,K04082,K05516 - - 0.00000000000005019 76.0
HKD1_k127_156406_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 553.0
HKD1_k127_156406_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 542.0
HKD1_k127_156406_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 452.0
HKD1_k127_156406_5 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 362.0
HKD1_k127_156406_6 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 344.0
HKD1_k127_156406_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 347.0
HKD1_k127_156406_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 328.0
HKD1_k127_156406_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000003811 195.0
HKD1_k127_1599090_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 5.974e-228 721.0
HKD1_k127_1599090_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.255e-213 674.0
HKD1_k127_1599090_10 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 350.0
HKD1_k127_1599090_11 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 288.0
HKD1_k127_1599090_12 SMART chemotaxis sensory transducer K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004366 272.0
HKD1_k127_1599090_13 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006709 266.0
HKD1_k127_1599090_14 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
HKD1_k127_1599090_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000004508 242.0
HKD1_k127_1599090_16 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000002155 227.0
HKD1_k127_1599090_17 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000000000000000000000000000000000000002084 205.0
HKD1_k127_1599090_18 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000001903 200.0
HKD1_k127_1599090_19 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000008908 211.0
HKD1_k127_1599090_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 571.0
HKD1_k127_1599090_20 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000003146 200.0
HKD1_k127_1599090_21 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000001445 177.0
HKD1_k127_1599090_22 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000002404 175.0
HKD1_k127_1599090_23 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000001235 167.0
HKD1_k127_1599090_24 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000331 126.0
HKD1_k127_1599090_25 Tetratricopeptide repeat - - - 0.0001093 52.0
HKD1_k127_1599090_3 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 486.0
HKD1_k127_1599090_4 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 454.0
HKD1_k127_1599090_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 406.0
HKD1_k127_1599090_6 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 401.0
HKD1_k127_1599090_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 395.0
HKD1_k127_1599090_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 401.0
HKD1_k127_1599090_9 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 355.0
HKD1_k127_1600357_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 571.0
HKD1_k127_1600357_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000006788 273.0
HKD1_k127_1600357_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000002799 194.0
HKD1_k127_1600357_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000002352 187.0
HKD1_k127_1600357_4 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000001502 165.0
HKD1_k127_1600357_5 Protein of unknown function (DUF3108) - - - 0.000000000000000005525 94.0
HKD1_k127_1600357_6 Belongs to the UPF0434 family K09791 - - 0.0000000000000002142 79.0
HKD1_k127_1600357_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000001554 75.0
HKD1_k127_1610425_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1722.0
HKD1_k127_1610425_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 598.0
HKD1_k127_1610425_10 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 344.0
HKD1_k127_1610425_11 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 339.0
HKD1_k127_1610425_12 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 304.0
HKD1_k127_1610425_13 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006103 276.0
HKD1_k127_1610425_14 PFAM regulatory protein TetR K16137 - - 0.000000000000000000000000000000000000000000000000000000000006661 220.0
HKD1_k127_1610425_15 - - - - 0.000000000000000000000000000000000000000000000000000001619 196.0
HKD1_k127_1610425_16 - - - - 0.000000000000000000000000000000000000000000000000000009115 192.0
HKD1_k127_1610425_17 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000001016 190.0
HKD1_k127_1610425_18 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000009491 171.0
HKD1_k127_1610425_19 translation initiation factor activity K03646 - - 0.000000000000000000000000000000000000008155 149.0
HKD1_k127_1610425_2 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 566.0
HKD1_k127_1610425_20 trehalose biosynthetic process K01087 - 3.1.3.12 0.00000000000000000000000000000000006178 154.0
HKD1_k127_1610425_21 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000061 138.0
HKD1_k127_1610425_22 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000001325 114.0
HKD1_k127_1610425_23 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000004376 109.0
HKD1_k127_1610425_24 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000003284 111.0
HKD1_k127_1610425_25 redox-active disulfide protein 2 - - - 0.0000000000000000003644 89.0
HKD1_k127_1610425_27 - - - - 0.0000000000001242 78.0
HKD1_k127_1610425_28 transport system, periplasmic component - - - 0.000000000002866 66.0
HKD1_k127_1610425_29 MaoC like domain - - - 0.0009923 43.0
HKD1_k127_1610425_3 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 527.0
HKD1_k127_1610425_4 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 527.0
HKD1_k127_1610425_5 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 526.0
HKD1_k127_1610425_6 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 451.0
HKD1_k127_1610425_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 487.0
HKD1_k127_1610425_8 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 398.0
HKD1_k127_1610425_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 381.0
HKD1_k127_1624932_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.468e-286 890.0
HKD1_k127_1624932_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 536.0
HKD1_k127_1624932_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 394.0
HKD1_k127_1624932_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 372.0
HKD1_k127_1624932_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 348.0
HKD1_k127_1624932_5 DNA integration K14059 - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
HKD1_k127_1624932_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000002986 194.0
HKD1_k127_1653389_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.392e-233 728.0
HKD1_k127_1653389_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 8.343e-217 694.0
HKD1_k127_1653389_10 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 246.0
HKD1_k127_1653389_11 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000002794 237.0
HKD1_k127_1653389_12 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000008277 229.0
HKD1_k127_1653389_13 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000002418 193.0
HKD1_k127_1653389_14 AAA domain K07321 - - 0.00000000000000000000000000000000000000000001447 183.0
HKD1_k127_1653389_15 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000008667 156.0
HKD1_k127_1653389_16 PFAM cytochrome c, class I K00406 - - 0.00000000000000000000000000000000006673 139.0
HKD1_k127_1653389_17 FixH - - - 0.000000000000000765 91.0
HKD1_k127_1653389_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 589.0
HKD1_k127_1653389_3 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 513.0
HKD1_k127_1653389_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 378.0
HKD1_k127_1653389_5 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 351.0
HKD1_k127_1653389_6 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 349.0
HKD1_k127_1653389_7 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 324.0
HKD1_k127_1653389_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 348.0
HKD1_k127_1653389_9 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001964 268.0
HKD1_k127_1654865_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1540.0
HKD1_k127_1654865_1 Sugar (and other) transporter K03446 - - 1.331e-197 629.0
HKD1_k127_1654865_10 lysyl-tRNA synthetase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000001609 233.0
HKD1_k127_1654865_11 Transcriptional regulator K18136 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001482 217.0
HKD1_k127_1654865_12 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000000000000000000000000000000000001392 218.0
HKD1_k127_1654865_13 carbonate dehydratase activity - - - 0.00000000000000000000000000000000000000000002101 170.0
HKD1_k127_1654865_14 GYD domain - - - 0.000000000000000000000000000000000004345 141.0
HKD1_k127_1654865_15 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000264 139.0
HKD1_k127_1654865_16 protein with SCP PR1 domains - - - 0.000000000000000000000000002442 119.0
HKD1_k127_1654865_17 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000003326 109.0
HKD1_k127_1654865_18 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000002021 80.0
HKD1_k127_1654865_19 Thioesterase superfamily K02614 - - 0.0000000000006958 75.0
HKD1_k127_1654865_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 569.0
HKD1_k127_1654865_20 Amidohydrolase K07045 - - 0.0000000000009241 82.0
HKD1_k127_1654865_21 - - - - 0.000005096 55.0
HKD1_k127_1654865_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 472.0
HKD1_k127_1654865_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 447.0
HKD1_k127_1654865_5 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 366.0
HKD1_k127_1654865_6 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 330.0
HKD1_k127_1654865_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 296.0
HKD1_k127_1654865_8 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 302.0
HKD1_k127_1654865_9 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003355 291.0
HKD1_k127_1779865_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1188.0
HKD1_k127_1779865_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1013.0
HKD1_k127_1779865_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 306.0
HKD1_k127_1779865_11 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000001242 261.0
HKD1_k127_1779865_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000001498 238.0
HKD1_k127_1779865_13 PFAM Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000333 233.0
HKD1_k127_1779865_14 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000005538 207.0
HKD1_k127_1779865_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000003881 145.0
HKD1_k127_1779865_16 Universal stress protein K06149 - - 0.0000000000000000000000000000000000002542 146.0
HKD1_k127_1779865_17 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000006647 131.0
HKD1_k127_1779865_18 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000001483 147.0
HKD1_k127_1779865_19 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000002458 109.0
HKD1_k127_1779865_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.561e-259 813.0
HKD1_k127_1779865_20 Putative regulatory protein - - - 0.00000000000000000002871 95.0
HKD1_k127_1779865_21 Protein of unknown function (DUF507) - - - 0.0000000000000002093 86.0
HKD1_k127_1779865_23 TonB C terminal K03832 - - 0.00000001208 66.0
HKD1_k127_1779865_24 Protein of unknown function (DUF507) - - - 0.00000006743 64.0
HKD1_k127_1779865_25 Saccharopine dehydrogenase K12445 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00007076 54.0
HKD1_k127_1779865_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
HKD1_k127_1779865_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 606.0
HKD1_k127_1779865_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 593.0
HKD1_k127_1779865_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 536.0
HKD1_k127_1779865_7 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 465.0
HKD1_k127_1779865_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 377.0
HKD1_k127_1779865_9 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 312.0
HKD1_k127_1903643_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1105.0
HKD1_k127_1903643_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 497.0
HKD1_k127_1903643_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000004629 164.0
HKD1_k127_1903643_11 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000007198 146.0
HKD1_k127_1903643_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001491 147.0
HKD1_k127_1903643_13 SpoVG K06412 - - 0.0000000000000000000000000000002149 125.0
HKD1_k127_1903643_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000004985 125.0
HKD1_k127_1903643_16 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001596 102.0
HKD1_k127_1903643_17 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000003226 90.0
HKD1_k127_1903643_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 427.0
HKD1_k127_1903643_3 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 402.0
HKD1_k127_1903643_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003535 267.0
HKD1_k127_1903643_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 253.0
HKD1_k127_1903643_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000009816 199.0
HKD1_k127_1903643_7 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003844 202.0
HKD1_k127_1903643_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000002025 173.0
HKD1_k127_1903643_9 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000007605 155.0
HKD1_k127_1915826_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 616.0
HKD1_k127_1915826_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 539.0
HKD1_k127_1915826_10 pfam abc K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009974 273.0
HKD1_k127_1915826_11 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005998 250.0
HKD1_k127_1915826_12 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000007749 195.0
HKD1_k127_1915826_13 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000002565 165.0
HKD1_k127_1915826_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000001202 145.0
HKD1_k127_1915826_15 PFAM Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000008281 155.0
HKD1_k127_1915826_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000002892 139.0
HKD1_k127_1915826_17 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000003572 123.0
HKD1_k127_1915826_18 Rubrerythrin - - - 0.00000000000000008707 89.0
HKD1_k127_1915826_19 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000002581 89.0
HKD1_k127_1915826_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 524.0
HKD1_k127_1915826_20 cobalt ion transport K02009 - - 0.00000000000002127 86.0
HKD1_k127_1915826_21 Rubrerythrin - - - 0.0000000000003433 69.0
HKD1_k127_1915826_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000003752 66.0
HKD1_k127_1915826_23 Membrane - - - 0.00007225 51.0
HKD1_k127_1915826_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 488.0
HKD1_k127_1915826_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 428.0
HKD1_k127_1915826_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 413.0
HKD1_k127_1915826_6 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 349.0
HKD1_k127_1915826_7 Histidine kinase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 349.0
HKD1_k127_1915826_8 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HKD1_k127_1915826_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003928 277.0
HKD1_k127_1943691_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 277.0
HKD1_k127_1943691_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000005541 195.0
HKD1_k127_1943691_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000001075 180.0
HKD1_k127_1943691_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000001236 158.0
HKD1_k127_1943691_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000006875 135.0
HKD1_k127_1943691_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004708 69.0
HKD1_k127_1943691_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0003438 43.0
HKD1_k127_196352_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.0 1066.0
HKD1_k127_196352_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.643e-237 751.0
HKD1_k127_196352_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000003718 72.0
HKD1_k127_196352_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 379.0
HKD1_k127_196352_3 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000001222 217.0
HKD1_k127_196352_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000004374 214.0
HKD1_k127_196352_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000002027 217.0
HKD1_k127_196352_6 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000003893 194.0
HKD1_k127_196352_7 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000001272 157.0
HKD1_k127_196352_8 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000678 152.0
HKD1_k127_196352_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000009435 75.0
HKD1_k127_2007507_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1339.0
HKD1_k127_2007507_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 1.302e-269 852.0
HKD1_k127_2007507_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001683 279.0
HKD1_k127_2007507_11 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000009198 225.0
HKD1_k127_2007507_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000001942 215.0
HKD1_k127_2007507_13 Membrane - - - 0.00000000000000000000000000000001975 135.0
HKD1_k127_2007507_14 catechol 2,3-dioxygenase activity - - - 0.00000000000000000000000000001344 124.0
HKD1_k127_2007507_15 Nucleoside recognition - - - 0.0000000000000000000000000001449 122.0
HKD1_k127_2007507_16 Nucleoside recognition - - - 0.0000000000000000000000000003591 125.0
HKD1_k127_2007507_17 - - - - 0.00000000000000000000000271 118.0
HKD1_k127_2007507_18 Domain of unknown function DUF302 K12308 - 3.2.1.23 0.00000000000000000000006617 104.0
HKD1_k127_2007507_19 Protein of unknown function (DUF2892) - - - 0.0000000000000000004806 89.0
HKD1_k127_2007507_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 6.182e-221 691.0
HKD1_k127_2007507_21 Regulatory protein, FmdB - - - 0.0000003972 54.0
HKD1_k127_2007507_22 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00002976 46.0
HKD1_k127_2007507_3 Belongs to the peptidase M16 family K07263 - - 1.116e-200 656.0
HKD1_k127_2007507_4 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 498.0
HKD1_k127_2007507_5 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 492.0
HKD1_k127_2007507_6 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 389.0
HKD1_k127_2007507_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 351.0
HKD1_k127_2007507_8 Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 326.0
HKD1_k127_2007507_9 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
HKD1_k127_2033428_0 Transketolase, thiamine diphosphate binding domain K01662 - 2.2.1.7 1.803e-282 896.0
HKD1_k127_2033428_1 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 5.299e-281 878.0
HKD1_k127_2033428_10 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 458.0
HKD1_k127_2033428_11 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 447.0
HKD1_k127_2033428_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 443.0
HKD1_k127_2033428_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 434.0
HKD1_k127_2033428_14 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 396.0
HKD1_k127_2033428_15 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 395.0
HKD1_k127_2033428_16 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 383.0
HKD1_k127_2033428_17 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
HKD1_k127_2033428_18 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 387.0
HKD1_k127_2033428_19 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 353.0
HKD1_k127_2033428_2 Radical SAM - - - 8.075e-219 688.0
HKD1_k127_2033428_20 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 364.0
HKD1_k127_2033428_21 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 344.0
HKD1_k127_2033428_22 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 339.0
HKD1_k127_2033428_23 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 306.0
HKD1_k127_2033428_24 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 322.0
HKD1_k127_2033428_25 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 314.0
HKD1_k127_2033428_26 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 320.0
HKD1_k127_2033428_27 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 291.0
HKD1_k127_2033428_28 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 301.0
HKD1_k127_2033428_29 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001237 258.0
HKD1_k127_2033428_3 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 9.994e-211 670.0
HKD1_k127_2033428_30 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000006824 257.0
HKD1_k127_2033428_31 YdjC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000002081 240.0
HKD1_k127_2033428_32 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000001905 235.0
HKD1_k127_2033428_33 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000004399 192.0
HKD1_k127_2033428_34 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000001076 194.0
HKD1_k127_2033428_35 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000002759 197.0
HKD1_k127_2033428_36 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001578 159.0
HKD1_k127_2033428_37 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000001737 143.0
HKD1_k127_2033428_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000002739 144.0
HKD1_k127_2033428_39 Phosphorylase superfamily - - - 0.000000000000000000000000003502 120.0
HKD1_k127_2033428_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.639e-201 633.0
HKD1_k127_2033428_40 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000007374 94.0
HKD1_k127_2033428_41 CAAX protease self-immunity K07052 - - 0.000000000002257 75.0
HKD1_k127_2033428_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 625.0
HKD1_k127_2033428_6 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 546.0
HKD1_k127_2033428_7 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 494.0
HKD1_k127_2033428_8 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 490.0
HKD1_k127_2033428_9 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 485.0
HKD1_k127_2045068_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.85e-217 685.0
HKD1_k127_2045068_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
HKD1_k127_2045068_2 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
HKD1_k127_2045068_3 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000001322 225.0
HKD1_k127_2093548_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.303e-313 989.0
HKD1_k127_2093548_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 9.143e-282 888.0
HKD1_k127_2093548_10 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 312.0
HKD1_k127_2093548_11 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 310.0
HKD1_k127_2093548_12 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002567 311.0
HKD1_k127_2093548_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001578 291.0
HKD1_k127_2093548_14 PFAM Flavin reductase-like, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 271.0
HKD1_k127_2093548_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003222 280.0
HKD1_k127_2093548_16 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003086 259.0
HKD1_k127_2093548_17 PFAM ParB domain protein nuclease K03497 - - 0.00000000000000000000000000000000000000000000000000000000000002688 241.0
HKD1_k127_2093548_18 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000005566 209.0
HKD1_k127_2093548_19 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000009793 203.0
HKD1_k127_2093548_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.086e-248 785.0
HKD1_k127_2093548_20 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000001049 189.0
HKD1_k127_2093548_22 including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000003129 132.0
HKD1_k127_2093548_23 Domain of unknown function (DUF4034) - - - 0.000000000000000000000000000007044 135.0
HKD1_k127_2093548_24 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000004197 118.0
HKD1_k127_2093548_25 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000003375 91.0
HKD1_k127_2093548_26 Protein of unknown function (DUF3467) - - - 0.0000000000000002133 84.0
HKD1_k127_2093548_27 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000007618 75.0
HKD1_k127_2093548_28 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001281 66.0
HKD1_k127_2093548_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 534.0
HKD1_k127_2093548_4 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 485.0
HKD1_k127_2093548_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 483.0
HKD1_k127_2093548_6 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 409.0
HKD1_k127_2093548_7 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 352.0
HKD1_k127_2093548_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 352.0
HKD1_k127_2093548_9 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 340.0
HKD1_k127_2098400_0 Conserved carboxylase domain K01958 - 6.4.1.1 5.995e-223 711.0
HKD1_k127_2098400_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 545.0
HKD1_k127_2098400_10 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002909 257.0
HKD1_k127_2098400_11 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001121 262.0
HKD1_k127_2098400_12 methionine biosynthesis protein (MetW) - - - 0.000000000000000000000000000000000000000000000000000000000003173 230.0
HKD1_k127_2098400_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000001847 196.0
HKD1_k127_2098400_14 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000006526 163.0
HKD1_k127_2098400_15 NUDIX domain - - - 0.000000000000000000000000000001226 138.0
HKD1_k127_2098400_16 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000009022 123.0
HKD1_k127_2098400_17 Thioredoxin-like - - - 0.000000000000000005202 97.0
HKD1_k127_2098400_18 Belongs to the ParA family K04562 - - 0.0000005297 56.0
HKD1_k127_2098400_19 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.000001665 54.0
HKD1_k127_2098400_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 516.0
HKD1_k127_2098400_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 507.0
HKD1_k127_2098400_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 506.0
HKD1_k127_2098400_5 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 479.0
HKD1_k127_2098400_6 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 376.0
HKD1_k127_2098400_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 367.0
HKD1_k127_2098400_8 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 385.0
HKD1_k127_2098400_9 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 361.0
HKD1_k127_2120714_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.287e-248 788.0
HKD1_k127_2120714_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 606.0
HKD1_k127_2120714_10 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 385.0
HKD1_k127_2120714_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 363.0
HKD1_k127_2120714_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
HKD1_k127_2120714_13 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 311.0
HKD1_k127_2120714_14 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 292.0
HKD1_k127_2120714_15 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 291.0
HKD1_k127_2120714_16 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001305 285.0
HKD1_k127_2120714_17 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
HKD1_k127_2120714_18 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000008264 247.0
HKD1_k127_2120714_19 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000000001679 198.0
HKD1_k127_2120714_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 602.0
HKD1_k127_2120714_20 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000001062 194.0
HKD1_k127_2120714_21 Biotin-requiring enzyme - - - 0.0000000000000000000000000001152 123.0
HKD1_k127_2120714_22 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000001509 121.0
HKD1_k127_2120714_23 SMART Tetratricopeptide - - - 0.00000000000000000000000004242 120.0
HKD1_k127_2120714_24 ADP-ribosylglycohydrolase - - - 0.0000000000005247 82.0
HKD1_k127_2120714_3 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 551.0
HKD1_k127_2120714_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 559.0
HKD1_k127_2120714_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 552.0
HKD1_k127_2120714_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 533.0
HKD1_k127_2120714_7 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 479.0
HKD1_k127_2120714_8 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 460.0
HKD1_k127_2120714_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 382.0
HKD1_k127_2150316_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 523.0
HKD1_k127_2150316_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 472.0
HKD1_k127_2150316_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 445.0
HKD1_k127_2150316_3 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 438.0
HKD1_k127_2150316_4 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 443.0
HKD1_k127_2150316_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 378.0
HKD1_k127_2150316_6 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 287.0
HKD1_k127_2150316_7 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000008734 251.0
HKD1_k127_2161968_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.546e-310 976.0
HKD1_k127_2161968_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 521.0
HKD1_k127_2161968_10 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000123 286.0
HKD1_k127_2161968_11 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006379 289.0
HKD1_k127_2161968_12 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001726 280.0
HKD1_k127_2161968_13 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002711 260.0
HKD1_k127_2161968_14 SMART CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002056 248.0
HKD1_k127_2161968_15 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003264 239.0
HKD1_k127_2161968_16 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000002238 231.0
HKD1_k127_2161968_17 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000002627 204.0
HKD1_k127_2161968_18 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000004651 207.0
HKD1_k127_2161968_19 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000002652 210.0
HKD1_k127_2161968_2 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 490.0
HKD1_k127_2161968_20 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000001795 185.0
HKD1_k127_2161968_21 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000007434 155.0
HKD1_k127_2161968_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000001287 132.0
HKD1_k127_2161968_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000003742 69.0
HKD1_k127_2161968_24 PFAM Extracellular ligand-binding receptor K07121 - - 0.00002413 58.0
HKD1_k127_2161968_3 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 421.0
HKD1_k127_2161968_4 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
HKD1_k127_2161968_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 347.0
HKD1_k127_2161968_6 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 323.0
HKD1_k127_2161968_7 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 337.0
HKD1_k127_2161968_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
HKD1_k127_2161968_9 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 289.0
HKD1_k127_2172903_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.138e-230 761.0
HKD1_k127_2172903_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 444.0
HKD1_k127_2172903_10 Pfam:N_methyl_2 K02671 - - 0.0000000006081 67.0
HKD1_k127_2172903_11 OsmC-like protein - - - 0.000000008401 60.0
HKD1_k127_2172903_2 Histidine kinase K10715,K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 408.0
HKD1_k127_2172903_3 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 380.0
HKD1_k127_2172903_4 alcohol dehydrogenase K00001,K00002,K12957,K13953,K13979,K21190 GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008106,GO:0008150,GO:0008152,GO:0008270,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0030312,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071944 1.1.1.1,1.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 293.0
HKD1_k127_2172903_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006938 258.0
HKD1_k127_2172903_6 - - - - 0.00000000000000000003046 97.0
HKD1_k127_2172903_8 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000001063 83.0
HKD1_k127_2172903_9 - - - - 0.0000000000007469 76.0
HKD1_k127_2218358_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 460.0
HKD1_k127_2218358_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 436.0
HKD1_k127_2218358_2 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000000000000002495 126.0
HKD1_k127_2231637_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.854e-281 899.0
HKD1_k127_2231637_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.469e-249 781.0
HKD1_k127_2231637_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 346.0
HKD1_k127_2231637_11 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 319.0
HKD1_k127_2231637_12 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 295.0
HKD1_k127_2231637_13 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000068 274.0
HKD1_k127_2231637_14 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004814 259.0
HKD1_k127_2231637_15 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000001247 227.0
HKD1_k127_2231637_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000005145 246.0
HKD1_k127_2231637_17 N,N-dimethylaniline monooxygenase activity K07222 - - 0.000000000000000000000000000000000000000000000000008672 193.0
HKD1_k127_2231637_18 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000003286 176.0
HKD1_k127_2231637_19 Methyltransferase small domain protein - - - 0.00000000000000000000000000000000000000000000274 176.0
HKD1_k127_2231637_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 600.0
HKD1_k127_2231637_20 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000264 175.0
HKD1_k127_2231637_21 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000002838 167.0
HKD1_k127_2231637_22 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000005281 173.0
HKD1_k127_2231637_23 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000009727 160.0
HKD1_k127_2231637_24 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000000000000003496 173.0
HKD1_k127_2231637_25 metallopeptidase activity K03630 - - 0.000000000000000000000000000000000000007945 153.0
HKD1_k127_2231637_26 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000004519 153.0
HKD1_k127_2231637_27 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000109 138.0
HKD1_k127_2231637_28 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000008243 139.0
HKD1_k127_2231637_29 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000291 141.0
HKD1_k127_2231637_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 560.0
HKD1_k127_2231637_30 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000004634 136.0
HKD1_k127_2231637_31 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001591 128.0
HKD1_k127_2231637_32 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000007937 131.0
HKD1_k127_2231637_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000001013 139.0
HKD1_k127_2231637_34 Protein of unknown function DUF58 - - - 0.000000000000000000000000003243 130.0
HKD1_k127_2231637_35 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000003314 115.0
HKD1_k127_2231637_36 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000001064 111.0
HKD1_k127_2231637_37 Competence protein - - - 0.0000000000000000000002575 108.0
HKD1_k127_2231637_38 - - - - 0.000000000000004286 78.0
HKD1_k127_2231637_39 Protein of unknown function (DUF3343) - - - 0.0000000000001493 74.0
HKD1_k127_2231637_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 513.0
HKD1_k127_2231637_40 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000001007 82.0
HKD1_k127_2231637_41 Forkhead associated domain - - - 0.000000000008164 76.0
HKD1_k127_2231637_42 deoxyhypusine monooxygenase activity - - - 0.00000001515 67.0
HKD1_k127_2231637_43 deoxyhypusine monooxygenase activity - - - 0.00000006972 62.0
HKD1_k127_2231637_44 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.00002308 59.0
HKD1_k127_2231637_45 Protein of unknown function (DUF721) - - - 0.00002338 55.0
HKD1_k127_2231637_46 COG0457 FOG TPR repeat - - - 0.0005818 53.0
HKD1_k127_2231637_5 chelatase subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 435.0
HKD1_k127_2231637_6 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 387.0
HKD1_k127_2231637_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 387.0
HKD1_k127_2231637_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 371.0
HKD1_k127_2231637_9 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 341.0
HKD1_k127_2348852_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.966e-266 837.0
HKD1_k127_2348852_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 495.0
HKD1_k127_2348852_10 RNA-binding - - - 0.0000000000000000000000000000006629 124.0
HKD1_k127_2348852_11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000001192 121.0
HKD1_k127_2348852_14 thiolester hydrolase activity K06889 - - 0.00000000000007161 83.0
HKD1_k127_2348852_15 Domain of Unknown Function (DUF1259) - - - 0.0000001992 60.0
HKD1_k127_2348852_16 Heavy-metal resistance - - - 0.0004277 49.0
HKD1_k127_2348852_2 NAD+ diphosphatase activity K03426,K20449 - 1.3.7.1,3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 319.0
HKD1_k127_2348852_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 293.0
HKD1_k127_2348852_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HKD1_k127_2348852_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000004887 203.0
HKD1_k127_2348852_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000002077 191.0
HKD1_k127_2348852_7 - - - - 0.0000000000000000000000000000000000000000000000003179 179.0
HKD1_k127_2348852_8 DinB superfamily - - - 0.0000000000000000000000000000000000000000007591 163.0
HKD1_k127_2348852_9 Thiamine-binding protein - - - 0.00000000000000000000000000000000000001782 149.0
HKD1_k127_2350544_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 536.0
HKD1_k127_2350544_1 Protein of unknown function (DUF1698) - - - 0.00000000000000000000000000000000000000000000000000001277 201.0
HKD1_k127_2350544_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000004596 175.0
HKD1_k127_2350544_3 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000006888 169.0
HKD1_k127_2350544_4 peroxiredoxin activity - - - 0.00000000000000000000000000000000002534 141.0
HKD1_k127_2350544_5 PFAM Methyltransferase type 11 - - - 0.000000000000000005856 97.0
HKD1_k127_2350544_6 HEAT repeat - - - 0.000002129 60.0
HKD1_k127_2353097_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 316.0
HKD1_k127_2353097_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000065 190.0
HKD1_k127_2353097_2 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000001071 136.0
HKD1_k127_2353097_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000009111 135.0
HKD1_k127_2353097_4 cAMP biosynthetic process - - - 0.000000000000000000009092 108.0
HKD1_k127_2353097_5 Bacterial regulatory protein, Fis family - - - 0.00000000106 70.0
HKD1_k127_2353097_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000004852 53.0
HKD1_k127_2361349_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 466.0
HKD1_k127_2361349_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 369.0
HKD1_k127_2361349_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000004756 226.0
HKD1_k127_2361349_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000006487 97.0
HKD1_k127_2361894_0 GTP-binding protein TypA K06207 - - 3.379e-250 785.0
HKD1_k127_2361894_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 499.0
HKD1_k127_2361894_10 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000001866 172.0
HKD1_k127_2361894_11 TQO small subunit DoxD K15977 - - 0.000000000000000000000000000000000000005496 151.0
HKD1_k127_2361894_12 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000001764 159.0
HKD1_k127_2361894_13 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00006916 51.0
HKD1_k127_2361894_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 381.0
HKD1_k127_2361894_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 328.0
HKD1_k127_2361894_4 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001151 278.0
HKD1_k127_2361894_5 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006217 275.0
HKD1_k127_2361894_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002428 271.0
HKD1_k127_2361894_7 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003176 254.0
HKD1_k127_2361894_8 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001862 253.0
HKD1_k127_2361894_9 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000005511 209.0
HKD1_k127_2403533_0 B12 binding domain K00548 - 2.1.1.13 9.707e-318 999.0
HKD1_k127_2403533_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.196e-271 847.0
HKD1_k127_2403533_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000003694 126.0
HKD1_k127_2403533_3 Rubredoxin - - - 0.000000000000006522 90.0
HKD1_k127_2455644_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 593.0
HKD1_k127_2455644_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 352.0
HKD1_k127_2455644_10 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000005583 98.0
HKD1_k127_2455644_11 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000004877 81.0
HKD1_k127_2455644_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0001854 53.0
HKD1_k127_2455644_2 uridine phosphorylase activity K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
HKD1_k127_2455644_3 Pfam Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 321.0
HKD1_k127_2455644_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 296.0
HKD1_k127_2455644_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 278.0
HKD1_k127_2455644_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
HKD1_k127_2455644_7 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000002034 185.0
HKD1_k127_2455644_8 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000000000004944 149.0
HKD1_k127_2455644_9 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.0000000000000000000000000000000000007324 149.0
HKD1_k127_2555241_0 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 521.0
HKD1_k127_2555241_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 317.0
HKD1_k127_2555241_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000494 285.0
HKD1_k127_2555241_3 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001841 256.0
HKD1_k127_2555241_4 PFAM OmpA MotB domain protein - - - 0.00000000000000000000000000000000006678 153.0
HKD1_k127_2555241_5 FecR protein - - - 0.0000000000000000000000000000003912 129.0
HKD1_k127_2555241_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000001708 56.0
HKD1_k127_2555241_7 sigma-54 factor interaction domain-containing protein K02667 - - 0.00002712 53.0
HKD1_k127_2568164_0 FAD binding domain K05712 - 1.14.13.127 1.347e-203 661.0
HKD1_k127_2568164_1 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 597.0
HKD1_k127_2568164_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 396.0
HKD1_k127_2568164_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001658 251.0
HKD1_k127_2568164_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000001325 171.0
HKD1_k127_2568164_5 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000004388 168.0
HKD1_k127_2568164_6 Histidine kinase K00936 - 2.7.13.3 0.00000000000000000000000000000000001583 156.0
HKD1_k127_2568164_7 transcription factor binding - - - 0.0000000000000000000002702 113.0
HKD1_k127_2675409_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 2.141e-213 699.0
HKD1_k127_2675409_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 559.0
HKD1_k127_2675409_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003281 260.0
HKD1_k127_2675409_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00003213 57.0
HKD1_k127_2682633_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.051e-215 681.0
HKD1_k127_2682633_1 HlyD family secretion protein K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 368.0
HKD1_k127_2682633_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001122 239.0
HKD1_k127_2746916_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 599.0
HKD1_k127_2746916_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 511.0
HKD1_k127_2746916_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 420.0
HKD1_k127_2746916_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 317.0
HKD1_k127_2746916_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 312.0
HKD1_k127_2746916_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 302.0
HKD1_k127_2746916_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002348 263.0
HKD1_k127_2746916_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000004329 183.0
HKD1_k127_2746916_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000001752 149.0
HKD1_k127_2746916_9 outer membrane chaperone Skp (OmpH) K06142 - - 0.00000005899 65.0
HKD1_k127_3034448_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.746e-196 643.0
HKD1_k127_3034448_1 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 562.0
HKD1_k127_3034448_10 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000005647 229.0
HKD1_k127_3034448_11 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000007645 173.0
HKD1_k127_3034448_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001373 157.0
HKD1_k127_3034448_13 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000001228 164.0
HKD1_k127_3034448_14 cell redox homeostasis - - - 0.0000000000000000000000000000000000246 143.0
HKD1_k127_3034448_15 iron ion homeostasis - - - 0.0000000000000000000000000000000002633 151.0
HKD1_k127_3034448_16 PFAM DnaJ homologue, subfamily C, member 28, conserved domain - - - 0.000000000000000000000000000000000711 139.0
HKD1_k127_3034448_17 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000001904 115.0
HKD1_k127_3034448_18 - - - - 0.000000000000002731 81.0
HKD1_k127_3034448_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 502.0
HKD1_k127_3034448_20 - - - - 0.00000000000003399 82.0
HKD1_k127_3034448_21 RDD family - - - 0.0000000000008312 76.0
HKD1_k127_3034448_22 Putative zinc-finger - - - 0.0004876 49.0
HKD1_k127_3034448_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 505.0
HKD1_k127_3034448_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 459.0
HKD1_k127_3034448_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 457.0
HKD1_k127_3034448_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 350.0
HKD1_k127_3034448_7 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
HKD1_k127_3034448_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 308.0
HKD1_k127_3034448_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000923 250.0
HKD1_k127_304215_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 1.319e-281 888.0
HKD1_k127_304215_1 Translation-initiation factor 2 K02519 - - 1.85e-237 759.0
HKD1_k127_304215_10 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 426.0
HKD1_k127_304215_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 411.0
HKD1_k127_304215_12 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 401.0
HKD1_k127_304215_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 405.0
HKD1_k127_304215_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 400.0
HKD1_k127_304215_15 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 385.0
HKD1_k127_304215_16 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 397.0
HKD1_k127_304215_17 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 370.0
HKD1_k127_304215_18 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 359.0
HKD1_k127_304215_19 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 362.0
HKD1_k127_304215_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.537e-235 747.0
HKD1_k127_304215_20 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 317.0
HKD1_k127_304215_21 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 319.0
HKD1_k127_304215_22 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
HKD1_k127_304215_23 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 316.0
HKD1_k127_304215_24 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 299.0
HKD1_k127_304215_25 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 306.0
HKD1_k127_304215_26 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001125 273.0
HKD1_k127_304215_27 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
HKD1_k127_304215_28 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000006613 213.0
HKD1_k127_304215_29 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000001025 222.0
HKD1_k127_304215_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.404e-203 658.0
HKD1_k127_304215_30 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000003005 228.0
HKD1_k127_304215_31 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000001138 220.0
HKD1_k127_304215_32 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000007183 198.0
HKD1_k127_304215_33 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000002452 195.0
HKD1_k127_304215_34 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000005503 184.0
HKD1_k127_304215_35 Domain of unknown function (DUF4124) K08309 - - 0.0000000000000000000000000000000000000000000000005346 181.0
HKD1_k127_304215_36 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000002404 183.0
HKD1_k127_304215_37 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000001539 166.0
HKD1_k127_304215_38 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000002384 160.0
HKD1_k127_304215_39 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000002665 152.0
HKD1_k127_304215_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 644.0
HKD1_k127_304215_40 diguanylate cyclase - - - 0.000000000000000000000000000000000009347 153.0
HKD1_k127_304215_41 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006509 132.0
HKD1_k127_304215_42 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000003354 122.0
HKD1_k127_304215_43 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000001111 125.0
HKD1_k127_304215_44 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000007525 115.0
HKD1_k127_304215_45 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000002351 97.0
HKD1_k127_304215_46 Protein of unknown function (DUF503) K09764 - - 0.000000000001 74.0
HKD1_k127_304215_47 - - - - 0.000000000001649 76.0
HKD1_k127_304215_48 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.0000007763 58.0
HKD1_k127_304215_49 - - - - 0.0002383 48.0
HKD1_k127_304215_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 589.0
HKD1_k127_304215_6 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 592.0
HKD1_k127_304215_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 550.0
HKD1_k127_304215_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 510.0
HKD1_k127_304215_9 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 434.0
HKD1_k127_3070437_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 604.0
HKD1_k127_3070437_1 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 380.0
HKD1_k127_3070437_2 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 365.0
HKD1_k127_3070437_3 chain release factor K15034 - - 0.000000000000000000000000000000000000000000003147 167.0
HKD1_k127_3070437_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000001385 151.0
HKD1_k127_3070437_5 protein conserved in bacteria - - - 0.00000000000000000000000000003973 130.0
HKD1_k127_3070437_6 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000001258 118.0
HKD1_k127_3084333_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2004.0
HKD1_k127_3084333_1 Peptidase family M1 domain - - - 2.289e-210 675.0
HKD1_k127_3084333_10 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000009156 235.0
HKD1_k127_3084333_11 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001961 211.0
HKD1_k127_3084333_12 - - - - 0.0000000000000000000000000000000000000000000704 164.0
HKD1_k127_3084333_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000006673 136.0
HKD1_k127_3084333_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000003765 116.0
HKD1_k127_3084333_15 - - - - 0.00000000000000000000000117 109.0
HKD1_k127_3084333_16 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000000000000000309 100.0
HKD1_k127_3084333_18 - - - - 0.000000000000001074 80.0
HKD1_k127_3084333_19 - - - - 0.000000000000003742 86.0
HKD1_k127_3084333_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 576.0
HKD1_k127_3084333_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 519.0
HKD1_k127_3084333_4 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 379.0
HKD1_k127_3084333_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 332.0
HKD1_k127_3084333_6 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002858 298.0
HKD1_k127_3084333_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004568 269.0
HKD1_k127_3084333_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002899 236.0
HKD1_k127_3084333_9 serine-type endopeptidase activity K04771,K14949 - 2.7.11.1,3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000723 234.0
HKD1_k127_3117180_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1162.0
HKD1_k127_3117180_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.851e-255 800.0
HKD1_k127_3117180_10 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
HKD1_k127_3117180_11 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 312.0
HKD1_k127_3117180_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004867 290.0
HKD1_k127_3117180_13 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003863 264.0
HKD1_k127_3117180_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000001974 207.0
HKD1_k127_3117180_15 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000006246 176.0
HKD1_k127_3117180_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000009214 164.0
HKD1_k127_3117180_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000003102 143.0
HKD1_k127_3117180_18 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000001318 145.0
HKD1_k127_3117180_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000004559 136.0
HKD1_k127_3117180_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 5.234e-215 692.0
HKD1_k127_3117180_20 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000001217 128.0
HKD1_k127_3117180_21 Transcriptional regulator K13643 - - 0.000000000000000000000000002584 126.0
HKD1_k127_3117180_22 regulatory protein, MerR - - - 0.000000000000000000000648 102.0
HKD1_k127_3117180_23 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000001357 84.0
HKD1_k127_3117180_24 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000001328 65.0
HKD1_k127_3117180_25 ribonuclease BN - - - 0.000000003181 69.0
HKD1_k127_3117180_26 photosystem II stabilization K02237,K02238,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000007106 60.0
HKD1_k127_3117180_27 - - - - 0.00002397 49.0
HKD1_k127_3117180_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.229e-204 648.0
HKD1_k127_3117180_4 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 610.0
HKD1_k127_3117180_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 439.0
HKD1_k127_3117180_6 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 427.0
HKD1_k127_3117180_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 359.0
HKD1_k127_3117180_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 358.0
HKD1_k127_3117180_9 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 354.0
HKD1_k127_3138768_0 Glycosyl transferase family 21 K03669 - - 7.954e-230 741.0
HKD1_k127_3138768_1 periplasmic glucan biosynthesis protein K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 554.0
HKD1_k127_3138768_10 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000000000006918 102.0
HKD1_k127_3138768_11 MafB19-like deaminase - - - 0.0000000000000000002605 100.0
HKD1_k127_3138768_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 439.0
HKD1_k127_3138768_3 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 363.0
HKD1_k127_3138768_4 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 320.0
HKD1_k127_3138768_5 dienelactone hydrolase - - - 0.00000000000000000000000000000000001546 148.0
HKD1_k127_3138768_6 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000001227 147.0
HKD1_k127_3138768_7 - - - - 0.0000000000000000000000000000000005825 134.0
HKD1_k127_3138768_8 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000000000931 137.0
HKD1_k127_3138768_9 Cupin 2, conserved barrel - - - 0.0000000000000000000000004742 106.0
HKD1_k127_3152460_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.754e-246 783.0
HKD1_k127_3152460_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.676e-232 733.0
HKD1_k127_3152460_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 333.0
HKD1_k127_3152460_11 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003454 278.0
HKD1_k127_3152460_12 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000006712 247.0
HKD1_k127_3152460_13 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000001196 223.0
HKD1_k127_3152460_14 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000003346 188.0
HKD1_k127_3152460_15 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000000174 181.0
HKD1_k127_3152460_16 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000422 173.0
HKD1_k127_3152460_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000006393 179.0
HKD1_k127_3152460_18 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000002862 152.0
HKD1_k127_3152460_19 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000001907 146.0
HKD1_k127_3152460_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.829e-198 655.0
HKD1_k127_3152460_20 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000001075 123.0
HKD1_k127_3152460_21 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000003562 80.0
HKD1_k127_3152460_22 - - - - 0.0000000000001079 78.0
HKD1_k127_3152460_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000132 63.0
HKD1_k127_3152460_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000004968 62.0
HKD1_k127_3152460_25 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0005135 50.0
HKD1_k127_3152460_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 3.324e-195 627.0
HKD1_k127_3152460_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 592.0
HKD1_k127_3152460_5 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 490.0
HKD1_k127_3152460_6 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 488.0
HKD1_k127_3152460_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
HKD1_k127_3152460_8 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
HKD1_k127_3152460_9 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 353.0
HKD1_k127_3163872_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 424.0
HKD1_k127_3163872_1 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 323.0
HKD1_k127_3163872_2 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000001418 125.0
HKD1_k127_3163872_3 PFAM cytochrome c assembly protein - - - 0.00000000001793 67.0
HKD1_k127_316392_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.174e-284 898.0
HKD1_k127_316392_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.992e-210 676.0
HKD1_k127_316392_2 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 532.0
HKD1_k127_316392_3 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
HKD1_k127_316392_4 PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009244 242.0
HKD1_k127_316392_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000001826 202.0
HKD1_k127_316392_6 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000001154 163.0
HKD1_k127_316392_7 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00001401 47.0
HKD1_k127_3190262_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.0 1079.0
HKD1_k127_3190262_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 446.0
HKD1_k127_3190262_10 Histidine kinase - - - 0.0000000000000000000022 104.0
HKD1_k127_3190262_11 - - - - 0.00000000003168 72.0
HKD1_k127_3190262_12 glycosyl transferase family 8 - - - 0.000000007407 57.0
HKD1_k127_3190262_13 DNA excision K02806 - - 0.000228 46.0
HKD1_k127_3190262_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 414.0
HKD1_k127_3190262_3 Dimethylsulfoxide reductase chain B K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001984 245.0
HKD1_k127_3190262_4 DMSO reductase anchor subunit (DmsC) K07308 - - 0.0000000000000000000000000000000000000000000000000000000001948 222.0
HKD1_k127_3190262_5 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000009608 191.0
HKD1_k127_3190262_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000109 163.0
HKD1_k127_3190262_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000001777 145.0
HKD1_k127_3190262_8 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000003025 149.0
HKD1_k127_3190262_9 cell redox homeostasis - - - 0.0000000000000000000000002 113.0
HKD1_k127_3207481_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.816e-293 932.0
HKD1_k127_3207481_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 430.0
HKD1_k127_3207481_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
HKD1_k127_3207481_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000000003621 179.0
HKD1_k127_3207481_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000001403 170.0
HKD1_k127_3207481_5 YCII-related domain - - - 0.000000000000000000000000000000000000000000003829 168.0
HKD1_k127_3207481_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000003029 169.0
HKD1_k127_3207481_7 mannose-6-phosphate isomerase - - - 0.00000001073 60.0
HKD1_k127_322205_0 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 621.0
HKD1_k127_322205_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
HKD1_k127_322205_2 PFAM AIR synthase related protein K04655 - - 0.0000000000000000000000000000005693 138.0
HKD1_k127_322205_3 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000619 86.0
HKD1_k127_3223398_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.472e-218 720.0
HKD1_k127_3223398_1 CoA binding domain K01905,K22224 - 6.2.1.13 1.046e-196 633.0
HKD1_k127_3223398_10 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000002184 165.0
HKD1_k127_3223398_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000004015 147.0
HKD1_k127_3223398_12 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000005387 152.0
HKD1_k127_3223398_13 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000003997 105.0
HKD1_k127_3223398_14 SCP-2 sterol transfer family - - - 0.0000000000000000000001198 101.0
HKD1_k127_3223398_15 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000001243 116.0
HKD1_k127_3223398_2 ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 495.0
HKD1_k127_3223398_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
HKD1_k127_3223398_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
HKD1_k127_3223398_5 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 312.0
HKD1_k127_3223398_6 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000031 258.0
HKD1_k127_3223398_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000001096 214.0
HKD1_k127_3223398_8 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000004005 184.0
HKD1_k127_3223398_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000003892 167.0
HKD1_k127_3242803_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 565.0
HKD1_k127_3242803_1 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 400.0
HKD1_k127_3242803_10 Glucose / Sorbosone dehydrogenase K21430 - - 0.0003809 48.0
HKD1_k127_3242803_2 Phosphoadenosine phosphosulfate reductase family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 313.0
HKD1_k127_3242803_3 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000002427 252.0
HKD1_k127_3242803_4 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002886 252.0
HKD1_k127_3242803_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000001425 187.0
HKD1_k127_3242803_6 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000001424 73.0
HKD1_k127_3242803_7 thiamine diphosphate biosynthetic process K03154 - - 0.000000000000359 71.0
HKD1_k127_3242803_8 LUD domain K00782 - - 0.00000000001281 66.0
HKD1_k127_3242803_9 - - - - 0.00002869 54.0
HKD1_k127_327076_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 553.0
HKD1_k127_327076_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 358.0
HKD1_k127_327076_10 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000008785 116.0
HKD1_k127_327076_11 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000003992 76.0
HKD1_k127_327076_2 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 360.0
HKD1_k127_327076_3 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 287.0
HKD1_k127_327076_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000006678 256.0
HKD1_k127_327076_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000005583 212.0
HKD1_k127_327076_6 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000001611 196.0
HKD1_k127_327076_7 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000007499 185.0
HKD1_k127_327076_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000005158 175.0
HKD1_k127_327076_9 transglycosylase K08309 - - 0.0000000000000000000000000000001492 145.0
HKD1_k127_327233_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1121.0
HKD1_k127_327233_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.09e-202 646.0
HKD1_k127_327233_10 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000655 274.0
HKD1_k127_327233_11 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001547 265.0
HKD1_k127_327233_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000003556 199.0
HKD1_k127_327233_13 GAF domain - - - 0.000000000000000000000000000000000000000000000001929 192.0
HKD1_k127_327233_14 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000164 156.0
HKD1_k127_327233_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001205 106.0
HKD1_k127_327233_16 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000001087 75.0
HKD1_k127_327233_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 514.0
HKD1_k127_327233_3 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 471.0
HKD1_k127_327233_4 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 432.0
HKD1_k127_327233_5 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 441.0
HKD1_k127_327233_6 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 366.0
HKD1_k127_327233_7 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 312.0
HKD1_k127_327233_8 GTP cyclohydrolase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001327 286.0
HKD1_k127_327233_9 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002948 264.0
HKD1_k127_3275222_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 340.0
HKD1_k127_3275222_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 336.0
HKD1_k127_3275222_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000001053 217.0
HKD1_k127_3275222_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000003568 200.0
HKD1_k127_3275222_4 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000004402 198.0
HKD1_k127_3275222_5 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000000000000459 191.0
HKD1_k127_3275222_6 - - - - 0.000000000000000000000000000000001709 133.0
HKD1_k127_3275274_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 483.0
HKD1_k127_3275274_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 344.0
HKD1_k127_3275274_2 cheY-homologous receiver domain - - - 0.00000000000000000002214 98.0
HKD1_k127_3275274_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000007478 72.0
HKD1_k127_3275274_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000001102 68.0
HKD1_k127_3305698_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.674e-275 861.0
HKD1_k127_3305698_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 563.0
HKD1_k127_3305698_10 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000002145 74.0
HKD1_k127_3305698_2 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 514.0
HKD1_k127_3305698_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 470.0
HKD1_k127_3305698_4 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 409.0
HKD1_k127_3305698_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 297.0
HKD1_k127_3305698_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
HKD1_k127_3305698_7 - - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
HKD1_k127_3305698_8 SMART ATP-binding region ATPase domain protein K03406,K07710 - 2.7.13.3 0.00000000000000000000000000000000000003099 160.0
HKD1_k127_3305698_9 cheY-homologous receiver domain - - - 0.000000000000914 78.0
HKD1_k127_3308025_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.066e-239 767.0
HKD1_k127_3308025_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.7e-221 702.0
HKD1_k127_3308025_2 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 420.0
HKD1_k127_3308025_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 302.0
HKD1_k127_3308025_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000005513 134.0
HKD1_k127_3308025_5 domain, Protein - - - 0.00000000000000005571 89.0
HKD1_k127_3308025_6 Sodium/hydrogen exchanger family - - - 0.00000000001892 65.0
HKD1_k127_3400073_0 PFAM Aldehyde dehydrogenase - - - 5.449e-235 736.0
HKD1_k127_3400073_1 Receptor family ligand binding region K01999 - - 1.558e-209 659.0
HKD1_k127_3400073_10 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
HKD1_k127_3400073_11 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002425 284.0
HKD1_k127_3400073_12 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000002245 224.0
HKD1_k127_3400073_14 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000007441 142.0
HKD1_k127_3400073_15 PFAM Two component regulator propeller - - - 0.0000000000000000000000000002158 127.0
HKD1_k127_3400073_16 - - - - 0.0000000000000000000000003741 108.0
HKD1_k127_3400073_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 543.0
HKD1_k127_3400073_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 460.0
HKD1_k127_3400073_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 426.0
HKD1_k127_3400073_5 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 391.0
HKD1_k127_3400073_6 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 362.0
HKD1_k127_3400073_7 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HKD1_k127_3400073_8 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 349.0
HKD1_k127_3400073_9 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 345.0
HKD1_k127_3435390_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 2.419e-319 1008.0
HKD1_k127_3435390_1 - - - - 1.397e-236 752.0
HKD1_k127_3435390_10 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 348.0
HKD1_k127_3435390_11 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 337.0
HKD1_k127_3435390_12 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003068 288.0
HKD1_k127_3435390_13 Protein conserved in bacteria K09939 - - 0.0000000000000000000000000000000001837 147.0
HKD1_k127_3435390_15 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000041 61.0
HKD1_k127_3435390_16 CHRD domain - - - 0.0001926 51.0
HKD1_k127_3435390_17 - - - - 0.0002909 51.0
HKD1_k127_3435390_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 557.0
HKD1_k127_3435390_3 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 513.0
HKD1_k127_3435390_4 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 503.0
HKD1_k127_3435390_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 489.0
HKD1_k127_3435390_6 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 458.0
HKD1_k127_3435390_7 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 451.0
HKD1_k127_3435390_8 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 392.0
HKD1_k127_3435390_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 363.0
HKD1_k127_3447536_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1060.0
HKD1_k127_3447536_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.158e-275 911.0
HKD1_k127_3447536_10 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000004734 227.0
HKD1_k127_3447536_11 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000001388 223.0
HKD1_k127_3447536_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000004811 195.0
HKD1_k127_3447536_13 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000159 186.0
HKD1_k127_3447536_14 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000001788 173.0
HKD1_k127_3447536_15 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.00000000000000000000000000000000000000000317 160.0
HKD1_k127_3447536_16 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000385 146.0
HKD1_k127_3447536_17 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000002709 127.0
HKD1_k127_3447536_18 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000002245 86.0
HKD1_k127_3447536_19 Protein of unknown function (DUF2914) - - - 0.0000000006462 68.0
HKD1_k127_3447536_2 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 481.0
HKD1_k127_3447536_20 Protein of unknown function (DUF1569) - - - 0.00000006345 65.0
HKD1_k127_3447536_21 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000005608 62.0
HKD1_k127_3447536_22 Tetratricopeptide repeat - - - 0.00000272 61.0
HKD1_k127_3447536_23 Serine threonine protein kinase - - - 0.00004801 57.0
HKD1_k127_3447536_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 386.0
HKD1_k127_3447536_4 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 398.0
HKD1_k127_3447536_5 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 366.0
HKD1_k127_3447536_6 Glycerol-3-phosphate dehydrogenase K00057 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 312.0
HKD1_k127_3447536_7 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009653 287.0
HKD1_k127_3447536_8 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000002569 259.0
HKD1_k127_3447536_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000003442 240.0
HKD1_k127_3693372_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 366.0
HKD1_k127_3693372_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004913 147.0
HKD1_k127_3693372_2 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000007238 140.0
HKD1_k127_3693372_3 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.0000000000000000000000000002295 123.0
HKD1_k127_3693372_4 ResB-like family - - - 0.00000000000000000000003775 115.0
HKD1_k127_3693372_5 Domain of unknown function (DUF362) - - - 0.000000002939 70.0
HKD1_k127_3693372_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0001157 50.0
HKD1_k127_3693372_7 - - - - 0.0003476 48.0
HKD1_k127_3727359_0 Sulfatase K19353 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 367.0
HKD1_k127_3727359_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000004805 89.0
HKD1_k127_3795066_0 MmgE PrpD family protein K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 569.0
HKD1_k127_3795066_1 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 411.0
HKD1_k127_3795066_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 351.0
HKD1_k127_3795066_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
HKD1_k127_3795066_4 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
HKD1_k127_3795066_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000002805 194.0
HKD1_k127_3795066_6 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000002704 156.0
HKD1_k127_3795066_7 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000008234 133.0
HKD1_k127_3795066_8 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000007125 121.0
HKD1_k127_3795066_9 Protein of unknown function, DUF393 - - - 0.000006514 53.0
HKD1_k127_3822125_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 568.0
HKD1_k127_3822125_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 559.0
HKD1_k127_3822125_10 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000004646 133.0
HKD1_k127_3822125_11 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.0000000000000000000000003745 110.0
HKD1_k127_3822125_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000005223 105.0
HKD1_k127_3822125_13 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000001937 99.0
HKD1_k127_3822125_14 Glutaredoxin - - - 0.0000000000000006229 92.0
HKD1_k127_3822125_15 AsmA family K07289 - - 0.000000000000909 83.0
HKD1_k127_3822125_2 PFAM Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 417.0
HKD1_k127_3822125_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 409.0
HKD1_k127_3822125_4 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 381.0
HKD1_k127_3822125_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 366.0
HKD1_k127_3822125_6 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 308.0
HKD1_k127_3822125_7 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007617 273.0
HKD1_k127_3822125_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000008098 218.0
HKD1_k127_3822125_9 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000001635 208.0
HKD1_k127_3835448_0 nitric oxide reductase activity K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 586.0
HKD1_k127_3835448_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 503.0
HKD1_k127_3835448_10 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000005424 228.0
HKD1_k127_3835448_11 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000003486 207.0
HKD1_k127_3835448_12 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000003524 188.0
HKD1_k127_3835448_13 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000001839 161.0
HKD1_k127_3835448_14 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.000000000000000000000000000001056 130.0
HKD1_k127_3835448_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000006029 132.0
HKD1_k127_3835448_16 rubredoxin - - - 0.0000000000000000000000008072 104.0
HKD1_k127_3835448_17 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000004992 105.0
HKD1_k127_3835448_18 Rubrerythrin - - - 0.0000000000000596 72.0
HKD1_k127_3835448_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 432.0
HKD1_k127_3835448_20 - - - - 0.000004681 57.0
HKD1_k127_3835448_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 441.0
HKD1_k127_3835448_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 342.0
HKD1_k127_3835448_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 327.0
HKD1_k127_3835448_6 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 324.0
HKD1_k127_3835448_7 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002936 293.0
HKD1_k127_3835448_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006971 291.0
HKD1_k127_3835448_9 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
HKD1_k127_3856838_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 491.0
HKD1_k127_3856838_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 435.0
HKD1_k127_3856838_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000109 104.0
HKD1_k127_3856838_11 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000001206 98.0
HKD1_k127_3856838_12 DUF218 domain - - - 0.00000000000000008687 88.0
HKD1_k127_3856838_13 Acyl transferase domain in polyketide synthase (PKS) enzymes. K11628,K12431,K12432,K12433,K12437,K12440,K12441,K12442,K12443,K15320,K20422,K21254,K21792 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009267,GO:0009273,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0016043,GO:0016053,GO:0018958,GO:0019438,GO:0019725,GO:0019751,GO:0019752,GO:0022607,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032787,GO:0032991,GO:0033554,GO:0034081,GO:0034311,GO:0034312,GO:0042546,GO:0042592,GO:0042594,GO:0042844,GO:0042845,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046173,GO:0046189,GO:0046394,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051704,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:0072330,GO:0097040,GO:0097041,GO:0097089,GO:0098771,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1902321 2.3.1.111,2.3.1.165,2.3.1.237,2.3.1.252 0.000009078 57.0
HKD1_k127_3856838_14 Protein of unknown function (DUF3047) - - - 0.0001269 53.0
HKD1_k127_3856838_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 402.0
HKD1_k127_3856838_3 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 389.0
HKD1_k127_3856838_4 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 314.0
HKD1_k127_3856838_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001808 300.0
HKD1_k127_3856838_6 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 278.0
HKD1_k127_3856838_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002073 261.0
HKD1_k127_3856838_8 molybdopterin binding domain - - - 0.000000000000000000000000000000000000002297 156.0
HKD1_k127_3856838_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000006249 159.0
HKD1_k127_3941690_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.187e-250 783.0
HKD1_k127_3941690_1 Glycosyltransferase like family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 443.0
HKD1_k127_3941690_2 PFAM Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002559 295.0
HKD1_k127_3941690_3 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001123 213.0
HKD1_k127_3941690_5 Tetratricopeptide TPR_2 repeat protein - - - 0.00000212 61.0
HKD1_k127_407819_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 384.0
HKD1_k127_407819_1 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000163 155.0
HKD1_k127_4085044_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 550.0
HKD1_k127_4085044_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 381.0
HKD1_k127_4085044_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000001278 146.0
HKD1_k127_4085044_11 Diguanylate cyclase - - - 0.0000000000000000000000000000000000009379 160.0
HKD1_k127_4085044_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000565 137.0
HKD1_k127_4085044_13 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000001261 112.0
HKD1_k127_4085044_14 Histidine kinase A domain protein - - - 0.000000000000000000000337 105.0
HKD1_k127_4085044_15 Tetratricopeptide repeat - - - 0.000000000398 72.0
HKD1_k127_4085044_16 - - - - 0.000000001272 67.0
HKD1_k127_4085044_17 Tetratricopeptide repeats - - - 0.0000001396 64.0
HKD1_k127_4085044_18 Roadblock/LC7 domain - - - 0.0000004846 59.0
HKD1_k127_4085044_2 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 333.0
HKD1_k127_4085044_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003175 266.0
HKD1_k127_4085044_4 Belongs to the peptidase M24B family K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000004749 252.0
HKD1_k127_4085044_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000007053 258.0
HKD1_k127_4085044_6 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
HKD1_k127_4085044_7 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000002031 203.0
HKD1_k127_4085044_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000008108 164.0
HKD1_k127_4085044_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000003534 167.0
HKD1_k127_4093762_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 9.345e-211 678.0
HKD1_k127_4093762_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.609e-200 676.0
HKD1_k127_4093762_10 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000007389 248.0
HKD1_k127_4093762_11 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000004724 240.0
HKD1_k127_4093762_12 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000005702 230.0
HKD1_k127_4093762_13 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000746 222.0
HKD1_k127_4093762_14 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000002704 203.0
HKD1_k127_4093762_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000001876 180.0
HKD1_k127_4093762_16 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000003753 159.0
HKD1_k127_4093762_17 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000005434 162.0
HKD1_k127_4093762_18 PFAM thioesterase superfamily K02614 - - 0.00000000002504 78.0
HKD1_k127_4093762_19 Glutaredoxin K03676 - - 0.00000001004 57.0
HKD1_k127_4093762_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 471.0
HKD1_k127_4093762_20 Rubrerythrin - - - 0.0000191 54.0
HKD1_k127_4093762_21 Thioredoxin-like - - - 0.00003796 55.0
HKD1_k127_4093762_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 463.0
HKD1_k127_4093762_4 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 434.0
HKD1_k127_4093762_5 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 396.0
HKD1_k127_4093762_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 357.0
HKD1_k127_4093762_7 Collagenase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 356.0
HKD1_k127_4093762_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 331.0
HKD1_k127_4093762_9 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 306.0
HKD1_k127_4177296_0 Glycogen debranching enzyme - - - 0.0 1390.0
HKD1_k127_4177296_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 484.0
HKD1_k127_4177296_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002994 301.0
HKD1_k127_4177296_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000141 212.0
HKD1_k127_4177296_4 - - - - 0.0000000000000000000000000000000000000000007055 160.0
HKD1_k127_4200579_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 492.0
HKD1_k127_4200579_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 447.0
HKD1_k127_4200579_10 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000001809 109.0
HKD1_k127_4200579_11 binding domain protein - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.00000000000000005034 84.0
HKD1_k127_4200579_12 Cytochrome c554 and c-prime - - - 0.0000000001929 71.0
HKD1_k127_4200579_13 Rubrerythrin - - - 0.00005876 49.0
HKD1_k127_4200579_14 Rubrerythrin - - - 0.0002332 50.0
HKD1_k127_4200579_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 403.0
HKD1_k127_4200579_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005361 277.0
HKD1_k127_4200579_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000008532 199.0
HKD1_k127_4200579_5 IMP dehydrogenase activity K04767 - - 0.000000000000000000000000000000000000000000000004044 180.0
HKD1_k127_4200579_6 Transporter associated domain K03699 - - 0.000000000000000000000000000000000164 148.0
HKD1_k127_4200579_7 Nitroreductase family - - - 0.00000000000000000000000000000000691 138.0
HKD1_k127_4200579_8 Thioredoxin-like K02199 - - 0.000000000000000000000000002972 118.0
HKD1_k127_4200579_9 LysM domain - - - 0.000000000000000000000000004959 130.0
HKD1_k127_4216274_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1129.0
HKD1_k127_4216274_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.652e-285 890.0
HKD1_k127_4216274_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 535.0
HKD1_k127_4216274_11 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 555.0
HKD1_k127_4216274_12 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 524.0
HKD1_k127_4216274_13 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 497.0
HKD1_k127_4216274_14 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 469.0
HKD1_k127_4216274_15 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 452.0
HKD1_k127_4216274_16 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 422.0
HKD1_k127_4216274_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 419.0
HKD1_k127_4216274_18 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 426.0
HKD1_k127_4216274_19 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 387.0
HKD1_k127_4216274_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.482e-240 755.0
HKD1_k127_4216274_20 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 367.0
HKD1_k127_4216274_21 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 362.0
HKD1_k127_4216274_22 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
HKD1_k127_4216274_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
HKD1_k127_4216274_24 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 333.0
HKD1_k127_4216274_25 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 326.0
HKD1_k127_4216274_26 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 338.0
HKD1_k127_4216274_27 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 309.0
HKD1_k127_4216274_28 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 305.0
HKD1_k127_4216274_29 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 303.0
HKD1_k127_4216274_3 Elongation factor Tu domain 2 K02355 - - 5.844e-240 761.0
HKD1_k127_4216274_30 Na phosphate symporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005254 296.0
HKD1_k127_4216274_31 ThiF family K03148,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 284.0
HKD1_k127_4216274_32 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
HKD1_k127_4216274_33 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000595 268.0
HKD1_k127_4216274_34 DRTGG domain K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000288 257.0
HKD1_k127_4216274_35 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000001108 250.0
HKD1_k127_4216274_36 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000001599 235.0
HKD1_k127_4216274_37 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000003966 218.0
HKD1_k127_4216274_38 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000001901 208.0
HKD1_k127_4216274_39 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001965 224.0
HKD1_k127_4216274_4 Acyl-CoA synthetase (NDP forming) K09181 - - 2.525e-200 645.0
HKD1_k127_4216274_40 Transcriptional regulator, CarD family K07736 - - 0.00000000000000000000000000000000000000000000000000006869 191.0
HKD1_k127_4216274_41 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000002324 195.0
HKD1_k127_4216274_42 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000007629 179.0
HKD1_k127_4216274_43 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000009048 180.0
HKD1_k127_4216274_44 molybdenum cofactor - - - 0.000000000000000000000000000000000000000001319 167.0
HKD1_k127_4216274_45 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000002649 107.0
HKD1_k127_4216274_46 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000005132 113.0
HKD1_k127_4216274_47 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000001376 107.0
HKD1_k127_4216274_48 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000002626 92.0
HKD1_k127_4216274_49 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000007153 104.0
HKD1_k127_4216274_5 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 3.78e-196 627.0
HKD1_k127_4216274_50 - - - - 0.0000000000000000005258 103.0
HKD1_k127_4216274_51 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000001061 96.0
HKD1_k127_4216274_52 Helix-turn-helix domain - - - 0.00000000000000001069 93.0
HKD1_k127_4216274_53 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000291 77.0
HKD1_k127_4216274_54 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000005126 52.0
HKD1_k127_4216274_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 621.0
HKD1_k127_4216274_7 Domain of unknown function (DUF3552) K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 607.0
HKD1_k127_4216274_8 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 634.0
HKD1_k127_4216274_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 558.0
HKD1_k127_4222396_0 Heat shock 70 kDa protein K04043 - - 1.657e-282 880.0
HKD1_k127_4222396_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 477.0
HKD1_k127_4222396_10 Domain of unknown function (DUF1844) - - - 0.000000000182 67.0
HKD1_k127_4222396_11 Response regulator receiver domain K02658 - - 0.00001389 54.0
HKD1_k127_4222396_2 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 486.0
HKD1_k127_4222396_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 415.0
HKD1_k127_4222396_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 376.0
HKD1_k127_4222396_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 249.0
HKD1_k127_4222396_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000006571 188.0
HKD1_k127_4222396_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000008858 181.0
HKD1_k127_4222396_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000813 161.0
HKD1_k127_4222396_9 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000001654 153.0
HKD1_k127_4292535_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1978.0
HKD1_k127_4292535_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1745.0
HKD1_k127_4292535_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000008745 138.0
HKD1_k127_4292535_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002344 87.0
HKD1_k127_4292535_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000006459 68.0
HKD1_k127_4292535_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000006902 70.0
HKD1_k127_4292535_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1077.0
HKD1_k127_4292535_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 321.0
HKD1_k127_4292535_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001293 243.0
HKD1_k127_4292535_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000003165 222.0
HKD1_k127_4292535_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001057 217.0
HKD1_k127_4292535_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002895 212.0
HKD1_k127_4292535_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000001815 156.0
HKD1_k127_4292535_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000001231 145.0
HKD1_k127_4327279_0 Endopeptidase La K04076 - 3.4.21.53 3.555e-231 741.0
HKD1_k127_4327279_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 425.0
HKD1_k127_4327279_10 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000002022 112.0
HKD1_k127_4327279_11 Cache_2 - - - 0.00000000000000000000000006747 108.0
HKD1_k127_4327279_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 421.0
HKD1_k127_4327279_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
HKD1_k127_4327279_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 371.0
HKD1_k127_4327279_5 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 358.0
HKD1_k127_4327279_6 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 347.0
HKD1_k127_4327279_7 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 314.0
HKD1_k127_4327279_8 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 310.0
HKD1_k127_4327279_9 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000199 159.0
HKD1_k127_4494610_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1095.0
HKD1_k127_4494610_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 597.0
HKD1_k127_4494610_10 Metal-dependent phosphohydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 316.0
HKD1_k127_4494610_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 312.0
HKD1_k127_4494610_12 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
HKD1_k127_4494610_13 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005725 273.0
HKD1_k127_4494610_14 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001493 265.0
HKD1_k127_4494610_15 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000006124 234.0
HKD1_k127_4494610_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000002411 211.0
HKD1_k127_4494610_17 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000005751 224.0
HKD1_k127_4494610_18 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000000274 201.0
HKD1_k127_4494610_19 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000001002 207.0
HKD1_k127_4494610_2 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 571.0
HKD1_k127_4494610_20 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000002292 145.0
HKD1_k127_4494610_21 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000003419 123.0
HKD1_k127_4494610_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000001814 105.0
HKD1_k127_4494610_23 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000003411 110.0
HKD1_k127_4494610_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000005236 103.0
HKD1_k127_4494610_25 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000002258 93.0
HKD1_k127_4494610_26 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000008112 78.0
HKD1_k127_4494610_27 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000001192 74.0
HKD1_k127_4494610_28 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000001135 74.0
HKD1_k127_4494610_29 Lipopolysaccharide-assembly - - - 0.0000002567 63.0
HKD1_k127_4494610_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
HKD1_k127_4494610_30 Domain of unknown function (DUF4388) - - - 0.000005302 58.0
HKD1_k127_4494610_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 396.0
HKD1_k127_4494610_5 AAA domain K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 397.0
HKD1_k127_4494610_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 364.0
HKD1_k127_4494610_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 357.0
HKD1_k127_4494610_8 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 327.0
HKD1_k127_4494610_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 340.0
HKD1_k127_4521313_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 595.0
HKD1_k127_4521313_1 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 555.0
HKD1_k127_4521313_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 446.0
HKD1_k127_4521313_3 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006643 284.0
HKD1_k127_4521313_4 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008877 254.0
HKD1_k127_4521313_5 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000286 203.0
HKD1_k127_4521313_6 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000000000000000000000000000001144 188.0
HKD1_k127_4521313_7 Transposase - - - 0.0000000000007625 72.0
HKD1_k127_4521313_8 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0000000007151 59.0
HKD1_k127_4552764_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1386.0
HKD1_k127_4552764_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 2.197e-243 763.0
HKD1_k127_4552764_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 359.0
HKD1_k127_4552764_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 348.0
HKD1_k127_4552764_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 301.0
HKD1_k127_4552764_13 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002399 265.0
HKD1_k127_4552764_14 sigma factor activity K02405,K03093 - - 0.0000000000000000000000000000000000000000000000000000000000001603 222.0
HKD1_k127_4552764_15 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000284 237.0
HKD1_k127_4552764_16 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HKD1_k127_4552764_17 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000006301 235.0
HKD1_k127_4552764_18 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000002026 198.0
HKD1_k127_4552764_19 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000003887 196.0
HKD1_k127_4552764_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 9.742e-212 677.0
HKD1_k127_4552764_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000009251 188.0
HKD1_k127_4552764_21 Thioesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000000000000000006949 180.0
HKD1_k127_4552764_22 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000001154 195.0
HKD1_k127_4552764_23 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000004282 160.0
HKD1_k127_4552764_24 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.000000000000000000000000000000000000003806 168.0
HKD1_k127_4552764_25 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000004826 167.0
HKD1_k127_4552764_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005618 159.0
HKD1_k127_4552764_27 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000007699 155.0
HKD1_k127_4552764_28 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000001248 147.0
HKD1_k127_4552764_29 RmuC family K09760 - - 0.00000000000000000000000000000000002911 149.0
HKD1_k127_4552764_3 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 584.0
HKD1_k127_4552764_30 Cytochrome c554 and c-prime - - - 0.000000000000000000000000001108 129.0
HKD1_k127_4552764_31 TPM domain K06872 - - 0.00000000000000000000000002263 124.0
HKD1_k127_4552764_32 Zincin-like metallopeptidase - - - 0.00000000000000000000000003837 124.0
HKD1_k127_4552764_33 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000009449 115.0
HKD1_k127_4552764_34 nucleotidyltransferase activity - - - 0.0000000000000000006447 96.0
HKD1_k127_4552764_35 oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000006812 72.0
HKD1_k127_4552764_36 signal sequence binding K07152 - - 0.00000000001761 66.0
HKD1_k127_4552764_37 YacP-like NYN domain K06962 - - 0.00000000002393 72.0
HKD1_k127_4552764_38 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000003183 72.0
HKD1_k127_4552764_4 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 534.0
HKD1_k127_4552764_5 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 505.0
HKD1_k127_4552764_6 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 455.0
HKD1_k127_4552764_7 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 445.0
HKD1_k127_4552764_8 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 417.0
HKD1_k127_4552764_9 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 363.0
HKD1_k127_4687771_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1680.0
HKD1_k127_4687771_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 449.0
HKD1_k127_4687771_10 - - - - 0.00000000009285 64.0
HKD1_k127_4687771_11 - - - - 0.000000002353 65.0
HKD1_k127_4687771_12 Aminoacyl-tRNA editing domain - - - 0.00000002427 64.0
HKD1_k127_4687771_2 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 340.0
HKD1_k127_4687771_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007979 286.0
HKD1_k127_4687771_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000452 248.0
HKD1_k127_4687771_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
HKD1_k127_4687771_6 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000001644 154.0
HKD1_k127_4687771_7 Universal stress protein - - - 0.0000000000000000000000000000000000004438 146.0
HKD1_k127_4687771_8 dUTPase - - - 0.0000000000000000000000000000000000009151 141.0
HKD1_k127_4687771_9 Tetratricopeptide repeats - - - 0.00000000000002368 83.0
HKD1_k127_4761514_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1332.0
HKD1_k127_4761514_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 536.0
HKD1_k127_4761514_2 Alkaline phosphatase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 331.0
HKD1_k127_4761514_3 - - - - 0.000000000000000000000000000000000000000000000000000000002649 211.0
HKD1_k127_4761514_4 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000000000905 164.0
HKD1_k127_4761514_5 - - - - 0.0000000000000000000000000000000000000001263 161.0
HKD1_k127_4761514_7 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000006202 110.0
HKD1_k127_4761514_8 YtxH-like protein - - - 0.000004527 53.0
HKD1_k127_4829851_0 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 509.0
HKD1_k127_4829851_1 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002207 260.0
HKD1_k127_4829851_2 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
HKD1_k127_4829851_3 - - - - 0.000006607 56.0
HKD1_k127_4832410_0 ATPase BadF BadG BcrA BcrD type - - - 2.278e-315 996.0
HKD1_k127_4832410_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.253e-295 929.0
HKD1_k127_4832410_10 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 351.0
HKD1_k127_4832410_11 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 348.0
HKD1_k127_4832410_12 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 314.0
HKD1_k127_4832410_13 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 312.0
HKD1_k127_4832410_14 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 294.0
HKD1_k127_4832410_15 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009896 295.0
HKD1_k127_4832410_16 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003736 279.0
HKD1_k127_4832410_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000004287 212.0
HKD1_k127_4832410_18 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000003781 185.0
HKD1_k127_4832410_19 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000004776 185.0
HKD1_k127_4832410_2 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 588.0
HKD1_k127_4832410_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000003004 160.0
HKD1_k127_4832410_21 SAM-dependent methyltransferase - - - 0.0000000000000000000000000000000006127 151.0
HKD1_k127_4832410_22 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000001051 123.0
HKD1_k127_4832410_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000001211 81.0
HKD1_k127_4832410_24 Protein of unknown function (DUF3426) - - - 0.0000000000000007433 91.0
HKD1_k127_4832410_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000003508 74.0
HKD1_k127_4832410_26 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000007193 78.0
HKD1_k127_4832410_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000001145 72.0
HKD1_k127_4832410_28 Modulates RecA activity K03565 - - 0.000001018 58.0
HKD1_k127_4832410_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 578.0
HKD1_k127_4832410_30 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0008193 51.0
HKD1_k127_4832410_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 525.0
HKD1_k127_4832410_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
HKD1_k127_4832410_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 475.0
HKD1_k127_4832410_7 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 410.0
HKD1_k127_4832410_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 390.0
HKD1_k127_4832410_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 363.0
HKD1_k127_4833200_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 565.0
HKD1_k127_4833200_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000002146 239.0
HKD1_k127_4833200_2 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000002905 154.0
HKD1_k127_490808_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1202.0
HKD1_k127_490808_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 500.0
HKD1_k127_490808_10 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000002005 164.0
HKD1_k127_490808_11 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000003263 138.0
HKD1_k127_490808_12 WD40 repeat-like protein - - - 0.0000000000000000000000000000005482 139.0
HKD1_k127_490808_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 461.0
HKD1_k127_490808_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 332.0
HKD1_k127_490808_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 327.0
HKD1_k127_490808_5 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002512 242.0
HKD1_k127_490808_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000002088 212.0
HKD1_k127_490808_7 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000003645 171.0
HKD1_k127_490808_8 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000002291 166.0
HKD1_k127_490808_9 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000001261 151.0
HKD1_k127_491010_0 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 590.0
HKD1_k127_491010_1 pilus organization K07346 - - 0.000000000000000000000000000000000000000000000000000000000000003456 226.0
HKD1_k127_491010_2 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000001431 215.0
HKD1_k127_491010_3 Spore Coat Protein U domain - - - 0.0000000000000000000000006791 113.0
HKD1_k127_491010_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000207 90.0
HKD1_k127_491010_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000003052 73.0
HKD1_k127_491010_6 Spore Coat Protein U domain - - - 0.00000001523 64.0
HKD1_k127_491010_7 Spore Coat Protein U domain - - - 0.00000003508 60.0
HKD1_k127_49442_0 MotA TolQ ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000009576 153.0
HKD1_k127_49442_1 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000004988 96.0
HKD1_k127_49442_2 amine dehydrogenase activity K13730 - - 0.000000000000000001021 100.0
HKD1_k127_49442_5 formate dehydrogenase - - - 0.00006016 52.0
HKD1_k127_49442_6 denitrification pathway - - - 0.000241 51.0
HKD1_k127_4994766_0 belongs to the aldehyde dehydrogenase family K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 547.0
HKD1_k127_4994766_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 522.0
HKD1_k127_4994766_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000001453 255.0
HKD1_k127_4994766_11 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000005482 273.0
HKD1_k127_4994766_12 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000000003978 230.0
HKD1_k127_4994766_13 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000003429 214.0
HKD1_k127_4994766_14 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000004924 181.0
HKD1_k127_4994766_15 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000001202 195.0
HKD1_k127_4994766_16 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000004555 158.0
HKD1_k127_4994766_17 acetyltransferase K18815 - 2.3.1.82 0.00000000000000000000000000000000001326 145.0
HKD1_k127_4994766_18 Helix-turn-helix domain - - - 0.00000000000000000000000000000000001466 141.0
HKD1_k127_4994766_19 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000002476 117.0
HKD1_k127_4994766_2 Radical SAM K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 458.0
HKD1_k127_4994766_20 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000001375 113.0
HKD1_k127_4994766_21 - - - - 0.000000000000000003894 93.0
HKD1_k127_4994766_22 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000004889 73.0
HKD1_k127_4994766_23 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000003628 68.0
HKD1_k127_4994766_24 Protein of unknown function (DUF2889) - - - 0.00002699 54.0
HKD1_k127_4994766_3 Belongs to the N(4) N(6)-methyltransferase family K07319 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
HKD1_k127_4994766_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 386.0
HKD1_k127_4994766_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 382.0
HKD1_k127_4994766_6 peptidase M29 K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 338.0
HKD1_k127_4994766_7 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 327.0
HKD1_k127_4994766_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 325.0
HKD1_k127_4994766_9 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 287.0
HKD1_k127_5028775_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 333.0
HKD1_k127_5028775_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001214 292.0
HKD1_k127_5028775_10 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000008839 99.0
HKD1_k127_5028775_11 PFAM helix-turn-helix domain protein - - - 0.000000000000000001863 88.0
HKD1_k127_5028775_12 -O-antigen K02847,K13009 - - 0.00000000001718 76.0
HKD1_k127_5028775_13 Pilus assembly protein, PilP K02665 - - 0.000000000115 73.0
HKD1_k127_5028775_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002368 267.0
HKD1_k127_5028775_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000003744 271.0
HKD1_k127_5028775_4 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
HKD1_k127_5028775_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000004551 238.0
HKD1_k127_5028775_6 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000001453 247.0
HKD1_k127_5028775_7 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000001466 195.0
HKD1_k127_5028775_8 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000002799 145.0
HKD1_k127_5028775_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000002452 152.0
HKD1_k127_5054820_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.166e-250 795.0
HKD1_k127_5054820_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.054e-205 645.0
HKD1_k127_5054820_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 433.0
HKD1_k127_5054820_11 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 426.0
HKD1_k127_5054820_12 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 408.0
HKD1_k127_5054820_13 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 404.0
HKD1_k127_5054820_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 392.0
HKD1_k127_5054820_15 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 369.0
HKD1_k127_5054820_16 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 363.0
HKD1_k127_5054820_17 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 346.0
HKD1_k127_5054820_18 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 363.0
HKD1_k127_5054820_19 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 328.0
HKD1_k127_5054820_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 619.0
HKD1_k127_5054820_20 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 325.0
HKD1_k127_5054820_21 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 327.0
HKD1_k127_5054820_22 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 329.0
HKD1_k127_5054820_23 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 323.0
HKD1_k127_5054820_24 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001742 283.0
HKD1_k127_5054820_25 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001765 282.0
HKD1_k127_5054820_26 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004658 280.0
HKD1_k127_5054820_27 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000941 280.0
HKD1_k127_5054820_28 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001656 261.0
HKD1_k127_5054820_29 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000009464 266.0
HKD1_k127_5054820_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 590.0
HKD1_k127_5054820_30 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000005813 249.0
HKD1_k127_5054820_31 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000001483 244.0
HKD1_k127_5054820_32 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000001899 241.0
HKD1_k127_5054820_33 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000199 243.0
HKD1_k127_5054820_34 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000002647 233.0
HKD1_k127_5054820_35 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000001069 229.0
HKD1_k127_5054820_36 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000003332 228.0
HKD1_k127_5054820_37 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000003272 195.0
HKD1_k127_5054820_38 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000001477 188.0
HKD1_k127_5054820_39 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000374 191.0
HKD1_k127_5054820_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 578.0
HKD1_k127_5054820_40 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000002187 182.0
HKD1_k127_5054820_41 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000851 175.0
HKD1_k127_5054820_42 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000001068 186.0
HKD1_k127_5054820_43 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000006967 155.0
HKD1_k127_5054820_44 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000897 151.0
HKD1_k127_5054820_45 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000004726 147.0
HKD1_k127_5054820_46 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000002111 158.0
HKD1_k127_5054820_47 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000006837 146.0
HKD1_k127_5054820_48 Reverse transcriptase-like K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000000000001174 142.0
HKD1_k127_5054820_49 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 0.00000000000000000000000000000002133 142.0
HKD1_k127_5054820_5 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 576.0
HKD1_k127_5054820_50 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000005102 143.0
HKD1_k127_5054820_51 Psort location Cytoplasmic, score 8.87 K03925 - - 0.00000000000000000000000000000006598 129.0
HKD1_k127_5054820_52 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000001203 132.0
HKD1_k127_5054820_53 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000326 131.0
HKD1_k127_5054820_54 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000001904 119.0
HKD1_k127_5054820_55 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000001665 122.0
HKD1_k127_5054820_56 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000008317 104.0
HKD1_k127_5054820_57 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000008736 104.0
HKD1_k127_5054820_58 - - - - 0.000000000000000000000007736 103.0
HKD1_k127_5054820_59 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000001115 103.0
HKD1_k127_5054820_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
HKD1_k127_5054820_60 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000002765 93.0
HKD1_k127_5054820_61 phosphocarrier protein HPr K11189 - - 0.0000000000000000004524 99.0
HKD1_k127_5054820_62 Diguanylate cyclase - - - 0.000000000000000002893 96.0
HKD1_k127_5054820_64 cell division protein FtsL - - - 0.0001678 53.0
HKD1_k127_5054820_7 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 500.0
HKD1_k127_5054820_8 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 514.0
HKD1_k127_5054820_9 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 487.0
HKD1_k127_5056748_0 Berberine and berberine like - - - 2.408e-206 653.0
HKD1_k127_5056748_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 616.0
HKD1_k127_5056748_2 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 573.0
HKD1_k127_5056748_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 395.0
HKD1_k127_5056748_4 thiolester hydrolase activity - - - 0.0000000000000000000001506 112.0
HKD1_k127_5056748_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000008994 82.0
HKD1_k127_5056748_6 - - - - 0.00003146 52.0
HKD1_k127_5059505_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1189.0
HKD1_k127_5059505_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.406e-245 780.0
HKD1_k127_5059505_10 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0001251 51.0
HKD1_k127_5059505_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 535.0
HKD1_k127_5059505_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 399.0
HKD1_k127_5059505_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 381.0
HKD1_k127_5059505_5 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 347.0
HKD1_k127_5059505_6 PFAM OmpA MotB domain protein K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001847 251.0
HKD1_k127_5059505_7 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000003108 232.0
HKD1_k127_5059505_8 - - - - 0.0000000000000000000005639 98.0
HKD1_k127_5059505_9 - - - - 0.000000000000000000004305 94.0
HKD1_k127_5076136_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 501.0
HKD1_k127_5076136_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 310.0
HKD1_k127_5076136_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000004115 248.0
HKD1_k127_5076136_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000006528 207.0
HKD1_k127_5076136_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000001411 191.0
HKD1_k127_5076136_5 Crp Fnr family K21563 - - 0.0000000000000000000000000000000000000000000000002222 184.0
HKD1_k127_5076136_6 ACT domain K03567 - - 0.0000000000000000000000000000000000000000000000005455 182.0
HKD1_k127_5076136_7 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000002024 146.0
HKD1_k127_5076136_8 Diguanylate cyclase - - - 0.0000000000000000000002935 106.0
HKD1_k127_5076136_9 Cytochrome C' - - - 0.0005437 49.0
HKD1_k127_5184611_0 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 377.0
HKD1_k127_5184611_1 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000000000000000000000000000000000000000000001588 170.0
HKD1_k127_5184611_2 - - - - 0.00000000000000000000000000003366 127.0
HKD1_k127_5198744_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.389e-198 642.0
HKD1_k127_5198744_1 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 585.0
HKD1_k127_5198744_10 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000886 209.0
HKD1_k127_5198744_11 Domain of unknown function (DUF1848) - - - 0.000000000000000000000000000000000000000000005978 173.0
HKD1_k127_5198744_12 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000305 111.0
HKD1_k127_5198744_13 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000006963 103.0
HKD1_k127_5198744_14 Late embryogenesis abundant protein - - - 0.000001104 61.0
HKD1_k127_5198744_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 478.0
HKD1_k127_5198744_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 473.0
HKD1_k127_5198744_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 414.0
HKD1_k127_5198744_5 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 408.0
HKD1_k127_5198744_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 338.0
HKD1_k127_5198744_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 300.0
HKD1_k127_5198744_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD1_k127_5198744_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001248 254.0
HKD1_k127_5224367_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1135.0
HKD1_k127_5224367_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.186e-242 760.0
HKD1_k127_5224367_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 302.0
HKD1_k127_5224367_11 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 315.0
HKD1_k127_5224367_12 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007019 280.0
HKD1_k127_5224367_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005776 284.0
HKD1_k127_5224367_14 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000483 222.0
HKD1_k127_5224367_15 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HKD1_k127_5224367_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000005767 211.0
HKD1_k127_5224367_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000001445 158.0
HKD1_k127_5224367_18 Peptidase family M23 - - - 0.000000000000000000000000000000000000000003435 167.0
HKD1_k127_5224367_19 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000005284 149.0
HKD1_k127_5224367_2 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 7.396e-236 745.0
HKD1_k127_5224367_20 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000006933 147.0
HKD1_k127_5224367_21 dihydromethanopterin reductase activity - - - 0.000000000000000001179 89.0
HKD1_k127_5224367_22 - - - - 0.000000000612 63.0
HKD1_k127_5224367_23 Protein of unknown function (DUF465) K09794 - - 0.0000001912 55.0
HKD1_k127_5224367_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 539.0
HKD1_k127_5224367_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 515.0
HKD1_k127_5224367_5 General secretory system II protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 506.0
HKD1_k127_5224367_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 373.0
HKD1_k127_5224367_7 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 335.0
HKD1_k127_5224367_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 333.0
HKD1_k127_5224367_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 325.0
HKD1_k127_5229373_0 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 451.0
HKD1_k127_5229373_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 447.0
HKD1_k127_5229373_2 RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.00000000000000000000000000000000000000000000000005092 184.0
HKD1_k127_5229373_3 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.00000000000000000000000000000000000000009107 156.0
HKD1_k127_5229373_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000003183 56.0
HKD1_k127_5229373_5 Domain of unknown function (DUF4395) - - - 0.00000158 58.0
HKD1_k127_5229373_6 Putative zinc-finger - - - 0.000001906 61.0
HKD1_k127_5243539_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 546.0
HKD1_k127_5243539_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 479.0
HKD1_k127_5243539_2 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 402.0
HKD1_k127_5243539_3 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 333.0
HKD1_k127_5243539_4 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000003515 169.0
HKD1_k127_5243539_5 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000005223 153.0
HKD1_k127_5243539_6 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000000007437 124.0
HKD1_k127_5243539_7 Glycine cleavage H-protein - - - 0.000000000000000000000001261 112.0
HKD1_k127_5243539_8 Domain of unknown function (DUF4382) - - - 0.0001568 48.0
HKD1_k127_5260511_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 365.0
HKD1_k127_5260511_1 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001888 267.0
HKD1_k127_5260511_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000004956 245.0
HKD1_k127_5260511_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000001446 154.0
HKD1_k127_5260511_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000006312 131.0
HKD1_k127_5260511_5 radical SAM domain protein - - - 0.000000000000000000008426 104.0
HKD1_k127_5260511_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000001249 92.0
HKD1_k127_5307658_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1024.0
HKD1_k127_5307658_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.574e-298 943.0
HKD1_k127_5307658_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000003016 187.0
HKD1_k127_5307658_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000866 163.0
HKD1_k127_5307658_12 Protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000000726 138.0
HKD1_k127_5307658_14 Vitamin K epoxide reductase family - - - 0.000000155 57.0
HKD1_k127_5307658_2 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 3.754e-243 775.0
HKD1_k127_5307658_3 PFAM FAD linked oxidase domain protein K00004,K00102,K00104 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15 6.262e-242 755.0
HKD1_k127_5307658_4 Berberine and berberine like - - - 5.759e-220 694.0
HKD1_k127_5307658_5 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 628.0
HKD1_k127_5307658_6 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 606.0
HKD1_k127_5307658_7 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 600.0
HKD1_k127_5307658_8 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 483.0
HKD1_k127_5307658_9 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 455.0
HKD1_k127_5395174_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K18138 - - 0.0 1665.0
HKD1_k127_5395174_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1349.0
HKD1_k127_5395174_10 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 399.0
HKD1_k127_5395174_11 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 389.0
HKD1_k127_5395174_12 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 333.0
HKD1_k127_5395174_13 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
HKD1_k127_5395174_14 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HKD1_k127_5395174_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000003631 247.0
HKD1_k127_5395174_16 electron transfer activity K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000009689 240.0
HKD1_k127_5395174_17 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000001275 221.0
HKD1_k127_5395174_18 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000002904 184.0
HKD1_k127_5395174_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000001292 160.0
HKD1_k127_5395174_2 cytochrome c - - - 2.572e-253 799.0
HKD1_k127_5395174_20 YceI-like domain - - - 0.00000000000000000000000000000000009886 141.0
HKD1_k127_5395174_21 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000005213 138.0
HKD1_k127_5395174_22 - - - - 0.0000000000000000000000528 102.0
HKD1_k127_5395174_23 Rieske [2Fe-2S] domain - - - 0.000000000000000006675 91.0
HKD1_k127_5395174_24 - - - - 0.0000000003169 72.0
HKD1_k127_5395174_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.144e-224 709.0
HKD1_k127_5395174_4 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 547.0
HKD1_k127_5395174_5 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 484.0
HKD1_k127_5395174_6 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 485.0
HKD1_k127_5395174_7 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 459.0
HKD1_k127_5395174_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 427.0
HKD1_k127_5395174_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 420.0
HKD1_k127_5469593_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 609.0
HKD1_k127_5469593_1 Natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 594.0
HKD1_k127_5469593_10 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 379.0
HKD1_k127_5469593_11 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 366.0
HKD1_k127_5469593_12 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 353.0
HKD1_k127_5469593_13 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 347.0
HKD1_k127_5469593_14 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 301.0
HKD1_k127_5469593_15 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
HKD1_k127_5469593_16 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000004156 250.0
HKD1_k127_5469593_17 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000001056 214.0
HKD1_k127_5469593_18 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000816 140.0
HKD1_k127_5469593_19 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000002798 131.0
HKD1_k127_5469593_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 579.0
HKD1_k127_5469593_20 MacB-like periplasmic core domain K02004 - - 0.0000000000000000002404 93.0
HKD1_k127_5469593_21 Uncharacterized small protein (DUF2292) - - - 0.00000001646 58.0
HKD1_k127_5469593_22 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0002688 48.0
HKD1_k127_5469593_23 DsrE/DsrF-like family - - - 0.0007889 49.0
HKD1_k127_5469593_3 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
HKD1_k127_5469593_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 514.0
HKD1_k127_5469593_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 492.0
HKD1_k127_5469593_6 Sigma-54 interaction domain K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 443.0
HKD1_k127_5469593_7 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 435.0
HKD1_k127_5469593_8 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 421.0
HKD1_k127_5469593_9 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 413.0
HKD1_k127_5523216_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 603.0
HKD1_k127_5523216_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 531.0
HKD1_k127_5523216_10 Thioredoxin-like domain - - - 0.00000000000004531 80.0
HKD1_k127_5523216_11 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0006648 44.0
HKD1_k127_5523216_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 504.0
HKD1_k127_5523216_3 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 445.0
HKD1_k127_5523216_4 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 413.0
HKD1_k127_5523216_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 401.0
HKD1_k127_5523216_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 385.0
HKD1_k127_5523216_7 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000001112 139.0
HKD1_k127_5523216_8 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000001121 124.0
HKD1_k127_5523216_9 Glycine reductase complex selenoprotein A - - - 0.0000000000000000000008817 98.0
HKD1_k127_556190_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1494.0
HKD1_k127_556190_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.717e-272 847.0
HKD1_k127_556190_10 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 458.0
HKD1_k127_556190_11 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 494.0
HKD1_k127_556190_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 444.0
HKD1_k127_556190_13 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 457.0
HKD1_k127_556190_14 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 442.0
HKD1_k127_556190_15 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 414.0
HKD1_k127_556190_16 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 414.0
HKD1_k127_556190_17 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 399.0
HKD1_k127_556190_18 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 374.0
HKD1_k127_556190_19 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
HKD1_k127_556190_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 9.091e-202 644.0
HKD1_k127_556190_20 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 352.0
HKD1_k127_556190_21 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 351.0
HKD1_k127_556190_22 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 332.0
HKD1_k127_556190_23 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
HKD1_k127_556190_24 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 320.0
HKD1_k127_556190_25 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
HKD1_k127_556190_26 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
HKD1_k127_556190_27 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000002945 231.0
HKD1_k127_556190_28 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000002369 245.0
HKD1_k127_556190_29 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000004082 241.0
HKD1_k127_556190_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 657.0
HKD1_k127_556190_30 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000008029 219.0
HKD1_k127_556190_31 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000006874 229.0
HKD1_k127_556190_32 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000001639 221.0
HKD1_k127_556190_33 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000008128 214.0
HKD1_k127_556190_34 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000004728 198.0
HKD1_k127_556190_35 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000002173 169.0
HKD1_k127_556190_36 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000004171 164.0
HKD1_k127_556190_37 Diguanylate cyclase - - - 0.00000000000000000000000000000000000001343 166.0
HKD1_k127_556190_38 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000000000000001862 142.0
HKD1_k127_556190_39 2-hydroxyglutaryl-CoA dehydratase, D-component K04112,K20026 - 1.3.7.8,4.2.1.157 0.000000000000000000000000000004472 134.0
HKD1_k127_556190_4 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 587.0
HKD1_k127_556190_40 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000002423 118.0
HKD1_k127_556190_41 Cold shock protein K03704 - - 0.000000000000000000000003027 103.0
HKD1_k127_556190_43 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000002544 96.0
HKD1_k127_556190_44 Tetratricopeptide repeat - - - 0.000000000000000001541 100.0
HKD1_k127_556190_45 NHL repeat - - - 0.000000184 56.0
HKD1_k127_556190_46 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000002841 56.0
HKD1_k127_556190_47 Cell division protein K03591 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0031224,GO:0031226,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0003989 50.0
HKD1_k127_556190_5 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 568.0
HKD1_k127_556190_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 535.0
HKD1_k127_556190_7 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 500.0
HKD1_k127_556190_8 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 488.0
HKD1_k127_556190_9 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 468.0
HKD1_k127_5606897_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 5.293e-261 826.0
HKD1_k127_5606897_1 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 344.0
HKD1_k127_5606897_2 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000001461 250.0
HKD1_k127_5606897_3 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000005865 188.0
HKD1_k127_5606897_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000122 160.0
HKD1_k127_5606897_5 STAS domain - - - 0.000000000002008 76.0
HKD1_k127_5612155_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 468.0
HKD1_k127_5612155_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 439.0
HKD1_k127_5612155_10 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000001896 184.0
HKD1_k127_5612155_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001519 166.0
HKD1_k127_5612155_12 MaoC like domain - - - 0.00000000000000000000000000000000000000009208 157.0
HKD1_k127_5612155_13 Essential cell division protein K03589 - - 0.00000000000000000000000000000001173 137.0
HKD1_k127_5612155_14 YGGT family K02221 - - 0.000000000000000000000000007213 114.0
HKD1_k127_5612155_15 DUF167 K09131 - - 0.00000000000000001026 91.0
HKD1_k127_5612155_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00001012 54.0
HKD1_k127_5612155_17 PAS fold - - - 0.0002145 49.0
HKD1_k127_5612155_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 438.0
HKD1_k127_5612155_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 360.0
HKD1_k127_5612155_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001375 278.0
HKD1_k127_5612155_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000005457 259.0
HKD1_k127_5612155_6 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005824 248.0
HKD1_k127_5612155_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000003529 231.0
HKD1_k127_5612155_8 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000000000000000002597 208.0
HKD1_k127_5612155_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000112 213.0
HKD1_k127_5705960_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
HKD1_k127_5705960_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 312.0
HKD1_k127_5705960_2 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000001972 222.0
HKD1_k127_5705960_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000004506 194.0
HKD1_k127_5705960_4 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000003931 181.0
HKD1_k127_5705960_5 Uncharacterized lipoprotein K07286 - - 0.000000000000000000000000000000002174 136.0
HKD1_k127_5705960_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000002145 124.0
HKD1_k127_5705960_7 Cbs domain K04767 - - 0.0000000000000000000000005665 121.0
HKD1_k127_5705960_8 Peptidase family U32 K08303 - - 0.0000003157 54.0
HKD1_k127_5776737_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 435.0
HKD1_k127_5776737_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 285.0
HKD1_k127_5776737_2 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000006877 164.0
HKD1_k127_5776737_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000005489 171.0
HKD1_k127_5776737_4 - - - - 0.00003169 54.0
HKD1_k127_5782500_0 General secretory system II, protein E domain protein K02652 - - 6.592e-237 744.0
HKD1_k127_5782500_1 SMART Elongator protein 3 MiaB NifB - - - 5.802e-213 689.0
HKD1_k127_5782500_10 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 243.0
HKD1_k127_5782500_11 HD domain K07814 - - 0.000000000000000000000000000000000000000000002264 181.0
HKD1_k127_5782500_12 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000265 173.0
HKD1_k127_5782500_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000001747 164.0
HKD1_k127_5782500_14 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000006716 99.0
HKD1_k127_5782500_15 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000005176 67.0
HKD1_k127_5782500_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 581.0
HKD1_k127_5782500_3 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 573.0
HKD1_k127_5782500_4 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 505.0
HKD1_k127_5782500_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 430.0
HKD1_k127_5782500_6 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 428.0
HKD1_k127_5782500_7 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000315 284.0
HKD1_k127_5782500_8 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002969 279.0
HKD1_k127_5782500_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001604 259.0
HKD1_k127_5922527_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 3.276e-227 716.0
HKD1_k127_5922527_1 AMP-binding enzyme C-terminal domain - - - 2.043e-223 702.0
HKD1_k127_5922527_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 557.0
HKD1_k127_5922527_3 extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005163 278.0
HKD1_k127_5922527_4 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000002581 160.0
HKD1_k127_5922527_5 4Fe-4S binding domain - - - 0.0000000000000000001457 100.0
HKD1_k127_5922527_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000001159 59.0
HKD1_k127_6038327_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 445.0
HKD1_k127_6038327_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 442.0
HKD1_k127_6038327_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 445.0
HKD1_k127_6038327_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 317.0
HKD1_k127_6038327_4 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 295.0
HKD1_k127_6038327_5 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000006074 252.0
HKD1_k127_6038327_6 - - - - 0.00000002303 67.0
HKD1_k127_6058892_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0 1348.0
HKD1_k127_6058892_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 8.511e-222 698.0
HKD1_k127_6058892_10 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 437.0
HKD1_k127_6058892_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 414.0
HKD1_k127_6058892_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 355.0
HKD1_k127_6058892_13 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
HKD1_k127_6058892_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 336.0
HKD1_k127_6058892_15 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 350.0
HKD1_k127_6058892_16 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD1_k127_6058892_17 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
HKD1_k127_6058892_18 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006105 282.0
HKD1_k127_6058892_19 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001998 265.0
HKD1_k127_6058892_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.462e-221 711.0
HKD1_k127_6058892_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000004078 218.0
HKD1_k127_6058892_21 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000232 194.0
HKD1_k127_6058892_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000006461 194.0
HKD1_k127_6058892_23 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000001133 180.0
HKD1_k127_6058892_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000001129 173.0
HKD1_k127_6058892_25 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000001403 188.0
HKD1_k127_6058892_26 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000183 162.0
HKD1_k127_6058892_27 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000000000000000001197 156.0
HKD1_k127_6058892_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000006075 145.0
HKD1_k127_6058892_29 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000001055 148.0
HKD1_k127_6058892_3 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 2.851e-220 693.0
HKD1_k127_6058892_30 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000001982 139.0
HKD1_k127_6058892_31 Diguanylate cyclase - - - 0.0000000000000000000000000000000005675 143.0
HKD1_k127_6058892_32 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.00000000000000000000000001407 123.0
HKD1_k127_6058892_33 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000001746 118.0
HKD1_k127_6058892_34 Smr domain - - - 0.00000000000000000000000009614 109.0
HKD1_k127_6058892_35 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000001849 122.0
HKD1_k127_6058892_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000001106 106.0
HKD1_k127_6058892_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000002702 106.0
HKD1_k127_6058892_38 Rhomboid family - - - 0.000000000000000000005538 107.0
HKD1_k127_6058892_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000001524 99.0
HKD1_k127_6058892_4 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 5.703e-201 648.0
HKD1_k127_6058892_40 methyltransferase activity - - - 0.0000000000000000002595 100.0
HKD1_k127_6058892_41 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000007112 94.0
HKD1_k127_6058892_5 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.056e-195 623.0
HKD1_k127_6058892_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 518.0
HKD1_k127_6058892_7 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 497.0
HKD1_k127_6058892_8 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 476.0
HKD1_k127_6058892_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 443.0
HKD1_k127_6068666_0 Receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 599.0
HKD1_k127_6068666_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 593.0
HKD1_k127_6068666_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 378.0
HKD1_k127_6068666_3 TM2 domain - - - 0.000000000000000000000000000499 118.0
HKD1_k127_6072078_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 492.0
HKD1_k127_6072078_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 444.0
HKD1_k127_6072078_10 cytochrome c biogenesis protein - - - 0.00000000000000000000001235 116.0
HKD1_k127_6072078_11 RDD family - - - 0.00000000000000000007506 96.0
HKD1_k127_6072078_12 CHASE - - - 0.0000000000001307 85.0
HKD1_k127_6072078_14 cAMP biosynthetic process - - - 0.0007921 51.0
HKD1_k127_6072078_2 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HKD1_k127_6072078_3 Histidine kinase A domain protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 312.0
HKD1_k127_6072078_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000005139 209.0
HKD1_k127_6072078_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000001111 209.0
HKD1_k127_6072078_6 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000004 209.0
HKD1_k127_6072078_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000003875 196.0
HKD1_k127_6072078_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000517 175.0
HKD1_k127_6072078_9 cytochrome complex assembly - - - 0.00000000000000000000000000000000000002691 154.0
HKD1_k127_6109163_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1582.0
HKD1_k127_6109163_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 470.0
HKD1_k127_6109163_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
HKD1_k127_6109163_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000001834 164.0
HKD1_k127_6109163_4 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000001063 74.0
HKD1_k127_6119576_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1202.0
HKD1_k127_6119576_1 metallopeptidase activity K01218,K13276 - 3.2.1.78 7.884e-288 921.0
HKD1_k127_6119576_2 PAS PAC sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 624.0
HKD1_k127_6119576_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 447.0
HKD1_k127_6119576_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000001592 211.0
HKD1_k127_6119576_5 chlorophyll binding K03286,K03640 - - 0.000000000000000000000000000000000000000000000000000000006857 213.0
HKD1_k127_6119576_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000000000000000000000000000004235 203.0
HKD1_k127_6119576_7 Domain of unknown function (DUF386) - - - 0.000000000000000000000000000000000000000000001011 172.0
HKD1_k127_6124279_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.718e-306 980.0
HKD1_k127_6124279_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 509.0
HKD1_k127_6124279_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 334.0
HKD1_k127_6124279_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
HKD1_k127_6124279_4 cytochrome C family protein - - - 0.0000000000000000000000000000000000002111 147.0
HKD1_k127_6139875_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 4.384e-200 631.0
HKD1_k127_6139875_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 578.0
HKD1_k127_6139875_10 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
HKD1_k127_6139875_11 isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 316.0
HKD1_k127_6139875_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
HKD1_k127_6139875_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 295.0
HKD1_k127_6139875_14 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 295.0
HKD1_k127_6139875_15 Calcineurin-like phosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
HKD1_k127_6139875_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000003799 250.0
HKD1_k127_6139875_17 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000077 232.0
HKD1_k127_6139875_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000359 244.0
HKD1_k127_6139875_19 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000001052 227.0
HKD1_k127_6139875_2 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 535.0
HKD1_k127_6139875_20 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000006361 217.0
HKD1_k127_6139875_21 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000007551 216.0
HKD1_k127_6139875_22 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000008601 202.0
HKD1_k127_6139875_23 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000153 190.0
HKD1_k127_6139875_24 - - - - 0.0000000000000000000000000000000000000000001484 179.0
HKD1_k127_6139875_25 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000002544 158.0
HKD1_k127_6139875_26 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000004011 151.0
HKD1_k127_6139875_28 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000004504 135.0
HKD1_k127_6139875_29 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000005169 117.0
HKD1_k127_6139875_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 516.0
HKD1_k127_6139875_30 cytochrome c - - - 0.00000000000000000000002965 112.0
HKD1_k127_6139875_31 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000002409 106.0
HKD1_k127_6139875_32 Dodecin K09165 - - 0.00000000000000000003109 95.0
HKD1_k127_6139875_33 peroxiredoxin activity - - - 0.00000000000000000011 102.0
HKD1_k127_6139875_34 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000575 89.0
HKD1_k127_6139875_35 Protein of unknown function (DUF3341) - - - 0.000000000000000001099 94.0
HKD1_k127_6139875_36 2-Nitropropane dioxygenase - - - 0.00000000000000004388 96.0
HKD1_k127_6139875_38 - - - - 0.0000000000000004049 90.0
HKD1_k127_6139875_39 Putative regulatory protein - - - 0.0000000000000316 75.0
HKD1_k127_6139875_4 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 520.0
HKD1_k127_6139875_40 Glutamine amidotransferases class-II K07008 - 3.5.1.118 0.00000000009106 72.0
HKD1_k127_6139875_5 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 424.0
HKD1_k127_6139875_6 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 381.0
HKD1_k127_6139875_7 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 389.0
HKD1_k127_6139875_8 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 346.0
HKD1_k127_6139875_9 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 332.0
HKD1_k127_6176563_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 534.0
HKD1_k127_6176563_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 462.0
HKD1_k127_6176563_10 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 340.0
HKD1_k127_6176563_11 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 329.0
HKD1_k127_6176563_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000009077 293.0
HKD1_k127_6176563_13 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001782 256.0
HKD1_k127_6176563_14 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000001521 233.0
HKD1_k127_6176563_15 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000001759 194.0
HKD1_k127_6176563_16 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000003254 186.0
HKD1_k127_6176563_17 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000003405 171.0
HKD1_k127_6176563_18 transcriptional regulator - - - 0.00000000000000000000000000000000000000006762 158.0
HKD1_k127_6176563_19 Haem-degrading - - - 0.00000000000000000000000000000000435 138.0
HKD1_k127_6176563_2 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 462.0
HKD1_k127_6176563_20 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000512 134.0
HKD1_k127_6176563_21 peroxiredoxin activity K02199 - - 0.00000000000000000000000005353 119.0
HKD1_k127_6176563_22 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.0000000000000000000002454 104.0
HKD1_k127_6176563_23 Cupin 2 conserved barrel domain - - - 0.0000000000000000000003335 111.0
HKD1_k127_6176563_24 Uncharacterised protein family UPF0047 - - - 0.000000000369 67.0
HKD1_k127_6176563_25 - - - - 0.0000002242 58.0
HKD1_k127_6176563_26 SMART Rhodanese domain protein - - - 0.0000017 50.0
HKD1_k127_6176563_27 Uncharacterised protein family UPF0047 - - - 0.00001005 58.0
HKD1_k127_6176563_28 - - - - 0.00002109 56.0
HKD1_k127_6176563_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 418.0
HKD1_k127_6176563_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 432.0
HKD1_k127_6176563_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 438.0
HKD1_k127_6176563_6 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 396.0
HKD1_k127_6176563_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
HKD1_k127_6176563_8 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 358.0
HKD1_k127_6176563_9 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 359.0
HKD1_k127_6189292_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1273.0
HKD1_k127_6189292_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1271.0
HKD1_k127_6189292_10 - - - - 0.00006445 51.0
HKD1_k127_6189292_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 4.029e-220 694.0
HKD1_k127_6189292_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 404.0
HKD1_k127_6189292_4 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 372.0
HKD1_k127_6189292_5 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000002886 252.0
HKD1_k127_6189292_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000001716 244.0
HKD1_k127_6189292_7 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001221 239.0
HKD1_k127_6189292_8 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.0000000000000000000000000000000000000000000000008616 190.0
HKD1_k127_6189292_9 Cold shock K03704 - - 0.00000000000000000000000001379 114.0
HKD1_k127_6229251_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 5.308e-195 622.0
HKD1_k127_6229251_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 379.0
HKD1_k127_6229251_2 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000001942 226.0
HKD1_k127_6229251_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001283 217.0
HKD1_k127_6229251_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000004908 170.0
HKD1_k127_6229251_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000009418 140.0
HKD1_k127_6229251_6 thioesterase K07107 - - 0.000000000000000000000000001028 118.0
HKD1_k127_6229251_7 PFAM peptidase K08303 - - 0.000000000000000000000004297 114.0
HKD1_k127_6229251_8 PFAM Class III cytochrome C family - - - 0.000000000000002064 80.0
HKD1_k127_6337758_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 528.0
HKD1_k127_6337758_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001663 254.0
HKD1_k127_6337758_3 spore germination - - - 0.000000000000000000000000007117 119.0
HKD1_k127_6337758_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000007516 100.0
HKD1_k127_6337758_5 membrane K08978 - - 0.00000000000001111 79.0
HKD1_k127_6337758_6 - - - - 0.0000105 52.0
HKD1_k127_6390603_0 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 481.0
HKD1_k127_6390603_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 424.0
HKD1_k127_6390603_10 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000009735 173.0
HKD1_k127_6390603_11 metalloendopeptidase activity K03799 - - 0.00000000000000000000000001607 121.0
HKD1_k127_6390603_12 Lipoprotein - - - 0.0000000000274 73.0
HKD1_k127_6390603_13 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000005582 63.0
HKD1_k127_6390603_17 - - - - 0.000007489 54.0
HKD1_k127_6390603_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 347.0
HKD1_k127_6390603_3 Ribonuclease E/G family K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 383.0
HKD1_k127_6390603_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 316.0
HKD1_k127_6390603_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 312.0
HKD1_k127_6390603_6 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 307.0
HKD1_k127_6390603_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000104 242.0
HKD1_k127_6390603_8 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000001897 211.0
HKD1_k127_6390603_9 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000002937 206.0
HKD1_k127_6514733_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 3.674e-280 869.0
HKD1_k127_6514733_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 607.0
HKD1_k127_6514733_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 278.0
HKD1_k127_6514733_11 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001455 259.0
HKD1_k127_6514733_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001054 224.0
HKD1_k127_6514733_13 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000004982 177.0
HKD1_k127_6514733_14 - - - - 0.00000000000000000000000000000000000000004152 165.0
HKD1_k127_6514733_15 domain, Protein - - - 0.00000000000000000000000009652 123.0
HKD1_k127_6514733_16 Universal stress protein family - - - 0.0000000000000000000002925 103.0
HKD1_k127_6514733_17 Diguanylate cyclase - - - 0.0000000000000000000003532 109.0
HKD1_k127_6514733_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000005989 102.0
HKD1_k127_6514733_19 ATP synthase, subunit C K02124 - - 0.000000000002366 72.0
HKD1_k127_6514733_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 515.0
HKD1_k127_6514733_20 subunit (C K02119 - - 0.0000000001893 74.0
HKD1_k127_6514733_21 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000002969 55.0
HKD1_k127_6514733_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000007113 58.0
HKD1_k127_6514733_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0001036 52.0
HKD1_k127_6514733_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 530.0
HKD1_k127_6514733_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 457.0
HKD1_k127_6514733_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 417.0
HKD1_k127_6514733_6 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 366.0
HKD1_k127_6514733_7 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 368.0
HKD1_k127_6514733_8 Belongs to the pseudouridine synthase RluA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 359.0
HKD1_k127_6514733_9 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 336.0
HKD1_k127_66677_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 612.0
HKD1_k127_66677_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 545.0
HKD1_k127_66677_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000002327 217.0
HKD1_k127_66677_11 - - - - 0.0000000000000000000000000000000000000000000003079 189.0
HKD1_k127_66677_12 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000002787 71.0
HKD1_k127_66677_13 PFAM Colicin V production protein K03558 - - 0.0000008759 59.0
HKD1_k127_66677_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 430.0
HKD1_k127_66677_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 389.0
HKD1_k127_66677_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 415.0
HKD1_k127_66677_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 383.0
HKD1_k127_66677_6 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 400.0
HKD1_k127_66677_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 308.0
HKD1_k127_66677_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001667 290.0
HKD1_k127_66677_9 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005046 280.0
HKD1_k127_6693206_0 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 416.0
HKD1_k127_6693206_1 transport, permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001055 275.0
HKD1_k127_6693206_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002585 282.0
HKD1_k127_6693206_3 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
HKD1_k127_6693206_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000003665 218.0
HKD1_k127_6693206_5 Glycosyl transferase 4-like domain - - - 0.00000000000000000001002 108.0
HKD1_k127_6693206_6 COG0110 Acetyltransferase (isoleucine patch superfamily) K00661 - 2.3.1.79 0.000000000000000001692 101.0
HKD1_k127_6702809_0 PFAM AMP-dependent synthetase and ligase - - - 2.89e-204 657.0
HKD1_k127_6702809_1 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 523.0
HKD1_k127_6702809_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 436.0
HKD1_k127_6702809_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 360.0
HKD1_k127_6702809_4 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 291.0
HKD1_k127_6702809_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003268 269.0
HKD1_k127_6702809_6 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000005712 231.0
HKD1_k127_6702809_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000009884 216.0
HKD1_k127_6702809_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000004149 89.0
HKD1_k127_6702809_9 - - - - 0.00001342 56.0
HKD1_k127_6744089_0 Elongator protein 3, MiaB family, Radical SAM - - - 5.884e-198 632.0
HKD1_k127_6744089_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 493.0
HKD1_k127_6744089_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 388.0
HKD1_k127_6744089_3 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 375.0
HKD1_k127_6744089_4 - - - - 0.0000000007086 61.0
HKD1_k127_6744089_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00002046 53.0
HKD1_k127_6856208_0 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 3.184e-227 710.0
HKD1_k127_6856208_1 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 552.0
HKD1_k127_6856208_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000005147 151.0
HKD1_k127_6856208_11 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000002418 104.0
HKD1_k127_6856208_12 TonB C terminal K03832 - - 0.0000000002706 72.0
HKD1_k127_6856208_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
HKD1_k127_6856208_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 329.0
HKD1_k127_6856208_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 284.0
HKD1_k127_6856208_5 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 259.0
HKD1_k127_6856208_6 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000106 194.0
HKD1_k127_6856208_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000004119 178.0
HKD1_k127_6856208_8 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000000002383 167.0
HKD1_k127_6856208_9 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000002092 148.0
HKD1_k127_6901583_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006937 280.0
HKD1_k127_6901583_1 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000004296 225.0
HKD1_k127_6901583_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000002668 189.0
HKD1_k127_6901583_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00003569 48.0
HKD1_k127_6963608_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 528.0
HKD1_k127_6963608_1 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 523.0
HKD1_k127_6963608_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000107 246.0
HKD1_k127_6963608_11 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000006066 188.0
HKD1_k127_6963608_12 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.00000000000000000000000002924 115.0
HKD1_k127_6963608_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 501.0
HKD1_k127_6963608_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 456.0
HKD1_k127_6963608_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 389.0
HKD1_k127_6963608_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
HKD1_k127_6963608_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 346.0
HKD1_k127_6963608_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 270.0
HKD1_k127_6963608_8 radical SAM domain protein K15045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 289.0
HKD1_k127_6963608_9 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008886 283.0
HKD1_k127_7011132_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000004003 181.0
HKD1_k127_7011132_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000001134 130.0
HKD1_k127_7011132_2 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000001731 111.0
HKD1_k127_7011132_3 endonuclease containing a URI domain K07461 - - 0.00000000000000001149 92.0
HKD1_k127_7049589_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.571e-264 850.0
HKD1_k127_7049589_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 579.0
HKD1_k127_7049589_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000146 198.0
HKD1_k127_7049589_11 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000003846 168.0
HKD1_k127_7049589_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000002154 170.0
HKD1_k127_7049589_13 Sensory domain found in PocR - - - 0.000000000000000000000000000002644 132.0
HKD1_k127_7049589_14 MFS_1 like family - - - 0.000000000000000000000000001923 126.0
HKD1_k127_7049589_15 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000002373 79.0
HKD1_k127_7049589_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000002475 81.0
HKD1_k127_7049589_17 PFAM glutaredoxin K18917 - 1.20.4.3 0.0000000000006928 80.0
HKD1_k127_7049589_18 Putative regulatory protein - - - 0.000000004304 62.0
HKD1_k127_7049589_19 Pfam:DUF1049 - - - 0.00002933 56.0
HKD1_k127_7049589_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 486.0
HKD1_k127_7049589_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 436.0
HKD1_k127_7049589_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000007586 266.0
HKD1_k127_7049589_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000002333 275.0
HKD1_k127_7049589_6 Dimerisation domain of Zinc Transporter K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001121 263.0
HKD1_k127_7049589_7 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002807 260.0
HKD1_k127_7049589_8 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002787 258.0
HKD1_k127_7049589_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
HKD1_k127_7131329_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.117e-289 899.0
HKD1_k127_7131329_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 5.975e-214 692.0
HKD1_k127_7131329_10 Formyl transferase, C-terminal domain K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 322.0
HKD1_k127_7131329_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 327.0
HKD1_k127_7131329_12 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 294.0
HKD1_k127_7131329_13 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000008135 261.0
HKD1_k127_7131329_14 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000003773 237.0
HKD1_k127_7131329_15 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000002244 214.0
HKD1_k127_7131329_16 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000006925 203.0
HKD1_k127_7131329_17 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000009042 207.0
HKD1_k127_7131329_18 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000001078 190.0
HKD1_k127_7131329_19 NUDIX domain - - - 0.00000000000000000000000000000000000000000003489 166.0
HKD1_k127_7131329_2 PFAM response regulator receiver K11384 - - 4.406e-210 661.0
HKD1_k127_7131329_20 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000001472 133.0
HKD1_k127_7131329_21 PFAM ROSMUCR transcriptional regulator - - - 0.000000000000000000000000007606 115.0
HKD1_k127_7131329_22 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000127 113.0
HKD1_k127_7131329_23 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000003841 113.0
HKD1_k127_7131329_24 PBS lyase HEAT-like repeat - - - 0.000000000001881 81.0
HKD1_k127_7131329_25 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000004006 64.0
HKD1_k127_7131329_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 462.0
HKD1_k127_7131329_4 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 440.0
HKD1_k127_7131329_5 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 407.0
HKD1_k127_7131329_6 Belongs to the DegT DnrJ EryC1 family K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 390.0
HKD1_k127_7131329_7 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 363.0
HKD1_k127_7131329_8 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 351.0
HKD1_k127_7131329_9 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 314.0
HKD1_k127_7217892_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.133e-202 645.0
HKD1_k127_7217892_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.61e-201 651.0
HKD1_k127_7217892_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
HKD1_k127_7217892_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000005818 218.0
HKD1_k127_7217892_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000006558 209.0
HKD1_k127_7217892_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004343 208.0
HKD1_k127_7217892_14 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000004922 208.0
HKD1_k127_7217892_15 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004693 204.0
HKD1_k127_7217892_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001289 196.0
HKD1_k127_7217892_17 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002086 187.0
HKD1_k127_7217892_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000008135 169.0
HKD1_k127_7217892_19 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001759 171.0
HKD1_k127_7217892_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 437.0
HKD1_k127_7217892_20 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000006134 158.0
HKD1_k127_7217892_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000641 151.0
HKD1_k127_7217892_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000008031 149.0
HKD1_k127_7217892_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000438 144.0
HKD1_k127_7217892_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000003578 138.0
HKD1_k127_7217892_25 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000005833 127.0
HKD1_k127_7217892_26 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000002377 128.0
HKD1_k127_7217892_27 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000001864 121.0
HKD1_k127_7217892_28 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000002708 120.0
HKD1_k127_7217892_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001257 115.0
HKD1_k127_7217892_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 396.0
HKD1_k127_7217892_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003476 113.0
HKD1_k127_7217892_31 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003653 106.0
HKD1_k127_7217892_32 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000315 72.0
HKD1_k127_7217892_33 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000006459 68.0
HKD1_k127_7217892_34 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000004471 68.0
HKD1_k127_7217892_35 Ribosomal protein L30p/L7e K02907 - - 0.00000000006987 71.0
HKD1_k127_7217892_37 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0008132 49.0
HKD1_k127_7217892_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 317.0
HKD1_k127_7217892_5 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
HKD1_k127_7217892_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 305.0
HKD1_k127_7217892_7 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 303.0
HKD1_k127_7217892_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
HKD1_k127_7217892_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000352 276.0
HKD1_k127_7254227_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.873e-210 676.0
HKD1_k127_7254227_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 466.0
HKD1_k127_7254227_10 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000007219 89.0
HKD1_k127_7254227_11 Peptidase family M23 K21471 - - 0.0000000000000001453 93.0
HKD1_k127_7254227_12 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000002571 80.0
HKD1_k127_7254227_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002782 72.0
HKD1_k127_7254227_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 379.0
HKD1_k127_7254227_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 312.0
HKD1_k127_7254227_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001715 261.0
HKD1_k127_7254227_5 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002965 259.0
HKD1_k127_7254227_6 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000004179 224.0
HKD1_k127_7254227_7 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000001113 181.0
HKD1_k127_7254227_8 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000454 147.0
HKD1_k127_7254227_9 - - - - 0.000000000000000000000000004667 113.0
HKD1_k127_7256875_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1436.0
HKD1_k127_7256875_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 552.0
HKD1_k127_7256875_10 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000001464 228.0
HKD1_k127_7256875_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000005455 224.0
HKD1_k127_7256875_12 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000005975 184.0
HKD1_k127_7256875_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000002494 177.0
HKD1_k127_7256875_14 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000003622 172.0
HKD1_k127_7256875_16 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.00000000000000000000000001553 118.0
HKD1_k127_7256875_17 PFAM Forkhead-associated protein - - - 0.00000000002748 72.0
HKD1_k127_7256875_18 Major Facilitator Superfamily K08218 - - 0.00000003681 56.0
HKD1_k127_7256875_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 499.0
HKD1_k127_7256875_3 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 407.0
HKD1_k127_7256875_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 371.0
HKD1_k127_7256875_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 319.0
HKD1_k127_7256875_6 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 312.0
HKD1_k127_7256875_7 Prokaryotic cytochrome b561 K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
HKD1_k127_7256875_8 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 279.0
HKD1_k127_7256875_9 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
HKD1_k127_7257430_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1604.0
HKD1_k127_7257430_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.487e-309 956.0
HKD1_k127_7257430_10 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 387.0
HKD1_k127_7257430_11 metal-dependent phosphohydrolase HD region K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 355.0
HKD1_k127_7257430_12 Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001616 272.0
HKD1_k127_7257430_13 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000182 256.0
HKD1_k127_7257430_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
HKD1_k127_7257430_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003273 258.0
HKD1_k127_7257430_16 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
HKD1_k127_7257430_17 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000000000000000002012 179.0
HKD1_k127_7257430_18 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000000000000000000000000000000689 178.0
HKD1_k127_7257430_19 Chorismate mutase K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000001855 157.0
HKD1_k127_7257430_2 Citrate lyase, alpha subunit (CitF) - - - 4.308e-280 877.0
HKD1_k127_7257430_20 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000006059 168.0
HKD1_k127_7257430_21 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000001651 147.0
HKD1_k127_7257430_22 - - - - 0.000000000000000000000000000001512 128.0
HKD1_k127_7257430_23 - - - - 0.000000000000000000000000000008258 126.0
HKD1_k127_7257430_24 - - - - 0.0000000000000000000000000008665 127.0
HKD1_k127_7257430_25 Haemolytic - - - 0.0000000000000000000000001107 111.0
HKD1_k127_7257430_26 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000001896 101.0
HKD1_k127_7257430_3 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 621.0
HKD1_k127_7257430_4 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 584.0
HKD1_k127_7257430_5 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 573.0
HKD1_k127_7257430_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 547.0
HKD1_k127_7257430_7 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 504.0
HKD1_k127_7257430_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 479.0
HKD1_k127_7257430_9 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 443.0
HKD1_k127_7282541_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004615 259.0
HKD1_k127_7282541_1 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000001938 131.0
HKD1_k127_7282541_2 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000006225 137.0
HKD1_k127_7282541_3 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.0000000000000000000000004046 122.0
HKD1_k127_7286440_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 306.0
HKD1_k127_7286440_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000027 234.0
HKD1_k127_7286440_2 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000002669 208.0
HKD1_k127_7286440_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000009349 171.0
HKD1_k127_7286440_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000002267 153.0
HKD1_k127_7286440_5 Ketopantoate hydroxymethyltransferase K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.00000009989 53.0
HKD1_k127_7326535_0 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 483.0
HKD1_k127_7326535_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 451.0
HKD1_k127_7326535_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 431.0
HKD1_k127_7326535_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000004293 239.0
HKD1_k127_7326535_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000002679 184.0
HKD1_k127_7326535_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000002713 143.0
HKD1_k127_7326535_6 Protein of unknown function (DUF2905) - - - 0.0000000000000006609 87.0
HKD1_k127_7326535_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000002869 74.0
HKD1_k127_7326535_8 Domain of unknown function (DUF4390) - - - 0.000000002187 66.0
HKD1_k127_7393739_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 436.0
HKD1_k127_7393739_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 414.0
HKD1_k127_7393739_2 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
HKD1_k127_7393739_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 386.0
HKD1_k127_7393739_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 302.0
HKD1_k127_7393739_5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
HKD1_k127_7393739_6 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000001403 190.0
HKD1_k127_7393739_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000002678 196.0
HKD1_k127_7393739_9 THUMP - - - 0.00000000000000000000000003692 120.0
HKD1_k127_7442841_0 FtsX-like permease family K02004 - - 1.629e-260 825.0
HKD1_k127_7442841_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 606.0
HKD1_k127_7442841_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 390.0
HKD1_k127_7442841_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 341.0
HKD1_k127_7442841_4 Cache_2 - - - 0.0000000000000000000000000000000000000000000009241 171.0
HKD1_k127_7442841_5 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000005323 134.0
HKD1_k127_7442841_6 - - - - 0.00001736 53.0
HKD1_k127_7460711_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 3.906e-201 653.0
HKD1_k127_7460711_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 329.0
HKD1_k127_7460711_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000003049 194.0
HKD1_k127_7460711_3 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000001406 185.0
HKD1_k127_7460711_4 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000002087 150.0
HKD1_k127_7460711_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000255 143.0
HKD1_k127_7561176_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 571.0
HKD1_k127_7561176_1 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 565.0
HKD1_k127_7561176_2 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 386.0
HKD1_k127_7561176_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
HKD1_k127_7561176_4 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.000000000000000000000000000000000008107 147.0
HKD1_k127_7561176_5 Protein of unknown function (DUF933) K06942 - - 0.0007284 46.0
HKD1_k127_7657598_0 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 522.0
HKD1_k127_7657598_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 356.0
HKD1_k127_7657598_10 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000993 101.0
HKD1_k127_7657598_11 MlaA lipoprotein K04754 - - 0.000000000000000002387 93.0
HKD1_k127_7657598_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 314.0
HKD1_k127_7657598_3 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001736 287.0
HKD1_k127_7657598_4 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003753 268.0
HKD1_k127_7657598_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000007812 175.0
HKD1_k127_7657598_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000002274 178.0
HKD1_k127_7657598_7 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.000000000000000000000000000001551 135.0
HKD1_k127_7657598_8 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000004259 130.0
HKD1_k127_7657598_9 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000001413 118.0
HKD1_k127_76767_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 424.0
HKD1_k127_76767_1 Transketolase, pyrimidine binding domain K00167,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 376.0
HKD1_k127_76767_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 360.0
HKD1_k127_76767_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 342.0
HKD1_k127_76767_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 311.0
HKD1_k127_76767_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000001196 223.0
HKD1_k127_76767_6 HMGL-like K02594 - 2.3.3.14 0.00000000000000000000000000000000000002286 165.0
HKD1_k127_76767_7 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000001439 147.0
HKD1_k127_76767_8 PFAM Nitroreductase K04719,K19286 - 1.13.11.79,1.5.1.39 0.0000000000000000000008337 109.0
HKD1_k127_76767_9 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000002115 66.0
HKD1_k127_7725980_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 557.0
HKD1_k127_7725980_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000009508 230.0
HKD1_k127_7725980_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000009297 77.0
HKD1_k127_7725980_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000004445 66.0
HKD1_k127_7731499_0 Enoyl-CoA hydratase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000636 283.0
HKD1_k127_7731499_1 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003543 274.0
HKD1_k127_7731499_2 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000114 209.0
HKD1_k127_799852_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 406.0
HKD1_k127_799852_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 251.0
HKD1_k127_799852_2 Peptidoglycan-binding LysM - - - 0.000000000000000000000002985 115.0
HKD1_k127_980985_0 PFAM Polysulphide reductase, NrfD K00185 - - 1.489e-213 669.0
HKD1_k127_980985_1 penicillin-binding protein K05367 - 2.4.1.129 8.755e-200 640.0
HKD1_k127_980985_2 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 353.0
HKD1_k127_980985_3 3D domain protein - - - 0.0005911 49.0
HKD1_k127_987997_0 COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, alpha subunit K00169 - 1.2.7.1 1.757e-295 924.0
HKD1_k127_987997_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 9.277e-212 665.0
HKD1_k127_987997_10 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000001692 189.0
HKD1_k127_987997_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.000000000000000000000000000000000000000000000000008189 184.0
HKD1_k127_987997_12 - - - - 0.000000000000000000000000000000000000000000001531 180.0
HKD1_k127_987997_13 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000001568 176.0
HKD1_k127_987997_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000001886 129.0
HKD1_k127_987997_15 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000009062 123.0
HKD1_k127_987997_16 Protein of unknown function (DUF3106) - - - 0.00000001565 66.0
HKD1_k127_987997_17 Putative zinc-finger - - - 0.0000006885 59.0
HKD1_k127_987997_2 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 365.0
HKD1_k127_987997_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 365.0
HKD1_k127_987997_4 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 320.0
HKD1_k127_987997_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 338.0
HKD1_k127_987997_6 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
HKD1_k127_987997_7 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004692 302.0
HKD1_k127_987997_8 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000006565 250.0
HKD1_k127_987997_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0