Overview

ID MAG01727
Name HKD1_bin.45
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family DATFVB01
Genus DATFVB01
Species
Assembly information
Completeness (%) 93.33
Contamination (%) 0.46
GC content (%) 71.0
N50 (bp) 9,634
Genome size (bp) 3,644,729

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3130

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1010863_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.548e-259 829.0
HKD1_k127_1010863_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000001741 151.0
HKD1_k127_1010863_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000003385 104.0
HKD1_k127_1010863_3 Hsp20/alpha crystallin family - - - 0.000000000000004102 84.0
HKD1_k127_1010863_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00004545 56.0
HKD1_k127_1013575_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000003378 239.0
HKD1_k127_1013575_1 Regulatory protein, FmdB family - - - 0.00000000000005052 83.0
HKD1_k127_1013575_2 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000002199 67.0
HKD1_k127_1022783_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
HKD1_k127_1022783_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
HKD1_k127_1022783_2 Transcriptional regulator - - - 0.000000000002195 73.0
HKD1_k127_1034161_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.852e-241 777.0
HKD1_k127_1034161_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 537.0
HKD1_k127_1034161_10 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001464 256.0
HKD1_k127_1034161_11 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000004589 259.0
HKD1_k127_1034161_12 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000002873 173.0
HKD1_k127_1034161_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000001135 146.0
HKD1_k127_1034161_14 MlaD protein K02067 - - 0.0000000000000000000000000000003753 141.0
HKD1_k127_1034161_15 Domain of unknown function (DUF2383) - - - 0.00000000000000000000003773 106.0
HKD1_k127_1034161_16 Domain of unknown function (DUF2383) - - - 0.00000000000000009618 87.0
HKD1_k127_1034161_17 Domain of unknown function (DUF202) K00389 - - 0.0000000000000004714 91.0
HKD1_k127_1034161_18 peptidyl-tyrosine sulfation - - - 0.0000000000000006949 85.0
HKD1_k127_1034161_19 cellulose binding - - - 0.000000000000002353 81.0
HKD1_k127_1034161_2 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 542.0
HKD1_k127_1034161_20 phosphorelay signal transduction system - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001127 74.0
HKD1_k127_1034161_21 Leucine-rich repeat (LRR) protein K13730 - - 0.00027 53.0
HKD1_k127_1034161_3 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 526.0
HKD1_k127_1034161_4 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 518.0
HKD1_k127_1034161_5 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 519.0
HKD1_k127_1034161_6 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 370.0
HKD1_k127_1034161_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 360.0
HKD1_k127_1034161_8 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 365.0
HKD1_k127_1034161_9 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001119 266.0
HKD1_k127_1036816_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 348.0
HKD1_k127_1038167_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 437.0
HKD1_k127_1038167_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000001565 204.0
HKD1_k127_1039407_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 334.0
HKD1_k127_1039407_1 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000214 145.0
HKD1_k127_1041070_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003191 268.0
HKD1_k127_1041070_1 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000005616 209.0
HKD1_k127_1048669_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 449.0
HKD1_k127_1048669_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000001673 81.0
HKD1_k127_1049239_0 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000001222 268.0
HKD1_k127_1049239_1 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000002739 136.0
HKD1_k127_1049423_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 427.0
HKD1_k127_1049423_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002149 242.0
HKD1_k127_1049423_2 KR domain - - - 0.0000000000000000000000000000000000000000000000001413 180.0
HKD1_k127_1049423_3 - - - - 0.0000000036 62.0
HKD1_k127_1054716_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 358.0
HKD1_k127_1054716_1 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002771 248.0
HKD1_k127_1054716_2 - - - - 0.0000002485 59.0
HKD1_k127_105478_0 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000852 185.0
HKD1_k127_105478_1 STAS domain K04749 - - 0.00000000000000000000000000000007082 130.0
HKD1_k127_105478_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000004023 113.0
HKD1_k127_105478_3 Zn peptidase - - - 0.000000000000000000000007523 115.0
HKD1_k127_1061314_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 488.0
HKD1_k127_1061314_1 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 382.0
HKD1_k127_1061314_2 PFAM Redoxin - - - 0.0000001802 53.0
HKD1_k127_1061314_3 Carboxypeptidase regulatory-like domain - - - 0.0000003513 64.0
HKD1_k127_1062635_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 428.0
HKD1_k127_1062635_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 349.0
HKD1_k127_1062635_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
HKD1_k127_1062635_3 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000001281 190.0
HKD1_k127_1075014_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 490.0
HKD1_k127_1075014_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000004849 220.0
HKD1_k127_1075014_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000002072 150.0
HKD1_k127_1075014_3 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000007516 139.0
HKD1_k127_1075014_4 Belongs to the glycosyl hydrolase 32 family - - - 0.00000000000000000000000000006845 136.0
HKD1_k127_1075014_5 Cupin domain - - - 0.000000000000000000000000007518 118.0
HKD1_k127_1075014_6 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000004997 100.0
HKD1_k127_1075014_7 - - - - 0.000000000000001187 86.0
HKD1_k127_1075014_8 restriction endonuclease - - - 0.0000000000006313 75.0
HKD1_k127_1075014_9 fatty acid desaturase transmembrane protein - - - 0.0000000000009037 80.0
HKD1_k127_1077230_0 amino acid transport K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 499.0
HKD1_k127_1077230_1 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 466.0
HKD1_k127_1077230_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000001489 88.0
HKD1_k127_1077230_11 Cbs domain K04767 - - 0.000000000000000174 86.0
HKD1_k127_1077230_12 Protein of unknown function (DUF3617) - - - 0.0000000000000126 79.0
HKD1_k127_1077230_13 Universal stress protein - - - 0.0000000000001298 83.0
HKD1_k127_1077230_14 Cysteine-rich CPCC - - - 0.00001059 56.0
HKD1_k127_1077230_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
HKD1_k127_1077230_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 404.0
HKD1_k127_1077230_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 321.0
HKD1_k127_1077230_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000002029 263.0
HKD1_k127_1077230_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000113 218.0
HKD1_k127_1077230_7 BON domain - - - 0.000000000000000000000000000000000000000000000000000000001901 210.0
HKD1_k127_1077230_8 - - - - 0.00000000000000000000001696 105.0
HKD1_k127_1077230_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000001012 80.0
HKD1_k127_1092765_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 473.0
HKD1_k127_1092765_1 alcohol dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000134 235.0
HKD1_k127_1092765_2 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000003573 118.0
HKD1_k127_1092765_3 Zinc-binding dehydrogenase - - - 0.0000000000000005606 87.0
HKD1_k127_1092765_4 Dicarboxylate transport - - - 0.000784 52.0
HKD1_k127_1097157_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 287.0
HKD1_k127_1097157_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 255.0
HKD1_k127_1097157_2 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001037 265.0
HKD1_k127_1097157_3 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 239.0
HKD1_k127_1097157_4 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000004497 241.0
HKD1_k127_1097157_5 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000002634 136.0
HKD1_k127_1097157_6 Cupin domain - - - 0.00000000000000004692 85.0
HKD1_k127_1100490_0 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 500.0
HKD1_k127_1100490_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 426.0
HKD1_k127_1100490_10 Polysaccharide export protein K01991,K20988 - - 0.0000000000000000000000000000000000000000000000004634 199.0
HKD1_k127_1100490_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000001593 176.0
HKD1_k127_1100490_12 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000009758 173.0
HKD1_k127_1100490_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000004663 136.0
HKD1_k127_1100490_14 Polysaccharide deacetylase - - - 0.0000000000000002184 83.0
HKD1_k127_1100490_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000005035 63.0
HKD1_k127_1100490_16 O-Antigen ligase - - - 0.00001339 57.0
HKD1_k127_1100490_2 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 394.0
HKD1_k127_1100490_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 352.0
HKD1_k127_1100490_4 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 368.0
HKD1_k127_1100490_5 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 330.0
HKD1_k127_1100490_6 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008809 304.0
HKD1_k127_1100490_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006539 267.0
HKD1_k127_1100490_8 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002065 248.0
HKD1_k127_1100490_9 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000005586 215.0
HKD1_k127_1102136_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 405.0
HKD1_k127_1102136_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 345.0
HKD1_k127_1102136_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 316.0
HKD1_k127_1102136_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001748 289.0
HKD1_k127_1102136_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000001514 251.0
HKD1_k127_1102136_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000007603 85.0
HKD1_k127_1102136_6 Peptidase family M48 - - - 0.00002644 57.0
HKD1_k127_1107040_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 316.0
HKD1_k127_1107040_1 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000002982 202.0
HKD1_k127_1107040_2 - - - - 0.000000000002635 73.0
HKD1_k127_1107040_3 Transport permease protein K01992 - - 0.0008264 43.0
HKD1_k127_1121997_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 572.0
HKD1_k127_1121997_1 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 545.0
HKD1_k127_1121997_10 Methyltransferase domain K15256 - - 0.0003264 50.0
HKD1_k127_1121997_2 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 302.0
HKD1_k127_1121997_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000001668 245.0
HKD1_k127_1121997_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
HKD1_k127_1121997_5 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000127 189.0
HKD1_k127_1121997_6 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000009249 187.0
HKD1_k127_1121997_7 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000002143 115.0
HKD1_k127_1121997_9 synthase - - - 0.0002856 53.0
HKD1_k127_1131510_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000001086 171.0
HKD1_k127_1131510_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000005017 156.0
HKD1_k127_1131510_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000007568 146.0
HKD1_k127_1131510_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000004308 147.0
HKD1_k127_1147594_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1379.0
HKD1_k127_1147594_1 Dienelactone hydrolase family - - - 1.447e-238 758.0
HKD1_k127_1147594_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000004604 62.0
HKD1_k127_1147594_2 phospholipase C K01114 - 3.1.4.3 6.303e-210 668.0
HKD1_k127_1147594_3 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 475.0
HKD1_k127_1147594_4 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 431.0
HKD1_k127_1147594_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 362.0
HKD1_k127_1147594_6 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 329.0
HKD1_k127_1147594_7 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000000000463 200.0
HKD1_k127_1147594_8 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000003739 163.0
HKD1_k127_1147594_9 CBS domain - - - 0.0000000000000000642 89.0
HKD1_k127_1150909_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.653e-217 689.0
HKD1_k127_1150909_1 Cytochrome c - - - 4.661e-198 627.0
HKD1_k127_1150909_10 Signal peptidase, peptidase S26 - - - 0.000000000000000000000000000000000000000000000000003848 196.0
HKD1_k127_1150909_11 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000001826 194.0
HKD1_k127_1150909_12 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000002715 185.0
HKD1_k127_1150909_13 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000005354 189.0
HKD1_k127_1150909_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000002959 168.0
HKD1_k127_1150909_15 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000941 174.0
HKD1_k127_1150909_16 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000005876 157.0
HKD1_k127_1150909_17 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000001434 159.0
HKD1_k127_1150909_18 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000002047 154.0
HKD1_k127_1150909_19 Abc transporter K01990 - - 0.000000000000000000000000000000001596 139.0
HKD1_k127_1150909_2 PFAM cytochrome c assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 477.0
HKD1_k127_1150909_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000008377 120.0
HKD1_k127_1150909_21 CcmB protein K02194 - - 0.00000000000000000000002539 108.0
HKD1_k127_1150909_22 lipoprotein localization to outer membrane K02004 - - 0.00000002971 55.0
HKD1_k127_1150909_23 protein SCO1 SenC K07152 - - 0.0000002131 63.0
HKD1_k127_1150909_24 - - - - 0.00001142 51.0
HKD1_k127_1150909_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 449.0
HKD1_k127_1150909_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 356.0
HKD1_k127_1150909_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000001232 250.0
HKD1_k127_1150909_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000281 242.0
HKD1_k127_1150909_7 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000003717 229.0
HKD1_k127_1150909_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000004083 223.0
HKD1_k127_1150909_9 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000003507 218.0
HKD1_k127_1167174_0 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000007446 237.0
HKD1_k127_1167194_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 371.0
HKD1_k127_1167194_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000001515 78.0
HKD1_k127_1167194_2 domain, Protein - - - 0.0005305 53.0
HKD1_k127_1167658_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 534.0
HKD1_k127_1167658_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 429.0
HKD1_k127_1167658_10 FecR protein - - - 0.0000000000005283 81.0
HKD1_k127_1167658_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 438.0
HKD1_k127_1167658_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 406.0
HKD1_k127_1167658_4 Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006774 287.0
HKD1_k127_1167658_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000018 259.0
HKD1_k127_1167658_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000007857 262.0
HKD1_k127_1167658_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000225 182.0
HKD1_k127_1167658_8 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000683 165.0
HKD1_k127_1167658_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000002984 113.0
HKD1_k127_1185041_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 572.0
HKD1_k127_1185041_1 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 385.0
HKD1_k127_1185041_2 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 344.0
HKD1_k127_1185041_3 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 331.0
HKD1_k127_1185041_4 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000005228 196.0
HKD1_k127_1185041_5 Acetyltransferase (GNAT) domain - - - 0.00001745 50.0
HKD1_k127_1202235_0 - - - - 0.0000000000000000000000000000000001185 140.0
HKD1_k127_1202235_1 - - - - 0.000000000000000000000416 110.0
HKD1_k127_1204083_0 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 300.0
HKD1_k127_1204083_1 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000231 146.0
HKD1_k127_1205122_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 479.0
HKD1_k127_1205122_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 358.0
HKD1_k127_1205122_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004187 284.0
HKD1_k127_1205122_3 VIT family - - - 0.000000000000000000000000000000000000000000007548 170.0
HKD1_k127_121156_0 PFAM Type II secretion system protein E K02652 - - 8.392e-217 685.0
HKD1_k127_121156_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 324.0
HKD1_k127_121156_10 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000003382 157.0
HKD1_k127_121156_11 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000005555 129.0
HKD1_k127_121156_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000001396 102.0
HKD1_k127_121156_13 Pilus assembly protein K02662 - - 0.00000000002049 74.0
HKD1_k127_121156_14 Type II secretory pathway pseudopilin - - - 0.0000003092 62.0
HKD1_k127_121156_15 - - - - 0.0003636 53.0
HKD1_k127_121156_16 PFAM Fimbrial assembly family protein K02663 - - 0.0007118 52.0
HKD1_k127_121156_17 PFAM type II and III secretion system protein K02666 - - 0.0009261 51.0
HKD1_k127_121156_2 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 304.0
HKD1_k127_121156_3 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 315.0
HKD1_k127_121156_4 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
HKD1_k127_121156_5 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000007888 239.0
HKD1_k127_121156_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000001073 198.0
HKD1_k127_121156_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000009772 188.0
HKD1_k127_121156_8 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000006399 187.0
HKD1_k127_121156_9 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.000000000000000000000000000000000000000000007291 184.0
HKD1_k127_1216177_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 5.264e-204 652.0
HKD1_k127_1216177_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000004785 234.0
HKD1_k127_1216177_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000002533 183.0
HKD1_k127_1216177_3 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000000000000000000000000003118 158.0
HKD1_k127_1216177_4 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000005229 121.0
HKD1_k127_1217395_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 501.0
HKD1_k127_1217395_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000006947 131.0
HKD1_k127_121799_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 544.0
HKD1_k127_121799_1 PFAM Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000004382 179.0
HKD1_k127_121799_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000007406 101.0
HKD1_k127_1222345_0 Prolyl oligopeptidase family - - - 6.508e-247 826.0
HKD1_k127_1222345_1 4Fe-4S binding domain - - - 1.698e-238 761.0
HKD1_k127_1222345_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 410.0
HKD1_k127_1222345_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002613 227.0
HKD1_k127_1222345_4 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000004529 229.0
HKD1_k127_1222345_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000008272 149.0
HKD1_k127_1222345_6 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000001642 143.0
HKD1_k127_1222345_7 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000009437 125.0
HKD1_k127_1222345_8 transferase activity, transferring glycosyl groups K19290,K20444,K20534 - 2.4.1.33 0.000000000000000000000001533 116.0
HKD1_k127_1226493_0 PFAM sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 494.0
HKD1_k127_1226493_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 447.0
HKD1_k127_1227379_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 586.0
HKD1_k127_1320950_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 296.0
HKD1_k127_1332375_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1181.0
HKD1_k127_1332375_1 IgA Peptidase M64 - - - 4.871e-202 689.0
HKD1_k127_1332375_2 ATP hydrolysis coupled proton transport K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 330.0
HKD1_k127_1332375_3 collagen metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001552 269.0
HKD1_k127_1332375_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000004202 255.0
HKD1_k127_1332375_5 ATP synthase subunit C K02124 - - 0.000000000000000008997 87.0
HKD1_k127_1332375_6 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000003788 63.0
HKD1_k127_1336975_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 404.0
HKD1_k127_1336975_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 359.0
HKD1_k127_1336975_2 Ribonuclease E/G family K08301 - - 0.00000000000000000008022 93.0
HKD1_k127_1372757_0 Domain of Unknown Function (DUF748) - - - 4.722e-203 674.0
HKD1_k127_1372757_1 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007977 252.0
HKD1_k127_1372757_2 PFAM Fatty acid desaturase K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000001516 210.0
HKD1_k127_1372757_3 peptidoglycan-binding protein - - - 0.00000000000001158 86.0
HKD1_k127_1381634_0 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 7.387e-289 950.0
HKD1_k127_1381634_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 510.0
HKD1_k127_1381634_10 Hemerythrin HHE cation binding domain - - - 0.000000000005704 72.0
HKD1_k127_1381634_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 325.0
HKD1_k127_1381634_3 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000000000000000000001205 254.0
HKD1_k127_1381634_4 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000006958 222.0
HKD1_k127_1381634_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000001773 221.0
HKD1_k127_1381634_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000001084 205.0
HKD1_k127_1381634_7 permease K03548 - - 0.0000000000000000000000000000000000000000003032 178.0
HKD1_k127_1381634_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000038 146.0
HKD1_k127_1381634_9 Predicted membrane protein (DUF2231) - - - 0.000000000000000001972 101.0
HKD1_k127_139286_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 549.0
HKD1_k127_139286_1 - - - - 0.0000000000000000000003764 99.0
HKD1_k127_139286_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000002191 70.0
HKD1_k127_139856_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000001586 221.0
HKD1_k127_139856_1 AntiSigma factor - - - 0.00000000000000000000000000000000000000004944 158.0
HKD1_k127_139856_2 Zincin-like metallopeptidase - - - 0.00000000000000000000006616 112.0
HKD1_k127_1402377_0 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 8.571e-262 824.0
HKD1_k127_1402377_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.909e-202 679.0
HKD1_k127_1402377_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000004545 181.0
HKD1_k127_1402377_3 Helix-hairpin-helix motif - - - 0.0000000000000000009803 101.0
HKD1_k127_1402377_4 - - - - 0.000000000000000004971 98.0
HKD1_k127_1402377_5 amine dehydrogenase activity - - - 0.00000000005817 74.0
HKD1_k127_1402377_6 Outer membrane efflux protein K12340 - - 0.000002003 61.0
HKD1_k127_1402377_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.0001953 55.0
HKD1_k127_1409025_1 PFAM type II and III secretion system protein K02666 - - 0.000006291 57.0
HKD1_k127_1419624_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 612.0
HKD1_k127_1419624_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 552.0
HKD1_k127_1419624_10 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000007116 203.0
HKD1_k127_1419624_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000006593 200.0
HKD1_k127_1419624_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000002309 173.0
HKD1_k127_1419624_13 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000001209 111.0
HKD1_k127_1419624_14 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.000000000000000000000125 101.0
HKD1_k127_1419624_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000007803 67.0
HKD1_k127_1419624_16 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0001367 48.0
HKD1_k127_1419624_17 Polymer-forming cytoskeletal - - - 0.0001699 51.0
HKD1_k127_1419624_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 550.0
HKD1_k127_1419624_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 538.0
HKD1_k127_1419624_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 458.0
HKD1_k127_1419624_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 367.0
HKD1_k127_1419624_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 341.0
HKD1_k127_1419624_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 368.0
HKD1_k127_1419624_8 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 347.0
HKD1_k127_1419624_9 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003341 246.0
HKD1_k127_1445946_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 367.0
HKD1_k127_1445946_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000007536 140.0
HKD1_k127_1445946_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000003087 135.0
HKD1_k127_1445946_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000313 135.0
HKD1_k127_1445946_4 Protein of unknown function (DUF962) - - - 0.00000000000003707 78.0
HKD1_k127_1445946_5 peptidyl-tyrosine sulfation - - - 0.000000003819 68.0
HKD1_k127_1505004_0 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 329.0
HKD1_k127_1505004_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 308.0
HKD1_k127_1505004_2 DsrE/DsrF-like family - - - 0.000000000000000000000000007136 111.0
HKD1_k127_1505004_3 Protein of unknown function (DUF2911) - - - 0.000000000000003116 85.0
HKD1_k127_1505004_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000119 84.0
HKD1_k127_1514396_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 636.0
HKD1_k127_1514396_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000001411 181.0
HKD1_k127_1514396_2 Flavin reductase like domain - - - 0.000000000000000000000000000000002436 134.0
HKD1_k127_152060_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 404.0
HKD1_k127_152060_1 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000001449 245.0
HKD1_k127_152060_10 - - - - 0.00000000000006544 74.0
HKD1_k127_152060_11 - - - - 0.0000000003577 60.0
HKD1_k127_152060_12 extracellular matrix structural constituent - - - 0.0000001095 62.0
HKD1_k127_152060_2 - - - - 0.00000000000000000000000000000000000007045 156.0
HKD1_k127_152060_3 MarC family integral membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000007292 162.0
HKD1_k127_152060_4 - - - - 0.000000000000000000000000000000000006651 139.0
HKD1_k127_152060_5 - - - - 0.000000000000000000000000007291 110.0
HKD1_k127_152060_6 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000001698 126.0
HKD1_k127_152060_7 Phospholipid methyltransferase - - - 0.000000000000000000000001393 110.0
HKD1_k127_152060_8 - - - - 0.000000000000000000004151 94.0
HKD1_k127_152060_9 Alpha/beta hydrolase of unknown function (DUF1400) - - - 0.000000000000006529 87.0
HKD1_k127_1524746_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 538.0
HKD1_k127_1524746_1 2Fe-2S -binding domain protein K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000104 189.0
HKD1_k127_1541951_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.102e-253 797.0
HKD1_k127_1541951_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
HKD1_k127_1541951_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 355.0
HKD1_k127_1541951_3 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000191 179.0
HKD1_k127_1541951_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000006377 154.0
HKD1_k127_1541951_5 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000003617 140.0
HKD1_k127_1541951_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000001337 117.0
HKD1_k127_1541951_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000006954 104.0
HKD1_k127_1541951_8 SMART Tetratricopeptide - - - 0.000000000002938 79.0
HKD1_k127_1541951_9 Cache domain - - - 0.0000002783 61.0
HKD1_k127_1546331_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 583.0
HKD1_k127_1546331_1 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000004648 194.0
HKD1_k127_1546331_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000001196 170.0
HKD1_k127_1546331_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000008512 174.0
HKD1_k127_1546331_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000001807 156.0
HKD1_k127_1595901_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 386.0
HKD1_k127_1595901_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 308.0
HKD1_k127_1595901_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001385 181.0
HKD1_k127_1595901_3 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000000000000000004269 151.0
HKD1_k127_1595901_4 Fibronectin type III domain protein - - - 0.000000000000000000000005714 118.0
HKD1_k127_1595901_5 Protein of unknown function (DUF1573) - - - 0.0000000000000001459 95.0
HKD1_k127_1634198_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 344.0
HKD1_k127_1634198_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 323.0
HKD1_k127_1634198_10 PBS lyase HEAT-like repeat - - - 0.00000000001048 79.0
HKD1_k127_1634198_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000007364 268.0
HKD1_k127_1634198_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000001252 223.0
HKD1_k127_1634198_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000002065 201.0
HKD1_k127_1634198_5 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000004263 139.0
HKD1_k127_1634198_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000007569 133.0
HKD1_k127_1634198_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000001567 134.0
HKD1_k127_1634198_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000001293 127.0
HKD1_k127_1634198_9 PFAM Transglutaminase-like - - - 0.0000000000003275 80.0
HKD1_k127_1635675_0 gluconolactonase activity K14274,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001999 275.0
HKD1_k127_1635675_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000004471 51.0
HKD1_k127_1635675_2 Amino acid permease K03294 - - 0.0001603 46.0
HKD1_k127_16701_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1293.0
HKD1_k127_16701_1 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 355.0
HKD1_k127_16701_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006213 258.0
HKD1_k127_16701_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000004176 218.0
HKD1_k127_16701_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000002351 122.0
HKD1_k127_16701_5 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000001626 120.0
HKD1_k127_16701_6 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.000000000000000000000000001792 123.0
HKD1_k127_16701_7 lactate metabolic process - - - 0.0000000000000000000000001023 112.0
HKD1_k127_1685386_0 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000002487 163.0
HKD1_k127_1763031_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 537.0
HKD1_k127_1763031_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 435.0
HKD1_k127_1763031_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004769 275.0
HKD1_k127_1763031_3 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000003725 165.0
HKD1_k127_1763031_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000002473 144.0
HKD1_k127_1763031_5 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000002836 106.0
HKD1_k127_1763031_6 photosystem II stabilization - - - 0.0000000004932 72.0
HKD1_k127_1799479_0 Sortilin, neurotensin receptor 3, - - - 0.0 1127.0
HKD1_k127_1799479_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
HKD1_k127_1799479_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008475 272.0
HKD1_k127_1799479_3 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000004951 252.0
HKD1_k127_1799479_4 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000006176 156.0
HKD1_k127_180785_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 398.0
HKD1_k127_180785_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 356.0
HKD1_k127_180785_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000007141 217.0
HKD1_k127_180785_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000007835 209.0
HKD1_k127_180785_4 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000001648 147.0
HKD1_k127_180785_5 - - - - 0.00000000000000000000000000002035 125.0
HKD1_k127_1810456_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 608.0
HKD1_k127_1810456_1 COG0438 Glycosyltransferase K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 359.0
HKD1_k127_1810456_2 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 345.0
HKD1_k127_1810456_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 316.0
HKD1_k127_1810456_4 inorganic diphosphatase activity K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000001796 204.0
HKD1_k127_1810456_5 - - - - 0.000000006915 62.0
HKD1_k127_1831310_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000006902 242.0
HKD1_k127_1831310_1 Belongs to the UPF0102 family K07460 - - 0.00004046 47.0
HKD1_k127_1846962_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 351.0
HKD1_k127_1846962_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000938 128.0
HKD1_k127_1866232_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1027.0
HKD1_k127_1866232_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 486.0
HKD1_k127_188408_0 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 294.0
HKD1_k127_188408_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000001241 225.0
HKD1_k127_188408_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000001905 110.0
HKD1_k127_188408_3 glycosyl transferase K20444 - - 0.0000000000000000385 92.0
HKD1_k127_188408_4 TonB-dependent receptor K16092 - - 0.0000000000000003901 94.0
HKD1_k127_188408_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000009068 85.0
HKD1_k127_188408_6 Bacterial regulatory proteins, tetR family - - - 0.0000002904 60.0
HKD1_k127_188408_7 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000001946 62.0
HKD1_k127_1888618_0 Bacterial periplasmic substrate-binding proteins K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 539.0
HKD1_k127_1888618_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 323.0
HKD1_k127_1888618_2 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
HKD1_k127_1888618_3 - - - - 0.0000000000000000000000000000003833 136.0
HKD1_k127_1888618_5 cheY-homologous receiver domain - - - 0.0000000000000000002311 92.0
HKD1_k127_1889038_0 B12 binding domain - - - 7.999e-199 650.0
HKD1_k127_1889038_1 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 376.0
HKD1_k127_1889038_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000001795 192.0
HKD1_k127_1889038_3 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.0000000000000000000001078 115.0
HKD1_k127_1905828_0 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000001427 175.0
HKD1_k127_1905828_1 Transmembrane and TPR repeat-containing protein 1 - - - 0.0000000000000000000000000000000000000000253 174.0
HKD1_k127_191265_0 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 260.0
HKD1_k127_191265_1 PFAM Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000008532 162.0
HKD1_k127_191265_2 DinB family - - - 0.000000000000000000000000000008777 125.0
HKD1_k127_1923772_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.603e-221 731.0
HKD1_k127_1923772_1 Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 511.0
HKD1_k127_1923772_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000003362 113.0
HKD1_k127_1923772_3 Thioredoxin - - - 0.00000000000000000003035 103.0
HKD1_k127_1923772_4 peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000008467 93.0
HKD1_k127_1923772_5 PFAM Biotin lipoyl attachment - - - 0.000000000001925 80.0
HKD1_k127_1923772_6 Protein of unknown function (DUF507) K09804 - - 0.00008292 55.0
HKD1_k127_1925511_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 359.0
HKD1_k127_1925511_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 327.0
HKD1_k127_1925511_2 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
HKD1_k127_1925511_3 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001206 184.0
HKD1_k127_1925511_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000003994 147.0
HKD1_k127_1925511_5 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000004397 154.0
HKD1_k127_1946159_0 cellulose binding - - - 1.115e-300 943.0
HKD1_k127_1946159_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 329.0
HKD1_k127_1968065_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 564.0
HKD1_k127_1968065_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 532.0
HKD1_k127_1968065_2 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 441.0
HKD1_k127_1968065_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 355.0
HKD1_k127_1968065_4 - - - - 0.000000000000000000000000000000000000000000000002513 188.0
HKD1_k127_1968065_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 0.000000000000000000000000000000000008256 152.0
HKD1_k127_1968065_6 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000001867 145.0
HKD1_k127_199852_0 oligopeptide transporter, OPT family - - - 3.132e-220 702.0
HKD1_k127_199852_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 502.0
HKD1_k127_199852_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000003668 147.0
HKD1_k127_199852_3 SnoaL-like domain - - - 0.00000000000000000000009994 106.0
HKD1_k127_199852_4 Glutaredoxin K03676 - - 0.00000001004 57.0
HKD1_k127_199852_5 phosphodiesterase - - - 0.0003083 51.0
HKD1_k127_199852_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0004913 53.0
HKD1_k127_200880_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 629.0
HKD1_k127_200880_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003668 250.0
HKD1_k127_2012829_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.707e-266 831.0
HKD1_k127_2012829_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.994e-228 733.0
HKD1_k127_2012829_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 409.0
HKD1_k127_2012829_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 363.0
HKD1_k127_2012829_4 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001004 280.0
HKD1_k127_2012829_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000002988 236.0
HKD1_k127_2012829_6 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000001881 179.0
HKD1_k127_2012829_7 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000104 148.0
HKD1_k127_2012829_8 Phospholipid methyltransferase - - - 0.0000000000000000000005977 103.0
HKD1_k127_2012829_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000005106 77.0
HKD1_k127_2013260_0 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 454.0
HKD1_k127_2013260_1 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 408.0
HKD1_k127_2013260_10 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000001552 114.0
HKD1_k127_2013260_11 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000777 112.0
HKD1_k127_2013260_12 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000009866 113.0
HKD1_k127_2013260_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000175 107.0
HKD1_k127_2013260_14 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000006264 91.0
HKD1_k127_2013260_15 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000007486 61.0
HKD1_k127_2013260_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 354.0
HKD1_k127_2013260_3 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 341.0
HKD1_k127_2013260_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000004926 250.0
HKD1_k127_2013260_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005514 259.0
HKD1_k127_2013260_6 MBOAT, membrane-bound O-acyltransferase family K03739,K19294 - - 0.0000000000000000000000000000000000000000000000000007204 199.0
HKD1_k127_2013260_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000001099 154.0
HKD1_k127_2013260_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000464 136.0
HKD1_k127_2013260_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000003618 123.0
HKD1_k127_2017526_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 506.0
HKD1_k127_2017526_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 451.0
HKD1_k127_2017526_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000002413 234.0
HKD1_k127_2017526_3 peptidyl-tyrosine sulfation - - - 0.0000002755 59.0
HKD1_k127_2017526_5 Cna B domain protein - - - 0.00005083 56.0
HKD1_k127_2032191_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 558.0
HKD1_k127_2032191_1 ABC transporter, transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 576.0
HKD1_k127_2032191_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
HKD1_k127_2032191_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000137 137.0
HKD1_k127_2032191_12 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000003463 143.0
HKD1_k127_2032191_13 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000003969 96.0
HKD1_k127_2032191_14 Bacterial PH domain - - - 0.00000000000002602 87.0
HKD1_k127_2032191_15 Heavy-metal resistance - - - 0.00000000000004046 80.0
HKD1_k127_2032191_16 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.000000000001509 80.0
HKD1_k127_2032191_17 Domain of unknown function (DUF4440) - - - 0.000000000002722 73.0
HKD1_k127_2032191_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 540.0
HKD1_k127_2032191_3 Major facilitator Superfamily K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 482.0
HKD1_k127_2032191_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 375.0
HKD1_k127_2032191_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 347.0
HKD1_k127_2032191_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 341.0
HKD1_k127_2032191_7 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002342 263.0
HKD1_k127_2032191_8 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 260.0
HKD1_k127_2032191_9 Abc transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000003434 248.0
HKD1_k127_204837_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006107 269.0
HKD1_k127_204837_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002111 238.0
HKD1_k127_204837_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003687 250.0
HKD1_k127_204837_3 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000004274 248.0
HKD1_k127_2050488_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 405.0
HKD1_k127_2050488_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 309.0
HKD1_k127_2050488_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 295.0
HKD1_k127_2066778_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 509.0
HKD1_k127_2066778_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 314.0
HKD1_k127_2066778_2 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000006734 211.0
HKD1_k127_2066778_4 ABC-2 family transporter protein K01992 - - 0.00000000013 63.0
HKD1_k127_2068556_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 608.0
HKD1_k127_2068556_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 477.0
HKD1_k127_2068556_10 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000003034 244.0
HKD1_k127_2068556_11 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000000000000000000000001922 175.0
HKD1_k127_2068556_12 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000001561 139.0
HKD1_k127_2068556_13 - - - - 0.00000000000000000000000000000000569 148.0
HKD1_k127_2068556_14 Predicted membrane protein (DUF2157) - - - 0.0000000000000001602 88.0
HKD1_k127_2068556_15 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000006116 76.0
HKD1_k127_2068556_16 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00003915 57.0
HKD1_k127_2068556_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 470.0
HKD1_k127_2068556_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
HKD1_k127_2068556_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 385.0
HKD1_k127_2068556_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 325.0
HKD1_k127_2068556_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000001866 286.0
HKD1_k127_2068556_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000003778 254.0
HKD1_k127_2068556_8 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000002337 262.0
HKD1_k127_2068556_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000007932 244.0
HKD1_k127_2073685_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.373e-255 797.0
HKD1_k127_2073685_1 Membrane - - - 0.000000488 63.0
HKD1_k127_2073685_2 - - - - 0.00001622 51.0
HKD1_k127_2073685_3 SnoaL-like domain - - - 0.0002009 53.0
HKD1_k127_207545_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 424.0
HKD1_k127_207545_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 383.0
HKD1_k127_207545_10 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000006039 121.0
HKD1_k127_207545_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000001463 118.0
HKD1_k127_207545_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 348.0
HKD1_k127_207545_3 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 331.0
HKD1_k127_207545_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009658 300.0
HKD1_k127_207545_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001285 285.0
HKD1_k127_207545_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003734 285.0
HKD1_k127_207545_7 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000001203 179.0
HKD1_k127_207545_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000009359 166.0
HKD1_k127_207545_9 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000009375 139.0
HKD1_k127_2082491_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 542.0
HKD1_k127_2082491_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004106 252.0
HKD1_k127_2082491_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000005933 213.0
HKD1_k127_2082491_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000134 140.0
HKD1_k127_2082491_4 Leucine rich repeats (6 copies) - - - 0.00000002339 65.0
HKD1_k127_2082491_5 DNA-sulfur modification-associated - - - 0.0000045 59.0
HKD1_k127_2083840_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 413.0
HKD1_k127_2083840_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000002128 183.0
HKD1_k127_2083840_2 DinB family - - - 0.00000001172 63.0
HKD1_k127_2083840_3 Lactoylglutathione lyase and related lyases - - - 0.0000001179 53.0
HKD1_k127_2087906_0 Heat shock 70 kDa protein K04043 - - 3.71e-299 929.0
HKD1_k127_2087906_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 604.0
HKD1_k127_2087906_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000001681 175.0
HKD1_k127_2087906_11 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000007022 140.0
HKD1_k127_2087906_12 Peptidase, M23 K21471 - - 0.0000000000000000000000000000005155 143.0
HKD1_k127_2087906_13 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000001572 128.0
HKD1_k127_2087906_14 Transglutaminase/protease-like homologues - - - 0.0000000000000000000001208 116.0
HKD1_k127_2087906_15 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000002699 93.0
HKD1_k127_2087906_16 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000008057 71.0
HKD1_k127_2087906_17 Domain of unknown function (DUF1844) - - - 0.000000001761 67.0
HKD1_k127_2087906_18 Domain of unknown function (DUF4388) - - - 0.00002792 57.0
HKD1_k127_2087906_19 oxidoreductase activity - - - 0.0002626 55.0
HKD1_k127_2087906_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
HKD1_k127_2087906_20 Tetratricopeptide repeat - - - 0.0007699 52.0
HKD1_k127_2087906_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 318.0
HKD1_k127_2087906_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000002156 230.0
HKD1_k127_2087906_5 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000002989 223.0
HKD1_k127_2087906_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000006808 223.0
HKD1_k127_2087906_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000003526 197.0
HKD1_k127_2087906_8 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000006435 186.0
HKD1_k127_2087906_9 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000004749 170.0
HKD1_k127_2094900_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 7.888e-256 812.0
HKD1_k127_2094900_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.251e-203 643.0
HKD1_k127_2094900_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000009884 101.0
HKD1_k127_2094900_11 Family of unknown function (DUF5335) - - - 0.0001334 52.0
HKD1_k127_2094900_2 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 522.0
HKD1_k127_2094900_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 334.0
HKD1_k127_2094900_4 Rnd family efflux transporter mfp subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 299.0
HKD1_k127_2094900_5 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000008288 245.0
HKD1_k127_2094900_6 Erythromycin esterase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000828 243.0
HKD1_k127_2094900_7 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000004915 244.0
HKD1_k127_2094900_8 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000002149 186.0
HKD1_k127_2094900_9 CBS domain - - - 0.0000000000000000006868 93.0
HKD1_k127_20956_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.883e-224 712.0
HKD1_k127_209625_0 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
HKD1_k127_209625_1 Neprosin activation peptide - - - 0.000000000000000000000000000000000000000000000000000000009461 226.0
HKD1_k127_209625_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000004278 169.0
HKD1_k127_209625_3 - - - - 0.00000000001712 65.0
HKD1_k127_2097337_0 Putative glucoamylase K13688 - - 2.987e-224 711.0
HKD1_k127_2097337_1 - - - - 0.00000000000000000000136 107.0
HKD1_k127_210499_0 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 499.0
HKD1_k127_210499_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002883 285.0
HKD1_k127_210499_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001608 217.0
HKD1_k127_210499_3 - - - - 0.000000000000000000000000000000000000000000000000000000008435 226.0
HKD1_k127_210499_4 Chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000009665 214.0
HKD1_k127_210499_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000003155 163.0
HKD1_k127_210499_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000006601 84.0
HKD1_k127_2114144_0 Belongs to the aldehyde dehydrogenase family K00128,K00131 - 1.2.1.3,1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 378.0
HKD1_k127_2114144_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000003467 74.0
HKD1_k127_2126447_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.248e-233 730.0
HKD1_k127_2126447_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.875e-231 725.0
HKD1_k127_2126447_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 271.0
HKD1_k127_2126447_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000001839 121.0
HKD1_k127_2126447_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000008993 74.0
HKD1_k127_2126447_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000006433 61.0
HKD1_k127_2126447_6 Elongation factor SelB, winged helix K03833 - - 0.0000017 50.0
HKD1_k127_2126447_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00008761 51.0
HKD1_k127_2144418_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007856 288.0
HKD1_k127_2144418_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000004655 265.0
HKD1_k127_2144418_2 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000002037 209.0
HKD1_k127_2144418_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000001964 144.0
HKD1_k127_2144418_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000002287 80.0
HKD1_k127_2144418_5 histone H2A K63-linked ubiquitination - - - 0.0000000000000008665 91.0
HKD1_k127_2144418_6 Peptidase M56 - - - 0.000000000000005153 90.0
HKD1_k127_2148734_0 cellulose binding - - - 7.23e-226 737.0
HKD1_k127_2148734_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000003425 211.0
HKD1_k127_2148734_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000001681 194.0
HKD1_k127_2148734_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000002554 172.0
HKD1_k127_2148734_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000001033 123.0
HKD1_k127_2150797_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.142e-247 805.0
HKD1_k127_2150797_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 424.0
HKD1_k127_2150797_2 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000006134 110.0
HKD1_k127_2150797_3 methyltransferase activity - - - 0.000000000000000000006025 106.0
HKD1_k127_2150797_4 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000136 84.0
HKD1_k127_2150797_5 - - - - 0.0000000000000001807 91.0
HKD1_k127_2150797_6 - - - - 0.00000000000001598 82.0
HKD1_k127_2150797_7 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000001185 79.0
HKD1_k127_2150797_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000658 73.0
HKD1_k127_2153931_1 Putative porin - - - 0.00000001684 66.0
HKD1_k127_2153931_2 Outer membrane lipoprotein-sorting protein - - - 0.0002362 49.0
HKD1_k127_2156559_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 522.0
HKD1_k127_2156559_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 514.0
HKD1_k127_2156559_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 299.0
HKD1_k127_2156559_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 321.0
HKD1_k127_2156559_4 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 311.0
HKD1_k127_2156559_5 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000002333 184.0
HKD1_k127_2156559_6 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000007438 160.0
HKD1_k127_2157058_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 486.0
HKD1_k127_2157058_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000003383 267.0
HKD1_k127_2157058_2 proline racemase K01777 - 5.1.1.4 0.00000000000003337 86.0
HKD1_k127_2161908_0 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 8.623e-242 772.0
HKD1_k127_2161908_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 566.0
HKD1_k127_2161908_10 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000009139 142.0
HKD1_k127_2161908_11 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000008773 125.0
HKD1_k127_2161908_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000003751 126.0
HKD1_k127_2161908_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000009655 117.0
HKD1_k127_2161908_14 SNARE associated Golgi protein - - - 0.00000000001621 74.0
HKD1_k127_2161908_15 protein conserved in bacteria K09931 - - 0.00000001803 64.0
HKD1_k127_2161908_2 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 411.0
HKD1_k127_2161908_3 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 329.0
HKD1_k127_2161908_4 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 347.0
HKD1_k127_2161908_5 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006828 295.0
HKD1_k127_2161908_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000002137 267.0
HKD1_k127_2161908_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000005333 222.0
HKD1_k127_2161908_8 Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000003095 175.0
HKD1_k127_2161908_9 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001365 143.0
HKD1_k127_2164024_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005228 274.0
HKD1_k127_2164024_1 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000000007654 113.0
HKD1_k127_2195081_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
HKD1_k127_2195081_1 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000001004 219.0
HKD1_k127_2195081_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000006178 85.0
HKD1_k127_2207723_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 350.0
HKD1_k127_2207723_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 321.0
HKD1_k127_2207723_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001362 301.0
HKD1_k127_2207723_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
HKD1_k127_2207723_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000002041 270.0
HKD1_k127_2207723_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000001605 164.0
HKD1_k127_2207723_6 oxidoreductase activity - - - 0.0000000000000000000000000000006249 141.0
HKD1_k127_2207723_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000002411 116.0
HKD1_k127_2207723_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002012 115.0
HKD1_k127_2209776_0 ABC transporter, transmembrane K11085 - - 4.356e-253 797.0
HKD1_k127_2209776_1 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000001461 138.0
HKD1_k127_2209776_2 SnoaL-like domain - - - 0.00000000000000000068 95.0
HKD1_k127_2216133_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002337 282.0
HKD1_k127_2216133_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000004272 161.0
HKD1_k127_2216133_2 KR domain K07535 - - 0.000000000000000000000000000000000004019 142.0
HKD1_k127_2243264_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 452.0
HKD1_k127_2243264_1 Tetratricopeptide repeat - - - 0.000000000000004669 83.0
HKD1_k127_2248898_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000003587 226.0
HKD1_k127_2252446_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 608.0
HKD1_k127_2255869_0 Glycosyl hydrolase family 47 K01230,K10085 - 3.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 496.0
HKD1_k127_2255869_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
HKD1_k127_2255869_10 Putative bacterial lipoprotein (DUF799) - - - 0.0000000000000000000007192 112.0
HKD1_k127_2255869_11 - - - - 0.00000000000003759 86.0
HKD1_k127_2255869_12 - - - - 0.000000000008151 79.0
HKD1_k127_2255869_13 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0000000000158 78.0
HKD1_k127_2255869_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 368.0
HKD1_k127_2255869_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006206 301.0
HKD1_k127_2255869_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001117 239.0
HKD1_k127_2255869_5 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
HKD1_k127_2255869_6 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000000001183 175.0
HKD1_k127_2255869_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000003228 154.0
HKD1_k127_2255869_8 amine dehydrogenase activity - - - 0.00000000000000000000000006955 113.0
HKD1_k127_2255869_9 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.000000000000000000000001302 121.0
HKD1_k127_2262005_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 360.0
HKD1_k127_2262005_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000009861 251.0
HKD1_k127_2262005_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000008047 164.0
HKD1_k127_2262005_3 YqeY-like protein K09117 - - 0.000000000000000000000000000000004873 132.0
HKD1_k127_2262005_4 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000004897 128.0
HKD1_k127_2262005_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000002432 131.0
HKD1_k127_2262005_6 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000008483 74.0
HKD1_k127_2262005_7 Deoxynucleoside kinase - - - 0.0001603 46.0
HKD1_k127_2262005_8 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.0001903 51.0
HKD1_k127_2273846_0 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000001748 144.0
HKD1_k127_2273846_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000002689 128.0
HKD1_k127_2273846_2 - - - - 0.000000000000000000000000000002703 125.0
HKD1_k127_2273846_3 RNA recognition motif - - - 0.00000000000000000006103 93.0
HKD1_k127_2273846_4 - - - - 0.0000000004883 70.0
HKD1_k127_2289080_0 PFAM ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 316.0
HKD1_k127_2289080_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003241 281.0
HKD1_k127_2289080_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001726 272.0
HKD1_k127_2289080_3 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.000000000000000000000000000000000000000000000000000000001589 229.0
HKD1_k127_2289080_4 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000006451 206.0
HKD1_k127_2289080_5 - - - - 0.0000000000000000000000000000000000000000000007805 190.0
HKD1_k127_2289080_6 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000518 172.0
HKD1_k127_2289080_7 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000003091 160.0
HKD1_k127_2307766_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.098e-291 918.0
HKD1_k127_2307766_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 549.0
HKD1_k127_2307766_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 403.0
HKD1_k127_2307766_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
HKD1_k127_2307766_4 - - - - 0.00000000000000522 78.0
HKD1_k127_2307766_5 - - - - 0.0007606 53.0
HKD1_k127_2332020_0 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 477.0
HKD1_k127_2332020_1 DNA-binding transcription factor activity - - - 0.00000000000000000000000001799 112.0
HKD1_k127_2332020_2 glyoxalase III activity - - - 0.00000009774 59.0
HKD1_k127_2332020_3 - - - - 0.000000101 59.0
HKD1_k127_2348148_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 469.0
HKD1_k127_2348148_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 379.0
HKD1_k127_2348148_2 - - - - 0.0000000000000000000000000000000000000000000000005264 183.0
HKD1_k127_2348148_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000002011 156.0
HKD1_k127_2348148_4 - - - - 0.0000000000000000000000000000002241 126.0
HKD1_k127_2348148_5 methylamine metabolic process K15977 - - 0.00000000000000000000000004498 115.0
HKD1_k127_2348148_6 Family of unknown function (DUF5335) - - - 0.000000004491 63.0
HKD1_k127_2348148_7 Belongs to the peptidase S8 family - - - 0.0001029 56.0
HKD1_k127_2353260_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 458.0
HKD1_k127_2353260_1 Cysteine-rich CPXCG - - - 0.00000000000003759 74.0
HKD1_k127_2353260_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K20444 - - 0.0000004275 60.0
HKD1_k127_2360349_0 Belongs to the peptidase M16 family K07263 - - 0.0 1052.0
HKD1_k127_2360349_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.056e-277 878.0
HKD1_k127_2360349_10 Lipocalin-like domain - - - 0.00000000000000000000000000000961 123.0
HKD1_k127_2360349_11 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000001389 99.0
HKD1_k127_2360349_13 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000003155 83.0
HKD1_k127_2360349_14 - - - - 0.00000000000005946 79.0
HKD1_k127_2360349_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 528.0
HKD1_k127_2360349_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 373.0
HKD1_k127_2360349_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 332.0
HKD1_k127_2360349_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
HKD1_k127_2360349_6 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001693 254.0
HKD1_k127_2360349_7 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008383 251.0
HKD1_k127_2360349_8 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000001003 200.0
HKD1_k127_2360349_9 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000003211 141.0
HKD1_k127_2375847_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 377.0
HKD1_k127_2375847_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000156 150.0
HKD1_k127_2382551_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000005688 207.0
HKD1_k127_2382551_1 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.0000000000000000000000000001983 119.0
HKD1_k127_2382551_2 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000005113 88.0
HKD1_k127_2382551_3 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000004451 78.0
HKD1_k127_2388074_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 623.0
HKD1_k127_2388074_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 535.0
HKD1_k127_2388074_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 525.0
HKD1_k127_2388074_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 497.0
HKD1_k127_2388074_4 Peptidase S10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 477.0
HKD1_k127_2388346_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 565.0
HKD1_k127_2388346_1 Cation efflux family K14696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 293.0
HKD1_k127_2388346_2 - - - - 0.00000000000000000006373 99.0
HKD1_k127_2388346_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000002992 70.0
HKD1_k127_2390265_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000001855 282.0
HKD1_k127_2390265_1 Glycosyl transferase 4-like domain K03208 - - 0.0000000000000000000000000000000000003011 147.0
HKD1_k127_2390265_2 extracellular polysaccharide biosynthetic process K07011 - - 0.0000002579 64.0
HKD1_k127_2391727_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 473.0
HKD1_k127_2391727_1 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
HKD1_k127_2391727_2 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000000000000000000005399 118.0
HKD1_k127_2393060_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 401.0
HKD1_k127_2393060_1 M3B, thimet oligopeptidase F K01392 - 3.4.24.15 0.0000000000000000000000004706 110.0
HKD1_k127_2400994_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
HKD1_k127_2400994_1 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000005302 126.0
HKD1_k127_2400994_2 - - - - 0.000000000000000007556 94.0
HKD1_k127_2410407_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000007594 198.0
HKD1_k127_2456769_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 270.0
HKD1_k127_2456769_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000006944 188.0
HKD1_k127_2456769_2 Protein of unknown function (DUF983) - - - 0.0000000009158 64.0
HKD1_k127_2456769_3 chlorophyll binding - - - 0.00000009118 64.0
HKD1_k127_2456769_4 doubled CXXCH - - - 0.0001232 55.0
HKD1_k127_2462290_0 - - - - 0.000000000000000000000000000000000000000001037 174.0
HKD1_k127_2470779_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 302.0
HKD1_k127_2470779_1 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004706 242.0
HKD1_k127_2470779_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000001486 250.0
HKD1_k127_2470779_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000002117 199.0
HKD1_k127_2470779_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000001271 156.0
HKD1_k127_2470779_5 Domain of unknown function (DUF4340) - - - 0.00000000001342 79.0
HKD1_k127_2470779_6 - - - - 0.00000000006074 72.0
HKD1_k127_2470779_7 - - - - 0.0000001967 63.0
HKD1_k127_247774_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1223.0
HKD1_k127_247774_2 Iron-sulphur cluster biosynthesis K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564 - 0.0002787 48.0
HKD1_k127_2485648_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000003219 173.0
HKD1_k127_2485648_1 Transcriptional regulator K07979 - - 0.00000000000000041 83.0
HKD1_k127_2486989_0 Amino acid permease - - - 8.664e-208 666.0
HKD1_k127_2486989_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000009072 224.0
HKD1_k127_2495177_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 3.881e-204 644.0
HKD1_k127_2495177_1 PFAM cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 606.0
HKD1_k127_2495177_2 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 483.0
HKD1_k127_2495177_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 439.0
HKD1_k127_2495177_4 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 324.0
HKD1_k127_2495177_5 helix_turn_helix, Lux Regulon K07684 - - 0.00000000001635 70.0
HKD1_k127_2495177_6 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000005028 66.0
HKD1_k127_2507937_0 Sortilin, neurotensin receptor 3, - - - 0.0 1220.0
HKD1_k127_2507937_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000002244 197.0
HKD1_k127_2507937_2 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000000000000000001172 153.0
HKD1_k127_2507937_3 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 0.0000000000000000000981 89.0
HKD1_k127_2507937_4 photosynthesis - - - 0.000000001796 62.0
HKD1_k127_2509086_0 Involved in the tonB-independent uptake of proteins - - - 1.013e-227 737.0
HKD1_k127_2509086_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 506.0
HKD1_k127_2509086_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000004472 77.0
HKD1_k127_2509086_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000001335 53.0
HKD1_k127_2525363_0 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
HKD1_k127_2525363_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002112 283.0
HKD1_k127_2525363_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000002534 103.0
HKD1_k127_2531883_0 - - - - 0.0000000000000000000000000000000000213 139.0
HKD1_k127_2531883_1 Bacterial membrane protein YfhO - - - 0.0000000000000000000000001724 124.0
HKD1_k127_2531883_2 Methyltransferase domain - - - 0.000000000000000000002122 108.0
HKD1_k127_2531883_3 Bacterial membrane protein, YfhO - - - 0.0001271 55.0
HKD1_k127_2539452_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000003911 194.0
HKD1_k127_2539452_1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.0000000000002228 70.0
HKD1_k127_2540883_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 475.0
HKD1_k127_2540883_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
HKD1_k127_2540883_10 Phosphoribosyl transferase domain - - - 0.0000000000000000000000005084 117.0
HKD1_k127_2540883_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 426.0
HKD1_k127_2540883_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 381.0
HKD1_k127_2540883_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 323.0
HKD1_k127_2540883_5 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003656 286.0
HKD1_k127_2540883_6 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008209 274.0
HKD1_k127_2540883_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000002098 208.0
HKD1_k127_2540883_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000236 128.0
HKD1_k127_2540883_9 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000002219 118.0
HKD1_k127_2576488_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 365.0
HKD1_k127_2576488_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
HKD1_k127_2576488_2 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 358.0
HKD1_k127_2576488_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000259 214.0
HKD1_k127_2576488_4 Proline racemase K12658 - 5.1.1.8 0.00000000000000000000000000000000000007302 145.0
HKD1_k127_2576488_5 peptidase M24 K01271 - 3.4.13.9 0.000000000000000001644 86.0
HKD1_k127_2576488_6 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000007179 89.0
HKD1_k127_258168_0 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000008321 238.0
HKD1_k127_258168_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000002659 108.0
HKD1_k127_258168_2 cheY-homologous receiver domain - - - 0.00000000000000000009109 93.0
HKD1_k127_258168_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000001925 58.0
HKD1_k127_2625156_0 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 461.0
HKD1_k127_2625156_1 Pyridoxal-dependent decarboxylase conserved domain K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 351.0
HKD1_k127_2625156_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000187 261.0
HKD1_k127_2625156_3 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000249 216.0
HKD1_k127_2625156_4 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000174 149.0
HKD1_k127_2625156_5 Protein of unknown function (DUF1569) - - - 0.00000000000000000000000005123 118.0
HKD1_k127_2625156_6 SnoaL-like domain - - - 0.0000000000000000000000004053 110.0
HKD1_k127_2625156_7 Heavy-metal resistance - - - 0.0007678 48.0
HKD1_k127_2626694_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 361.0
HKD1_k127_2626694_1 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 357.0
HKD1_k127_2626694_10 Psort location CytoplasmicMembrane, score - - - 0.00000005327 67.0
HKD1_k127_2626694_2 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001534 261.0
HKD1_k127_2626694_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000004748 214.0
HKD1_k127_2626694_4 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000000000000000001153 190.0
HKD1_k127_2626694_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000002421 117.0
HKD1_k127_2626694_6 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000008169 117.0
HKD1_k127_2626694_7 Bacterial membrane protein YfhO - - - 0.0000000000000000009166 102.0
HKD1_k127_2626694_8 Bacterial membrane protein, YfhO - - - 0.00000000000000005152 96.0
HKD1_k127_2626694_9 - - - - 0.0000000000005085 82.0
HKD1_k127_2630662_0 PFAM Prolyl oligopeptidase family K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 369.0
HKD1_k127_2630662_1 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
HKD1_k127_2630662_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000009689 154.0
HKD1_k127_2631229_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 486.0
HKD1_k127_2631229_1 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 318.0
HKD1_k127_2631229_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000001506 145.0
HKD1_k127_2636056_0 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000003823 222.0
HKD1_k127_2636056_1 ASPIC and UnbV - - - 0.00000000000000009952 87.0
HKD1_k127_2636666_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 595.0
HKD1_k127_2636666_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 423.0
HKD1_k127_2637725_0 Protein kinase domain K12132 - 2.7.11.1 5.216e-212 688.0
HKD1_k127_2637725_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 333.0
HKD1_k127_2637725_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000008111 53.0
HKD1_k127_264541_0 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 407.0
HKD1_k127_264541_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 352.0
HKD1_k127_264541_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0009364 50.0
HKD1_k127_2648267_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 344.0
HKD1_k127_2648267_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 320.0
HKD1_k127_2732_0 COG0467 RecA-superfamily ATPases implicated in signal K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 506.0
HKD1_k127_2732_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 408.0
HKD1_k127_2732_10 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000003298 143.0
HKD1_k127_2732_11 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000001199 150.0
HKD1_k127_2732_12 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000008477 153.0
HKD1_k127_2732_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000002318 115.0
HKD1_k127_2732_14 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000005681 111.0
HKD1_k127_2732_16 Methylamine utilisation protein MauE - - - 0.000000000000000422 93.0
HKD1_k127_2732_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000001443 86.0
HKD1_k127_2732_18 - - - - 0.00000000000002943 83.0
HKD1_k127_2732_19 secretion protein K01993 - - 0.0000000000006127 81.0
HKD1_k127_2732_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 320.0
HKD1_k127_2732_20 Bacterial regulatory proteins, tetR family - - - 0.000002243 57.0
HKD1_k127_2732_21 Cytochrome c K00406 - - 0.00001955 52.0
HKD1_k127_2732_22 PFAM Outer membrane efflux protein - - - 0.0002168 53.0
HKD1_k127_2732_3 PFAM Iron permease FTR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 274.0
HKD1_k127_2732_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000002147 268.0
HKD1_k127_2732_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001628 259.0
HKD1_k127_2732_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000004786 260.0
HKD1_k127_2732_7 transporter (permease K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000007647 235.0
HKD1_k127_2732_8 DinB family - - - 0.0000000000000000000000000000000000000000001127 166.0
HKD1_k127_2732_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000616 154.0
HKD1_k127_2747554_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
HKD1_k127_2747554_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 282.0
HKD1_k127_2800280_0 Sortilin, neurotensin receptor 3, - - - 3.657e-272 876.0
HKD1_k127_2800280_1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01593 - 4.1.1.105,4.1.1.28 5.23e-210 661.0
HKD1_k127_2800280_2 - - - - 0.00000000000000000001405 94.0
HKD1_k127_289352_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 1.849e-302 970.0
HKD1_k127_289352_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.944e-279 928.0
HKD1_k127_289352_10 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000008144 188.0
HKD1_k127_289352_11 SMART CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000003293 168.0
HKD1_k127_289352_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000001141 166.0
HKD1_k127_289352_13 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000005455 156.0
HKD1_k127_289352_14 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000005946 125.0
HKD1_k127_289352_15 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000004051 125.0
HKD1_k127_289352_16 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000008591 124.0
HKD1_k127_289352_17 NMT1-like family K02051 - - 0.0000000000000005191 93.0
HKD1_k127_289352_18 Late embryogenesis abundant protein - - - 0.0000000000001472 85.0
HKD1_k127_289352_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.095e-211 672.0
HKD1_k127_289352_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 624.0
HKD1_k127_289352_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 551.0
HKD1_k127_289352_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 384.0
HKD1_k127_289352_6 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 382.0
HKD1_k127_289352_7 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007643 293.0
HKD1_k127_289352_8 Carboxyl transferase domain K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001715 250.0
HKD1_k127_289352_9 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000004595 241.0
HKD1_k127_294311_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000682 253.0
HKD1_k127_294311_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000653 184.0
HKD1_k127_294311_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000001345 84.0
HKD1_k127_294311_3 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000002643 64.0
HKD1_k127_296894_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002997 255.0
HKD1_k127_3013557_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1884.0
HKD1_k127_3013557_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.057e-305 949.0
HKD1_k127_3013557_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00001587 49.0
HKD1_k127_3013557_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 321.0
HKD1_k127_3013557_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000143 233.0
HKD1_k127_3013557_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000009824 213.0
HKD1_k127_3013557_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000001571 149.0
HKD1_k127_3013557_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000001873 121.0
HKD1_k127_3013557_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007088 79.0
HKD1_k127_3013557_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000006719 79.0
HKD1_k127_3019069_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.497e-196 621.0
HKD1_k127_3019069_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 563.0
HKD1_k127_3019069_10 - - - - 0.00000000000000000000000000000000000000000000002449 186.0
HKD1_k127_3019069_11 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000004464 168.0
HKD1_k127_3019069_12 - - - - 0.0000000000000000000000000000000000000000001594 181.0
HKD1_k127_3019069_13 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000009883 156.0
HKD1_k127_3019069_14 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000001604 156.0
HKD1_k127_3019069_15 DinB family - - - 0.00000000000000000000000000000186 129.0
HKD1_k127_3019069_16 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000001939 119.0
HKD1_k127_3019069_17 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000005485 115.0
HKD1_k127_3019069_19 COG0517 FOG CBS domain - - - 0.00000000000000000002665 98.0
HKD1_k127_3019069_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 554.0
HKD1_k127_3019069_20 - - - - 0.00000000000000002526 82.0
HKD1_k127_3019069_21 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000002993 89.0
HKD1_k127_3019069_22 Stress-responsive transcriptional regulator - - - 0.0000000000003046 83.0
HKD1_k127_3019069_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 444.0
HKD1_k127_3019069_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 435.0
HKD1_k127_3019069_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 359.0
HKD1_k127_3019069_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 368.0
HKD1_k127_3019069_7 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HKD1_k127_3019069_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002501 285.0
HKD1_k127_3019069_9 COG2931 RTX toxins and related Ca2 -binding - - - 0.00000000000000000000000000000000000000000000000621 198.0
HKD1_k127_3026906_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 324.0
HKD1_k127_3026906_1 VIT family - - - 0.000000000000000000000000004716 118.0
HKD1_k127_3026906_2 Sulfurtransferase - - - 0.000000000000000000008616 96.0
HKD1_k127_3026906_3 - - - - 0.000000004029 64.0
HKD1_k127_3040608_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005611 273.0
HKD1_k127_3040608_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000004531 238.0
HKD1_k127_3040608_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000002835 164.0
HKD1_k127_3040608_3 - - - - 0.00000000000000000003944 102.0
HKD1_k127_3040608_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000005384 49.0
HKD1_k127_3053548_0 Involved in the tonB-independent uptake of proteins - - - 2.896e-202 658.0
HKD1_k127_3053548_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 294.0
HKD1_k127_3056445_0 Putative glucoamylase K13688 - - 0.0 1855.0
HKD1_k127_3056445_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 386.0
HKD1_k127_3058397_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 520.0
HKD1_k127_3058397_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 490.0
HKD1_k127_3058397_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 422.0
HKD1_k127_3058397_3 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009003 254.0
HKD1_k127_3058397_4 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000004211 106.0
HKD1_k127_3058397_5 - - - - 0.0000004459 59.0
HKD1_k127_3061514_0 Belongs to the ClpA ClpB family K03696 - - 7.451e-285 899.0
HKD1_k127_3061514_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 572.0
HKD1_k127_3061514_10 COGs COG3603 conserved K09707 - - 0.000000000000000000000000000007045 130.0
HKD1_k127_3061514_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000001208 96.0
HKD1_k127_3061514_13 unfolded protein binding K06142 GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 - 0.00009984 53.0
HKD1_k127_3061514_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0002695 50.0
HKD1_k127_3061514_2 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 316.0
HKD1_k127_3061514_3 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 283.0
HKD1_k127_3061514_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000261 228.0
HKD1_k127_3061514_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001586 192.0
HKD1_k127_3061514_6 - - - - 0.0000000000000000000000000000000000000000000005682 177.0
HKD1_k127_3061514_7 DinB family - - - 0.0000000000000000000000000000000000000000003009 169.0
HKD1_k127_3061514_9 Haem-binding domain - - - 0.000000000000000000000000000000682 130.0
HKD1_k127_308464_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000003681 210.0
HKD1_k127_308464_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000008809 83.0
HKD1_k127_308464_3 Preprotein translocase SecG subunit K03075 - - 0.000000000000000994 83.0
HKD1_k127_3086114_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 582.0
HKD1_k127_3086114_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000005302 132.0
HKD1_k127_3087062_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 607.0
HKD1_k127_3087062_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 406.0
HKD1_k127_3087062_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 377.0
HKD1_k127_3087062_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 373.0
HKD1_k127_3087062_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000461 245.0
HKD1_k127_3087062_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000003436 238.0
HKD1_k127_3087062_6 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000196 223.0
HKD1_k127_3087062_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000004552 217.0
HKD1_k127_3087062_8 response regulator - - - 0.00000000000000000000003336 117.0
HKD1_k127_3087062_9 PFAM YbbR family protein - - - 0.00000000000000000001001 108.0
HKD1_k127_3088557_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000002836 202.0
HKD1_k127_3088557_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000009827 169.0
HKD1_k127_3098967_0 Sortilin, neurotensin receptor 3, - - - 7.375e-308 987.0
HKD1_k127_3098967_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000002962 182.0
HKD1_k127_3098967_2 cheY-homologous receiver domain - - - 0.000000000000000000000000846 112.0
HKD1_k127_3100515_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 376.0
HKD1_k127_3100515_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001072 288.0
HKD1_k127_3100515_2 - - - - 0.0000000000000000000000000000000006372 134.0
HKD1_k127_3100515_3 phosphorelay signal transduction system - - - 0.00000000000006077 81.0
HKD1_k127_3100515_4 cheY-homologous receiver domain K07657 - - 0.00000000000009072 82.0
HKD1_k127_3100515_5 PFAM Hpt domain protein - - - 0.000001171 62.0
HKD1_k127_3101643_0 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 410.0
HKD1_k127_3101643_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000005542 213.0
HKD1_k127_3101643_2 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000781 211.0
HKD1_k127_3101643_3 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000001345 159.0
HKD1_k127_3101643_4 PFAM Uncharacterised protein family UPF0029, Impact, N-terminal - - - 0.000000000000000002655 99.0
HKD1_k127_3121005_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 537.0
HKD1_k127_3121005_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 462.0
HKD1_k127_3121005_10 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000003767 171.0
HKD1_k127_3121005_11 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000004507 152.0
HKD1_k127_3121005_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 370.0
HKD1_k127_3121005_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 313.0
HKD1_k127_3121005_4 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
HKD1_k127_3121005_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000001797 263.0
HKD1_k127_3121005_6 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HKD1_k127_3121005_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000001299 222.0
HKD1_k127_3121005_8 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000002149 192.0
HKD1_k127_3121005_9 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000001353 181.0
HKD1_k127_3121345_0 Involved in the tonB-independent uptake of proteins - - - 4.454e-202 654.0
HKD1_k127_3121345_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 381.0
HKD1_k127_3137757_0 Involved in the tonB-independent uptake of proteins - - - 1.161e-216 713.0
HKD1_k127_3137757_1 Involved in the tonB-independent uptake of proteins - - - 9.446e-216 707.0
HKD1_k127_3137757_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000009625 256.0
HKD1_k127_3137757_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000001163 94.0
HKD1_k127_3140585_0 oxidoreductase activity K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 355.0
HKD1_k127_3140585_1 Glycosyl transferases group 1 - - - 0.00000000000000008578 94.0
HKD1_k127_3140585_2 Belongs to the UPF0434 family K09791 - - 0.00002282 57.0
HKD1_k127_3144786_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 431.0
HKD1_k127_3144786_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000002385 177.0
HKD1_k127_3148104_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
HKD1_k127_3148104_1 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001722 244.0
HKD1_k127_3153427_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 432.0
HKD1_k127_3153427_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000001985 214.0
HKD1_k127_3158038_0 Carbon starvation protein K06200 - - 0.0000000000000000000000000007829 118.0
HKD1_k127_3163637_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.983e-196 623.0
HKD1_k127_3163637_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 486.0
HKD1_k127_3163637_2 carbohydrate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 334.0
HKD1_k127_3163637_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
HKD1_k127_3163637_4 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002503 254.0
HKD1_k127_3165988_0 PFAM Peptidase M20 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 506.0
HKD1_k127_3165988_1 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
HKD1_k127_3165988_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00004705 51.0
HKD1_k127_3173665_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1021.0
HKD1_k127_3174166_0 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000006104 212.0
HKD1_k127_3174166_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000008 207.0
HKD1_k127_3174166_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000001742 124.0
HKD1_k127_3174166_3 Uncharacterised protein, DegV family COG1307 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000006957 102.0
HKD1_k127_3174166_4 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.0000000000000812 83.0
HKD1_k127_3174340_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.095e-254 797.0
HKD1_k127_3174340_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 543.0
HKD1_k127_3174340_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000004467 85.0
HKD1_k127_3174340_11 - - - - 0.00000000000008906 87.0
HKD1_k127_3174340_12 Redoxin K03564 - 1.11.1.15 0.000000007884 65.0
HKD1_k127_3174340_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 481.0
HKD1_k127_3174340_3 Surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000000363 267.0
HKD1_k127_3174340_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
HKD1_k127_3174340_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000001015 216.0
HKD1_k127_3174340_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000003558 217.0
HKD1_k127_3174340_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000006681 148.0
HKD1_k127_3174340_8 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000002678 122.0
HKD1_k127_3174340_9 Cytochrome c - - - 0.00000000000000000001183 105.0
HKD1_k127_3187162_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.46e-268 857.0
HKD1_k127_3187162_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 577.0
HKD1_k127_3187162_10 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000002817 198.0
HKD1_k127_3187162_11 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000004355 197.0
HKD1_k127_3187162_12 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000001533 182.0
HKD1_k127_3187162_13 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000005861 164.0
HKD1_k127_3187162_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000585 168.0
HKD1_k127_3187162_15 CoA carboxylase activity K01968 - 6.4.1.4 0.0000000000000000000000000000002005 128.0
HKD1_k127_3187162_16 - - - - 0.00000000000000000000000002404 124.0
HKD1_k127_3187162_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000004824 118.0
HKD1_k127_3187162_18 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000009438 115.0
HKD1_k127_3187162_19 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0000000000000000001398 99.0
HKD1_k127_3187162_2 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 580.0
HKD1_k127_3187162_20 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000001676 76.0
HKD1_k127_3187162_21 polysaccharide deacetylase K15531 - 3.2.1.156 0.00000000000008778 86.0
HKD1_k127_3187162_22 outer membrane autotransporter barrel domain protein - - - 0.00000000004504 71.0
HKD1_k127_3187162_23 Domain of unknown function DUF11 - - - 0.000000001587 72.0
HKD1_k127_3187162_24 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000002611 65.0
HKD1_k127_3187162_25 Htaa - - - 0.00000003366 66.0
HKD1_k127_3187162_26 Evidence 5 No homology to any previously reported sequences - - - 0.0000000711 66.0
HKD1_k127_3187162_27 Domain of unknown function DUF11 - - - 0.0000005408 63.0
HKD1_k127_3187162_29 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000145 55.0
HKD1_k127_3187162_3 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 337.0
HKD1_k127_3187162_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 340.0
HKD1_k127_3187162_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
HKD1_k127_3187162_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 303.0
HKD1_k127_3187162_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
HKD1_k127_3187162_8 SPTR Conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000008251 222.0
HKD1_k127_3187162_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000003777 205.0
HKD1_k127_3198600_0 Peptidase family M13 K07386 - - 8.402e-210 684.0
HKD1_k127_3198600_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 439.0
HKD1_k127_3198600_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000003468 141.0
HKD1_k127_3198600_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000001418 142.0
HKD1_k127_3198600_12 Pfam:UPF0118 - - - 0.0000000000000000000000000000002389 137.0
HKD1_k127_3198600_13 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000001521 134.0
HKD1_k127_3198600_14 phosphorelay signal transduction system - - - 0.00000000000000000000000000003577 132.0
HKD1_k127_3198600_15 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000009412 129.0
HKD1_k127_3198600_16 - - - - 0.000000000000000000000000002522 115.0
HKD1_k127_3198600_17 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000501 95.0
HKD1_k127_3198600_18 chlorophyll binding - - - 0.00000000000003115 87.0
HKD1_k127_3198600_19 PFAM Cache, type 2 - - - 0.00000000001125 77.0
HKD1_k127_3198600_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 366.0
HKD1_k127_3198600_21 - - - - 0.00005999 55.0
HKD1_k127_3198600_3 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 330.0
HKD1_k127_3198600_4 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
HKD1_k127_3198600_5 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000005168 273.0
HKD1_k127_3198600_6 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001461 237.0
HKD1_k127_3198600_7 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000008961 233.0
HKD1_k127_3198600_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.0000000000000000000000000000000000000000000000000002506 207.0
HKD1_k127_3198600_9 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000003283 167.0
HKD1_k127_3198736_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.566e-282 892.0
HKD1_k127_3198736_1 acetyltransferase (GNAT) family K03823 - 2.3.1.183 0.000000000000000000000000000000006154 129.0
HKD1_k127_3198736_2 Metallo-beta-lactamase superfamily - - - 0.000000000003405 71.0
HKD1_k127_3208001_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 360.0
HKD1_k127_3208001_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000502 117.0
HKD1_k127_3208001_2 N-6 DNA Methylase - - - 0.0000000000000000001285 98.0
HKD1_k127_3208001_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000002017 53.0
HKD1_k127_3208001_4 Type II transport protein GspH K08084 - - 0.0000009011 59.0
HKD1_k127_3208001_5 type IV pilus modification protein PilV K02458,K02671 - - 0.00008696 53.0
HKD1_k127_3208001_6 PilX N-terminal - - - 0.0008163 48.0
HKD1_k127_3211381_0 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000002165 211.0
HKD1_k127_3211381_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000007244 191.0
HKD1_k127_3211381_2 Spore Coat K01790 - 5.1.3.13 0.000000000000000000000000000006914 127.0
HKD1_k127_3211381_3 Iron-sulfur cluster-binding domain - - - 0.000000000008143 76.0
HKD1_k127_3211381_4 Hep Hag repeat protein - - - 0.000000006689 69.0
HKD1_k127_3223581_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1066.0
HKD1_k127_3223581_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 537.0
HKD1_k127_3223581_2 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 551.0
HKD1_k127_3223581_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 256.0
HKD1_k127_3223581_4 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000245 230.0
HKD1_k127_3223581_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000001522 217.0
HKD1_k127_3223581_6 (2Fe-2S) binding domain protein K03518,K16879 - 1.2.5.3,1.3.99.8 0.00000000000000000000000000000000000000000000000000008078 214.0
HKD1_k127_3224373_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 301.0
HKD1_k127_3224373_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 298.0
HKD1_k127_3224373_2 Helix-turn-helix domain - - - 0.000000000000003417 89.0
HKD1_k127_3224373_3 protein-glutamate methylesterase activity K03412,K03413,K18876 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 3.1.1.61,3.5.1.44 0.000000000003061 80.0
HKD1_k127_3224373_4 - - - - 0.000000001104 70.0
HKD1_k127_3224858_0 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000817 145.0
HKD1_k127_3224858_1 endonuclease activity K07451 - - 0.0000000000000002135 85.0
HKD1_k127_3236027_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 312.0
HKD1_k127_3236027_1 cheY-homologous receiver domain - - - 0.00000000000000000000000002442 113.0
HKD1_k127_3241352_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.921e-222 713.0
HKD1_k127_3241352_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 458.0
HKD1_k127_3241352_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
HKD1_k127_3241352_11 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 327.0
HKD1_k127_3241352_12 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 317.0
HKD1_k127_3241352_13 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000042 293.0
HKD1_k127_3241352_14 polyphosphate kinase activity K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007247 306.0
HKD1_k127_3241352_15 Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 265.0
HKD1_k127_3241352_16 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001307 269.0
HKD1_k127_3241352_17 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000006843 238.0
HKD1_k127_3241352_18 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000005317 243.0
HKD1_k127_3241352_19 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000001921 213.0
HKD1_k127_3241352_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 444.0
HKD1_k127_3241352_20 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000001227 225.0
HKD1_k127_3241352_21 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000006823 212.0
HKD1_k127_3241352_22 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000001747 194.0
HKD1_k127_3241352_23 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000005627 196.0
HKD1_k127_3241352_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000002152 122.0
HKD1_k127_3241352_25 Small Multidrug Resistance protein K11741 - - 0.0000000000000007758 83.0
HKD1_k127_3241352_27 Tetratricopeptide repeat - - - 0.000002698 61.0
HKD1_k127_3241352_28 Peptidase M56 - - - 0.00008228 53.0
HKD1_k127_3241352_29 PFAM Pectate lyase - - - 0.00009838 53.0
HKD1_k127_3241352_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 450.0
HKD1_k127_3241352_30 PFAM CHAD domain containing protein - - - 0.0007475 51.0
HKD1_k127_3241352_4 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
HKD1_k127_3241352_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 398.0
HKD1_k127_3241352_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 381.0
HKD1_k127_3241352_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 373.0
HKD1_k127_3241352_8 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 374.0
HKD1_k127_3241352_9 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 351.0
HKD1_k127_3265239_0 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000001372 167.0
HKD1_k127_3265239_1 - - - - 0.0000000000000000000002867 107.0
HKD1_k127_3265239_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000003142 108.0
HKD1_k127_3271525_0 Protein kinase domain K12132 - 2.7.11.1 6.914e-202 659.0
HKD1_k127_3271525_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 341.0
HKD1_k127_3271525_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000002894 202.0
HKD1_k127_3272994_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 461.0
HKD1_k127_3272994_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 436.0
HKD1_k127_3272994_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006774 73.0
HKD1_k127_3272994_11 - - - - 0.00008896 51.0
HKD1_k127_3272994_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 432.0
HKD1_k127_3272994_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 380.0
HKD1_k127_3272994_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 287.0
HKD1_k127_3272994_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000006661 233.0
HKD1_k127_3272994_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004179 219.0
HKD1_k127_3272994_7 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000005688 203.0
HKD1_k127_3272994_8 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000009569 135.0
HKD1_k127_3272994_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000275 116.0
HKD1_k127_3281769_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 364.0
HKD1_k127_3281769_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 315.0
HKD1_k127_3281769_10 cell septum assembly K02487,K06596,K08372 - - 0.00000000000004418 82.0
HKD1_k127_3281769_11 alpha-L-arabinofuranosidase - - - 0.00000002603 67.0
HKD1_k127_3281769_12 TIGRFAM polymorphic outer membrane protein K21449 - - 0.000985 52.0
HKD1_k127_3281769_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 301.0
HKD1_k127_3281769_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000172 291.0
HKD1_k127_3281769_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000444 298.0
HKD1_k127_3281769_5 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HKD1_k127_3281769_6 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002715 260.0
HKD1_k127_3281769_7 Pro-kumamolisin, activation domain K08677 - - 0.00000000000000000000000000000000000000000000000004806 206.0
HKD1_k127_3281769_8 Transcriptional regulator K03641 - - 0.00000000000000000002025 93.0
HKD1_k127_3281769_9 Tryptophan halogenase - - - 0.000000000000000002107 91.0
HKD1_k127_3281976_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 453.0
HKD1_k127_3281976_1 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000001644 279.0
HKD1_k127_3281976_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000003687 198.0
HKD1_k127_3295397_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 8e-323 1007.0
HKD1_k127_3295397_1 Belongs to the glycosyl hydrolase 31 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 493.0
HKD1_k127_3295397_2 heat shock protein binding - - - 0.0000001404 63.0
HKD1_k127_3306132_0 Peptidase family M49 - - - 2.858e-217 693.0
HKD1_k127_3306132_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 435.0
HKD1_k127_3306132_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 323.0
HKD1_k127_3306132_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 306.0
HKD1_k127_3306132_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001137 222.0
HKD1_k127_3306132_5 EamA-like transporter family - - - 0.00000000000000000000000000002667 132.0
HKD1_k127_3306132_6 Belongs to the GcvT family K06980 - - 0.0000000000000002333 95.0
HKD1_k127_3306716_0 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 472.0
HKD1_k127_3306716_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 364.0
HKD1_k127_3306716_10 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 0.0000000000001126 71.0
HKD1_k127_3306716_11 Domain of unknown function (DUF4390) - - - 0.00004881 53.0
HKD1_k127_3306716_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001677 280.0
HKD1_k127_3306716_3 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002208 280.0
HKD1_k127_3306716_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000343 254.0
HKD1_k127_3306716_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000001861 226.0
HKD1_k127_3306716_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000001029 201.0
HKD1_k127_3306716_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000008246 209.0
HKD1_k127_3306716_8 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000002666 172.0
HKD1_k127_3306716_9 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000003126 130.0
HKD1_k127_3313143_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 451.0
HKD1_k127_3313143_1 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 379.0
HKD1_k127_3313143_2 Domain of unknown function (DUF1972) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 357.0
HKD1_k127_3313143_3 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000007464 202.0
HKD1_k127_3313143_4 - - - - 0.0000000000000000000000000000000000000003536 158.0
HKD1_k127_3313143_5 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000242 139.0
HKD1_k127_3313143_6 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000002632 117.0
HKD1_k127_3313143_7 fatty acid desaturase - - - 0.000004404 50.0
HKD1_k127_3313143_8 Glycosyltransferase family 92 - - - 0.0002483 50.0
HKD1_k127_3317332_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.501e-270 845.0
HKD1_k127_3317332_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 576.0
HKD1_k127_3317332_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 534.0
HKD1_k127_3317332_3 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
HKD1_k127_3319518_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.786e-260 825.0
HKD1_k127_3319518_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000002292 206.0
HKD1_k127_3319518_2 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00004286 49.0
HKD1_k127_3325837_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000007213 270.0
HKD1_k127_3325837_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000002064 63.0
HKD1_k127_3325837_3 SMART Rhodanese domain protein - - - 0.0000439 46.0
HKD1_k127_3333195_0 Protein kinase domain K12132 - 2.7.11.1 8.579e-218 721.0
HKD1_k127_3333195_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 418.0
HKD1_k127_3333195_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 346.0
HKD1_k127_3333195_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000283 240.0
HKD1_k127_3333195_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000002669 208.0
HKD1_k127_3333195_5 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000003814 171.0
HKD1_k127_3333195_6 DinB family - - - 0.0001298 51.0
HKD1_k127_3338966_0 protein catabolic process K03420,K13525,K17681 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 366.0
HKD1_k127_3338966_1 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003628 301.0
HKD1_k127_3338966_2 - - - - 0.000000000000003178 87.0
HKD1_k127_3338966_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000001315 78.0
HKD1_k127_3338966_4 Mo-co oxidoreductase dimerisation domain - - - 0.00000004024 66.0
HKD1_k127_3341440_0 - - - - 0.0000000000000000000000000000000000000000003102 175.0
HKD1_k127_3346116_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 424.0
HKD1_k127_3346116_1 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 353.0
HKD1_k127_3346116_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000001515 227.0
HKD1_k127_3346116_3 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000002366 165.0
HKD1_k127_3346116_4 Methyltransferase domain - - - 0.0000000000000000000000000000000005137 141.0
HKD1_k127_3352664_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000006012 224.0
HKD1_k127_3433883_0 ABC transporter K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 1.381e-196 628.0
HKD1_k127_3433883_1 sequence-specific DNA binding K03719,K05800 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000443 149.0
HKD1_k127_3433883_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000009835 140.0
HKD1_k127_3433883_3 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000002086 140.0
HKD1_k127_3444797_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 512.0
HKD1_k127_3444797_1 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 297.0
HKD1_k127_3444797_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000002917 231.0
HKD1_k127_3444797_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000103 175.0
HKD1_k127_3444797_4 - - - - 0.00000000000000000000000000000000000000005677 170.0
HKD1_k127_3444797_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000003005 114.0
HKD1_k127_3444797_6 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000001332 98.0
HKD1_k127_3444797_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000001518 85.0
HKD1_k127_3465996_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 323.0
HKD1_k127_3471674_0 Sigma-54 interaction domain K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 583.0
HKD1_k127_3471674_1 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 308.0
HKD1_k127_3471674_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000002032 185.0
HKD1_k127_3471674_3 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000001384 177.0
HKD1_k127_3471674_4 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000002973 55.0
HKD1_k127_3483584_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 430.0
HKD1_k127_3483584_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001763 267.0
HKD1_k127_3483584_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000336 217.0
HKD1_k127_3483584_3 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000001362 208.0
HKD1_k127_3483584_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000002742 137.0
HKD1_k127_3483584_5 zinc-ribbon domain - - - 0.000000000004971 78.0
HKD1_k127_3483584_6 Histidine kinase - - - 0.00000009815 62.0
HKD1_k127_34961_0 COG3209 Rhs family protein - - - 0.00000000000000009087 95.0
HKD1_k127_34961_1 COG3209 Rhs family protein - - - 0.000000000000003327 91.0
HKD1_k127_3518928_0 MacB-like periplasmic core domain - - - 2.958e-293 930.0
HKD1_k127_3518928_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005477 250.0
HKD1_k127_3518928_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000832 192.0
HKD1_k127_3518928_3 RNA polymerase sigma factor - - - 0.00000000000000000006829 94.0
HKD1_k127_3518928_4 Glycosyl hydrolases family 28 - - - 0.0000000000000000001753 103.0
HKD1_k127_3518928_5 metallopeptidase activity K01637 - 4.1.3.1 0.000000003838 68.0
HKD1_k127_3535106_0 metallopeptidase activity - - - 5.795e-207 658.0
HKD1_k127_3541797_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
HKD1_k127_3541797_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000008026 240.0
HKD1_k127_3541797_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000505 235.0
HKD1_k127_3541797_3 EamA-like transporter family - - - 0.000000000000000000000001514 106.0
HKD1_k127_3541797_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000001338 89.0
HKD1_k127_3541797_5 Protein of unknown function (DUF2662) - - - 0.0000000000454 72.0
HKD1_k127_3547750_0 cellulose binding - - - 0.0 1048.0
HKD1_k127_3547750_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
HKD1_k127_3547750_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000006394 181.0
HKD1_k127_3547750_12 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000018 137.0
HKD1_k127_3547750_13 Methyltransferase domain - - - 0.00000000000000000000000000000004491 134.0
HKD1_k127_3547750_14 EVE domain - - - 0.000000000000000000000002504 111.0
HKD1_k127_3547750_15 repeat protein - - - 0.000000000000000000000003311 114.0
HKD1_k127_3547750_16 DinB superfamily - - - 0.000000000000000000000006359 116.0
HKD1_k127_3547750_17 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000003322 87.0
HKD1_k127_3547750_18 FmdB family transcriptional regulator - - - 0.000000000000000000606 90.0
HKD1_k127_3547750_19 phosphorelay signal transduction system - - - 0.00000000000000001072 93.0
HKD1_k127_3547750_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
HKD1_k127_3547750_20 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000483 68.0
HKD1_k127_3547750_21 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000171 48.0
HKD1_k127_3547750_22 Cupin domain - - - 0.00003411 57.0
HKD1_k127_3547750_23 - - - - 0.00005686 57.0
HKD1_k127_3547750_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 362.0
HKD1_k127_3547750_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006261 290.0
HKD1_k127_3547750_5 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001027 217.0
HKD1_k127_3547750_6 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000007817 187.0
HKD1_k127_3547750_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000002713 207.0
HKD1_k127_3547750_8 MoeA domain protein domain I and II K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000000000000000000000000000000000000000000000004476 185.0
HKD1_k127_3547750_9 Doxx family K15977 - - 0.0000000000000000000000000000000000000000000002126 173.0
HKD1_k127_3549784_0 methylisocitrate lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 342.0
HKD1_k127_3549784_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000004358 192.0
HKD1_k127_355611_0 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000354 123.0
HKD1_k127_355611_1 Glycosyl transferase family 21 - - - 0.000007279 57.0
HKD1_k127_3579429_0 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 460.0
HKD1_k127_3579429_1 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005841 277.0
HKD1_k127_3579429_2 - - - - 0.000000000000000000000000000000000000000000000000000004803 196.0
HKD1_k127_3579429_3 peptidase - - - 0.000000000000000000000000000000000001633 154.0
HKD1_k127_3579429_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000006979 115.0
HKD1_k127_3579429_5 esterase K03930 - - 0.00001926 51.0
HKD1_k127_358276_1 chlorophyll binding K16191,K20276 - - 0.00000003489 66.0
HKD1_k127_358895_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 567.0
HKD1_k127_358895_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 297.0
HKD1_k127_358895_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000004209 234.0
HKD1_k127_358895_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000002628 78.0
HKD1_k127_3607109_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 505.0
HKD1_k127_3607109_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 408.0
HKD1_k127_3607109_2 - - - - 0.00000000000005946 79.0
HKD1_k127_3607109_3 - - - - 0.00000001981 64.0
HKD1_k127_36258_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 306.0
HKD1_k127_36258_1 Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001678 265.0
HKD1_k127_3637713_0 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005072 263.0
HKD1_k127_3637713_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009259 263.0
HKD1_k127_3637713_2 - - - - 0.000000000000000000000000000001643 130.0
HKD1_k127_3637713_3 Thioredoxin-like - - - 0.000000000000000000002972 104.0
HKD1_k127_3637713_5 phosphate ion binding K02040 - - 0.00000000004108 77.0
HKD1_k127_3648896_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 384.0
HKD1_k127_3648896_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008126 290.0
HKD1_k127_3648896_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001819 262.0
HKD1_k127_3648896_3 PFAM Peptidase M23 - - - 0.000000000000000006135 98.0
HKD1_k127_3648896_4 O-antigen polymerase K18814 - - 0.0003469 52.0
HKD1_k127_3691138_0 Carbon starvation protein K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 613.0
HKD1_k127_3691138_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HKD1_k127_3691138_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000001573 177.0
HKD1_k127_3691138_3 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000004636 181.0
HKD1_k127_3691138_4 TrkA-N domain K03499 - - 0.00000000000000000002043 104.0
HKD1_k127_3691138_5 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000001692 92.0
HKD1_k127_3720213_0 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 347.0
HKD1_k127_3720213_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000005343 185.0
HKD1_k127_3720213_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000001169 127.0
HKD1_k127_3720213_3 Two component regulator propeller - - - 0.0000000000000000002943 100.0
HKD1_k127_3720213_4 DJ-1/PfpI family - - - 0.0000000009183 65.0
HKD1_k127_3720213_5 Tfp pilus assembly protein FimV - - - 0.000000012 69.0
HKD1_k127_3796765_0 aconitate hydratase K01681 - 4.2.1.3 3.185e-266 834.0
HKD1_k127_3796765_1 cellulose binding - - - 0.0000000000000000000000001503 112.0
HKD1_k127_385099_0 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000006856 123.0
HKD1_k127_385099_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000002293 96.0
HKD1_k127_385099_2 Protein of unknown function (DUF1328) - - - 0.0002065 44.0
HKD1_k127_385099_3 - - - - 0.0006812 52.0
HKD1_k127_3878158_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 7.356e-227 711.0
HKD1_k127_3878158_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 573.0
HKD1_k127_3878158_10 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00004652 55.0
HKD1_k127_3878158_11 phosphorelay signal transduction system - - - 0.00007266 56.0
HKD1_k127_3878158_2 PFAM Alpha beta hydrolase K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 435.0
HKD1_k127_3878158_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003519 282.0
HKD1_k127_3878158_4 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000002759 209.0
HKD1_k127_3878158_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000004346 192.0
HKD1_k127_3878158_6 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000263 197.0
HKD1_k127_3878158_7 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000004389 177.0
HKD1_k127_3878158_8 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000005576 134.0
HKD1_k127_3878158_9 COG3209 Rhs family protein - - - 0.000000000000003038 87.0
HKD1_k127_389263_0 Sortilin, neurotensin receptor 3, - - - 0.0 1094.0
HKD1_k127_389263_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 593.0
HKD1_k127_389263_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 525.0
HKD1_k127_389263_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 429.0
HKD1_k127_389263_4 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000001819 217.0
HKD1_k127_389263_5 tRNA m6t6A37 methyltransferase activity K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000009263 188.0
HKD1_k127_389263_6 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000001722 206.0
HKD1_k127_3899818_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000002296 226.0
HKD1_k127_3899818_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000006336 143.0
HKD1_k127_3899818_2 FAD binding domain K00380 - 1.8.1.2 0.000000000000000001043 94.0
HKD1_k127_3899818_3 polysaccharide deacetylase - - - 0.0000000001119 75.0
HKD1_k127_391190_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 449.0
HKD1_k127_391190_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000008322 139.0
HKD1_k127_392705_0 Belongs to the transketolase family K00615 - 2.2.1.1 2.299e-254 812.0
HKD1_k127_392705_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 584.0
HKD1_k127_392705_10 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 267.0
HKD1_k127_392705_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
HKD1_k127_392705_12 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000001087 198.0
HKD1_k127_392705_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000007695 198.0
HKD1_k127_392705_14 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000001452 170.0
HKD1_k127_392705_15 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000001886 107.0
HKD1_k127_392705_16 antisigma factor binding - - - 0.000000000000000000003657 101.0
HKD1_k127_392705_17 YXWGXW repeat (2 copies) - - - 0.00000000000000002213 96.0
HKD1_k127_392705_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 536.0
HKD1_k127_392705_3 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 462.0
HKD1_k127_392705_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 458.0
HKD1_k127_392705_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 438.0
HKD1_k127_392705_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 407.0
HKD1_k127_392705_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 394.0
HKD1_k127_392705_8 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 349.0
HKD1_k127_392705_9 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009646 288.0
HKD1_k127_393281_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006229 286.0
HKD1_k127_393281_1 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000001238 233.0
HKD1_k127_393281_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000001894 166.0
HKD1_k127_393281_3 - - - - 0.00000000000000000000000007816 124.0
HKD1_k127_3939734_0 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 288.0
HKD1_k127_3939734_1 PFAM Hly-III family protein K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
HKD1_k127_3939734_2 ABC transporter, substrate-binding protein, family 5 - - - 0.0000000000000000000000000000000000000000000000000000000000001578 232.0
HKD1_k127_3939734_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000005739 180.0
HKD1_k127_3939734_4 Protein of unknown function, DUF255 - - - 0.000000000000003084 86.0
HKD1_k127_4025780_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.855e-244 780.0
HKD1_k127_4025780_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000003123 66.0
HKD1_k127_4029040_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 305.0
HKD1_k127_4029040_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000169 263.0
HKD1_k127_4029040_2 Hep Hag repeat protein K21449 - - 0.0000000000000000000000000000000000000000000000000000001062 217.0
HKD1_k127_4029040_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000001646 75.0
HKD1_k127_4035273_0 M3B, thimet oligopeptidase F K01392 - 3.4.24.15 1.578e-251 788.0
HKD1_k127_4035273_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
HKD1_k127_4035273_2 peptidase - - - 0.00000000000000007525 85.0
HKD1_k127_4038030_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1287.0
HKD1_k127_4038030_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 411.0
HKD1_k127_4043811_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000007688 114.0
HKD1_k127_4043811_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000007036 85.0
HKD1_k127_4049915_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000004813 259.0
HKD1_k127_4049915_1 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000001161 220.0
HKD1_k127_4049915_2 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000002142 182.0
HKD1_k127_4050687_0 Belongs to the aldehyde dehydrogenase family K22187 - - 2.704e-206 653.0
HKD1_k127_4050687_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 453.0
HKD1_k127_4050687_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 375.0
HKD1_k127_4050687_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000001821 101.0
HKD1_k127_4050687_4 Protein conserved in bacteria - - - 0.000000000000007137 85.0
HKD1_k127_4052422_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 418.0
HKD1_k127_4052422_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 368.0
HKD1_k127_4052422_10 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 264.0
HKD1_k127_4052422_11 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
HKD1_k127_4052422_12 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000001525 209.0
HKD1_k127_4052422_13 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000006686 199.0
HKD1_k127_4052422_14 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.0000000000000000000000000000000000000000000002536 177.0
HKD1_k127_4052422_15 peroxiredoxin activity - - - 0.00000000000000000000000000000000000001774 160.0
HKD1_k127_4052422_16 Iodothyronine deiodinase - - - 0.0000000000000000000000000001302 119.0
HKD1_k127_4052422_17 Ribosomal L32p protein family K02911 - - 0.000000000000000000000007467 102.0
HKD1_k127_4052422_18 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000005586 97.0
HKD1_k127_4052422_19 cell redox homeostasis - - - 0.000000000000000001376 98.0
HKD1_k127_4052422_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 387.0
HKD1_k127_4052422_3 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 356.0
HKD1_k127_4052422_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 357.0
HKD1_k127_4052422_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 338.0
HKD1_k127_4052422_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001385 284.0
HKD1_k127_4052422_7 PFAM ATP dependent DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
HKD1_k127_4052422_8 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000005302 265.0
HKD1_k127_4052422_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005532 267.0
HKD1_k127_4058147_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000004366 197.0
HKD1_k127_4058147_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000003236 205.0
HKD1_k127_4058147_2 Protein tyrosine kinase - - - 0.000000000000000000000006837 120.0
HKD1_k127_4058147_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02341 - 2.7.7.7 0.000000000000000007125 100.0
HKD1_k127_4070162_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 562.0
HKD1_k127_4070162_1 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 449.0
HKD1_k127_4070162_2 nucleic acid phosphodiester bond hydrolysis K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000009906 234.0
HKD1_k127_4070162_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000522 99.0
HKD1_k127_4078714_0 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000002129 90.0
HKD1_k127_4078714_1 Bacterial membrane protein YfhO - - - 0.000000000001753 81.0
HKD1_k127_4092618_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 1.14e-322 994.0
HKD1_k127_4092618_1 peptidoglycan-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 355.0
HKD1_k127_4092618_2 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000002977 199.0
HKD1_k127_4092618_3 - - - - 0.000000000001312 75.0
HKD1_k127_4092724_0 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000001522 206.0
HKD1_k127_4092724_1 cyclohydrolase K01746 - 4.3.1.4 0.0000000000000000000000000000000005885 140.0
HKD1_k127_4092724_2 - - - - 0.0007768 49.0
HKD1_k127_4096084_0 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 415.0
HKD1_k127_4096084_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 394.0
HKD1_k127_4096084_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 376.0
HKD1_k127_4096084_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004765 313.0
HKD1_k127_4096084_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008601 282.0
HKD1_k127_4096084_5 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000002259 256.0
HKD1_k127_4096084_6 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000004706 145.0
HKD1_k127_4096084_7 Belongs to the SEDS family K03588 - - 0.000000000000000004464 91.0
HKD1_k127_4098238_0 protein conserved in bacteria K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 441.0
HKD1_k127_4098238_1 Phenazine biosynthesis-like protein K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000118 233.0
HKD1_k127_4098238_3 membrane - - - 0.00000000002972 76.0
HKD1_k127_4103591_0 Serine aminopeptidase, S33 - - - 0.000000000000000000002225 108.0
HKD1_k127_4103591_1 NUDIX domain K03575 - - 0.000000000000000000002265 100.0
HKD1_k127_4105557_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 294.0
HKD1_k127_4105557_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000001231 190.0
HKD1_k127_4105557_2 - - - - 0.00000000000000002414 93.0
HKD1_k127_4108040_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
HKD1_k127_4108040_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 343.0
HKD1_k127_4108040_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001264 296.0
HKD1_k127_4121560_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.455e-211 677.0
HKD1_k127_4121560_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 400.0
HKD1_k127_4121560_2 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000009066 190.0
HKD1_k127_4121560_3 HTH domain - - - 0.000000000000000001244 88.0
HKD1_k127_4121560_4 Lamin Tail Domain K07004 - - 0.000000000000003437 83.0
HKD1_k127_4121560_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000005797 60.0
HKD1_k127_4121560_6 extracellular matrix structural constituent - - - 0.0000004742 60.0
HKD1_k127_4141255_2 Protein of unknown function (DUF1624) - - - 0.00000000004734 63.0
HKD1_k127_4155895_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 319.0
HKD1_k127_4155895_1 TIGRFAM MJ0042 family finger-like protein - - - 0.0000718 50.0
HKD1_k127_4164408_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.466e-221 733.0
HKD1_k127_4164408_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000004338 181.0
HKD1_k127_4172494_0 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 316.0
HKD1_k127_4172494_1 domain, Protein - - - 0.0000000000001462 78.0
HKD1_k127_4172494_2 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.00000007105 65.0
HKD1_k127_4194557_0 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000002609 161.0
HKD1_k127_4194557_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000002726 128.0
HKD1_k127_4208490_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000001315 227.0
HKD1_k127_4208490_1 cellulose binding - - - 0.0000000000000000000000000000000000000000004615 178.0
HKD1_k127_4208490_2 TPM domain - - - 0.00000000000000000000000000000000000003488 148.0
HKD1_k127_4208490_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000001812 117.0
HKD1_k127_4226508_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 522.0
HKD1_k127_4226508_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000008764 145.0
HKD1_k127_4226508_2 YjbR - - - 0.0000000000000142 78.0
HKD1_k127_4226508_3 Phosphoenolpyruvate phosphomutase - - - 0.0000000001016 72.0
HKD1_k127_4235534_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 556.0
HKD1_k127_4235534_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000007186 166.0
HKD1_k127_4235534_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000769 79.0
HKD1_k127_4248110_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.078e-300 956.0
HKD1_k127_4248110_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 339.0
HKD1_k127_4248110_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006283 265.0
HKD1_k127_4248110_3 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HKD1_k127_4248110_4 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000003617 150.0
HKD1_k127_4248110_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000000000000002665 157.0
HKD1_k127_4248110_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000002494 72.0
HKD1_k127_4248110_7 Uncharacterized conserved protein (DUF2249) - - - 0.00000000001231 74.0
HKD1_k127_4248110_8 - - - - 0.0004679 46.0
HKD1_k127_4328800_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 361.0
HKD1_k127_4328800_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 345.0
HKD1_k127_4328800_2 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 295.0
HKD1_k127_4328800_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000116 224.0
HKD1_k127_4358521_0 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 347.0
HKD1_k127_4358521_1 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000005685 187.0
HKD1_k127_4358521_2 Glycosyltransferase like family 2 K00786,K16555,K19354 GO:0003674,GO:0003824,GO:0005575,GO:0006950,GO:0007154,GO:0008150,GO:0008194,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015020,GO:0016020,GO:0016036,GO:0016740,GO:0016757,GO:0016758,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000000000000000000001078 122.0
HKD1_k127_4359365_0 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
HKD1_k127_4359365_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001116 248.0
HKD1_k127_4359365_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000005361 228.0
HKD1_k127_4359365_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000004253 160.0
HKD1_k127_4365724_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 418.0
HKD1_k127_4365724_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 372.0
HKD1_k127_4365724_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000005362 76.0
HKD1_k127_4377138_0 DEAD DEAH box K03724 - - 0.0 1722.0
HKD1_k127_4377138_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 478.0
HKD1_k127_4377138_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 250.0
HKD1_k127_4377138_3 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
HKD1_k127_4377138_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000002969 165.0
HKD1_k127_4377138_5 - - - - 0.000000000000000000000001025 113.0
HKD1_k127_4377138_6 Putative zinc- or iron-chelating domain - - - 0.00000000000004291 85.0
HKD1_k127_4378093_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 388.0
HKD1_k127_4378093_1 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 328.0
HKD1_k127_4378093_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 339.0
HKD1_k127_4378093_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005178 295.0
HKD1_k127_4378093_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000002199 234.0
HKD1_k127_4378093_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001536 64.0
HKD1_k127_4378178_0 Bacterial protein of unknown function (DUF885) - - - 1.489e-244 769.0
HKD1_k127_4378178_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 392.0
HKD1_k127_4378178_2 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000149 267.0
HKD1_k127_4378178_3 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000009741 207.0
HKD1_k127_4378178_4 Ferredoxin - - - 0.0000000000000000000000000000004435 124.0
HKD1_k127_4378178_5 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000007499 123.0
HKD1_k127_4378178_6 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000002718 121.0
HKD1_k127_4378178_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000006918 109.0
HKD1_k127_4378178_8 - - - - 0.0000000179 59.0
HKD1_k127_4378178_9 Protein of unknown function (DUF983) - - - 0.0000001392 59.0
HKD1_k127_4381013_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 398.0
HKD1_k127_4381013_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 394.0
HKD1_k127_4381013_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000003631 154.0
HKD1_k127_4381013_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000003285 121.0
HKD1_k127_4416564_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000006173 224.0
HKD1_k127_4416564_1 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000002815 182.0
HKD1_k127_4416564_2 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000003007 166.0
HKD1_k127_4416564_3 Transposase - - - 0.00000000000000000000000000000001105 147.0
HKD1_k127_4416564_4 Glycosyl transferases group 1 - - - 0.000000000000001125 89.0
HKD1_k127_4416564_5 Acetyltransferase (GNAT) domain - - - 0.0000000000001969 84.0
HKD1_k127_4416564_6 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000009251 75.0
HKD1_k127_4420347_0 gluconolactonase activity K14274,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 384.0
HKD1_k127_4420347_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000002856 85.0
HKD1_k127_4420347_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000001889 79.0
HKD1_k127_4420347_3 Peptidase family M1 domain - - - 0.000000000000002267 90.0
HKD1_k127_4420347_4 - - - - 0.000006774 55.0
HKD1_k127_447115_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 437.0
HKD1_k127_447115_1 CAAX protease self-immunity - - - 0.000000000000000008443 84.0
HKD1_k127_4495208_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 3.05e-311 971.0
HKD1_k127_4495208_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005766 290.0
HKD1_k127_4495208_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007514 258.0
HKD1_k127_4495208_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000005636 187.0
HKD1_k127_4495208_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000000716 183.0
HKD1_k127_4495208_5 Tetratricopeptide repeat - - - 0.000000000000000000000000006086 126.0
HKD1_k127_4495208_6 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000009875 97.0
HKD1_k127_4495208_7 Pas domain - - - 0.00000000000001808 81.0
HKD1_k127_4505237_0 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 420.0
HKD1_k127_4505237_1 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000005403 220.0
HKD1_k127_4505237_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000001642 197.0
HKD1_k127_4505237_3 arylamine N-acetyltransferase activity - - - 0.000000000104 74.0
HKD1_k127_4505605_0 Multicopper oxidase K06324 - 1.16.3.3 3.089e-242 769.0
HKD1_k127_4505605_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000001918 211.0
HKD1_k127_4505605_2 Plasmid stabilization - - - 0.00000000000000000000000006344 109.0
HKD1_k127_4505605_3 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000004989 103.0
HKD1_k127_4505605_4 recA bacterial DNA recombination protein - - - 0.00000000000000004696 91.0
HKD1_k127_452277_0 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 588.0
HKD1_k127_452277_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000002565 107.0
HKD1_k127_452277_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000004546 109.0
HKD1_k127_4539326_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.147e-259 817.0
HKD1_k127_4539326_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.146e-243 790.0
HKD1_k127_4539326_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 532.0
HKD1_k127_4539326_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 413.0
HKD1_k127_4539326_4 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000002476 139.0
HKD1_k127_4539326_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000026 118.0
HKD1_k127_4539326_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000004173 79.0
HKD1_k127_4539326_7 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000139 74.0
HKD1_k127_4539326_8 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000009638 58.0
HKD1_k127_454539_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000005095 238.0
HKD1_k127_454539_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000001866 146.0
HKD1_k127_454539_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000794 123.0
HKD1_k127_454539_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000005096 81.0
HKD1_k127_454539_4 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000197 77.0
HKD1_k127_4551528_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 364.0
HKD1_k127_4551528_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000462 287.0
HKD1_k127_4554580_0 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 310.0
HKD1_k127_4554580_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000007817 158.0
HKD1_k127_4554580_3 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000004417 84.0
HKD1_k127_4554580_4 Peptidase family M50 - - - 0.000002218 51.0
HKD1_k127_4554580_5 Redoxin - - - 0.00005235 51.0
HKD1_k127_4562545_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 424.0
HKD1_k127_4562545_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 385.0
HKD1_k127_4562545_10 peptidase inhibitor activity - - - 0.00000000000007026 82.0
HKD1_k127_4562545_11 thiolester hydrolase activity K17362 - - 0.0000000000006192 74.0
HKD1_k127_4562545_12 cog cog0451 K00091 - 1.1.1.219 0.00000006023 55.0
HKD1_k127_4562545_2 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 341.0
HKD1_k127_4562545_3 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 336.0
HKD1_k127_4562545_4 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 326.0
HKD1_k127_4562545_5 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000005799 195.0
HKD1_k127_4562545_6 - K07018 - - 0.0000000000000000000000000000000000004739 153.0
HKD1_k127_4562545_7 AMMECR1 K09141 - - 0.000000000000000000000000000000000000796 162.0
HKD1_k127_4562545_8 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000002001 138.0
HKD1_k127_4562545_9 peptidase inhibitor activity - - - 0.00000000000001305 87.0
HKD1_k127_458070_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.577e-259 820.0
HKD1_k127_458070_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 499.0
HKD1_k127_458070_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000003165 256.0
HKD1_k127_458070_3 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000001811 130.0
HKD1_k127_459039_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000007903 189.0
HKD1_k127_459039_1 - - - - 0.000000000000000000000000000000000000000002116 162.0
HKD1_k127_4619587_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 597.0
HKD1_k127_4619587_1 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 334.0
HKD1_k127_4619587_10 ig-like, plexins, transcription factors - - - 0.00000000000000000000000000007071 134.0
HKD1_k127_4619587_11 phosphorelay signal transduction system - - - 0.00000000000000000000002047 103.0
HKD1_k127_4619587_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000002802 117.0
HKD1_k127_4619587_13 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.00000000375 68.0
HKD1_k127_4619587_14 Roadblock/LC7 domain - - - 0.000000005324 64.0
HKD1_k127_4619587_16 Predicted membrane protein (DUF2127) - - - 0.00002547 53.0
HKD1_k127_4619587_18 Domain of unknown function (DUF4118) - - - 0.0003224 51.0
HKD1_k127_4619587_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001232 287.0
HKD1_k127_4619587_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007204 228.0
HKD1_k127_4619587_4 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000001658 192.0
HKD1_k127_4619587_5 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000001472 205.0
HKD1_k127_4619587_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000002026 158.0
HKD1_k127_4619587_7 cell septum assembly - - - 0.0000000000000000000000000000000000004449 156.0
HKD1_k127_4619587_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000001104 162.0
HKD1_k127_4619587_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000001684 143.0
HKD1_k127_4646989_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 363.0
HKD1_k127_4646989_1 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000001593 87.0
HKD1_k127_4647916_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 433.0
HKD1_k127_4647916_1 Thioesterase - - - 0.000000000000000000004979 95.0
HKD1_k127_4654698_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.984e-283 883.0
HKD1_k127_4654698_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 517.0
HKD1_k127_4654698_2 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 360.0
HKD1_k127_4654698_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 377.0
HKD1_k127_4654698_4 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 359.0
HKD1_k127_4654698_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 304.0
HKD1_k127_4654698_6 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000001128 179.0
HKD1_k127_4654698_7 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00001179 55.0
HKD1_k127_4662028_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000002113 187.0
HKD1_k127_4662028_1 EamA-like transporter family - - - 0.00000000000000000000000000006184 131.0
HKD1_k127_4663319_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000006189 202.0
HKD1_k127_4663319_1 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.000000003696 70.0
HKD1_k127_4677283_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1272.0
HKD1_k127_4677283_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 375.0
HKD1_k127_4677283_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005814 271.0
HKD1_k127_4677283_3 - - - - 0.00000000134 61.0
HKD1_k127_4683643_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 486.0
HKD1_k127_4683643_1 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 354.0
HKD1_k127_4683643_10 - - - - 0.000000000004399 79.0
HKD1_k127_4683643_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 304.0
HKD1_k127_4683643_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000007268 228.0
HKD1_k127_4683643_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000002492 221.0
HKD1_k127_4683643_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000003571 166.0
HKD1_k127_4683643_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001031 154.0
HKD1_k127_4683643_7 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000008462 124.0
HKD1_k127_4683643_8 Histidine kinase-like ATPase domain - - - 0.00000000000000000000638 103.0
HKD1_k127_4683643_9 antisigma factor binding K06378,K07122 - - 0.00000000000000002511 92.0
HKD1_k127_4721651_0 Major facilitator superfamily K03446 - - 3.299e-196 623.0
HKD1_k127_4721651_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 562.0
HKD1_k127_4721651_10 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000000004856 196.0
HKD1_k127_4721651_11 Outer membrane efflux protein - - - 0.00000000000000000000000000003137 134.0
HKD1_k127_4721651_12 PFAM RNA recognition motif - - - 0.00000000000000000000000000006226 120.0
HKD1_k127_4721651_13 oxidoreductase activity - - - 0.000000000000000000000003181 119.0
HKD1_k127_4721651_14 COG3764 Sortase (surface protein transpeptidase) - - - 0.000000000000000000000004924 111.0
HKD1_k127_4721651_15 Translation Initiation Factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001446 106.0
HKD1_k127_4721651_17 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00002314 47.0
HKD1_k127_4721651_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 538.0
HKD1_k127_4721651_3 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 513.0
HKD1_k127_4721651_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
HKD1_k127_4721651_5 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001151 278.0
HKD1_k127_4721651_6 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001343 276.0
HKD1_k127_4721651_7 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003133 263.0
HKD1_k127_4721651_8 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005977 253.0
HKD1_k127_4721651_9 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000005473 244.0
HKD1_k127_473391_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 485.0
HKD1_k127_473391_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 391.0
HKD1_k127_473391_2 anion transmembrane transporter activity K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 298.0
HKD1_k127_473391_3 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000001038 132.0
HKD1_k127_473391_4 lipoprotein transporter activity K02003 - - 0.00000004774 55.0
HKD1_k127_473391_5 Antibiotic biosynthesis monooxygenase - - - 0.0001757 51.0
HKD1_k127_47585_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 344.0
HKD1_k127_47585_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
HKD1_k127_4781925_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000001227 235.0
HKD1_k127_4781925_1 Universal stress protein family - - - 0.000996 52.0
HKD1_k127_4887839_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000002383 220.0
HKD1_k127_4887839_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000001608 205.0
HKD1_k127_4887839_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000002599 83.0
HKD1_k127_4887839_3 lipase activity K15349 - - 0.0000000000000005481 93.0
HKD1_k127_5050917_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000003172 218.0
HKD1_k127_5050917_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001567 197.0
HKD1_k127_5050917_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000005507 143.0
HKD1_k127_5050917_3 Protein conserved in bacteria - - - 0.0000000000000000000000000003025 123.0
HKD1_k127_5069358_0 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 1.169e-199 634.0
HKD1_k127_5069358_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 432.0
HKD1_k127_5069358_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001837 284.0
HKD1_k127_5069358_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000003023 178.0
HKD1_k127_5069358_4 AAA domain K04562 - - 0.000000000000000008893 96.0
HKD1_k127_5069358_5 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000006878 89.0
HKD1_k127_5069358_6 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000001372 81.0
HKD1_k127_5092852_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.279e-204 655.0
HKD1_k127_5092852_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 439.0
HKD1_k127_5092852_2 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 385.0
HKD1_k127_5092852_3 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001661 256.0
HKD1_k127_5092852_4 Acid phosphatase homologues - - - 0.000000000000000000000000000001371 134.0
HKD1_k127_5092852_5 Leucine-rich repeat (LRR) protein - - - 0.000000000004947 78.0
HKD1_k127_5092852_6 Lysylphosphatidylglycerol synthase TM region - - - 0.000000124 59.0
HKD1_k127_5092852_7 Phosphorylase superfamily K01243 - 3.2.2.9 0.00003202 57.0
HKD1_k127_5092852_8 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00009384 47.0
HKD1_k127_5099821_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000008989 216.0
HKD1_k127_5099821_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000002407 177.0
HKD1_k127_5099821_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000001365 155.0
HKD1_k127_5099821_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000009911 115.0
HKD1_k127_5099822_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000006157 216.0
HKD1_k127_5099822_1 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000004972 179.0
HKD1_k127_5099822_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000007271 156.0
HKD1_k127_5109050_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 385.0
HKD1_k127_5109050_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 379.0
HKD1_k127_5109050_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 324.0
HKD1_k127_5109050_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000241 225.0
HKD1_k127_5109050_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000001168 128.0
HKD1_k127_5109050_5 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000006792 91.0
HKD1_k127_5109050_6 Protein of unknown function (FYDLN_acid) - - - 0.00000000000432 70.0
HKD1_k127_5109050_7 Tetratricopeptide repeat - - - 0.00003674 55.0
HKD1_k127_5134974_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 483.0
HKD1_k127_5134974_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 402.0
HKD1_k127_5134974_10 Chorismate mutase type II K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000001131 101.0
HKD1_k127_5134974_11 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000004059 63.0
HKD1_k127_5134974_12 Protein kinase domain K12132 - 2.7.11.1 0.0002458 47.0
HKD1_k127_5134974_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 353.0
HKD1_k127_5134974_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002485 259.0
HKD1_k127_5134974_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000001655 232.0
HKD1_k127_5134974_5 Peptidase C26 K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000064 217.0
HKD1_k127_5134974_6 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000005314 199.0
HKD1_k127_5134974_7 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000389 193.0
HKD1_k127_5134974_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000006237 145.0
HKD1_k127_5134974_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000001039 144.0
HKD1_k127_5153771_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1206.0
HKD1_k127_5153771_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 353.0
HKD1_k127_5153771_2 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 339.0
HKD1_k127_5153771_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 322.0
HKD1_k127_5153771_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000001921 127.0
HKD1_k127_5153771_5 YsiA-like protein, C-terminal region K13770 - - 0.000000000000001323 84.0
HKD1_k127_5153771_6 Protein of unknown function DUF72 - - - 0.00001574 49.0
HKD1_k127_5200022_0 ABC transporter K06020 - 3.6.3.25 3.893e-259 810.0
HKD1_k127_5200022_1 Pro-kumamolisin, activation domain K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 550.0
HKD1_k127_5200022_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001781 289.0
HKD1_k127_5200022_11 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002632 273.0
HKD1_k127_5200022_12 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007063 267.0
HKD1_k127_5200022_13 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000005773 253.0
HKD1_k127_5200022_14 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000001948 268.0
HKD1_k127_5200022_15 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001078 246.0
HKD1_k127_5200022_16 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000421 234.0
HKD1_k127_5200022_17 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000004285 228.0
HKD1_k127_5200022_18 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000007066 236.0
HKD1_k127_5200022_19 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000002661 217.0
HKD1_k127_5200022_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 490.0
HKD1_k127_5200022_20 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000103 208.0
HKD1_k127_5200022_21 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000002446 216.0
HKD1_k127_5200022_22 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000005814 207.0
HKD1_k127_5200022_23 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000005125 207.0
HKD1_k127_5200022_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000007244 191.0
HKD1_k127_5200022_25 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000001522 162.0
HKD1_k127_5200022_26 diguanylate cyclase - - - 0.000000000000000000000000000000000000006736 162.0
HKD1_k127_5200022_27 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005826 160.0
HKD1_k127_5200022_28 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000303 155.0
HKD1_k127_5200022_29 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000154 141.0
HKD1_k127_5200022_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 485.0
HKD1_k127_5200022_30 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000008402 126.0
HKD1_k127_5200022_31 Could be involved in septation K06412 - - 0.0000000000000000000000009719 117.0
HKD1_k127_5200022_32 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000001867 98.0
HKD1_k127_5200022_33 Universal stress protein family - - - 0.0000000000000000000004425 108.0
HKD1_k127_5200022_34 Response regulator receiver domain - - - 0.00000000000000000002998 106.0
HKD1_k127_5200022_35 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000005041 103.0
HKD1_k127_5200022_36 protein-disulfide reductase activity - - - 0.000000000000000007197 98.0
HKD1_k127_5200022_37 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000001098 90.0
HKD1_k127_5200022_38 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.0000000000000185 85.0
HKD1_k127_5200022_39 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000003262 79.0
HKD1_k127_5200022_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 402.0
HKD1_k127_5200022_40 Belongs to the UPF0109 family K06960 - - 0.000000000008317 72.0
HKD1_k127_5200022_41 - - - - 0.0000000001283 66.0
HKD1_k127_5200022_42 tRNA wobble adenosine to inosine editing - - - 0.0000003773 60.0
HKD1_k127_5200022_43 bacterial OsmY and nodulation domain - - - 0.00007286 54.0
HKD1_k127_5200022_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 369.0
HKD1_k127_5200022_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 330.0
HKD1_k127_5200022_7 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 369.0
HKD1_k127_5200022_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 351.0
HKD1_k127_5200022_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 319.0
HKD1_k127_5208062_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 356.0
HKD1_k127_5208062_1 Adenylate cyclase - - - 0.00000000000002456 81.0
HKD1_k127_5208062_2 FHA domain K07315 - 3.1.3.3 0.0000000001698 70.0
HKD1_k127_5209308_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 511.0
HKD1_k127_5209308_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 506.0
HKD1_k127_5209308_2 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 410.0
HKD1_k127_5209308_3 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000001189 277.0
HKD1_k127_5209308_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000009723 213.0
HKD1_k127_5209308_5 PFAM glycosyl transferase family 39 - - - 0.0000000000000001225 89.0
HKD1_k127_5212723_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 1.107e-247 787.0
HKD1_k127_5212723_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000001198 160.0
HKD1_k127_5215000_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 610.0
HKD1_k127_5215000_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 531.0
HKD1_k127_5215000_2 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001931 261.0
HKD1_k127_5215000_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000001502 172.0
HKD1_k127_5215000_4 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000092 141.0
HKD1_k127_5215000_5 YCII-related domain K09780 - - 0.0000000000000000000000000000005867 142.0
HKD1_k127_5215000_6 Rhodanese Homology Domain - - - 0.00000000000000000000000006616 117.0
HKD1_k127_5215000_7 Domain of unknown function (DUF5117) - - - 0.000000000000000000000001018 119.0
HKD1_k127_5215000_8 Lipopolysaccharide-assembly - - - 0.000000000000000001254 91.0
HKD1_k127_5215000_9 Domain of Unknown Function (DUF1206) - - - 0.00000000000008567 83.0
HKD1_k127_5217754_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 507.0
HKD1_k127_5217754_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 405.0
HKD1_k127_5217754_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000009068 269.0
HKD1_k127_5217754_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000001587 231.0
HKD1_k127_5217754_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000009375 202.0
HKD1_k127_5217754_5 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000005274 182.0
HKD1_k127_5217754_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000001481 199.0
HKD1_k127_5217754_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000001656 172.0
HKD1_k127_5217754_8 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000581 124.0
HKD1_k127_5217754_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000006543 66.0
HKD1_k127_5223615_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.312e-229 728.0
HKD1_k127_5223615_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 507.0
HKD1_k127_5223615_10 Glycosyl transferases group 1 K07011 - - 0.000000000000000000000000000000000000000000000000000000000004937 235.0
HKD1_k127_5223615_11 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000006932 220.0
HKD1_k127_5223615_12 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000005251 198.0
HKD1_k127_5223615_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000008281 178.0
HKD1_k127_5223615_14 ABC-2 type transporter K01992,K09690 - - 0.000000000000000000000000000000000000001625 170.0
HKD1_k127_5223615_15 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000006189 158.0
HKD1_k127_5223615_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000003942 101.0
HKD1_k127_5223615_17 Protein of unknown function (DUF3187) - - - 0.000001966 62.0
HKD1_k127_5223615_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 403.0
HKD1_k127_5223615_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 386.0
HKD1_k127_5223615_4 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 364.0
HKD1_k127_5223615_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 295.0
HKD1_k127_5223615_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005912 265.0
HKD1_k127_5223615_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000002787 241.0
HKD1_k127_5223615_8 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000003176 237.0
HKD1_k127_5223615_9 PFAM Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000158 228.0
HKD1_k127_5237697_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HKD1_k127_5237697_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 304.0
HKD1_k127_5239405_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.527e-232 747.0
HKD1_k127_5239405_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 534.0
HKD1_k127_5239405_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 471.0
HKD1_k127_5239405_3 sigma factor activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008416 248.0
HKD1_k127_5239405_4 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000004144 181.0
HKD1_k127_5239405_5 YCII-related domain - - - 0.00000000000000000000000000000000000001797 146.0
HKD1_k127_5239405_6 Domain of unknown function (DUF4440) - - - 0.000000001889 65.0
HKD1_k127_5239405_7 FAD linked oxidase domain protein - - - 0.0009522 42.0
HKD1_k127_5241680_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000004917 226.0
HKD1_k127_5241680_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000004663 191.0
HKD1_k127_5249517_0 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 517.0
HKD1_k127_5249517_1 Oxidative stress defense protein K09807 - - 0.0000000000000000000000000004815 123.0
HKD1_k127_5281555_0 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 576.0
HKD1_k127_5281555_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 513.0
HKD1_k127_5281555_2 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 389.0
HKD1_k127_5281555_3 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HKD1_k127_5281555_4 FAD linked oxidases, C-terminal domain K06911 - - 0.000000000000000000000000000000000000000000000004976 175.0
HKD1_k127_5281555_5 phosphorelay signal transduction system - - - 0.00000000000000000001757 97.0
HKD1_k127_5281555_6 COG2143 Thioredoxin-related protein - - - 0.00001268 57.0
HKD1_k127_5288379_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 427.0
HKD1_k127_5288379_1 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 381.0
HKD1_k127_5288379_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000109 179.0
HKD1_k127_5288379_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000392 136.0
HKD1_k127_5288379_5 PFAM RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.000000000000000000003177 100.0
HKD1_k127_5288379_6 Putative adhesin - - - 0.0000000000000421 86.0
HKD1_k127_5288379_7 redox protein, regulator of disulfide bond formation - - - 0.00000000003844 70.0
HKD1_k127_5288379_8 Protein of unknown function (DUF4230) - - - 0.00000000006407 74.0
HKD1_k127_5288379_9 HEAT repeats - - - 0.0000003838 63.0
HKD1_k127_528848_0 Dehydrogenase E1 component K11381 - 1.2.4.4 3.612e-312 982.0
HKD1_k127_528848_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000004657 235.0
HKD1_k127_528848_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000002605 179.0
HKD1_k127_528848_3 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000165 137.0
HKD1_k127_528848_4 protein kinase activity - - - 0.0000000000000000000568 105.0
HKD1_k127_528848_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000007141 94.0
HKD1_k127_528848_6 Protein of unknown function (DUF2905) - - - 0.0000001012 56.0
HKD1_k127_5295248_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.987e-319 1002.0
HKD1_k127_5295248_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 486.0
HKD1_k127_5295248_2 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 393.0
HKD1_k127_5295248_3 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 367.0
HKD1_k127_5295248_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 368.0
HKD1_k127_5295248_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000005428 105.0
HKD1_k127_5295248_6 RNA polymerase sigma factor, sigma-70 family - - - 0.0000005094 59.0
HKD1_k127_5308343_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 542.0
HKD1_k127_5308343_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 515.0
HKD1_k127_5308343_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000205 107.0
HKD1_k127_5308343_11 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000001741 104.0
HKD1_k127_5308343_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000004699 91.0
HKD1_k127_5308343_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 411.0
HKD1_k127_5308343_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 399.0
HKD1_k127_5308343_4 phosphoglucomutase phosphomannomutase alpha beta K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 353.0
HKD1_k127_5308343_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000006991 195.0
HKD1_k127_5308343_6 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000000000000164 202.0
HKD1_k127_5308343_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000005636 177.0
HKD1_k127_5308343_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000009613 165.0
HKD1_k127_5308343_9 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000007304 143.0
HKD1_k127_5331421_0 PFAM Protein synthesis factor, GTP-binding K06207 - - 3.459e-241 776.0
HKD1_k127_5331421_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000005988 190.0
HKD1_k127_5331421_2 - - - - 0.0000000000000000000004218 111.0
HKD1_k127_5331421_3 YigZ family - - - 0.00000000000008382 76.0
HKD1_k127_5331421_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000005089 65.0
HKD1_k127_5335028_0 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000225 226.0
HKD1_k127_5335028_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000001245 219.0
HKD1_k127_5335028_2 - - - - 0.0000000000000000000000000000000000000000001009 172.0
HKD1_k127_5335028_3 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000316 108.0
HKD1_k127_5335028_4 - - - - 0.000000000000000000004121 98.0
HKD1_k127_5335028_5 Domain of unknown function (DUF4136) - - - 0.00000000000000000001244 104.0
HKD1_k127_5335028_6 - - - - 0.0000000000003766 71.0
HKD1_k127_5335028_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000007225 64.0
HKD1_k127_5335028_8 Carbohydrate family 9 binding domain-like - - - 0.000001243 56.0
HKD1_k127_5342625_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000004531 129.0
HKD1_k127_5342625_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000002283 98.0
HKD1_k127_5353463_0 6-phospho-beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 457.0
HKD1_k127_5353463_1 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 409.0
HKD1_k127_5353463_2 spheroidene biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 275.0
HKD1_k127_5353463_3 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000007342 234.0
HKD1_k127_5353463_4 Bacterial membrane protein, YfhO - - - 0.00000000001086 74.0
HKD1_k127_5353463_5 transcriptional regulator, SARP family - - - 0.0006266 52.0
HKD1_k127_5355530_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.032e-266 841.0
HKD1_k127_5355530_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 358.0
HKD1_k127_5355530_10 - - - - 0.000000000000000000000000000000000000795 161.0
HKD1_k127_5355530_11 aminopeptidase activity - - - 0.000000000000000000000000000000000002221 152.0
HKD1_k127_5355530_12 - - - - 0.0000000000000000000000000000000002525 151.0
HKD1_k127_5355530_13 Hep Hag repeat protein K21449 - - 0.000000000000000005171 85.0
HKD1_k127_5355530_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 324.0
HKD1_k127_5355530_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001559 279.0
HKD1_k127_5355530_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007715 281.0
HKD1_k127_5355530_5 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000008934 227.0
HKD1_k127_5355530_6 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000006295 194.0
HKD1_k127_5355530_7 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000001141 181.0
HKD1_k127_5355530_8 - - - - 0.00000000000000000000000000000000000000000003083 185.0
HKD1_k127_5355530_9 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000004389 185.0
HKD1_k127_5357567_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004778 296.0
HKD1_k127_5357567_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000007894 177.0
HKD1_k127_5357567_2 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000001423 134.0
HKD1_k127_5361754_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000001222 178.0
HKD1_k127_5363418_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 372.0
HKD1_k127_5363418_1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000007603 85.0
HKD1_k127_5363418_2 Calcineurin-like phosphoesterase - - - 0.0006033 49.0
HKD1_k127_5378872_0 Peptidase, M16 K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 518.0
HKD1_k127_5378872_1 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 470.0
HKD1_k127_5378872_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000005522 245.0
HKD1_k127_5378872_3 Smr domain - - - 0.000000000000000000000001838 109.0
HKD1_k127_5378872_4 Alpha beta K06889 - - 0.00000000008702 73.0
HKD1_k127_5378872_5 - - - - 0.0000001097 58.0
HKD1_k127_53812_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 607.0
HKD1_k127_53812_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 264.0
HKD1_k127_53812_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000004639 157.0
HKD1_k127_53812_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000004171 93.0
HKD1_k127_5386252_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 430.0
HKD1_k127_5386252_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 435.0
HKD1_k127_544308_0 4Fe-4S dicluster domain - - - 3.06e-322 1009.0
HKD1_k127_544308_1 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.0000000000000000001491 89.0
HKD1_k127_545272_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 379.0
HKD1_k127_545272_1 Ion transport 2 domain protein K10716 - - 0.0000000000006915 71.0
HKD1_k127_545272_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000016 53.0
HKD1_k127_5483147_0 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
HKD1_k127_5483147_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 328.0
HKD1_k127_5483147_10 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000001976 224.0
HKD1_k127_5483147_11 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000001356 206.0
HKD1_k127_5483147_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000001276 192.0
HKD1_k127_5483147_13 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000002762 160.0
HKD1_k127_5483147_14 OmpA family K03640 - - 0.0000000000000000000000000000000000004824 146.0
HKD1_k127_5483147_15 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000009154 132.0
HKD1_k127_5483147_16 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000006243 126.0
HKD1_k127_5483147_17 Outer membrane lipoprotein - - - 0.0000000000000000000000008028 119.0
HKD1_k127_5483147_18 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000181 67.0
HKD1_k127_5483147_19 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.00000000002054 78.0
HKD1_k127_5483147_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006599 310.0
HKD1_k127_5483147_20 TonB C terminal K03832 - - 0.00003322 54.0
HKD1_k127_5483147_21 Metallo-beta-lactamase superfamily - - - 0.0003256 53.0
HKD1_k127_5483147_3 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000008349 269.0
HKD1_k127_5483147_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001026 269.0
HKD1_k127_5483147_5 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004443 250.0
HKD1_k127_5483147_6 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000418 230.0
HKD1_k127_5483147_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000005482 241.0
HKD1_k127_5483147_8 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000107 246.0
HKD1_k127_5483147_9 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000006486 222.0
HKD1_k127_548693_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 462.0
HKD1_k127_548693_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000001698 134.0
HKD1_k127_548693_2 Tetratricopeptide repeat - - - 0.0000000000000000000000004531 121.0
HKD1_k127_548693_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000009874 105.0
HKD1_k127_5510249_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
HKD1_k127_5510249_1 DinB family - - - 0.0000000000000000000000002808 121.0
HKD1_k127_5531148_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 430.0
HKD1_k127_5531148_1 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 298.0
HKD1_k127_5531148_10 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00001496 57.0
HKD1_k127_5531148_2 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
HKD1_k127_5531148_3 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000027 138.0
HKD1_k127_5531148_4 DinB superfamily K07552 - - 0.0000000000000000000000000003049 119.0
HKD1_k127_5531148_5 COG0517 FOG CBS domain - - - 0.000000000000000000001639 100.0
HKD1_k127_5531148_6 EamA-like transporter family - - - 0.00000000000001401 76.0
HKD1_k127_5531148_7 - - - - 0.00000000000001606 85.0
HKD1_k127_5531148_8 - - - - 0.00000000008895 74.0
HKD1_k127_5531148_9 - - - - 0.00000001172 63.0
HKD1_k127_5532932_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 7.907e-200 641.0
HKD1_k127_5532932_1 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 594.0
HKD1_k127_5532932_10 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000003782 247.0
HKD1_k127_5532932_11 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
HKD1_k127_5532932_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000001768 178.0
HKD1_k127_5532932_13 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000008394 176.0
HKD1_k127_5532932_14 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000947 188.0
HKD1_k127_5532932_15 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000003819 163.0
HKD1_k127_5532932_16 oxidoreductase activity - - - 0.000000000000000000000000000000002823 147.0
HKD1_k127_5532932_17 Thioredoxin-like - - - 0.00000000000000000000000000000174 127.0
HKD1_k127_5532932_18 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000005071 119.0
HKD1_k127_5532932_19 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000003965 126.0
HKD1_k127_5532932_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 495.0
HKD1_k127_5532932_20 Sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000002122 119.0
HKD1_k127_5532932_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000009304 100.0
HKD1_k127_5532932_22 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000004478 103.0
HKD1_k127_5532932_23 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000005589 90.0
HKD1_k127_5532932_24 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000008173 99.0
HKD1_k127_5532932_25 Tetratricopeptide repeat - - - 0.00000000000000003137 92.0
HKD1_k127_5532932_26 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000004501 95.0
HKD1_k127_5532932_27 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000496 83.0
HKD1_k127_5532932_28 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000005129 81.0
HKD1_k127_5532932_29 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000004194 86.0
HKD1_k127_5532932_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 461.0
HKD1_k127_5532932_30 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000004626 68.0
HKD1_k127_5532932_31 energy transducer activity K03832 - - 0.000007673 59.0
HKD1_k127_5532932_32 hydrogen-translocating pyrophosphatase activity K01507 - 3.6.1.1 0.0009593 44.0
HKD1_k127_5532932_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 369.0
HKD1_k127_5532932_5 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 371.0
HKD1_k127_5532932_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 353.0
HKD1_k127_5532932_7 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 355.0
HKD1_k127_5532932_8 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 331.0
HKD1_k127_5532932_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002468 311.0
HKD1_k127_5538929_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 2.97e-215 699.0
HKD1_k127_5538929_1 Adenylate cyclase - - - 0.000000000000000197 87.0
HKD1_k127_55879_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 9.185e-287 889.0
HKD1_k127_55879_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 500.0
HKD1_k127_55879_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00002658 55.0
HKD1_k127_55879_12 Domain of unknown function (DUF4149) - - - 0.0005676 52.0
HKD1_k127_55879_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 327.0
HKD1_k127_55879_3 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 316.0
HKD1_k127_55879_4 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 302.0
HKD1_k127_55879_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000003055 250.0
HKD1_k127_55879_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000002418 213.0
HKD1_k127_55879_7 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000002388 142.0
HKD1_k127_55879_8 Poly A polymerase, head domain K00970 - 2.7.7.19 0.000000000000000000000000000001448 138.0
HKD1_k127_55879_9 Putative Fe-S cluster K00380 - 1.8.1.2 0.00000000000000001131 96.0
HKD1_k127_5625470_0 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 543.0
HKD1_k127_5625470_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000005025 184.0
HKD1_k127_5667340_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 293.0
HKD1_k127_5667340_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000006154 168.0
HKD1_k127_5667340_2 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000003131 105.0
HKD1_k127_5667340_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000003938 59.0
HKD1_k127_5673058_0 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000004228 215.0
HKD1_k127_5673058_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000004929 99.0
HKD1_k127_5773796_0 Hep Hag repeat protein - - - 0.000000002546 70.0
HKD1_k127_5811145_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1035.0
HKD1_k127_5839155_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 428.0
HKD1_k127_5839155_1 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
HKD1_k127_5839155_2 permease - - - 0.00000000000000000000000000000000005083 148.0
HKD1_k127_5839155_3 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000001235 63.0
HKD1_k127_5854558_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.641e-311 961.0
HKD1_k127_5854558_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 5.631e-265 839.0
HKD1_k127_5854558_10 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000366 136.0
HKD1_k127_5854558_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000002527 133.0
HKD1_k127_5854558_2 Extracellular solute-binding protein K02027 - - 1.563e-216 683.0
HKD1_k127_5854558_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 440.0
HKD1_k127_5854558_4 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 443.0
HKD1_k127_5854558_5 Binding-protein-dependent transport system inner membrane component K02025,K10118,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 439.0
HKD1_k127_5854558_6 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 353.0
HKD1_k127_5854558_7 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002968 284.0
HKD1_k127_5854558_8 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
HKD1_k127_5854558_9 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000146 229.0
HKD1_k127_5857307_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 491.0
HKD1_k127_5857307_1 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 493.0
HKD1_k127_5857307_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 400.0
HKD1_k127_5857307_3 GGDEF domain - - - 0.0000000000000000000000000004625 123.0
HKD1_k127_5857307_4 Universal stress protein family - - - 0.00000000000000000000006918 102.0
HKD1_k127_5857307_5 PFAM CBS domain containing protein K07168 - - 0.0000000000000000000001896 112.0
HKD1_k127_5857307_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000005165 60.0
HKD1_k127_5915994_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002159 284.0
HKD1_k127_5915994_1 -O-antigen - - - 0.000000000000000000001475 108.0
HKD1_k127_5962867_0 peptidyl-tyrosine sulfation - - - 1.59e-216 692.0
HKD1_k127_5962867_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 577.0
HKD1_k127_5962867_10 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000005198 187.0
HKD1_k127_5962867_11 - - - - 0.00000000000000000000000000000000000000000000106 175.0
HKD1_k127_5962867_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000001228 154.0
HKD1_k127_5962867_13 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000002092 148.0
HKD1_k127_5962867_14 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000001272 144.0
HKD1_k127_5962867_15 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000005533 121.0
HKD1_k127_5962867_16 Transcriptional regulator - - - 0.0000000000000000003501 96.0
HKD1_k127_5962867_17 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000001356 96.0
HKD1_k127_5962867_19 lipoprotein involved in nitrous oxide reduction - - - 0.0000001247 65.0
HKD1_k127_5962867_2 Cytochrome C oxidase, subunit II K00376,K02275 - 1.7.2.4,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 552.0
HKD1_k127_5962867_20 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00007346 55.0
HKD1_k127_5962867_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 499.0
HKD1_k127_5962867_4 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 379.0
HKD1_k127_5962867_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 377.0
HKD1_k127_5962867_6 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 341.0
HKD1_k127_5962867_7 alginic acid biosynthetic process K07218 - - 0.000000000000000000000000000000000000000000000000000007815 213.0
HKD1_k127_5962867_8 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000146 201.0
HKD1_k127_5962867_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000003672 201.0
HKD1_k127_6039155_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 584.0
HKD1_k127_6039155_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 364.0
HKD1_k127_6039155_2 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
HKD1_k127_6039155_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 340.0
HKD1_k127_6039155_4 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 304.0
HKD1_k127_6039155_5 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006073 218.0
HKD1_k127_6039155_6 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000002642 179.0
HKD1_k127_6041314_0 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 368.0
HKD1_k127_6041314_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
HKD1_k127_6041314_2 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000004039 216.0
HKD1_k127_6041314_3 of the beta-lactamase K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000036 191.0
HKD1_k127_6041314_4 cog cog1502 K06131 - - 0.0000000000000000000002634 99.0
HKD1_k127_6049064_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 526.0
HKD1_k127_6049064_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 486.0
HKD1_k127_6049064_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 417.0
HKD1_k127_6049064_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 402.0
HKD1_k127_6049064_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
HKD1_k127_6049064_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 262.0
HKD1_k127_6049064_6 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008073 257.0
HKD1_k127_6049064_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000003347 210.0
HKD1_k127_6049064_8 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000005027 135.0
HKD1_k127_6049064_9 Cell division protein FtsQ K03589 - - 0.00000000002178 78.0
HKD1_k127_6062426_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 410.0
HKD1_k127_6062426_1 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000007185 124.0
HKD1_k127_6065284_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 534.0
HKD1_k127_6065284_1 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 373.0
HKD1_k127_6065284_10 - - - - 0.00000000000000000000905 99.0
HKD1_k127_6065284_11 Domain of unknown function (DUF4258) - - - 0.000000002217 63.0
HKD1_k127_6065284_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000001154 261.0
HKD1_k127_6065284_3 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000509 243.0
HKD1_k127_6065284_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001237 228.0
HKD1_k127_6065284_5 - - - - 0.0000000000000000000000000000000000000000000000000000000003669 218.0
HKD1_k127_6065284_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000004914 211.0
HKD1_k127_6065284_7 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000002988 201.0
HKD1_k127_6065284_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000001298 130.0
HKD1_k127_6065284_9 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000009297 109.0
HKD1_k127_6067517_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 405.0
HKD1_k127_6067517_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001664 274.0
HKD1_k127_6067517_10 - - - - 0.00000000000000000000000000000000000000000000002266 175.0
HKD1_k127_6067517_11 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000002829 171.0
HKD1_k127_6067517_12 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000000001642 140.0
HKD1_k127_6067517_13 - - - - 0.0000000000000000000000000000000001234 134.0
HKD1_k127_6067517_14 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000001926 122.0
HKD1_k127_6067517_15 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000000000006532 114.0
HKD1_k127_6067517_16 - - - - 0.000000000000000000000003163 110.0
HKD1_k127_6067517_17 - - - - 0.00000000000000000000001191 106.0
HKD1_k127_6067517_18 Cupin domain - - - 0.0000000000008676 78.0
HKD1_k127_6067517_19 - - - - 0.000000000002906 70.0
HKD1_k127_6067517_2 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002396 250.0
HKD1_k127_6067517_3 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000038 214.0
HKD1_k127_6067517_4 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000000000000000000000000000000000000000005425 219.0
HKD1_k127_6067517_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000002395 193.0
HKD1_k127_6067517_6 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000003526 200.0
HKD1_k127_6067517_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000004484 205.0
HKD1_k127_6067517_8 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000111 194.0
HKD1_k127_6067517_9 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000005328 202.0
HKD1_k127_6071974_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 447.0
HKD1_k127_6071974_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 293.0
HKD1_k127_6071974_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001627 267.0
HKD1_k127_6071974_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
HKD1_k127_6071974_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000005921 179.0
HKD1_k127_6082786_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.43e-219 715.0
HKD1_k127_6082786_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000002058 230.0
HKD1_k127_6082786_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000004141 217.0
HKD1_k127_6082786_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000002853 197.0
HKD1_k127_6082786_4 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000628 192.0
HKD1_k127_6082786_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000004827 123.0
HKD1_k127_6082786_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000001524 99.0
HKD1_k127_6082786_7 Glycoprotease family - - - 0.000000000000001396 85.0
HKD1_k127_6082786_8 Protein of unknown function (DUF465) - - - 0.0001686 48.0
HKD1_k127_6082786_9 PFAM Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0006119 52.0
HKD1_k127_6087340_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 497.0
HKD1_k127_6087340_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 374.0
HKD1_k127_6087340_2 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005199 287.0
HKD1_k127_6087340_3 Peptidase family M23 K21471 - - 0.000001934 57.0
HKD1_k127_6095046_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 595.0
HKD1_k127_6095046_1 FAD binding domain K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 597.0
HKD1_k127_6095046_2 - - - - 0.0000000000000000000000000000000000000000000000000003061 191.0
HKD1_k127_6095046_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000002963 158.0
HKD1_k127_6095046_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000001872 156.0
HKD1_k127_6095046_5 6-phosphogluconolactonase activity - - - 0.000000000000000000000000005284 129.0
HKD1_k127_6110794_0 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 404.0
HKD1_k127_6110794_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 403.0
HKD1_k127_6110794_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001279 214.0
HKD1_k127_6110794_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000002172 218.0
HKD1_k127_6110794_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000003809 128.0
HKD1_k127_6110794_5 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.00000000000000000000007304 113.0
HKD1_k127_6110794_6 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.0000000009279 72.0
HKD1_k127_6110794_7 HEAT repeats K18979 - 1.17.99.6 0.0006419 52.0
HKD1_k127_6110794_8 PFAM phosphatidate cytidylyltransferase - - - 0.0006485 52.0
HKD1_k127_6120506_0 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000008168 174.0
HKD1_k127_6120506_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000001056 105.0
HKD1_k127_6120506_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000955 49.0
HKD1_k127_6127840_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 540.0
HKD1_k127_6127840_1 PFAM aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 410.0
HKD1_k127_6127840_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 386.0
HKD1_k127_6127840_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000008292 239.0
HKD1_k127_6127840_4 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000007652 186.0
HKD1_k127_6127840_5 Hfq protein - - - 0.0000000000000000000000000000003823 126.0
HKD1_k127_6127840_6 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000004597 119.0
HKD1_k127_6127840_7 Glycosyltransferase family 92 - - - 0.000000000000000000008089 99.0
HKD1_k127_6127840_8 Septum formation initiator - - - 0.0002145 49.0
HKD1_k127_6128521_0 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 420.0
HKD1_k127_6138393_0 TonB-dependent Receptor Plug K16092 - - 0.00000000000000000000000000000000000000000000000000002922 208.0
HKD1_k127_6138574_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 610.0
HKD1_k127_6138574_1 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000003904 157.0
HKD1_k127_6138574_2 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.00000000000000001708 88.0
HKD1_k127_6139737_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.001e-217 690.0
HKD1_k127_6139737_1 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 459.0
HKD1_k127_6139737_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
HKD1_k127_6139737_3 racemase activity, acting on amino acids and derivatives K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000368 270.0
HKD1_k127_6139737_4 heme binding K19720 - - 0.00000000000000000000000000000000000242 149.0
HKD1_k127_6139737_5 Dodecin K09165 - - 0.0000000000000000002962 91.0
HKD1_k127_6147529_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 353.0
HKD1_k127_6147529_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 321.0
HKD1_k127_6147529_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000003981 137.0
HKD1_k127_6147529_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002405 91.0
HKD1_k127_6147529_4 Transglycosylase SLT domain K08309 - - 0.00000000001809 78.0
HKD1_k127_6147529_5 zinc-ribbon domain - - - 0.00000000004031 75.0
HKD1_k127_6151703_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 287.0
HKD1_k127_6151703_1 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000002074 208.0
HKD1_k127_6151703_2 Redoxin - - - 0.0000000000000000000000001409 123.0
HKD1_k127_6155873_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 528.0
HKD1_k127_6155873_1 FAD binding domain K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 464.0
HKD1_k127_6155873_2 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 453.0
HKD1_k127_6155873_3 Metal-dependent hydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 434.0
HKD1_k127_6155873_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 368.0
HKD1_k127_6155873_5 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000001667 251.0
HKD1_k127_6155873_6 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.000000000000000000000000000000000000005589 149.0
HKD1_k127_6155873_7 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.00000000000000000000000000000000001409 145.0
HKD1_k127_6155873_8 DinB family - - - 0.00000000000000000000000000000000344 146.0
HKD1_k127_6156173_0 Radical SAM - - - 5.6e-226 708.0
HKD1_k127_6156173_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 388.0
HKD1_k127_6156173_2 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 299.0
HKD1_k127_6156173_3 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003609 280.0
HKD1_k127_6156173_4 receptor K16092 - - 0.00000000000000000006431 104.0
HKD1_k127_6156173_5 lysyltransferase activity K07027 - - 0.00001048 57.0
HKD1_k127_6160143_0 MacB-like periplasmic core domain - - - 8.915e-198 646.0
HKD1_k127_6160143_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 619.0
HKD1_k127_6160143_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 602.0
HKD1_k127_6160143_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 592.0
HKD1_k127_6160143_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 543.0
HKD1_k127_6160143_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000008013 121.0
HKD1_k127_6160143_6 MacB-like periplasmic core domain - - - 0.000000000000000002092 90.0
HKD1_k127_6175554_0 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 325.0
HKD1_k127_6175554_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 294.0
HKD1_k127_6175554_2 Protein of unknown function (DUF962) - - - 0.000000000000007081 75.0
HKD1_k127_6175554_3 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000007464 67.0
HKD1_k127_6194784_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 631.0
HKD1_k127_6194784_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 502.0
HKD1_k127_6194784_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001899 295.0
HKD1_k127_6194784_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007752 285.0
HKD1_k127_6194784_12 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007329 272.0
HKD1_k127_6194784_13 Belongs to the pseudouridine synthase RsuA family K06178,K06182,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000004589 225.0
HKD1_k127_6194784_14 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000001139 226.0
HKD1_k127_6194784_15 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000004635 221.0
HKD1_k127_6194784_16 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000009834 201.0
HKD1_k127_6194784_17 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000146 198.0
HKD1_k127_6194784_18 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000001248 192.0
HKD1_k127_6194784_19 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000002939 179.0
HKD1_k127_6194784_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 502.0
HKD1_k127_6194784_20 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000006442 171.0
HKD1_k127_6194784_21 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000007293 182.0
HKD1_k127_6194784_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000258 171.0
HKD1_k127_6194784_23 Segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000473 171.0
HKD1_k127_6194784_24 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000002917 149.0
HKD1_k127_6194784_25 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000000000002916 147.0
HKD1_k127_6194784_26 Pfam:DUF989 - - - 0.00000000000000000000000000000001155 136.0
HKD1_k127_6194784_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000004034 126.0
HKD1_k127_6194784_28 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.000000000000000000000000001239 128.0
HKD1_k127_6194784_29 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000001155 115.0
HKD1_k127_6194784_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 454.0
HKD1_k127_6194784_30 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000242 98.0
HKD1_k127_6194784_31 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.0000000000000000004809 97.0
HKD1_k127_6194784_32 Domain of unknown function (DUF4126) - - - 0.0000000000000001647 91.0
HKD1_k127_6194784_33 Domain of unknown function (DUF4388) - - - 0.0000000000000005653 91.0
HKD1_k127_6194784_34 - - - - 0.000000000001467 77.0
HKD1_k127_6194784_35 - - - - 0.0000000007789 70.0
HKD1_k127_6194784_36 Heat shock protein DnaJ domain protein - - - 0.0000853 57.0
HKD1_k127_6194784_37 RNA-binding protein containing a PIN domain K06962 - - 0.0001752 49.0
HKD1_k127_6194784_38 lipopolysaccharide transport K09774 - - 0.000243 54.0
HKD1_k127_6194784_4 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 454.0
HKD1_k127_6194784_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 402.0
HKD1_k127_6194784_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 368.0
HKD1_k127_6194784_7 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 367.0
HKD1_k127_6194784_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 325.0
HKD1_k127_6194784_9 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 315.0
HKD1_k127_6196076_0 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000001847 187.0
HKD1_k127_6196076_1 - - - - 0.00000000000000000000000000000005287 142.0
HKD1_k127_6196076_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000001001 111.0
HKD1_k127_6196076_3 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.00003055 57.0
HKD1_k127_6210853_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 471.0
HKD1_k127_6210853_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001243 244.0
HKD1_k127_6210853_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000004883 152.0
HKD1_k127_6210853_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000001913 161.0
HKD1_k127_6210853_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000002382 124.0
HKD1_k127_6210853_5 repeat-containing protein - - - 0.0008612 50.0
HKD1_k127_6211441_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.494e-228 724.0
HKD1_k127_6211441_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.089e-217 705.0
HKD1_k127_6211441_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001561 282.0
HKD1_k127_6211441_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000005325 260.0
HKD1_k127_6211441_12 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000004728 220.0
HKD1_k127_6211441_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000004028 211.0
HKD1_k127_6211441_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000002616 189.0
HKD1_k127_6211441_15 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000001879 193.0
HKD1_k127_6211441_16 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000001003 183.0
HKD1_k127_6211441_17 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001825 188.0
HKD1_k127_6211441_18 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000003529 188.0
HKD1_k127_6211441_19 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000005001 177.0
HKD1_k127_6211441_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 476.0
HKD1_k127_6211441_20 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000003875 148.0
HKD1_k127_6211441_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000002372 147.0
HKD1_k127_6211441_22 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000306 139.0
HKD1_k127_6211441_23 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000001717 142.0
HKD1_k127_6211441_24 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000003315 124.0
HKD1_k127_6211441_25 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000003294 129.0
HKD1_k127_6211441_26 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000004665 124.0
HKD1_k127_6211441_29 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.0000000000000000003385 94.0
HKD1_k127_6211441_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 421.0
HKD1_k127_6211441_30 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000008594 88.0
HKD1_k127_6211441_31 PFAM membrane bound O-acyl transferase MBOAT family protein - - - 0.00000000000004356 85.0
HKD1_k127_6211441_32 Domain of unknown function (DUF374) K09778 - - 0.0000000000001894 84.0
HKD1_k127_6211441_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000007317 81.0
HKD1_k127_6211441_34 Protein of unknown function (DUF1573) - - - 0.000000000006749 78.0
HKD1_k127_6211441_35 TonB C terminal - - - 0.00000000008688 73.0
HKD1_k127_6211441_36 Cell division protein ZapA K09888 - - 0.000000002387 62.0
HKD1_k127_6211441_37 protein conserved in bacteria K09764 - - 0.000000002439 61.0
HKD1_k127_6211441_38 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0006988 54.0
HKD1_k127_6211441_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 355.0
HKD1_k127_6211441_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 352.0
HKD1_k127_6211441_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 342.0
HKD1_k127_6211441_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 349.0
HKD1_k127_6211441_8 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 355.0
HKD1_k127_6211441_9 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001643 299.0
HKD1_k127_6212368_0 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 314.0
HKD1_k127_6212368_1 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
HKD1_k127_6212368_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000004577 64.0
HKD1_k127_6213872_0 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000962 162.0
HKD1_k127_6213872_1 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000002191 155.0
HKD1_k127_6213872_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000001236 86.0
HKD1_k127_6213872_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000007473 67.0
HKD1_k127_6219355_0 Transposase IS200 like - - - 0.00000000000000000000000000000002954 128.0
HKD1_k127_6219355_1 methyltransferase - - - 0.0000000000002832 81.0
HKD1_k127_6220394_0 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000002292 147.0
HKD1_k127_6221827_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 342.0
HKD1_k127_6221827_1 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000002841 171.0
HKD1_k127_6223660_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 317.0
HKD1_k127_6223660_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000004077 216.0
HKD1_k127_6223660_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000007641 204.0
HKD1_k127_6223660_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000001768 104.0
HKD1_k127_6225504_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 2.276e-230 723.0
HKD1_k127_6225504_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000002131 269.0
HKD1_k127_6225504_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000008604 224.0
HKD1_k127_6225504_3 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000005088 211.0
HKD1_k127_6225504_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000001313 196.0
HKD1_k127_6225504_5 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000000000001331 168.0
HKD1_k127_6225504_6 PFAM Response regulator receiver domain K07658 - - 0.00000000000000000000003242 115.0
HKD1_k127_6225504_7 Acylphosphatase K01512 - 3.6.1.7 0.000000000003498 78.0
HKD1_k127_6225504_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000002588 62.0
HKD1_k127_6232586_0 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003495 300.0
HKD1_k127_6232586_1 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.0000000000000000000000000000000000000000008086 168.0
HKD1_k127_6232586_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000009214 155.0
HKD1_k127_6232586_3 methyltransferase activity K15256 - - 0.000000000000000001833 100.0
HKD1_k127_6232586_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000005184 96.0
HKD1_k127_6232586_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000004515 61.0
HKD1_k127_6232586_6 Helix-turn-helix XRE-family like proteins - - - 0.00014 49.0
HKD1_k127_623774_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 362.0
HKD1_k127_623774_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000009813 107.0
HKD1_k127_623774_2 - - - - 0.0004725 51.0
HKD1_k127_623774_3 PBS lyase HEAT-like repeat - - - 0.0004918 50.0
HKD1_k127_6242888_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000594 245.0
HKD1_k127_6242888_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000005456 228.0
HKD1_k127_6242888_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000008909 137.0
HKD1_k127_6242888_3 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000003766 126.0
HKD1_k127_6242888_4 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000008116 75.0
HKD1_k127_6242888_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000008635 67.0
HKD1_k127_6242888_6 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000269 74.0
HKD1_k127_6242888_7 positive regulation of growth rate - - - 0.0000009195 60.0
HKD1_k127_6242888_8 PFAM helix-turn-helix, Fis-type - - - 0.000001563 53.0
HKD1_k127_6248844_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1010.0
HKD1_k127_6248844_1 Alpha/beta hydrolase family - - - 2.025e-210 680.0
HKD1_k127_6248844_2 PFAM Pyrrolo-quinoline quinone K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002414 229.0
HKD1_k127_6248844_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000001209 109.0
HKD1_k127_6248844_4 - - - - 0.000006674 50.0
HKD1_k127_6271837_0 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 473.0
HKD1_k127_6271837_1 Transketolase, thiamine diphosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 399.0
HKD1_k127_6271837_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000003791 258.0
HKD1_k127_6271837_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000009567 233.0
HKD1_k127_6271837_4 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000002598 211.0
HKD1_k127_6271837_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000002149 186.0
HKD1_k127_6271837_6 diguanylate cyclase - - - 0.000000000000000000000000000000000001005 153.0
HKD1_k127_6271837_7 MgtC family K07507 - - 0.00000000000000000000000000001889 134.0
HKD1_k127_6271837_8 Alpha beta hydrolase - - - 0.00000000000000000003794 93.0
HKD1_k127_6281820_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.026e-254 797.0
HKD1_k127_6281820_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000002562 74.0
HKD1_k127_6289619_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 562.0
HKD1_k127_6289619_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 509.0
HKD1_k127_6292849_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1660.0
HKD1_k127_6292849_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 576.0
HKD1_k127_6303050_0 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001513 254.0
HKD1_k127_6303050_1 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
HKD1_k127_6303050_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000006242 182.0
HKD1_k127_6310240_0 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 284.0
HKD1_k127_6310240_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001578 262.0
HKD1_k127_6310240_2 Yip1 domain - - - 0.0001184 53.0
HKD1_k127_6317565_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002177 293.0
HKD1_k127_6317565_1 PFAM Diacylglycerol kinase, catalytic - - - 0.0000000000000000000000001301 113.0
HKD1_k127_6317565_2 VIT family - - - 0.000000000002846 72.0
HKD1_k127_6317565_3 PFAM Penicillinase repressor - - - 0.00000000009615 68.0
HKD1_k127_6317565_4 BlaR1 peptidase M56 - - - 0.000000009534 68.0
HKD1_k127_6321207_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 561.0
HKD1_k127_6321207_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000002021 80.0
HKD1_k127_6327840_0 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000001921 214.0
HKD1_k127_6327840_1 cheY-homologous receiver domain - - - 0.000000000000000000005698 102.0
HKD1_k127_6327840_2 PFAM PKD domain containing protein - - - 0.000000000000004776 89.0
HKD1_k127_6327840_3 - - - - 0.000000009769 67.0
HKD1_k127_6331324_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 548.0
HKD1_k127_6331324_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 293.0
HKD1_k127_6344456_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 602.0
HKD1_k127_6344456_1 - - - - 0.00000000000000000000000000000000000000000000001219 187.0
HKD1_k127_6344456_2 Citrate transporter - - - 0.000000000000000000000000000000009754 142.0
HKD1_k127_6344456_3 Acetyltransferase (GNAT) family - - - 0.0000000000000005002 93.0
HKD1_k127_6344456_4 Recombinase zinc beta ribbon domain K06400 - - 0.000003976 53.0
HKD1_k127_6347974_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 578.0
HKD1_k127_6347974_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000003425 209.0
HKD1_k127_6361731_0 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 430.0
HKD1_k127_6361731_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000001795 252.0
HKD1_k127_6361731_2 RelA SpoT domain protein - - - 0.000000000000000000000000000000000000000000000001 199.0
HKD1_k127_6361731_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000004103 81.0
HKD1_k127_6361731_4 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000004079 67.0
HKD1_k127_6364925_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 328.0
HKD1_k127_6364925_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 333.0
HKD1_k127_6364925_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000001005 151.0
HKD1_k127_6364925_11 YgbB family K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.0000000000000000000000000001234 131.0
HKD1_k127_6364925_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000003186 111.0
HKD1_k127_6364925_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002635 299.0
HKD1_k127_6364925_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001583 252.0
HKD1_k127_6364925_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000001857 190.0
HKD1_k127_6364925_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001921 182.0
HKD1_k127_6364925_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000002862 183.0
HKD1_k127_6364925_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000004983 185.0
HKD1_k127_6364925_8 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000004518 169.0
HKD1_k127_6364925_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000001635 140.0
HKD1_k127_6365567_0 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 315.0
HKD1_k127_6365567_1 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000001238 233.0
HKD1_k127_6365567_2 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000241 217.0
HKD1_k127_6365567_3 alginic acid biosynthetic process - - - 0.00000000000000000000000000003905 126.0
HKD1_k127_6366231_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000671 271.0
HKD1_k127_6366231_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000006634 203.0
HKD1_k127_6366231_2 - K01992,K19341 - - 0.0000000000000000000000000000000000004392 154.0
HKD1_k127_6366231_3 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000004675 124.0
HKD1_k127_6366231_4 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000001633 98.0
HKD1_k127_6366231_5 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000001733 104.0
HKD1_k127_6370162_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 568.0
HKD1_k127_6370162_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 306.0
HKD1_k127_6370162_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000286 263.0
HKD1_k127_6370162_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
HKD1_k127_6370162_4 DoxX - - - 0.00000000000000000000000000000000000000000000000000009575 203.0
HKD1_k127_6370162_5 - - - - 0.000000000000000000000000004272 115.0
HKD1_k127_6370162_6 - - - - 0.0000000000000000000000002407 110.0
HKD1_k127_6370162_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000101 106.0
HKD1_k127_6370162_8 SnoaL-like domain - - - 0.00000000000000000000000632 107.0
HKD1_k127_6370162_9 - - - - 0.0000000002327 69.0
HKD1_k127_6382350_0 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 336.0
HKD1_k127_6382350_1 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 275.0
HKD1_k127_6382350_2 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000001907 154.0
HKD1_k127_6397416_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 5.531e-203 666.0
HKD1_k127_6397416_1 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000221 228.0
HKD1_k127_6397416_2 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000005482 216.0
HKD1_k127_6397416_3 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000001268 159.0
HKD1_k127_6397416_4 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000004165 127.0
HKD1_k127_6404449_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 429.0
HKD1_k127_6404449_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003381 264.0
HKD1_k127_6404449_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
HKD1_k127_6404449_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000003322 188.0
HKD1_k127_6404449_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000071 154.0
HKD1_k127_6404449_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000002897 152.0
HKD1_k127_6404449_6 antibiotic catabolic process K18235 - - 0.000000002583 71.0
HKD1_k127_6404449_7 Cytochrome c7 and related cytochrome c - - - 0.000004217 51.0
HKD1_k127_6437048_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 472.0
HKD1_k127_6437048_1 Universal stress protein - - - 0.00005332 52.0
HKD1_k127_6490827_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 316.0
HKD1_k127_6490827_1 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000001981 189.0
HKD1_k127_6524646_0 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 349.0
HKD1_k127_6524646_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000001492 218.0
HKD1_k127_6567512_0 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 509.0
HKD1_k127_6567512_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 407.0
HKD1_k127_6567512_2 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 351.0
HKD1_k127_6567512_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000004126 209.0
HKD1_k127_6567512_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000006001 165.0
HKD1_k127_6567512_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000001076 141.0
HKD1_k127_6567512_6 Copper resistance protein D K07245 - - 0.000000000000000003006 91.0
HKD1_k127_6567512_7 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000000000000005912 95.0
HKD1_k127_6567512_8 PFAM DoxX K15977 - - 0.000000000007199 78.0
HKD1_k127_6569766_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1441.0
HKD1_k127_6569766_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 442.0
HKD1_k127_6569766_10 MerR, DNA binding - - - 0.0000000000000000000000000000008183 128.0
HKD1_k127_6569766_11 Helix-turn-helix domain - - - 0.000000000000000007317 92.0
HKD1_k127_6569766_12 SnoaL-like domain - - - 0.000000000686 66.0
HKD1_k127_6569766_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 391.0
HKD1_k127_6569766_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
HKD1_k127_6569766_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 375.0
HKD1_k127_6569766_5 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 360.0
HKD1_k127_6569766_6 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001542 303.0
HKD1_k127_6569766_7 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
HKD1_k127_6569766_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000576 230.0
HKD1_k127_6569766_9 cytochrome - - - 0.00000000000000000000000000000000000001178 156.0
HKD1_k127_6572849_0 Dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 406.0
HKD1_k127_6572849_1 - - - - 0.0000000001517 67.0
HKD1_k127_6572849_2 Phospholipase_D-nuclease N-terminal - - - 0.0000000003246 62.0
HKD1_k127_6586934_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002421 264.0
HKD1_k127_6586934_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
HKD1_k127_6586934_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000008356 81.0
HKD1_k127_6627848_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000002288 218.0
HKD1_k127_6627848_1 acetyltransferase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000001333 155.0
HKD1_k127_6627848_2 methyltransferase - - - 0.00005117 55.0
HKD1_k127_6633141_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
HKD1_k127_6633141_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 319.0
HKD1_k127_6633141_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
HKD1_k127_6633141_3 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000000009064 219.0
HKD1_k127_6633141_4 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000005507 97.0
HKD1_k127_6640233_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.41e-198 626.0
HKD1_k127_6640233_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 532.0
HKD1_k127_6640233_2 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 528.0
HKD1_k127_6640233_3 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003444 276.0
HKD1_k127_6640233_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.0000000000000000000000000000000000000000000000001232 181.0
HKD1_k127_6640233_5 Cupin domain - - - 0.0000000000000000000000000000000003491 135.0
HKD1_k127_6640233_6 - - - - 0.000000000000000001558 87.0
HKD1_k127_6640233_7 Protein of unknown function (DUF1203) - - - 0.000000000000000009252 94.0
HKD1_k127_6640233_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000001555 70.0
HKD1_k127_6668092_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 375.0
HKD1_k127_6668092_1 transcriptional regulator - - - 0.0002177 44.0
HKD1_k127_6687766_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 533.0
HKD1_k127_6687766_1 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 396.0
HKD1_k127_6687766_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001014 233.0
HKD1_k127_6687766_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000001128 153.0
HKD1_k127_6687766_4 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000003182 123.0
HKD1_k127_6690886_0 Glycosyl transferase, family 35 K00688,K16153 - 2.4.1.1,2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 440.0
HKD1_k127_6690886_1 PFAM transferase hexapeptide repeat containing protein K00975 - 2.7.7.27 0.000000000000000000004166 98.0
HKD1_k127_6692749_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 546.0
HKD1_k127_6692749_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 391.0
HKD1_k127_6692749_2 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000199 270.0
HKD1_k127_6692749_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000009504 224.0
HKD1_k127_6692749_4 Adenylate cyclase - - - 0.0000000000000006188 92.0
HKD1_k127_6692749_5 FHA domain K07315 - 3.1.3.3 0.0000000002164 74.0
HKD1_k127_6692749_6 radical SAM domain protein - - - 0.00003576 52.0
HKD1_k127_6712183_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 7.083e-299 933.0
HKD1_k127_6712183_1 cytochrome C oxidase K02275 - 1.9.3.1 0.0000000000000000000002344 101.0
HKD1_k127_6712183_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000009257 99.0
HKD1_k127_6712183_3 protein secretion K03116 GO:0008150,GO:0040007 - 0.0000000000003766 71.0
HKD1_k127_6712183_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000009992 56.0
HKD1_k127_6715076_0 Coenzyme A transferase K01027,K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000001011 206.0
HKD1_k127_6715076_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000004666 205.0
HKD1_k127_672305_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 2.947e-284 891.0
HKD1_k127_672305_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001726 281.0
HKD1_k127_672305_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007001 273.0
HKD1_k127_672305_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000006872 207.0
HKD1_k127_673942_0 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.00000000000000000000000000000007887 143.0
HKD1_k127_675575_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 430.0
HKD1_k127_675575_1 abc transporter atp-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 442.0
HKD1_k127_675575_10 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000002562 117.0
HKD1_k127_675575_11 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.00000000000000000000001366 102.0
HKD1_k127_675575_12 to the N-terminal domain of Lon protease K07157 - - 0.000000000000000000000076 108.0
HKD1_k127_675575_13 dead DEAH box helicase K03724 - - 0.0005682 49.0
HKD1_k127_675575_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 386.0
HKD1_k127_675575_3 Probable molybdopterin binding domain K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 322.0
HKD1_k127_675575_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000004702 252.0
HKD1_k127_675575_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000006549 168.0
HKD1_k127_675575_6 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000008933 126.0
HKD1_k127_675575_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000001026 128.0
HKD1_k127_675575_8 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000001767 119.0
HKD1_k127_675575_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000003015 124.0
HKD1_k127_6764291_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 616.0
HKD1_k127_6764291_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 539.0
HKD1_k127_6764291_2 - - - - 0.00000000000000000000000000000000000002728 149.0
HKD1_k127_6766493_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.822e-265 827.0
HKD1_k127_6766493_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 369.0
HKD1_k127_6766493_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000001958 194.0
HKD1_k127_6766493_3 FtsX-like permease family K09808 - - 0.0000000000000000000000000000731 122.0
HKD1_k127_6774303_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 463.0
HKD1_k127_6774303_1 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000121 108.0
HKD1_k127_6774303_2 Parallel beta-helix repeats K12287 - - 0.00000000000000000000001765 114.0
HKD1_k127_6774303_3 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00001587 49.0
HKD1_k127_6812457_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000001378 154.0
HKD1_k127_6812457_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000001767 138.0
HKD1_k127_6812457_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.00000000000000000000000000003078 133.0
HKD1_k127_6812457_3 PFAM Thioesterase superfamily K07107 - - 0.000000000000001266 91.0
HKD1_k127_6818530_0 PFAM oxidoreductase domain protein K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
HKD1_k127_6818530_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 332.0
HKD1_k127_6818530_2 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 265.0
HKD1_k127_6818530_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00006046 46.0
HKD1_k127_6822114_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 518.0
HKD1_k127_6822114_1 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002115 271.0
HKD1_k127_690446_0 Hep Hag repeat protein - - - 0.000000000002269 80.0
HKD1_k127_690446_1 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000006201 51.0
HKD1_k127_690446_2 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00005395 56.0
HKD1_k127_6908985_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.061e-250 786.0
HKD1_k127_6908985_1 DinB family - - - 0.0000000000000000000000000000000000000000009139 166.0
HKD1_k127_6908985_2 - - - - 0.0000000000000000000000000004506 124.0
HKD1_k127_6932335_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000143 278.0
HKD1_k127_6932335_1 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000001343 183.0
HKD1_k127_6932335_2 PFAM TonB-dependent Receptor Plug - - - 0.00002144 51.0
HKD1_k127_7012124_0 oxidoreductase activity - - - 0.0000000000000000000000000001694 133.0
HKD1_k127_7019769_0 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 475.0
HKD1_k127_7019769_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000007534 134.0
HKD1_k127_7019769_2 Belongs to the BI1 family K06890,K19416 - - 0.0006373 44.0
HKD1_k127_7047112_0 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000002741 213.0
HKD1_k127_7047112_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000001743 220.0
HKD1_k127_7049477_0 Prokaryotic cytochrome b561 - - - 0.0 1116.0
HKD1_k127_7049477_1 formate dehydrogenase - - - 1.817e-223 714.0
HKD1_k127_7049477_10 protein histidine kinase activity K06375 - - 0.00000000000000000000003602 107.0
HKD1_k127_7049477_11 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000005088 102.0
HKD1_k127_7049477_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000001201 98.0
HKD1_k127_7049477_13 Belongs to the universal stress protein A family - - - 0.000000000000377 80.0
HKD1_k127_7049477_14 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000109 51.0
HKD1_k127_7049477_16 TIGRFAM DNA binding domain - - - 0.00007327 51.0
HKD1_k127_7049477_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 594.0
HKD1_k127_7049477_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 608.0
HKD1_k127_7049477_4 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 550.0
HKD1_k127_7049477_5 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 509.0
HKD1_k127_7049477_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
HKD1_k127_7049477_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 357.0
HKD1_k127_7049477_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000004489 242.0
HKD1_k127_7049477_9 PFAM Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000001697 146.0
HKD1_k127_7055058_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.521e-218 692.0
HKD1_k127_7055058_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 497.0
HKD1_k127_7055058_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000003924 78.0
HKD1_k127_7055058_12 Glycosyl transferase family 21 - - - 0.00000006261 64.0
HKD1_k127_7055058_2 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 460.0
HKD1_k127_7055058_3 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 412.0
HKD1_k127_7055058_4 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 366.0
HKD1_k127_7055058_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 327.0
HKD1_k127_7055058_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000002665 210.0
HKD1_k127_7055058_7 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000000000000000007628 165.0
HKD1_k127_7055058_8 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000002206 168.0
HKD1_k127_7055058_9 cellulose binding - - - 0.000000000000000000000005395 109.0
HKD1_k127_7059651_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 8.78e-307 960.0
HKD1_k127_7059651_1 formate dehydrogenase K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 328.0
HKD1_k127_7059651_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000004145 262.0
HKD1_k127_7059651_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
HKD1_k127_7059651_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000003777 228.0
HKD1_k127_7059651_5 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000006769 165.0
HKD1_k127_7059651_6 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000008962 131.0
HKD1_k127_7059651_7 phosphorelay signal transduction system - - - 0.00000000000000000000288 97.0
HKD1_k127_7059651_8 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000006309 88.0
HKD1_k127_7059651_9 oxidoreductase activity - - - 0.000000000007401 78.0
HKD1_k127_7060140_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 333.0
HKD1_k127_7060140_1 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000001502 216.0
HKD1_k127_7060140_2 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000156 106.0
HKD1_k127_7060140_3 Sodium:solute symporter family K03307 - - 0.00000000000000000002122 108.0
HKD1_k127_7060140_4 - - - - 0.00000000000000279 89.0
HKD1_k127_7062384_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001454 238.0
HKD1_k127_7062384_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000006457 247.0
HKD1_k127_7062384_2 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.0000000000000000000000000000000000000000000000000000000004138 226.0
HKD1_k127_7062384_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000001069 203.0
HKD1_k127_7062384_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000003166 209.0
HKD1_k127_7062384_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000001008 130.0
HKD1_k127_7076920_0 Voltage gated chloride channel K03281 - - 1.215e-223 709.0
HKD1_k127_7076920_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 627.0
HKD1_k127_7076920_10 Metallo-beta-lactamase superfamily - - - 0.000000000001198 79.0
HKD1_k127_7076920_11 Bacterial membrane protein YfhO - - - 0.00000000003024 77.0
HKD1_k127_7076920_12 polysaccharide biosynthetic process - - - 0.000002515 61.0
HKD1_k127_7076920_2 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 549.0
HKD1_k127_7076920_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 460.0
HKD1_k127_7076920_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 389.0
HKD1_k127_7076920_5 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000002323 218.0
HKD1_k127_7076920_6 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000000002837 175.0
HKD1_k127_7076920_7 peptidase C26 K07010 - - 0.0000000000000000000000000000000002688 152.0
HKD1_k127_7076920_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000004687 126.0
HKD1_k127_7076920_9 cheY-homologous receiver domain - - - 0.000000000000000000000005684 105.0
HKD1_k127_7079888_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 326.0
HKD1_k127_7088495_0 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 419.0
HKD1_k127_7088495_1 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000003815 206.0
HKD1_k127_7088495_2 ABC-type sulfate transport system permease component K02046 - - 0.00000000000000000000000000000000000000000003168 184.0
HKD1_k127_7088495_3 cheY-homologous receiver domain - - - 0.000000000000000000000004221 108.0
HKD1_k127_7088495_4 outer membrane cobalamin receptor K02014,K16092 - - 0.000000007344 64.0
HKD1_k127_7093149_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 476.0
HKD1_k127_7093149_1 Phage integrase, N-terminal SAM-like domain K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000008029 231.0
HKD1_k127_7093149_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000001261 65.0
HKD1_k127_7112728_0 AAA ATPase domain - - - 2.131e-213 688.0
HKD1_k127_7112728_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 326.0
HKD1_k127_7112728_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000004599 196.0
HKD1_k127_7112728_3 PFAM GGDEF domain containing protein - - - 0.0009042 52.0
HKD1_k127_7116696_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5e-231 737.0
HKD1_k127_7116696_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 338.0
HKD1_k127_7116696_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000004097 91.0
HKD1_k127_7116696_3 Pilus assembly protein, PilO K02664 - - 0.0000000000000000006917 94.0
HKD1_k127_7116696_4 HI0933-like protein K07007 - - 0.000000000000001242 76.0
HKD1_k127_7116696_5 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000001106 80.0
HKD1_k127_7129201_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.286e-221 706.0
HKD1_k127_7129201_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
HKD1_k127_7129201_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000001477 178.0
HKD1_k127_7129201_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000006359 173.0
HKD1_k127_7129201_5 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000001825 160.0
HKD1_k127_7129201_6 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000003575 154.0
HKD1_k127_7129201_7 Signal Transduction Histidine Kinase - - - 0.000000000000000000000000008971 123.0
HKD1_k127_7129201_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000001695 87.0
HKD1_k127_7129201_9 COG3794 Plastocyanin - - - 0.0000000004778 65.0
HKD1_k127_7131102_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.097e-255 809.0
HKD1_k127_7131102_1 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000000000000000000001491 226.0
HKD1_k127_7131102_2 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000004168 192.0
HKD1_k127_7131102_3 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000004224 204.0
HKD1_k127_7131102_4 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000004531 137.0
HKD1_k127_7131102_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000006966 80.0
HKD1_k127_7147787_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 613.0
HKD1_k127_7147787_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 494.0
HKD1_k127_7147787_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000002083 162.0
HKD1_k127_7147787_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000002149 149.0
HKD1_k127_7147787_4 domain, Protein - - - 0.00000000000000000000000002801 123.0
HKD1_k127_7147787_5 cheY-homologous receiver domain K07657 - - 0.000000000000000004454 94.0
HKD1_k127_7147787_6 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000009246 89.0
HKD1_k127_7154492_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 510.0
HKD1_k127_7154492_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 340.0
HKD1_k127_7154492_2 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004285 282.0
HKD1_k127_7154492_3 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000183 196.0
HKD1_k127_7154492_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000005708 192.0
HKD1_k127_7154492_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000009992 158.0
HKD1_k127_7154492_6 von Willebrand factor, type A K07114 - - 0.0000000000000000002037 104.0
HKD1_k127_7154492_7 Oxygen tolerance - - - 0.000000000000000001311 101.0
HKD1_k127_7154492_8 Thioredoxin-like - - - 0.0000004852 53.0
HKD1_k127_7154492_9 Tetratricopeptide repeat K07114 - - 0.0001418 55.0
HKD1_k127_7169016_0 Amino acid adenylation domain - - - 0.0 1189.0
HKD1_k127_7169016_1 Amino acid adenylation domain - - - 1.047e-241 807.0
HKD1_k127_7169016_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008084 304.0
HKD1_k127_7169016_11 non-ribosomal peptide synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000014 286.0
HKD1_k127_7169016_12 CMP-N-acetylneuraminic acid synthetase K00983 - 2.7.7.43 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
HKD1_k127_7169016_13 transferase activity, transferring glycosyl groups K07011 - - 0.0000000000000000000000000000000000000000000000000000004236 220.0
HKD1_k127_7169016_14 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000004505 167.0
HKD1_k127_7169016_15 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000002073 156.0
HKD1_k127_7169016_16 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000003195 159.0
HKD1_k127_7169016_17 polysaccharide deacetylase - - - 0.00000000000000000000001673 116.0
HKD1_k127_7169016_18 Glycosyl transferase 4-like domain - - - 0.00000000000000000214 100.0
HKD1_k127_7169016_19 polysaccharide deacetylase - - - 0.0000000000002613 83.0
HKD1_k127_7169016_2 Non-ribosomal peptide synthetase modules and related proteins - - - 4.376e-221 739.0
HKD1_k127_7169016_20 Glycosyltransferase like family 2 - - - 0.000001532 60.0
HKD1_k127_7169016_3 UDP-N-acetylglucosamine 2-epimerase K08068,K18429 - 3.2.1.183,3.2.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 522.0
HKD1_k127_7169016_4 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 532.0
HKD1_k127_7169016_5 PFAM N-acetylneuraminic acid synthase, N-terminal K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 413.0
HKD1_k127_7169016_6 non-ribosomal peptide synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 398.0
HKD1_k127_7169016_7 TIGRFAM Amino acid adenylation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 380.0
HKD1_k127_7169016_8 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 347.0
HKD1_k127_7169016_9 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 350.0
HKD1_k127_7174193_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 379.0
HKD1_k127_7174193_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 306.0
HKD1_k127_7174193_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000002471 241.0
HKD1_k127_7174193_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000007637 196.0
HKD1_k127_7174193_4 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000001389 190.0
HKD1_k127_7174193_5 NUDIX domain - - - 0.00000000000000000000000000000000349 136.0
HKD1_k127_7174193_6 Sporulation related domain - - - 0.0007889 49.0
HKD1_k127_7179379_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 619.0
HKD1_k127_7179379_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
HKD1_k127_7179379_2 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000005628 122.0
HKD1_k127_7179379_3 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000001025 65.0
HKD1_k127_7204258_0 Putative adhesin - - - 0.0000006302 62.0
HKD1_k127_7204258_1 Putative adhesin - - - 0.000001917 61.0
HKD1_k127_7216079_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 418.0
HKD1_k127_7216079_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 362.0
HKD1_k127_7216079_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 304.0
HKD1_k127_7216079_3 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000007385 259.0
HKD1_k127_7216079_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000001066 169.0
HKD1_k127_7216079_5 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000002297 148.0
HKD1_k127_7216079_6 Glycosyltransferase family 87 - - - 0.000000000000000000000000003596 126.0
HKD1_k127_7235265_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 497.0
HKD1_k127_7235265_1 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000003697 222.0
HKD1_k127_7239008_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.178e-290 919.0
HKD1_k127_7239008_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002134 270.0
HKD1_k127_7239008_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000005833 228.0
HKD1_k127_7239008_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000002843 214.0
HKD1_k127_7239008_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000006057 133.0
HKD1_k127_7239008_5 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000000000008875 98.0
HKD1_k127_7239008_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000008822 82.0
HKD1_k127_7240804_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1082.0
HKD1_k127_7240804_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000005057 254.0
HKD1_k127_7240804_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000005232 255.0
HKD1_k127_7240804_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000003593 231.0
HKD1_k127_7240804_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000005003 158.0
HKD1_k127_7245181_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 580.0
HKD1_k127_7245181_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 483.0
HKD1_k127_7245181_10 Putative MetA-pathway of phenol degradation - - - 0.00009893 55.0
HKD1_k127_7245181_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 442.0
HKD1_k127_7245181_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 464.0
HKD1_k127_7245181_4 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 424.0
HKD1_k127_7245181_5 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 374.0
HKD1_k127_7245181_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 311.0
HKD1_k127_7245181_7 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000005827 235.0
HKD1_k127_7245181_8 - - - - 0.00000000000002539 83.0
HKD1_k127_7245181_9 S4 RNA-binding domain K04762 - - 0.00000000003632 76.0
HKD1_k127_725623_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 430.0
HKD1_k127_725623_1 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000408 227.0
HKD1_k127_725623_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000001822 198.0
HKD1_k127_725623_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000001904 81.0
HKD1_k127_725623_4 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000001837 71.0
HKD1_k127_7259358_0 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 555.0
HKD1_k127_7259358_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
HKD1_k127_7259358_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 376.0
HKD1_k127_7259358_3 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000366 191.0
HKD1_k127_7275910_0 metallopeptidase activity - - - 5.958e-258 814.0
HKD1_k127_7275910_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 415.0
HKD1_k127_7275910_2 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 379.0
HKD1_k127_7275910_3 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000007193 132.0
HKD1_k127_7280627_0 KR domain - - - 0.000000000000000000000000000000000000000009485 160.0
HKD1_k127_7280627_1 phosphorelay signal transduction system K07669 - - 0.000000000000256 77.0
HKD1_k127_7282799_0 Belongs to the glycosyl hydrolase 2 family - - - 1.24e-268 856.0
HKD1_k127_7282799_1 Heat shock 70 kDa protein K04043 - - 8.315e-230 726.0
HKD1_k127_7282799_10 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000003968 208.0
HKD1_k127_7282799_11 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000008595 184.0
HKD1_k127_7282799_12 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000002659 178.0
HKD1_k127_7282799_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000002303 152.0
HKD1_k127_7282799_14 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000008353 136.0
HKD1_k127_7282799_15 Rossmann-like domain - - - 0.0000000000000000000000000000004256 132.0
HKD1_k127_7282799_16 - - - - 0.000000000000000000000000002829 113.0
HKD1_k127_7282799_17 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000002039 111.0
HKD1_k127_7282799_18 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.0001729 53.0
HKD1_k127_7282799_2 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 466.0
HKD1_k127_7282799_3 adenylosuccinate lyase K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 466.0
HKD1_k127_7282799_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 387.0
HKD1_k127_7282799_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 381.0
HKD1_k127_7282799_6 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 360.0
HKD1_k127_7282799_7 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007806 273.0
HKD1_k127_7282799_8 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000001121 224.0
HKD1_k127_7282799_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000002109 230.0
HKD1_k127_7289751_0 PFAM NHL repeat containing protein - - - 9.891e-252 816.0
HKD1_k127_7289751_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
HKD1_k127_7289751_2 collagen metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000003996 248.0
HKD1_k127_7289751_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000001417 222.0
HKD1_k127_7289751_4 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000151 111.0
HKD1_k127_7289751_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000002115 96.0
HKD1_k127_7289751_6 SNARE associated Golgi protein K03975 - - 0.000000004119 58.0
HKD1_k127_7297970_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.502e-308 957.0
HKD1_k127_7297970_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 629.0
HKD1_k127_7297970_10 COGs COG0110 Acetyltransferase (isoleucine patch superfamily) K00633 - 2.3.1.18 0.000000000000000000000000000000000000000000000000000000000001686 232.0
HKD1_k127_7297970_11 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000002114 215.0
HKD1_k127_7297970_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000003122 214.0
HKD1_k127_7297970_13 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000002246 181.0
HKD1_k127_7297970_14 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000001295 186.0
HKD1_k127_7297970_15 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000001676 143.0
HKD1_k127_7297970_16 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.00000001368 67.0
HKD1_k127_7297970_2 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 371.0
HKD1_k127_7297970_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 338.0
HKD1_k127_7297970_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 340.0
HKD1_k127_7297970_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 310.0
HKD1_k127_7297970_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002483 284.0
HKD1_k127_7297970_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K01498,K11752 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000001127 288.0
HKD1_k127_7297970_8 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009817 269.0
HKD1_k127_7297970_9 ThiF family K03148,K21029 - 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000001198 253.0
HKD1_k127_7301456_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000005989 254.0
HKD1_k127_7301456_1 Tetratricopeptide repeat - - - 0.000000000009022 80.0
HKD1_k127_7307359_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 440.0
HKD1_k127_7307359_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001721 271.0
HKD1_k127_7307359_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000007123 108.0
HKD1_k127_7307359_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000009374 68.0
HKD1_k127_7307359_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000001037 63.0
HKD1_k127_7308733_0 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 336.0
HKD1_k127_7309275_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 505.0
HKD1_k127_7328753_0 Protein kinase domain K12132 - 2.7.11.1 4.412e-198 639.0
HKD1_k127_7328753_1 RNB K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 559.0
HKD1_k127_7328753_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 330.0
HKD1_k127_7328753_3 helix_turn_helix, mercury resistance - - - 0.0000000000001161 76.0
HKD1_k127_7344914_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.187e-230 736.0
HKD1_k127_7344914_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 321.0
HKD1_k127_7344914_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003571 284.0
HKD1_k127_7344914_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 289.0
HKD1_k127_7344914_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
HKD1_k127_7344914_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000002034 218.0
HKD1_k127_7344914_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001869 131.0
HKD1_k127_7344914_7 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000006244 125.0
HKD1_k127_7344914_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000008597 128.0
HKD1_k127_7344914_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000006892 71.0
HKD1_k127_7388288_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7e-303 942.0
HKD1_k127_7388288_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002555 222.0
HKD1_k127_7388288_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001458 225.0
HKD1_k127_7388288_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000001566 144.0
HKD1_k127_7422587_0 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 460.0
HKD1_k127_7422587_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 265.0
HKD1_k127_7422587_10 - - - - 0.0000002641 62.0
HKD1_k127_7422587_11 - - - - 0.000001962 59.0
HKD1_k127_7422587_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000004482 152.0
HKD1_k127_7422587_3 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000453 134.0
HKD1_k127_7422587_4 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000001153 136.0
HKD1_k127_7422587_5 - - - - 0.0000000000000000000000000000002972 143.0
HKD1_k127_7422587_6 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000004435 125.0
HKD1_k127_7422587_7 beta-lactamase activity K07126 - - 0.0000000000000000000000000000006729 138.0
HKD1_k127_7422587_8 DinB superfamily - - - 0.00000000000000000000000000002008 124.0
HKD1_k127_7422587_9 DNA-templated transcription, termination K02600,K02945 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000006101 72.0
HKD1_k127_7429704_0 phosphoesterase, PA-phosphatase related - - - 1.144e-194 629.0
HKD1_k127_7429704_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000009601 175.0
HKD1_k127_7429704_3 ketosteroid isomerase - - - 0.000376 50.0
HKD1_k127_7441809_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 379.0
HKD1_k127_7458455_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 517.0
HKD1_k127_7458455_1 PFAM Amino acid K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 329.0
HKD1_k127_7459401_0 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 577.0
HKD1_k127_7477964_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
HKD1_k127_7477964_1 TonB-dependent receptor K16092 - - 0.00000000009656 67.0
HKD1_k127_7494849_0 Involved in the tonB-independent uptake of proteins - - - 6.949e-204 664.0
HKD1_k127_7494849_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000001764 148.0
HKD1_k127_7501067_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 250.0
HKD1_k127_7501067_1 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000386 115.0
HKD1_k127_7501067_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 0.000000000000008693 87.0
HKD1_k127_7510902_0 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000008848 171.0
HKD1_k127_751624_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 502.0
HKD1_k127_751624_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 488.0
HKD1_k127_751624_10 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000001045 108.0
HKD1_k127_751624_11 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000001364 85.0
HKD1_k127_751624_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 472.0
HKD1_k127_751624_3 saccharopine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 358.0
HKD1_k127_751624_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000001409 268.0
HKD1_k127_751624_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000002597 229.0
HKD1_k127_751624_6 Cupin 2, conserved barrel domain protein K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000001708 216.0
HKD1_k127_751624_7 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000006485 205.0
HKD1_k127_751624_8 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000008115 145.0
HKD1_k127_7533020_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1441.0
HKD1_k127_7533020_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 483.0
HKD1_k127_7533020_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 413.0
HKD1_k127_7533020_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001461 292.0
HKD1_k127_7533020_4 peptidyl-tyrosine sulfation - - - 0.00000000000000007339 91.0
HKD1_k127_7533020_5 cheY-homologous receiver domain - - - 0.0009325 46.0
HKD1_k127_7537403_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 502.0
HKD1_k127_7537403_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 467.0
HKD1_k127_7537403_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007092 272.0
HKD1_k127_7537403_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001733 258.0
HKD1_k127_7537403_4 Virulence factor BrkB K07058 - - 0.00000000000000001074 98.0
HKD1_k127_7537403_5 Putative prokaryotic signal transducing protein - - - 0.0002089 49.0
HKD1_k127_7579834_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 420.0
HKD1_k127_7584390_0 - - - - 0.0000000000000000000000000000000000001251 160.0
HKD1_k127_7584390_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000114 113.0
HKD1_k127_7584390_2 esterase - - - 0.000000000000000000000002202 111.0
HKD1_k127_7584390_3 - - - - 0.0000003293 58.0
HKD1_k127_7597097_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.524e-241 771.0
HKD1_k127_7597097_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 575.0
HKD1_k127_7597097_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 451.0
HKD1_k127_7597097_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 366.0
HKD1_k127_7597097_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000004504 203.0
HKD1_k127_7643843_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 364.0
HKD1_k127_7643843_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 311.0
HKD1_k127_7643843_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 273.0
HKD1_k127_7643843_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000001227 236.0
HKD1_k127_7643843_4 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000003871 134.0
HKD1_k127_7643843_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000264 125.0
HKD1_k127_765626_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 410.0
HKD1_k127_765626_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000002952 81.0
HKD1_k127_765626_2 lactoylglutathione lyase activity - - - 0.0000003785 63.0
HKD1_k127_7660935_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 479.0
HKD1_k127_7660935_1 DNA-binding transcription factor activity - - - 0.000000000000000000000001095 115.0
HKD1_k127_7660935_2 Outer membrane efflux protein - - - 0.00000000003771 75.0
HKD1_k127_7661002_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1482.0
HKD1_k127_7661002_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 374.0
HKD1_k127_7661002_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 345.0
HKD1_k127_7661002_3 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003107 279.0
HKD1_k127_7661002_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000003474 243.0
HKD1_k127_7661002_5 cellulase activity - - - 0.0000001844 59.0
HKD1_k127_766392_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
HKD1_k127_7713149_0 4Fe-4S single cluster domain K06937 - - 1.868e-222 701.0
HKD1_k127_7713149_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000008786 221.0
HKD1_k127_7713149_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003521 188.0
HKD1_k127_7733272_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 474.0
HKD1_k127_7733272_1 Protein of unknown function (DUF962) - - - 0.00000000000000000000003024 116.0
HKD1_k127_7733272_2 cysteine dioxygenase type I - - - 0.000131 49.0
HKD1_k127_7818936_0 ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 312.0
HKD1_k127_7818936_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007747 278.0
HKD1_k127_7818936_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000001171 183.0
HKD1_k127_7818936_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000005345 168.0
HKD1_k127_7818936_4 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000001237 104.0
HKD1_k127_7851770_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 569.0
HKD1_k127_7851770_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 417.0
HKD1_k127_7851770_10 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000153 174.0
HKD1_k127_7851770_11 Ribosomal protein S19 K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000001966 149.0
HKD1_k127_7851770_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001976 150.0
HKD1_k127_7851770_13 Ribosomal protein L15 K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000005469 164.0
HKD1_k127_7851770_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000001637 152.0
HKD1_k127_7851770_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000004037 120.0
HKD1_k127_7851770_16 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000001727 119.0
HKD1_k127_7851770_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000361 113.0
HKD1_k127_7851770_18 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000002197 109.0
HKD1_k127_7851770_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000003689 100.0
HKD1_k127_7851770_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 287.0
HKD1_k127_7851770_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000006624 85.0
HKD1_k127_7851770_21 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007088 79.0
HKD1_k127_7851770_22 Ribosomal protein L30p/L7e K02907 - - 0.000000000000008187 79.0
HKD1_k127_7851770_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00003191 53.0
HKD1_k127_7851770_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
HKD1_k127_7851770_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007081 258.0
HKD1_k127_7851770_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
HKD1_k127_7851770_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000112 214.0
HKD1_k127_7851770_7 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002407 209.0
HKD1_k127_7851770_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000005694 173.0
HKD1_k127_7851770_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000002852 169.0
HKD1_k127_788724_0 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.000000000000000000000000000000000000000001336 170.0
HKD1_k127_788724_1 beta-lactamase - - - 0.0000000000000000000000000000000000000001585 173.0
HKD1_k127_788724_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000004981 127.0
HKD1_k127_788724_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01945 - 6.3.2.6,6.3.4.13 0.0000002278 55.0
HKD1_k127_7916703_0 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 346.0
HKD1_k127_7916703_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 316.0
HKD1_k127_7916703_2 Hep Hag repeat protein K21449 - - 0.00000000000000000000000000000000000000000000000000004685 212.0
HKD1_k127_7916703_3 - - - - 0.0000000000000000000000000000000000000000000008462 188.0
HKD1_k127_7916703_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000002551 103.0
HKD1_k127_7916703_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000001318 55.0
HKD1_k127_807889_0 Large exoproteins involved in heme utilization or adhesion - - - 0.0000000000000000000000009432 120.0
HKD1_k127_807889_1 Subtilase family - - - 0.000000000001661 80.0
HKD1_k127_809736_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 444.0
HKD1_k127_809736_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 414.0
HKD1_k127_809736_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000331 114.0
HKD1_k127_874621_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 583.0
HKD1_k127_874621_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 472.0
HKD1_k127_874621_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 398.0
HKD1_k127_874621_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 367.0
HKD1_k127_874621_4 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000003288 159.0
HKD1_k127_874621_5 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000007735 130.0
HKD1_k127_874621_6 - - - - 0.00000000000000000000000003701 123.0
HKD1_k127_874621_7 - - - - 0.000005703 54.0
HKD1_k127_880095_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 8.834e-276 865.0
HKD1_k127_880095_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.781e-266 837.0
HKD1_k127_880095_2 Protein kinase domain K12132 - 2.7.11.1 2.259e-249 799.0
HKD1_k127_880095_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.075e-215 698.0
HKD1_k127_880095_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 631.0
HKD1_k127_880095_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 594.0
HKD1_k127_880095_6 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 429.0
HKD1_k127_880095_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 423.0
HKD1_k127_880095_8 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 421.0
HKD1_k127_880095_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
HKD1_k127_88853_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.001e-214 673.0
HKD1_k127_88853_1 Malate synthase K01638 - 2.3.3.9 7.608e-207 658.0
HKD1_k127_88853_2 Pfam:DUF955 K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 444.0
HKD1_k127_88853_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000002108 186.0
HKD1_k127_893185_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
HKD1_k127_893185_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000003484 243.0
HKD1_k127_893185_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000002295 212.0
HKD1_k127_893185_3 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000005982 186.0
HKD1_k127_893185_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000001621 109.0
HKD1_k127_893185_5 Belongs to the UPF0312 family - - - 0.000003595 56.0
HKD1_k127_902383_0 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 609.0
HKD1_k127_902383_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 509.0
HKD1_k127_902383_2 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000005731 115.0
HKD1_k127_919765_0 Glycosyl hydrolase family 1 - - - 1.534e-226 708.0
HKD1_k127_919765_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 428.0
HKD1_k127_919765_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000002339 179.0
HKD1_k127_94705_0 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000007188 138.0
HKD1_k127_94705_1 Sigma-70 region 2 K03088 - - 0.000000000000000000008885 104.0
HKD1_k127_94705_2 Heavy-metal resistance - - - 0.0003895 53.0
HKD1_k127_97665_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.234e-241 757.0
HKD1_k127_97665_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
HKD1_k127_97665_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 445.0
HKD1_k127_97665_3 sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000003172 234.0
HKD1_k127_97665_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000001363 139.0
HKD1_k127_97665_5 PFAM glycosyl transferase group 1 - - - 0.00000000002106 76.0
HKD1_k127_97665_6 O-Antigen ligase - - - 0.0000013 61.0
HKD1_k127_985050_0 Peptidase family M1 domain K01992 - - 0.000000000002061 80.0
HKD1_k127_98513_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 469.0
HKD1_k127_98513_1 Damage-inducible protein DinB - - - 0.00000000000000000000000000000000000000000000000003081 184.0
HKD1_k127_98513_2 Sulfite exporter TauE/SafE K07090 - - 0.000001382 61.0