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Overview

ID MAG01729
Name HKD1_bin.47
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus RBG-13-68-16
Species
Assembly information
Completeness (%) 51.78
Contamination (%) 0.1
GC content (%) 68.0
N50 (bp) 4,402
Genome size (bp) 1,247,376

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1148

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_100896_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000003343 132.0
HKD1_k127_100896_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000006955 113.0
HKD1_k127_100896_2 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000001949 100.0
HKD1_k127_100896_3 RES - - - 0.0002654 48.0
HKD1_k127_1026567_0 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 485.0
HKD1_k127_1045906_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000006666 204.0
HKD1_k127_1045906_1 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000003027 170.0
HKD1_k127_1045906_2 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000005615 126.0
HKD1_k127_1046049_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 329.0
HKD1_k127_1046049_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000006607 141.0
HKD1_k127_1066766_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000003493 263.0
HKD1_k127_1066766_1 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000006797 246.0
HKD1_k127_1066766_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000001313 168.0
HKD1_k127_1066766_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000002648 121.0
HKD1_k127_1066766_4 Domain of unknown function (DUF4440) - - - 0.000000000428 68.0
HKD1_k127_1066766_5 Amino-transferase class IV K00826 - 2.6.1.42 0.00004319 48.0
HKD1_k127_1080781_0 Peptidase family M3 K01284,K01414 - 3.4.15.5,3.4.24.70 6.164e-266 841.0
HKD1_k127_1080781_1 Zinc-binding dehydrogenase K12957 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
HKD1_k127_1080781_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000001059 106.0
HKD1_k127_1080781_3 Putative adhesin - - - 0.000000000000007441 87.0
HKD1_k127_1080781_4 Amidase K01426 - 3.5.1.4 0.000000000000325 70.0
HKD1_k127_1080781_5 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000006884 49.0
HKD1_k127_1083625_0 hydrogenase large subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 309.0
HKD1_k127_1083625_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000001477 210.0
HKD1_k127_1102199_0 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000001612 115.0
HKD1_k127_1102199_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000003301 85.0
HKD1_k127_11080_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 436.0
HKD1_k127_11080_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 429.0
HKD1_k127_11080_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
HKD1_k127_11080_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000356 252.0
HKD1_k127_11080_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 0.00000006473 55.0
HKD1_k127_1123477_0 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000006915 168.0
HKD1_k127_1123477_1 TonB dependent receptor K16087 - - 0.00000000116 69.0
HKD1_k127_1136474_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 420.0
HKD1_k127_1136474_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000313 258.0
HKD1_k127_1136474_2 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000073 193.0
HKD1_k127_1136474_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000004963 166.0
HKD1_k127_1137516_0 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 486.0
HKD1_k127_1145953_0 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 298.0
HKD1_k127_1145953_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000001224 214.0
HKD1_k127_1145953_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000131 59.0
HKD1_k127_1149959_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001327 268.0
HKD1_k127_1149959_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000001562 218.0
HKD1_k127_1149959_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000003595 200.0
HKD1_k127_1149959_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000001478 183.0
HKD1_k127_1149959_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000004847 164.0
HKD1_k127_1149959_5 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000000000004354 166.0
HKD1_k127_1149959_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000002287 154.0
HKD1_k127_1149959_7 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000006576 122.0
HKD1_k127_1149959_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000006209 81.0
HKD1_k127_1149959_9 general secretion pathway protein - - - 0.0000000000000006363 88.0
HKD1_k127_1159882_0 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000001072 180.0
HKD1_k127_1159882_1 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000000000000002822 106.0
HKD1_k127_1159882_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000007193 83.0
HKD1_k127_1159882_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000727 69.0
HKD1_k127_1188873_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 426.0
HKD1_k127_1188873_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001037 248.0
HKD1_k127_1188873_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000002026 176.0
HKD1_k127_1188873_3 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000003802 181.0
HKD1_k127_1199520_0 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 498.0
HKD1_k127_1199520_1 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000001128 101.0
HKD1_k127_1199520_2 TIGRFAM methyltransferase K08316 - 2.1.1.171 0.00000000000000000004595 97.0
HKD1_k127_1199520_3 Pilus assembly protein, PilP - - - 0.00000000000005549 77.0
HKD1_k127_122018_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 370.0
HKD1_k127_122018_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001098 72.0
HKD1_k127_1238533_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
HKD1_k127_1238533_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000008159 264.0
HKD1_k127_1238533_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000003408 219.0
HKD1_k127_1238533_3 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000003518 207.0
HKD1_k127_1238533_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000002274 81.0
HKD1_k127_1255628_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 323.0
HKD1_k127_1255628_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008284 254.0
HKD1_k127_1255628_2 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000002365 192.0
HKD1_k127_1255628_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000071 129.0
HKD1_k127_1255628_4 - - - - 0.00006409 51.0
HKD1_k127_1295161_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 338.0
HKD1_k127_1295161_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 315.0
HKD1_k127_1295161_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000001061 216.0
HKD1_k127_1295161_3 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000004367 209.0
HKD1_k127_1295161_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000001637 168.0
HKD1_k127_1295161_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000001028 138.0
HKD1_k127_1300408_0 Belongs to the ClpA ClpB family K03696 - - 1.506e-262 835.0
HKD1_k127_1300408_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 466.0
HKD1_k127_1300408_10 MacB-like periplasmic core domain K09808 - - 0.0008042 51.0
HKD1_k127_1300408_2 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 348.0
HKD1_k127_1300408_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000001411 256.0
HKD1_k127_1300408_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005102 246.0
HKD1_k127_1300408_5 serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000004341 194.0
HKD1_k127_1300408_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000788 116.0
HKD1_k127_1300408_7 ribonuclease BN K07058 - - 0.000000000002419 79.0
HKD1_k127_1300408_8 Putative prokaryotic signal transducing protein - - - 0.00004024 51.0
HKD1_k127_1300408_9 Bacterial protein of unknown function (DUF883) - - - 0.00005887 53.0
HKD1_k127_1346970_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 543.0
HKD1_k127_1346970_1 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000009654 209.0
HKD1_k127_1346970_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000001864 164.0
HKD1_k127_1346970_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000004058 108.0
HKD1_k127_1405979_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 355.0
HKD1_k127_1405979_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 312.0
HKD1_k127_1405979_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.0000000000000000000000000000000000000000000000000000000003451 218.0
HKD1_k127_1405979_3 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000006877 100.0
HKD1_k127_1405979_4 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000006515 82.0
HKD1_k127_1405979_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00003666 56.0
HKD1_k127_145035_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 406.0
HKD1_k127_145035_1 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000000000009211 139.0
HKD1_k127_145035_2 Bacterial membrane protein, YfhO - - - 0.000000000000000004863 99.0
HKD1_k127_1480069_0 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000004036 182.0
HKD1_k127_1480069_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000003578 167.0
HKD1_k127_1480069_2 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000008058 117.0
HKD1_k127_1480069_3 Peptidase family M23 K21471 - - 0.000000000000000000003844 108.0
HKD1_k127_1480069_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000004586 84.0
HKD1_k127_1480069_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000001623 53.0
HKD1_k127_1491945_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1305.0
HKD1_k127_1491945_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 234.0
HKD1_k127_1491945_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.0000000000000000000000000000000000000000000002464 173.0
HKD1_k127_1510461_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000505 236.0
HKD1_k127_1510461_1 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.0000000000000000000000000000000000000000000116 170.0
HKD1_k127_1510461_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000001003 149.0
HKD1_k127_1510461_3 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000003369 130.0
HKD1_k127_1510461_4 Winged helix DNA-binding domain - - - 0.00000000000000000000000005263 118.0
HKD1_k127_1510461_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000007265 103.0
HKD1_k127_1510461_6 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.000000000000000000001436 100.0
HKD1_k127_1525389_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 447.0
HKD1_k127_1525389_1 PFAM Sodium sulphate symporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 413.0
HKD1_k127_1533113_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000006542 230.0
HKD1_k127_1533113_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000248 237.0
HKD1_k127_155269_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 613.0
HKD1_k127_155269_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001995 229.0
HKD1_k127_155269_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
HKD1_k127_155269_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000007104 108.0
HKD1_k127_155269_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000001073 68.0
HKD1_k127_1557092_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001715 261.0
HKD1_k127_1587261_0 ligase activity, forming nitrogen-metal bonds K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 472.0
HKD1_k127_1587261_1 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 415.0
HKD1_k127_1587261_2 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000007876 93.0
HKD1_k127_158932_0 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005922 283.0
HKD1_k127_158932_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000001745 170.0
HKD1_k127_158932_2 glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000001706 155.0
HKD1_k127_158932_3 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000002656 92.0
HKD1_k127_158932_4 helix_turn_helix, cAMP Regulatory protein K21562 - - 0.0000001062 55.0
HKD1_k127_159773_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 515.0
HKD1_k127_159773_1 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000006823 239.0
HKD1_k127_159773_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000145 61.0
HKD1_k127_1638319_0 best DB hits BLAST gb AAD45539.1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004848 269.0
HKD1_k127_1638319_1 - - - - 0.0000000004633 66.0
HKD1_k127_1681912_0 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000006424 216.0
HKD1_k127_1681912_1 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000003871 202.0
HKD1_k127_1681912_2 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000000000000007531 150.0
HKD1_k127_1681912_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000002381 141.0
HKD1_k127_1691101_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 353.0
HKD1_k127_1691101_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 326.0
HKD1_k127_1691101_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000001971 108.0
HKD1_k127_1691101_3 Poly A polymerase, head domain K00970 - 2.7.7.19 0.000007465 55.0
HKD1_k127_1701817_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 467.0
HKD1_k127_1701817_1 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 427.0
HKD1_k127_1719489_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000001986 233.0
HKD1_k127_1719489_1 PFAM outer membrane efflux protein - - - 0.0000000000003129 78.0
HKD1_k127_1719489_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000001898 68.0
HKD1_k127_173375_0 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 287.0
HKD1_k127_173375_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000008452 199.0
HKD1_k127_1735656_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000007984 203.0
HKD1_k127_1735656_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000537 134.0
HKD1_k127_17421_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 520.0
HKD1_k127_17421_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
HKD1_k127_1756005_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000004283 220.0
HKD1_k127_1756005_1 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000001211 165.0
HKD1_k127_1756005_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000453 147.0
HKD1_k127_1756005_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000007332 113.0
HKD1_k127_1756005_4 nitrate reductase activity - - - 0.00000000000000000004643 99.0
HKD1_k127_1756305_0 PFAM Transposase DDE domain - - - 0.0000000000000000002762 88.0
HKD1_k127_1774582_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 429.0
HKD1_k127_1774582_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000001545 182.0
HKD1_k127_1774582_2 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000007471 153.0
HKD1_k127_1774582_3 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000003212 100.0
HKD1_k127_1795478_0 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 524.0
HKD1_k127_1795478_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003177 250.0
HKD1_k127_1795478_2 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000004215 87.0
HKD1_k127_1795478_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000001874 69.0
HKD1_k127_183362_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
HKD1_k127_183362_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000002506 145.0
HKD1_k127_1857209_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 454.0
HKD1_k127_1862893_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HKD1_k127_1896395_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000264 194.0
HKD1_k127_1896395_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000002978 136.0
HKD1_k127_1896395_2 Domain of unknown function (DUF4177) - - - 0.000007924 51.0
HKD1_k127_1925288_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 343.0
HKD1_k127_1925288_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000001198 170.0
HKD1_k127_1925288_2 OmpA family K03640 - - 0.0000000000000000000000000000000001682 140.0
HKD1_k127_1925288_3 Outer membrane lipoprotein - - - 0.00000000000000000000000004125 119.0
HKD1_k127_1925288_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000004474 75.0
HKD1_k127_1933712_0 secondary active sulfate transmembrane transporter activity K06901 - - 9.585e-217 687.0
HKD1_k127_1933712_1 B3/4 domain - - - 0.000000000000000000009832 99.0
HKD1_k127_1950236_0 Oligogalacturonate lyase K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 416.0
HKD1_k127_1950236_1 Beta galactosidase small chain K01190 - 3.2.1.23 0.0000000000000000000000000000000000000009283 165.0
HKD1_k127_2012819_0 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000006166 209.0
HKD1_k127_2023256_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 389.0
HKD1_k127_2023256_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
HKD1_k127_2023256_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000008881 200.0
HKD1_k127_2032263_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004534 277.0
HKD1_k127_2032263_1 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000006281 222.0
HKD1_k127_2032263_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000003069 182.0
HKD1_k127_2032263_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000007194 145.0
HKD1_k127_2032263_4 Lipoate-protein ligase - - - 0.000000000000000000000000000000001119 138.0
HKD1_k127_2032263_5 Sporulation and spore germination - - - 0.000000000000008147 82.0
HKD1_k127_2042068_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 338.0
HKD1_k127_2042068_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000002713 144.0
HKD1_k127_20458_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 605.0
HKD1_k127_2075661_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 312.0
HKD1_k127_2075661_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000013 218.0
HKD1_k127_2075661_2 NMT1-like family K02051 - - 0.00000000000000000000000000000007091 134.0
HKD1_k127_2075661_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000004419 91.0
HKD1_k127_2077316_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000002394 230.0
HKD1_k127_2077316_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000001116 140.0
HKD1_k127_2077316_2 Contains selenocysteine K07401 - - 0.00000000000001531 74.0
HKD1_k127_2077902_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1412.0
HKD1_k127_2077902_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
HKD1_k127_2077902_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
HKD1_k127_2077902_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD1_k127_2077902_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000001513 153.0
HKD1_k127_2077902_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000266 127.0
HKD1_k127_2077902_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005742 80.0
HKD1_k127_2077902_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000017 76.0
HKD1_k127_2077902_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000004761 55.0
HKD1_k127_2079231_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 396.0
HKD1_k127_2079231_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000003336 175.0
HKD1_k127_2079231_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000006327 129.0
HKD1_k127_2079231_3 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000009672 70.0
HKD1_k127_2079231_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000003735 64.0
HKD1_k127_210620_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.975e-240 765.0
HKD1_k127_210620_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004629 279.0
HKD1_k127_210620_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000006733 164.0
HKD1_k127_210620_3 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000007456 121.0
HKD1_k127_210620_4 outer membrane autotransporter barrel domain protein - - - 0.000000000009323 74.0
HKD1_k127_2108742_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 315.0
HKD1_k127_2108742_1 Histidine kinase - - - 0.0001992 50.0
HKD1_k127_2117051_0 Protein of unknown function (DUF2723) - - - 0.0000000265 67.0
HKD1_k127_2119306_0 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 368.0
HKD1_k127_2119306_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000006229 194.0
HKD1_k127_2119306_2 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000001814 85.0
HKD1_k127_2146643_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000001033 221.0
HKD1_k127_2146643_1 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000000001638 201.0
HKD1_k127_2146643_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000003209 149.0
HKD1_k127_2146643_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000001736 113.0
HKD1_k127_2146643_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001799 108.0
HKD1_k127_2146643_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000006022 93.0
HKD1_k127_215723_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 366.0
HKD1_k127_215723_1 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000306 104.0
HKD1_k127_2166177_0 PFAM Type II secretion system protein E K02652 - - 1.472e-213 685.0
HKD1_k127_2166177_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 298.0
HKD1_k127_2166177_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000002463 115.0
HKD1_k127_2166177_3 Pilus assembly protein K02662 - - 0.000002129 60.0
HKD1_k127_2172884_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HKD1_k127_2176337_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000001534 196.0
HKD1_k127_2176337_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000007439 185.0
HKD1_k127_2176337_2 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000008664 162.0
HKD1_k127_2177388_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000001238 229.0
HKD1_k127_2177388_1 membrane - - - 0.00008408 53.0
HKD1_k127_2180070_0 Adenylate and Guanylate cyclase catalytic domain - - - 4.285e-212 670.0
HKD1_k127_218434_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 315.0
HKD1_k127_218434_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 319.0
HKD1_k127_2202647_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 559.0
HKD1_k127_2202647_1 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 498.0
HKD1_k127_2202647_2 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 360.0
HKD1_k127_2202647_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000003029 211.0
HKD1_k127_2202647_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000001892 149.0
HKD1_k127_2202647_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000001027 87.0
HKD1_k127_2202647_6 energy transducer activity - - - 0.000000000003624 77.0
HKD1_k127_2202647_7 Fibronectin type 3 domain - - - 0.00000004451 64.0
HKD1_k127_2214596_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.277e-249 784.0
HKD1_k127_2214596_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000032 209.0
HKD1_k127_2214596_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000006937 140.0
HKD1_k127_2214596_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002523 127.0
HKD1_k127_2233991_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000001552 114.0
HKD1_k127_2233991_1 Roadblock/LC7 domain - - - 0.00000008622 60.0
HKD1_k127_2233991_2 peptidyl-tyrosine sulfation - - - 0.00002215 55.0
HKD1_k127_2233991_3 HD domain - - - 0.0003328 44.0
HKD1_k127_2265249_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 385.0
HKD1_k127_2265249_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000114 108.0
HKD1_k127_2265249_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001203 76.0
HKD1_k127_2265249_3 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001429 68.0
HKD1_k127_2265249_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000006712 57.0
HKD1_k127_2280082_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 394.0
HKD1_k127_2280082_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 333.0
HKD1_k127_2280082_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000001205 219.0
HKD1_k127_2280082_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000006842 175.0
HKD1_k127_2280082_4 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000002506 142.0
HKD1_k127_2280082_5 oligopeptide transport K03305 - - 0.000000000000000000000000000000001874 136.0
HKD1_k127_2298859_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 427.0
HKD1_k127_2298859_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 410.0
HKD1_k127_2298859_2 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000001486 222.0
HKD1_k127_2298859_4 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.00007814 47.0
HKD1_k127_230417_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 616.0
HKD1_k127_230417_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 490.0
HKD1_k127_230417_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
HKD1_k127_230417_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K15876 - - 0.0000000000000000000000000000000000000000000004038 171.0
HKD1_k127_230417_4 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000004552 147.0
HKD1_k127_230417_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000002609 150.0
HKD1_k127_230417_6 cytochrome c - - - 0.00000000000000000000000008614 115.0
HKD1_k127_230417_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000001652 117.0
HKD1_k127_230417_8 Protein of unknown function (DUF3341) - - - 0.000000000000000002705 91.0
HKD1_k127_230417_9 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000006204 93.0
HKD1_k127_2320106_0 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 346.0
HKD1_k127_2355774_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 500.0
HKD1_k127_2355774_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000001078 63.0
HKD1_k127_2379704_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 310.0
HKD1_k127_2379704_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 301.0
HKD1_k127_2379704_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000187 150.0
HKD1_k127_2379704_3 - - - - 0.0004087 50.0
HKD1_k127_2398458_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 435.0
HKD1_k127_2398458_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000819 213.0
HKD1_k127_2398458_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000009119 204.0
HKD1_k127_2398458_3 - - - - 0.000000000000000000000000000947 126.0
HKD1_k127_2398458_4 heat shock protein binding K03686 - - 0.00000000000000002545 90.0
HKD1_k127_2398458_5 - - - - 0.00000000000000005763 90.0
HKD1_k127_2398458_6 PEGA domain K15539 - - 0.00000000002022 74.0
HKD1_k127_2398458_7 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000002491 71.0
HKD1_k127_2401175_0 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000005198 151.0
HKD1_k127_2401175_1 Belongs to the universal stress protein A family - - - 0.00000000000000000005459 95.0
HKD1_k127_2401175_2 Glycosyl transferases group 1 - - - 0.00000000000002581 82.0
HKD1_k127_2401175_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000001733 59.0
HKD1_k127_2402729_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001427 274.0
HKD1_k127_2402729_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001969 270.0
HKD1_k127_2402729_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000006045 168.0
HKD1_k127_2413714_0 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000002229 229.0
HKD1_k127_2413714_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
HKD1_k127_2413714_2 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000001429 154.0
HKD1_k127_2413714_3 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000002362 152.0
HKD1_k127_2413714_4 Polymer-forming cytoskeletal - - - 0.000001505 60.0
HKD1_k127_2442964_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 394.0
HKD1_k127_2442964_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 323.0
HKD1_k127_2442964_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
HKD1_k127_2442964_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000002099 264.0
HKD1_k127_2442964_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000006087 192.0
HKD1_k127_2442964_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000001498 74.0
HKD1_k127_2496502_0 elongation factor G K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 426.0
HKD1_k127_2496502_1 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000005894 54.0
HKD1_k127_2526789_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.926e-253 799.0
HKD1_k127_2526789_1 PFAM glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 350.0
HKD1_k127_2526789_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 304.0
HKD1_k127_2526789_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000008355 251.0
HKD1_k127_2526789_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000003001 214.0
HKD1_k127_2526789_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000005847 186.0
HKD1_k127_2526789_6 Glycosyl transferases group 1 - - - 0.00000000000000127 89.0
HKD1_k127_2526789_7 PFAM Outer membrane K06142 - - 0.0000000001975 68.0
HKD1_k127_2539330_0 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 445.0
HKD1_k127_2562796_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000008944 234.0
HKD1_k127_2562796_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000005375 188.0
HKD1_k127_2562796_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000004965 168.0
HKD1_k127_2562796_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000007476 159.0
HKD1_k127_2562796_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000003295 63.0
HKD1_k127_2578305_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 325.0
HKD1_k127_2578305_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005869 279.0
HKD1_k127_2578305_2 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000000000000000000000007375 193.0
HKD1_k127_2578305_3 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.00000000000001168 78.0
HKD1_k127_2578305_4 DUF218 domain - - - 0.000000008824 66.0
HKD1_k127_2612511_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 585.0
HKD1_k127_2612511_1 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 460.0
HKD1_k127_2612511_2 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000003138 213.0
HKD1_k127_2612511_3 Carboxypeptidase regulatory-like domain - - - 0.0000006716 54.0
HKD1_k127_2626607_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 566.0
HKD1_k127_2631808_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 588.0
HKD1_k127_2631808_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000143 209.0
HKD1_k127_2631808_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000007297 195.0
HKD1_k127_2783668_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 623.0
HKD1_k127_2783668_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 360.0
HKD1_k127_2783668_2 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004484 263.0
HKD1_k127_2861471_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
HKD1_k127_2861471_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000165 183.0
HKD1_k127_2861471_2 protein-disulfide reductase activity - - - 0.00000000000000000000001344 113.0
HKD1_k127_294388_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1033.0
HKD1_k127_294388_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000005202 90.0
HKD1_k127_294388_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000002986 85.0
HKD1_k127_30014_0 Von Willebrand factor type A domain K07114 - - 0.000000001433 71.0
HKD1_k127_30014_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0008138 45.0
HKD1_k127_3011949_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000008645 249.0
HKD1_k127_3011949_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000001443 179.0
HKD1_k127_3011949_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000006612 153.0
HKD1_k127_3021238_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 363.0
HKD1_k127_3021238_1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000008457 233.0
HKD1_k127_302860_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006114 284.0
HKD1_k127_302860_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001036 228.0
HKD1_k127_302860_2 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000000000000000008972 118.0
HKD1_k127_302860_3 Helix-hairpin-helix motif K02237 - - 0.0000000000000001183 87.0
HKD1_k127_302860_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000004438 62.0
HKD1_k127_302860_5 CYTH K05873 - 4.6.1.1 0.000003652 51.0
HKD1_k127_3059444_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 345.0
HKD1_k127_3059444_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 308.0
HKD1_k127_3059444_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000002508 238.0
HKD1_k127_3059444_3 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000001525 184.0
HKD1_k127_3059444_4 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000002294 125.0
HKD1_k127_3059444_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000002962 91.0
HKD1_k127_3059444_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000474 62.0
HKD1_k127_3061290_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 431.0
HKD1_k127_3183804_0 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000195 131.0
HKD1_k127_3183804_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000406 99.0
HKD1_k127_3183804_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000002778 88.0
HKD1_k127_3184944_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 527.0
HKD1_k127_3184944_1 - - - - 0.0000000006944 61.0
HKD1_k127_3208058_0 PFAM HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 368.0
HKD1_k127_3208058_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 364.0
HKD1_k127_3208058_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000003456 204.0
HKD1_k127_3208058_3 protein kinase activity - - - 0.000000000000000000000000000000000003698 157.0
HKD1_k127_3208058_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000006936 123.0
HKD1_k127_3208058_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000001322 82.0
HKD1_k127_3224328_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 469.0
HKD1_k127_3224328_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000003894 111.0
HKD1_k127_322950_0 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000009227 188.0
HKD1_k127_322950_1 - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000007198 61.0
HKD1_k127_3232897_0 protein kinase activity - - - 0.000000000167 74.0
HKD1_k127_3238857_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 416.0
HKD1_k127_3238857_1 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000000000000000001287 103.0
HKD1_k127_3238857_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000211 77.0
HKD1_k127_3258647_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 393.0
HKD1_k127_3258647_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
HKD1_k127_3258647_2 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003346 255.0
HKD1_k127_3258647_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000006931 192.0
HKD1_k127_3258647_4 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000005687 174.0
HKD1_k127_3258647_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000008207 126.0
HKD1_k127_3258647_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.00000000000000000000000000005702 117.0
HKD1_k127_326102_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 302.0
HKD1_k127_326102_1 response to pH - - - 0.000000000000000000255 90.0
HKD1_k127_3273566_0 methionine adenosyltransferase activity K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000005541 198.0
HKD1_k127_3273566_1 Archease protein family (MTH1598/TM1083) - - - 0.0001298 49.0
HKD1_k127_3287033_0 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000002196 134.0
HKD1_k127_3287033_1 Domain of unknown function (DUF374) - - - 0.000000000000000000000000001501 120.0
HKD1_k127_3287033_2 lysyltransferase activity K07027 - - 0.000000006921 67.0
HKD1_k127_3318885_0 B12 binding domain - - - 8.078e-200 633.0
HKD1_k127_3318885_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000001607 223.0
HKD1_k127_3318885_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000561 130.0
HKD1_k127_3318885_3 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000001922 119.0
HKD1_k127_3318885_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000002594 81.0
HKD1_k127_3320543_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.578e-306 952.0
HKD1_k127_3320543_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006657 230.0
HKD1_k127_3320543_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
HKD1_k127_3320543_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000002071 108.0
HKD1_k127_3320543_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000004047 73.0
HKD1_k127_3349957_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 371.0
HKD1_k127_3349957_1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16784,K16786 - - 0.0000000000001566 77.0
HKD1_k127_3349957_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.000008414 57.0
HKD1_k127_3349957_3 ABC transporter K02013 - 3.6.3.34 0.0001283 55.0
HKD1_k127_3394298_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 9.275e-202 632.0
HKD1_k127_3394298_1 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 552.0
HKD1_k127_3394298_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 418.0
HKD1_k127_3394298_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 360.0
HKD1_k127_3394298_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000002129 139.0
HKD1_k127_3394298_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000003603 70.0
HKD1_k127_3423087_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002416 290.0
HKD1_k127_3423087_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000005655 254.0
HKD1_k127_3423087_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HKD1_k127_3423087_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000006192 176.0
HKD1_k127_3423087_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000001368 131.0
HKD1_k127_3423087_5 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000008728 117.0
HKD1_k127_3423087_6 Protein of unknown function (DUF2721) - - - 0.0000000000000001708 91.0
HKD1_k127_3453334_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000002939 239.0
HKD1_k127_3453334_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000001076 209.0
HKD1_k127_3453334_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000002568 124.0
HKD1_k127_3467687_0 Stress-induced protein - - - 0.000000000000000000000000000000000003906 152.0
HKD1_k127_3467687_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000007429 124.0
HKD1_k127_3467687_2 Protein of unknown function (DUF2723) - - - 0.00000000000000008248 94.0
HKD1_k127_3541361_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000048 219.0
HKD1_k127_3541361_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000002934 172.0
HKD1_k127_3541361_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000007722 113.0
HKD1_k127_3541361_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00002335 56.0
HKD1_k127_3588182_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 427.0
HKD1_k127_3588182_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 332.0
HKD1_k127_3588182_2 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000002138 168.0
HKD1_k127_3588182_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000002026 143.0
HKD1_k127_3609063_0 hydrolase - - - 0.00000000000000000000000000000000001421 144.0
HKD1_k127_3609063_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000001563 110.0
HKD1_k127_3754828_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000586 229.0
HKD1_k127_3754828_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.00004038 53.0
HKD1_k127_3754828_2 PFAM cytochrome c assembly protein K02198 - - 0.0001866 53.0
HKD1_k127_380321_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.024e-219 703.0
HKD1_k127_380321_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005491 262.0
HKD1_k127_380321_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000005881 148.0
HKD1_k127_380321_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000001689 93.0
HKD1_k127_382453_0 Oligopeptide transporter OPT - - - 1.708e-250 792.0
HKD1_k127_382453_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000005775 149.0
HKD1_k127_382453_2 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.000000001806 60.0
HKD1_k127_3849946_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 374.0
HKD1_k127_3849946_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 309.0
HKD1_k127_3849946_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000002361 135.0
HKD1_k127_38560_0 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000004047 181.0
HKD1_k127_38560_1 TonB-dependent Receptor Plug K02014,K16089 - - 0.000007889 54.0
HKD1_k127_3912834_0 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 413.0
HKD1_k127_3920551_0 - - - - 0.000000003618 65.0
HKD1_k127_393468_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 318.0
HKD1_k127_393468_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000203 250.0
HKD1_k127_393468_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
HKD1_k127_393468_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000001281 181.0
HKD1_k127_393468_4 - - - - 0.0000003104 63.0
HKD1_k127_40215_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 352.0
HKD1_k127_40215_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 306.0
HKD1_k127_40215_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
HKD1_k127_40215_3 alpha beta - - - 0.00001397 57.0
HKD1_k127_40215_4 Intraflagellar transport protein 88 K16474 GO:0000003,GO:0000226,GO:0000902,GO:0000904,GO:0001578,GO:0001654,GO:0001655,GO:0001669,GO:0001822,GO:0001885,GO:0001886,GO:0001889,GO:0001944,GO:0002064,GO:0002080,GO:0002081,GO:0002119,GO:0002164,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003158,GO:0003205,GO:0003206,GO:0003279,GO:0003382,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005813,GO:0005814,GO:0005815,GO:0005856,GO:0005929,GO:0005930,GO:0006810,GO:0006928,GO:0006950,GO:0006970,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007018,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007224,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007288,GO:0007289,GO:0007290,GO:0007368,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007507,GO:0007600,GO:0007605,GO:0007610,GO:0007626,GO:0008092,GO:0008104,GO:0008150,GO:0008283,GO:0008285,GO:0008544,GO:0008589,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009894,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010506,GO:0010646,GO:0010647,GO:0010970,GO:0012505,GO:0012506,GO:0014706,GO:0015630,GO:0016020,GO:0016043,GO:0016241,GO:0019222,GO:0019894,GO:0019953,GO:0021510,GO:0021511,GO:0021513,GO:0021537,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022611,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030031,GO:0030141,GO:0030154,GO:0030162,GO:0030182,GO:0030317,GO:0030323,GO:0030324,GO:0030326,GO:0030659,GO:0030667,GO:0030705,GO:0030855,GO:0030900,GO:0030990,GO:0030992,GO:0031016,GO:0031090,GO:0031122,GO:0031175,GO:0031323,GO:0031329,GO:0031344,GO:0031410,GO:0031503,GO:0031514,GO:0031982,GO:0031984,GO:0032101,GO:0032103,GO:0032391,GO:0032421,GO:0032501,GO:0032502,GO:0032504,GO:0032838,GO:0032989,GO:0032991,GO:0033036,GO:0033043,GO:0034405,GO:0035051,GO:0035082,GO:0035107,GO:0035108,GO:0035113,GO:0035295,GO:0035640,GO:0035641,GO:0035735,GO:0035869,GO:0036064,GO:0036334,GO:0040011,GO:0040012,GO:0040017,GO:0040024,GO:0042073,GO:0042127,GO:0042481,GO:0042487,GO:0042490,GO:0042592,GO:0042692,GO:0042733,GO:0042995,GO:0043005,GO:0043053,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043567,GO:0043568,GO:0043583,GO:0044085,GO:0044087,GO:0044088,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044431,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044447,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045446,GO:0045595,GO:0045598,GO:0046907,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048645,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048732,GO:0048736,GO:0048738,GO:0048839,GO:0048853,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048872,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050877,GO:0050896,GO:0050920,GO:0050921,GO:0050954,GO:0051128,GO:0051146,GO:0051171,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0055007,GO:0055115,GO:0060021,GO:0060091,GO:0060113,GO:0060119,GO:0060122,GO:0060173,GO:0060255,GO:0060259,GO:0060271,GO:0060322,GO:0060411,GO:0060426,GO:0060429,GO:0060491,GO:0060537,GO:0060541,GO:0060914,GO:0061008,GO:0061061,GO:0061351,GO:0065007,GO:0065008,GO:0070613,GO:0070925,GO:0071840,GO:0072001,GO:0072358,GO:0072359,GO:0080090,GO:0090102,GO:0097014,GO:0097223,GO:0097435,GO:0097458,GO:0097541,GO:0097542,GO:0097546,GO:0097708,GO:0097722,GO:0097730,GO:0097731,GO:0097732,GO:0097733,GO:0098588,GO:0098589,GO:0098791,GO:0098805,GO:0098862,GO:0099111,GO:0099503,GO:0099568,GO:0120025,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0120038,GO:1902017,GO:1902115,GO:1903317,GO:1903929,GO:1905515,GO:2000026,GO:2000027,GO:2000785 - 0.0000258 55.0
HKD1_k127_40215_5 domain, Protein - - - 0.0001645 51.0
HKD1_k127_4037237_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 392.0
HKD1_k127_4037237_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
HKD1_k127_4037237_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000275 210.0
HKD1_k127_4037237_3 PFAM YbbR family protein - - - 0.0000000000000000000002547 106.0
HKD1_k127_4037237_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000002538 75.0
HKD1_k127_4049655_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003763 271.0
HKD1_k127_4049655_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000003871 261.0
HKD1_k127_4049655_2 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000001794 181.0
HKD1_k127_4049655_3 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000192 100.0
HKD1_k127_4065556_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 374.0
HKD1_k127_4065556_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 296.0
HKD1_k127_4086441_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 382.0
HKD1_k127_4086441_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000001163 77.0
HKD1_k127_4105808_0 N-acetylglucosaminylinositol deacetylase activity K22136 - - 5.259e-238 762.0
HKD1_k127_4105808_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000001619 133.0
HKD1_k127_4105808_2 Amidase - - - 0.000000006498 63.0
HKD1_k127_4146120_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000009109 129.0
HKD1_k127_4146120_1 PAS domain K07652 - 2.7.13.3 0.0000000000000000000022 99.0
HKD1_k127_4146120_2 cheY-homologous receiver domain - - - 0.0000000000006306 71.0
HKD1_k127_4158112_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 2.058e-216 695.0
HKD1_k127_4158112_1 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 618.0
HKD1_k127_4158112_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001543 288.0
HKD1_k127_4158112_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 261.0
HKD1_k127_4158112_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001585 253.0
HKD1_k127_4158112_5 Elongation factor P, C-terminal K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000006966 189.0
HKD1_k127_4158112_6 SNARE associated Golgi protein K03975 - - 0.00000002786 55.0
HKD1_k127_4169950_0 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000395 233.0
HKD1_k127_4169950_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000008338 83.0
HKD1_k127_4177055_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 7.614e-199 630.0
HKD1_k127_4177055_1 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000002579 191.0
HKD1_k127_4177055_2 - - - - 0.0000000000000000000007944 104.0
HKD1_k127_4177055_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000001274 60.0
HKD1_k127_4187555_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.769e-258 807.0
HKD1_k127_4187555_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000006546 174.0
HKD1_k127_4187555_2 histidine kinase HAMP region domain protein K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000001266 106.0
HKD1_k127_4211229_0 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000291 129.0
HKD1_k127_4211229_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000007443 57.0
HKD1_k127_4211229_3 TIGRFAM TonB family C-terminal domain K03832 - - 0.000003715 59.0
HKD1_k127_4230249_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000001025 190.0
HKD1_k127_4230249_1 Peptidase, M28 - - - 0.0006342 53.0
HKD1_k127_4241274_0 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HKD1_k127_4241274_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004297 269.0
HKD1_k127_4241274_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000002116 164.0
HKD1_k127_4241274_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000001988 93.0
HKD1_k127_4241274_4 DinB superfamily - - - 0.000000000009117 74.0
HKD1_k127_4260655_0 PFAM PHP domain protein K01104 - 3.1.3.48 0.000000000000000002221 88.0
HKD1_k127_4262110_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000006198 165.0
HKD1_k127_4285815_0 Ras family - - - 0.000000000000000000000000000000000000000000000000000000001392 223.0
HKD1_k127_4285815_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000001588 186.0
HKD1_k127_4285815_2 histidine kinase HAMP region domain protein - - - 0.0000215 57.0
HKD1_k127_429049_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 428.0
HKD1_k127_429049_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 337.0
HKD1_k127_429049_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HKD1_k127_429049_3 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000002194 214.0
HKD1_k127_429049_4 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000009032 153.0
HKD1_k127_429049_5 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000001154 136.0
HKD1_k127_429049_6 - - - - 0.000000000000000000000005489 111.0
HKD1_k127_4324071_0 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000003334 243.0
HKD1_k127_4324071_1 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000001104 213.0
HKD1_k127_4329236_0 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 355.0
HKD1_k127_4329236_1 mitochondrial electron transport, ubiquinol to cytochrome c K01412,K07263,K17732 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005759,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016787,GO:0017087,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0023052,GO:0031090,GO:0031930,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045275,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0065007,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 3.4.24.64 0.000000000000000000000000000000000000000000000000000006192 196.0
HKD1_k127_4357482_0 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
HKD1_k127_4357482_1 B12 binding domain - - - 0.0000000002079 64.0
HKD1_k127_4363609_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 508.0
HKD1_k127_4363609_1 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 439.0
HKD1_k127_4363609_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 388.0
HKD1_k127_4363609_3 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 343.0
HKD1_k127_4363609_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
HKD1_k127_4363609_5 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
HKD1_k127_4363609_6 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000003646 204.0
HKD1_k127_4363609_7 Transcription factor zinc-finger K09981 - - 0.000000000000000000001255 101.0
HKD1_k127_4363609_8 Tetratricopeptide repeat - - - 0.0000004637 63.0
HKD1_k127_4380158_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000001659 201.0
HKD1_k127_4380158_1 arylsulfatase A - - - 0.00000000002928 68.0
HKD1_k127_4398912_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 286.0
HKD1_k127_4398912_1 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
HKD1_k127_4398912_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000005458 216.0
HKD1_k127_4399207_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 539.0
HKD1_k127_4399207_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 313.0
HKD1_k127_4399207_2 Rubrerythrin - - - 0.00005135 49.0
HKD1_k127_4399861_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 371.0
HKD1_k127_4399861_1 ApaG domain K06195 - - 0.0000000000000000000000006699 106.0
HKD1_k127_44007_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000001374 225.0
HKD1_k127_44007_1 Glycosyl transferases group 1 - - - 0.0000000000000005916 83.0
HKD1_k127_4435209_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 450.0
HKD1_k127_4461058_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.882e-289 908.0
HKD1_k127_4461058_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 550.0
HKD1_k127_4461058_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 286.0
HKD1_k127_4461058_3 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000003467 157.0
HKD1_k127_448153_0 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000000000000000000008211 192.0
HKD1_k127_4507148_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 428.0
HKD1_k127_4507148_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000003534 88.0
HKD1_k127_4616093_0 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 383.0
HKD1_k127_4616093_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 368.0
HKD1_k127_4616093_2 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
HKD1_k127_4616093_3 - - - - 0.0000000000000000000000000003396 117.0
HKD1_k127_4616093_4 Transcriptional regulator - - - 0.000000000000000000000005411 110.0
HKD1_k127_4621166_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
HKD1_k127_4621166_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000001563 198.0
HKD1_k127_4621166_2 Tetratricopeptide repeat - - - 0.0000000000001286 84.0
HKD1_k127_4621166_3 Domain of unknown function (DUF1844) - - - 0.000007344 53.0
HKD1_k127_4638552_0 PhoQ Sensor K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001502 216.0
HKD1_k127_4638552_1 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000004353 114.0
HKD1_k127_4667961_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009185 283.0
HKD1_k127_4667961_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000277 224.0
HKD1_k127_4667961_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000002458 183.0
HKD1_k127_4667961_3 Cytidylyltransferase family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000001278 59.0
HKD1_k127_4733060_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000008525 252.0
HKD1_k127_4733060_1 Belongs to the RimK family K05844 - - 0.00000000000000006696 85.0
HKD1_k127_4812189_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 432.0
HKD1_k127_4812189_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 341.0
HKD1_k127_4845628_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 446.0
HKD1_k127_4845628_1 HIT domain K02503 - - 0.000000000000000000000000000000000000005275 157.0
HKD1_k127_4845628_2 2'-5' RNA ligase superfamily - - - 0.000255 47.0
HKD1_k127_48702_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.336e-200 635.0
HKD1_k127_48702_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000642 237.0
HKD1_k127_48702_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000006195 97.0
HKD1_k127_4883861_0 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 330.0
HKD1_k127_4883861_1 Transcriptional regulator K07979 - - 0.0000000000000000000000000000000000000000004886 161.0
HKD1_k127_4883861_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000004135 117.0
HKD1_k127_488939_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000005737 190.0
HKD1_k127_488939_1 Diguanylate cyclase - - - 0.0000000000000000000000245 107.0
HKD1_k127_488939_2 - - - - 0.00000000000009115 76.0
HKD1_k127_488939_3 Putative regulatory protein - - - 0.000000005254 61.0
HKD1_k127_4921524_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000003839 200.0
HKD1_k127_4921524_1 TIGRFAM TonB K03832 - - 0.00001235 57.0
HKD1_k127_4921569_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 398.0
HKD1_k127_4921569_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000001069 67.0
HKD1_k127_4921569_2 Bacterial regulatory proteins, tetR family - - - 0.0000001203 61.0
HKD1_k127_4933305_0 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
HKD1_k127_4933305_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HKD1_k127_4933305_2 Lrp/AsnC ligand binding domain - - - 0.00000000000000001128 86.0
HKD1_k127_4986558_0 Enolase, C-terminal TIM barrel domain K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 518.0
HKD1_k127_4986558_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 441.0
HKD1_k127_4986558_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 354.0
HKD1_k127_4986558_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 272.0
HKD1_k127_4986558_4 peptidase inhibitor activity - - - 0.000000000000000009566 98.0
HKD1_k127_4986558_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000145 89.0
HKD1_k127_5032145_0 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 297.0
HKD1_k127_5032145_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000004218 213.0
HKD1_k127_5035383_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 534.0
HKD1_k127_5038208_0 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 417.0
HKD1_k127_5038208_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 325.0
HKD1_k127_5038208_2 Uracil DNA glycosylase superfamily - - - 0.0000000011 59.0
HKD1_k127_5040322_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 3.689e-249 812.0
HKD1_k127_5040322_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000873 187.0
HKD1_k127_5040322_2 - - - - 0.0000000000000000000000000000009245 130.0
HKD1_k127_5040322_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000009587 116.0
HKD1_k127_5040322_4 recA bacterial DNA recombination protein - - - 0.00000000000000000000002264 115.0
HKD1_k127_5040322_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000001521 102.0
HKD1_k127_5040322_6 - - - - 0.00000000002167 68.0
HKD1_k127_5040322_7 Helix-turn-helix XRE-family like proteins - - - 0.000001669 58.0
HKD1_k127_5041238_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 421.0
HKD1_k127_5041238_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 319.0
HKD1_k127_5041238_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002089 242.0
HKD1_k127_5041238_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000001415 119.0
HKD1_k127_5041238_4 Regulatory protein, FmdB family - - - 0.00000000000000000003104 95.0
HKD1_k127_5041238_5 Domain of unknown function (DUF4388) - - - 0.00000005599 63.0
HKD1_k127_5041238_6 Type II secretion system (T2SS), protein F K02653 - - 0.0000003388 51.0
HKD1_k127_5043616_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 8.019e-220 702.0
HKD1_k127_5043616_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000007823 234.0
HKD1_k127_5043616_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000005142 224.0
HKD1_k127_5043616_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000008088 127.0
HKD1_k127_5043616_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000008485 97.0
HKD1_k127_5062090_0 -O-antigen K02847,K13009 - - 0.00000000989 68.0
HKD1_k127_5062090_1 Bacterial membrane protein YfhO - - - 0.0000007958 57.0
HKD1_k127_5063181_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 620.0
HKD1_k127_5063181_1 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 467.0
HKD1_k127_5063181_11 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000005515 81.0
HKD1_k127_5063181_12 Glycine N-methyltransferase-like K00552 GO:0000096,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0006073,GO:0006082,GO:0006091,GO:0006109,GO:0006111,GO:0006112,GO:0006139,GO:0006464,GO:0006520,GO:0006534,GO:0006544,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0006950,GO:0007154,GO:0007275,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008340,GO:0008652,GO:0008757,GO:0009056,GO:0009058,GO:0009066,GO:0009069,GO:0009109,GO:0009116,GO:0009119,GO:0009267,GO:0009605,GO:0009889,GO:0009987,GO:0009991,GO:0010259,GO:0010675,GO:0010906,GO:0015980,GO:0016043,GO:0016053,GO:0016594,GO:0016597,GO:0016740,GO:0016741,GO:0017144,GO:0017174,GO:0019222,GO:0019538,GO:0019752,GO:0019842,GO:0022607,GO:0031323,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0032259,GO:0032501,GO:0032502,GO:0032991,GO:0033218,GO:0033353,GO:0033554,GO:0034641,GO:0034708,GO:0036094,GO:0036211,GO:0042133,GO:0042165,GO:0042278,GO:0042398,GO:0042558,GO:0042592,GO:0042594,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043255,GO:0043412,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044273,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046655,GO:0048037,GO:0048856,GO:0048878,GO:0050662,GO:0050789,GO:0050794,GO:0050843,GO:0050896,GO:0051186,GO:0051187,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055086,GO:0055088,GO:0055090,GO:0055114,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070328,GO:0071496,GO:0071704,GO:0071840,GO:0072341,GO:0072521,GO:0080090,GO:0097159,GO:0098603,GO:1901052,GO:1901054,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901681,GO:1902494,GO:1904047,GO:1990234 2.1.1.20 0.0000305 55.0
HKD1_k127_5063181_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 418.0
HKD1_k127_5063181_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 365.0
HKD1_k127_5063181_4 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 336.0
HKD1_k127_5063181_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 318.0
HKD1_k127_5063181_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000006254 242.0
HKD1_k127_5063181_7 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000000001917 188.0
HKD1_k127_5063181_8 amidohydrolase - - - 0.00000000000000000000000000000000002514 153.0
HKD1_k127_5063181_9 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.000000000000000000000000000003995 128.0
HKD1_k127_5081033_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
HKD1_k127_5081033_1 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.00000000000000000000000000000000000000005195 165.0
HKD1_k127_5081033_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000002936 106.0
HKD1_k127_5082541_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 307.0
HKD1_k127_5082541_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000002005 219.0
HKD1_k127_5082541_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000002934 216.0
HKD1_k127_5082541_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000004204 185.0
HKD1_k127_5082541_4 lipase activity K15349 - - 0.00000000000000000000000000000000000000000004794 177.0
HKD1_k127_5082541_5 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000001741 167.0
HKD1_k127_5082541_6 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000002628 90.0
HKD1_k127_5082541_7 antisigma factor binding - - - 0.0000000000000000287 89.0
HKD1_k127_5082541_8 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0007529 46.0
HKD1_k127_5093225_0 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000117 153.0
HKD1_k127_5098855_0 Acetyltransferase (GNAT) domain - - - 0.00000109 58.0
HKD1_k127_5098855_1 Bacterial membrane protein, YfhO - - - 0.000008146 58.0
HKD1_k127_5106075_0 carbohydrate binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 555.0
HKD1_k127_5122778_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 368.0
HKD1_k127_5122778_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 321.0
HKD1_k127_5122778_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 297.0
HKD1_k127_5122778_3 Deoxynucleoside kinase K10353 - 2.7.1.76 0.0000000000000000000000000000000000000000000000000004562 190.0
HKD1_k127_5122778_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000002176 154.0
HKD1_k127_5122778_5 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000006378 141.0
HKD1_k127_5122778_6 PAP2 superfamily - - - 0.00000000000000000000000002608 122.0
HKD1_k127_5122778_7 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000003817 79.0
HKD1_k127_5122778_8 PFAM Sporulation domain protein K03749 - - 0.00001221 55.0
HKD1_k127_5127496_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.505e-267 838.0
HKD1_k127_5127496_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 556.0
HKD1_k127_5127496_2 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000001726 226.0
HKD1_k127_5127496_3 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000003612 131.0
HKD1_k127_5127496_4 PFAM Thiamin pyrophosphokinase catalytic K00949 - 2.7.6.2 0.000000000000000000002857 101.0
HKD1_k127_5127496_5 Protein of unknown function (DUF971) K03593 - - 0.00000000000000009476 84.0
HKD1_k127_5134744_0 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000006061 142.0
HKD1_k127_5134744_1 - - - - 0.0000000000001035 81.0
HKD1_k127_5134744_2 - - - - 0.000000006555 66.0
HKD1_k127_5142244_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003097 282.0
HKD1_k127_5142244_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001201 252.0
HKD1_k127_5172993_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 535.0
HKD1_k127_5172993_1 PFAM response regulator receiver K07657 - - 0.00000000000000000000000003347 112.0
HKD1_k127_5184255_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.158e-231 743.0
HKD1_k127_5184255_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 469.0
HKD1_k127_5184255_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0009163 43.0
HKD1_k127_5184255_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 448.0
HKD1_k127_5184255_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 407.0
HKD1_k127_5184255_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 290.0
HKD1_k127_5184255_5 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 282.0
HKD1_k127_5184255_6 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001314 301.0
HKD1_k127_5184255_7 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000001777 239.0
HKD1_k127_5184255_8 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000001395 124.0
HKD1_k127_5184255_9 COG0457 FOG TPR repeat - - - 0.0002768 48.0
HKD1_k127_5185607_0 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 451.0
HKD1_k127_5185607_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 436.0
HKD1_k127_5185607_2 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000002443 230.0
HKD1_k127_5185607_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000003425 185.0
HKD1_k127_5185607_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000006245 175.0
HKD1_k127_5185607_5 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000005006 153.0
HKD1_k127_5185607_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000002226 120.0
HKD1_k127_5185607_7 protein-disulfide reductase activity - - - 0.000000000000000000000001568 109.0
HKD1_k127_5185607_8 Protein of unknown function (DUF2723) - - - 0.0000000000001752 84.0
HKD1_k127_5189554_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000007277 180.0
HKD1_k127_5189554_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000001204 147.0
HKD1_k127_5189554_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000003943 90.0
HKD1_k127_5191590_0 auxin efflux carrier K07088 - - 0.0000000000000000000000004204 116.0
HKD1_k127_5193001_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
HKD1_k127_5193001_1 HD domain - - - 0.000000000000000000000000000000000000000000001945 183.0
HKD1_k127_5193001_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000006215 171.0
HKD1_k127_5233975_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.627e-211 675.0
HKD1_k127_5233975_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 552.0
HKD1_k127_5233975_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000004617 100.0
HKD1_k127_5237056_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 445.0
HKD1_k127_5237056_1 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000002313 154.0
HKD1_k127_5237056_2 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000001836 135.0
HKD1_k127_5237056_3 metal-sulfur cluster biosynthetic enzyme - - - 0.000000000000000000009176 102.0
HKD1_k127_5237056_4 Transglutaminase-like superfamily - - - 0.0003691 51.0
HKD1_k127_5238908_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 452.0
HKD1_k127_5238908_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000002828 60.0
HKD1_k127_5240139_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006138 268.0
HKD1_k127_5240139_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000003018 213.0
HKD1_k127_5240139_2 Cell division protein FtsQ K03589 - - 0.0000001442 61.0
HKD1_k127_5240139_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000006355 52.0
HKD1_k127_5243416_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 294.0
HKD1_k127_5243416_1 Belongs to the MraZ family K03925 - - 0.000000000000000000000000001026 120.0
HKD1_k127_5243416_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000008985 56.0
HKD1_k127_5260112_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 449.0
HKD1_k127_529137_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 549.0
HKD1_k127_5307442_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 343.0
HKD1_k127_5307442_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000002975 131.0
HKD1_k127_5307442_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000004203 144.0
HKD1_k127_5318781_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1035.0
HKD1_k127_5333737_0 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 428.0
HKD1_k127_5333737_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 426.0
HKD1_k127_5349248_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 496.0
HKD1_k127_5349248_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 390.0
HKD1_k127_5349248_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 335.0
HKD1_k127_5349248_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001293 296.0
HKD1_k127_5349248_4 Glycosyl transferase K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000002559 237.0
HKD1_k127_5349248_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000001176 208.0
HKD1_k127_5349248_6 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000006193 117.0
HKD1_k127_5349248_7 Cell division initiation protein K04074 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000001615 77.0
HKD1_k127_5349248_8 C4-type zinc ribbon domain K07164 - - 0.000009517 57.0
HKD1_k127_5357459_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 501.0
HKD1_k127_5357459_1 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000162 219.0
HKD1_k127_5365739_0 TIGRFAM PAS domain S-box - - - 0.0000000000000000000000000000000000000000000002889 184.0
HKD1_k127_5380469_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000004023 240.0
HKD1_k127_5380469_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000001285 211.0
HKD1_k127_5380469_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000002109 192.0
HKD1_k127_5380469_3 ABC-2 type transporter K09690 - - 0.0000000000000000000000000009635 123.0
HKD1_k127_5380469_4 SPFH domain-Band 7 family - - - 0.000000000000000000333 93.0
HKD1_k127_5380469_5 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000003175 95.0
HKD1_k127_5380469_6 Helix-turn-helix domain - - - 0.0001105 50.0
HKD1_k127_5413238_0 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000001335 256.0
HKD1_k127_5413238_1 - - - - 0.0000000000007641 74.0
HKD1_k127_5413238_2 - - - - 0.0000000001754 65.0
HKD1_k127_5419864_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 498.0
HKD1_k127_5419864_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 408.0
HKD1_k127_5419864_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000201 251.0
HKD1_k127_5419864_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000002646 240.0
HKD1_k127_5419864_4 FecR protein - - - 0.00000000000000000000209 108.0
HKD1_k127_5419864_5 shape-determining protein MreC K03570 - - 0.00001899 56.0
HKD1_k127_5434948_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000202 219.0
HKD1_k127_5434948_1 sugar transferase - - - 0.000000000000000000000000000000000000000009308 169.0
HKD1_k127_5436773_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000001039 199.0
HKD1_k127_5436773_1 aminotransferase class I and II - - - 0.00000000000000000000000000000005125 129.0
HKD1_k127_5436773_2 GYD domain - - - 0.000000000000000000000000000007834 125.0
HKD1_k127_5459968_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001534 184.0
HKD1_k127_5459968_2 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.00003968 56.0
HKD1_k127_5492988_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 477.0
HKD1_k127_5496359_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 455.0
HKD1_k127_5496640_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000109 226.0
HKD1_k127_551048_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 426.0
HKD1_k127_551048_1 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 272.0
HKD1_k127_551048_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000001694 175.0
HKD1_k127_551048_3 PFAM PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000001184 163.0
HKD1_k127_551048_4 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000001236 140.0
HKD1_k127_551048_5 Hfq protein - - - 0.000000000000000000000000001919 115.0
HKD1_k127_551048_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001824 54.0
HKD1_k127_5534028_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 289.0
HKD1_k127_5534028_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000004915 141.0
HKD1_k127_5534028_2 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000005164 75.0
HKD1_k127_55504_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002799 290.0
HKD1_k127_55504_1 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000001103 154.0
HKD1_k127_55504_2 - - - - 0.00000000000000000000013 102.0
HKD1_k127_5621687_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 5.909e-267 839.0
HKD1_k127_5621687_1 Belongs to the universal stress protein A family - - - 0.000000000764 66.0
HKD1_k127_5638710_0 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 521.0
HKD1_k127_5638710_1 L-malate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000008988 182.0
HKD1_k127_5638710_2 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000006247 144.0
HKD1_k127_5638710_3 Transglycosylase associated protein - - - 0.00000000000000000000000006914 108.0
HKD1_k127_5655580_0 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000001146 176.0
HKD1_k127_5655580_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000001266 175.0
HKD1_k127_5708234_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 258.0
HKD1_k127_5708234_1 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000001328 176.0
HKD1_k127_5708234_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000005925 70.0
HKD1_k127_580210_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 3.953e-199 632.0
HKD1_k127_590523_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 364.0
HKD1_k127_590523_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000009221 230.0
HKD1_k127_590523_2 B12 binding domain K14084 - - 0.000000000000000000000000000000000000000000000000000000002476 208.0
HKD1_k127_6039829_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 394.0
HKD1_k127_6039829_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000001959 174.0
HKD1_k127_6039829_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000005613 170.0
HKD1_k127_6039829_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000006157 141.0
HKD1_k127_6039829_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000006663 134.0
HKD1_k127_6039829_5 Could be involved in septation K06412 - - 0.000000000000000000001633 98.0
HKD1_k127_6052966_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 518.0
HKD1_k127_6052966_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000235 278.0
HKD1_k127_6052966_2 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000001431 216.0
HKD1_k127_6052966_3 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000006666 204.0
HKD1_k127_6052966_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000003399 119.0
HKD1_k127_6059223_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 389.0
HKD1_k127_6059223_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 241.0
HKD1_k127_6059223_2 ferric iron binding K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000008764 182.0
HKD1_k127_6059223_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000006288 111.0
HKD1_k127_6059223_4 Transcription factor zinc-finger K09981 - - 0.0000003609 56.0
HKD1_k127_6061507_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 463.0
HKD1_k127_6061507_1 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 358.0
HKD1_k127_6061507_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000005061 228.0
HKD1_k127_6061507_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000003351 109.0
HKD1_k127_6078185_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000841 177.0
HKD1_k127_6078185_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000008339 176.0
HKD1_k127_6078185_2 Tetratricopeptide repeat - - - 0.000000002929 60.0
HKD1_k127_6078185_3 - - - - 0.00000002507 64.0
HKD1_k127_6086958_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 585.0
HKD1_k127_6086958_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000005124 147.0
HKD1_k127_6094987_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000001289 233.0
HKD1_k127_6094987_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
HKD1_k127_6094987_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000004629 68.0
HKD1_k127_6121944_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 376.0
HKD1_k127_6121944_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000003321 175.0
HKD1_k127_6128440_0 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 463.0
HKD1_k127_6128440_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008865 266.0
HKD1_k127_6128440_2 - - - - 0.0000000000000000000000023 106.0
HKD1_k127_6147378_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 469.0
HKD1_k127_6147378_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 435.0
HKD1_k127_6147378_2 vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0000000000005231 77.0
HKD1_k127_6148269_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000004523 153.0
HKD1_k127_6148269_1 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000000000000000000000000001537 154.0
HKD1_k127_6166330_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000001264 151.0
HKD1_k127_6166330_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000001451 81.0
HKD1_k127_6175573_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.904e-245 772.0
HKD1_k127_6175573_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000003317 188.0
HKD1_k127_6175573_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000001764 173.0
HKD1_k127_6175573_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000009858 116.0
HKD1_k127_6175573_4 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000005166 108.0
HKD1_k127_6175573_5 Iron-sulfur cluster assembly protein K03593 - - 0.00000000000000000000002009 104.0
HKD1_k127_6175754_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 304.0
HKD1_k127_6175754_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 286.0
HKD1_k127_6175754_2 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000328 184.0
HKD1_k127_6182955_0 PFAM Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 349.0
HKD1_k127_6185317_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000008579 224.0
HKD1_k127_6221396_0 spore germination - - - 0.0000000000000000000000000001454 123.0
HKD1_k127_6221396_1 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000203 115.0
HKD1_k127_6221396_2 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000006171 98.0
HKD1_k127_6231924_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
HKD1_k127_6231924_1 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000001487 166.0
HKD1_k127_6244961_0 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008118 264.0
HKD1_k127_6267039_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 316.0
HKD1_k127_6267039_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000001575 124.0
HKD1_k127_6267039_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000009 108.0
HKD1_k127_6320744_0 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
HKD1_k127_6320744_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 316.0
HKD1_k127_6320744_2 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000003055 250.0
HKD1_k127_6357107_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
HKD1_k127_6357107_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 305.0
HKD1_k127_6357107_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000625 279.0
HKD1_k127_6357107_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002127 257.0
HKD1_k127_6357107_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
HKD1_k127_6357107_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000009009 194.0
HKD1_k127_6357107_6 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000003853 190.0
HKD1_k127_6357107_7 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001041 171.0
HKD1_k127_6357107_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000003262 138.0
HKD1_k127_6357107_9 cellulose binding - - - 0.0000000000000000000000000000005655 136.0
HKD1_k127_6367682_0 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 469.0
HKD1_k127_6367682_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 454.0
HKD1_k127_6367682_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 321.0
HKD1_k127_6367682_3 Fe-S protein K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 297.0
HKD1_k127_6367682_4 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003047 304.0
HKD1_k127_6367682_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001155 198.0
HKD1_k127_6367682_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000001022 97.0
HKD1_k127_6367682_7 - - - - 0.0000000002491 71.0
HKD1_k127_6445245_0 COG0515 Serine threonine protein kinase - - - 0.0000000000000000000000000000005303 141.0
HKD1_k127_6464377_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002561 259.0
HKD1_k127_6464377_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000002123 215.0
HKD1_k127_6464377_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000004754 154.0
HKD1_k127_6464377_3 Protein of unknown function (DUF1109) - - - 0.000003412 57.0
HKD1_k127_6488932_0 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 311.0
HKD1_k127_6488932_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008306 281.0
HKD1_k127_6578285_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 621.0
HKD1_k127_6578285_1 - - - - 0.0000979 51.0
HKD1_k127_6587196_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 527.0
HKD1_k127_6592437_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 333.0
HKD1_k127_6592437_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009856 265.0
HKD1_k127_6592437_2 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000001329 181.0
HKD1_k127_6592437_3 oligopeptide transport K03305 - - 0.0000000002832 65.0
HKD1_k127_6634117_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 2.991e-205 671.0
HKD1_k127_6634117_1 response regulator - - - 0.000000000000000000000000001524 116.0
HKD1_k127_6634117_2 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000005123 118.0
HKD1_k127_6634117_3 Histidine kinase - - - 0.000000000000000000004648 107.0
HKD1_k127_6693673_0 nuclear chromosome segregation - - - 0.0000000005575 69.0
HKD1_k127_6701706_0 PFAM Peptidase M23 - - - 0.0000000000000000000000009535 113.0
HKD1_k127_6701706_1 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000299 96.0
HKD1_k127_6701706_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00007327 51.0
HKD1_k127_67018_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 612.0
HKD1_k127_67018_1 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 331.0
HKD1_k127_67018_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002576 279.0
HKD1_k127_67018_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000007348 178.0
HKD1_k127_6705415_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 377.0
HKD1_k127_6705415_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000005221 248.0
HKD1_k127_6705415_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000003359 155.0
HKD1_k127_6705415_3 mitochondrial electron transport, NADH to ubiquinone K10353 - 2.7.1.76 0.0000000000000000000000000000000003709 134.0
HKD1_k127_6705415_4 DNA mismatch repair protein MutT - - - 0.0000000000000000000000000000002555 130.0
HKD1_k127_6705415_5 peptidyl-tyrosine sulfation - - - 0.00005725 55.0
HKD1_k127_6709840_0 PFAM ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 333.0
HKD1_k127_6709840_1 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000001758 166.0
HKD1_k127_6709840_2 Bacterial membrane protein YfhO - - - 0.000007143 57.0
HKD1_k127_6725122_0 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000007326 72.0
HKD1_k127_6753466_0 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000003506 239.0
HKD1_k127_6753466_1 carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000007574 184.0
HKD1_k127_688753_0 Adenylate and Guanylate cyclase catalytic domain - - - 2.603e-317 994.0
HKD1_k127_6919792_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 460.0
HKD1_k127_6919792_1 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000006991 111.0
HKD1_k127_6919792_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000003312 104.0
HKD1_k127_6919792_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000004616 83.0
HKD1_k127_6995686_0 Domain of unknown function (DUF1956) - - - 0.000000000000000000000000000271 123.0
HKD1_k127_6995686_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000001739 65.0
HKD1_k127_6995686_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000007594 58.0
HKD1_k127_7049824_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 399.0
HKD1_k127_7049824_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 357.0
HKD1_k127_7049824_2 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000001311 245.0
HKD1_k127_7049824_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000001013 193.0
HKD1_k127_7049824_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000001891 173.0
HKD1_k127_7049824_5 PAS fold K07636 - 2.7.13.3 0.00000000000000000000000000000000344 146.0
HKD1_k127_7049824_6 Protein of unknown function (DUF2914) - - - 0.00000000000000000001934 95.0
HKD1_k127_7066179_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 516.0
HKD1_k127_7066179_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 291.0
HKD1_k127_7066179_10 Phospholipase B - - - 0.00000000000000279 89.0
HKD1_k127_7066179_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000002998 49.0
HKD1_k127_7066179_2 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002147 274.0
HKD1_k127_7066179_3 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000001607 177.0
HKD1_k127_7066179_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000001074 171.0
HKD1_k127_7066179_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000004723 159.0
HKD1_k127_7066179_6 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000001815 163.0
HKD1_k127_7066179_7 YsiA-like protein, C-terminal region K13770 - - 0.0000000000000000000000000000000000000003955 156.0
HKD1_k127_7066179_8 peptidase S16 K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000004883 119.0
HKD1_k127_7066179_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000002641 108.0
HKD1_k127_7071391_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 391.0
HKD1_k127_7071391_1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 301.0
HKD1_k127_7071391_2 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002732 277.0
HKD1_k127_7071391_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000001471 83.0
HKD1_k127_7071391_4 Outer membrane protein (OmpH-like) K06142 - - 0.0000000003372 68.0
HKD1_k127_7078110_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.177e-220 689.0
HKD1_k127_7078110_1 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000569 147.0
HKD1_k127_7078110_2 Tricorn protease homolog K08676 - - 0.000008183 49.0
HKD1_k127_71012_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 503.0
HKD1_k127_71012_1 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 333.0
HKD1_k127_71012_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 307.0
HKD1_k127_71012_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002892 262.0
HKD1_k127_71012_4 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K00156,K01652 - 1.2.5.1,2.2.1.6 0.00000000000000000000000000001494 122.0
HKD1_k127_71012_5 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000009357 121.0
HKD1_k127_71012_6 - - - - 0.00000000000000000000006319 106.0
HKD1_k127_7109203_0 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 351.0
HKD1_k127_7109203_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 295.0
HKD1_k127_7109203_2 Ion channel - - - 0.0000000000000000006234 92.0
HKD1_k127_7112378_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 306.0
HKD1_k127_7112378_1 ABC transporter K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000004913 236.0
HKD1_k127_7112378_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000001298 114.0
HKD1_k127_7112378_3 protein kinase activity - - - 0.0000000000002166 82.0
HKD1_k127_7112378_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000001535 78.0
HKD1_k127_7112378_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0001242 53.0
HKD1_k127_7117347_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 304.0
HKD1_k127_7117347_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 297.0
HKD1_k127_7117347_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000001001 109.0
HKD1_k127_7117347_3 Biotin-requiring enzyme - - - 0.0000000000000003219 92.0
HKD1_k127_7132968_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000436 289.0
HKD1_k127_7138455_0 oxidoreductase - - - 0.000000000000000000000000000000000003309 141.0
HKD1_k127_7138455_1 PA14 - - - 0.00000000002138 77.0
HKD1_k127_7141842_0 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 361.0
HKD1_k127_7141842_1 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 309.0
HKD1_k127_7141842_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000002862 200.0
HKD1_k127_7141842_3 peptidyl-tyrosine sulfation - - - 0.000000001837 72.0
HKD1_k127_7169618_0 transposase mutator type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 526.0
HKD1_k127_7169618_1 DNA excision - - - 0.00003002 48.0
HKD1_k127_7183520_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 395.0
HKD1_k127_7185127_0 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000007754 181.0
HKD1_k127_7185127_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000001773 73.0
HKD1_k127_7185127_2 Histidine kinase - - - 0.0003111 52.0
HKD1_k127_7195849_0 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 331.0
HKD1_k127_7195849_1 Addiction module toxin, Txe YoeB - - - 0.0000000000000000000000002189 105.0
HKD1_k127_7229964_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.611e-265 844.0
HKD1_k127_7229964_1 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 280.0
HKD1_k127_7229964_2 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000001968 153.0
HKD1_k127_7255974_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 271.0
HKD1_k127_7255974_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
HKD1_k127_727464_0 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 312.0
HKD1_k127_727464_1 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000003513 168.0
HKD1_k127_727464_2 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000008747 137.0
HKD1_k127_727464_3 DRTGG domain protein - - - 0.0000000000000000000000006745 109.0
HKD1_k127_727464_4 NADH dehydrogenase K00335 - 1.6.5.3 0.0000000000000005467 83.0
HKD1_k127_727464_6 DRTGG domain - - - 0.00000007956 58.0
HKD1_k127_7277453_0 Mannitol dehydrogenase Rossmann domain K00040,K00045 - 1.1.1.57,1.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
HKD1_k127_7277453_1 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000004088 247.0
HKD1_k127_7277453_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000006516 51.0
HKD1_k127_7283699_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 433.0
HKD1_k127_7283699_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 331.0
HKD1_k127_7283699_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002306 274.0
HKD1_k127_7283699_3 Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000002418 181.0
HKD1_k127_7283699_4 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000001015 124.0
HKD1_k127_7283699_5 - - - - 0.000000000000000000000656 104.0
HKD1_k127_7283699_6 transcriptional regulator - - - 0.000005616 57.0
HKD1_k127_7296021_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005339 235.0
HKD1_k127_7300682_0 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 413.0
HKD1_k127_7300682_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003876 236.0
HKD1_k127_7300682_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000004391 111.0
HKD1_k127_7310433_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 406.0
HKD1_k127_7310433_1 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 316.0
HKD1_k127_7310433_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
HKD1_k127_7310433_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000003197 194.0
HKD1_k127_7324137_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002581 258.0
HKD1_k127_7357270_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 514.0
HKD1_k127_7357270_1 glyoxalase III activity - - - 0.00000000000000000000000000000002745 131.0
HKD1_k127_7357270_2 - - - - 0.000000000000000000000004867 105.0
HKD1_k127_7358804_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 546.0
HKD1_k127_7358804_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003872 276.0
HKD1_k127_7358804_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001525 273.0
HKD1_k127_7358804_3 membrane - - - 0.000000000000000000000000000000000000000000000006653 186.0
HKD1_k127_7358804_4 LytTr DNA-binding domain - - - 0.0000000000000000000001569 98.0
HKD1_k127_7358804_5 - K01992 - - 0.00000000000000001542 89.0
HKD1_k127_7359492_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 301.0
HKD1_k127_7359492_1 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
HKD1_k127_7359492_2 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000001438 155.0
HKD1_k127_7359492_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000001963 110.0
HKD1_k127_7371706_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 452.0
HKD1_k127_7371706_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000008481 253.0
HKD1_k127_7371706_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000001194 156.0
HKD1_k127_7397001_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000001883 256.0
HKD1_k127_7397001_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000006648 192.0
HKD1_k127_7397001_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000005216 64.0
HKD1_k127_7459179_0 GMC oxidoreductase K03333 - 1.1.3.6 1.614e-195 626.0
HKD1_k127_7459179_1 Aldehyde dehydrogenase family K00129 - 1.2.1.5 0.0000000000000000000000000000000002953 135.0
HKD1_k127_7459179_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000006366 108.0
HKD1_k127_7479774_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001639 247.0
HKD1_k127_7479774_1 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000002797 199.0
HKD1_k127_7479774_2 Sodium:solute symporter family K03307,K11928 - - 0.00000000000000000000000000000000000001915 160.0
HKD1_k127_7523280_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000003725 149.0
HKD1_k127_7523280_1 transcription factor binding - - - 0.000000000000000000000000000000000288 137.0
HKD1_k127_7523280_2 Protein of unknown function (DUF2723) - - - 0.00000000000000007531 96.0
HKD1_k127_7523280_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000003315 59.0
HKD1_k127_7523280_4 General transcription factor 3C polypeptide K15201 - - 0.0005955 49.0
HKD1_k127_7588868_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 457.0
HKD1_k127_7588868_1 5' nucleotidase family - - - 0.0000000000000000000355 91.0
HKD1_k127_7632819_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002252 253.0
HKD1_k127_7632819_1 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000001373 131.0
HKD1_k127_7633625_0 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 565.0
HKD1_k127_7633625_1 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000001737 89.0
HKD1_k127_7648222_0 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000005696 142.0
HKD1_k127_7648222_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000001755 107.0
HKD1_k127_7657225_0 TonB-dependent receptor plug K16092 - - 0.000000000000000000000006637 113.0
HKD1_k127_7657225_1 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000006605 99.0
HKD1_k127_7657225_2 Protein of unknown function (DUF1573) - - - 0.000000000000000004077 96.0
HKD1_k127_7660759_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 492.0
HKD1_k127_7660759_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 278.0
HKD1_k127_7660759_2 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000001532 234.0
HKD1_k127_7660759_3 Dimerisation domain - - - 0.000000000000000000000000000000000000000000002101 177.0
HKD1_k127_7660759_4 - - - - 0.000000000000000000001719 107.0
HKD1_k127_7660759_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000002373 79.0
HKD1_k127_7673165_0 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000008922 169.0
HKD1_k127_7673165_1 Belongs to the BshC family K22136 - - 0.00000001376 65.0
HKD1_k127_7697361_0 Alg9-like mannosyltransferase family K05286 - - 0.00000000001886 76.0
HKD1_k127_7711226_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001724 244.0
HKD1_k127_7711226_1 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000004107 157.0
HKD1_k127_7711226_2 positive regulation of growth rate - - - 0.0000000000000000000000000000000000001434 157.0
HKD1_k127_7711226_3 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000002469 136.0
HKD1_k127_7711226_4 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000003411 102.0
HKD1_k127_7711226_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000002119 89.0
HKD1_k127_7711226_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.000000000003488 68.0
HKD1_k127_7711226_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000006201 51.0
HKD1_k127_7711226_8 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0004205 51.0
HKD1_k127_7711226_9 PFAM response regulator receiver - - - 0.0004861 48.0
HKD1_k127_7734717_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005315 261.0
HKD1_k127_7734717_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000003883 214.0
HKD1_k127_7734717_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000001795 188.0
HKD1_k127_7744967_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000005917 225.0
HKD1_k127_7744967_1 Transposase K07481 - - 0.0000003145 58.0
HKD1_k127_7783128_0 carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 443.0
HKD1_k127_7811212_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 428.0
HKD1_k127_7811212_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 395.0
HKD1_k127_7811212_2 4Fe-4S binding domain - - - 0.000000000000000000000000000001591 122.0
HKD1_k127_7811212_3 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000004076 116.0
HKD1_k127_7811212_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000005251 115.0
HKD1_k127_7814972_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 383.0
HKD1_k127_7814972_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 351.0
HKD1_k127_7814972_2 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 338.0
HKD1_k127_7814972_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000005231 242.0
HKD1_k127_7814972_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000001359 199.0
HKD1_k127_7814972_5 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.0000000000000000000000000000000000000000000000003864 195.0
HKD1_k127_7814972_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000002173 171.0
HKD1_k127_7814972_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000002018 115.0
HKD1_k127_7829272_0 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000002337 196.0
HKD1_k127_7829272_1 geranylgeranyl reductase activity - - - 0.000001403 57.0
HKD1_k127_7833644_0 Cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 289.0
HKD1_k127_7833644_2 transposition - - - 0.00000000001324 77.0
HKD1_k127_7835074_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
HKD1_k127_7835074_1 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000001444 121.0
HKD1_k127_7835074_2 nitrate reductase activity - - - 0.0000000000000000000004587 105.0
HKD1_k127_7941594_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.02e-215 687.0
HKD1_k127_834806_0 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008277 287.0
HKD1_k127_834806_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000001786 196.0
HKD1_k127_892526_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 5.892e-237 749.0
HKD1_k127_892526_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 316.0
HKD1_k127_892526_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000007817 250.0
HKD1_k127_892526_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000006304 245.0
HKD1_k127_892526_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001126 228.0
HKD1_k127_892526_5 O-Antigen ligase K18814 - - 0.00000000000000000000000000000006692 139.0
HKD1_k127_892526_6 Glycosyl-hydrolase 97 N-terminal - - - 0.000000000002895 81.0
HKD1_k127_892526_7 Belongs to the UPF0434 family K09791 - - 0.000000000005559 68.0
HKD1_k127_892526_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001424 59.0