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Overview

ID MAG01730
Name HKD1_bin.48
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Polyangiales
Family Polyangiaceae
Genus
Species
Assembly information
Completeness (%) 74.17
Contamination (%) 3.07
GC content (%) 66.0
N50 (bp) 8,604
Genome size (bp) 6,247,722

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4840

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1000538_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 388.0
HKD1_k127_1000538_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 323.0
HKD1_k127_1000538_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000915 182.0
HKD1_k127_1005257_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 5.424e-214 685.0
HKD1_k127_1005257_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 442.0
HKD1_k127_1005257_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000008741 69.0
HKD1_k127_1005257_3 Glycosyltransferase family 87 - - - 0.00001121 57.0
HKD1_k127_1008469_0 Belongs to the glycosyl hydrolase 13 family - - - 2.312e-216 695.0
HKD1_k127_1008469_1 PFAM YcfA-like protein - - - 0.0000000000144 67.0
HKD1_k127_1008469_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000007288 66.0
HKD1_k127_1008469_3 Domain of unknown function (DUF4920) - - - 0.00007975 52.0
HKD1_k127_1008469_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0002187 46.0
HKD1_k127_101239_0 Tetratricopeptide repeat - - - 2.48e-264 842.0
HKD1_k127_101239_1 Domain of unknown function (DUF4132) - - - 7.127e-237 786.0
HKD1_k127_101239_2 serine-type endopeptidase activity K07261 - - 0.000000000000000000000000000000000000000000000000000000007807 205.0
HKD1_k127_101239_3 Family membership - - - 0.0000000000000000000000003834 114.0
HKD1_k127_101239_4 Photosynthesis system II assembly factor YCF48 - - - 0.00002058 59.0
HKD1_k127_1016967_0 nitrite reductase [NAD(P)H] activity K00493,K07408,K15762 - 1.14.14.1 3.769e-215 688.0
HKD1_k127_1016967_1 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 605.0
HKD1_k127_1016967_10 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.00000000002847 69.0
HKD1_k127_1016967_2 DNA-binding response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 584.0
HKD1_k127_1016967_3 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 553.0
HKD1_k127_1016967_4 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 469.0
HKD1_k127_1016967_5 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 387.0
HKD1_k127_1016967_6 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000005726 169.0
HKD1_k127_1016967_7 - - - - 0.000000000000000000000000000000000003645 145.0
HKD1_k127_1016967_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003989 132.0
HKD1_k127_1016967_9 cheY-homologous receiver domain - - - 0.000000000000000000811 94.0
HKD1_k127_1017838_0 Tetratricopeptide repeat - - - 1.724e-253 816.0
HKD1_k127_1017838_1 Tetratricopeptide repeat - - - 7.326e-214 701.0
HKD1_k127_1017838_10 PilZ domain - - - 0.00000000000000000000000000000000000000004677 155.0
HKD1_k127_1017838_11 - - - - 0.00000000000000000000000000000000000000751 152.0
HKD1_k127_1017838_13 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00007625 55.0
HKD1_k127_1017838_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 591.0
HKD1_k127_1017838_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 569.0
HKD1_k127_1017838_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 362.0
HKD1_k127_1017838_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001486 281.0
HKD1_k127_1017838_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007707 271.0
HKD1_k127_1017838_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001911 288.0
HKD1_k127_1017838_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001532 256.0
HKD1_k127_1017838_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000003033 186.0
HKD1_k127_1020256_0 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000002586 150.0
HKD1_k127_1020256_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000002962 129.0
HKD1_k127_1020256_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000001136 104.0
HKD1_k127_1021208_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1353.0
HKD1_k127_1021208_1 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 439.0
HKD1_k127_1021208_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
HKD1_k127_1021208_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 311.0
HKD1_k127_1021208_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000261 206.0
HKD1_k127_1021208_5 protein trimerization - - - 0.0000000000000000000000000000000000000000001124 177.0
HKD1_k127_1021208_6 Tetratricopeptide repeat - - - 0.000000003439 68.0
HKD1_k127_1039096_0 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
HKD1_k127_1039096_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 454.0
HKD1_k127_1039096_10 PFAM Formylglycine-generating sulfatase enzyme K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000001568 179.0
HKD1_k127_1039096_11 Belongs to the peptidase S1B family K01318 - 3.4.21.19 0.0000000000000000000000000000000001097 149.0
HKD1_k127_1039096_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000001735 64.0
HKD1_k127_1039096_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 279.0
HKD1_k127_1039096_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004568 269.0
HKD1_k127_1039096_4 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005682 276.0
HKD1_k127_1039096_5 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000816 225.0
HKD1_k127_1039096_6 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000003059 218.0
HKD1_k127_1039096_7 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000006687 213.0
HKD1_k127_1039096_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000004182 198.0
HKD1_k127_1039096_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001693 184.0
HKD1_k127_104070_0 synthase K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 358.0
HKD1_k127_104070_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006546 265.0
HKD1_k127_104070_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000002227 236.0
HKD1_k127_104070_3 Belongs to the enoyl-CoA hydratase isomerase family K15313 - - 0.000000000000000000000000000000000000000000000000000000000008987 226.0
HKD1_k127_104070_4 Enoyl-CoA hydratase K13779,K15312 - 4.2.1.57 0.00000000000000000002022 105.0
HKD1_k127_104070_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K15337 - - 0.000000000000006644 84.0
HKD1_k127_104070_6 cytochrome oxidase assembly K02259 GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840 - 0.000001558 55.0
HKD1_k127_1048273_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.204e-215 692.0
HKD1_k127_1048273_1 - - - - 0.00000000000000178 83.0
HKD1_k127_1048273_2 - - - - 0.0000000007539 64.0
HKD1_k127_1050727_0 Thioredoxin - - - 4.364e-225 717.0
HKD1_k127_1050727_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 590.0
HKD1_k127_1050727_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000004247 134.0
HKD1_k127_1050727_3 protein conserved in cyanobacteria - - - 0.000000000000000000000000000003502 124.0
HKD1_k127_1050727_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000235 76.0
HKD1_k127_1063414_0 Putative glutamine amidotransferase - - - 1.889e-203 655.0
HKD1_k127_1063414_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 515.0
HKD1_k127_1063414_11 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000001309 72.0
HKD1_k127_1063414_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 510.0
HKD1_k127_1063414_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 429.0
HKD1_k127_1063414_4 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008979 291.0
HKD1_k127_1063414_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003381 267.0
HKD1_k127_1063414_7 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000004587 201.0
HKD1_k127_1063414_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000001154 107.0
HKD1_k127_1073388_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 290.0
HKD1_k127_1073388_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
HKD1_k127_1073388_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000004897 176.0
HKD1_k127_1073388_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000003271 118.0
HKD1_k127_1073388_4 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000002153 118.0
HKD1_k127_1073388_5 Leucine carboxyl methyltransferase - - - 0.00000000000000000000387 107.0
HKD1_k127_1073388_6 Stigma-specific protein, Stig1 - - - 0.0000000000000003811 90.0
HKD1_k127_1073388_9 Domain of unknown function (DUF1877) - - - 0.0005679 45.0
HKD1_k127_1073648_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 593.0
HKD1_k127_1073648_1 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 510.0
HKD1_k127_1073648_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 362.0
HKD1_k127_1073648_3 electron transfer activity K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
HKD1_k127_1073648_4 - - - - 0.0000000000000000000000000000000000000000000000000000003681 200.0
HKD1_k127_1073648_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000002981 115.0
HKD1_k127_1073648_6 DsrE/DsrF/DrsH-like family - - - 0.00000000003128 64.0
HKD1_k127_1088957_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000534 234.0
HKD1_k127_1088957_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000005238 237.0
HKD1_k127_1088957_2 PLD-like domain - - - 0.0000000000000000000000000000000000000000000002566 184.0
HKD1_k127_1088957_3 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000006331 136.0
HKD1_k127_1088957_4 AAA domain - - - 0.000000000000000000000000000004995 130.0
HKD1_k127_1088957_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000003378 118.0
HKD1_k127_1088957_6 Universal stress protein - - - 0.0000000000008819 77.0
HKD1_k127_1088957_7 - - - - 0.0000002392 61.0
HKD1_k127_1114004_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 400.0
HKD1_k127_1114004_1 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 318.0
HKD1_k127_1114004_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000004545 193.0
HKD1_k127_1114004_3 - - - - 0.000000000000000000000000000000000000003393 168.0
HKD1_k127_1114004_4 PEGA domain - - - 0.000000000000000000000000000000001193 136.0
HKD1_k127_1114004_5 FHA domain - - - 0.0000000000000000000000000004943 127.0
HKD1_k127_1114601_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 594.0
HKD1_k127_1114601_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 418.0
HKD1_k127_1114601_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 390.0
HKD1_k127_1114601_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 311.0
HKD1_k127_1114601_4 DMT(Drug metabolite transporter) superfamily permease - - - 0.000000000000000000000000000000000001293 148.0
HKD1_k127_1114601_5 Peptidase M50 - - - 0.0000000007245 68.0
HKD1_k127_1114601_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000005542 65.0
HKD1_k127_1114601_7 - - - - 0.000249 53.0
HKD1_k127_1128926_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 574.0
HKD1_k127_1128926_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 497.0
HKD1_k127_1128926_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 419.0
HKD1_k127_1128926_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 271.0
HKD1_k127_1128926_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000004616 230.0
HKD1_k127_1141316_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 1.763e-236 738.0
HKD1_k127_1141316_1 Reductase C-terminal K05297 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 633.0
HKD1_k127_1141316_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 626.0
HKD1_k127_1141316_3 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 551.0
HKD1_k127_1141316_5 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000000000000008401 177.0
HKD1_k127_1141316_6 - - - - 0.00000000000000000000000000000000000000000000001804 175.0
HKD1_k127_1141316_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001033 168.0
HKD1_k127_1143761_0 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
HKD1_k127_1143761_1 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000002755 229.0
HKD1_k127_1143761_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001011 206.0
HKD1_k127_1143761_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.000000000000000000000000000000000000000000000000001125 196.0
HKD1_k127_1143761_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000002261 63.0
HKD1_k127_1149979_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 448.0
HKD1_k127_1149979_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 342.0
HKD1_k127_1149979_2 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 329.0
HKD1_k127_1149979_3 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
HKD1_k127_1149979_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 278.0
HKD1_k127_1149979_5 - - - - 0.00000000000000000000000008426 109.0
HKD1_k127_1149979_6 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000001052 101.0
HKD1_k127_1172138_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 426.0
HKD1_k127_1172819_0 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 410.0
HKD1_k127_1172819_1 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000009905 223.0
HKD1_k127_1172819_2 Cytochrome c - - - 0.0000000000000000000000000000009575 140.0
HKD1_k127_1173233_0 Zinc finger, swim domain protein - - - 1.128e-216 708.0
HKD1_k127_1173233_1 WD domain- G-beta repeat PBS lyase HEAT-like K03497 - - 0.0000000000000000000000000000000000000000000000000000003123 209.0
HKD1_k127_1174798_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 445.0
HKD1_k127_1174798_1 metal cluster binding - - - 0.00000000000000000000000000000000000000000000005073 175.0
HKD1_k127_1174798_2 - - - - 0.00000000000000000001047 102.0
HKD1_k127_1174798_3 amine dehydrogenase activity - - - 0.0000000000000000005914 94.0
HKD1_k127_1174798_4 Stigma-specific protein, Stig1 - - - 0.00000000000000002305 89.0
HKD1_k127_1174798_5 Trypsin-like serine protease - - - 0.0000000001121 70.0
HKD1_k127_1183579_0 HAD-superfamily phosphatase subfamily IIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 459.0
HKD1_k127_1183579_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 371.0
HKD1_k127_1183579_2 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 380.0
HKD1_k127_1183579_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 361.0
HKD1_k127_1183579_4 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 317.0
HKD1_k127_1183579_5 lipopolysaccharide N-acetylmannosaminouronosyltransferase activity K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000006995 254.0
HKD1_k127_1183579_6 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000006143 247.0
HKD1_k127_1183579_8 Maltose acetyltransferase K00661 - 2.3.1.79 0.000000000000001443 92.0
HKD1_k127_1183698_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 436.0
HKD1_k127_1183698_1 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 406.0
HKD1_k127_1183698_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 356.0
HKD1_k127_1183698_3 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.0000000000000000000000000000000000000000000000001854 190.0
HKD1_k127_1183698_4 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.0000000000000000000000000000000001369 145.0
HKD1_k127_1183698_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000001224 109.0
HKD1_k127_1183698_7 amine dehydrogenase activity - - - 0.000002212 60.0
HKD1_k127_1188245_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 349.0
HKD1_k127_1188245_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 340.0
HKD1_k127_1188245_2 protein trimerization - - - 0.00000000000000000000000000000000000000000000000006123 197.0
HKD1_k127_1188245_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000003408 72.0
HKD1_k127_1188245_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000001608 63.0
HKD1_k127_1197933_0 ABC transporter, ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 408.0
HKD1_k127_1197933_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 352.0
HKD1_k127_1197933_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 355.0
HKD1_k127_1211661_0 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004651 280.0
HKD1_k127_1211661_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000005723 161.0
HKD1_k127_1211661_2 helix_turn_helix, mercury resistance - - - 0.000000000000000000000001183 118.0
HKD1_k127_1211661_3 Cupin domain - - - 0.00000000000004407 78.0
HKD1_k127_1211661_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K12287,K13276 - 3.2.1.4 0.0000000007962 72.0
HKD1_k127_1211661_5 Esterase PHB depolymerase K03932 - - 0.0000002343 60.0
HKD1_k127_1243944_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.487e-284 898.0
HKD1_k127_1243944_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 308.0
HKD1_k127_1243944_2 Predicted membrane protein (DUF2254) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 - 0.000000000000000000815 91.0
HKD1_k127_1243944_3 phosphate-selective porin O and P - - - 0.00007591 56.0
HKD1_k127_1304657_0 DEAD/DEAH box helicase K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.315e-261 828.0
HKD1_k127_1304657_1 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 553.0
HKD1_k127_1304657_2 tRNA cytidylyltransferase activity - - - 0.000000000000000000000000000000000000001384 156.0
HKD1_k127_1325010_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001242 269.0
HKD1_k127_1325010_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000001118 149.0
HKD1_k127_1325010_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000001197 110.0
HKD1_k127_1350753_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 617.0
HKD1_k127_1350753_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 400.0
HKD1_k127_1350753_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 357.0
HKD1_k127_1350753_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 343.0
HKD1_k127_1350753_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000002067 171.0
HKD1_k127_1350753_5 GAF domain - - - 0.000000000000000000000000000000000000000009743 170.0
HKD1_k127_1350753_6 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000008758 118.0
HKD1_k127_1353359_0 ERAP1-like C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 526.0
HKD1_k127_1353359_1 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 368.0
HKD1_k127_1353359_2 Phospholipase D Transphosphatidylase - - - 0.00000000000000000000000000000001634 140.0
HKD1_k127_1353359_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000007632 116.0
HKD1_k127_1353359_4 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.0000000000000000000000001484 119.0
HKD1_k127_1353359_5 - - - - 0.0000000000004767 79.0
HKD1_k127_1360544_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2310.0
HKD1_k127_1360544_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 587.0
HKD1_k127_1360544_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000001465 171.0
HKD1_k127_1360544_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001935 94.0
HKD1_k127_1364088_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 452.0
HKD1_k127_1364088_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 436.0
HKD1_k127_1364088_2 regulatory protein, tetR - - - 0.000000000000000000000000000000000001532 147.0
HKD1_k127_1364088_3 - - - - 0.0000000000000007321 87.0
HKD1_k127_1372376_0 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002328 276.0
HKD1_k127_1372376_1 EVE domain - - - 0.00000000000000000000000000000000000000001983 156.0
HKD1_k127_1372376_2 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0004857,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009636,GO:0009987,GO:0010496,GO:0010497,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0030234,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0097237,GO:0098754,GO:0098772,GO:0098869,GO:1990748 - 0.00000000000006426 83.0
HKD1_k127_1372376_3 fatty acid desaturase - - - 0.0001535 55.0
HKD1_k127_1376299_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 4.905e-211 662.0
HKD1_k127_1376299_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 323.0
HKD1_k127_1376299_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 319.0
HKD1_k127_1376299_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 291.0
HKD1_k127_1376299_4 alpha/beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000000000000000001422 154.0
HKD1_k127_1376299_5 Trypsin-like peptidase domain - - - 0.0000000000000000000000008262 115.0
HKD1_k127_1376299_6 - - - - 0.00000000005635 65.0
HKD1_k127_1399863_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.791e-205 654.0
HKD1_k127_1399863_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 582.0
HKD1_k127_1399863_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 473.0
HKD1_k127_1399863_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 335.0
HKD1_k127_1399863_4 calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.00005369 56.0
HKD1_k127_1403340_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 9.022e-224 712.0
HKD1_k127_1403340_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000183 214.0
HKD1_k127_1403340_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001009 192.0
HKD1_k127_1403340_3 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000001077 117.0
HKD1_k127_1403340_4 structural constituent of cuticle K19721 - - 0.000000000001471 79.0
HKD1_k127_1403340_5 Nucleotidyltransferase domain - - - 0.0000000001224 74.0
HKD1_k127_1403340_7 Family membership K12132 - 2.7.11.1 0.00001161 56.0
HKD1_k127_1403340_8 Nucleotidyltransferase domain - - - 0.0002006 48.0
HKD1_k127_140825_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1080.0
HKD1_k127_140825_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000147 121.0
HKD1_k127_140825_2 Tetratricopeptide repeat - - - 0.00000000000000000000007012 117.0
HKD1_k127_1408490_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 348.0
HKD1_k127_1408490_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 295.0
HKD1_k127_1408490_2 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000007236 200.0
HKD1_k127_1408490_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001297 208.0
HKD1_k127_1408490_4 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000214 170.0
HKD1_k127_1408490_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000008702 80.0
HKD1_k127_1408675_0 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 536.0
HKD1_k127_1408675_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 434.0
HKD1_k127_1408675_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005013 289.0
HKD1_k127_1408675_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000001642 215.0
HKD1_k127_1408675_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000001835 173.0
HKD1_k127_1408675_5 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000002188 152.0
HKD1_k127_1408675_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000004109 107.0
HKD1_k127_1408675_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000003182 104.0
HKD1_k127_1409256_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000003767 173.0
HKD1_k127_1409256_1 Protein of unknown function (DUF1304) K08987 - - 0.000000000000000000002517 100.0
HKD1_k127_1409256_2 Protein of unknown function, DUF488 - - - 0.00000000000000000307 85.0
HKD1_k127_1432899_0 Signal transduction histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 443.0
HKD1_k127_1432899_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 347.0
HKD1_k127_1432899_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 290.0
HKD1_k127_1432899_4 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000168 258.0
HKD1_k127_1432899_5 PFAM Protein kinase domain K08309 - - 0.000000000000000000000000000000000000000000000000000002327 203.0
HKD1_k127_1432899_6 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000005944 193.0
HKD1_k127_1432899_7 protein kinase activity - - - 0.00000000000000000000000000000000001249 140.0
HKD1_k127_1432899_8 Putative zinc-finger - - - 0.000000000000000000000000000000002617 140.0
HKD1_k127_1432899_9 Redoxin K02199 - - 0.0000000000000000000000000000001473 136.0
HKD1_k127_1434582_0 Zn_pept - - - 2.778e-205 652.0
HKD1_k127_1434582_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 419.0
HKD1_k127_1434582_2 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000003291 178.0
HKD1_k127_1434582_3 oxidoreductase activity - - - 0.000000000000000000000000000000000000000001873 172.0
HKD1_k127_1434582_4 - - - - 0.0000000000000000000000000000000000000000622 162.0
HKD1_k127_1434582_5 - - - - 0.000000000000000000000000000000006981 134.0
HKD1_k127_1434582_6 Sodium Bile acid symporter family - - - 0.0000000000000000000000000002955 131.0
HKD1_k127_1434582_7 Evidence 4 Homologs of previously reported genes of K21440 - - 0.00000000000000002353 92.0
HKD1_k127_1434582_8 FHA domain - - - 0.000005356 59.0
HKD1_k127_1434582_9 Domain of unknown function (DUF4136) - - - 0.0002275 51.0
HKD1_k127_1448736_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1087.0
HKD1_k127_1448736_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 5.217e-214 675.0
HKD1_k127_1448736_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 497.0
HKD1_k127_1448736_3 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003935 289.0
HKD1_k127_1448736_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000001518 165.0
HKD1_k127_1448736_6 - - - - 0.0000000000000000000000000000000000000001608 157.0
HKD1_k127_1449748_0 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 601.0
HKD1_k127_1449748_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
HKD1_k127_1450125_0 alpha beta - - - 1.291e-201 649.0
HKD1_k127_1450125_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 360.0
HKD1_k127_1450125_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 291.0
HKD1_k127_1450125_3 Protein conserved in bacteria K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000001209 248.0
HKD1_k127_1450125_4 FR47-like protein - - - 0.000000000000000000000000000000002549 145.0
HKD1_k127_1474110_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.0 1011.0
HKD1_k127_1474110_1 amine dehydrogenase activity - - - 4.694e-206 672.0
HKD1_k127_1474110_10 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000006475 113.0
HKD1_k127_1474110_12 Putative zinc-finger - - - 0.000002842 56.0
HKD1_k127_1474110_2 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 338.0
HKD1_k127_1474110_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 324.0
HKD1_k127_1474110_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 299.0
HKD1_k127_1474110_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000006703 210.0
HKD1_k127_1474110_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000686 207.0
HKD1_k127_1474110_7 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000002514 185.0
HKD1_k127_1474110_9 Domain of unknown function (DUF1844) - - - 0.00000000000000000000001892 114.0
HKD1_k127_1487604_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000007354 238.0
HKD1_k127_1487604_1 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001062 212.0
HKD1_k127_1487604_2 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000000001511 187.0
HKD1_k127_1487604_3 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000344 154.0
HKD1_k127_1487604_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000003407 79.0
HKD1_k127_1498016_0 helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 601.0
HKD1_k127_1498016_1 Chorismate mutase K00210,K04092,K04093,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,5.4.99.5 0.000000000000000000000000000000000000000000000000001064 188.0
HKD1_k127_1522885_0 MMPL family K07003 - - 7.708e-198 649.0
HKD1_k127_1522885_1 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 541.0
HKD1_k127_1522885_10 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000001729 150.0
HKD1_k127_1522885_11 FR47-like protein - - - 0.0000000000000000000000000003724 132.0
HKD1_k127_1522885_12 - - - - 0.000000000000000000000000001834 116.0
HKD1_k127_1522885_13 Acyltransferase - - - 0.000000000000000000000003697 113.0
HKD1_k127_1522885_14 Stigma-specific protein, Stig1 - - - 0.00000000000000000000003515 114.0
HKD1_k127_1522885_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 424.0
HKD1_k127_1522885_3 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 318.0
HKD1_k127_1522885_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 308.0
HKD1_k127_1522885_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002903 265.0
HKD1_k127_1522885_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000001728 248.0
HKD1_k127_1522885_7 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000003392 211.0
HKD1_k127_1522885_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000005097 204.0
HKD1_k127_1522885_9 - - - - 0.00000000000000000000000000000000000000000000008242 184.0
HKD1_k127_1525109_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 500.0
HKD1_k127_1525109_1 metallopeptidase activity - - - 0.00000000000000000000000004448 116.0
HKD1_k127_1544686_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 544.0
HKD1_k127_1544686_1 - - - - 0.0000000000000000000000000000000000000000000000000164 190.0
HKD1_k127_1544686_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000002714 106.0
HKD1_k127_1551365_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.6e-263 831.0
HKD1_k127_1551365_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 279.0
HKD1_k127_1551365_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001692 228.0
HKD1_k127_1551365_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002571 170.0
HKD1_k127_1551365_4 Universal stress protein - - - 0.00000000000000000000003306 104.0
HKD1_k127_1551365_5 Cytochrome c - - - 0.00000000000000000000007259 110.0
HKD1_k127_1551365_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000003622 87.0
HKD1_k127_1551365_8 PFAM CBS domain containing protein - - - 0.000002693 57.0
HKD1_k127_1551365_9 Universal stress protein K11932 - - 0.0004502 50.0
HKD1_k127_1554780_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.929e-270 860.0
HKD1_k127_1554780_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
HKD1_k127_1554780_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001311 112.0
HKD1_k127_1554780_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000926 60.0
HKD1_k127_1555245_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.661e-223 734.0
HKD1_k127_1555245_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 517.0
HKD1_k127_1555245_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003486 253.0
HKD1_k127_1555245_3 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001725 261.0
HKD1_k127_1555245_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000002094 97.0
HKD1_k127_156677_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
HKD1_k127_156677_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000001201 174.0
HKD1_k127_156677_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000005693 128.0
HKD1_k127_1577696_0 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 303.0
HKD1_k127_1577696_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000008631 211.0
HKD1_k127_1577696_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000001152 143.0
HKD1_k127_160449_0 GTP cyclohydrolase N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 439.0
HKD1_k127_160449_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000003068 201.0
HKD1_k127_160449_2 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000497 83.0
HKD1_k127_1639204_0 Sigma-54 dependent transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 382.0
HKD1_k127_1639204_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 337.0
HKD1_k127_1639204_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002139 276.0
HKD1_k127_1639204_3 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000002667 259.0
HKD1_k127_1639204_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000006339 206.0
HKD1_k127_1639204_5 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000001942 171.0
HKD1_k127_1639204_6 - - - - 0.00000000000000000000000000000000000000003365 156.0
HKD1_k127_1639204_8 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000008675 130.0
HKD1_k127_1639204_9 Peptidoglycan-binding domain 1 protein - - - 0.00000000001382 75.0
HKD1_k127_1653597_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000009647 166.0
HKD1_k127_1653597_1 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000001675 166.0
HKD1_k127_1653597_2 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000004708 129.0
HKD1_k127_1653597_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000721 102.0
HKD1_k127_1653597_4 Stigma-specific protein, Stig1 - - - 0.0000000000000000000392 102.0
HKD1_k127_1653597_6 response to abiotic stimulus - - - 0.0000000000001503 79.0
HKD1_k127_1653597_7 - - - - 0.00000000000101 76.0
HKD1_k127_1653597_8 - - - - 0.000000000003393 74.0
HKD1_k127_1653597_9 Zinc-dependent metalloprotease - - - 0.000001187 60.0
HKD1_k127_1693584_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 593.0
HKD1_k127_1693584_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 474.0
HKD1_k127_1693584_2 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
HKD1_k127_1693584_3 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.00000000000000000000000000000000000000000000000002785 197.0
HKD1_k127_1693584_4 - - - - 0.0000000000000000000000004931 109.0
HKD1_k127_1693584_5 FAD dependent oxidoreductase - - - 0.000000000000003302 89.0
HKD1_k127_1693584_7 - - - - 0.00000003268 66.0
HKD1_k127_1693584_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000001511 61.0
HKD1_k127_1695549_0 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 540.0
HKD1_k127_1695549_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 496.0
HKD1_k127_1695549_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 495.0
HKD1_k127_170248_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 1.063e-206 658.0
HKD1_k127_170248_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 3.264e-200 643.0
HKD1_k127_170248_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 423.0
HKD1_k127_170248_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 308.0
HKD1_k127_170248_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000003255 218.0
HKD1_k127_170248_6 - - - - 0.000000000000000000000000000000000001256 147.0
HKD1_k127_170248_7 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000003454 106.0
HKD1_k127_170858_0 Proposed nucleic acid binding domain - - - 0.00000000000000000000000000000000000000000000000004698 204.0
HKD1_k127_1711198_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 411.0
HKD1_k127_1711198_1 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 354.0
HKD1_k127_1711198_2 PAS fold - - - 0.0000000000000000000000000000000212 131.0
HKD1_k127_1711198_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000001235 98.0
HKD1_k127_1711198_4 Domain of unknown function (DUF4382) - - - 0.0000000000000005865 87.0
HKD1_k127_1711198_5 protein kinase activity - - - 0.0000000000001183 83.0
HKD1_k127_1711198_7 Putative MetA-pathway of phenol degradation - - - 0.0000001501 64.0
HKD1_k127_1717352_0 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 521.0
HKD1_k127_1717352_1 Domain of unknown function DUF87 - - - 0.0000000003278 67.0
HKD1_k127_1717352_2 radical SAM domain protein - - - 0.00006916 51.0
HKD1_k127_1718135_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 569.0
HKD1_k127_1718135_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 489.0
HKD1_k127_1718135_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 359.0
HKD1_k127_1718135_3 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 321.0
HKD1_k127_1718135_4 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000409 260.0
HKD1_k127_1718135_5 DNA-binding regulatory protein K03088 - - 0.000000000000000000000000000000000000000000000000001009 192.0
HKD1_k127_1718135_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000005872 106.0
HKD1_k127_1718135_7 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000004548 102.0
HKD1_k127_171822_0 IgGFc binding protein - - - 1.988e-223 716.0
HKD1_k127_171822_1 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 436.0
HKD1_k127_171822_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 424.0
HKD1_k127_171822_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000007865 149.0
HKD1_k127_171822_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000003339 103.0
HKD1_k127_171822_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000007517 101.0
HKD1_k127_171822_6 heat shock protein binding - - - 0.00001732 52.0
HKD1_k127_1723061_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 392.0
HKD1_k127_1723061_2 DNA methylase K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000002995 180.0
HKD1_k127_1723061_3 Flavodoxin-like fold K19784 - - 0.00000000000000000000000009173 119.0
HKD1_k127_1743778_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 596.0
HKD1_k127_1743778_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 547.0
HKD1_k127_1743778_2 - - - - 0.000000000000000000000001607 113.0
HKD1_k127_1758172_0 Family membership - - - 2.825e-226 747.0
HKD1_k127_1758172_1 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 424.0
HKD1_k127_1758172_2 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000003082 118.0
HKD1_k127_1758172_4 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000009987 72.0
HKD1_k127_1758172_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000005661 52.0
HKD1_k127_1758727_0 WD40-like Beta Propeller Repeat - - - 4.021e-252 810.0
HKD1_k127_1758727_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.01e-233 747.0
HKD1_k127_1758727_2 heat shock protein binding K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 312.0
HKD1_k127_1758727_3 Formyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003474 271.0
HKD1_k127_1758727_4 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000007072 221.0
HKD1_k127_1758727_5 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000001277 201.0
HKD1_k127_1758727_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000008698 150.0
HKD1_k127_1758727_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000001621 87.0
HKD1_k127_1777506_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 325.0
HKD1_k127_1777506_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005048 246.0
HKD1_k127_1777506_2 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000005808 130.0
HKD1_k127_178594_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
HKD1_k127_178594_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003236 288.0
HKD1_k127_178594_2 HD domain - - - 0.0000000000000000000000000000000000000000000000005247 180.0
HKD1_k127_178594_3 protein kinase activity - - - 0.000000000000005844 85.0
HKD1_k127_178594_4 protein kinase activity K12132 - 2.7.11.1 0.00002251 52.0
HKD1_k127_178594_5 PilZ domain - - - 0.0001958 47.0
HKD1_k127_1788082_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 368.0
HKD1_k127_1788082_1 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 377.0
HKD1_k127_1788082_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009346 246.0
HKD1_k127_1788082_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000006755 152.0
HKD1_k127_1788082_4 Acyltransferase family - - - 0.00000000007148 68.0
HKD1_k127_1788082_5 Glycosyl hydrolase, family 25 - - - 0.000001158 61.0
HKD1_k127_1829980_0 Putative modulator of DNA gyrase K03568 - - 1.56e-242 756.0
HKD1_k127_1829980_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 478.0
HKD1_k127_1829980_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 318.0
HKD1_k127_1829980_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
HKD1_k127_1829980_4 proteolysis - - - 0.0000000000000000000000000000000000000000001256 171.0
HKD1_k127_1829980_5 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000001449 168.0
HKD1_k127_1829980_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000003899 164.0
HKD1_k127_1829980_7 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000001756 109.0
HKD1_k127_1860367_0 - - - - 0.00002437 58.0
HKD1_k127_1879521_0 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 499.0
HKD1_k127_1879521_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 293.0
HKD1_k127_1879521_2 - - - - 0.00000000000000000000000000000000000000000000000000000000428 227.0
HKD1_k127_1879521_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000007427 146.0
HKD1_k127_1879521_4 PIN domain - - - 0.0000000000000000000000000001874 123.0
HKD1_k127_1879521_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000867 70.0
HKD1_k127_1880262_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 387.0
HKD1_k127_1880262_1 depolymerase K05973 - 3.1.1.75 0.00000000167 69.0
HKD1_k127_1909155_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 2.661e-262 830.0
HKD1_k127_1909155_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000006235 179.0
HKD1_k127_1909155_2 - - - - 0.00000000000002258 87.0
HKD1_k127_1910619_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 569.0
HKD1_k127_1910619_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 392.0
HKD1_k127_1910619_2 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 305.0
HKD1_k127_1910619_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000002105 179.0
HKD1_k127_1910619_4 COGs COG2912 conserved - - - 0.0000000000000000000000000000000000000000000005682 177.0
HKD1_k127_1910619_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000001137 162.0
HKD1_k127_1910619_6 - - - - 0.000000000000385 76.0
HKD1_k127_1915776_0 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 545.0
HKD1_k127_1915776_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000003033 166.0
HKD1_k127_1915776_3 isomerase activity - - - 0.0000000000000000001171 100.0
HKD1_k127_1915776_5 Serine threonine protein kinase - - - 0.00000002016 65.0
HKD1_k127_1915776_6 PFAM Rhodanese domain protein K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0001185 49.0
HKD1_k127_1917465_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.0 1036.0
HKD1_k127_1917465_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 342.0
HKD1_k127_1940476_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 457.0
HKD1_k127_1940476_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 438.0
HKD1_k127_1940476_2 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
HKD1_k127_1940476_3 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 353.0
HKD1_k127_1940476_4 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000003799 207.0
HKD1_k127_1940476_5 BON domain - - - 0.0000000000000000000000000000000000000000000003038 177.0
HKD1_k127_1940476_6 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000001195 173.0
HKD1_k127_1940476_7 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000002126 129.0
HKD1_k127_1940476_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000001336 99.0
HKD1_k127_1940476_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000001521 91.0
HKD1_k127_1943143_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 428.0
HKD1_k127_1943143_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 357.0
HKD1_k127_1943143_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 351.0
HKD1_k127_1948679_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000007016 81.0
HKD1_k127_1948679_1 HNH nucleases - - - 0.000000003152 66.0
HKD1_k127_1948679_2 Vitamin K-dependent gamma-carboxylase - - - 0.0000001113 64.0
HKD1_k127_1948679_3 Evidence 5 No homology to any previously reported sequences - - - 0.000002504 56.0
HKD1_k127_1953717_0 Beta-lactamase - - - 2.499e-222 709.0
HKD1_k127_1953717_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 531.0
HKD1_k127_1953717_2 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000001917 181.0
HKD1_k127_195638_0 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD1_k127_195638_1 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000003702 172.0
HKD1_k127_195638_2 - - - - 0.000000000000002201 87.0
HKD1_k127_1963436_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1508.0
HKD1_k127_1963436_1 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000213 261.0
HKD1_k127_1963436_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000006018 200.0
HKD1_k127_1963436_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000001445 199.0
HKD1_k127_1963436_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000000000000000000000000008932 132.0
HKD1_k127_1964225_0 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 311.0
HKD1_k127_1964225_1 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000007003 130.0
HKD1_k127_1964225_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002524 108.0
HKD1_k127_1965416_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 376.0
HKD1_k127_1965416_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
HKD1_k127_1965416_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000003941 153.0
HKD1_k127_197707_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 404.0
HKD1_k127_197707_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 366.0
HKD1_k127_197707_2 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000001266 174.0
HKD1_k127_197707_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000001883 165.0
HKD1_k127_197707_4 ester cyclase - - - 0.000000000000000000000001207 109.0
HKD1_k127_197707_5 Leucine rich repeat containing 40 - GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006897,GO:0006909,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016192,GO:0023052,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0065007,GO:0071944,GO:0098657 - 0.0000000000000001493 91.0
HKD1_k127_197707_6 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) K07273 - - 0.0000008746 61.0
HKD1_k127_1980813_0 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 437.0
HKD1_k127_1980813_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 434.0
HKD1_k127_1980813_2 - - - - 0.00000000000000000000000000000000000000000007803 171.0
HKD1_k127_1980813_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000733 53.0
HKD1_k127_1980875_0 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 421.0
HKD1_k127_1980875_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 367.0
HKD1_k127_1980875_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 309.0
HKD1_k127_1980875_3 R3H domain K06346 - - 0.000000000000000000000000000000000000000000002053 170.0
HKD1_k127_1980875_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000002714 139.0
HKD1_k127_1980875_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000004866 105.0
HKD1_k127_1980875_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000276 86.0
HKD1_k127_1992318_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 610.0
HKD1_k127_1992318_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 465.0
HKD1_k127_1992318_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 358.0
HKD1_k127_1992318_3 PFAM ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000006079 130.0
HKD1_k127_1992318_6 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000001688 74.0
HKD1_k127_1992318_7 DNA-binding transcription factor activity - - - 0.00000005433 63.0
HKD1_k127_1992318_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0009326 51.0
HKD1_k127_2005459_0 adventurous gliding protein T - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 397.0
HKD1_k127_2005459_1 Protein of unknown function (DUF1156) - - - 0.0000000000000000000004056 100.0
HKD1_k127_2005459_2 23S rRNA-intervening sequence protein - - - 0.00000000003605 67.0
HKD1_k127_201864_0 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 453.0
HKD1_k127_201864_1 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002267 291.0
HKD1_k127_201864_2 - - - - 0.0000000000000000000000000000000000000000000000000000003261 203.0
HKD1_k127_201864_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000001766 194.0
HKD1_k127_201864_4 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000005651 165.0
HKD1_k127_201864_5 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000001116 123.0
HKD1_k127_201864_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000001349 121.0
HKD1_k127_201864_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000155 57.0
HKD1_k127_201864_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00001327 53.0
HKD1_k127_2023772_0 von Willebrand factor (vWF) type A domain - - - 1.706e-246 771.0
HKD1_k127_2023772_1 PFAM amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 620.0
HKD1_k127_2023772_10 - - - - 0.000000000000000000000000001208 113.0
HKD1_k127_2023772_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000004792 118.0
HKD1_k127_2023772_13 - - - - 0.00000005851 66.0
HKD1_k127_2023772_2 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 552.0
HKD1_k127_2023772_3 phosphorelay signal transduction system K10941,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 456.0
HKD1_k127_2023772_4 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 275.0
HKD1_k127_2023772_5 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000001053 254.0
HKD1_k127_2023772_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000209 235.0
HKD1_k127_2023772_7 - - - - 0.000000000000000000000000000000000000000009552 156.0
HKD1_k127_2023772_8 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000001208 158.0
HKD1_k127_2032501_0 protein containing a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.915e-199 646.0
HKD1_k127_2032501_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003546 272.0
HKD1_k127_2033096_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 456.0
HKD1_k127_2033096_1 Putative zinc-finger - - - 0.000000000000000000000000004346 115.0
HKD1_k127_2033096_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000004558 110.0
HKD1_k127_2033096_3 Belongs to the ompA family K20276 - - 0.000000000000000000000002731 102.0
HKD1_k127_2033096_4 amine dehydrogenase activity - - - 0.0001875 53.0
HKD1_k127_2047533_0 von Willebrand factor type A domain - - - 0.0 1133.0
HKD1_k127_2047533_1 Aerotolerance regulator N-terminal - - - 3.895e-227 721.0
HKD1_k127_2047533_10 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002064 276.0
HKD1_k127_2047533_11 ATP-NAD kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002398 259.0
HKD1_k127_2047533_12 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000002716 172.0
HKD1_k127_2047533_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000008317 141.0
HKD1_k127_2047533_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000001254 129.0
HKD1_k127_2047533_15 Family membership K12132 - 2.7.11.1 0.000000000000000000000001536 113.0
HKD1_k127_2047533_16 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000001093 113.0
HKD1_k127_2047533_17 23S rRNA-intervening sequence protein - - - 0.00000000000000000000001346 109.0
HKD1_k127_2047533_19 serine threonine protein kinase K15923 - 3.2.1.51 0.0007475 51.0
HKD1_k127_2047533_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 490.0
HKD1_k127_2047533_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 480.0
HKD1_k127_2047533_4 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 465.0
HKD1_k127_2047533_5 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 485.0
HKD1_k127_2047533_6 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 418.0
HKD1_k127_2047533_7 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 363.0
HKD1_k127_2047533_8 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 340.0
HKD1_k127_2047533_9 Forkhead associated domain K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 321.0
HKD1_k127_2048309_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 372.0
HKD1_k127_2048309_1 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 354.0
HKD1_k127_2048309_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001822 274.0
HKD1_k127_204972_0 Class II Aldolase and Adducin N-terminal domain - - - 8.893e-264 837.0
HKD1_k127_204972_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 330.0
HKD1_k127_204972_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
HKD1_k127_204972_3 - - - - 0.0000000000000000000000000000000000000005034 164.0
HKD1_k127_204972_4 Ricin-type beta-trefoil lectin domain-like - - - 0.00000000000000000002961 104.0
HKD1_k127_2050208_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
HKD1_k127_2050208_1 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000006021 111.0
HKD1_k127_2050208_2 - - - - 0.0000000000001978 80.0
HKD1_k127_2054311_0 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
HKD1_k127_2054311_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000003367 270.0
HKD1_k127_2054311_2 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005462 292.0
HKD1_k127_2054311_3 of the major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000755 246.0
HKD1_k127_2054311_4 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000001313 222.0
HKD1_k127_2054311_5 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000002249 202.0
HKD1_k127_2054311_6 guanyl-nucleotide exchange factor activity K02034 - - 0.0000000000000000000000001624 119.0
HKD1_k127_2054311_7 - - - - 0.000005234 54.0
HKD1_k127_2054311_8 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0001086 45.0
HKD1_k127_2061776_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 386.0
HKD1_k127_2061776_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 358.0
HKD1_k127_2061776_2 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 311.0
HKD1_k127_2061776_3 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000000000001586 192.0
HKD1_k127_2061776_4 AAA ATPase domain - - - 0.00000000000000000000000000000000000000003498 172.0
HKD1_k127_2061776_5 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000004272 161.0
HKD1_k127_2061776_6 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000002578 141.0
HKD1_k127_2061776_7 Beta-L-arabinofuranosidase, GH127 - - - 0.0007599 52.0
HKD1_k127_2063034_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.082e-243 762.0
HKD1_k127_2063034_1 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 561.0
HKD1_k127_2063034_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 397.0
HKD1_k127_2063034_3 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HKD1_k127_2063034_4 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000002404 235.0
HKD1_k127_2063034_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000456 240.0
HKD1_k127_2063034_6 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000005027 176.0
HKD1_k127_2063034_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000003496 122.0
HKD1_k127_2063034_8 Domain of unknown function (DUF4253) - - - 0.00000003465 61.0
HKD1_k127_2071272_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 447.0
HKD1_k127_2071272_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001046 292.0
HKD1_k127_2071272_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001335 254.0
HKD1_k127_2071272_3 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000008179 184.0
HKD1_k127_2071272_4 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000005004 171.0
HKD1_k127_2071272_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000006802 156.0
HKD1_k127_2071272_7 Protein of unknown function (DUF3298) - - - 0.00000009175 65.0
HKD1_k127_2071272_8 DNA-sulfur modification-associated - - - 0.000003017 59.0
HKD1_k127_2082386_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 269.0
HKD1_k127_2082386_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002814 262.0
HKD1_k127_2082386_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000144 175.0
HKD1_k127_2082386_3 cell envelope organization K05807,K08309 - - 0.0000003754 61.0
HKD1_k127_2092578_0 GAF domain - - - 5.064e-203 649.0
HKD1_k127_2092578_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 378.0
HKD1_k127_2092578_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 319.0
HKD1_k127_2092578_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003272 268.0
HKD1_k127_2092578_4 Flagellar Motor Protein K11892 - - 0.0000000000000000000000000000000000000001493 154.0
HKD1_k127_2092578_5 translation initiation factor activity K01972,K02342,K03646 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000001161 128.0
HKD1_k127_2092578_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000001263 98.0
HKD1_k127_2092578_7 pyrroloquinoline quinone binding - - - 0.0000000000000000008793 91.0
HKD1_k127_2092578_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000008862 59.0
HKD1_k127_2092578_9 - - - - 0.0000001845 61.0
HKD1_k127_2119189_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 1.896e-237 745.0
HKD1_k127_2119189_1 response regulator K02481,K07713 - - 2.353e-196 649.0
HKD1_k127_2119189_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 598.0
HKD1_k127_2119189_3 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 520.0
HKD1_k127_2119189_4 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000001591 171.0
HKD1_k127_2119189_5 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000003231 137.0
HKD1_k127_2119189_6 Universal stress protein - - - 0.000000000000000000002373 102.0
HKD1_k127_2120085_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 548.0
HKD1_k127_2120085_1 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 346.0
HKD1_k127_2120085_2 - - - - 0.00000000001736 77.0
HKD1_k127_2124681_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 612.0
HKD1_k127_2136757_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000113 282.0
HKD1_k127_2152156_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 542.0
HKD1_k127_2152156_1 iron ion transport K07224 - - 0.0000000000000000000000000000000000000000000000000000008021 204.0
HKD1_k127_2152156_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000001367 200.0
HKD1_k127_2152156_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000008665 91.0
HKD1_k127_2152156_4 Domain of unknown function (DUF4132) - - - 0.000000000001117 81.0
HKD1_k127_215223_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 541.0
HKD1_k127_215223_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000007377 224.0
HKD1_k127_215223_2 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000002719 153.0
HKD1_k127_2153703_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 230.0
HKD1_k127_2153703_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000007772 117.0
HKD1_k127_2154204_0 Family membership - - - 5.075e-249 813.0
HKD1_k127_2154204_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 573.0
HKD1_k127_2154204_2 glyoxalase III activity - - - 0.0000000000000000000000000000001051 143.0
HKD1_k127_2154204_3 glyoxalase III activity - - - 0.000541 51.0
HKD1_k127_2179633_0 PrkA AAA domain K07180 - - 0.0 1148.0
HKD1_k127_2179633_1 Glycoside hydrolase family 44 - - - 7.23e-208 668.0
HKD1_k127_2179633_10 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000007279 155.0
HKD1_k127_2179633_13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000001176 60.0
HKD1_k127_2179633_14 COG1520 FOG WD40-like repeat - - - 0.000003798 58.0
HKD1_k127_2179633_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 439.0
HKD1_k127_2179633_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004717 281.0
HKD1_k127_2179633_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000005445 216.0
HKD1_k127_2179633_5 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000152 213.0
HKD1_k127_2179633_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000006018 205.0
HKD1_k127_2179633_7 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000005029 211.0
HKD1_k127_2179633_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000135 181.0
HKD1_k127_2179633_9 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000002049 177.0
HKD1_k127_2196813_0 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 360.0
HKD1_k127_2196813_1 BtpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003176 266.0
HKD1_k127_2196813_2 Regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000000000000000000001413 231.0
HKD1_k127_2196813_3 catalase activity - - - 0.0000000000000000000000000000000000000000000006907 178.0
HKD1_k127_2196813_4 peptidyl-tyrosine sulfation - - - 0.000000000000614 72.0
HKD1_k127_2199841_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 2.39e-237 751.0
HKD1_k127_2199841_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 487.0
HKD1_k127_2199841_10 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000008151 86.0
HKD1_k127_2199841_11 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.00000002231 67.0
HKD1_k127_2199841_12 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000003519 59.0
HKD1_k127_2199841_2 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 490.0
HKD1_k127_2199841_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 293.0
HKD1_k127_2199841_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000002643 188.0
HKD1_k127_2199841_5 B domain of TMEM189, localisation domain K20656 - - 0.0000000000000000000000000000000000000001807 156.0
HKD1_k127_2199841_8 - - - - 0.00000000000000000000001035 109.0
HKD1_k127_2199841_9 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000009169 107.0
HKD1_k127_2206745_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 586.0
HKD1_k127_2206745_1 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000003405 250.0
HKD1_k127_2206745_2 serine threonine protein kinase - - - 0.0000001855 57.0
HKD1_k127_2206745_3 PFAM regulatory protein LuxR - - - 0.0000006359 56.0
HKD1_k127_2206745_4 - - - - 0.00001436 49.0
HKD1_k127_2206745_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0004395 45.0
HKD1_k127_2208003_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.772e-200 642.0
HKD1_k127_2208003_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 368.0
HKD1_k127_2208003_2 Phage shock protein A K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000001225 201.0
HKD1_k127_2208003_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.000000000000000000000000000000000000000000000002905 186.0
HKD1_k127_2208003_6 oxidoreductase activity K07114 - - 0.000000000001821 79.0
HKD1_k127_2208003_7 - - - - 0.000000001971 67.0
HKD1_k127_2208003_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000001174 59.0
HKD1_k127_2208003_9 Phage shock protein A K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.00006179 45.0
HKD1_k127_2210918_0 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 505.0
HKD1_k127_2210918_1 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 482.0
HKD1_k127_2210918_10 Rieske fe-s protein K02636 - 1.10.9.1 0.0000000000008578 75.0
HKD1_k127_2210918_11 Domain of unknown function (DUF4412) - - - 0.000000555 61.0
HKD1_k127_2210918_2 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 404.0
HKD1_k127_2210918_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 299.0
HKD1_k127_2210918_4 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 301.0
HKD1_k127_2210918_5 transcriptional regulator - - - 0.00000000000000000000000000000000000001028 152.0
HKD1_k127_2210918_6 modulation by symbiont of host adenylate cyclase-mediated signal transduction K03775 - 5.2.1.8 0.00000000000000000000000005457 113.0
HKD1_k127_2210918_7 RNA polymerase sigma factor K03088 - - 0.000000000000000000004544 95.0
HKD1_k127_2210918_8 COG1073 hydrolases of the alpha beta superfamily - - - 0.0000000000000000002429 104.0
HKD1_k127_2250454_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 5.061e-220 690.0
HKD1_k127_2250454_1 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 391.0
HKD1_k127_2250454_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001999 261.0
HKD1_k127_2250454_3 - - - - 0.000000000000000000000000000000000000000000001077 180.0
HKD1_k127_2250454_4 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000728 119.0
HKD1_k127_2250454_5 - - - - 0.0000000000000000002944 97.0
HKD1_k127_2253700_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 436.0
HKD1_k127_2253700_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 316.0
HKD1_k127_2253700_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
HKD1_k127_2253700_3 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000034 173.0
HKD1_k127_2253700_5 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.00000000329 66.0
HKD1_k127_2257024_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 393.0
HKD1_k127_2270813_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.727e-205 648.0
HKD1_k127_2270813_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 385.0
HKD1_k127_2270813_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 284.0
HKD1_k127_2270813_3 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
HKD1_k127_2270813_4 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
HKD1_k127_2270813_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001602 95.0
HKD1_k127_2270813_6 peptidyl-tyrosine sulfation - - - 0.0000005729 58.0
HKD1_k127_227644_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004188 240.0
HKD1_k127_227644_1 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000002021 186.0
HKD1_k127_2290467_0 acetyltransferase - - - 4.7e-201 631.0
HKD1_k127_2290467_1 protein kinase activity - - - 0.000000000000000002313 96.0
HKD1_k127_2294701_0 Glycosyl hydrolase family 92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 598.0
HKD1_k127_2294701_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000009917 216.0
HKD1_k127_2294701_2 Bifunctional nuclease K08999 - - 0.000000000000000003769 92.0
HKD1_k127_2296792_0 VWA domain containing CoxE-like protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 468.0
HKD1_k127_2296792_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 292.0
HKD1_k127_2296792_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000004937 113.0
HKD1_k127_2298072_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
HKD1_k127_2298072_1 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
HKD1_k127_2298072_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000195 238.0
HKD1_k127_2298072_3 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000002271 182.0
HKD1_k127_2298072_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000001009 164.0
HKD1_k127_2298072_5 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000003285 148.0
HKD1_k127_2298072_6 IgGFc binding protein - - - 0.000000000000000000000000000000001431 130.0
HKD1_k127_2298072_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03892 - - 0.000000000000000000000101 107.0
HKD1_k127_2298072_8 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000001386 108.0
HKD1_k127_2298072_9 Protein of unknown function (DUF2892) - - - 0.00000000000000000002849 91.0
HKD1_k127_2310569_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1339.0
HKD1_k127_2310569_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
HKD1_k127_2310569_10 - - - - 0.00000001115 66.0
HKD1_k127_2310569_11 - - - - 0.00000007107 65.0
HKD1_k127_2310569_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 449.0
HKD1_k127_2310569_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 359.0
HKD1_k127_2310569_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001212 180.0
HKD1_k127_2310569_5 polysaccharide export K01991 - - 0.00000000000000000000000000000000000002131 166.0
HKD1_k127_2310569_8 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000007169 134.0
HKD1_k127_2318588_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HKD1_k127_2318588_1 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 330.0
HKD1_k127_2318588_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000638 184.0
HKD1_k127_2318588_4 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000002698 105.0
HKD1_k127_2332641_0 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 508.0
HKD1_k127_2332641_1 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 323.0
HKD1_k127_2341146_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 383.0
HKD1_k127_2341146_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000001596 235.0
HKD1_k127_2341146_2 - - - - 0.000000000000000000001487 103.0
HKD1_k127_2341146_3 Protein of unknown function (DUF3175) - - - 0.000000000000000004181 87.0
HKD1_k127_2341146_4 Thioredoxin-like - - - 0.00007244 48.0
HKD1_k127_2356792_0 long-chain fatty acid transport protein K06076 - - 0.0000000000002769 83.0
HKD1_k127_2356792_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000004539 81.0
HKD1_k127_2356792_4 long-chain fatty acid transport protein K06076 - - 0.0008962 48.0
HKD1_k127_236470_0 PFAM Glycosyl transferase, group 1 - - - 2.364e-215 684.0
HKD1_k127_236470_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 467.0
HKD1_k127_236470_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 308.0
HKD1_k127_236470_3 Belongs to the GbsR family - - - 0.0000004377 55.0
HKD1_k127_236470_4 Parallel beta-helix repeat-containing protein - - - 0.0000005893 62.0
HKD1_k127_23762_0 transporter - - - 1.822e-201 640.0
HKD1_k127_23762_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 436.0
HKD1_k127_23762_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000009693 248.0
HKD1_k127_23762_3 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000002335 214.0
HKD1_k127_23762_4 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000007604 213.0
HKD1_k127_2376779_0 Methylmalonyl-CoA mutase - - - 1e-323 1021.0
HKD1_k127_2376779_1 ArgK protein K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000000000000000000000000001207 158.0
HKD1_k127_2379776_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 324.0
HKD1_k127_2379776_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 282.0
HKD1_k127_2379776_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000002271 171.0
HKD1_k127_2379776_3 - - - - 0.0000000000000004933 91.0
HKD1_k127_2387576_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 512.0
HKD1_k127_2387576_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 484.0
HKD1_k127_2387576_10 cell adhesion - - - 0.000000000000000000000001134 111.0
HKD1_k127_2387576_12 PD-(D/E)XK nuclease superfamily - - - 0.000001419 58.0
HKD1_k127_2387576_2 PFAM sigma-54 factor interaction domain-containing protein K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 368.0
HKD1_k127_2387576_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 359.0
HKD1_k127_2387576_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 332.0
HKD1_k127_2387576_5 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 321.0
HKD1_k127_2387576_6 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 300.0
HKD1_k127_2387576_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000001779 149.0
HKD1_k127_2387576_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000002321 134.0
HKD1_k127_2387576_9 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000009232 113.0
HKD1_k127_2391558_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000002504 198.0
HKD1_k127_2391558_1 PEGA domain - - - 0.0000000000000000000000001025 124.0
HKD1_k127_2391599_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 374.0
HKD1_k127_2391599_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007884 259.0
HKD1_k127_2391599_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000001328 188.0
HKD1_k127_2391599_3 Alpha beta hydrolase K03929 - - 0.0000000000000000000000000000005157 127.0
HKD1_k127_2391599_4 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000001266 82.0
HKD1_k127_2391599_5 response regulator - - - 0.00007291 53.0
HKD1_k127_2391599_6 COG2771 DNA-binding HTH domain-containing proteins - - - 0.0002306 49.0
HKD1_k127_2400404_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 309.0
HKD1_k127_2400404_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000002181 177.0
HKD1_k127_2400404_3 cell envelope organization K05807,K08309 - - 0.0000000000001008 83.0
HKD1_k127_2400404_4 amine dehydrogenase activity - - - 0.0000007363 61.0
HKD1_k127_2406384_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 449.0
HKD1_k127_2406384_1 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 305.0
HKD1_k127_2406384_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000001567 163.0
HKD1_k127_2406384_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000241 83.0
HKD1_k127_2410776_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 368.0
HKD1_k127_2410776_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000003314 225.0
HKD1_k127_2410776_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002308 231.0
HKD1_k127_2410776_4 Oxidoreductase NAD-binding domain K20784 - - 0.00000000000323 76.0
HKD1_k127_2410776_5 zinc ion binding - - - 0.000000000005896 76.0
HKD1_k127_2415149_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1087.0
HKD1_k127_2415149_1 6-phosphogluconolactonase activity - - - 0.000000000000000007596 94.0
HKD1_k127_2415149_2 Transcriptional regulator, AraC family K07506 - - 0.00000000000000001999 93.0
HKD1_k127_2415149_3 aspartic-type endopeptidase activity K06399 - 3.4.21.116 0.0000001562 63.0
HKD1_k127_2427169_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
HKD1_k127_2427169_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000002652 82.0
HKD1_k127_2427169_2 AAA domain (Cdc48 subfamily) - - - 0.000003985 59.0
HKD1_k127_2430554_0 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 364.0
HKD1_k127_2430554_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008957 255.0
HKD1_k127_2430554_2 - - - - 0.000000001554 71.0
HKD1_k127_2437789_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002867 280.0
HKD1_k127_2437789_1 alpha beta - - - 0.00000001253 68.0
HKD1_k127_2445125_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 429.0
HKD1_k127_2445125_1 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 296.0
HKD1_k127_2445125_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
HKD1_k127_2445125_3 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - 0.00000000000000000000000000000000000001839 151.0
HKD1_k127_2445125_4 domain, Protein - - - 0.0000000000000000000000000000000815 135.0
HKD1_k127_2445125_5 - - - - 0.0000000000000000000000000000004699 140.0
HKD1_k127_2445125_6 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000006856 132.0
HKD1_k127_2445125_8 - - - - 0.0000000000000203 85.0
HKD1_k127_2445125_9 domain, Protein - - - 0.00000000000007812 81.0
HKD1_k127_244608_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 453.0
HKD1_k127_244608_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 417.0
HKD1_k127_244608_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 391.0
HKD1_k127_244608_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
HKD1_k127_244608_4 - - - - 0.000000000000000000000000000000006154 129.0
HKD1_k127_244608_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000005667 91.0
HKD1_k127_244608_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.0000000000004209 82.0
HKD1_k127_244608_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000759 73.0
HKD1_k127_244608_8 - - - - 0.000000000926 63.0
HKD1_k127_244700_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 451.0
HKD1_k127_244700_1 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
HKD1_k127_244700_2 phosphorelay signal transduction system K10941,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000001174 239.0
HKD1_k127_244700_3 Tetratricopeptide repeat - - - 0.00000000000000000000000001826 120.0
HKD1_k127_244700_4 - - - - 0.0000000000000000011 99.0
HKD1_k127_244700_5 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.000000000003075 78.0
HKD1_k127_246592_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000107 251.0
HKD1_k127_246592_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001205 253.0
HKD1_k127_246592_2 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000001404 181.0
HKD1_k127_246592_3 - - - - 0.00000000000000000000000000000000000000006504 158.0
HKD1_k127_2480601_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 619.0
HKD1_k127_2480601_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000000002226 197.0
HKD1_k127_2480601_2 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000005357 136.0
HKD1_k127_2481186_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 334.0
HKD1_k127_2481186_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000003287 156.0
HKD1_k127_2481186_2 Transcriptional regulator - - - 0.0000000000000000003859 97.0
HKD1_k127_2481186_3 Domain of unknown function (DUF4352) - - - 0.00004962 53.0
HKD1_k127_2482851_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 388.0
HKD1_k127_2482851_1 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000791 244.0
HKD1_k127_2482851_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000007931 199.0
HKD1_k127_2482851_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000451 67.0
HKD1_k127_2487503_0 Transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 368.0
HKD1_k127_2487503_1 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 359.0
HKD1_k127_2487503_10 Right handed beta helix region - - - 0.0003459 54.0
HKD1_k127_2487503_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004741 256.0
HKD1_k127_2487503_4 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000002565 231.0
HKD1_k127_2487503_5 manually curated - - - 0.000000000000000000000000000000000000000000000000009483 189.0
HKD1_k127_2487503_6 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000004 147.0
HKD1_k127_2487503_7 negative regulation of translational initiation - - - 0.0000000000000000006832 96.0
HKD1_k127_2487503_8 - - - - 0.000000000001011 74.0
HKD1_k127_2487503_9 - - - - 0.0000000143 64.0
HKD1_k127_248788_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000002178 203.0
HKD1_k127_248788_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000553 124.0
HKD1_k127_248788_2 NUDIX domain - - - 0.00000000000000000000005974 103.0
HKD1_k127_248788_3 Flagellar basal body rod K02396 - - 0.00000006309 65.0
HKD1_k127_248788_4 - - - - 0.000001187 60.0
HKD1_k127_2488794_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 436.0
HKD1_k127_2488794_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 381.0
HKD1_k127_2488794_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 337.0
HKD1_k127_2488794_3 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000001044 213.0
HKD1_k127_2488794_4 von Willebrand factor (vWF) type A domain K07114 - - 0.00000003448 65.0
HKD1_k127_2513212_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 2.367e-211 660.0
HKD1_k127_2513212_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002173 249.0
HKD1_k127_2513212_2 - - - - 0.000000000000000000000000000000000000000000000000000000001704 211.0
HKD1_k127_2544897_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009825 286.0
HKD1_k127_2544897_1 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001506 287.0
HKD1_k127_2544897_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002838 240.0
HKD1_k127_2544897_3 PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000003294 214.0
HKD1_k127_2544897_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000001969 197.0
HKD1_k127_2544897_5 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000003159 154.0
HKD1_k127_2545604_0 AcrB/AcrD/AcrF family - - - 7.1e-315 995.0
HKD1_k127_2545604_1 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 304.0
HKD1_k127_2545604_2 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 231.0
HKD1_k127_2545604_3 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000005591 160.0
HKD1_k127_2545604_4 - - - - 0.0000000000000000000000000000000000000009216 153.0
HKD1_k127_2545604_5 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000007722 155.0
HKD1_k127_2545604_6 Outer membrane efflux protein - - - 0.00000000000000000000000001409 124.0
HKD1_k127_2554843_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 455.0
HKD1_k127_2555712_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 370.0
HKD1_k127_2555712_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000244 188.0
HKD1_k127_2555712_2 - - - - 0.000000000000000000000000000000004043 143.0
HKD1_k127_2557630_1 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 343.0
HKD1_k127_2557630_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 319.0
HKD1_k127_2557630_3 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000007527 216.0
HKD1_k127_2557630_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000003365 206.0
HKD1_k127_2557630_5 protein transport across the cell outer membrane - - - 0.00000000000000000002708 96.0
HKD1_k127_2557630_6 cell envelope organization K05807,K08309 - - 0.000000000000000002396 96.0
HKD1_k127_2563762_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 433.0
HKD1_k127_2563762_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 307.0
HKD1_k127_2563762_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003453 282.0
HKD1_k127_2563762_3 - - - - 0.0000000000000000000000000000000000000000000003034 181.0
HKD1_k127_2563762_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000002571 153.0
HKD1_k127_2563762_5 serine-type endopeptidase activity - - - 0.00000001074 67.0
HKD1_k127_2565744_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1326.0
HKD1_k127_2565744_1 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 384.0
HKD1_k127_2565744_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
HKD1_k127_2565744_3 - - - - 0.00000000000000000000000008876 126.0
HKD1_k127_2565744_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.0000001422 54.0
HKD1_k127_2565744_5 SlyX K03745 - - 0.0001541 48.0
HKD1_k127_2567411_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000121 154.0
HKD1_k127_2567411_1 glyoxalase III activity - - - 0.00000000000009785 76.0
HKD1_k127_2567411_2 Belongs to the peptidase S1B family - - - 0.000000003554 67.0
HKD1_k127_2569350_0 Sarcosine oxidase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 595.0
HKD1_k127_2569350_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006457 296.0
HKD1_k127_2569350_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000001812 214.0
HKD1_k127_2569350_3 PFAM PEGA domain - - - 0.00003207 54.0
HKD1_k127_2571093_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 607.0
HKD1_k127_2571093_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 489.0
HKD1_k127_2571093_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000000000000000002306 104.0
HKD1_k127_2571093_6 Alpha/beta hydrolase family - - - 0.000000003758 65.0
HKD1_k127_2578734_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - - 3.7e-322 1011.0
HKD1_k127_2578734_1 WD domain- G-beta repeat PBS lyase HEAT-like K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 611.0
HKD1_k127_2578734_2 Proposed nucleic acid binding domain - - - 0.000000000000000000717 95.0
HKD1_k127_2604944_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000001174 249.0
HKD1_k127_2604944_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000821 188.0
HKD1_k127_2604944_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000116 154.0
HKD1_k127_2604944_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000007444 100.0
HKD1_k127_2606119_0 response regulator K07713 - - 2.264e-215 676.0
HKD1_k127_2606119_1 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001974 282.0
HKD1_k127_2606119_2 cheY-homologous receiver domain - - - 0.0000000000000000000000005046 109.0
HKD1_k127_2613717_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 569.0
HKD1_k127_2613717_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005307 274.0
HKD1_k127_2613717_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003142 243.0
HKD1_k127_2613717_3 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000000000000000000000000000000004846 217.0
HKD1_k127_2613717_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000001347 186.0
HKD1_k127_2613717_5 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000001221 176.0
HKD1_k127_2613717_7 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000009602 101.0
HKD1_k127_2613717_8 response regulator - - - 0.000000002324 71.0
HKD1_k127_2616467_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 473.0
HKD1_k127_2616467_1 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000004701 254.0
HKD1_k127_2616467_10 KH domain K06960 - - 0.0000000000000000000003247 103.0
HKD1_k127_2616467_11 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002347 91.0
HKD1_k127_2616467_13 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000000001141 82.0
HKD1_k127_2616467_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000002322 231.0
HKD1_k127_2616467_3 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000771 209.0
HKD1_k127_2616467_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000004136 177.0
HKD1_k127_2616467_5 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000008205 166.0
HKD1_k127_2616467_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000002568 146.0
HKD1_k127_2616467_7 - - - - 0.0000000000000000000000000000000006178 142.0
HKD1_k127_2616467_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000002441 116.0
HKD1_k127_2624185_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 491.0
HKD1_k127_2624185_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 400.0
HKD1_k127_2624185_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 363.0
HKD1_k127_2624185_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 314.0
HKD1_k127_2624185_4 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 303.0
HKD1_k127_2624185_5 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
HKD1_k127_2624185_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000001134 194.0
HKD1_k127_2624185_7 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000006671 142.0
HKD1_k127_2624185_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000007445 66.0
HKD1_k127_2631497_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000001046 172.0
HKD1_k127_2631497_1 electron transfer activity - - - 0.00000000001167 78.0
HKD1_k127_2637337_0 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 520.0
HKD1_k127_2637337_1 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 493.0
HKD1_k127_2637337_10 amine dehydrogenase activity - - - 0.000000000000000000008678 102.0
HKD1_k127_2637337_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000007449 95.0
HKD1_k127_2637337_12 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000001668 78.0
HKD1_k127_2637337_13 Negative regulator of - - - 0.00000003882 64.0
HKD1_k127_2637337_15 Outer membrane efflux protein K15725 - - 0.000006024 59.0
HKD1_k127_2637337_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 469.0
HKD1_k127_2637337_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 450.0
HKD1_k127_2637337_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 445.0
HKD1_k127_2637337_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 334.0
HKD1_k127_2637337_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000001925 193.0
HKD1_k127_2637337_8 - - - - 0.00000000000000000000000000000000000000000008397 177.0
HKD1_k127_2640541_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 572.0
HKD1_k127_2640541_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 463.0
HKD1_k127_2640541_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000009644 218.0
HKD1_k127_2640541_4 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000201 171.0
HKD1_k127_2640541_5 Mechanosensitive ion channel K05802,K22051 - - 0.00000000000000000000000000000000000000009683 162.0
HKD1_k127_2640541_6 Protein of unknown function (DUF533) K11962 - - 0.00002879 53.0
HKD1_k127_2665115_0 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 428.0
HKD1_k127_2665115_1 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 324.0
HKD1_k127_2665115_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000003058 89.0
HKD1_k127_2671532_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 608.0
HKD1_k127_2671532_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 322.0
HKD1_k127_2671532_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000001044 74.0
HKD1_k127_2691652_0 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 395.0
HKD1_k127_2692363_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 406.0
HKD1_k127_2692363_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002235 241.0
HKD1_k127_269621_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 587.0
HKD1_k127_269621_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 557.0
HKD1_k127_269621_2 - K01822 - 5.3.3.1 0.0000000000000001097 85.0
HKD1_k127_269621_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000697 66.0
HKD1_k127_2702927_0 Carboxyl transferase domain - - - 1.456e-277 859.0
HKD1_k127_2702927_1 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001413 284.0
HKD1_k127_2702927_2 Pfam:Kce - - - 0.000000000000000000000000000000000000000000000000008341 182.0
HKD1_k127_2712088_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1798.0
HKD1_k127_2712088_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000001109 240.0
HKD1_k127_2712088_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000005104 222.0
HKD1_k127_2712088_3 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000009018 179.0
HKD1_k127_2712088_4 GAF domain - - - 0.0000000000000000000000000000000000181 135.0
HKD1_k127_2712088_5 Thioesterase superfamily - - - 0.00000000000000000000000000000009122 126.0
HKD1_k127_2712088_6 Chemotaxis protein CheR K00575 - 2.1.1.80 0.0000000000000000005492 104.0
HKD1_k127_2712749_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 2.611e-206 662.0
HKD1_k127_2712749_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 550.0
HKD1_k127_2712749_10 Protease prsW family - - - 0.00000000000000000000000000000000002084 152.0
HKD1_k127_2712749_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000232 122.0
HKD1_k127_2712749_12 cellulose binding - - - 0.0000000000000000000000000001868 128.0
HKD1_k127_2712749_13 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000001419 121.0
HKD1_k127_2712749_14 PFAM Response regulator receiver domain - - - 0.0000000000145 69.0
HKD1_k127_2712749_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 309.0
HKD1_k127_2712749_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 313.0
HKD1_k127_2712749_4 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006933 274.0
HKD1_k127_2712749_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002069 275.0
HKD1_k127_2712749_6 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000004878 206.0
HKD1_k127_2712749_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000008838 169.0
HKD1_k127_2712749_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000005608 150.0
HKD1_k127_2712749_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000007911 149.0
HKD1_k127_2720403_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 428.0
HKD1_k127_2720403_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002314 263.0
HKD1_k127_2720403_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000651 178.0
HKD1_k127_2720403_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000664 88.0
HKD1_k127_2720403_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000002406 75.0
HKD1_k127_2720403_5 YceI-like domain - - - 0.000000003277 68.0
HKD1_k127_2720403_6 Peptidoglycan-binding domain 1 protein - - - 0.00000007671 64.0
HKD1_k127_2723526_0 DNA ligase OB-like domain K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 504.0
HKD1_k127_2723526_1 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 487.0
HKD1_k127_2723526_2 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 448.0
HKD1_k127_2723526_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 349.0
HKD1_k127_2723526_4 S-adenosylhomocysteine deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000941 276.0
HKD1_k127_2723526_5 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.00000000000000000000000000000000000000000000000000009198 200.0
HKD1_k127_2723526_6 AAA domain - - - 0.000000000000000000000000003357 126.0
HKD1_k127_2723526_7 WGR domain protein - - - 0.00000000000000000000000001158 116.0
HKD1_k127_2723526_8 SnoaL-like domain - - - 0.000000000000006341 83.0
HKD1_k127_2723526_9 - - - - 0.00008779 49.0
HKD1_k127_2724062_0 Putative modulator of DNA gyrase K03568 - - 9.509e-228 715.0
HKD1_k127_2724062_1 NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 623.0
HKD1_k127_2724062_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 514.0
HKD1_k127_2724062_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 463.0
HKD1_k127_2724062_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 408.0
HKD1_k127_2724062_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 340.0
HKD1_k127_2724062_6 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000746 304.0
HKD1_k127_2724062_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004532 239.0
HKD1_k127_2724062_8 Domain of unknown function (DUF4184) - - - 0.00000000000000005396 90.0
HKD1_k127_2724062_9 Domain of unknown function (DUF4173) - - - 0.00000000001101 76.0
HKD1_k127_27393_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 523.0
HKD1_k127_27393_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 258.0
HKD1_k127_27393_3 esterase lipase - - - 0.0000000008085 64.0
HKD1_k127_2745222_0 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 401.0
HKD1_k127_2745222_1 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 342.0
HKD1_k127_2745222_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 329.0
HKD1_k127_2745222_3 May be involved in the transport of PQQ or its precursor to the periplasm K06136 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 292.0
HKD1_k127_2745222_5 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000001303 119.0
HKD1_k127_2745222_6 Pyrroloquinoline quinone biosynthesis protein D K06138 - - 0.0000000001757 72.0
HKD1_k127_2747778_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 471.0
HKD1_k127_2747778_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000007576 221.0
HKD1_k127_2758961_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.786e-265 824.0
HKD1_k127_2758961_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000006895 250.0
HKD1_k127_2758961_2 Predicted membrane protein (DUF2254) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000006538 166.0
HKD1_k127_2775929_0 DNA helicase K03656,K03657 - 3.6.4.12 1.155e-204 673.0
HKD1_k127_2775929_1 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 447.0
HKD1_k127_2775929_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 423.0
HKD1_k127_2775929_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000002248 183.0
HKD1_k127_278258_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000003638 209.0
HKD1_k127_278258_1 Glycosyl transferase family 2 - - - 0.00000000152 60.0
HKD1_k127_2792480_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 312.0
HKD1_k127_2792480_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000639 175.0
HKD1_k127_2792480_3 function. Source PGD - - - 0.0002748 54.0
HKD1_k127_2799121_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004375 277.0
HKD1_k127_2799121_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000651 262.0
HKD1_k127_2799121_2 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000002792 209.0
HKD1_k127_2825050_0 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001621 263.0
HKD1_k127_2825050_1 Histidine kinase - - - 0.000000000000000000000000000000000000000187 155.0
HKD1_k127_2825050_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000004364 133.0
HKD1_k127_2825050_3 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000001929 119.0
HKD1_k127_2851483_0 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 392.0
HKD1_k127_2851483_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 370.0
HKD1_k127_2851483_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000001281 244.0
HKD1_k127_2851483_4 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000004659 173.0
HKD1_k127_2851483_5 stigma-specific Stig1 family protein - GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006952,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009751,GO:0009753,GO:0009755,GO:0009791,GO:0009863,GO:0009867,GO:0009889,GO:0009987,GO:0010033,GO:0010035,GO:0010154,GO:0010193,GO:0010337,GO:0010565,GO:0010817,GO:0010941,GO:0010942,GO:0014070,GO:0019216,GO:0019217,GO:0019222,GO:0022414,GO:0023052,GO:0031323,GO:0031326,GO:0032350,GO:0032501,GO:0032502,GO:0032870,GO:0035690,GO:0042221,GO:0042304,GO:0042493,GO:0042742,GO:0043207,GO:0044421,GO:0046677,GO:0046885,GO:0046890,GO:0048316,GO:0048518,GO:0048522,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0061458,GO:0062012,GO:0065007,GO:0065008,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071395,GO:0071407,GO:0071446,GO:0071495,GO:0080090,GO:0080140,GO:0080141,GO:0080142,GO:0098542,GO:1901700,GO:1901701 - 0.000000000000000002619 98.0
HKD1_k127_2855283_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1303.0
HKD1_k127_2855283_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 4.421e-246 762.0
HKD1_k127_2855283_10 - - - - 0.0000000000000000005468 95.0
HKD1_k127_2855283_11 PFAM Peptidase M16 inactive domain - - - 0.0000000000152 78.0
HKD1_k127_2855283_12 Type ii and iii secretion system protein - - - 0.00001055 57.0
HKD1_k127_2855283_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 357.0
HKD1_k127_2855283_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 361.0
HKD1_k127_2855283_4 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 356.0
HKD1_k127_2855283_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 296.0
HKD1_k127_2855283_6 Metallo-beta-lactamase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000018 301.0
HKD1_k127_2855283_7 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000001328 243.0
HKD1_k127_2855283_8 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000002216 116.0
HKD1_k127_2855283_9 - - - - 0.00000000000000000000005543 106.0
HKD1_k127_2865017_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1023.0
HKD1_k127_2865017_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 477.0
HKD1_k127_2865017_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 468.0
HKD1_k127_2865017_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 352.0
HKD1_k127_2865017_4 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006499 282.0
HKD1_k127_2865017_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000008632 259.0
HKD1_k127_2865017_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000001763 198.0
HKD1_k127_2870515_0 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000001454 212.0
HKD1_k127_2870515_1 YCII-related domain K09780 - - 0.000000000000000000000000000004575 133.0
HKD1_k127_2870515_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000003729 120.0
HKD1_k127_2870515_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000002632 115.0
HKD1_k127_2870515_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000007281 101.0
HKD1_k127_2870515_6 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000002013 78.0
HKD1_k127_2885435_0 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 439.0
HKD1_k127_2885435_1 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002975 238.0
HKD1_k127_2885435_2 Surface antigen - - - 0.0000000000000000000000000000000000000000000000003361 198.0
HKD1_k127_2885435_3 Alcohol dehydrogenase GroES-like domain K00001,K13953 - 1.1.1.1 0.0000000003083 68.0
HKD1_k127_2888083_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.902e-254 807.0
HKD1_k127_2888083_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 451.0
HKD1_k127_2888083_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 316.0
HKD1_k127_2888083_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000002303 185.0
HKD1_k127_2888083_4 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000009561 153.0
HKD1_k127_2888083_5 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.0000000000000000000000000002482 132.0
HKD1_k127_2888083_6 PEGA domain - - - 0.00000000000000000000002222 111.0
HKD1_k127_2888083_7 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000001189 102.0
HKD1_k127_2888083_8 acetyltransferase - - - 0.000000000000000000002834 109.0
HKD1_k127_2888083_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000007665 71.0
HKD1_k127_2910733_0 Glycosyl hydrolases family 31 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009133 312.0
HKD1_k127_2910733_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000004491 96.0
HKD1_k127_2916886_0 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 505.0
HKD1_k127_2916886_1 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 421.0
HKD1_k127_2916886_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000004509 182.0
HKD1_k127_291738_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1361.0
HKD1_k127_291738_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 581.0
HKD1_k127_291738_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
HKD1_k127_291738_3 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000007998 267.0
HKD1_k127_291738_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000001972 172.0
HKD1_k127_2917409_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 569.0
HKD1_k127_2917409_10 HEAT repeat - - - 0.00000000000000000000558 103.0
HKD1_k127_2917409_11 - - - - 0.00003477 54.0
HKD1_k127_2917409_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 359.0
HKD1_k127_2917409_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 314.0
HKD1_k127_2917409_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
HKD1_k127_2917409_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000897 170.0
HKD1_k127_2917409_6 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000004504 166.0
HKD1_k127_2917409_7 Chemotaxis protein CheY K03413 - - 0.0000000000000000000000000000000000000002138 154.0
HKD1_k127_2917409_8 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000004306 155.0
HKD1_k127_2917409_9 Methyltransferase domain - - - 0.0000000000000000000003734 110.0
HKD1_k127_2924929_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 479.0
HKD1_k127_2924929_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 388.0
HKD1_k127_2924929_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004245 257.0
HKD1_k127_2939938_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000001499 232.0
HKD1_k127_2939938_1 Thioredoxin-like - - - 0.00000000000000000000000000000000005742 152.0
HKD1_k127_2939938_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000002818 100.0
HKD1_k127_2940129_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 600.0
HKD1_k127_2940129_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004309 276.0
HKD1_k127_2940129_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000002813 227.0
HKD1_k127_2940129_3 - - - - 0.0000000000000000000000000000000000000000000000000000002273 220.0
HKD1_k127_2940129_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000003891 162.0
HKD1_k127_2940129_5 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000000000000001761 137.0
HKD1_k127_2940129_6 Major Facilitator Superfamily - - - 0.000001364 60.0
HKD1_k127_2942155_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.546e-306 951.0
HKD1_k127_2942155_1 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 385.0
HKD1_k127_2942155_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 375.0
HKD1_k127_2942155_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 327.0
HKD1_k127_2942155_4 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000004334 231.0
HKD1_k127_2942155_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000002416 167.0
HKD1_k127_2942155_6 PGAP1-like protein K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000114 165.0
HKD1_k127_2942155_7 Protein of unknown function (DUF559) - - - 0.0000000000000000000005179 100.0
HKD1_k127_294225_0 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 398.0
HKD1_k127_294225_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 381.0
HKD1_k127_294225_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001385 187.0
HKD1_k127_294225_5 transcriptional - - - 0.0000000000000000000000000000001486 134.0
HKD1_k127_294225_6 cyclic nucleotide-binding - - - 0.00000000000000000000000000007255 135.0
HKD1_k127_294225_7 SEC-C motif - - - 0.000000000000000000006831 96.0
HKD1_k127_294225_8 FHA domain - - - 0.0000009014 58.0
HKD1_k127_2943457_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 465.0
HKD1_k127_2943457_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000003655 142.0
HKD1_k127_2943457_2 IgGFc binding protein - - - 0.0000000000385 65.0
HKD1_k127_2945445_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 424.0
HKD1_k127_2945445_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 388.0
HKD1_k127_2945445_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 301.0
HKD1_k127_2956646_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 308.0
HKD1_k127_2956646_1 protein contain chitin-binding domain type 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000105 259.0
HKD1_k127_2956646_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001069 205.0
HKD1_k127_2956646_3 Heat shock 70 kDa protein - - - 0.00000000000000000000000000007888 123.0
HKD1_k127_2956646_4 DnaJ molecular chaperone homology domain - - - 0.00000001839 64.0
HKD1_k127_2956646_5 - - - - 0.0000005034 61.0
HKD1_k127_2959819_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 473.0
HKD1_k127_2959819_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009128 281.0
HKD1_k127_2959819_2 Peptidylprolyl isomerase K09569,K09577 GO:0000322,GO:0000323,GO:0000324,GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005783,GO:0005789,GO:0006457,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031984,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0061077,GO:0071704,GO:0097159,GO:0098827,GO:0140096,GO:1901363,GO:1901564 5.2.1.8 0.000000000000000000000000002802 115.0
HKD1_k127_2959819_3 cheY-homologous receiver domain - - - 0.000000000000000000000002378 112.0
HKD1_k127_2962360_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 471.0
HKD1_k127_2962360_1 slime layer polysaccharide biosynthetic process K16710 - - 0.0000000000000000000000000000000001329 154.0
HKD1_k127_2962360_2 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000001413 135.0
HKD1_k127_2963270_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 9.328e-234 747.0
HKD1_k127_2963270_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 2.447e-211 675.0
HKD1_k127_2963270_10 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000005017 57.0
HKD1_k127_2963270_11 chitin catabolic process - - - 0.0009127 49.0
HKD1_k127_2963270_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 370.0
HKD1_k127_2963270_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 323.0
HKD1_k127_2963270_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 327.0
HKD1_k127_2963270_5 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
HKD1_k127_2963270_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000003713 140.0
HKD1_k127_2963270_7 Has antibacterial activity - GO:0000270,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016192,GO:0016787,GO:0016798,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0061783,GO:0071704,GO:0097708,GO:0098542,GO:0098657,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000009748 109.0
HKD1_k127_2963270_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000001403 97.0
HKD1_k127_2963270_9 - - - - 0.0000000000000000002065 95.0
HKD1_k127_2965895_0 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 477.0
HKD1_k127_2965895_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000005903 192.0
HKD1_k127_2979383_0 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 512.0
HKD1_k127_2979383_3 Nad-dependent epimerase dehydratase K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000002022 74.0
HKD1_k127_2979383_4 Protein conserved in bacteria - - - 0.00000179 59.0
HKD1_k127_2979383_5 Cell division protein FtsI - - - 0.0001318 53.0
HKD1_k127_2982297_0 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 441.0
HKD1_k127_2982297_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 314.0
HKD1_k127_2982297_2 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000144 204.0
HKD1_k127_2982297_3 Tetratricopeptide repeat - - - 0.00000000003393 76.0
HKD1_k127_2982848_0 4Fe-4S dicluster domain - - - 8.157e-306 952.0
HKD1_k127_2982848_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000002561 203.0
HKD1_k127_2982848_2 GAF domain - - - 0.00000000000000000000000000000002321 143.0
HKD1_k127_2982848_3 Protease prsW family - - - 0.0000000000000000000000000000000558 131.0
HKD1_k127_2982848_5 protease with the C-terminal PDZ domain - - - 0.000000000000000003234 99.0
HKD1_k127_2982848_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000001292 71.0
HKD1_k127_2982848_7 Photosynthesis system II assembly factor YCF48 - - - 0.0000000001389 75.0
HKD1_k127_2984371_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
HKD1_k127_2984371_1 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000008565 158.0
HKD1_k127_2984371_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000001679 157.0
HKD1_k127_2984371_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000007382 147.0
HKD1_k127_2984371_5 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.00000009954 62.0
HKD1_k127_2984371_6 Tricorn protease homolog K08676 - - 0.00001956 57.0
HKD1_k127_300904_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.418e-222 706.0
HKD1_k127_300904_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 354.0
HKD1_k127_300904_2 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000004319 136.0
HKD1_k127_300904_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000005406 108.0
HKD1_k127_3010538_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 617.0
HKD1_k127_3010538_1 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001013 257.0
HKD1_k127_3010538_2 pilus assembly protein PilW K02672 - - 0.0000000000000000000004129 112.0
HKD1_k127_3010538_3 protein transport across the cell outer membrane K02246,K08084 - - 0.0000000000000002342 91.0
HKD1_k127_3010538_4 type IV pilus modification protein PilV K02671,K02681 - - 0.000000000000001046 90.0
HKD1_k127_3024468_0 Family membership - - - 6.091e-302 970.0
HKD1_k127_3024468_1 kinase activity K01007 - 2.7.9.2 1.365e-250 800.0
HKD1_k127_3024468_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 602.0
HKD1_k127_3024468_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 447.0
HKD1_k127_3024468_4 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 - - 0.00000000000000000000000000000000000000000000001177 190.0
HKD1_k127_3024468_6 - - - - 0.0000000002284 66.0
HKD1_k127_3031045_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 2.016e-222 741.0
HKD1_k127_3031045_1 Peptidase family M28 - - - 0.0000000000000000000000000000000006356 141.0
HKD1_k127_3031045_2 exodeoxyribonuclease I activity K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000002757 108.0
HKD1_k127_3031045_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000001101 64.0
HKD1_k127_3041279_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 386.0
HKD1_k127_3041279_1 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 324.0
HKD1_k127_3041279_2 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000001054 211.0
HKD1_k127_3041279_3 fatty acid desaturase - - - 0.00000002354 57.0
HKD1_k127_3045879_0 uridine kinase K00855 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 375.0
HKD1_k127_3045879_1 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000002224 182.0
HKD1_k127_3045879_2 - - - - 0.0000000000000000000000008176 120.0
HKD1_k127_3045879_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000001925 108.0
HKD1_k127_3045879_4 Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000001062 106.0
HKD1_k127_3048921_0 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007725 259.0
HKD1_k127_3048921_1 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000008266 234.0
HKD1_k127_3048921_2 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000003113 178.0
HKD1_k127_305001_0 Histidine kinase - - - 0.0 1265.0
HKD1_k127_305001_1 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000991 145.0
HKD1_k127_305001_2 helix_turn_helix, Lux Regulon - - - 0.00000000001445 74.0
HKD1_k127_305687_0 Required for chromosome condensation and partitioning K03529 - - 3.104e-220 727.0
HKD1_k127_305687_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 514.0
HKD1_k127_305687_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000006145 270.0
HKD1_k127_305687_4 - - - - 0.0000000000000000000000000000000000000001877 169.0
HKD1_k127_305687_5 protein conserved in bacteria - - - 0.000000000000000000001521 97.0
HKD1_k127_305687_6 MerR HTH family regulatory protein - - - 0.000000000000001892 86.0
HKD1_k127_305687_8 - - - - 0.00000134 57.0
HKD1_k127_3061337_0 Voltage gated chloride channel - - - 4.948e-197 634.0
HKD1_k127_3061337_1 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000003362 138.0
HKD1_k127_3061337_2 Pfam:RRM_6 - - - 0.000000000000000000000000000009062 120.0
HKD1_k127_3061337_4 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000008321 98.0
HKD1_k127_3067415_0 transferase activity, transferring glycosyl groups K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 610.0
HKD1_k127_3067415_1 Glycosyltransferase Family 4 K14335 - - 0.0000000000000000000000000000000000000000000000000000008356 207.0
HKD1_k127_3067415_2 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000001717 196.0
HKD1_k127_3067415_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000001233 151.0
HKD1_k127_3067415_4 deacetylase K06986 - - 0.000000000000000000000003188 111.0
HKD1_k127_3067415_5 - - - - 0.000000000002085 79.0
HKD1_k127_3089601_0 Dihydropyrimidinase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 594.0
HKD1_k127_3089601_1 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 345.0
HKD1_k127_3089601_2 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000008981 250.0
HKD1_k127_3089601_3 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000004809 224.0
HKD1_k127_3089601_4 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000003777 182.0
HKD1_k127_3089601_5 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000000000000000000000000000000006844 152.0
HKD1_k127_3117711_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 374.0
HKD1_k127_3117711_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000102 225.0
HKD1_k127_3117711_2 Cation efflux family - - - 0.0000000000000000000000000000000000000000009403 166.0
HKD1_k127_3117711_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000005648 120.0
HKD1_k127_3117711_4 Predicted membrane protein (DUF2085) - - - 0.000000000000000003824 98.0
HKD1_k127_3117711_5 spectrin binding K15108 - - 0.0001035 53.0
HKD1_k127_3127663_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 499.0
HKD1_k127_3127663_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 358.0
HKD1_k127_3127663_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003325 223.0
HKD1_k127_3127663_3 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000000000000004279 232.0
HKD1_k127_3127663_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000001765 153.0
HKD1_k127_3127663_5 - - - - 0.000000001394 71.0
HKD1_k127_3130951_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 493.0
HKD1_k127_3130951_1 FCD - - - 0.0000000002711 66.0
HKD1_k127_3130951_2 - - - - 0.0000412 57.0
HKD1_k127_3141661_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 623.0
HKD1_k127_3141661_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 421.0
HKD1_k127_3141661_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 360.0
HKD1_k127_3141661_3 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 264.0
HKD1_k127_3141661_4 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000003749 201.0
HKD1_k127_3141661_6 Acid phosphatase homologues - - - 0.000000000000000000005493 106.0
HKD1_k127_3141661_7 - - - - 0.000000000005814 78.0
HKD1_k127_3141661_9 Forkhead associated domain - - - 0.0001173 54.0
HKD1_k127_3160313_0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000005458 263.0
HKD1_k127_3160313_1 transcriptional regulator K03719,K05800 - - 0.000000000000000000000000000000006012 132.0
HKD1_k127_3160313_2 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000005761 132.0
HKD1_k127_3160313_3 amine dehydrogenase activity - - - 0.000000001059 72.0
HKD1_k127_3160313_4 SMI1-KNR4 cell-wall - - - 0.0001023 55.0
HKD1_k127_3165048_0 UvrD-like helicase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007985 292.0
HKD1_k127_3165048_1 lipase class 2 - - - 0.00000000000000000007476 100.0
HKD1_k127_3165048_2 zinc-ribbon domain - - - 0.0000000000003922 76.0
HKD1_k127_3165048_3 amine dehydrogenase activity - - - 0.000000000000423 81.0
HKD1_k127_317021_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.822e-288 891.0
HKD1_k127_317021_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 362.0
HKD1_k127_317021_2 - - - - 0.00000000000000000000000000000000000000000000000000001964 192.0
HKD1_k127_317021_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000003484 53.0
HKD1_k127_317021_4 PDZ DHR GLGF domain protein K08372 - - 0.0003317 53.0
HKD1_k127_317474_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 608.0
HKD1_k127_317474_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000001046 211.0
HKD1_k127_317474_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00002423 57.0
HKD1_k127_3177514_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001661 287.0
HKD1_k127_3179803_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.928e-217 692.0
HKD1_k127_3179803_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 458.0
HKD1_k127_3179803_2 protein related to plant photosystem II stability assembly factor - - - 0.0000003275 64.0
HKD1_k127_3179803_3 Beta-L-arabinofuranosidase, GH127 - - - 0.0000003944 61.0
HKD1_k127_3185365_0 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 550.0
HKD1_k127_3185365_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000006302 245.0
HKD1_k127_3185365_2 chlorophyll binding K21218 - - 0.00000000000000000000003668 105.0
HKD1_k127_3185365_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000003443 107.0
HKD1_k127_3186171_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 1.316e-258 848.0
HKD1_k127_3186171_1 Amidohydrolase family - - - 6.127e-256 801.0
HKD1_k127_3186171_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000002858 83.0
HKD1_k127_3186171_11 PFAM outer membrane efflux protein K15725 - - 0.000000005065 68.0
HKD1_k127_3186171_12 Beta-galactosidase - - - 0.00001657 55.0
HKD1_k127_3186171_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 381.0
HKD1_k127_3186171_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004835 269.0
HKD1_k127_3186171_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
HKD1_k127_3186171_5 - - - - 0.0000000000000000000000000000000000000000000000000000000007689 205.0
HKD1_k127_3186171_6 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000937 220.0
HKD1_k127_3186171_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000009987 164.0
HKD1_k127_3186171_8 Biotin-lipoyl like K15727 - - 0.0000000000000000000000000004355 132.0
HKD1_k127_3186171_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001492 104.0
HKD1_k127_3186246_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 446.0
HKD1_k127_3186246_1 Protein of unknown function (DUF1595) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003755 301.0
HKD1_k127_3186246_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001645 256.0
HKD1_k127_3186246_3 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000005898 195.0
HKD1_k127_3186246_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000001906 147.0
HKD1_k127_3186246_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000002057 128.0
HKD1_k127_3198051_0 Multicopper oxidase K00368 - 1.7.2.1 1.275e-214 677.0
HKD1_k127_3198051_1 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) - - - 1.848e-198 657.0
HKD1_k127_3198051_10 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000006301 163.0
HKD1_k127_3198051_11 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000001059 168.0
HKD1_k127_3198051_12 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000001517 138.0
HKD1_k127_3198051_13 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000001193 136.0
HKD1_k127_3198051_14 YceI-like domain - - - 0.00000000000000000000000000000005755 132.0
HKD1_k127_3198051_15 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.00000000000000000000000000000006497 142.0
HKD1_k127_3198051_16 SCO1/SenC K07152 - - 0.0000000000000000000000000001615 131.0
HKD1_k127_3198051_17 HlyD family secretion protein K01993 - - 0.000000000000000000000009364 113.0
HKD1_k127_3198051_18 - - - - 0.000000000000000000005115 107.0
HKD1_k127_3198051_19 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000108 86.0
HKD1_k127_3198051_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 353.0
HKD1_k127_3198051_20 transcriptional regulator K09017 - - 0.0000000003284 71.0
HKD1_k127_3198051_21 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000004323 62.0
HKD1_k127_3198051_23 Hemerythrin HHE cation binding domain protein K09155 - - 0.00005705 54.0
HKD1_k127_3198051_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 299.0
HKD1_k127_3198051_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 310.0
HKD1_k127_3198051_6 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000124 262.0
HKD1_k127_3198051_7 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000001231 218.0
HKD1_k127_3198051_8 transcriptional - - - 0.0000000000000000000000000000000000000000000002404 176.0
HKD1_k127_3198051_9 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000003734 173.0
HKD1_k127_3213101_0 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 310.0
HKD1_k127_3213101_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000006276 178.0
HKD1_k127_3213101_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000007264 58.0
HKD1_k127_3222672_0 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 464.0
HKD1_k127_3222672_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HKD1_k127_3222672_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
HKD1_k127_3222672_3 - - - - 0.000000000000000000000000185 114.0
HKD1_k127_3222965_0 DEAD DEAH box helicase - - - 1.778e-236 764.0
HKD1_k127_3222965_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
HKD1_k127_3224251_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.98e-200 637.0
HKD1_k127_3224251_1 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 462.0
HKD1_k127_3224251_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000008253 233.0
HKD1_k127_3224251_3 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.00000000000000000000000003258 126.0
HKD1_k127_3224251_4 histone H2A K63-linked ubiquitination - - - 0.0000000000008059 70.0
HKD1_k127_3226158_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 4.901e-260 824.0
HKD1_k127_3226158_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000001379 203.0
HKD1_k127_3226158_2 Belongs to the thiolase family - - - 0.00000000000000000000000000002942 136.0
HKD1_k127_3226158_3 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000004207 49.0
HKD1_k127_3231585_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 596.0
HKD1_k127_3231585_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 439.0
HKD1_k127_3231585_2 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HKD1_k127_3238207_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 398.0
HKD1_k127_3238207_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 320.0
HKD1_k127_3238225_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 451.0
HKD1_k127_3238225_1 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000005873 134.0
HKD1_k127_3256554_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 531.0
HKD1_k127_3256554_1 COG0326 Molecular chaperone, HSP90 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 334.0
HKD1_k127_3256554_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 315.0
HKD1_k127_3259479_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 610.0
HKD1_k127_3259479_1 amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 335.0
HKD1_k127_3259479_2 Isochorismatase family - - - 0.000000000000000000000001519 113.0
HKD1_k127_3259479_3 protein kinase activity - - - 0.000000000003933 79.0
HKD1_k127_3259479_4 zinc-ribbon domain - - - 0.0000000002202 69.0
HKD1_k127_3269577_0 DNA polymerase K02337,K14162 - 2.7.7.7 5.146e-284 919.0
HKD1_k127_3269577_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002298 243.0
HKD1_k127_3269577_3 oxidoreductase activity K07114 - - 0.000000000000000000000000005229 127.0
HKD1_k127_3272351_0 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 426.0
HKD1_k127_3272351_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 346.0
HKD1_k127_3272351_10 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000003217 132.0
HKD1_k127_3272351_11 Serine aminopeptidase, S33 - - - 0.000000000003536 79.0
HKD1_k127_3272351_13 PFAM Peptidase family M28 - - - 0.00002093 56.0
HKD1_k127_3272351_2 SMART Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000005924 218.0
HKD1_k127_3272351_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000002459 185.0
HKD1_k127_3272351_4 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000005411 182.0
HKD1_k127_3272351_5 protein kinase activity - - - 0.00000000000000000000000000000000000000000000001141 181.0
HKD1_k127_3272351_6 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000005256 178.0
HKD1_k127_3272351_7 COG1121 ABC-type Mn Zn transport systems ATPase component K09817 - - 0.0000000000000000000000000000000000000000000006164 181.0
HKD1_k127_3272351_8 Glutaredoxin - - - 0.0000000000000000000000000000000000000533 146.0
HKD1_k127_3272351_9 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000236 119.0
HKD1_k127_3276664_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.366e-284 897.0
HKD1_k127_3276664_1 Participates in both transcription termination and antitermination K02600 - - 1.754e-228 716.0
HKD1_k127_3276664_10 PFAM PEGA domain - - - 0.00000000000000001626 95.0
HKD1_k127_3276664_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000009776 71.0
HKD1_k127_3276664_13 Phospholipid methyltransferase - - - 0.00000001528 63.0
HKD1_k127_3276664_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 467.0
HKD1_k127_3276664_3 ATPase (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 381.0
HKD1_k127_3276664_4 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005238 283.0
HKD1_k127_3276664_5 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000001028 179.0
HKD1_k127_3276664_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000001343 173.0
HKD1_k127_3276664_7 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000001323 134.0
HKD1_k127_3276664_9 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000001504 94.0
HKD1_k127_3289641_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000002099 205.0
HKD1_k127_3289641_1 Protein kinase domain - - - 0.0000000000000000000000000000003087 125.0
HKD1_k127_3289641_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000005091 73.0
HKD1_k127_3289641_3 Zinc-dependent metalloprotease - - - 0.00000001106 59.0
HKD1_k127_3290668_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 567.0
HKD1_k127_3290668_1 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 335.0
HKD1_k127_3290668_3 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000008089 240.0
HKD1_k127_3290668_4 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000274 129.0
HKD1_k127_3290668_6 lipoprotein receptor-related protein K04550,K20049 GO:0001568,GO:0001701,GO:0001944,GO:0002020,GO:0003205,GO:0003279,GO:0003674,GO:0005041,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0005887,GO:0006066,GO:0006629,GO:0006810,GO:0006897,GO:0006898,GO:0006909,GO:0007154,GO:0007165,GO:0007186,GO:0007205,GO:0007275,GO:0007399,GO:0007507,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008283,GO:0009653,GO:0009790,GO:0009792,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009968,GO:0009987,GO:0010517,GO:0010604,GO:0010640,GO:0010642,GO:0010646,GO:0010648,GO:0010721,GO:0010874,GO:0010875,GO:0010941,GO:0010942,GO:0010975,GO:0010977,GO:0012505,GO:0014910,GO:0014912,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016125,GO:0016192,GO:0016323,GO:0016964,GO:0019222,GO:0019899,GO:0022008,GO:0023051,GO:0023052,GO:0023057,GO:0030100,GO:0030111,GO:0030135,GO:0030136,GO:0030154,GO:0030178,GO:0030228,GO:0030276,GO:0030334,GO:0030336,GO:0030425,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031344,GO:0031345,GO:0031410,GO:0031982,GO:0032050,GO:0032092,GO:0032268,GO:0032270,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032429,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0034185,GO:0035239,GO:0035295,GO:0035904,GO:0035909,GO:0036477,GO:0038024,GO:0040012,GO:0040013,GO:0042176,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043235,GO:0043277,GO:0043393,GO:0043523,GO:0043524,GO:0044093,GO:0044238,GO:0044281,GO:0044297,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045056,GO:0045184,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045732,GO:0045807,GO:0046872,GO:0048471,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048844,GO:0048856,GO:0048869,GO:0050750,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051098,GO:0051099,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051270,GO:0051271,GO:0051336,GO:0051493,GO:0051716,GO:0051960,GO:0051961,GO:0060191,GO:0060255,GO:0060284,GO:0060341,GO:0060548,GO:0060627,GO:0060840,GO:0060976,GO:0065007,GO:0065009,GO:0070201,GO:0070325,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072358,GO:0072359,GO:0080090,GO:0090087,GO:0097242,GO:0097447,GO:0097458,GO:0097708,GO:0098590,GO:0098657,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901215,GO:1901360,GO:1901615,GO:1902652,GO:1903076,GO:1903078,GO:1903362,GO:1903364,GO:1903827,GO:1903829,GO:1904350,GO:1904352,GO:1904375,GO:1904377,GO:1904951,GO:1905165,GO:1905167,GO:1905475,GO:1905477,GO:1905952,GO:1905954,GO:2000026,GO:2000145,GO:2000146,GO:2000586,GO:2000587 - 0.0004501 51.0
HKD1_k127_3291724_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 533.0
HKD1_k127_3291724_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 364.0
HKD1_k127_3291724_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 365.0
HKD1_k127_3293678_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 533.0
HKD1_k127_3293678_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 477.0
HKD1_k127_3293678_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 420.0
HKD1_k127_3293678_4 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000001278 90.0
HKD1_k127_3293678_5 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000005277 92.0
HKD1_k127_3293678_6 Belongs to the peptidase S8 family - - - 0.0000000002486 71.0
HKD1_k127_3293678_7 EamA-like transporter family - - - 0.0000002613 61.0
HKD1_k127_3293678_8 Type VI secretion system effector (Hcp1 K11903 - - 0.000002395 57.0
HKD1_k127_3302002_0 FAD binding domain - - - 0.00000000000000000000000000000000000002708 164.0
HKD1_k127_3302842_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 299.0
HKD1_k127_3302842_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000004483 235.0
HKD1_k127_3302842_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000003095 164.0
HKD1_k127_3302842_4 peptidyl-tyrosine sulfation - - - 0.000000000000000003343 100.0
HKD1_k127_3302842_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000001714 70.0
HKD1_k127_3310048_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 427.0
HKD1_k127_3310048_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 408.0
HKD1_k127_3310048_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004906 283.0
HKD1_k127_3310048_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 263.0
HKD1_k127_3310048_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000009902 120.0
HKD1_k127_3310048_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000008053 78.0
HKD1_k127_3310048_9 - - - - 0.00001841 53.0
HKD1_k127_3319575_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 455.0
HKD1_k127_3319575_1 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 298.0
HKD1_k127_3319575_2 vancomycin resistance protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
HKD1_k127_3319575_3 amine dehydrogenase activity - - - 0.0000000003285 72.0
HKD1_k127_3324615_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 505.0
HKD1_k127_3324615_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 308.0
HKD1_k127_3324615_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
HKD1_k127_3324615_3 - - - - 0.000000000000000000000000000000000006005 144.0
HKD1_k127_3324615_4 VIT family - - - 0.000000000000000000000001 121.0
HKD1_k127_3324615_5 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000001137 117.0
HKD1_k127_3329140_0 protein kinase activity - - - 4.003e-213 691.0
HKD1_k127_3329140_1 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 510.0
HKD1_k127_3329140_2 copper-translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
HKD1_k127_3329140_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000004678 221.0
HKD1_k127_3329140_4 Glucose-methanol-choline (GMC) oxidoreductase NAD binding site - - - 0.00000000000000000000000000000000000000000000000008394 182.0
HKD1_k127_3333416_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 481.0
HKD1_k127_3333416_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 378.0
HKD1_k127_3333416_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000001351 118.0
HKD1_k127_3333416_11 - - - - 0.0000000002504 70.0
HKD1_k127_3333416_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000001273 59.0
HKD1_k127_3333416_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 390.0
HKD1_k127_3333416_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 358.0
HKD1_k127_3333416_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 341.0
HKD1_k127_3333416_5 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000001024 268.0
HKD1_k127_3333416_7 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000002199 195.0
HKD1_k127_3333416_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000003172 121.0
HKD1_k127_3337315_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 3.602e-202 672.0
HKD1_k127_3337315_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.454e-196 617.0
HKD1_k127_3337315_10 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000005256 84.0
HKD1_k127_3337315_2 Biotin carboxylase K01961,K01968 - 6.3.4.14,6.4.1.2,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 569.0
HKD1_k127_3337315_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 499.0
HKD1_k127_3337315_4 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 456.0
HKD1_k127_3337315_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 447.0
HKD1_k127_3337315_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001322 293.0
HKD1_k127_3337315_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000002916 214.0
HKD1_k127_3337315_8 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000003691 196.0
HKD1_k127_3337315_9 COG0563 Adenylate kinase and related kinases - - - 0.0000000000000000000000000000000000000000000000004832 188.0
HKD1_k127_3337832_0 acyl-CoA dehydrogenase K09456,K20035 - - 5.519e-256 804.0
HKD1_k127_3337832_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 453.0
HKD1_k127_3337832_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 447.0
HKD1_k127_3337832_3 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008586 278.0
HKD1_k127_3337832_4 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HKD1_k127_3337832_5 COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.000000000000000000000000000000000000000000000000000000000001526 216.0
HKD1_k127_3337832_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003453 160.0
HKD1_k127_3337832_7 - - - - 0.00000000005404 69.0
HKD1_k127_3337832_9 repeat-containing protein - - - 0.00001291 57.0
HKD1_k127_3339245_0 Belongs to the OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 425.0
HKD1_k127_3339245_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000004317 148.0
HKD1_k127_3339245_2 Membrane K08988 - - 0.00000000000000000000000000004403 125.0
HKD1_k127_3339755_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 486.0
HKD1_k127_3339755_1 acetyltransferase involved in intracellular survival and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003466 286.0
HKD1_k127_3339755_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002093 269.0
HKD1_k127_3339755_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000002169 250.0
HKD1_k127_3339755_4 - - - - 0.0000001538 63.0
HKD1_k127_3339755_5 negative regulation of translational initiation - - - 0.0000006783 62.0
HKD1_k127_3344903_0 ATPase activity K01990 - - 1.038e-228 726.0
HKD1_k127_3344903_1 ABC-2 family transporter protein K01992,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 357.0
HKD1_k127_3344903_10 Tetratricopeptide repeat - - - 0.0000000000009566 81.0
HKD1_k127_3344903_11 SMI1 / KNR4 family - - - 0.000001348 61.0
HKD1_k127_3344903_2 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 314.0
HKD1_k127_3344903_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007471 280.0
HKD1_k127_3344903_4 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001661 251.0
HKD1_k127_3344903_5 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000001649 235.0
HKD1_k127_3344903_6 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000002276 206.0
HKD1_k127_3344903_7 - - - - 0.0000000000000000000000000000000000000006389 156.0
HKD1_k127_3344903_8 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000003808 125.0
HKD1_k127_3344903_9 Beta-lactamase class C - - - 0.000000000000000000001567 105.0
HKD1_k127_3347780_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 328.0
HKD1_k127_3347780_1 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 335.0
HKD1_k127_3347780_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000004823 181.0
HKD1_k127_3347780_3 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000008579 126.0
HKD1_k127_3347780_4 acyl-coa-binding protein - - - 0.000000000000000000000000002679 119.0
HKD1_k127_3347780_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000004899 78.0
HKD1_k127_3353958_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004398 289.0
HKD1_k127_3353958_1 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000004584 204.0
HKD1_k127_3353958_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000002347 138.0
HKD1_k127_3354580_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 496.0
HKD1_k127_3354580_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 328.0
HKD1_k127_3354580_2 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006865 271.0
HKD1_k127_3354580_3 - - - - 0.0000000000000000000000000000000000000000000000000000001288 204.0
HKD1_k127_3354580_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000001247 147.0
HKD1_k127_3354580_5 - - - - 0.000000000000000000000000000003703 122.0
HKD1_k127_3354580_7 PFAM von Willebrand factor type A - - - 0.0000000000000004893 91.0
HKD1_k127_3356165_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007724 252.0
HKD1_k127_3356165_1 Low-density lipoprotein receptor domain class A - - - 0.0006895 50.0
HKD1_k127_3359049_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 443.0
HKD1_k127_3359049_1 COG3511 Phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000008396 229.0
HKD1_k127_336194_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 277.0
HKD1_k127_336194_1 Haem-NO-binding - - - 0.000000000000000000000000000000002322 135.0
HKD1_k127_336194_2 amine dehydrogenase activity - - - 0.00000000000000000000000000002745 136.0
HKD1_k127_336194_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000005326 72.0
HKD1_k127_3363095_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006644,GO:0006650,GO:0006656,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016054,GO:0016259,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019439,GO:0019510,GO:0019637,GO:0019752,GO:0031012,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0042219,GO:0042278,GO:0042454,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046128,GO:0046130,GO:0046395,GO:0046439,GO:0046470,GO:0046474,GO:0046483,GO:0046486,GO:0046498,GO:0046500,GO:0046700,GO:0051186,GO:0051187,GO:0055086,GO:0062039,GO:0062040,GO:0071704,GO:0072521,GO:0072523,GO:0090407,GO:0097164,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901657,GO:1901658 3.3.1.1 5.961e-197 639.0
HKD1_k127_3363095_1 Methyltransferase type 11 K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 295.0
HKD1_k127_3363095_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000009711 214.0
HKD1_k127_3363095_3 Protein conserved in bacteria - - - 0.000000000004118 71.0
HKD1_k127_3363095_4 Biopolymer transport protein ExbD/TolR - - - 0.0002369 54.0
HKD1_k127_3368430_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
HKD1_k127_3368430_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000003839 220.0
HKD1_k127_3368430_2 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000000000000000000001195 212.0
HKD1_k127_3368430_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000005351 113.0
HKD1_k127_3372680_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1069.0
HKD1_k127_3372680_1 AcrB/AcrD/AcrF family K15726 - - 1.794e-272 874.0
HKD1_k127_3372680_10 - - - - 0.00000000000000000000003781 113.0
HKD1_k127_3372680_11 PFAM Outer membrane efflux protein - - - 0.000000000000000000005342 109.0
HKD1_k127_3372680_12 Outer membrane efflux protein - - - 0.00000000000000000004133 102.0
HKD1_k127_3372680_13 - - - - 0.0000000000000009227 89.0
HKD1_k127_3372680_2 Transcriptional regulator K03655,K10439,K11708 - 3.6.4.12 2.075e-208 662.0
HKD1_k127_3372680_3 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 537.0
HKD1_k127_3372680_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 350.0
HKD1_k127_3372680_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009084 279.0
HKD1_k127_3372680_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000005993 231.0
HKD1_k127_3372680_7 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001503 242.0
HKD1_k127_3372680_8 Member of a two-component regulatory system K02484,K07644,K07645,K18143 GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001058 216.0
HKD1_k127_3372680_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000002125 128.0
HKD1_k127_3384930_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 453.0
HKD1_k127_3384930_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 430.0
HKD1_k127_3384930_10 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000003634 202.0
HKD1_k127_3384930_12 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000000000000001642 169.0
HKD1_k127_3384930_13 protein trimerization - - - 0.0000000000000000000000000000000000000005187 163.0
HKD1_k127_3384930_14 ThiS family K03636 - - 0.000000000000000000000000000000000005328 139.0
HKD1_k127_3384930_15 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000004611 143.0
HKD1_k127_3384930_16 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000004954 123.0
HKD1_k127_3384930_19 Bacterial Ig-like domain (group 2) - - - 0.00000005049 61.0
HKD1_k127_3384930_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 424.0
HKD1_k127_3384930_20 Aspartyl protease - - - 0.00002086 53.0
HKD1_k127_3384930_3 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 330.0
HKD1_k127_3384930_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
HKD1_k127_3384930_5 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000395 296.0
HKD1_k127_3384930_6 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000001446 253.0
HKD1_k127_3384930_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000006391 243.0
HKD1_k127_3384930_8 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
HKD1_k127_3384930_9 domain protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000004103 207.0
HKD1_k127_3389859_0 protein kinase activity - - - 1.56e-232 740.0
HKD1_k127_3389859_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.752e-206 652.0
HKD1_k127_3389859_10 PFAM Stress-induced bacterial acidophilic repeat motif - - - 0.0000000000003898 74.0
HKD1_k127_3389859_11 Winged helix DNA-binding domain - - - 0.0000000000036 72.0
HKD1_k127_3389859_13 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000004882 55.0
HKD1_k127_3389859_14 Protein of unknown function (DUF533) - - - 0.00001736 53.0
HKD1_k127_3389859_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 399.0
HKD1_k127_3389859_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 396.0
HKD1_k127_3389859_4 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005327 252.0
HKD1_k127_3389859_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000003984 199.0
HKD1_k127_3389859_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000002086 165.0
HKD1_k127_3389859_7 InterPro IPR007367 - - - 0.00000000000000000000000000009018 121.0
HKD1_k127_3389859_8 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000009736 109.0
HKD1_k127_3401556_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 518.0
HKD1_k127_3401556_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003113 278.0
HKD1_k127_3401556_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002032 271.0
HKD1_k127_3401556_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001298 194.0
HKD1_k127_3401556_4 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000000000000000000006397 145.0
HKD1_k127_3401556_5 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000003336 123.0
HKD1_k127_3401556_6 Stigma-specific protein, Stig1 - - - 0.0000000000000000000001264 111.0
HKD1_k127_3415778_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
HKD1_k127_3415778_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004427 290.0
HKD1_k127_3415778_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001284 202.0
HKD1_k127_3415778_5 Heavy-metal resistance - - - 0.0000000000000000001464 97.0
HKD1_k127_342926_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 421.0
HKD1_k127_342926_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 331.0
HKD1_k127_342926_2 - - - - 0.0000000000000000000000000000000000000000001157 168.0
HKD1_k127_342926_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000001432 98.0
HKD1_k127_3429374_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 7.247e-195 626.0
HKD1_k127_3429374_1 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 332.0
HKD1_k127_3429374_10 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000001188 84.0
HKD1_k127_3429374_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004797 282.0
HKD1_k127_3429374_3 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001103 260.0
HKD1_k127_3429374_4 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000002932 190.0
HKD1_k127_3429374_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000002333 200.0
HKD1_k127_3429374_6 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000007489 189.0
HKD1_k127_3429374_7 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000001575 181.0
HKD1_k127_3429374_8 Chromate resistance - - - 0.0000000000000000000000000008804 118.0
HKD1_k127_3429374_9 amine dehydrogenase activity - - - 0.0000000000000000001741 102.0
HKD1_k127_3441260_0 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 396.0
HKD1_k127_3441260_1 Binding-protein-dependent transport system inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 327.0
HKD1_k127_3441260_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000001087 225.0
HKD1_k127_3441260_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000009906 174.0
HKD1_k127_3441260_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0003116 44.0
HKD1_k127_3443086_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 1.604e-219 711.0
HKD1_k127_3443086_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
HKD1_k127_3445158_0 Diguanylate cyclase - - - 6.017e-220 719.0
HKD1_k127_3445158_1 belongs to the thioredoxin family K00384,K02453,K11912,K20543 - 1.8.1.9,2.7.11.1 0.00000000000000000000000000000000000000002443 167.0
HKD1_k127_3445158_2 PFAM Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000005365 122.0
HKD1_k127_3445158_3 Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0000000000000000000331 94.0
HKD1_k127_3445158_4 Psort location Cytoplasmic, score 8.96 - - - 0.00003246 56.0
HKD1_k127_3445491_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 392.0
HKD1_k127_3445491_1 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000002905 210.0
HKD1_k127_3445491_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001705 209.0
HKD1_k127_3445491_3 Phosphoesterase family K21302 - 3.1.3.64 0.00000000000000000000000000000000000367 155.0
HKD1_k127_3445491_4 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000004455 153.0
HKD1_k127_3445491_5 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000000000000004081 107.0
HKD1_k127_3445491_6 Rhodanese Homology Domain - - - 0.0000000000000000001135 93.0
HKD1_k127_3445491_8 mRNA, complete cds K06560 GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0042742,GO:0043207,GO:0050830,GO:0050896,GO:0051704,GO:0051707,GO:0098542 - 0.000003906 58.0
HKD1_k127_3447134_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 409.0
HKD1_k127_3447134_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 404.0
HKD1_k127_3447134_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 401.0
HKD1_k127_3447134_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 307.0
HKD1_k127_3447134_4 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000005784 168.0
HKD1_k127_3447134_5 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000003005 113.0
HKD1_k127_3447134_6 NUDIX domain - - - 0.0000000000000003051 88.0
HKD1_k127_3447134_7 PFAM Abortive infection protein - - - 0.0000000000000005478 87.0
HKD1_k127_3447134_8 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000002751 64.0
HKD1_k127_3450642_0 response regulator K07714 - - 1.561e-223 699.0
HKD1_k127_3450642_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 426.0
HKD1_k127_3450642_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 430.0
HKD1_k127_3450642_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000261 289.0
HKD1_k127_3450642_4 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002895 256.0
HKD1_k127_3450642_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000001634 199.0
HKD1_k127_3450642_6 Acyltransferase - - - 0.00000000000000000000000000003467 128.0
HKD1_k127_3450642_7 - - - - 0.000000000000000005525 94.0
HKD1_k127_3450642_8 - - - - 0.00000000002792 73.0
HKD1_k127_3455416_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 425.0
HKD1_k127_3455416_1 Belongs to the ompA family K20276 - - 0.0002569 51.0
HKD1_k127_3457646_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 602.0
HKD1_k127_3457646_1 alcohol dehydrogenase K00043 - 1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 452.0
HKD1_k127_3457646_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 377.0
HKD1_k127_3469293_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 564.0
HKD1_k127_3469293_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 507.0
HKD1_k127_3469293_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 466.0
HKD1_k127_3469293_3 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006565 288.0
HKD1_k127_3469293_4 - - - - 0.0000000000000000000000000000000000000000000002536 177.0
HKD1_k127_3473141_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 589.0
HKD1_k127_3473141_1 - - - - 0.0000000000001959 82.0
HKD1_k127_3483803_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 572.0
HKD1_k127_3483803_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 331.0
HKD1_k127_3483803_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007657 288.0
HKD1_k127_3483803_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000004712 244.0
HKD1_k127_3483803_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001494 237.0
HKD1_k127_3483803_5 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000004152 177.0
HKD1_k127_3483803_6 PilZ domain K02676 - - 0.00000000000000000000000000000000002103 139.0
HKD1_k127_3485662_0 ABC transporter K06147,K06148 - - 3.941e-247 804.0
HKD1_k127_3485662_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 357.0
HKD1_k127_3485662_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002348 252.0
HKD1_k127_3485662_3 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.00000000000000000001614 93.0
HKD1_k127_3492337_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 404.0
HKD1_k127_3492337_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
HKD1_k127_3492337_10 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000002891 207.0
HKD1_k127_3492337_11 acid phosphatase activity K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000002776 192.0
HKD1_k127_3492337_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000166 188.0
HKD1_k127_3492337_13 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000001036 177.0
HKD1_k127_3492337_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000004082 174.0
HKD1_k127_3492337_2 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 368.0
HKD1_k127_3492337_3 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 357.0
HKD1_k127_3492337_4 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 355.0
HKD1_k127_3492337_5 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 340.0
HKD1_k127_3492337_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 311.0
HKD1_k127_3492337_7 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006186 272.0
HKD1_k127_3492337_8 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005733 275.0
HKD1_k127_3492337_9 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000003741 237.0
HKD1_k127_350307_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 466.0
HKD1_k127_3504079_0 E1-E2 ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 533.0
HKD1_k127_3504079_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 391.0
HKD1_k127_3504079_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000005103 195.0
HKD1_k127_3504079_5 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000004567 147.0
HKD1_k127_3504079_6 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000001155 109.0
HKD1_k127_3504079_7 Domain of unknown function (DUF1508) K09946 - - 0.0000000000000000014 95.0
HKD1_k127_3504079_9 Domain of unknown function (DUF1508) K09946 - - 0.000000000001494 77.0
HKD1_k127_3508734_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 5.921e-206 651.0
HKD1_k127_3508734_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 440.0
HKD1_k127_3508734_3 Rhodanese Homology Domain - - - 0.000000000000000000000000105 109.0
HKD1_k127_3508734_4 Beta-L-arabinofuranosidase, GH127 - - - 0.0005405 52.0
HKD1_k127_3508734_5 Phosphoesterase family K01114 - 3.1.4.3 0.0006609 49.0
HKD1_k127_3513127_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 451.0
HKD1_k127_3513127_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K07533 - 5.2.1.8 0.0000000000000000002541 104.0
HKD1_k127_3514150_0 metallopeptidase activity K01179 - 3.2.1.4 6.721e-226 717.0
HKD1_k127_3514150_1 DNA-binding response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 503.0
HKD1_k127_3514150_11 phosphorelay signal transduction system - - - 0.0000000000004161 74.0
HKD1_k127_3514150_12 WGR domain protein - - - 0.00000000003326 76.0
HKD1_k127_3514150_13 diguanylate cyclase - - - 0.000003133 55.0
HKD1_k127_3514150_14 Calcium-binding EGF domain - - - 0.000006631 58.0
HKD1_k127_3514150_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 362.0
HKD1_k127_3514150_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
HKD1_k127_3514150_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005479 287.0
HKD1_k127_3514150_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000006016 186.0
HKD1_k127_3514150_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001056 169.0
HKD1_k127_3514150_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000002413 137.0
HKD1_k127_3514150_8 Protein of unknown function (DUF4241) - - - 0.000000000000000000000000000001354 138.0
HKD1_k127_3514150_9 OmpA family K03286 - - 0.00000000000000000003586 106.0
HKD1_k127_3516202_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002913 237.0
HKD1_k127_3516202_1 Zinc finger, swim domain protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000005493 239.0
HKD1_k127_3516202_2 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.00000000000000000000000000002779 133.0
HKD1_k127_3524374_0 ABC-type multidrug transport system ATPase component K13926 - - 0.0 1373.0
HKD1_k127_3524374_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 563.0
HKD1_k127_3524374_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 511.0
HKD1_k127_3524374_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 384.0
HKD1_k127_3524374_4 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 374.0
HKD1_k127_3524374_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000003516 181.0
HKD1_k127_3524374_6 exo-alpha-(2->6)-sialidase activity - - - 0.000000008299 68.0
HKD1_k127_3524374_7 transcriptional regulator K06075 - - 0.00000003609 62.0
HKD1_k127_3528288_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 563.0
HKD1_k127_3528288_1 - - - - 0.00000000000000000000000000000001258 133.0
HKD1_k127_3531192_0 Tetratricopeptide repeat - - - 0.0 1202.0
HKD1_k127_3531192_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 413.0
HKD1_k127_3531192_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 414.0
HKD1_k127_3531192_3 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 392.0
HKD1_k127_3531192_5 Response regulator receiver domain - - - 0.0002006 48.0
HKD1_k127_3545183_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 396.0
HKD1_k127_3545183_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 363.0
HKD1_k127_3545183_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000004526 56.0
HKD1_k127_3545183_2 ATPase domain of DNA mismatch repair MUTS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
HKD1_k127_3545183_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 338.0
HKD1_k127_3545183_5 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002444 259.0
HKD1_k127_3545183_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000004861 243.0
HKD1_k127_3545183_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000002157 198.0
HKD1_k127_3545183_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000007465 176.0
HKD1_k127_3545183_9 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000008463 129.0
HKD1_k127_3563519_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.239e-210 665.0
HKD1_k127_3563519_1 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 451.0
HKD1_k127_3563519_2 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000000007082 177.0
HKD1_k127_3563519_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000099 173.0
HKD1_k127_3563519_4 DNA-binding regulatory protein K03088 - - 0.0000000000000000000000000000000000000002417 159.0
HKD1_k127_3565153_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 505.0
HKD1_k127_3565153_1 Putative restriction endonuclease - - - 0.00000000000000000000001759 107.0
HKD1_k127_3566199_0 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 546.0
HKD1_k127_3566199_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 539.0
HKD1_k127_3566199_11 Protein of unknown function (DUF4230) - - - 0.0000000000000001223 88.0
HKD1_k127_3566199_12 Calcium-binding EGF domain - - - 0.00001946 57.0
HKD1_k127_3566199_13 Amidohydrolase family - - - 0.00005596 57.0
HKD1_k127_3566199_2 IrrE N-terminal-like domain K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 465.0
HKD1_k127_3566199_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001346 293.0
HKD1_k127_3566199_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663,K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
HKD1_k127_3566199_5 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000006 225.0
HKD1_k127_3566199_6 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000007288 193.0
HKD1_k127_3566199_7 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000004385 203.0
HKD1_k127_3566199_8 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000000000007141 168.0
HKD1_k127_3570624_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.887e-279 880.0
HKD1_k127_3570624_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 336.0
HKD1_k127_3570624_10 ThiS family - - - 0.00003453 46.0
HKD1_k127_3570624_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001823 274.0
HKD1_k127_3570624_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004206 265.0
HKD1_k127_3570624_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000009376 235.0
HKD1_k127_3570624_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000024 171.0
HKD1_k127_3570624_6 - - - - 0.000000000000000000000000000000000002713 144.0
HKD1_k127_3570624_8 Protein of unknown function DUF86 - - - 0.0000000656 61.0
HKD1_k127_3570624_9 Nucleotidyltransferase domain K07076 - - 0.0000005857 58.0
HKD1_k127_3571150_0 PHP domain protein - - - 2.768e-216 707.0
HKD1_k127_3571150_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 378.0
HKD1_k127_3571150_2 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 347.0
HKD1_k127_3571150_3 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001003 201.0
HKD1_k127_3571150_4 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000006442 177.0
HKD1_k127_3571150_5 Family membership - - - 0.0000000000004297 78.0
HKD1_k127_3571150_6 Role in flagellar biosynthesis K02420 - - 0.000001497 60.0
HKD1_k127_3572912_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 454.0
HKD1_k127_3572912_1 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 312.0
HKD1_k127_3572912_2 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000001336 246.0
HKD1_k127_3572912_4 membrane K06377 - - 0.000000000000000000000000000000001245 141.0
HKD1_k127_3572912_5 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000001573 139.0
HKD1_k127_3572912_6 NUDIX domain - - - 0.00000000002354 65.0
HKD1_k127_3572912_7 YndJ-like protein - - - 0.000008926 51.0
HKD1_k127_3573619_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 334.0
HKD1_k127_3573619_1 Squalene/phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000002468 209.0
HKD1_k127_3573619_2 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000000000000000000000000000005188 179.0
HKD1_k127_3573619_3 - - - - 0.000000000000000000000003313 117.0
HKD1_k127_3573619_4 metallo-beta-lactamase - - - 0.000000000000000000004009 98.0
HKD1_k127_3577413_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 433.0
HKD1_k127_3577413_2 - - - - 0.00000000000000002102 97.0
HKD1_k127_3577413_3 Anti-sigma factor K07167,K12132,K20148 - 1.13.11.50,2.7.11.1 0.0000000000002651 72.0
HKD1_k127_3615401_0 UPF0313 protein - - - 1.208e-294 917.0
HKD1_k127_3615401_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.734e-197 633.0
HKD1_k127_3615401_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000009464 147.0
HKD1_k127_3615401_3 Domain of unknown function (DUF4166) - - - 0.0000000000000000003652 93.0
HKD1_k127_3620569_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 554.0
HKD1_k127_3620569_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 441.0
HKD1_k127_3620569_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
HKD1_k127_3620569_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000002309 213.0
HKD1_k127_3620569_4 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000003045 192.0
HKD1_k127_3620569_5 Penicillin binding protein transpeptidase domain K17838 - 3.5.2.6 0.00000000000000000000000000000000000000000000000005016 193.0
HKD1_k127_3620569_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000231 136.0
HKD1_k127_3620569_7 Type II/IV secretion system protein K02283 - - 0.0000002232 55.0
HKD1_k127_3635858_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 455.0
HKD1_k127_3635858_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 445.0
HKD1_k127_3635858_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000003301 113.0
HKD1_k127_3635858_11 - - - - 0.000000000000000000000003131 117.0
HKD1_k127_3635858_12 YCII-related domain - - - 0.000000000000000001199 93.0
HKD1_k127_3635858_13 Ankyrin repeat - - - 0.000000000000000004764 100.0
HKD1_k127_3635858_14 Membrane - - - 0.000000000000000097 93.0
HKD1_k127_3635858_15 YCII-related domain - - - 0.0000000000000002856 86.0
HKD1_k127_3635858_16 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000005435 63.0
HKD1_k127_3635858_18 Flavodoxin-like fold K00355 - 1.6.5.2 0.0004455 46.0
HKD1_k127_3635858_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 343.0
HKD1_k127_3635858_3 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 329.0
HKD1_k127_3635858_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000005791 228.0
HKD1_k127_3635858_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000007648 194.0
HKD1_k127_3635858_6 PFAM phosphoesterase K01114 - 3.1.4.3 0.0000000000000000000000000000000000005081 149.0
HKD1_k127_3635858_7 Belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000003986 141.0
HKD1_k127_3635858_8 Amidohydrolase family - - - 0.0000000000000000000000000000000475 141.0
HKD1_k127_3635858_9 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000367 124.0
HKD1_k127_3638497_0 PFAM carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
HKD1_k127_3638497_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 376.0
HKD1_k127_3638497_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 277.0
HKD1_k127_3638497_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000134 190.0
HKD1_k127_3638497_4 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000003597 130.0
HKD1_k127_3638497_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000001566 122.0
HKD1_k127_3638497_6 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.00000000000000009589 90.0
HKD1_k127_3638497_7 amine dehydrogenase activity - - - 0.0000000000000002644 93.0
HKD1_k127_3638497_8 - - - - 0.000000000000002736 90.0
HKD1_k127_3638497_9 amine dehydrogenase activity - - - 0.00000008523 64.0
HKD1_k127_3643690_0 Serine Threonine protein kinase K12132 - 2.7.11.1 8.111e-320 1007.0
HKD1_k127_3643690_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 533.0
HKD1_k127_3643690_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 369.0
HKD1_k127_3643690_3 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 326.0
HKD1_k127_3643690_4 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 334.0
HKD1_k127_3674854_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 511.0
HKD1_k127_3674854_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 407.0
HKD1_k127_3674854_2 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 405.0
HKD1_k127_3674854_3 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000007187 216.0
HKD1_k127_3674854_4 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000008998 201.0
HKD1_k127_3674854_7 - - - - 0.0000004565 60.0
HKD1_k127_3686332_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000434 304.0
HKD1_k127_3686332_1 protein trimerization K06894,K07114 - - 0.000000001235 61.0
HKD1_k127_369464_0 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 400.0
HKD1_k127_369464_1 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000876 272.0
HKD1_k127_369464_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000005458 196.0
HKD1_k127_3698138_0 Cell division protein FtsI penicillin-binding protein 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 302.0
HKD1_k127_3698138_1 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 311.0
HKD1_k127_3698138_2 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 262.0
HKD1_k127_3698138_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000009835 140.0
HKD1_k127_3717894_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 1.172e-212 668.0
HKD1_k127_3717894_1 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 399.0
HKD1_k127_3717894_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
HKD1_k127_3717894_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000002659 157.0
HKD1_k127_3717894_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000001417 129.0
HKD1_k127_3724737_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 395.0
HKD1_k127_3724737_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
HKD1_k127_3724737_2 - - - - 0.00000000000000000005114 90.0
HKD1_k127_3729689_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 313.0
HKD1_k127_3729689_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
HKD1_k127_3729689_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000008749 221.0
HKD1_k127_3729689_3 Universal stress protein family K06149 - - 0.0000000000000001873 92.0
HKD1_k127_3751100_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 374.0
HKD1_k127_3751100_1 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001041 251.0
HKD1_k127_3751100_2 FR47-like protein - - - 0.000000000002005 74.0
HKD1_k127_3754097_0 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000009761 227.0
HKD1_k127_3754097_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000001512 181.0
HKD1_k127_3769542_0 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 331.0
HKD1_k127_3769542_1 Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000007434 250.0
HKD1_k127_3769542_3 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000003472 93.0
HKD1_k127_3777736_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 5.679e-231 738.0
HKD1_k127_3777736_1 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 389.0
HKD1_k127_3777736_2 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 366.0
HKD1_k127_3777736_3 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 317.0
HKD1_k127_3786964_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 4.748e-221 726.0
HKD1_k127_3786964_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 354.0
HKD1_k127_3786964_2 Radical SAM superfamily K06139 - - 0.000000000000000000000000000000001684 135.0
HKD1_k127_3786964_3 bacterial-type flagellum organization - - - 0.0000000000000000000000001002 118.0
HKD1_k127_3786964_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000009106 69.0
HKD1_k127_378836_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 454.0
HKD1_k127_378836_1 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 344.0
HKD1_k127_3789223_0 type IV pilus secretin PilQ K02666 - - 1.526e-274 863.0
HKD1_k127_3789223_1 MMPL family K07003 - - 1.408e-211 693.0
HKD1_k127_3789223_10 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000001873 165.0
HKD1_k127_3789223_11 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000001009 164.0
HKD1_k127_3789223_13 WD-40 repeat - - - 0.000000000000000000376 101.0
HKD1_k127_3789223_16 Stigma-specific protein, Stig1 - - - 0.0000002655 59.0
HKD1_k127_3789223_2 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 422.0
HKD1_k127_3789223_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 333.0
HKD1_k127_3789223_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 292.0
HKD1_k127_3789223_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000004197 250.0
HKD1_k127_3789223_7 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000001333 221.0
HKD1_k127_3789223_8 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000003444 229.0
HKD1_k127_3789223_9 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000001649 189.0
HKD1_k127_3793115_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 333.0
HKD1_k127_3793115_1 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001914 293.0
HKD1_k127_3793115_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000000001309 153.0
HKD1_k127_3793518_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 272.0
HKD1_k127_3793518_1 alpha beta - - - 0.00000000000000000000000000000000000868 153.0
HKD1_k127_3794880_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 434.0
HKD1_k127_3794880_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000006427 265.0
HKD1_k127_3794880_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000002535 193.0
HKD1_k127_3794880_3 ABC transporter transmembrane region K16013 - - 0.0000000000000000000000004445 112.0
HKD1_k127_3794880_4 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000193 94.0
HKD1_k127_3799843_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 387.0
HKD1_k127_3799843_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000009755 265.0
HKD1_k127_3799843_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000006326 128.0
HKD1_k127_3799843_3 COG0433 Predicted ATPase - - - 0.0000000000005983 72.0
HKD1_k127_3803842_0 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000008728 117.0
HKD1_k127_3803842_1 peptidyl-tyrosine sulfation - - - 0.000000000000114 84.0
HKD1_k127_3803842_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00001714 57.0
HKD1_k127_3803842_3 FHA domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00005211 56.0
HKD1_k127_380504_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.878e-284 878.0
HKD1_k127_380504_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 2.729e-227 724.0
HKD1_k127_380504_10 - - - - 0.000000000000000000000000002618 124.0
HKD1_k127_380504_11 iron ion homeostasis K04758 - - 0.000009884 51.0
HKD1_k127_380504_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.254e-197 634.0
HKD1_k127_380504_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.183e-195 624.0
HKD1_k127_380504_4 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 559.0
HKD1_k127_380504_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000002801 229.0
HKD1_k127_380504_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000001834 163.0
HKD1_k127_380504_8 - - - - 0.0000000000000000000000000000000003215 140.0
HKD1_k127_3808098_0 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 415.0
HKD1_k127_3808098_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000001066 184.0
HKD1_k127_3812771_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 597.0
HKD1_k127_3812771_1 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 483.0
HKD1_k127_3812771_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 399.0
HKD1_k127_3812771_3 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 397.0
HKD1_k127_3812771_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 323.0
HKD1_k127_3812771_5 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 308.0
HKD1_k127_3812771_6 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000003838 86.0
HKD1_k127_3821443_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000001534 138.0
HKD1_k127_3821443_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000009156 112.0
HKD1_k127_3821443_3 - - - - 0.000000000000735 78.0
HKD1_k127_3821443_4 Calcineurin-like phosphoesterase - - - 0.0001019 55.0
HKD1_k127_3821697_0 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000002934 216.0
HKD1_k127_3821697_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000001663 184.0
HKD1_k127_3821697_2 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000004087 168.0
HKD1_k127_3821697_3 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase. Source PGD - - - 0.000000000000000000000008476 105.0
HKD1_k127_3822045_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1060.0
HKD1_k127_3822045_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 544.0
HKD1_k127_3822045_2 protein trimerization - - - 0.000000000000000000000000000000000000000000000000000000004121 209.0
HKD1_k127_3824677_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 584.0
HKD1_k127_3824677_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000006938 243.0
HKD1_k127_3824677_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000044 199.0
HKD1_k127_3824677_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000003029 183.0
HKD1_k127_3824677_5 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000003416 188.0
HKD1_k127_3824677_6 Glyoxalase-like domain - - - 0.000000000000000000000000000000000004264 150.0
HKD1_k127_3824677_8 pyrroloquinoline quinone binding - - - 0.0000000000000001124 92.0
HKD1_k127_3824677_9 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000001113 63.0
HKD1_k127_3845207_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 558.0
HKD1_k127_3845207_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 474.0
HKD1_k127_3845207_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000001582 252.0
HKD1_k127_3845207_3 - - - - 0.00000000000000000000000000000000000000000000175 168.0
HKD1_k127_3845207_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000009477 107.0
HKD1_k127_3845207_6 Transcriptional regulator - - - 0.0005938 46.0
HKD1_k127_384611_0 MCM2/3/5 family K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 479.0
HKD1_k127_384611_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 352.0
HKD1_k127_384611_2 - - - - 0.00000000000000000000000000000000000000000000518 172.0
HKD1_k127_384611_3 nuclear chromosome segregation - - - 0.00000000003276 72.0
HKD1_k127_3850707_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000006117 245.0
HKD1_k127_3850707_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000001192 127.0
HKD1_k127_385873_0 Glycosyl transferase family 21 - - - 1.155e-204 647.0
HKD1_k127_385873_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 642.0
HKD1_k127_385873_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 607.0
HKD1_k127_385873_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 310.0
HKD1_k127_385873_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000003372 157.0
HKD1_k127_385873_5 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000009908 152.0
HKD1_k127_385873_6 Multiple ankyrin repeats single kh domain - - - 0.00000000000002718 83.0
HKD1_k127_385873_7 protein trimerization - - - 0.000001428 61.0
HKD1_k127_3866074_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 421.0
HKD1_k127_3866074_1 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 396.0
HKD1_k127_3866074_3 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000004081 122.0
HKD1_k127_3866074_4 S23 ribosomal protein - - - 0.00000000000000000000000001412 113.0
HKD1_k127_3866074_6 Aminotransferase, class V - - - 0.00000003936 61.0
HKD1_k127_3866074_7 - - - - 0.00007137 51.0
HKD1_k127_3917796_0 Family membership - - - 1.248e-269 861.0
HKD1_k127_3917796_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000001253 178.0
HKD1_k127_3919116_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000004029 171.0
HKD1_k127_3919116_1 AMP binding - GO:0008150,GO:0040007 - 0.00000000000005434 82.0
HKD1_k127_3919116_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000002983 61.0
HKD1_k127_3919116_3 Prohibitin K17080 GO:0000001,GO:0001302,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006457,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0007568,GO:0007569,GO:0008150,GO:0009653,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0019222,GO:0019866,GO:0030162,GO:0031090,GO:0031323,GO:0031324,GO:0031966,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032502,GO:0032989,GO:0032990,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045861,GO:0048308,GO:0048311,GO:0048519,GO:0048523,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051246,GO:0051248,GO:0051640,GO:0051641,GO:0051646,GO:0060255,GO:0061024,GO:0065007,GO:0070584,GO:0071840,GO:0080090 - 0.00009113 54.0
HKD1_k127_393747_0 Family membership - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 471.0
HKD1_k127_393747_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 426.0
HKD1_k127_393747_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000156 143.0
HKD1_k127_393747_11 membrane organization - - - 0.00000000000000000000000000000000327 145.0
HKD1_k127_393747_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000005979 123.0
HKD1_k127_393747_15 Domain of unknown function (DUF2383) - - - 0.00000000000002263 81.0
HKD1_k127_393747_16 LysM domain - - - 0.0000000000002058 83.0
HKD1_k127_393747_17 ATP:ADP antiporter activity K03301 - - 0.000003604 59.0
HKD1_k127_393747_18 DoxX K15977 - - 0.0007833 48.0
HKD1_k127_393747_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 338.0
HKD1_k127_393747_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 330.0
HKD1_k127_393747_4 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 315.0
HKD1_k127_393747_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001379 310.0
HKD1_k127_393747_6 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000107 279.0
HKD1_k127_393747_7 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000001357 196.0
HKD1_k127_393747_8 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000003575 151.0
HKD1_k127_393747_9 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000001808 154.0
HKD1_k127_3941993_0 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000003432 202.0
HKD1_k127_3941993_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000001067 175.0
HKD1_k127_3941993_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000002589 159.0
HKD1_k127_3941993_3 amino acid - - - 0.0000000000000000000000000000000004233 134.0
HKD1_k127_3941993_4 Tetratricopeptide repeat - - - 0.0007126 53.0
HKD1_k127_3967854_0 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 299.0
HKD1_k127_3967854_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001293 225.0
HKD1_k127_3975073_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.04e-205 658.0
HKD1_k127_3975073_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 424.0
HKD1_k127_3975073_2 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 346.0
HKD1_k127_3975073_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007092 241.0
HKD1_k127_3975073_4 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000194 211.0
HKD1_k127_3975073_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000001118 103.0
HKD1_k127_3975073_6 - - - - 0.000000001932 70.0
HKD1_k127_3988472_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 4.796e-234 748.0
HKD1_k127_3988472_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 525.0
HKD1_k127_3988472_10 - - - - 0.0000000000000000121 83.0
HKD1_k127_3988472_11 - - - - 0.0000000000001105 75.0
HKD1_k127_3988472_15 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0004146 52.0
HKD1_k127_3988472_2 deoxyhypusine monooxygenase activity K01256,K02563,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 388.0
HKD1_k127_3988472_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 353.0
HKD1_k127_3988472_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003248 283.0
HKD1_k127_3988472_5 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005853 229.0
HKD1_k127_3988472_6 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000007124 172.0
HKD1_k127_3988472_7 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000004782 173.0
HKD1_k127_3988472_9 2-dehydropantoate 2-reductase activity K00077,K04940 - 1.1.1.169,1.5.1.28 0.0000000000000000000001391 101.0
HKD1_k127_3991887_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 495.0
HKD1_k127_3991887_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 378.0
HKD1_k127_3991887_12 Polysaccharide biosynthesis/export protein - - - 0.00000009461 61.0
HKD1_k127_3991887_2 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 363.0
HKD1_k127_3991887_3 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
HKD1_k127_3991887_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008423 284.0
HKD1_k127_3991887_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001209 263.0
HKD1_k127_3991887_6 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002251 231.0
HKD1_k127_3991887_7 - - - - 0.00000000000000000000000000000000000000000001409 169.0
HKD1_k127_3991887_8 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000002531 168.0
HKD1_k127_399510_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 599.0
HKD1_k127_399510_1 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 315.0
HKD1_k127_399510_10 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000004615 115.0
HKD1_k127_399510_12 Family membership - - - 0.0000000000000006551 82.0
HKD1_k127_399510_13 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000001117 81.0
HKD1_k127_399510_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002202 301.0
HKD1_k127_399510_3 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002086 270.0
HKD1_k127_399510_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000002535 184.0
HKD1_k127_399510_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000001126 152.0
HKD1_k127_399510_6 anti-sigma regulatory factor - - - 0.00000000000000000000000000000000001066 152.0
HKD1_k127_399510_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K17752 - 2.7.11.1 0.0000000000000000000000000000001045 130.0
HKD1_k127_399510_8 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.000000000000000000000000001695 120.0
HKD1_k127_399510_9 Universal stress protein - - - 0.000000000000000000000000012 116.0
HKD1_k127_4004465_0 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000009011 188.0
HKD1_k127_4004465_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001766 132.0
HKD1_k127_4004465_2 PAP2 superfamily - - - 0.0000001234 56.0
HKD1_k127_4004576_0 Domain of unknown function (DUF1998) K06877 - - 6.194e-306 955.0
HKD1_k127_4004576_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 413.0
HKD1_k127_4004576_2 Type II/IV secretion system protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 402.0
HKD1_k127_4004576_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 392.0
HKD1_k127_4004576_4 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HKD1_k127_4004576_5 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001265 297.0
HKD1_k127_4004576_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000037 192.0
HKD1_k127_4004576_7 IgGFc binding protein - - - 0.000000000000000000000008476 105.0
HKD1_k127_4012777_0 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000003573 161.0
HKD1_k127_4012777_1 TonB dependent receptor - - - 0.00000000000000000000005294 108.0
HKD1_k127_4012777_3 - - - - 0.00000000001455 78.0
HKD1_k127_401279_0 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 502.0
HKD1_k127_401279_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 323.0
HKD1_k127_4015089_0 ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 503.0
HKD1_k127_4015089_1 PFAM DNA primase small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 516.0
HKD1_k127_4015089_2 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000004833 193.0
HKD1_k127_4015089_3 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000109 181.0
HKD1_k127_4015089_4 aminopeptidase - - - 0.0000000000000000008651 98.0
HKD1_k127_4034577_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 380.0
HKD1_k127_4034577_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 364.0
HKD1_k127_4034577_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 312.0
HKD1_k127_4034577_3 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 308.0
HKD1_k127_4034577_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
HKD1_k127_4034577_5 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000372 193.0
HKD1_k127_4034577_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002237 173.0
HKD1_k127_4034577_8 Methyltransferase domain - - - 0.000000000000000000009978 101.0
HKD1_k127_4037758_0 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 369.0
HKD1_k127_4037758_1 Thiol disulfide Interchange Protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 276.0
HKD1_k127_4037758_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
HKD1_k127_4037758_3 Membrane K04088,K14393 - - 0.00000000000000000000000000000000000000000000000000000000000002382 238.0
HKD1_k127_4037758_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001142 158.0
HKD1_k127_4037758_5 - - - - 0.00000000000000000000008955 111.0
HKD1_k127_4037758_6 ECF sigma factor - - - 0.000000000000155 78.0
HKD1_k127_4037758_8 - - - - 0.000000099 62.0
HKD1_k127_4040766_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 382.0
HKD1_k127_4040766_1 - - - - 0.0000000000000000000000000009748 128.0
HKD1_k127_4040766_2 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000000003184 108.0
HKD1_k127_4040766_3 - - - - 0.00000004824 56.0
HKD1_k127_4054976_0 Protein of unknown function (DUF2786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 375.0
HKD1_k127_4054976_1 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000001983 204.0
HKD1_k127_4054976_3 Methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000005096 131.0
HKD1_k127_4054976_4 protein conserved in cyanobacteria - - - 0.0000000000000000009233 89.0
HKD1_k127_4054976_5 GABA-A receptor activity K05181 GO:0001505,GO:0002118,GO:0002121,GO:0003674,GO:0004888,GO:0004890,GO:0005215,GO:0005216,GO:0005230,GO:0005253,GO:0005254,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006821,GO:0006836,GO:0007154,GO:0007165,GO:0007186,GO:0007214,GO:0007610,GO:0007626,GO:0007635,GO:0008021,GO:0008150,GO:0008503,GO:0008509,GO:0009605,GO:0009612,GO:0009628,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0012506,GO:0015075,GO:0015103,GO:0015108,GO:0015267,GO:0015276,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0016917,GO:0022803,GO:0022824,GO:0022834,GO:0022835,GO:0022836,GO:0022838,GO:0022839,GO:0022851,GO:0022857,GO:0023051,GO:0023052,GO:0023057,GO:0030133,GO:0030285,GO:0030424,GO:0030425,GO:0030431,GO:0030594,GO:0030658,GO:0030659,GO:0030672,GO:0031090,GO:0031224,GO:0031252,GO:0031253,GO:0031256,GO:0031300,GO:0031301,GO:0031410,GO:0031594,GO:0031644,GO:0031982,GO:0032501,GO:0032589,GO:0032809,GO:0034220,GO:0036477,GO:0038023,GO:0040012,GO:0042048,GO:0042221,GO:0042493,GO:0042749,GO:0042752,GO:0042995,GO:0043005,GO:0043025,GO:0043058,GO:0043226,GO:0043227,GO:0043229,GO:0044057,GO:0044297,GO:0044298,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045211,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050795,GO:0050804,GO:0050805,GO:0050896,GO:0051179,GO:0051234,GO:0051239,GO:0051704,GO:0051705,GO:0051716,GO:0055085,GO:0060089,GO:0065007,GO:0065008,GO:0070382,GO:0071944,GO:0090328,GO:0097060,GO:0097447,GO:0097458,GO:0097708,GO:0098563,GO:0098588,GO:0098590,GO:0098656,GO:0098660,GO:0098661,GO:0098793,GO:0098794,GO:0098805,GO:0099095,GO:0099177,GO:0099501,GO:0099503,GO:0120025,GO:0120038,GO:1902476 - 0.00009445 54.0
HKD1_k127_4054976_6 Neurotransmitter-gated ion-channel ligand binding domain - - - 0.0003627 47.0
HKD1_k127_4055677_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
HKD1_k127_4055677_1 - - - - 0.000000002889 69.0
HKD1_k127_4062511_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.268e-204 653.0
HKD1_k127_4062511_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000178 239.0
HKD1_k127_4062511_2 OmpA MotB domain protein - - - 0.00001766 55.0
HKD1_k127_4066688_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 5.826e-245 779.0
HKD1_k127_4066688_1 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 446.0
HKD1_k127_4066688_2 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007964 292.0
HKD1_k127_4071006_0 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 317.0
HKD1_k127_4071006_1 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004366 247.0
HKD1_k127_4071006_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000006988 157.0
HKD1_k127_4071006_4 - - - - 0.0000000000000000000000000002331 131.0
HKD1_k127_4071006_5 Thioesterase superfamily K07107 - - 0.000000000000000000000000173 110.0
HKD1_k127_4071006_6 FHA domain - - - 0.0000000000000000000004873 107.0
HKD1_k127_4071006_8 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000002547 71.0
HKD1_k127_407538_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 590.0
HKD1_k127_407538_1 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 473.0
HKD1_k127_407538_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
HKD1_k127_407538_3 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 329.0
HKD1_k127_407538_6 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000001697 166.0
HKD1_k127_407538_7 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000002632 152.0
HKD1_k127_407538_8 Belongs to the ompA family K03640 - - 0.0000000000000000000000000002174 121.0
HKD1_k127_4078552_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 322.0
HKD1_k127_4078552_1 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002449 273.0
HKD1_k127_4078552_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000002364 86.0
HKD1_k127_4078552_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000002025 65.0
HKD1_k127_4088517_0 Tetratricopeptide repeat - - - 7.47e-305 969.0
HKD1_k127_4088517_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 371.0
HKD1_k127_4088517_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000008662 190.0
HKD1_k127_4091437_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 318.0
HKD1_k127_4091437_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002797 285.0
HKD1_k127_4091437_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003619 298.0
HKD1_k127_4091437_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000001745 229.0
HKD1_k127_4091437_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000002625 117.0
HKD1_k127_410016_0 Alpha-amylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 421.0
HKD1_k127_410016_1 Signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 275.0
HKD1_k127_4110490_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 555.0
HKD1_k127_4110490_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 413.0
HKD1_k127_4110490_2 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000006149 213.0
HKD1_k127_4114458_0 PFAM Glutamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 269.0
HKD1_k127_4114458_1 Bestrophin, RFP-TM, chloride channel K08994 - - 0.0000000000000000000000000000000000000000000000000000000000351 215.0
HKD1_k127_4114458_2 OsmC-like protein - - - 0.00000000000000000000000001808 125.0
HKD1_k127_4114458_3 - - - - 0.00000000004025 69.0
HKD1_k127_4121925_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 295.0
HKD1_k127_4121925_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
HKD1_k127_4121925_2 - - - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD1_k127_4121925_4 GGDEF domain - - - 0.000000000000002815 79.0
HKD1_k127_4123749_0 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 493.0
HKD1_k127_4123749_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 409.0
HKD1_k127_4123749_2 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000001026 229.0
HKD1_k127_4123749_3 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000001769 181.0
HKD1_k127_4123749_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000356 124.0
HKD1_k127_4145764_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 595.0
HKD1_k127_4162597_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 441.0
HKD1_k127_4162597_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 263.0
HKD1_k127_4162597_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000009992 105.0
HKD1_k127_4162597_3 - - - - 0.000000000000001297 90.0
HKD1_k127_4171014_0 COG NOG14600 non supervised orthologous group - - - 0.00000000000000008779 79.0
HKD1_k127_4171014_1 Unextendable partial coding region - - - 0.000000001757 61.0
HKD1_k127_4171014_2 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000009096 65.0
HKD1_k127_4171014_3 CAAX protease self-immunity K07052 - - 0.000004066 54.0
HKD1_k127_4183263_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000007737 184.0
HKD1_k127_4183263_1 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000002187 159.0
HKD1_k127_4183263_2 NADPH quinone reductase - - - 0.00001661 47.0
HKD1_k127_4183263_3 - - - - 0.0006435 52.0
HKD1_k127_4193884_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1524.0
HKD1_k127_4193884_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 492.0
HKD1_k127_4193884_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000008464 58.0
HKD1_k127_4209081_0 - - - - 0.00000000000000000000000003626 123.0
HKD1_k127_4209081_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000407 106.0
HKD1_k127_4209081_2 Copper binding proteins, plastocyanin/azurin family - GO:0008150,GO:0008152,GO:0055114 - 0.000000000000000005384 93.0
HKD1_k127_4209081_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000002181 81.0
HKD1_k127_4215408_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 500.0
HKD1_k127_4215408_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 437.0
HKD1_k127_4215408_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001836 279.0
HKD1_k127_4215408_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000188 106.0
HKD1_k127_4215689_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 577.0
HKD1_k127_4215689_1 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 342.0
HKD1_k127_4215689_3 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000002066 169.0
HKD1_k127_4215689_4 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000005002 150.0
HKD1_k127_4215689_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000008028 154.0
HKD1_k127_4215689_6 lipopolysaccharide transmembrane transporter activity K06178,K07058 - 5.4.99.22 0.00000000000000000000000000000000007932 147.0
HKD1_k127_4215689_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000001373 95.0
HKD1_k127_421944_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 5.216e-257 807.0
HKD1_k127_421944_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.194e-209 664.0
HKD1_k127_421944_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000009675 218.0
HKD1_k127_421944_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000001324 218.0
HKD1_k127_421944_4 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000000000004254 197.0
HKD1_k127_421944_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000002571 153.0
HKD1_k127_421944_6 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000002123 146.0
HKD1_k127_421944_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000002503 115.0
HKD1_k127_421944_8 Thioesterase superfamily - - - 0.000000000000000000003545 98.0
HKD1_k127_421944_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0000691 53.0
HKD1_k127_4222030_0 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
HKD1_k127_4222030_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 319.0
HKD1_k127_4222030_2 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000001955 225.0
HKD1_k127_4222030_3 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00000000000000000000000000000000000000000000000000000006986 205.0
HKD1_k127_4222030_4 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000004895 188.0
HKD1_k127_4222030_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001598 178.0
HKD1_k127_4222030_6 Dynamin family - - - 0.000000000000000002529 89.0
HKD1_k127_4224099_0 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 441.0
HKD1_k127_4224099_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 357.0
HKD1_k127_4224099_2 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 339.0
HKD1_k127_4224099_3 Binding-protein-dependent transport system inner membrane component K05815 - - 0.000000000000000000000000000000000000000000000003261 189.0
HKD1_k127_4224099_4 - - - - 0.0000000000000000000001636 111.0
HKD1_k127_4224099_5 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000009903 86.0
HKD1_k127_4232123_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 263.0
HKD1_k127_4232123_2 - - - - 0.00000000000000000000003016 112.0
HKD1_k127_4232123_3 Cytochrome c-type biogenesis protein K02198 - - 0.000000000000000000006184 102.0
HKD1_k127_4235522_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 412.0
HKD1_k127_4235522_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000611 170.0
HKD1_k127_4235522_2 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000001708 106.0
HKD1_k127_4240825_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 334.0
HKD1_k127_4240825_1 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 334.0
HKD1_k127_4240825_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000001415 196.0
HKD1_k127_4246423_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 528.0
HKD1_k127_4246423_1 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 359.0
HKD1_k127_4246423_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000518 169.0
HKD1_k127_4246423_3 peptidase - - - 0.000000000000000000000000001227 125.0
HKD1_k127_4246423_4 Transcription factor zinc-finger - - - 0.000000000001144 77.0
HKD1_k127_4246423_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000006864 51.0
HKD1_k127_4246423_6 amine dehydrogenase activity - - - 0.000009482 57.0
HKD1_k127_4250608_1 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000003073 77.0
HKD1_k127_4252905_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 502.0
HKD1_k127_4252905_1 - - - - 0.000000000000000000000000000000000000003576 161.0
HKD1_k127_4252905_3 protein secretion K03116 - - 0.0000000007833 66.0
HKD1_k127_4252905_4 protein secretion K03116 - - 0.00000007626 64.0
HKD1_k127_425449_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002341 278.0
HKD1_k127_425449_1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003116 274.0
HKD1_k127_425449_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000006412 132.0
HKD1_k127_425449_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000006976 79.0
HKD1_k127_425449_4 - - - - 0.000000000000002842 89.0
HKD1_k127_4257582_0 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 4.286e-231 727.0
HKD1_k127_4257582_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 542.0
HKD1_k127_4257582_2 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 450.0
HKD1_k127_4257582_3 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 346.0
HKD1_k127_4257582_4 Glycoside-hydrolase family GH114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
HKD1_k127_4257582_5 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000008189 214.0
HKD1_k127_4257582_6 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.0000000000000000000000000000000000000000000004022 186.0
HKD1_k127_4257582_7 endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000004023 174.0
HKD1_k127_4257582_8 - - - - 0.000000000000000000000000009228 114.0
HKD1_k127_4257582_9 SnoaL-like domain - - - 0.000000000000000000000001077 107.0
HKD1_k127_425838_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 440.0
HKD1_k127_425838_1 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 376.0
HKD1_k127_425838_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 348.0
HKD1_k127_425838_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 342.0
HKD1_k127_425838_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000514 248.0
HKD1_k127_425838_6 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000005376 223.0
HKD1_k127_425838_7 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000003418 162.0
HKD1_k127_425838_8 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000002834 147.0
HKD1_k127_425838_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000001632 97.0
HKD1_k127_4267671_0 - - - - 0.00000000000000000000000000004671 128.0
HKD1_k127_4267671_1 Cytochrome c - - - 0.00000000000000000003784 95.0
HKD1_k127_4267671_2 Kazal type serine protease inhibitors - - - 0.0000000000000004976 89.0
HKD1_k127_4267815_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 513.0
HKD1_k127_4267815_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 373.0
HKD1_k127_4267815_2 Domain of unknown function (DUF4382) - - - 0.000008518 54.0
HKD1_k127_4296471_0 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 401.0
HKD1_k127_4296471_3 translation initiation factor activity - - - 0.0000000000000000000000000005645 118.0
HKD1_k127_4296471_4 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000001509 117.0
HKD1_k127_4328460_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001897 242.0
HKD1_k127_4328460_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000008471 158.0
HKD1_k127_4328460_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000006262 58.0
HKD1_k127_4328460_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00002821 55.0
HKD1_k127_4328829_0 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 317.0
HKD1_k127_4328829_1 Cytochrome b subunit of the bc complex K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
HKD1_k127_4328829_2 CBD_II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009894 269.0
HKD1_k127_4328829_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001688 237.0
HKD1_k127_4328829_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000002923 197.0
HKD1_k127_4328829_7 long-chain fatty acid transporting porin activity - - - 0.00001458 58.0
HKD1_k127_4331745_0 - - - - 0.000000000000000000004804 94.0
HKD1_k127_4331745_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000004267 82.0
HKD1_k127_4331745_2 M6 family metalloprotease domain protein - - - 0.000000001876 70.0
HKD1_k127_4331745_3 cellulose binding - - - 0.00000002896 62.0
HKD1_k127_4332528_0 Belongs to the ClpA ClpB family K03694 - - 2.821e-257 805.0
HKD1_k127_4332528_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 589.0
HKD1_k127_4332528_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 371.0
HKD1_k127_4339212_0 imidazolonepropionase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 454.0
HKD1_k127_4339212_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 331.0
HKD1_k127_4339212_2 peptidase inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007549 263.0
HKD1_k127_4339212_3 Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000002545 253.0
HKD1_k127_4339212_5 Tetratricopeptide repeat - - - 0.0000000000000000000000004644 111.0
HKD1_k127_4352000_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1277.0
HKD1_k127_4352000_1 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 635.0
HKD1_k127_4352000_10 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0006045 51.0
HKD1_k127_4352000_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 409.0
HKD1_k127_4352000_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 309.0
HKD1_k127_4352000_4 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 264.0
HKD1_k127_4352000_6 beta-lactamase activity K07126,K19292 - - 0.000000000000000000000000000000000000000007554 168.0
HKD1_k127_4352000_7 - - - - 0.000000000000000001679 100.0
HKD1_k127_4352000_8 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000005283 85.0
HKD1_k127_4352000_9 - - - - 0.000000000000187 79.0
HKD1_k127_4360426_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1369.0
HKD1_k127_4360426_1 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002802 291.0
HKD1_k127_4360426_2 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
HKD1_k127_4360426_3 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000006695 183.0
HKD1_k127_4360426_5 protein kinase activity - - - 0.0000000005468 67.0
HKD1_k127_4366727_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1187.0
HKD1_k127_4366727_1 transferase activity, transferring glycosyl groups K09809 - 2.7.8.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 554.0
HKD1_k127_4366727_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 450.0
HKD1_k127_4366727_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 409.0
HKD1_k127_4366727_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 366.0
HKD1_k127_4366727_5 FAD-binding domain K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 328.0
HKD1_k127_4366727_6 - - - - 0.0000000000000000004702 90.0
HKD1_k127_4366727_7 heat shock protein binding - - - 0.00000000007651 75.0
HKD1_k127_4366727_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00003529 49.0
HKD1_k127_4378381_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 606.0
HKD1_k127_4378381_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000002447 89.0
HKD1_k127_4379945_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 482.0
HKD1_k127_4379945_1 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 384.0
HKD1_k127_4379945_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 336.0
HKD1_k127_4379945_3 - - - - 0.00000000000000000000000000000000000000000000001025 187.0
HKD1_k127_439915_0 Domain of unknown function (DUF3427) - - - 1.218e-281 898.0
HKD1_k127_439915_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000001907 53.0
HKD1_k127_4402504_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 328.0
HKD1_k127_4402504_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000004388 152.0
HKD1_k127_4402504_2 Domain of unknown function (DUF4266) - - - 0.00000003327 58.0
HKD1_k127_4402504_3 Bacterial SH3 domain - - - 0.0000009687 59.0
HKD1_k127_4402504_4 PIN domain K18828 - - 0.00003236 53.0
HKD1_k127_440716_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 345.0
HKD1_k127_440716_1 NADP oxidoreductase coenzyme F420-dependent K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 271.0
HKD1_k127_440716_2 Steryl acetyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004513 262.0
HKD1_k127_440716_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000725 230.0
HKD1_k127_440716_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000004944 165.0
HKD1_k127_440716_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000001953 133.0
HKD1_k127_440716_6 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000008708 116.0
HKD1_k127_4409104_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 9.064e-199 646.0
HKD1_k127_4409104_1 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 431.0
HKD1_k127_4409104_2 ThiJ/PfpI family-like K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
HKD1_k127_4409104_3 FHA domain - - - 0.00000000000000000000000000000000000000003409 166.0
HKD1_k127_4409104_4 regulation of response to stimulus K19613 - - 0.000000000000000000000000002958 131.0
HKD1_k127_4409104_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000007819 85.0
HKD1_k127_4409104_6 Domain of unknown function (DUF4142) K08995 - - 0.0000000688 62.0
HKD1_k127_4412526_0 Domain of unknown function (DUF2088) - - - 1.929e-268 839.0
HKD1_k127_4412526_1 Male sterility protein K01897 - 6.2.1.3 3.619e-243 775.0
HKD1_k127_4412526_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 340.0
HKD1_k127_4412526_3 ATPase domain predominantly from Archaea K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003548 255.0
HKD1_k127_4412526_4 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003251 255.0
HKD1_k127_4412526_5 PEGA domain - - - 0.000000000000000000000000000000000000000000004797 182.0
HKD1_k127_4412526_6 Belongs to the ompA family K20276 - - 0.0000000000000000000000008896 114.0
HKD1_k127_4412526_7 domain, Protein - - - 0.0002027 55.0
HKD1_k127_4412526_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0002965 53.0
HKD1_k127_4424611_0 Domain of unknown function (DUF362) - - - 1.505e-200 634.0
HKD1_k127_4424611_1 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000005578 207.0
HKD1_k127_4424611_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000004747 172.0
HKD1_k127_4440321_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 342.0
HKD1_k127_4440321_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001041 243.0
HKD1_k127_4440321_2 - - - - 0.0000000000000000918 85.0
HKD1_k127_4440321_3 Planctomycete cytochrome C - - - 0.000000000001166 81.0
HKD1_k127_4445443_0 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 380.0
HKD1_k127_4445443_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000543 284.0
HKD1_k127_4445443_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000386 237.0
HKD1_k127_4475519_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
HKD1_k127_4475519_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001419 188.0
HKD1_k127_4494226_0 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 267.0
HKD1_k127_4494226_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
HKD1_k127_4547491_0 - - - - 1.574e-196 626.0
HKD1_k127_4547491_1 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 281.0
HKD1_k127_4547491_2 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000013 287.0
HKD1_k127_4547491_3 Flagellar Motor Protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000002444 235.0
HKD1_k127_4549633_0 E1-E2 ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 620.0
HKD1_k127_4549633_1 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 490.0
HKD1_k127_4549633_10 mercury ion transmembrane transporter activity - - - 0.000116 53.0
HKD1_k127_4549633_11 sensor histidine kinase with a Response regulator receiver domain K02482 - 2.7.13.3 0.0002776 49.0
HKD1_k127_4549633_3 - - - - 0.0000000000000000000000000000000004812 149.0
HKD1_k127_4549633_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000001267 122.0
HKD1_k127_4549633_5 Dynamin family - - - 0.000000000000000000000002357 115.0
HKD1_k127_4549633_6 histidine kinase A domain protein - - - 0.000000000000000001629 91.0
HKD1_k127_4549633_7 Transposase IS200 like - - - 0.0000000000000003163 84.0
HKD1_k127_4549633_8 phospholipase C K01114 - 3.1.4.3 0.0000000001587 63.0
HKD1_k127_4549633_9 Si dkey-21a6.5 - - - 0.000001268 60.0
HKD1_k127_4558550_0 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 349.0
HKD1_k127_4558550_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 337.0
HKD1_k127_4558550_2 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
HKD1_k127_4558550_3 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000003446 171.0
HKD1_k127_4560875_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 414.0
HKD1_k127_4560875_1 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 292.0
HKD1_k127_4560875_2 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000003123 94.0
HKD1_k127_458040_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 599.0
HKD1_k127_458040_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 422.0
HKD1_k127_458040_2 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000493 282.0
HKD1_k127_458040_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002382 287.0
HKD1_k127_458040_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004098 280.0
HKD1_k127_458040_5 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001598 253.0
HKD1_k127_458040_6 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
HKD1_k127_458040_7 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000009745 241.0
HKD1_k127_458040_8 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000388 224.0
HKD1_k127_4584474_0 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008433 287.0
HKD1_k127_4584474_1 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000001358 216.0
HKD1_k127_4584474_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000006621 114.0
HKD1_k127_4584474_3 Putative RNA methylase family UPF0020 - - - 0.0000000000001445 79.0
HKD1_k127_4585029_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001269 271.0
HKD1_k127_4585029_1 DNA-binding regulatory protein K03088 - - 0.000000000000000000000000000000000000000000000001153 184.0
HKD1_k127_4585029_2 Methyltransferase type 12 - - - 0.00000000000000000000000005235 112.0
HKD1_k127_4591773_0 Transcriptional regulator - - - 1.022e-206 660.0
HKD1_k127_4591773_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000632 190.0
HKD1_k127_4591773_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000273 156.0
HKD1_k127_4591773_4 chlorophyll binding - - - 0.00000000000000000000823 92.0
HKD1_k127_4591773_5 arsenical resistance operon repressor K03892 - - 0.0000000004468 68.0
HKD1_k127_4599626_0 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 8.693e-205 648.0
HKD1_k127_4599626_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 306.0
HKD1_k127_4599626_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000008748 210.0
HKD1_k127_4599626_3 Domain of unknown function (DUF4272) - - - 0.0000000000000000000000000000000000000004596 170.0
HKD1_k127_4599626_4 membrane organization - - - 0.00000000000000000000000000000146 128.0
HKD1_k127_4617419_0 Methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 479.0
HKD1_k127_4617419_1 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 420.0
HKD1_k127_4617419_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 414.0
HKD1_k127_4617419_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HKD1_k127_4617419_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000001995 175.0
HKD1_k127_4633647_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 511.0
HKD1_k127_4633647_1 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
HKD1_k127_4633647_10 acetyltransferase K03825 - - 0.00000000000000000000005829 113.0
HKD1_k127_4633647_11 Copper binding proteins, plastocyanin/azurin family - GO:0008150,GO:0008152,GO:0055114 - 0.000000000000000000008488 98.0
HKD1_k127_4633647_12 Major facilitator superfamily - - - 0.000000000000002145 89.0
HKD1_k127_4633647_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001907 79.0
HKD1_k127_4633647_14 GMC oxidoreductase - - - 0.00000000000462 78.0
HKD1_k127_4633647_2 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003645 294.0
HKD1_k127_4633647_3 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000003402 251.0
HKD1_k127_4633647_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000003994 225.0
HKD1_k127_4633647_5 Transcriptional regulator K13771,K13772 - - 0.000000000000000000000000000000000000000001153 160.0
HKD1_k127_4633647_6 - - - - 0.00000000000000000000000000000000000003261 162.0
HKD1_k127_4633647_7 - - - - 0.000000000000000000000000000000000354 143.0
HKD1_k127_4633647_8 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000006989 121.0
HKD1_k127_4633647_9 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000001703 112.0
HKD1_k127_4638101_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.007e-218 682.0
HKD1_k127_4638101_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 283.0
HKD1_k127_4638101_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
HKD1_k127_4638101_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000004337 205.0
HKD1_k127_4638101_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000001918 174.0
HKD1_k127_4638101_5 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000000002862 152.0
HKD1_k127_4638101_6 Thioredoxin - - - 0.0000000000000000000000000008672 114.0
HKD1_k127_4638126_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 563.0
HKD1_k127_4638126_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
HKD1_k127_4638126_2 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000001046 188.0
HKD1_k127_4638643_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 406.0
HKD1_k127_4638643_1 Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 331.0
HKD1_k127_4638643_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001769 157.0
HKD1_k127_4638643_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002084 117.0
HKD1_k127_4638643_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002914 115.0
HKD1_k127_4638643_13 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000007567 108.0
HKD1_k127_4638643_14 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001205 85.0
HKD1_k127_4638643_15 Ribosomal protein L30 K02907 - - 0.0000000000002579 80.0
HKD1_k127_4638643_16 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000007527 71.0
HKD1_k127_4638643_17 NB-ARC domain - - - 0.00026 50.0
HKD1_k127_4638643_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
HKD1_k127_4638643_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008364 267.0
HKD1_k127_4638643_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002615 238.0
HKD1_k127_4638643_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000132 217.0
HKD1_k127_4638643_6 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000002561 232.0
HKD1_k127_4638643_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002528 201.0
HKD1_k127_4638643_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000009806 185.0
HKD1_k127_4638643_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000004341 178.0
HKD1_k127_4649237_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 469.0
HKD1_k127_4649237_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000001871 246.0
HKD1_k127_4649237_10 Galactose oxidase, central domain - - - 0.0000007639 61.0
HKD1_k127_4649237_11 cytosine-specific methyltransferase K00558 - 2.1.1.37 0.0003279 55.0
HKD1_k127_4649237_12 Lanthionine synthetase C family protein - - - 0.0005113 54.0
HKD1_k127_4649237_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000004577 192.0
HKD1_k127_4649237_3 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000002003 180.0
HKD1_k127_4649237_4 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000001298 119.0
HKD1_k127_4649237_5 Protein of unknown function (DUF1566) - - - 0.000000000000000000000001518 120.0
HKD1_k127_4649237_6 Kelch motif - - - 0.00000000000000000000001424 117.0
HKD1_k127_4649237_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000001653 81.0
HKD1_k127_4649237_8 ribonuclease activity - - - 0.0000000000003951 71.0
HKD1_k127_4649237_9 amine dehydrogenase activity - - - 0.0000000006809 71.0
HKD1_k127_4663866_0 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 454.0
HKD1_k127_4663866_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 334.0
HKD1_k127_4663866_2 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000004015 207.0
HKD1_k127_4663866_3 Tetracycline repressor, C-terminal all-alpha domain K22106 - - 0.0000000000000000000000000000000001602 139.0
HKD1_k127_4663866_4 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.000000000000000000000006943 110.0
HKD1_k127_4678602_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 586.0
HKD1_k127_4678602_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
HKD1_k127_4678602_2 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 308.0
HKD1_k127_4678602_3 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000001299 186.0
HKD1_k127_4678602_4 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001963 182.0
HKD1_k127_4678602_5 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000002254 196.0
HKD1_k127_4688486_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.779e-240 754.0
HKD1_k127_4688486_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001434 258.0
HKD1_k127_4688486_2 glyoxalase III activity K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000465 191.0
HKD1_k127_4688486_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000007023 183.0
HKD1_k127_4688486_4 Multicopper oxidase - - - 0.000000000000000000000000001074 129.0
HKD1_k127_4688486_5 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000005456 101.0
HKD1_k127_4688486_6 Putative transmembrane protein (PGPGW) - - - 0.00000000000008045 80.0
HKD1_k127_4688486_7 cheY-homologous receiver domain - - - 0.000000006364 66.0
HKD1_k127_4688486_8 - - - - 0.000006414 57.0
HKD1_k127_4689165_0 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 567.0
HKD1_k127_4689165_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 417.0
HKD1_k127_4689165_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 428.0
HKD1_k127_4689165_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 381.0
HKD1_k127_4689165_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 348.0
HKD1_k127_4689165_5 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000003825 260.0
HKD1_k127_4689165_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000008898 75.0
HKD1_k127_4691828_0 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
HKD1_k127_4691828_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 377.0
HKD1_k127_4691828_2 - - - - 0.00000000000000000000000000000000000000000000002211 197.0
HKD1_k127_4714272_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 470.0
HKD1_k127_4714272_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 368.0
HKD1_k127_4714272_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003026 286.0
HKD1_k127_4714272_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000001415 144.0
HKD1_k127_4717940_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 307.0
HKD1_k127_4717940_1 alginic acid biosynthetic process K10297 - - 0.000001851 52.0
HKD1_k127_4737680_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 359.0
HKD1_k127_4737680_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 338.0
HKD1_k127_4737680_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003007 273.0
HKD1_k127_4737680_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 266.0
HKD1_k127_4737680_4 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006615 252.0
HKD1_k127_4737680_5 Serine aminopeptidase, S33 K06889 - - 0.0002392 47.0
HKD1_k127_4753321_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 613.0
HKD1_k127_4753321_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 527.0
HKD1_k127_4753321_2 Response regulator receiver K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 434.0
HKD1_k127_4753321_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 345.0
HKD1_k127_4753321_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000002206 173.0
HKD1_k127_4753321_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000002224 116.0
HKD1_k127_4753321_6 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.000000000000136 80.0
HKD1_k127_4753321_7 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000001883 74.0
HKD1_k127_4753321_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000005206 82.0
HKD1_k127_4753321_9 Outer membrane efflux protein - - - 0.0003664 53.0
HKD1_k127_4771230_0 DNA topoisomerase type I activity K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 8.615e-244 790.0
HKD1_k127_477295_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 499.0
HKD1_k127_477295_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 330.0
HKD1_k127_477295_2 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HKD1_k127_477295_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000817 54.0
HKD1_k127_477632_0 Tetratricopeptide repeat - - - 3.913e-239 767.0
HKD1_k127_477632_1 adenosine deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 576.0
HKD1_k127_477632_2 translation initiation factor activity K07126,K08930 - - 0.0000009545 60.0
HKD1_k127_4813951_0 Peptidase M15 K02395 - - 0.0000000000000000000000000000000000000000000005066 179.0
HKD1_k127_4813951_1 - - - - 0.000000000000000000000000000000000000000000002745 168.0
HKD1_k127_4813951_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000004068 176.0
HKD1_k127_4813951_4 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.0007599 52.0
HKD1_k127_4816669_0 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 451.0
HKD1_k127_4816669_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000004112 118.0
HKD1_k127_4816669_2 - - - - 0.000000000000000000002592 100.0
HKD1_k127_4816669_3 - - - - 0.0001341 45.0
HKD1_k127_4819353_0 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 347.0
HKD1_k127_482371_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 394.0
HKD1_k127_482371_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000539 173.0
HKD1_k127_4844923_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 508.0
HKD1_k127_4844923_1 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000001477 204.0
HKD1_k127_4844923_2 signal transduction histidine kinase - - - 0.00000000000139 79.0
HKD1_k127_4845043_0 repeat protein - - - 0.0 1528.0
HKD1_k127_4845043_1 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 469.0
HKD1_k127_4845043_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 325.0
HKD1_k127_4845043_3 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 316.0
HKD1_k127_4845043_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000005379 246.0
HKD1_k127_4845043_5 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000003495 199.0
HKD1_k127_4845043_6 - - - - 0.00000000008382 65.0
HKD1_k127_4845043_7 - - - - 0.0000002343 60.0
HKD1_k127_4849350_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 529.0
HKD1_k127_4849350_1 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000000000000000000000000000000001592 234.0
HKD1_k127_4853600_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 474.0
HKD1_k127_4853600_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 447.0
HKD1_k127_4853600_2 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000002469 256.0
HKD1_k127_4853600_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000003408 261.0
HKD1_k127_4853600_4 Flavin-nucleotide-binding protein K07005 - - 0.000000000000000000000000000000000000000000000000000000000003077 214.0
HKD1_k127_4853600_5 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000007118 193.0
HKD1_k127_4873387_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001413 242.0
HKD1_k127_4873387_1 - - - - 0.0000000000000000000000001205 120.0
HKD1_k127_4873387_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000004092 111.0
HKD1_k127_4873387_4 PilZ domain - - - 0.00000000000000005979 84.0
HKD1_k127_4896629_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
HKD1_k127_4896629_1 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 326.0
HKD1_k127_4896629_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
HKD1_k127_4896629_3 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000005657 202.0
HKD1_k127_4901072_0 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 340.0
HKD1_k127_4901072_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000004188 235.0
HKD1_k127_4901072_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
HKD1_k127_4908493_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 504.0
HKD1_k127_4908493_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000006731 224.0
HKD1_k127_4908493_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000003311 100.0
HKD1_k127_4910365_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 338.0
HKD1_k127_4910365_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004507 269.0
HKD1_k127_4910365_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000004609 129.0
HKD1_k127_4910365_4 amine dehydrogenase activity - - - 0.0003578 52.0
HKD1_k127_4912981_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 364.0
HKD1_k127_4912981_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003376 287.0
HKD1_k127_4912981_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000001321 200.0
HKD1_k127_4912981_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000001345 170.0
HKD1_k127_4912981_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000001985 172.0
HKD1_k127_4912981_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000003005 170.0
HKD1_k127_4912981_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002982 130.0
HKD1_k127_4912981_7 - - - - 0.00000000000000004864 94.0
HKD1_k127_4928020_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 568.0
HKD1_k127_4928020_1 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 474.0
HKD1_k127_4928020_10 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 379.0
HKD1_k127_4928020_11 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 358.0
HKD1_k127_4928020_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000004195 214.0
HKD1_k127_4928020_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000001426 189.0
HKD1_k127_4928020_14 deoxyribonuclease V activity K01144,K05982 - 3.1.11.5,3.1.21.7 0.000000000000000000000000000000000000000001786 160.0
HKD1_k127_4928020_15 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000001602 146.0
HKD1_k127_4928020_17 SCP-2 sterol transfer family - - - 0.0000000000000000000000000002069 119.0
HKD1_k127_4928020_18 cheY-homologous receiver domain - - - 0.00000000000000000000000000171 121.0
HKD1_k127_4928020_19 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000001165 110.0
HKD1_k127_4928020_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 482.0
HKD1_k127_4928020_21 PFAM Tetratricopeptide repeat - - - 0.00000000000009155 83.0
HKD1_k127_4928020_3 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 428.0
HKD1_k127_4928020_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 424.0
HKD1_k127_4928020_5 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 409.0
HKD1_k127_4928020_6 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 425.0
HKD1_k127_4928020_7 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 390.0
HKD1_k127_4928020_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 392.0
HKD1_k127_4928020_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 387.0
HKD1_k127_4931575_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000001154 152.0
HKD1_k127_4931575_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000002326 90.0
HKD1_k127_4931575_2 Tetratricopeptide repeat - - - 0.000175 53.0
HKD1_k127_49364_0 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 1.206e-280 894.0
HKD1_k127_49364_1 Homoserine dehydrogenase K00928,K12524 - 1.1.1.3,2.7.2.4 9.569e-254 821.0
HKD1_k127_49364_10 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000001216 138.0
HKD1_k127_49364_12 transporter component K07112 - - 0.00000000000000000000000000001014 126.0
HKD1_k127_49364_13 - - - - 0.00000000000000000000002428 117.0
HKD1_k127_49364_15 PFAM Agenet domain-containing protein - - - 0.000000005027 64.0
HKD1_k127_49364_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 462.0
HKD1_k127_49364_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 416.0
HKD1_k127_49364_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 347.0
HKD1_k127_49364_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000003838 229.0
HKD1_k127_49364_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000001849 190.0
HKD1_k127_49364_7 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000007218 195.0
HKD1_k127_49364_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000003734 177.0
HKD1_k127_49364_9 Transporter Component K07112 - - 0.000000000000000000000000000000000000007187 157.0
HKD1_k127_4938034_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 379.0
HKD1_k127_4938034_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 377.0
HKD1_k127_4938034_2 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002643 284.0
HKD1_k127_4938034_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000009009 194.0
HKD1_k127_4938034_4 Family of unknown function (DUF1028) - - - 0.00000000000000000000000001773 123.0
HKD1_k127_4939959_0 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 352.0
HKD1_k127_4939959_1 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000002074 162.0
HKD1_k127_4941625_0 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 501.0
HKD1_k127_4941625_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 405.0
HKD1_k127_4941625_10 MAPEG family - - - 0.000000000000000001008 91.0
HKD1_k127_4941625_11 hemerythrin HHE cation binding domain - - - 0.000000000000000009632 94.0
HKD1_k127_4941625_13 amine dehydrogenase activity - - - 0.0000000548 59.0
HKD1_k127_4941625_14 flagellar K02418 - - 0.00000006879 60.0
HKD1_k127_4941625_15 - - - - 0.00004764 52.0
HKD1_k127_4941625_2 Uncharacterized protein conserved in bacteria (DUF2263) - - - 0.000000000000000000000000000000000000000000000000000000000000000006225 233.0
HKD1_k127_4941625_3 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000001172 221.0
HKD1_k127_4941625_4 Alkaline phosphatase with broad substrate specificity K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000003467 230.0
HKD1_k127_4941625_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000007281 219.0
HKD1_k127_4941625_6 Type III secretion K03226 - - 0.000000000000000000000000000000000000000000000000005831 198.0
HKD1_k127_4941625_7 COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000255 189.0
HKD1_k127_4941625_8 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000008302 129.0
HKD1_k127_4941625_9 - - - - 0.0000000000000000000000002889 122.0
HKD1_k127_4947359_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 486.0
HKD1_k127_4947359_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 305.0
HKD1_k127_4947359_2 PA14 domain - - - 0.00000000000000000000000000000000000000871 153.0
HKD1_k127_4947359_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000004682 141.0
HKD1_k127_4947359_5 Family membership - - - 0.00000361 53.0
HKD1_k127_4953979_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 405.0
HKD1_k127_4953979_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000001468 137.0
HKD1_k127_4953979_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000327 88.0
HKD1_k127_4953979_3 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.000000000000000006471 94.0
HKD1_k127_4968730_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 6.344e-255 796.0
HKD1_k127_4968730_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 544.0
HKD1_k127_4968730_2 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 342.0
HKD1_k127_4968730_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
HKD1_k127_4968730_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001035 76.0
HKD1_k127_4968730_5 Dehydrogenase - - - 0.000000001563 70.0
HKD1_k127_4968730_6 repeat-containing protein - - - 0.000003636 59.0
HKD1_k127_4968730_7 Adenylate Guanylate cyclase K01768 - 4.6.1.1 0.00001633 56.0
HKD1_k127_4973101_0 ABC1 family - - - 2.413e-227 718.0
HKD1_k127_4973101_1 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000989 176.0
HKD1_k127_4973101_2 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000003182 99.0
HKD1_k127_4979305_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 529.0
HKD1_k127_4979305_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001331 243.0
HKD1_k127_4979305_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000001064 64.0
HKD1_k127_4979305_3 Rieske [2Fe-2S] domain - - - 0.00001182 53.0
HKD1_k127_4981021_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1687.0
HKD1_k127_4981021_1 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 2.495e-265 826.0
HKD1_k127_4981021_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 529.0
HKD1_k127_4981021_3 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 365.0
HKD1_k127_4981021_4 Methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001434 297.0
HKD1_k127_4981021_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000003535 182.0
HKD1_k127_4981021_7 Pseudouridine synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000001933 145.0
HKD1_k127_4981021_8 Winged helix DNA-binding domain - - - 0.0000000000000000000000005315 109.0
HKD1_k127_4981021_9 transcriptional regulator - - - 0.0000000000000000000004997 100.0
HKD1_k127_4982089_0 belongs to the thioredoxin family K20543 - - 0.00000000000000000000000000000000000001308 165.0
HKD1_k127_5010614_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 426.0
HKD1_k127_5010614_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 309.0
HKD1_k127_5010614_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000002633 249.0
HKD1_k127_5011771_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 415.0
HKD1_k127_5011771_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 357.0
HKD1_k127_5011771_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000006694 238.0
HKD1_k127_5011771_3 protein secretion by the type VII secretion system - - - 0.000000001076 69.0
HKD1_k127_5011771_4 Transglutaminase-like superfamily - - - 0.0006229 51.0
HKD1_k127_5027512_0 Cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 398.0
HKD1_k127_5027512_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 355.0
HKD1_k127_5027512_2 Insulin-induced protein (INSIG) - - - 0.000000000009105 68.0
HKD1_k127_5031848_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 587.0
HKD1_k127_5031848_1 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 326.0
HKD1_k127_5031848_4 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.000000000000000000000000000000000001506 145.0
HKD1_k127_5031848_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000001942 96.0
HKD1_k127_5031848_6 - - - - 0.0000000000000001453 93.0
HKD1_k127_5078782_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1087.0
HKD1_k127_5078782_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 9.737e-203 641.0
HKD1_k127_5078782_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000002364 133.0
HKD1_k127_5078782_12 - - - - 0.000000000000000000000000001568 115.0
HKD1_k127_5078782_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000564 112.0
HKD1_k127_5078782_14 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000002623 104.0
HKD1_k127_5078782_16 helix_turn_helix, mercury resistance - - - 0.000000000000000002515 98.0
HKD1_k127_5078782_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000009691 93.0
HKD1_k127_5078782_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000002326 88.0
HKD1_k127_5078782_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 394.0
HKD1_k127_5078782_20 electron transfer activity - - - 0.0000000000007156 81.0
HKD1_k127_5078782_21 Carbohydrate family 9 binding domain-like - - - 0.000008698 57.0
HKD1_k127_5078782_22 - K01179,K10352 - 3.2.1.4 0.00001519 55.0
HKD1_k127_5078782_23 Domain of unknown function (DUF4352) - - - 0.0001331 52.0
HKD1_k127_5078782_3 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 375.0
HKD1_k127_5078782_4 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 319.0
HKD1_k127_5078782_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 315.0
HKD1_k127_5078782_6 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003171 282.0
HKD1_k127_5078782_7 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001163 257.0
HKD1_k127_5078782_8 SMI1 / KNR4 family - - - 0.000000000000000000000000000000000000000004349 162.0
HKD1_k127_5078782_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000004064 136.0
HKD1_k127_5084510_1 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00004209 57.0
HKD1_k127_5091358_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.826e-264 820.0
HKD1_k127_5091358_1 Flavoprotein involved in K transport - - - 5.158e-222 696.0
HKD1_k127_5091358_10 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000002657 69.0
HKD1_k127_5091358_11 - - - - 0.0000000009108 72.0
HKD1_k127_5091358_12 helix-turn-helix- domain containing protein AraC type - - - 0.000005297 53.0
HKD1_k127_5091358_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 435.0
HKD1_k127_5091358_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 310.0
HKD1_k127_5091358_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000002193 193.0
HKD1_k127_5091358_5 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000525 132.0
HKD1_k127_5091358_6 Protein of unknown function (DUF523) - - - 0.00000000000000006929 90.0
HKD1_k127_5091358_7 peptidyl-tyrosine sulfation - - - 0.0000000000007625 72.0
HKD1_k127_5091358_9 - - - - 0.0000000000223 74.0
HKD1_k127_5101715_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 412.0
HKD1_k127_5101715_1 Type III K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000004588 177.0
HKD1_k127_5101715_2 protein secretion - - - 0.00000003956 64.0
HKD1_k127_5103503_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 582.0
HKD1_k127_5121512_1 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000002061 226.0
HKD1_k127_5121512_2 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000002363 207.0
HKD1_k127_5121512_3 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000001582 128.0
HKD1_k127_5121512_5 family 25 - - - 0.000000000000008071 86.0
HKD1_k127_5133524_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.939e-292 936.0
HKD1_k127_5133524_1 protein kinase activity - - - 3.528e-272 846.0
HKD1_k127_5133524_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.449e-212 668.0
HKD1_k127_5133524_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 346.0
HKD1_k127_5133524_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 316.0
HKD1_k127_5133524_5 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003489 264.0
HKD1_k127_5143207_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000001092 162.0
HKD1_k127_5143207_2 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000371 154.0
HKD1_k127_5143207_3 EAL domain - - - 0.0000000000000000000000000000000000002743 151.0
HKD1_k127_5143207_4 HmuY protein - - - 0.0000004437 63.0
HKD1_k127_5143207_5 TonB dependent receptor K16089 - - 0.0008195 42.0
HKD1_k127_5143662_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 479.0
HKD1_k127_5143662_1 light absorption - - - 0.00000000000000000000000000000000000000000000000000005796 190.0
HKD1_k127_5143662_2 FHA domain - - - 0.00000000000000000000000000000000000000000007563 175.0
HKD1_k127_5143662_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000001129 156.0
HKD1_k127_5143662_4 Transcriptional regulator - - - 0.000000000000000000000000000000000011 149.0
HKD1_k127_5143662_5 PilZ domain K08884 - 2.7.11.1 0.0000000000000002654 90.0
HKD1_k127_5151635_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 445.0
HKD1_k127_5151635_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 338.0
HKD1_k127_5151635_2 HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 252.0
HKD1_k127_5151635_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000002079 169.0
HKD1_k127_5151635_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000002184 127.0
HKD1_k127_5151635_5 Glyoxalase-like domain K06996 - - 0.000000000000000000000000003195 120.0
HKD1_k127_5151635_6 Phosphocarrier protein HPR K11189 - - 0.000000000000000000000001029 108.0
HKD1_k127_5151635_7 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.000000000000000004383 93.0
HKD1_k127_5151635_8 domain, Protein K20276 - - 0.000001168 60.0
HKD1_k127_5153905_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 7.217e-238 747.0
HKD1_k127_5153905_1 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 334.0
HKD1_k127_5153905_2 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000000007293 61.0
HKD1_k127_51555_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 585.0
HKD1_k127_51555_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008732 278.0
HKD1_k127_51555_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002701 254.0
HKD1_k127_51555_4 SEC-C Motif Domain Protein K09858 - - 0.000000000000000000000000000004868 126.0
HKD1_k127_51555_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000008085 122.0
HKD1_k127_51555_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000006315 94.0
HKD1_k127_51555_7 oxidoreductase activity K00337,K03333,K04771,K07114 - 1.1.3.6,1.6.5.3,3.4.21.107 0.00000000000000008378 87.0
HKD1_k127_51555_8 Domain of unknown function (DUF4215) - - - 0.0000005438 57.0
HKD1_k127_51555_9 transcriptional regulator - - - 0.0001619 49.0
HKD1_k127_5161700_0 Protein phosphatase 2A homologues, catalytic domain. - - - 1.378e-196 647.0
HKD1_k127_5161700_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 527.0
HKD1_k127_5161700_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 436.0
HKD1_k127_5161700_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002387 270.0
HKD1_k127_5161700_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000002573 167.0
HKD1_k127_5161700_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.0000000000000000000000000000000000000005714 166.0
HKD1_k127_5161700_7 Stigma-specific protein, Stig1 - - - 0.000000000000000000000000001161 124.0
HKD1_k127_5161700_9 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000003205 59.0
HKD1_k127_5172643_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 4.129e-216 687.0
HKD1_k127_5172643_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
HKD1_k127_5172643_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000001543 217.0
HKD1_k127_5172643_3 cell envelope organization K05807,K08309 - - 0.000000000000001613 89.0
HKD1_k127_5178648_1 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000007377 231.0
HKD1_k127_5178648_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000001431 142.0
HKD1_k127_5182019_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 434.0
HKD1_k127_5182019_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 399.0
HKD1_k127_5182019_2 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 271.0
HKD1_k127_5182019_3 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000003266 185.0
HKD1_k127_5182019_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000002145 64.0
HKD1_k127_5187341_0 - - - - 6.506e-194 641.0
HKD1_k127_5187341_1 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004092 247.0
HKD1_k127_5187341_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000002313 228.0
HKD1_k127_5187341_3 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000001357 201.0
HKD1_k127_5187341_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000003432 153.0
HKD1_k127_5187341_5 Cytochrome c - - - 0.00000000000000000000001069 115.0
HKD1_k127_5187341_6 Rieske [2Fe-2S] domain K05710,K18248 - - 0.000000000008457 69.0
HKD1_k127_5187341_7 PFAM Rhomboid family protein K07059 - - 0.0001277 49.0
HKD1_k127_520358_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1045.0
HKD1_k127_520358_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 544.0
HKD1_k127_520358_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 448.0
HKD1_k127_520358_3 Glycosyl transferases group 1 - - - 0.000000000043 71.0
HKD1_k127_5204935_2 sporulation resulting in formation of a cellular spore - - - 0.00000000002478 74.0
HKD1_k127_5213216_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.039e-230 746.0
HKD1_k127_5213216_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 391.0
HKD1_k127_5213216_10 - - - - 0.00000000000000001622 93.0
HKD1_k127_5213216_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 352.0
HKD1_k127_5213216_3 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 313.0
HKD1_k127_5213216_4 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
HKD1_k127_5213216_5 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000002379 221.0
HKD1_k127_5213216_6 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000001111 225.0
HKD1_k127_5213216_7 - - - - 0.000000000000000000000000000000000002812 142.0
HKD1_k127_5213216_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000001114 96.0
HKD1_k127_5213216_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000001851 99.0
HKD1_k127_5217416_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1025.0
HKD1_k127_5217416_1 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 444.0
HKD1_k127_5217416_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000006877 100.0
HKD1_k127_5217416_11 M6 family metalloprotease domain protein - - - 0.00000000271 70.0
HKD1_k127_5217416_13 calcium ion binding - - - 0.0003054 51.0
HKD1_k127_5217416_2 Cytochrome P450 K21164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 381.0
HKD1_k127_5217416_3 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
HKD1_k127_5217416_4 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
HKD1_k127_5217416_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000002726 246.0
HKD1_k127_5217416_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000006961 216.0
HKD1_k127_5217416_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000002322 165.0
HKD1_k127_5217416_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001025 111.0
HKD1_k127_5217416_9 Membrane bound O-acyl transferase family - - - 0.0000000000000000000006898 106.0
HKD1_k127_5233658_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 6.3e-235 739.0
HKD1_k127_5233658_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 1.102e-198 634.0
HKD1_k127_5233658_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 493.0
HKD1_k127_5233658_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 372.0
HKD1_k127_5233658_4 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 333.0
HKD1_k127_5233658_5 phosphoserine phosphatase activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001831 286.0
HKD1_k127_5233658_6 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000007597 234.0
HKD1_k127_5233658_7 antisigma factor binding K04749,K06378 - - 0.00000000000000000000000003857 111.0
HKD1_k127_5233658_8 Histidine kinase K07642 - 2.7.13.3 0.0000000000000004903 89.0
HKD1_k127_5242645_0 synthase homocitrate synthase family K01649 - 2.3.3.13 1.498e-205 652.0
HKD1_k127_5242645_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 541.0
HKD1_k127_5242645_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 425.0
HKD1_k127_5242645_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 384.0
HKD1_k127_5242645_4 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 299.0
HKD1_k127_5242645_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 299.0
HKD1_k127_5242645_6 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000009994 246.0
HKD1_k127_5242645_7 Cytochrome c, mono- and diheme variants - - - 0.0000000007919 70.0
HKD1_k127_527772_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000004433 199.0
HKD1_k127_527772_1 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.000000000000000000000000000000000000000000001107 185.0
HKD1_k127_527772_2 capsule polysaccharide biosynthetic process - - - 0.0000000000000000000000002492 121.0
HKD1_k127_528672_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 592.0
HKD1_k127_528672_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
HKD1_k127_528672_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000002324 211.0
HKD1_k127_528672_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001639 178.0
HKD1_k127_528672_4 chlorophyll binding - - - 0.00000000000000000000008853 108.0
HKD1_k127_528672_5 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.000000000001516 67.0
HKD1_k127_528672_6 Domain of unknown function (DUF4884) - - - 0.000000002209 62.0
HKD1_k127_5288626_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 302.0
HKD1_k127_5288626_1 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001641 289.0
HKD1_k127_5288626_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004791 265.0
HKD1_k127_5288626_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000001948 220.0
HKD1_k127_5288626_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000002637 143.0
HKD1_k127_5288626_5 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000862 152.0
HKD1_k127_5288626_6 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000006745 123.0
HKD1_k127_5288626_7 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000185 90.0
HKD1_k127_5288626_8 Secretory lipase - - - 0.0000000000001427 83.0
HKD1_k127_5288626_9 - - - - 0.00008475 53.0
HKD1_k127_5320406_0 ABC-type multidrug transport system ATPase component K21397 - - 1.018e-229 722.0
HKD1_k127_5320406_1 COG1061 DNA or RNA helicases of superfamily II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000287 299.0
HKD1_k127_5320406_2 ABC-type multidrug transport system ATPase component K21397 - - 0.00000000000000000000000000000006267 124.0
HKD1_k127_5320406_3 Protein of unknown function (DUF790) K09744 - - 0.000000000000000000000000001864 125.0
HKD1_k127_5320406_4 - - - - 0.000000000000000000002569 109.0
HKD1_k127_5320406_5 PFAM Polyketide cyclase dehydrase K03396 - 4.4.1.22 0.0001992 53.0
HKD1_k127_532926_0 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 570.0
HKD1_k127_532926_1 DoxX - - - 0.00000000000000000000000000000000000000006323 155.0
HKD1_k127_532926_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000006381 157.0
HKD1_k127_532926_3 Domain of unknown function (DUF5011) - - - 0.000000000000000000000316 113.0
HKD1_k127_5333864_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 535.0
HKD1_k127_5333864_1 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 487.0
HKD1_k127_5333864_10 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000009461 83.0
HKD1_k127_5333864_11 Homologues of snake disintegrins - - - 0.000002761 61.0
HKD1_k127_5333864_2 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 480.0
HKD1_k127_5333864_3 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 473.0
HKD1_k127_5333864_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 362.0
HKD1_k127_5333864_5 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 332.0
HKD1_k127_5333864_6 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 335.0
HKD1_k127_5333864_7 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008779 278.0
HKD1_k127_5333864_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000002751 210.0
HKD1_k127_5333864_9 antibiotic catabolic process - - - 0.000000000000004436 90.0
HKD1_k127_5334130_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 551.0
HKD1_k127_5334130_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 456.0
HKD1_k127_5334130_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000008663 248.0
HKD1_k127_5334130_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000741 208.0
HKD1_k127_5334130_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000005486 121.0
HKD1_k127_5334130_5 - - - - 0.00000000000000000000000003856 114.0
HKD1_k127_5346531_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 640.0
HKD1_k127_5346531_1 Flagellar Motor Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 560.0
HKD1_k127_534998_0 RmlD substrate binding domain K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 411.0
HKD1_k127_534998_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 356.0
HKD1_k127_534998_2 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003831 254.0
HKD1_k127_535386_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 457.0
HKD1_k127_535386_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000001145 151.0
HKD1_k127_535386_3 IMG reference gene - - - 0.00000001063 66.0
HKD1_k127_5353937_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 8.375e-273 859.0
HKD1_k127_5353937_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 447.0
HKD1_k127_5353937_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000663 258.0
HKD1_k127_5353937_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000003103 209.0
HKD1_k127_5353937_4 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000003063 173.0
HKD1_k127_5353937_5 SCO1/SenC K07152 - - 0.0000000000000000000000000000002476 140.0
HKD1_k127_5353937_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001033 95.0
HKD1_k127_53543_0 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 487.0
HKD1_k127_53543_1 Belongs to the aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 474.0
HKD1_k127_53543_10 oxidoreductase activity K07114 - - 0.000000003315 59.0
HKD1_k127_53543_11 Glycosyl transferases group 1 - - - 0.000000003509 70.0
HKD1_k127_53543_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 366.0
HKD1_k127_53543_3 N-4 methylation of cytosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005959 264.0
HKD1_k127_53543_4 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000017 235.0
HKD1_k127_53543_5 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
HKD1_k127_53543_6 sulfuric ester hydrolase activity - - - 0.0000000000000000000000000000000000000000001942 173.0
HKD1_k127_53543_7 PFAM YCII-related - - - 0.0000000000000000000000000211 112.0
HKD1_k127_53543_8 Family membership - - - 0.00000000000000000000000008011 109.0
HKD1_k127_53543_9 metallopeptidase activity - - - 0.00000000000000004579 95.0
HKD1_k127_5355666_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 314.0
HKD1_k127_5355666_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000245 216.0
HKD1_k127_5355666_2 Peptidase M16 - - - 0.00000000000000000000000000000000000000004276 166.0
HKD1_k127_5368503_0 DNA helicase K03654 - 3.6.4.12 2.616e-205 657.0
HKD1_k127_5368503_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000007382 154.0
HKD1_k127_5368503_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000001301 87.0
HKD1_k127_5369380_0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 407.0
HKD1_k127_5369380_1 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 370.0
HKD1_k127_5369380_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 362.0
HKD1_k127_5369380_3 - - - - 0.000000000000000000000000000000000000000000000000000000002044 207.0
HKD1_k127_5369380_4 Fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000008045 192.0
HKD1_k127_5372519_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 338.0
HKD1_k127_5372519_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000113 186.0
HKD1_k127_5372519_4 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000001205 180.0
HKD1_k127_5372519_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000001423 156.0
HKD1_k127_5372519_6 SPFH domain / Band 7 family - - - 0.000000000000000001529 89.0
HKD1_k127_5379456_0 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 402.0
HKD1_k127_5379456_1 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 373.0
HKD1_k127_5379456_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000001788 143.0
HKD1_k127_5381550_0 beta-lactamase - - - 6.013e-203 655.0
HKD1_k127_5381550_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000005834 52.0
HKD1_k127_5382355_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 445.0
HKD1_k127_5382355_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000002247 192.0
HKD1_k127_5382355_2 - - - - 0.00000000000002892 82.0
HKD1_k127_5417028_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 491.0
HKD1_k127_5417028_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000006163 164.0
HKD1_k127_5417028_2 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000008454 153.0
HKD1_k127_5417028_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000002306 82.0
HKD1_k127_5438139_0 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000523 256.0
HKD1_k127_5438139_1 - - - - 0.000000000000000000000000000000000000000000000000002059 195.0
HKD1_k127_543909_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 4.259e-195 642.0
HKD1_k127_543909_1 amine oxidase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 583.0
HKD1_k127_543909_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003218 269.0
HKD1_k127_543909_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007781 276.0
HKD1_k127_543909_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001845 271.0
HKD1_k127_543909_5 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001444 211.0
HKD1_k127_543909_7 protein kinase activity - - - 0.000000000000000000000003655 108.0
HKD1_k127_5440408_0 two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 437.0
HKD1_k127_5440408_1 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 311.0
HKD1_k127_5440408_2 - - - - 0.00000000000000000000000002725 108.0
HKD1_k127_5468674_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.337e-266 860.0
HKD1_k127_5468674_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 483.0
HKD1_k127_5468674_10 PAS fold - - - 0.000000004427 69.0
HKD1_k127_5468674_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 374.0
HKD1_k127_5468674_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 342.0
HKD1_k127_5468674_4 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 322.0
HKD1_k127_5468674_5 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 305.0
HKD1_k127_5468674_6 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
HKD1_k127_5468674_7 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000007267 171.0
HKD1_k127_5468674_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000003465 87.0
HKD1_k127_5471950_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 7.876e-245 766.0
HKD1_k127_5471950_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 388.0
HKD1_k127_5471950_2 amine dehydrogenase activity - - - 0.0000000000000000000006018 110.0
HKD1_k127_5471950_3 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000001049 92.0
HKD1_k127_5471950_4 RHS protein - - - 0.0002748 54.0
HKD1_k127_5477691_0 Belongs to the ompA family - - - 0.0000000000000004662 92.0
HKD1_k127_5477691_1 peptidyl-tyrosine sulfation - - - 0.000000000000005057 88.0
HKD1_k127_5477691_2 - - - - 0.000002557 59.0
HKD1_k127_548292_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 477.0
HKD1_k127_548292_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 473.0
HKD1_k127_548292_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001096 254.0
HKD1_k127_548292_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001306 255.0
HKD1_k127_548292_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000004943 235.0
HKD1_k127_548292_5 PFAM RES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000007401 222.0
HKD1_k127_548292_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000008617 222.0
HKD1_k127_548292_7 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000002367 148.0
HKD1_k127_548292_8 NAD(P)H-binding - - - 0.000000000000000000000000000000001183 138.0
HKD1_k127_548292_9 - - - - 0.000000000000000000000000008046 128.0
HKD1_k127_5485111_0 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 555.0
HKD1_k127_5485111_1 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 414.0
HKD1_k127_5485111_2 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 304.0
HKD1_k127_5485111_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000007365 56.0
HKD1_k127_5485111_5 P-aminobenzoate N-oxygenase AurF - - - 0.000002169 61.0
HKD1_k127_5488279_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 316.0
HKD1_k127_5488279_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 282.0
HKD1_k127_5488279_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000001652 56.0
HKD1_k127_5488279_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000016 64.0
HKD1_k127_5488279_6 PFAM Metallophosphoesterase - - - 0.00003493 50.0
HKD1_k127_5496920_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 473.0
HKD1_k127_5496920_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.00000000000000000000000000000003014 134.0
HKD1_k127_5497130_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 522.0
HKD1_k127_5497130_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000002324 193.0
HKD1_k127_5497130_2 oxidoreductase - - - 0.00000000000000000000000000000000000000001201 166.0
HKD1_k127_5497130_3 membrane organization K07126,K07277 - - 0.000000000000000000000000000000000276 147.0
HKD1_k127_5497130_4 Stigma-specific protein, Stig1 - - - 0.00000000000000000001204 105.0
HKD1_k127_5497130_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000004109 94.0
HKD1_k127_5497130_7 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000241 66.0
HKD1_k127_5497130_8 Calcineurin-like phosphoesterase - - - 0.000008841 58.0
HKD1_k127_5497130_9 YjbR - - - 0.00008333 51.0
HKD1_k127_5500956_0 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002951 250.0
HKD1_k127_5500956_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000454 193.0
HKD1_k127_5500956_2 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000000001326 181.0
HKD1_k127_5500956_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000159 117.0
HKD1_k127_551097_0 Family membership - - - 4.654e-222 720.0
HKD1_k127_551097_1 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 488.0
HKD1_k127_551097_2 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 314.0
HKD1_k127_551097_3 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006078 292.0
HKD1_k127_551097_4 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003446 240.0
HKD1_k127_551097_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000005834 158.0
HKD1_k127_551097_6 diguanylate cyclase - - - 0.000000000000000000000000000008233 132.0
HKD1_k127_551097_7 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000001901 133.0
HKD1_k127_5537467_0 Tetratricopeptide repeat - - - 0.0 2627.0
HKD1_k127_5537467_1 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 404.0
HKD1_k127_5537467_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000001152 241.0
HKD1_k127_5537467_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000001835 209.0
HKD1_k127_5537467_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000002247 113.0
HKD1_k127_5555005_0 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004051 244.0
HKD1_k127_5555005_1 Flagellar filament outer layer protein Flaa - - - 0.0000000000000000000000000000000000000000005834 173.0
HKD1_k127_5555005_2 Putative DNA-binding domain - - - 0.0000000000000000001946 101.0
HKD1_k127_5556315_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 491.0
HKD1_k127_5556315_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 355.0
HKD1_k127_5556315_2 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 339.0
HKD1_k127_5556315_3 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005125 260.0
HKD1_k127_5556315_4 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007442 239.0
HKD1_k127_5556315_5 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000008354 170.0
HKD1_k127_5556315_6 repeat protein - - - 0.00000000000000000000000749 111.0
HKD1_k127_5556315_7 Ribbon-helix-helix domain - - - 0.00000000000000000001582 93.0
HKD1_k127_5608440_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 533.0
HKD1_k127_5608440_1 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 377.0
HKD1_k127_5608440_3 Alpha-amylase domain - - - 0.000000000000000000000000000000000000000000000000000000000971 224.0
HKD1_k127_5611526_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 3.736e-210 667.0
HKD1_k127_5611526_1 ATPase (AAA) - - - 0.0000000000000000000000000000000000004615 142.0
HKD1_k127_5611526_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000002204 142.0
HKD1_k127_5611526_3 Domain of unknown function (DUF1963) - - - 0.0000000000000008889 92.0
HKD1_k127_5611526_4 Leucine-rich repeat and IQ domain-containing protein 4 - GO:0003674,GO:0005215,GO:0005216,GO:0005225,GO:0005253,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0007154,GO:0007165,GO:0008150,GO:0008509,GO:0009987,GO:0015075,GO:0015103,GO:0015267,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0023052,GO:0031224,GO:0032991,GO:0034220,GO:0034702,GO:0044424,GO:0044425,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0065007,GO:0071944,GO:0098656,GO:0098796,GO:1902495,GO:1990351 - 0.000000001224 72.0
HKD1_k127_5620644_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 8.24e-209 656.0
HKD1_k127_5620644_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000002304 220.0
HKD1_k127_5620644_3 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000001087 125.0
HKD1_k127_5620644_4 - - - - 0.00000000000000000000001785 114.0
HKD1_k127_5620644_5 - - - - 0.0000000000000001465 93.0
HKD1_k127_5620644_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000003804 77.0
HKD1_k127_5620644_7 - - - - 0.0000000405 56.0
HKD1_k127_5620644_8 - - - - 0.000007389 48.0
HKD1_k127_5625111_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 454.0
HKD1_k127_5625111_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000005765 206.0
HKD1_k127_5625111_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000002692 121.0
HKD1_k127_5630467_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 497.0
HKD1_k127_5630467_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 461.0
HKD1_k127_5630467_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 287.0
HKD1_k127_5630467_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006703 260.0
HKD1_k127_5630467_4 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006725 273.0
HKD1_k127_5630467_7 histone H2A K63-linked ubiquitination - - - 0.000000028 61.0
HKD1_k127_5634249_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 431.0
HKD1_k127_5634249_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
HKD1_k127_5634249_2 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD1_k127_5634249_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000002971 205.0
HKD1_k127_5635651_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001081 268.0
HKD1_k127_5635651_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000000000000000000724 210.0
HKD1_k127_5635651_2 Polysulphide reductase K00185 - - 0.00000000000000000000000001901 127.0
HKD1_k127_5642745_0 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 333.0
HKD1_k127_5642745_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 332.0
HKD1_k127_5642745_2 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000001107 156.0
HKD1_k127_5642745_3 - - - - 0.000000000002195 73.0
HKD1_k127_5642745_4 serine threonine protein kinase K08884 - 2.7.11.1 0.000001346 56.0
HKD1_k127_5643223_0 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 366.0
HKD1_k127_5643223_1 short chain dehydrogenase reductase family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
HKD1_k127_5643223_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007639 284.0
HKD1_k127_5643223_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009348 263.0
HKD1_k127_5643223_4 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000006938 203.0
HKD1_k127_5643223_5 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000004788 199.0
HKD1_k127_5643223_6 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000003999 178.0
HKD1_k127_566758_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.518e-288 898.0
HKD1_k127_566758_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 522.0
HKD1_k127_566758_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000006069 292.0
HKD1_k127_566758_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000007689 229.0
HKD1_k127_566758_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000001166 96.0
HKD1_k127_566758_6 - - - - 0.00001163 56.0
HKD1_k127_567701_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 372.0
HKD1_k127_567701_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000006533 176.0
HKD1_k127_5689567_0 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000009439 214.0
HKD1_k127_5689567_1 Protein of unknown function (DUF4241) - - - 0.0000000001016 72.0
HKD1_k127_5692151_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 473.0
HKD1_k127_5692151_1 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 417.0
HKD1_k127_5692151_2 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
HKD1_k127_5692151_4 - - - - 0.00000000000000000000000000000001172 136.0
HKD1_k127_5692151_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000001101 64.0
HKD1_k127_5692151_6 cytochrome - - - 0.00008087 49.0
HKD1_k127_5706580_0 Heat shock 70 kDa protein K04043 - - 1.094e-230 722.0
HKD1_k127_5706580_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 426.0
HKD1_k127_5718874_0 DNA mismatch repair protein K07456 - - 1.307e-199 636.0
HKD1_k127_5718874_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 639.0
HKD1_k127_5718874_10 GMP synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 321.0
HKD1_k127_5718874_11 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 337.0
HKD1_k127_5718874_12 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
HKD1_k127_5718874_13 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000001691 238.0
HKD1_k127_5718874_14 General secretion pathway protein C K02452 - - 0.0000000000000000000000000000003318 130.0
HKD1_k127_5718874_15 trisaccharide binding - - - 0.00000000000000000000003333 112.0
HKD1_k127_5718874_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 601.0
HKD1_k127_5718874_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 549.0
HKD1_k127_5718874_4 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 545.0
HKD1_k127_5718874_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
HKD1_k127_5718874_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 394.0
HKD1_k127_5718874_7 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 394.0
HKD1_k127_5718874_8 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 338.0
HKD1_k127_5718874_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 347.0
HKD1_k127_5720830_0 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 494.0
HKD1_k127_5720830_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 289.0
HKD1_k127_5720830_2 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000002588 178.0
HKD1_k127_572344_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 338.0
HKD1_k127_572344_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 334.0
HKD1_k127_572344_2 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000001556 257.0
HKD1_k127_572344_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000005242 131.0
HKD1_k127_572344_4 Stigma-specific protein, Stig1 - - - 0.000000000000000000000001361 117.0
HKD1_k127_572344_5 - - - - 0.00000000000000001045 96.0
HKD1_k127_572344_7 FES K10773 - 4.2.99.18 0.000176 44.0
HKD1_k127_572344_8 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00466,K09879 - 1.13.12.3 0.0009494 52.0
HKD1_k127_5743670_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 422.0
HKD1_k127_5743670_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000006366 108.0
HKD1_k127_5749657_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 509.0
HKD1_k127_5749657_1 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 291.0
HKD1_k127_5749657_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000002725 100.0
HKD1_k127_5749657_3 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 0.000002453 53.0
HKD1_k127_5756660_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 642.0
HKD1_k127_5756660_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 490.0
HKD1_k127_5756660_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 355.0
HKD1_k127_5756660_3 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 316.0
HKD1_k127_5756660_4 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000001559 137.0
HKD1_k127_5756660_5 Protein of unknown function (DUF962) - - - 0.00000000000000000000000186 106.0
HKD1_k127_5792905_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 595.0
HKD1_k127_5792905_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 405.0
HKD1_k127_5792905_2 6-phosphogluconate dehydrogenase NAD-binding K00042 - 1.1.1.60 0.000000000000000000000000000000000000000001594 166.0
HKD1_k127_5807685_0 MMPL family K07003 - - 4.412e-199 638.0
HKD1_k127_5807685_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.00005593 57.0
HKD1_k127_5827296_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 419.0
HKD1_k127_5827296_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000009222 168.0
HKD1_k127_5827296_2 - - - - 0.0000000000000004001 90.0
HKD1_k127_5827296_3 domain, Protein - - - 0.00000002276 65.0
HKD1_k127_5827842_0 Aminotransferase K01845 - 5.4.3.8 3.674e-199 627.0
HKD1_k127_5827842_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 562.0
HKD1_k127_5827842_10 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HKD1_k127_5827842_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000006471 233.0
HKD1_k127_5827842_12 protein kinase activity - - - 0.000000000000000000000000000000000000000000000007079 197.0
HKD1_k127_5827842_13 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000006147 179.0
HKD1_k127_5827842_14 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000007051 186.0
HKD1_k127_5827842_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000001145 163.0
HKD1_k127_5827842_17 - - - - 0.00000000000000000000000000003442 126.0
HKD1_k127_5827842_18 Stigma-specific protein, Stig1 - - - 0.000000000000000000000001776 115.0
HKD1_k127_5827842_19 PFAM CHAD domain containing protein - - - 0.0000000000000000000006985 105.0
HKD1_k127_5827842_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 518.0
HKD1_k127_5827842_20 Helix-hairpin-helix motif K02237 - - 0.0000000000000004474 89.0
HKD1_k127_5827842_21 WD40-like Beta Propeller Repeat - - - 0.00000000125 72.0
HKD1_k127_5827842_22 - - - - 0.00009176 48.0
HKD1_k127_5827842_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 485.0
HKD1_k127_5827842_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 478.0
HKD1_k127_5827842_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 413.0
HKD1_k127_5827842_6 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 407.0
HKD1_k127_5827842_7 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
HKD1_k127_5827842_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001042 291.0
HKD1_k127_5827842_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003082 262.0
HKD1_k127_584067_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 412.0
HKD1_k127_584067_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 376.0
HKD1_k127_584067_2 - - - - 0.000000000000000000000000000000000000000000000000006078 196.0
HKD1_k127_584067_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000001871 152.0
HKD1_k127_584067_5 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000003272 155.0
HKD1_k127_584067_6 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000002729 142.0
HKD1_k127_5843197_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 366.0
HKD1_k127_5843197_1 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HKD1_k127_5843197_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000001575 165.0
HKD1_k127_5843197_3 - - - - 0.0000000000000003198 89.0
HKD1_k127_5843197_4 helicase domain protein - - - 0.000000000000005589 81.0
HKD1_k127_584386_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 606.0
HKD1_k127_584386_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 424.0
HKD1_k127_584386_10 serine-type endopeptidase activity - - - 0.000006984 59.0
HKD1_k127_584386_2 k transport K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 394.0
HKD1_k127_584386_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000007338 233.0
HKD1_k127_584386_4 FR47-like protein - - - 0.0000000000000000000000000000000000000000000008447 169.0
HKD1_k127_584386_5 Trypsin-like serine protease - - - 0.000000000000000000000000000000001908 142.0
HKD1_k127_584386_6 membrane - - - 0.0000000000000000000000009685 115.0
HKD1_k127_584386_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000002901 93.0
HKD1_k127_584386_8 transcriptional regulator K09681 - - 0.0000000000000002064 91.0
HKD1_k127_5883402_0 response regulator K07713 - - 2.799e-213 675.0
HKD1_k127_5883402_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 324.0
HKD1_k127_5883402_2 General secretion pathway protein C K02452 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
HKD1_k127_5883402_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000001155 196.0
HKD1_k127_5883402_5 Ferredoxin - - - 0.000000000000000000000008034 104.0
HKD1_k127_593092_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000001312 62.0
HKD1_k127_593092_1 G-D-S-L family lipolytic protein - - - 0.0000005929 62.0
HKD1_k127_5939380_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 554.0
HKD1_k127_5939380_2 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000000000000000000000000569 164.0
HKD1_k127_5939380_3 Acyltransferase family - - - 0.0000000000000000000000005521 120.0
HKD1_k127_5939380_4 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.000000000692 67.0
HKD1_k127_6004220_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.167e-202 638.0
HKD1_k127_6004220_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 555.0
HKD1_k127_6004220_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 453.0
HKD1_k127_6004220_3 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000001063 228.0
HKD1_k127_6004220_5 - - - - 0.00000000002121 70.0
HKD1_k127_6008122_0 Family membership - - - 1.011e-258 847.0
HKD1_k127_6008122_1 heat shock protein binding - - - 4.472e-225 727.0
HKD1_k127_6008122_10 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000002512 209.0
HKD1_k127_6008122_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000004744 188.0
HKD1_k127_6008122_12 - K07283 - - 0.0000000000000000000000000000000000000000000000004515 192.0
HKD1_k127_6008122_15 Cytochrome c - - - 0.0000000000000000000000858 111.0
HKD1_k127_6008122_16 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000006393 87.0
HKD1_k127_6008122_17 Forkhead associated domain - - - 0.000000000000004112 77.0
HKD1_k127_6008122_19 Cytochrome c - - - 0.000000002205 62.0
HKD1_k127_6008122_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.276e-196 634.0
HKD1_k127_6008122_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 453.0
HKD1_k127_6008122_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 386.0
HKD1_k127_6008122_5 PFAM sigma-54 factor interaction domain-containing protein K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 376.0
HKD1_k127_6008122_6 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001736 278.0
HKD1_k127_6008122_7 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000004523 239.0
HKD1_k127_6008122_8 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000001504 216.0
HKD1_k127_6008122_9 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000003026 201.0
HKD1_k127_6008123_0 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000002409 161.0
HKD1_k127_6008123_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000001297 136.0
HKD1_k127_6008123_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000001712 137.0
HKD1_k127_6008123_4 Thioredoxin-like - - - 0.0000000000000000000000000000003271 135.0
HKD1_k127_6010530_0 Belongs to the aldehyde dehydrogenase family - - - 2.352e-202 638.0
HKD1_k127_6010530_1 Predicted nucleotidyltransferase K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 504.0
HKD1_k127_6010530_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 382.0
HKD1_k127_6010530_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 345.0
HKD1_k127_6010530_4 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005893 268.0
HKD1_k127_6010530_5 - - - - 0.000000000000000000000000000000000000000000000001996 181.0
HKD1_k127_6010530_6 - - - - 0.00000000000000000000002466 109.0
HKD1_k127_6023496_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 547.0
HKD1_k127_6023496_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 468.0
HKD1_k127_6023496_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 394.0
HKD1_k127_6023496_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009978 283.0
HKD1_k127_6023496_4 DUF218 domain - - - 0.0000000000000000000000000002377 121.0
HKD1_k127_6032985_0 ABC transporter, ATP-binding protein - - - 1.692e-207 657.0
HKD1_k127_6032985_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 381.0
HKD1_k127_6032985_2 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 322.0
HKD1_k127_6032985_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 301.0
HKD1_k127_6032985_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004005 273.0
HKD1_k127_6032985_5 domain protein - - - 0.00000000000000002055 86.0
HKD1_k127_6032985_7 Protein kinase domain - - - 0.0003512 47.0
HKD1_k127_6034807_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 495.0
HKD1_k127_6034807_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000002206 120.0
HKD1_k127_6057648_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 484.0
HKD1_k127_6057648_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 432.0
HKD1_k127_6057648_2 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 332.0
HKD1_k127_6057648_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 265.0
HKD1_k127_6057648_4 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000002552 217.0
HKD1_k127_6057864_0 synthetase K01895 - 6.2.1.1 6.628e-252 789.0
HKD1_k127_6057864_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 482.0
HKD1_k127_6057864_2 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 399.0
HKD1_k127_6057864_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 420.0
HKD1_k127_6057864_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000002348 206.0
HKD1_k127_6057864_5 Bacterial transferase hexapeptide (six repeats) K00661 - 2.3.1.79 0.0000000000000000000000000000000000000007926 156.0
HKD1_k127_6057864_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000001098 144.0
HKD1_k127_6057864_7 Phosphopantetheine attachment site - - - 0.000000000000000311 91.0
HKD1_k127_6057864_8 Acetyltransferase (GNAT) domain - - - 0.000000003809 69.0
HKD1_k127_6070091_0 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000004623 223.0
HKD1_k127_6070091_1 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000001168 200.0
HKD1_k127_6070091_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000614 187.0
HKD1_k127_6070091_3 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000354 112.0
HKD1_k127_6070091_4 Belongs to the frataxin family K06202 - - 0.000000000000000001465 89.0
HKD1_k127_6070091_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000044 84.0
HKD1_k127_6070513_0 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000001277 120.0
HKD1_k127_6074710_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
HKD1_k127_6076213_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009318 246.0
HKD1_k127_6076213_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006362 235.0
HKD1_k127_6076213_10 amine dehydrogenase activity - - - 0.00000001519 64.0
HKD1_k127_6076213_2 - - - - 0.00000000000000000000000000000000000000000000000005075 187.0
HKD1_k127_6076213_3 OsmC-like protein K09136 - - 0.0000000000000000000000000000000002427 142.0
HKD1_k127_6076213_4 Cytochrome c - - - 0.0000000000000000000000000000008044 126.0
HKD1_k127_6076213_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000003703 125.0
HKD1_k127_6076213_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000000000000000002614 100.0
HKD1_k127_6076213_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000003519 100.0
HKD1_k127_6076213_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000003143 81.0
HKD1_k127_6078560_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 422.0
HKD1_k127_6078560_1 helix-turn-helix domain protein - - - 0.0000000000000000000000009251 109.0
HKD1_k127_6078560_2 HNH nucleases - - - 0.000000000001458 75.0
HKD1_k127_6078560_3 Putative addiction module component - - - 0.00000000004904 66.0
HKD1_k127_6092247_0 Stigma-specific protein, Stig1 - - - 0.000000000000000000000000000002976 133.0
HKD1_k127_6092247_1 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000006725 127.0
HKD1_k127_6092247_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000002275 118.0
HKD1_k127_6092247_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000567 115.0
HKD1_k127_6092247_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000009834 96.0
HKD1_k127_6092247_5 YjbR - - - 0.00000003783 65.0
HKD1_k127_6092247_6 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0008363 50.0
HKD1_k127_6094619_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 527.0
HKD1_k127_6094619_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000002472 244.0
HKD1_k127_6094619_2 transferase activity, transferring glycosyl groups - - - 0.00004313 48.0
HKD1_k127_6100916_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
HKD1_k127_6100916_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 350.0
HKD1_k127_6100916_2 Transcription factor zinc-finger - - - 0.0000009684 56.0
HKD1_k127_6100916_3 serine threonine protein kinase - - - 0.0002922 49.0
HKD1_k127_6101200_0 TonB dependent receptor K02014 - - 5.489e-253 805.0
HKD1_k127_6101200_1 Transglycosylase K05367 - 2.4.1.129 6.822e-210 700.0
HKD1_k127_6101200_2 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 535.0
HKD1_k127_6101200_3 Glutathione S-transferase, N-terminal domain - - - 0.000002366 57.0
HKD1_k127_6101359_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000246 282.0
HKD1_k127_6101359_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000009459 198.0
HKD1_k127_6107783_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 372.0
HKD1_k127_6107783_1 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000008727 220.0
HKD1_k127_6107783_2 ASPIC and UnbV - - - 0.0000000000000000000000009169 121.0
HKD1_k127_6111508_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 547.0
HKD1_k127_6111508_1 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 426.0
HKD1_k127_6111508_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004902 250.0
HKD1_k127_6111508_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
HKD1_k127_6111508_4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
HKD1_k127_6111508_5 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001192 198.0
HKD1_k127_6111508_6 prohibitin homologues - - - 0.0000000000000000000000001652 120.0
HKD1_k127_6111508_7 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000001096 87.0
HKD1_k127_6112925_0 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000006367 152.0
HKD1_k127_6112925_1 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000005744 107.0
HKD1_k127_6112925_2 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000002477 100.0
HKD1_k127_6112925_3 Tetratricopeptide repeat - - - 0.000000000003925 72.0
HKD1_k127_6112925_4 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation K01691,K13539 - - 0.00002802 55.0
HKD1_k127_6132935_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.654e-245 777.0
HKD1_k127_6132935_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 363.0
HKD1_k127_6132935_2 Lipopolysaccharide kinase (Kdo/WaaP) family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 362.0
HKD1_k127_6132935_3 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001478 287.0
HKD1_k127_6132935_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000185 246.0
HKD1_k127_6132935_5 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000000000000000001671 169.0
HKD1_k127_6132935_7 Belongs to the ompA family K03640 - - 0.000000000000000000000000000001045 131.0
HKD1_k127_6132935_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000005515 119.0
HKD1_k127_6133338_0 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000003215 209.0
HKD1_k127_6133338_2 FHA domain - - - 0.00000000000000000000000000000001779 143.0
HKD1_k127_6134666_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 461.0
HKD1_k127_6134666_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 360.0
HKD1_k127_6134666_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 300.0
HKD1_k127_6134666_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000008657 226.0
HKD1_k127_6134666_4 aminopeptidase N - - - 0.00000000000000000000000000000003388 144.0
HKD1_k127_6134666_5 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000002051 123.0
HKD1_k127_6134666_7 Sulfatase K01133 - 3.1.6.6 0.0000000005824 68.0
HKD1_k127_6134666_8 oxidoreductase activity K07114 - - 0.0000001332 55.0
HKD1_k127_6134666_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000003749 59.0
HKD1_k127_6136190_1 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000002339 189.0
HKD1_k127_6137074_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 372.0
HKD1_k127_6137074_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000001631 207.0
HKD1_k127_6137074_2 - - - - 0.00000000000000000001332 98.0
HKD1_k127_6155487_0 Family membership - - - 9.759e-310 991.0
HKD1_k127_6155487_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 287.0
HKD1_k127_6155487_2 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001414 296.0
HKD1_k127_617065_0 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001887 259.0
HKD1_k127_617065_1 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000003449 231.0
HKD1_k127_617065_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000001462 207.0
HKD1_k127_617065_3 - - - - 0.00000000000000000003473 93.0
HKD1_k127_617065_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000006856 61.0
HKD1_k127_6173061_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 464.0
HKD1_k127_6173061_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001142 284.0
HKD1_k127_6173061_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000003514 216.0
HKD1_k127_6173061_3 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.00000000000000000000000000000007997 134.0
HKD1_k127_6173061_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001256 124.0
HKD1_k127_6173061_5 sphingolipid delta-4 desaturase activity K04712,K20028 GO:0000003,GO:0000170,GO:0000212,GO:0000226,GO:0000280,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0005789,GO:0005886,GO:0005887,GO:0006066,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006643,GO:0006665,GO:0006667,GO:0006670,GO:0006672,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007053,GO:0007140,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0008610,GO:0009055,GO:0009058,GO:0009987,GO:0010941,GO:0010942,GO:0012505,GO:0012506,GO:0016006,GO:0016020,GO:0016021,GO:0016043,GO:0016053,GO:0016192,GO:0016491,GO:0016705,GO:0019751,GO:0019752,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0022900,GO:0030141,GO:0030148,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032501,GO:0032504,GO:0032787,GO:0032940,GO:0033559,GO:0034311,GO:0034312,GO:0034641,GO:0035579,GO:0036230,GO:0042119,GO:0042175,GO:0042284,GO:0042581,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045055,GO:0045321,GO:0046165,GO:0046173,GO:0046394,GO:0046467,GO:0046512,GO:0046513,GO:0046519,GO:0046520,GO:0046903,GO:0048232,GO:0048285,GO:0048518,GO:0048522,GO:0048609,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051225,GO:0051234,GO:0051321,GO:0051704,GO:0055114,GO:0065007,GO:0070925,GO:0070938,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0090306,GO:0097164,GO:0097708,GO:0098588,GO:0098805,GO:0098827,GO:0099503,GO:0140013,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1903046 1.14.18.5,1.14.19.17,2.3.1.225 0.00000000000000000001595 104.0
HKD1_k127_6173061_6 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000001661 60.0
HKD1_k127_617365_0 Family membership - - - 3.38e-198 664.0
HKD1_k127_617365_1 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 597.0
HKD1_k127_6177419_0 AcrB/AcrD/AcrF family K03296 - - 1.333e-239 767.0
HKD1_k127_6177419_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003492 276.0
HKD1_k127_6177419_2 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000001529 224.0
HKD1_k127_6177419_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000008263 194.0
HKD1_k127_6177419_4 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000004432 162.0
HKD1_k127_6202255_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 474.0
HKD1_k127_6202255_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 424.0
HKD1_k127_6202255_2 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 363.0
HKD1_k127_6202255_4 PilZ domain - - - 0.0000000000000000001824 93.0
HKD1_k127_6202255_5 PFAM response regulator receiver K03413 - - 0.0000000000000000013 91.0
HKD1_k127_6202255_6 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000001171 86.0
HKD1_k127_6204115_0 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 431.0
HKD1_k127_6204115_1 Sterol carrier protein domain - - - 0.00000000000000002685 94.0
HKD1_k127_6204115_2 palmitoyl-(protein) hydrolase activity - - - 0.00009202 51.0
HKD1_k127_6222165_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 518.0
HKD1_k127_6222165_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 370.0
HKD1_k127_6222165_10 oxidoreductase activity - - - 0.000000000000000000000000000000000000004518 169.0
HKD1_k127_6222165_11 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000002758 145.0
HKD1_k127_6222165_13 domain protein - - - 0.0000001893 63.0
HKD1_k127_6222165_2 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 368.0
HKD1_k127_6222165_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 311.0
HKD1_k127_6222165_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001556 285.0
HKD1_k127_6222165_5 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003263 286.0
HKD1_k127_6222165_6 peptidase K19304 - - 0.0000000000000000000000000000000000000000000000000000000000000000002116 243.0
HKD1_k127_6222165_7 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
HKD1_k127_6222165_8 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
HKD1_k127_6222165_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000006301 185.0
HKD1_k127_6228217_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 446.0
HKD1_k127_6228217_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000001193 210.0
HKD1_k127_6228217_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000352 162.0
HKD1_k127_6228217_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000001517 108.0
HKD1_k127_6241205_0 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 303.0
HKD1_k127_6241205_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000005704 226.0
HKD1_k127_6241205_2 Protein conserved in bacteria K09929 - - 0.00000000000000000000000000000000004523 149.0
HKD1_k127_6241205_4 peptidyl-tyrosine sulfation - - - 0.00008974 52.0
HKD1_k127_6253473_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 351.0
HKD1_k127_6253473_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 341.0
HKD1_k127_6253473_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 327.0
HKD1_k127_6253473_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008222 278.0
HKD1_k127_6253473_4 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
HKD1_k127_6253473_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000003349 184.0
HKD1_k127_6253473_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000001027 182.0
HKD1_k127_6253473_8 oxidoreductase - - - 0.00000000000000000000000001888 114.0
HKD1_k127_6255063_0 serine threonine protein kinase - - - 6.793e-228 734.0
HKD1_k127_6255063_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 347.0
HKD1_k127_6255063_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000003905 128.0
HKD1_k127_6255063_11 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000001106 113.0
HKD1_k127_6255063_12 Protein of unknown function (DUF3224) - - - 0.00000000000000000003651 101.0
HKD1_k127_6255063_13 Hep Hag repeat protein - - - 0.000000000000000000196 98.0
HKD1_k127_6255063_14 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000007538 86.0
HKD1_k127_6255063_15 oxidoreductase activity K07114 - - 0.0000000000000009074 90.0
HKD1_k127_6255063_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000123 68.0
HKD1_k127_6255063_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000499 257.0
HKD1_k127_6255063_3 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000891 259.0
HKD1_k127_6255063_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000001822 229.0
HKD1_k127_6255063_5 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000008246 211.0
HKD1_k127_6255063_6 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000643 149.0
HKD1_k127_6255063_7 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000001426 145.0
HKD1_k127_6255063_8 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000001222 125.0
HKD1_k127_6255063_9 Histidine kinase K07709,K10942 - 2.7.13.3 0.000000000000000000000000000001416 130.0
HKD1_k127_6263020_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 592.0
HKD1_k127_6263020_1 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000002251 259.0
HKD1_k127_6263020_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000001703 208.0
HKD1_k127_6263020_3 Belongs to the P-Pant transferase superfamily K02362 - 6.3.2.14 0.00000000000000000000003205 108.0
HKD1_k127_6263020_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000001998 104.0
HKD1_k127_6263020_5 NMT1-like family K02051,K15553 - - 0.000000000000007676 88.0
HKD1_k127_6263020_6 SCO1/SenC - - - 0.000002058 59.0
HKD1_k127_6263020_7 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.0000171 48.0
HKD1_k127_6263020_8 - - - - 0.0001124 47.0
HKD1_k127_6271914_0 Periplasmic protein TonB links inner and outer membranes - - - 7.55e-237 762.0
HKD1_k127_6271914_1 oligosaccharyl transferase activity - - - 2.045e-201 652.0
HKD1_k127_6271914_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 330.0
HKD1_k127_6271914_4 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000000000000000000001351 180.0
HKD1_k127_6273266_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 461.0
HKD1_k127_6273266_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006894 287.0
HKD1_k127_6279226_0 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 370.0
HKD1_k127_6279226_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000001961 182.0
HKD1_k127_6279226_10 domain, Protein K07654 - 2.7.13.3 0.0007624 51.0
HKD1_k127_6279226_2 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000938 183.0
HKD1_k127_6279226_3 PPIC-type PPIASE domain - - - 0.0000000000000000000000001007 117.0
HKD1_k127_6279226_4 Thioredoxin-like - - - 0.00000000000000000000009957 105.0
HKD1_k127_6279226_5 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000005409 94.0
HKD1_k127_6279226_6 PPIC-type PPIASE domain - - - 0.0000000000000006815 87.0
HKD1_k127_6279226_7 COG0517 FOG CBS domain - - - 0.000000000000147 82.0
HKD1_k127_6279226_8 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000562 55.0
HKD1_k127_6279226_9 Stigma-specific protein, Stig1 - - - 0.00005744 55.0
HKD1_k127_6293373_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 482.0
HKD1_k127_6293373_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 344.0
HKD1_k127_6293373_2 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000009025 194.0
HKD1_k127_6293373_3 Response regulator, receiver K03413 - - 0.00000000000000251 80.0
HKD1_k127_6293373_4 - - - - 0.00000000001127 75.0
HKD1_k127_6297955_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
HKD1_k127_6297955_1 EB module - - - 0.000000000000000000000000000000000000000000000000000000000000003138 236.0
HKD1_k127_6297955_2 Beta-galactosidase K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000000000000000007314 233.0
HKD1_k127_6297955_3 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004466 235.0
HKD1_k127_6297955_4 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000003817 157.0
HKD1_k127_6297955_5 - - - - 0.00000000000000000001154 95.0
HKD1_k127_630210_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 296.0
HKD1_k127_630210_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003388 274.0
HKD1_k127_630210_3 - - - - 0.00001049 50.0
HKD1_k127_630210_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00002114 56.0
HKD1_k127_6308450_0 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 345.0
HKD1_k127_6308450_1 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 302.0
HKD1_k127_6308450_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000023 291.0
HKD1_k127_6308450_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001079 226.0
HKD1_k127_6308450_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000006508 203.0
HKD1_k127_6308450_5 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000001704 151.0
HKD1_k127_6308450_6 nucleotidyltransferase activity - - - 0.000000000000000000000000000000003607 138.0
HKD1_k127_6308450_7 PFAM regulatory protein TetR - - - 0.0000000000008795 81.0
HKD1_k127_6308450_8 - - - - 0.00000005374 61.0
HKD1_k127_6308450_9 Galactose oxidase, central domain - - - 0.000004703 59.0
HKD1_k127_6328475_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 351.0
HKD1_k127_6328475_1 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 344.0
HKD1_k127_6328475_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000001597 134.0
HKD1_k127_633726_0 protein kinase activity - - - 1.813e-198 635.0
HKD1_k127_633726_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
HKD1_k127_633726_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006095 261.0
HKD1_k127_633726_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000848 179.0
HKD1_k127_633726_4 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000003473 132.0
HKD1_k127_633726_5 sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000645 131.0
HKD1_k127_6343484_0 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 380.0
HKD1_k127_6343484_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 304.0
HKD1_k127_6343484_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000005254 217.0
HKD1_k127_6343484_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000009793 97.0
HKD1_k127_6343484_4 Disulphide bond corrector protein DsbC - - - 0.00000000002068 73.0
HKD1_k127_6343484_5 PilZ domain - - - 0.000000009875 63.0
HKD1_k127_6351081_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 396.0
HKD1_k127_6351081_1 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000005655 171.0
HKD1_k127_6351081_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000004009 98.0
HKD1_k127_6359845_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 371.0
HKD1_k127_6359845_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001688 232.0
HKD1_k127_6359845_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000007164 211.0
HKD1_k127_6359845_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000001563 155.0
HKD1_k127_6359845_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000002866 127.0
HKD1_k127_6359845_5 Patatin-like phospholipase - - - 0.0000000000000000000005354 104.0
HKD1_k127_6359845_6 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000004888 91.0
HKD1_k127_6359845_7 GMC oxidoreductase K03333 - 1.1.3.6 0.000000001858 61.0
HKD1_k127_6365432_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
HKD1_k127_6365432_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009932 247.0
HKD1_k127_6376997_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000001161 78.0
HKD1_k127_6378654_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 497.0
HKD1_k127_6378654_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 350.0
HKD1_k127_6378654_2 - - - - 0.0000000000000000000000000000000000000000000002852 178.0
HKD1_k127_6397702_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 2.404e-217 682.0
HKD1_k127_6397702_1 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001655 276.0
HKD1_k127_6397702_3 Belongs to the peptidase S8 family - - - 0.00000000009964 73.0
HKD1_k127_6397702_4 Chromate resistance exported protein - - - 0.0000000243 59.0
HKD1_k127_6397702_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002731 53.0
HKD1_k127_6415693_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
HKD1_k127_6415693_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005561 297.0
HKD1_k127_6415693_2 domain, Protein - - - 0.0000000000000000000000003264 107.0
HKD1_k127_641679_0 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 408.0
HKD1_k127_641679_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 356.0
HKD1_k127_641679_2 FMN binding - - - 0.00000000000000000000000000000001349 141.0
HKD1_k127_6437443_0 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 558.0
HKD1_k127_6437443_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 407.0
HKD1_k127_6437443_10 PFAM Kelch motif - - - 0.000000000000000000000000000000000000000005726 169.0
HKD1_k127_6437443_11 - - - - 0.000000000000000000000000000000000000005515 156.0
HKD1_k127_6437443_12 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000169 148.0
HKD1_k127_6437443_13 oxidoreductase activity K07114 - - 0.000000001408 69.0
HKD1_k127_6437443_2 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 394.0
HKD1_k127_6437443_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
HKD1_k127_6437443_4 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 345.0
HKD1_k127_6437443_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 339.0
HKD1_k127_6437443_6 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 336.0
HKD1_k127_6437443_7 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 333.0
HKD1_k127_6437443_8 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006502 254.0
HKD1_k127_6437443_9 - - - - 0.000000000000000000000000000000000000000000000000006167 203.0
HKD1_k127_6449367_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
HKD1_k127_6449367_1 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
HKD1_k127_6449367_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000003078 201.0
HKD1_k127_6449367_3 Carboxyltransferase domain, subdomain A and B - - - 0.00000000000000000000000000000000000000000000000006504 194.0
HKD1_k127_6449367_4 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000004198 154.0
HKD1_k127_6449367_5 COGs COG2133 Glucose sorbosone dehydrogenase - - - 0.000000000000000000000000008553 125.0
HKD1_k127_6449367_6 HicB family - - - 0.000000000000003585 81.0
HKD1_k127_6449367_7 Glucose / Sorbosone dehydrogenase - - - 0.0000000000001649 85.0
HKD1_k127_6449367_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000489 46.0
HKD1_k127_6464575_0 xanthine catabolic process K00106 GO:0000166,GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0004854,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006801,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009115,GO:0009414,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0016491,GO:0016725,GO:0016726,GO:0016903,GO:0019439,GO:0034641,GO:0036094,GO:0042221,GO:0042554,GO:0043167,GO:0043168,GO:0043546,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046110,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072523,GO:0072593,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901700 1.17.1.4,1.17.3.2 1.466e-274 893.0
HKD1_k127_6464575_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 529.0
HKD1_k127_6464575_2 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 331.0
HKD1_k127_6464575_3 PFAM VanW family protein K18346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005322 265.0
HKD1_k127_6464575_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000001122 249.0
HKD1_k127_6464575_5 adenosine 5'-monophosphoramidase activity - - - 0.00000000000000000000000000000000000006889 154.0
HKD1_k127_6464575_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000007589 132.0
HKD1_k127_6464575_7 - - - - 0.00000000003665 75.0
HKD1_k127_6464575_8 Virulence factor SrfB - - - 0.0000005599 60.0
HKD1_k127_6468670_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001844 295.0
HKD1_k127_6468670_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
HKD1_k127_6468670_2 - - - - 0.0000008939 57.0
HKD1_k127_6468670_3 - - - - 0.0000235 53.0
HKD1_k127_648192_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 313.0
HKD1_k127_648192_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008424 262.0
HKD1_k127_648192_2 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.0000000000000000000000000000000000000000000000000000000000001477 233.0
HKD1_k127_648192_3 Phospholipase/Carboxylesterase - - - 0.0000000004383 72.0
HKD1_k127_6503200_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 389.0
HKD1_k127_6503200_2 protein kinase activity - - - 0.0001084 52.0
HKD1_k127_65059_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1209.0
HKD1_k127_65059_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 577.0
HKD1_k127_6507563_0 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 450.0
HKD1_k127_6507563_1 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004567 307.0
HKD1_k127_6507563_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009562 225.0
HKD1_k127_6507563_3 peptidase - - - 0.00000000000209 78.0
HKD1_k127_6507563_4 energy transducer activity - - - 0.0000000004075 70.0
HKD1_k127_6508271_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 334.0
HKD1_k127_6508271_1 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000001309 160.0
HKD1_k127_6508271_2 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000005902 101.0
HKD1_k127_6519944_0 Sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 368.0
HKD1_k127_6519944_1 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 295.0
HKD1_k127_6519944_2 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
HKD1_k127_6519944_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000001242 213.0
HKD1_k127_6519944_5 Protease prsW family - - - 0.00000000000000000000000000000000000000008492 157.0
HKD1_k127_6519944_6 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000976 71.0
HKD1_k127_6536161_0 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 362.0
HKD1_k127_6536161_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000001026 182.0
HKD1_k127_6536161_2 alpha beta - - - 0.000000000000000000000000006107 113.0
HKD1_k127_6544222_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.4e-222 723.0
HKD1_k127_6544222_1 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 397.0
HKD1_k127_6544222_10 2TM domain - - - 0.0000000000000008453 84.0
HKD1_k127_6544222_12 Transcriptional regulator - - - 0.000000418 53.0
HKD1_k127_6544222_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 313.0
HKD1_k127_6544222_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008651 269.0
HKD1_k127_6544222_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
HKD1_k127_6544222_6 - - - - 0.0000000000000000000000000000000000001071 151.0
HKD1_k127_6544222_8 Hep Hag repeat protein - - - 0.0000000000000000329 92.0
HKD1_k127_6544222_9 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000003639 90.0
HKD1_k127_6544323_0 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 553.0
HKD1_k127_6544323_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 456.0
HKD1_k127_6544323_2 - - - - 0.000000000000000000000000001782 131.0
HKD1_k127_6544323_3 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000001626 100.0
HKD1_k127_654550_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 447.0
HKD1_k127_654550_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 381.0
HKD1_k127_654550_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 329.0
HKD1_k127_654550_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 256.0
HKD1_k127_654550_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000002129 119.0
HKD1_k127_654550_6 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000002499 91.0
HKD1_k127_6551145_0 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 332.0
HKD1_k127_6551145_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000001019 226.0
HKD1_k127_6551145_2 peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000088 206.0
HKD1_k127_6551145_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006348 201.0
HKD1_k127_6551145_4 Transposase K07496 - - 0.000000000001169 72.0
HKD1_k127_6551145_5 Beta-L-arabinofuranosidase, GH127 - - - 0.000000002147 71.0
HKD1_k127_6557288_0 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 609.0
HKD1_k127_6557288_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
HKD1_k127_6557288_10 YXWGXW repeat (2 copies) - - - 0.00000109 58.0
HKD1_k127_6557288_11 gluconolactonase activity - - - 0.00004456 55.0
HKD1_k127_6557288_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 423.0
HKD1_k127_6557288_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 382.0
HKD1_k127_6557288_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 376.0
HKD1_k127_6557288_5 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007317 255.0
HKD1_k127_6557288_6 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001533 254.0
HKD1_k127_6557288_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000006331 235.0
HKD1_k127_6557288_8 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000002573 151.0
HKD1_k127_6557288_9 protein ADP-ribosylase activity K10798 GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007568,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008340,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010259,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251 2.4.2.30 0.0000001584 60.0
HKD1_k127_6566143_0 Tetratricopeptide repeat - - - 2.961e-257 803.0
HKD1_k127_6566143_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HKD1_k127_6566143_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
HKD1_k127_6566143_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000005798 194.0
HKD1_k127_6566143_5 HEAT repeats - - - 0.00000000000000000000000000000000000000000001294 183.0
HKD1_k127_6566143_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000007047 166.0
HKD1_k127_6566143_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001447 119.0
HKD1_k127_6566143_9 nuclease activity K07460 - - 0.000000000000000000001055 100.0
HKD1_k127_6568363_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 334.0
HKD1_k127_6568363_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000004146 260.0
HKD1_k127_6568363_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000006504 184.0
HKD1_k127_6568363_3 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000001277 105.0
HKD1_k127_6568363_4 Domain of unknown function (DUF362) - - - 0.0000000000002261 84.0
HKD1_k127_6568363_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000005656 66.0
HKD1_k127_6606600_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 311.0
HKD1_k127_6606600_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000002244 166.0
HKD1_k127_6606600_2 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000008133 98.0
HKD1_k127_6606600_3 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000002865 67.0
HKD1_k127_6606600_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000904 54.0
HKD1_k127_6609034_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 2.629e-250 790.0
HKD1_k127_6609034_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 407.0
HKD1_k127_6609034_2 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 343.0
HKD1_k127_6609034_3 PFAM Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 256.0
HKD1_k127_6609034_4 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000009148 267.0
HKD1_k127_6609034_5 Macro domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
HKD1_k127_6610290_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 392.0
HKD1_k127_6610290_1 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000003695 149.0
HKD1_k127_6610290_2 COG1073 hydrolases of the alpha beta superfamily - - - 0.0000000000000005535 93.0
HKD1_k127_6621368_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 1.001e-249 784.0
HKD1_k127_6621368_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 374.0
HKD1_k127_6621368_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002028 260.0
HKD1_k127_6621368_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000006969 219.0
HKD1_k127_6621368_4 - - - - 0.0000000000000000000000000000000000000000000000003238 184.0
HKD1_k127_6621368_5 - - - - 0.00000000000000000000000000000003716 143.0
HKD1_k127_6624654_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 342.0
HKD1_k127_6624654_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 302.0
HKD1_k127_6624654_2 - - - - 0.00000000000000000000000000000000000000000001492 166.0
HKD1_k127_6624654_3 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.00000000000000000000000000000000002975 145.0
HKD1_k127_6624654_4 Extensin-like protein C-terminus - - - 0.000000000000000000000000000001382 130.0
HKD1_k127_6624654_5 Stigma-specific protein, Stig1 - - - 0.000000000000000000000000001413 129.0
HKD1_k127_6624654_7 Beta-L-arabinofuranosidase, GH127 - - - 0.000000002694 66.0
HKD1_k127_6624654_8 PBS lyase HEAT-like repeat - - - 0.00002103 58.0
HKD1_k127_6639150_0 SCP-2 sterol transfer family - - - 2.207e-309 967.0
HKD1_k127_6639997_0 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
HKD1_k127_6639997_2 general secretion pathway protein K02456,K02650 - - 0.00000000000000000007159 99.0
HKD1_k127_6639997_3 Prokaryotic N-terminal methylation motif K02457 - - 0.00001663 51.0
HKD1_k127_6651303_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.685e-207 659.0
HKD1_k127_6651303_1 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000000000000000000000000003238 162.0
HKD1_k127_6651303_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K00558,K07457,K10773 - 2.1.1.37,4.2.99.18 0.0000000001092 75.0
HKD1_k127_6651303_5 Cysteine-rich secretory protein family - - - 0.00007082 53.0
HKD1_k127_6651652_0 Bacterial-like globin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 379.0
HKD1_k127_6651652_1 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 343.0
HKD1_k127_6651652_10 domain, Protein - - - 0.00000000003132 74.0
HKD1_k127_6651652_11 - - - - 0.00009334 56.0
HKD1_k127_6651652_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 326.0
HKD1_k127_6651652_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009879 260.0
HKD1_k127_6651652_4 transcription factor binding - - - 0.00000000000000000000000000000000000000000000001835 173.0
HKD1_k127_6651652_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000006566 157.0
HKD1_k127_6651652_6 - - - - 0.000000000000000000000000000000009958 132.0
HKD1_k127_6651652_7 GTP binding K06883 - - 0.00000000000000000000000000000001841 147.0
HKD1_k127_6651652_8 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000002942 126.0
HKD1_k127_6651652_9 - - - - 0.00000000000002883 85.0
HKD1_k127_6653657_0 AMP-binding enzyme - - - 2.819e-223 715.0
HKD1_k127_6653657_1 DUF1704 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 604.0
HKD1_k127_6653657_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000008802 219.0
HKD1_k127_6653657_11 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000000000234 158.0
HKD1_k127_6653657_12 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000000000002622 161.0
HKD1_k127_6653657_14 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000002932 112.0
HKD1_k127_6653657_16 Protein of unknown function (DUF3501) - - - 0.00000000000000000000001245 117.0
HKD1_k127_6653657_17 Universal stress protein family - - - 0.000000000000000001326 99.0
HKD1_k127_6653657_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000004156 71.0
HKD1_k127_6653657_2 Cysteine-rich domain K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 550.0
HKD1_k127_6653657_20 phosphorelay signal transduction system - - - 0.0000000007546 63.0
HKD1_k127_6653657_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 448.0
HKD1_k127_6653657_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 393.0
HKD1_k127_6653657_5 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
HKD1_k127_6653657_6 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 318.0
HKD1_k127_6653657_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 302.0
HKD1_k127_6653657_8 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000002183 248.0
HKD1_k127_6653657_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000006386 230.0
HKD1_k127_6655443_0 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001163 290.0
HKD1_k127_6655443_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005765 257.0
HKD1_k127_6655443_2 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000001999 188.0
HKD1_k127_6655443_3 Pectic acid lyase - - - 0.000000000000000000000000000000009968 141.0
HKD1_k127_6665753_0 Protein-arginine deiminase (PAD) middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 506.0
HKD1_k127_6665753_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 430.0
HKD1_k127_6665753_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 313.0
HKD1_k127_6665753_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000001009 151.0
HKD1_k127_6665753_5 Family membership - - - 0.0000000000006296 78.0
HKD1_k127_6672975_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 492.0
HKD1_k127_6672975_1 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 422.0
HKD1_k127_6672975_2 phosphate ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000003233 248.0
HKD1_k127_6672975_3 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000002939 233.0
HKD1_k127_6672975_5 ExbD TolR K03559 - - 0.00000000000000000000000000000000000000005571 164.0
HKD1_k127_6672975_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000004496 84.0
HKD1_k127_6676332_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 8.226e-250 795.0
HKD1_k127_6676332_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 440.0
HKD1_k127_6676332_2 Iron-sulfur cluster-binding domain K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 341.0
HKD1_k127_6676332_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008724 274.0
HKD1_k127_6676332_4 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000009706 244.0
HKD1_k127_6676332_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000001117 197.0
HKD1_k127_6676332_6 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000229 143.0
HKD1_k127_6676332_7 hemerythrin HHE cation binding domain - - - 0.000004995 60.0
HKD1_k127_6681155_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
HKD1_k127_6681155_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 319.0
HKD1_k127_6681155_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000008385 262.0
HKD1_k127_6681155_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002388 264.0
HKD1_k127_6681155_4 YjbR - - - 0.00000000000000000000000000000000001554 139.0
HKD1_k127_6681155_5 - - - - 0.00000000000000000000008021 114.0
HKD1_k127_6681155_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000004778 96.0
HKD1_k127_6681155_7 - - - - 0.00000000000751 70.0
HKD1_k127_6681155_8 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000004882 66.0
HKD1_k127_6681155_9 - - - - 0.0002882 52.0
HKD1_k127_6683062_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
HKD1_k127_6683062_1 AAA domain - - - 0.000000000000000000000000000000000000793 149.0
HKD1_k127_6683062_2 - - - - 0.000000000000000000000000000000000005676 145.0
HKD1_k127_6683062_3 Bacterial Ig-like domain 2 K08643,K12373,K13730,K15481 - 3.2.1.52 0.000002831 59.0
HKD1_k127_6686109_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.388e-218 683.0
HKD1_k127_6686109_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 412.0
HKD1_k127_6686109_2 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000009549 184.0
HKD1_k127_6686109_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001428 126.0
HKD1_k127_6688950_0 Tetratricopeptide repeat - - - 1.037e-275 882.0
HKD1_k127_6688950_1 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009014 243.0
HKD1_k127_6688950_2 spore germination - - - 0.0000000000000000000000000000000000000000000003605 178.0
HKD1_k127_6688950_3 peptidyl-tyrosine sulfation - - - 0.00000000000000005692 88.0
HKD1_k127_6688950_4 Nitroreductase family - - - 0.000000000007651 68.0
HKD1_k127_6688950_6 COG1886 Flagellar motor switch type III secretory pathway protein K02416,K03225 - - 0.0000002306 63.0
HKD1_k127_6689340_0 4Fe-4S dicluster domain K00184 - - 1.282e-250 804.0
HKD1_k127_6689340_1 Polysulphide reductase, NrfD K00185 - - 1.896e-209 660.0
HKD1_k127_6689340_2 zinc ion transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001082 272.0
HKD1_k127_6689340_3 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000984 229.0
HKD1_k127_6689340_4 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000007973 189.0
HKD1_k127_6689340_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000001864 181.0
HKD1_k127_6689340_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000003652 62.0
HKD1_k127_6704209_0 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000003159 219.0
HKD1_k127_6704209_1 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000002355 207.0
HKD1_k127_6706702_0 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 503.0
HKD1_k127_6706702_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000002665 252.0
HKD1_k127_6706702_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000001827 216.0
HKD1_k127_6706702_4 palmitoyl-(protein) hydrolase activity - - - 0.0000001242 63.0
HKD1_k127_6716467_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 601.0
HKD1_k127_6716467_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005222 239.0
HKD1_k127_6735950_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 322.0
HKD1_k127_6735950_1 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000005257 75.0
HKD1_k127_6745037_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002869 281.0
HKD1_k127_6745037_2 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000000000000000000000000000000000000003425 217.0
HKD1_k127_6745037_3 L11 methyltransferase - - - 0.000000000000000000000000000000001197 149.0
HKD1_k127_6745037_4 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000629 93.0
HKD1_k127_6745037_5 cell envelope organization K05807,K08309 - - 0.000000000000000001361 98.0
HKD1_k127_6748841_0 Two component regulator propeller - - - 5.155e-233 740.0
HKD1_k127_6748841_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005235 266.0
HKD1_k127_6748841_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000731 122.0
HKD1_k127_6749056_0 ABC transporter K02056,K05776,K10441,K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 494.0
HKD1_k127_6749056_1 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 396.0
HKD1_k127_6749056_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 362.0
HKD1_k127_6749056_3 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 299.0
HKD1_k127_6749056_4 Metallo-beta-lactamase superfamily - - - 0.000000000001342 80.0
HKD1_k127_6749056_5 - - - - 0.00003074 57.0
HKD1_k127_6749056_6 cellulose binding - - - 0.0004191 52.0
HKD1_k127_6749056_7 Has antibacterial activity - GO:0000270,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016192,GO:0016787,GO:0016798,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0061783,GO:0071704,GO:0097708,GO:0098542,GO:0098657,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0009532 50.0
HKD1_k127_6754336_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 602.0
HKD1_k127_6754336_1 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 394.0
HKD1_k127_6754336_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000002193 233.0
HKD1_k127_6761237_0 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 416.0
HKD1_k127_6761237_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 372.0
HKD1_k127_6761237_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005399 275.0
HKD1_k127_6765498_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 5.068e-212 667.0
HKD1_k127_6765498_1 Malate synthase K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 535.0
HKD1_k127_6765498_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 355.0
HKD1_k127_6765498_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 343.0
HKD1_k127_6765498_4 - - - - 0.0000000000000000000000000000000000000000007377 165.0
HKD1_k127_67680_0 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 475.0
HKD1_k127_67680_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000056 178.0
HKD1_k127_6796102_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 355.0
HKD1_k127_6796102_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
HKD1_k127_6796102_2 Belongs to the BolA IbaG family - - - 0.00000000000000007926 82.0
HKD1_k127_6796503_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 314.0
HKD1_k127_6796503_1 Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 327.0
HKD1_k127_6796503_2 ECF sigma factor K03088 - - 0.0000000000000000002823 94.0
HKD1_k127_6796503_3 Esterase PHB depolymerase - - - 0.00000000000002689 82.0
HKD1_k127_6803609_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 311.0
HKD1_k127_6803609_1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 259.0
HKD1_k127_6803609_4 belongs to the sigma-70 factor family K03088 - - 0.000213 46.0
HKD1_k127_6803609_5 Photosynthesis system II assembly factor YCF48 - - - 0.0007227 54.0
HKD1_k127_6803609_6 FHA domain - - - 0.0009183 48.0
HKD1_k127_6813874_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000002321 102.0
HKD1_k127_6813874_1 gluconolactonase activity - - - 0.0002138 50.0
HKD1_k127_6818296_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1362.0
HKD1_k127_6818296_1 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.037e-195 615.0
HKD1_k127_6818296_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 479.0
HKD1_k127_6818296_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 426.0
HKD1_k127_6818296_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002101 264.0
HKD1_k127_6818296_5 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.000000000000000000000000000003765 139.0
HKD1_k127_681898_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.004e-242 754.0
HKD1_k127_681898_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
HKD1_k127_681898_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
HKD1_k127_681898_3 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000002478 153.0
HKD1_k127_681898_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000638 121.0
HKD1_k127_681898_5 HD domain - - - 0.000000000000000000000077 98.0
HKD1_k127_6825020_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 409.0
HKD1_k127_6825020_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000001992 223.0
HKD1_k127_6825020_2 - - - - 0.000000000000000000000000000000000000000000000008061 182.0
HKD1_k127_6825020_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000001447 136.0
HKD1_k127_6825020_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000003391 103.0
HKD1_k127_6825020_5 Polymer-forming cytoskeletal - - - 0.0000000000000000002071 94.0
HKD1_k127_6850553_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000007017 120.0
HKD1_k127_6850553_1 General secretion pathway protein G K02456 - - 0.0001514 48.0
HKD1_k127_6850553_2 Mechanosensitive ion channel - - - 0.0006651 43.0
HKD1_k127_6850553_3 Domain of unknown function (DUF4974) K07165 - - 0.000833 52.0
HKD1_k127_6862660_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.871e-206 657.0
HKD1_k127_6862660_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000001736 233.0
HKD1_k127_6862660_2 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000004283 96.0
HKD1_k127_6862660_3 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000602 90.0
HKD1_k127_6862660_4 Immunity protein 27 - - - 0.00000000000006698 75.0
HKD1_k127_6862660_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000000001648 73.0
HKD1_k127_6862660_6 Evidence 5 No homology to any previously reported sequences - - - 0.0004488 47.0
HKD1_k127_6875536_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 411.0
HKD1_k127_6875536_1 amino acid ABC transporter, ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 388.0
HKD1_k127_6875536_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 357.0
HKD1_k127_6875536_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003429 263.0
HKD1_k127_6875536_4 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005963 263.0
HKD1_k127_6875536_5 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000236 250.0
HKD1_k127_6875536_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000331 94.0
HKD1_k127_6875536_7 with the alpha beta hydrolase fold - - - 0.000000000000002919 89.0
HKD1_k127_6875536_8 Peptidoglycan-binding domain 1 protein - - - 0.0000000007026 70.0
HKD1_k127_6875536_9 - - - - 0.0000001193 64.0
HKD1_k127_6879781_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.07e-319 997.0
HKD1_k127_6879781_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008337 302.0
HKD1_k127_6899489_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 316.0
HKD1_k127_6899489_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002557 259.0
HKD1_k127_6899489_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000004607 199.0
HKD1_k127_6899489_3 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000007576 181.0
HKD1_k127_6899489_4 IgGFc binding protein - - - 0.0000000000000000000000000000000000006373 142.0
HKD1_k127_6906615_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.363e-301 942.0
HKD1_k127_6906615_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.323e-220 699.0
HKD1_k127_6906615_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 604.0
HKD1_k127_6906615_3 Urease, gamma subunit K01430,K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 306.0
HKD1_k127_6906615_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000001828 214.0
HKD1_k127_6906615_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000638 211.0
HKD1_k127_6906615_6 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000001483 88.0
HKD1_k127_6906615_7 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000002505 77.0
HKD1_k127_6914028_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 451.0
HKD1_k127_6914028_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 344.0
HKD1_k127_6914028_2 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001921 274.0
HKD1_k127_6914028_3 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000125 252.0
HKD1_k127_6914028_4 acid phosphatase activity K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000006177 196.0
HKD1_k127_6914028_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000002056 173.0
HKD1_k127_6914028_6 FHA domain - - - 0.000007242 57.0
HKD1_k127_6914028_7 COG3509 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.0000691 53.0
HKD1_k127_6914028_8 Thioredoxin K05838 - - 0.00007611 56.0
HKD1_k127_6914028_9 tetratricopeptide repeat - - - 0.0001321 55.0
HKD1_k127_6923677_0 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000519 262.0
HKD1_k127_6923677_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000002183 203.0
HKD1_k127_6923677_2 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000001974 188.0
HKD1_k127_6923677_3 - - - - 0.00000000000000000000000000000000003412 139.0
HKD1_k127_6923677_5 Protein of unknown function (DUF2505) - - - 0.0000000000000000000000007735 122.0
HKD1_k127_6925066_0 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
HKD1_k127_6925066_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 304.0
HKD1_k127_6925066_2 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000085 273.0
HKD1_k127_6925066_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000008018 205.0
HKD1_k127_6925066_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000002644 161.0
HKD1_k127_6925066_6 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000001137 145.0
HKD1_k127_6925066_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000002208 153.0
HKD1_k127_6925066_8 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000002081 147.0
HKD1_k127_6949719_0 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000002432 221.0
HKD1_k127_6949719_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000002884 191.0
HKD1_k127_6949719_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000002111 164.0
HKD1_k127_6949719_4 Cation efflux family K16264 - - 0.0000000000000000000000000002391 122.0
HKD1_k127_6949719_5 unfolded protein binding K06142 - - 0.0000000000000000000000000005255 120.0
HKD1_k127_6955369_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000003801 196.0
HKD1_k127_6960639_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 422.0
HKD1_k127_6960639_1 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
HKD1_k127_6960639_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004915 196.0
HKD1_k127_6960639_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000001516 150.0
HKD1_k127_6960639_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000001141 138.0
HKD1_k127_6967021_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 2.281e-307 960.0
HKD1_k127_6967021_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 293.0
HKD1_k127_6967021_10 Domain of unknown function (DUF4142) K08995 - - 0.0000000002014 71.0
HKD1_k127_6967021_3 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000016 177.0
HKD1_k127_6967021_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000002414 142.0
HKD1_k127_6967021_5 Dienelactone hydrolase family K07020 - - 0.000000000000000000000000002514 117.0
HKD1_k127_6967021_6 - - - - 0.000000000000000000000000004056 122.0
HKD1_k127_6967021_7 synthase homocitrate synthase family - - - 0.00000000000000000302 85.0
HKD1_k127_6967021_8 - - - - 0.00000000000000001245 95.0
HKD1_k127_6967021_9 Transcriptional regulator - - - 0.00000000004012 66.0
HKD1_k127_6972268_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 440.0
HKD1_k127_6972268_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 411.0
HKD1_k127_6972268_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000001356 164.0
HKD1_k127_69730_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 409.0
HKD1_k127_69730_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005343 231.0
HKD1_k127_69730_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000001071 196.0
HKD1_k127_69730_3 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000021 157.0
HKD1_k127_69730_4 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000002217 130.0
HKD1_k127_6979938_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 350.0
HKD1_k127_6979938_1 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 331.0
HKD1_k127_6979938_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000003536 122.0
HKD1_k127_6979938_3 protein conserved in cyanobacteria - - - 0.0000000007448 61.0
HKD1_k127_6983492_0 repeat protein - - - 0.0 2681.0
HKD1_k127_6987234_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.33e-278 866.0
HKD1_k127_6987234_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.483e-256 803.0
HKD1_k127_6987234_10 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000005177 201.0
HKD1_k127_6987234_11 Bacterial PH domain - - - 0.0000000000000000000000000002905 120.0
HKD1_k127_6987234_12 Pfam:RRM_6 - - - 0.00000000000000000000000000581 117.0
HKD1_k127_6987234_13 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000001373 113.0
HKD1_k127_6987234_14 High potential iron-sulfur protein - - - 0.000000000000000003736 89.0
HKD1_k127_6987234_15 WD40 repeats - - - 0.00000000000001448 84.0
HKD1_k127_6987234_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 497.0
HKD1_k127_6987234_3 Fe-S oxidoreductases K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 464.0
HKD1_k127_6987234_4 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 325.0
HKD1_k127_6987234_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 289.0
HKD1_k127_6987234_7 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000002136 236.0
HKD1_k127_6987234_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000004804 235.0
HKD1_k127_6987234_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000002121 216.0
HKD1_k127_6988823_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.717e-272 847.0
HKD1_k127_6988823_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 376.0
HKD1_k127_6988823_2 Type III secretion protein K03230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001635 278.0
HKD1_k127_6988823_4 membrane K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000007928 241.0
HKD1_k127_6988823_5 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000005074 194.0
HKD1_k127_6988823_6 radical SAM domain protein - - - 0.00000000000000000000000000000001373 129.0
HKD1_k127_6988823_7 Thioredoxin-like - - - 0.000000000000000000004874 109.0
HKD1_k127_6988823_8 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000008857 91.0
HKD1_k127_6993828_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 483.0
HKD1_k127_6993828_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001111 260.0
HKD1_k127_6993828_2 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000002858 118.0
HKD1_k127_6999704_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005241 188.0
HKD1_k127_6999704_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000003727 79.0
HKD1_k127_6999704_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000001371 79.0
HKD1_k127_6999704_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00009191 54.0
HKD1_k127_7013297_0 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 306.0
HKD1_k127_7013297_1 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000003187 135.0
HKD1_k127_7013297_2 mRNA binding - - - 0.000000000000000000001582 102.0
HKD1_k127_7013297_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000006926 102.0
HKD1_k127_7013297_4 Transcriptional regulatory protein, C terminal - - - 0.0000000851 61.0
HKD1_k127_7013297_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000006259 63.0
HKD1_k127_7023946_0 ABC transporter K06158 - - 7.902e-203 640.0
HKD1_k127_7023946_1 - - - - 0.000000000000000000000000000000000000000000000000000797 201.0
HKD1_k127_7023946_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000004529 181.0
HKD1_k127_7024174_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 535.0
HKD1_k127_7024174_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 296.0
HKD1_k127_7029429_0 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002332 271.0
HKD1_k127_7029429_1 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
HKD1_k127_7029429_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000002294 174.0
HKD1_k127_7029429_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000002818 151.0
HKD1_k127_7029429_4 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000004184 130.0
HKD1_k127_7029429_6 phosphorelay signal transduction system K01338 - 3.4.21.53 0.0000168 55.0
HKD1_k127_7039388_0 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000002129 235.0
HKD1_k127_7039388_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000002098 179.0
HKD1_k127_7039388_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000001219 157.0
HKD1_k127_7039388_3 Thiamine biosynthesis K03154 - - 0.0000000000000000006486 87.0
HKD1_k127_7039388_4 Response regulator receiver domain - - - 0.0000000006096 66.0
HKD1_k127_7047570_0 AAA C-terminal domain K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 554.0
HKD1_k127_7047570_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 304.0
HKD1_k127_7047570_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001821 259.0
HKD1_k127_7047570_3 Tetratricopeptide repeat - - - 0.000000000000000000000000002285 123.0
HKD1_k127_7076218_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.281e-304 947.0
HKD1_k127_7076218_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 593.0
HKD1_k127_7076218_2 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 309.0
HKD1_k127_7076218_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003 268.0
HKD1_k127_7076218_4 - - - - 0.000000000000000000000000000000000000001374 148.0
HKD1_k127_7076218_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000006115 145.0
HKD1_k127_7076218_6 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005576,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000305 86.0
HKD1_k127_707813_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 385.0
HKD1_k127_707813_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000009418 241.0
HKD1_k127_707813_2 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
HKD1_k127_707813_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000001929 208.0
HKD1_k127_707813_4 Family membership K08884 - 2.7.11.1 0.00000000007249 67.0
HKD1_k127_707813_5 mevalonate kinase K00869 - 2.7.1.36 0.00000004005 59.0
HKD1_k127_7085019_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 577.0
HKD1_k127_7085019_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 528.0
HKD1_k127_7085019_10 type IV pilus secretin PilQ K02666 - - 0.00000000000000009185 95.0
HKD1_k127_7085019_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000001254 70.0
HKD1_k127_7085019_12 Fibronectin type 3 domain - - - 0.000000003758 65.0
HKD1_k127_7085019_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 429.0
HKD1_k127_7085019_4 COG0382 4-hydroxybenzoate polyprenyltransferase and related K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000002042 240.0
HKD1_k127_7085019_5 PFAM amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000002079 200.0
HKD1_k127_7085019_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000001963 182.0
HKD1_k127_7085019_8 - - - - 0.00000000000000000000000000000001495 136.0
HKD1_k127_7085019_9 - - - - 0.00000000000000000000000000002636 133.0
HKD1_k127_7087151_0 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000006905 171.0
HKD1_k127_7105762_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 318.0
HKD1_k127_7107493_0 Sulfatase - - - 1.732e-219 713.0
HKD1_k127_7107493_1 PQQ enzyme repeat K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 402.0
HKD1_k127_7107493_2 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 351.0
HKD1_k127_7107493_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000005113 209.0
HKD1_k127_7107493_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000003013 203.0
HKD1_k127_7107493_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003967 186.0
HKD1_k127_7107493_8 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000005442 109.0
HKD1_k127_7108241_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 618.0
HKD1_k127_7108241_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 504.0
HKD1_k127_7108241_2 - - - - 0.000000000242 71.0
HKD1_k127_7114657_0 response regulator K02481,K07713 - - 1.99e-206 666.0
HKD1_k127_7114657_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 448.0
HKD1_k127_7114657_10 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000001528 134.0
HKD1_k127_7114657_11 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000001786 137.0
HKD1_k127_7114657_12 Belongs to the UPF0149 family K07039 - - 0.0000000000000005403 91.0
HKD1_k127_7114657_13 Bifunctional nuclease K08999 - - 0.00000000000001811 86.0
HKD1_k127_7114657_14 - - - - 0.00002969 55.0
HKD1_k127_7114657_2 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 307.0
HKD1_k127_7114657_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001935 246.0
HKD1_k127_7114657_4 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000000000000000003001 214.0
HKD1_k127_7114657_5 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000000008717 197.0
HKD1_k127_7114657_6 Cytochrome c K00406 - - 0.00000000000000000000000000000000000000000000000002979 186.0
HKD1_k127_7114657_7 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464 - 0.00000000000000000000000000000000000000000846 162.0
HKD1_k127_7114657_8 biogenesis protein K09792 - - 0.00000000000000000000000000000000000000002648 161.0
HKD1_k127_7114657_9 TIGRFAM molybdate ABC transporter, inner membrane subunit K02018 - - 0.00000000000000000000000000000000002922 151.0
HKD1_k127_7122925_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 382.0
HKD1_k127_7122925_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000001983 187.0
HKD1_k127_7122925_2 Domain of unknown function (DU1801) - - - 0.000000000000000000006024 96.0
HKD1_k127_7122925_3 Domain of unknown function (DUF4132) - - - 0.00000000000000000001486 107.0
HKD1_k127_7122925_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000001997 94.0
HKD1_k127_7122925_5 Kelch-like family member 13 K10447 GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010564,GO:0016567,GO:0019538,GO:0030496,GO:0031461,GO:0031463,GO:0032446,GO:0032465,GO:0032991,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051302,GO:0051726,GO:0065007,GO:0070647,GO:0071704,GO:1901564,GO:1902494,GO:1990234 - 0.00001341 57.0
HKD1_k127_7131371_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
HKD1_k127_7131371_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003157 282.0
HKD1_k127_7131371_2 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000002359 74.0
HKD1_k127_7131371_3 Domain of unknown function (DUF4388) - - - 0.00000000001048 75.0
HKD1_k127_7134857_0 PD-(D/E)XK nuclease superfamily - - - 0.0 1047.0
HKD1_k127_7134857_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 331.0
HKD1_k127_7134857_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000002496 198.0
HKD1_k127_7134857_3 Protein conserved in bacteria - - - 0.00000000000000000002059 98.0
HKD1_k127_7136196_0 Belongs to the CarB family K01955 - 6.3.5.5 1.013e-239 758.0
HKD1_k127_7136196_1 Transglycosylase SLT domain K08306,K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 389.0
HKD1_k127_7169120_0 4Fe-4S single cluster domain K06937 - - 6.446e-273 863.0
HKD1_k127_7169120_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 384.0
HKD1_k127_7169120_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000004354 224.0
HKD1_k127_7169120_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00002055 55.0
HKD1_k127_7171274_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 469.0
HKD1_k127_7171274_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 430.0
HKD1_k127_7171274_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 409.0
HKD1_k127_7171274_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 331.0
HKD1_k127_7171274_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
HKD1_k127_7171274_5 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000005046 224.0
HKD1_k127_7171274_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000121 212.0
HKD1_k127_7171274_7 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000007964 196.0
HKD1_k127_7171274_8 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000007271 124.0
HKD1_k127_7171274_9 DSBA-like thioredoxin domain - - - 0.0000000108 56.0
HKD1_k127_7173104_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 443.0
HKD1_k127_7173104_1 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 325.0
HKD1_k127_7173104_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000007953 123.0
HKD1_k127_7186061_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 380.0
HKD1_k127_7186061_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000224 289.0
HKD1_k127_7186061_2 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
HKD1_k127_7186061_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000004123 171.0
HKD1_k127_7186061_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000000000000001043 156.0
HKD1_k127_7193743_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 404.0
HKD1_k127_7193743_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 342.0
HKD1_k127_7193743_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000003527 231.0
HKD1_k127_7193743_3 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000107 193.0
HKD1_k127_7193743_4 Endoribonuclease L-PSP K04782 - 4.2.99.21 0.0000000000000000000000000000000000000003045 172.0
HKD1_k127_7193743_5 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.00000000000000000000000000000000000002962 157.0
HKD1_k127_7193743_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000006495 121.0
HKD1_k127_7193743_7 Family membership K08884,K12132 - 2.7.11.1 0.0000001014 61.0
HKD1_k127_7196753_0 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 493.0
HKD1_k127_7196753_1 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 421.0
HKD1_k127_7196753_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000001993 220.0
HKD1_k127_7196753_11 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000001521 225.0
HKD1_k127_7196753_12 PFAM Oxidoreductase K18855 - 1.1.1.374 0.000000000000000000000000000000000000000002966 177.0
HKD1_k127_7196753_13 Glycosyl transferase family 2 - - - 0.000000000000000000000000000002984 134.0
HKD1_k127_7196753_14 O-acyltransferase activity - - - 0.0000000000000000000000001742 121.0
HKD1_k127_7196753_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 414.0
HKD1_k127_7196753_3 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 392.0
HKD1_k127_7196753_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 383.0
HKD1_k127_7196753_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 339.0
HKD1_k127_7196753_6 Epimerase dehydratase K19180 - 1.1.1.339 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 292.0
HKD1_k127_7196753_7 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000952 286.0
HKD1_k127_7196753_8 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 275.0
HKD1_k127_7196753_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001443 247.0
HKD1_k127_7197168_0 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 424.0
HKD1_k127_7197168_1 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 358.0
HKD1_k127_7197168_10 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0000000000000000000001808 105.0
HKD1_k127_7197168_11 Stigma-specific protein, Stig1 - - - 0.0000000000000000000002232 109.0
HKD1_k127_7197168_13 zinc-ribbon domain - - - 0.000003301 55.0
HKD1_k127_7197168_2 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 333.0
HKD1_k127_7197168_3 PFAM Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
HKD1_k127_7197168_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000692 216.0
HKD1_k127_7197168_6 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000001667 208.0
HKD1_k127_7197168_9 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000003278 120.0
HKD1_k127_7201328_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.717e-246 773.0
HKD1_k127_7201328_1 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 547.0
HKD1_k127_7201328_2 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 332.0
HKD1_k127_7201328_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000352 164.0
HKD1_k127_7201328_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000001136 157.0
HKD1_k127_7201328_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000005574 139.0
HKD1_k127_7201328_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000002603 115.0
HKD1_k127_7201328_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000001695 87.0
HKD1_k127_7207671_0 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 387.0
HKD1_k127_7207671_1 - - - - 0.0000000000000000000000000000000000000000001005 166.0
HKD1_k127_7231114_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 424.0
HKD1_k127_7231114_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000479 179.0
HKD1_k127_7231114_2 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001479 160.0
HKD1_k127_7231114_3 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000006899 149.0
HKD1_k127_7231114_6 Methyltransferase domain - - - 0.00000001074 66.0
HKD1_k127_7235380_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 270.0
HKD1_k127_7235380_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000664 236.0
HKD1_k127_7235380_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000002195 221.0
HKD1_k127_7235380_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000001873 108.0
HKD1_k127_7235380_4 PFAM Mo-dependent nitrogenase - - - 0.0000466 52.0
HKD1_k127_7245977_0 E1-E2 ATPase K01531 - 3.6.3.2 1.055e-271 863.0
HKD1_k127_7245977_1 Penicillin amidase K01434 - 3.5.1.11 1.498e-221 713.0
HKD1_k127_7245977_2 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 404.0
HKD1_k127_7245977_3 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 332.0
HKD1_k127_7245977_4 molybdopterin K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 329.0
HKD1_k127_7245977_5 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HKD1_k127_7245977_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
HKD1_k127_7245977_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000009112 136.0
HKD1_k127_7245977_8 Peptidase family M23 K21472 - - 0.00000000000000000000001133 117.0
HKD1_k127_7245977_9 PFAM conserved - - - 0.0000003536 60.0
HKD1_k127_7251570_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 518.0
HKD1_k127_7251570_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 374.0
HKD1_k127_7251570_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000001741 221.0
HKD1_k127_7251570_5 Belongs to the UPF0235 family K09131 - - 0.0000000000000000004368 90.0
HKD1_k127_7251570_7 Diguanylate cyclase, GGDEF domain - - - 0.000000000009961 78.0
HKD1_k127_7251570_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.00000000002429 72.0
HKD1_k127_7260781_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 575.0
HKD1_k127_7260781_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000002984 203.0
HKD1_k127_7260781_2 - - - - 0.000000000000000000000000000000000000000000000000216 181.0
HKD1_k127_7260781_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000003022 174.0
HKD1_k127_7260781_4 Sporulation related domain - - - 0.00000000000000000000000000000000000001004 167.0
HKD1_k127_7260781_5 Membrane K08988 - - 0.00000000000000000000000003177 123.0
HKD1_k127_7260781_7 acid phosphatase activity - - - 0.000000006618 68.0
HKD1_k127_7263138_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 536.0
HKD1_k127_7263138_1 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 380.0
HKD1_k127_7263138_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 368.0
HKD1_k127_7263138_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 368.0
HKD1_k127_7263138_4 Phenazine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 322.0
HKD1_k127_7263138_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
HKD1_k127_7263138_6 Diguanylate cyclase K13069 - 2.7.7.65 0.0006155 53.0
HKD1_k127_728886_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 368.0
HKD1_k127_7297868_0 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 465.0
HKD1_k127_7297868_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 329.0
HKD1_k127_7297868_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
HKD1_k127_7297868_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000001039 157.0
HKD1_k127_731270_0 dehydrogenase e1 component K00164 - 1.2.4.2 2.156e-280 883.0
HKD1_k127_7313942_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008677 253.0
HKD1_k127_7313942_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000002557 177.0
HKD1_k127_7313942_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000002954 119.0
HKD1_k127_7313942_4 cellulose binding - - - 0.00000001427 66.0
HKD1_k127_7314928_0 AMP-binding enzyme K01897 - 6.2.1.3 5.047e-225 712.0
HKD1_k127_7314928_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 538.0
HKD1_k127_7314928_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000001321 105.0
HKD1_k127_7314928_4 Copper amine oxidase N-terminal domain - - - 0.000000000000000001112 99.0
HKD1_k127_7314928_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000006154 58.0
HKD1_k127_731604_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.398e-211 662.0
HKD1_k127_731604_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000007075 156.0
HKD1_k127_731604_2 KR domain - - - 0.000000000000000000000000000000000000188 147.0
HKD1_k127_731604_3 SMART Integrin alpha beta-propellor repeat protein - - - 0.0005125 48.0
HKD1_k127_7317550_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.894e-221 700.0
HKD1_k127_7317550_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 394.0
HKD1_k127_7317550_2 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007874 255.0
HKD1_k127_7317550_3 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004853 227.0
HKD1_k127_7317550_4 - - - - 0.00000000000000000000000000000000002115 154.0
HKD1_k127_7317550_5 cellulose binding - - - 0.000000000000000000000000000004547 137.0
HKD1_k127_7317550_6 NUDIX domain K12152 - - 0.00000000000000000000001143 105.0
HKD1_k127_7317550_7 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000004107 113.0
HKD1_k127_7317550_8 ECF sigma factor K03088 - - 0.0000000000000000001704 95.0
HKD1_k127_7317550_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000001653 99.0
HKD1_k127_7337510_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000005583 224.0
HKD1_k127_7337510_1 - - - - 0.0000000000000000000000000007993 130.0
HKD1_k127_7337510_2 - - - - 0.00002755 55.0
HKD1_k127_733827_0 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 584.0
HKD1_k127_733827_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 443.0
HKD1_k127_733827_2 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 336.0
HKD1_k127_733827_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 310.0
HKD1_k127_733827_5 acyl-CoA dehydrogenase K00257 - - 0.000000000000000000000000000000000000000007811 160.0
HKD1_k127_733827_6 Family membership - - - 0.00000000000000000000000000000001693 146.0
HKD1_k127_733827_7 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000001381 96.0
HKD1_k127_733827_8 serine threonine protein kinase - - - 0.0000000000000000106 98.0
HKD1_k127_733827_9 Galactose oxidase, central domain - - - 0.000004578 60.0
HKD1_k127_73433_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 357.0
HKD1_k127_73433_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
HKD1_k127_73433_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000005867 229.0
HKD1_k127_73433_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000524 212.0
HKD1_k127_73433_6 - - - - 0.000000000000000000000000001222 120.0
HKD1_k127_73433_7 Arrestin domain containing 1 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006858,GO:0008104,GO:0008150,GO:0008152,GO:0008593,GO:0009056,GO:0009057,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0015031,GO:0015833,GO:0016020,GO:0016567,GO:0019538,GO:0019899,GO:0019941,GO:0023051,GO:0023057,GO:0030163,GO:0030674,GO:0031410,GO:0031625,GO:0031982,GO:0032446,GO:0033036,GO:0036211,GO:0042802,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043412,GO:0043632,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0045746,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051603,GO:0060090,GO:0065007,GO:0070647,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097708,GO:0140112,GO:1901564,GO:1901565,GO:1901575,GO:1903561,GO:1990756,GO:1990763 - 0.0000906 55.0
HKD1_k127_7354791_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 381.0
HKD1_k127_7354791_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000005797 214.0
HKD1_k127_7354791_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000105 160.0
HKD1_k127_7354791_3 PEGA domain - - - 0.0000000000001386 78.0
HKD1_k127_7354791_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000003719 61.0
HKD1_k127_7365912_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 601.0
HKD1_k127_7365912_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 451.0
HKD1_k127_7365912_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000218 137.0
HKD1_k127_7365912_11 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000007059 103.0
HKD1_k127_7365912_12 - - - - 0.0000000000000000002659 97.0
HKD1_k127_7365912_13 PilZ domain - - - 0.00000000004611 67.0
HKD1_k127_7365912_14 Bacterial regulatory proteins, tetR family - - - 0.00000000132 66.0
HKD1_k127_7365912_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 317.0
HKD1_k127_7365912_3 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 284.0
HKD1_k127_7365912_4 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002102 293.0
HKD1_k127_7365912_5 COGs COG2343 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000005519 220.0
HKD1_k127_7365912_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000009449 168.0
HKD1_k127_739261_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1156.0
HKD1_k127_739261_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.406e-260 826.0
HKD1_k127_739261_2 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 449.0
HKD1_k127_739261_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006267 282.0
HKD1_k127_739261_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000004632 193.0
HKD1_k127_740950_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001791 275.0
HKD1_k127_740950_1 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000002503 222.0
HKD1_k127_740950_2 Methyltransferase domain - - - 0.0000000000000000000000000000000008257 149.0
HKD1_k127_740950_3 - - - - 0.0000000000000000000000000006908 130.0
HKD1_k127_740950_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000001105 126.0
HKD1_k127_740950_5 PFAM methyltransferase - - - 0.000000000003219 79.0
HKD1_k127_740950_7 - - - - 0.000000008908 68.0
HKD1_k127_740950_8 Bacterial membrane protein, YfhO - - - 0.000004986 60.0
HKD1_k127_740950_9 - - - - 0.00002134 54.0
HKD1_k127_745215_0 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 539.0
HKD1_k127_745215_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000228 225.0
HKD1_k127_745215_2 - - - - 0.0000005779 57.0
HKD1_k127_7456857_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006533 293.0
HKD1_k127_7456857_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000008178 226.0
HKD1_k127_7456857_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000001072 209.0
HKD1_k127_7456857_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000004622 126.0
HKD1_k127_7456857_4 Sel1-like repeats. K07126 - - 0.00000000000000000000008696 109.0
HKD1_k127_7456857_5 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.0000000000000001474 84.0
HKD1_k127_7456857_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000171 71.0
HKD1_k127_7458688_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.379e-272 872.0
HKD1_k127_7458688_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 383.0
HKD1_k127_7458688_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 304.0
HKD1_k127_7458688_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000149 140.0
HKD1_k127_7458688_4 Tetratricopeptide repeat - - - 0.0004779 51.0
HKD1_k127_746411_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 473.0
HKD1_k127_746411_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008362 259.0
HKD1_k127_746411_2 Domain of unknown function (DUF4281) - - - 0.0000000000000000000000000000000000000004241 154.0
HKD1_k127_746411_3 - - - - 0.00000000000000000000000001671 119.0
HKD1_k127_7473826_0 Glycogen debranching enzyme - - - 0.0 1399.0
HKD1_k127_7473826_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 619.0
HKD1_k127_7473826_2 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001679 283.0
HKD1_k127_7473826_3 - - - - 0.0000000000000000000000000000000000000000000000000000005769 201.0
HKD1_k127_7473826_5 Alpha amylase, catalytic domain - - - 0.0000000000000000000000009219 120.0
HKD1_k127_7473826_6 Belongs to the ompA family K03640 - - 0.00000000000000000000149 109.0
HKD1_k127_7475821_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000002127 97.0
HKD1_k127_7475821_1 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000000008267 75.0
HKD1_k127_7490676_1 belongs to the thioredoxin family K03671,K05838,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 281.0
HKD1_k127_7490676_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HKD1_k127_7490676_3 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000235 188.0
HKD1_k127_7497623_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.747e-240 749.0
HKD1_k127_7497623_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
HKD1_k127_7510770_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000408 202.0
HKD1_k127_7510770_2 Transcription factor zinc-finger - - - 0.0002477 48.0
HKD1_k127_7536414_0 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
HKD1_k127_7536414_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
HKD1_k127_7536414_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000001676 198.0
HKD1_k127_7536414_6 MFS/sugar transport protein - - - 0.0003507 45.0
HKD1_k127_7552552_1 S-layer homology domain - - - 0.000000000000000001965 99.0
HKD1_k127_7552552_2 thiolester hydrolase activity - - - 0.00000002034 68.0
HKD1_k127_7552552_3 amine dehydrogenase activity - - - 0.0002541 53.0
HKD1_k127_7560153_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 377.0
HKD1_k127_7560153_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000002884 225.0
HKD1_k127_7560153_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000001416 139.0
HKD1_k127_7560153_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000005866 54.0
HKD1_k127_7560153_4 regulation of response to stimulus K19613 - - 0.0005175 51.0
HKD1_k127_7561253_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 8.79e-213 679.0
HKD1_k127_7561253_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.491e-198 629.0
HKD1_k127_7561253_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HKD1_k127_7562834_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 415.0
HKD1_k127_7562834_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
HKD1_k127_7562834_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 348.0
HKD1_k127_759302_0 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HKD1_k127_759302_1 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 420.0
HKD1_k127_759302_2 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009855 373.0
HKD1_k127_760564_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 261.0
HKD1_k127_760564_1 Phosphate acyltransferases - - - 0.000000000000000000000000006219 122.0
HKD1_k127_760564_2 Major Facilitator Superfamily K03301 - - 0.000000000003869 80.0
HKD1_k127_760564_3 Universal stress protein - - - 0.0000000001368 67.0
HKD1_k127_7610257_0 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 534.0
HKD1_k127_7610257_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000002053 207.0
HKD1_k127_7610257_2 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.0000000000000002 88.0
HKD1_k127_7610257_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000004801 90.0
HKD1_k127_7610257_4 Peptidoglycan-binding domain 1 protein - - - 0.000000005134 69.0
HKD1_k127_7610257_5 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00005607 55.0
HKD1_k127_7624319_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 425.0
HKD1_k127_7624319_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003511 242.0
HKD1_k127_7624319_2 Protein of unknown function DUF47 K07220 - - 0.00000007511 62.0
HKD1_k127_764113_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 393.0
HKD1_k127_764113_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 350.0
HKD1_k127_764113_10 Belongs to the BolA IbaG family - - - 0.00000000000000000000000004342 115.0
HKD1_k127_764113_11 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000001784 115.0
HKD1_k127_764113_12 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000009278 120.0
HKD1_k127_764113_13 amine dehydrogenase activity - - - 0.0000000000000000003452 102.0
HKD1_k127_764113_14 Thioredoxin-like - - - 0.000000000000000148 83.0
HKD1_k127_764113_15 - - - - 0.0000000000001724 81.0
HKD1_k127_764113_16 Sel1-like repeats. K07126 - - 0.00000006802 61.0
HKD1_k127_764113_17 - - - - 0.000002044 59.0
HKD1_k127_764113_18 negative regulation of translational initiation - - - 0.000005398 56.0
HKD1_k127_764113_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.000009139 55.0
HKD1_k127_764113_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 344.0
HKD1_k127_764113_20 - - - - 0.00001816 55.0
HKD1_k127_764113_21 - - - - 0.00009998 48.0
HKD1_k127_764113_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001737 276.0
HKD1_k127_764113_4 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002649 248.0
HKD1_k127_764113_5 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000002181 205.0
HKD1_k127_764113_6 chlorophyll binding K16191,K20276 - - 0.000000000000000000000000000000000000000000000000002268 195.0
HKD1_k127_764113_7 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000009225 183.0
HKD1_k127_764113_8 ABC transporter - - - 0.000000000000000000000000000000001201 146.0
HKD1_k127_764113_9 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K00836,K06137 - 1.3.3.11,2.6.1.76 0.000000000000000000000000000004757 139.0
HKD1_k127_765367_0 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 627.0
HKD1_k127_765367_1 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 311.0
HKD1_k127_765367_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
HKD1_k127_765367_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000009319 177.0
HKD1_k127_7656400_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 471.0
HKD1_k127_7656400_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 393.0
HKD1_k127_7656400_2 Redoxin K03564 - 1.11.1.15 0.000000000000000005701 84.0
HKD1_k127_7666542_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 416.0
HKD1_k127_7666542_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009794 248.0
HKD1_k127_7666542_2 - - - - 0.00000000000000000000000000000000000000000000000000004366 206.0
HKD1_k127_7666542_3 Domain of unknown function (DUF4870) K09940 - - 0.00006424 50.0
HKD1_k127_7666542_4 chitin binding - - - 0.0004779 51.0
HKD1_k127_7666542_5 MotA/TolQ/ExbB proton channel family - - - 0.0005617 48.0
HKD1_k127_7667535_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 335.0
HKD1_k127_7667535_2 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000001657 204.0
HKD1_k127_7667535_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000003533 150.0
HKD1_k127_7667535_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000004138 55.0
HKD1_k127_7671178_0 deoxyhypusine monooxygenase activity - - - 6.413e-246 786.0
HKD1_k127_7671178_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 349.0
HKD1_k127_7671178_2 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009207 266.0
HKD1_k127_7671178_3 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000001243 244.0
HKD1_k127_7671178_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
HKD1_k127_7671178_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000001118 171.0
HKD1_k127_7671178_6 iron-sulfur cluster assembly K07126,K13819 - - 0.00000000000007826 74.0
HKD1_k127_7671178_7 lipolytic protein G-D-S-L family - - - 0.0002402 53.0
HKD1_k127_7687354_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 307.0
HKD1_k127_7687354_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000001174 217.0
HKD1_k127_7687354_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000003406 212.0
HKD1_k127_7687354_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000245 168.0
HKD1_k127_7687354_4 - - - - 0.00000000000000000000000000001367 123.0
HKD1_k127_7687354_5 - - - - 0.0000000000000000000000026 113.0
HKD1_k127_7692275_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 293.0
HKD1_k127_7692275_2 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000006413 158.0
HKD1_k127_7692275_4 - - - - 0.0000000000007688 79.0
HKD1_k127_7709015_0 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 460.0
HKD1_k127_7709015_1 Zinc finger, swim domain protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000003885 117.0
HKD1_k127_7709015_2 - - - - 0.0000000000000008049 83.0
HKD1_k127_7712521_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 377.0
HKD1_k127_7712521_1 Gaf domain - - - 0.00000000000000000000000000000002086 140.0
HKD1_k127_7714246_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1045.0
HKD1_k127_7714246_1 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 409.0
HKD1_k127_7714246_10 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340 - 1.6.5.3 0.0000000000000000002343 100.0
HKD1_k127_7714246_11 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000003175 94.0
HKD1_k127_7714246_12 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.0000000000000000006214 101.0
HKD1_k127_7714246_13 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000181 82.0
HKD1_k127_7714246_2 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
HKD1_k127_7714246_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 354.0
HKD1_k127_7714246_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 337.0
HKD1_k127_7714246_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 291.0
HKD1_k127_7714246_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000189 192.0
HKD1_k127_7714246_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002904 160.0
HKD1_k127_7714246_8 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000001037 147.0
HKD1_k127_7714246_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000001523 104.0
HKD1_k127_7717223_0 ABC transporter K06147,K18889 - - 2.22e-217 689.0
HKD1_k127_7717223_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 403.0
HKD1_k127_7717223_2 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002681 256.0
HKD1_k127_7717223_5 - - - - 0.0006044 48.0
HKD1_k127_7722914_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 353.0
HKD1_k127_7722914_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002485 282.0
HKD1_k127_7722914_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000004053 122.0
HKD1_k127_7728736_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 346.0
HKD1_k127_7728736_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004549 263.0
HKD1_k127_7728736_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000001513 216.0
HKD1_k127_7730327_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
HKD1_k127_7730327_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000275 181.0
HKD1_k127_7730327_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000001253 131.0
HKD1_k127_7730327_3 protein kinase activity - - - 0.00000000000000000000000000000128 132.0
HKD1_k127_7730327_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000236 119.0
HKD1_k127_7730674_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 363.0
HKD1_k127_7730674_1 cellulose binding - - - 0.0000000000000000006857 101.0
HKD1_k127_7742669_0 Penicillin amidase K01434 - 3.5.1.11 1.032e-249 802.0
HKD1_k127_7742669_1 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000001931 168.0
HKD1_k127_7745280_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007264 261.0
HKD1_k127_7745280_1 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000002083 62.0
HKD1_k127_7756807_1 Myo-inositol-1-phosphate synthase GAPDH domain protein K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 391.0
HKD1_k127_7756807_2 GH3 auxin-responsive promoter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001509 259.0
HKD1_k127_7756807_3 Belongs to the ompA family K03286 - - 0.0000000000000001348 86.0
HKD1_k127_7756807_4 YCII-related domain - - - 0.00006142 47.0
HKD1_k127_7764974_0 nUDIX hydrolase - - - 0.0000000000000000000000000000007818 138.0
HKD1_k127_7764974_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000002874 128.0
HKD1_k127_7764974_4 - - - - 0.0005593 49.0
HKD1_k127_7768495_0 Acid phosphatase homologues - - - 0.000000000000000000000000000000004193 141.0
HKD1_k127_7768495_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000003385 108.0
HKD1_k127_7768495_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000001098 87.0
HKD1_k127_7768495_3 - - - - 0.000000002488 69.0
HKD1_k127_7776836_0 PFAM SpoVR family protein K06415 - - 4.837e-235 749.0
HKD1_k127_7776836_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 553.0
HKD1_k127_7776836_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
HKD1_k127_7776836_3 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000005305 184.0
HKD1_k127_7776836_4 Cold shock protein K03704 - - 0.0000000000000000000000000000000002291 133.0
HKD1_k127_7776836_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000008535 97.0
HKD1_k127_7776836_7 integral membrane protein - - - 0.00004237 56.0
HKD1_k127_7780254_0 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 481.0
HKD1_k127_7780254_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 431.0
HKD1_k127_7780254_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 387.0
HKD1_k127_7780254_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 376.0
HKD1_k127_7780254_4 TIGRFAM sulfate ABC transporter, inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 323.0
HKD1_k127_7780254_5 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
HKD1_k127_7780254_6 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000001004 196.0
HKD1_k127_7780254_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000009075 168.0
HKD1_k127_7780254_8 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.000000000000000000000000000000659 125.0
HKD1_k127_7793733_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 591.0
HKD1_k127_7793733_1 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 527.0
HKD1_k127_7793733_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000001236 169.0
HKD1_k127_7793871_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 490.0
HKD1_k127_7793871_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 402.0
HKD1_k127_7793871_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
HKD1_k127_7793871_3 PA14 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
HKD1_k127_7793871_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003794 214.0
HKD1_k127_7793871_5 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000001344 215.0
HKD1_k127_7793871_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000005005 190.0
HKD1_k127_7793871_7 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000002192 170.0
HKD1_k127_7806116_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 348.0
HKD1_k127_7806116_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005841 290.0
HKD1_k127_7806116_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002153 220.0
HKD1_k127_7806116_3 Bacterial PH domain K08981 - - 0.000000000000000000000000000000000000000000003446 171.0
HKD1_k127_7806116_4 Bacterial PH domain - - - 0.000000000000000000000000000001563 134.0
HKD1_k127_7806116_5 - - - - 0.000004012 53.0
HKD1_k127_7807000_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 473.0
HKD1_k127_7807000_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000005292 234.0
HKD1_k127_7807000_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000006258 146.0
HKD1_k127_7808607_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 609.0
HKD1_k127_7808607_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 447.0
HKD1_k127_7808607_2 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 384.0
HKD1_k127_7808607_3 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 379.0
HKD1_k127_7808607_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 254.0
HKD1_k127_7808607_5 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000436 93.0
HKD1_k127_7808607_6 SMART serine threonine protein kinase - - - 0.0000000000004358 72.0
HKD1_k127_7820504_0 Flagellar Motor Protein K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 507.0
HKD1_k127_7820504_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 300.0
HKD1_k127_7820504_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000002004 195.0
HKD1_k127_7820504_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000002525 169.0
HKD1_k127_7820504_4 Stigma-specific protein, Stig1 - - - 0.00000000000000001544 96.0
HKD1_k127_7833035_0 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
HKD1_k127_7833035_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 376.0
HKD1_k127_7833035_2 DoxX-like family - - - 0.000000000000000000000000000000000000000000883 160.0
HKD1_k127_7833035_3 Serine aminopeptidase, S33 - - - 0.000000007252 65.0
HKD1_k127_7847683_0 Belongs to the peptidase S8 family - - - 6.138e-209 676.0
HKD1_k127_7847683_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 487.0
HKD1_k127_7847683_10 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000000000001019 130.0
HKD1_k127_7847683_11 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000007825 106.0
HKD1_k127_7847683_12 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000002754 104.0
HKD1_k127_7847683_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001068 83.0
HKD1_k127_7847683_15 Cupredoxin-like domain - - - 0.00000000000004383 79.0
HKD1_k127_7847683_16 domain protein K13730 - - 0.000000000002501 80.0
HKD1_k127_7847683_17 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000001324 58.0
HKD1_k127_7847683_18 - - - - 0.0000639 48.0
HKD1_k127_7847683_2 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 340.0
HKD1_k127_7847683_3 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 298.0
HKD1_k127_7847683_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000961 280.0
HKD1_k127_7847683_5 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000493 287.0
HKD1_k127_7847683_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000005635 255.0
HKD1_k127_7847683_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000004557 215.0
HKD1_k127_7847683_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000004194 162.0
HKD1_k127_7847683_9 Phosphoesterase family - - - 0.000000000000000000000000000000008701 144.0
HKD1_k127_7847732_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 428.0
HKD1_k127_7847732_1 phosphate ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000461 272.0
HKD1_k127_7847732_2 - - - - 0.000007896 51.0
HKD1_k127_7847898_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 373.0
HKD1_k127_7847898_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000006862 231.0
HKD1_k127_7847898_2 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.000000000000000000000000004772 120.0
HKD1_k127_7854881_0 Belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 510.0
HKD1_k127_7854881_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 301.0
HKD1_k127_7854881_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 300.0
HKD1_k127_7854881_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 296.0
HKD1_k127_7854881_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000004338 192.0
HKD1_k127_7864227_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 4.742e-250 784.0
HKD1_k127_7864227_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 456.0
HKD1_k127_7864227_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001121 237.0
HKD1_k127_7864227_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 237.0
HKD1_k127_7864227_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000005454 171.0
HKD1_k127_7867250_0 Methionine synthase K00548 - 2.1.1.13 0.0 1139.0
HKD1_k127_7867250_1 Calcineurin-like phosphoesterase superfamily domain K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 365.0
HKD1_k127_7867250_10 Transcriptional regulator - - - 0.000000000007887 73.0
HKD1_k127_7867250_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 355.0
HKD1_k127_7867250_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K17681 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 336.0
HKD1_k127_7867250_4 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000003941 209.0
HKD1_k127_7867250_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000001898 190.0
HKD1_k127_7867250_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000003199 196.0
HKD1_k127_7867250_7 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000479 179.0
HKD1_k127_7867250_8 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000000000000000000008827 169.0
HKD1_k127_7867250_9 Transcriptional regulator - - - 0.000000000000001506 81.0
HKD1_k127_7867854_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 281.0
HKD1_k127_7867854_1 zinc ion binding - - - 0.000000000000007842 89.0
HKD1_k127_7875874_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 430.0
HKD1_k127_7875874_1 transmembrane transport K03442,K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 390.0
HKD1_k127_7875874_2 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 287.0
HKD1_k127_7875874_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000002592 146.0
HKD1_k127_7875874_4 Sodium hydrogen exchanger - - - 0.00000000000000002059 84.0
HKD1_k127_7882988_0 CoA-substrate-specific enzyme activase - - - 0.0 1866.0
HKD1_k127_7882988_1 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 524.0
HKD1_k127_7882988_12 lipoprotein receptor K12473,K20053 GO:0000323,GO:0001101,GO:0001540,GO:0001666,GO:0002020,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003008,GO:0003674,GO:0005041,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005769,GO:0005770,GO:0005771,GO:0005773,GO:0005774,GO:0005794,GO:0005886,GO:0005887,GO:0005901,GO:0005905,GO:0006066,GO:0006629,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006897,GO:0006898,GO:0006950,GO:0007275,GO:0007399,GO:0007568,GO:0007586,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009056,GO:0009057,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009897,GO:0009986,GO:0009987,GO:0009991,GO:0010008,GO:0010033,GO:0010243,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010721,GO:0010866,GO:0010867,GO:0010876,GO:0010896,GO:0010898,GO:0010899,GO:0010984,GO:0010986,GO:0012505,GO:0012506,GO:0014013,GO:0014014,GO:0014070,GO:0015711,GO:0015748,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016021,GO:0016043,GO:0016125,GO:0016192,GO:0016323,GO:0019216,GO:0019218,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0022008,GO:0022600,GO:0030100,GO:0030135,GO:0030136,GO:0030139,GO:0030154,GO:0030163,GO:0030169,GO:0030228,GO:0030229,GO:0030276,GO:0030299,GO:0030301,GO:0030659,GO:0030662,GO:0030665,GO:0030666,GO:0030669,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031347,GO:0031349,GO:0031410,GO:0031667,GO:0031982,GO:0032050,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032355,GO:0032365,GO:0032366,GO:0032367,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0033036,GO:0033218,GO:0033762,GO:0033993,GO:0034381,GO:0034382,GO:0034383,GO:0035376,GO:0036019,GO:0036020,GO:0036293,GO:0036477,GO:0038024,GO:0042157,GO:0042159,GO:0042176,GO:0042221,GO:0042277,GO:0042592,GO:0042632,GO:0042802,GO:0043030,GO:0043031,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043434,GO:0043627,GO:0044238,GO:0044241,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0044877,GO:0045056,GO:0045121,GO:0045177,GO:0045334,GO:0045595,GO:0045596,GO:0045685,GO:0045686,GO:0045732,GO:0045807,GO:0045834,GO:0046889,GO:0046890,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048699,GO:0048710,GO:0048712,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050727,GO:0050729,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050865,GO:0050866,GO:0050877,GO:0050890,GO:0050892,GO:0050896,GO:0050994,GO:0050996,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051641,GO:0051649,GO:0051716,GO:0051960,GO:0051961,GO:0055037,GO:0055038,GO:0055088,GO:0055092,GO:0055094,GO:0060255,GO:0060284,GO:0060627,GO:0060696,GO:0061024,GO:0061771,GO:0061888,GO:0061889,GO:0062012,GO:0065007,GO:0065008,GO:0070482,GO:0070508,GO:0070542,GO:0070887,GO:0071229,GO:0071310,GO:0071396,GO:0071398,GO:0071402,GO:0071404,GO:0071702,GO:0071704,GO:0071813,GO:0071814,GO:0071830,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0090118,GO:0090181,GO:0090207,GO:0090208,GO:0097006,GO:0097242,GO:0097443,GO:0097458,GO:0097708,GO:0098552,GO:0098588,GO:0098589,GO:0098590,GO:0098657,GO:0098805,GO:0098852,GO:0098856,GO:0098857,GO:1900221,GO:1900223,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901652,GO:1901698,GO:1901700,GO:1901701,GO:1902652,GO:1902903,GO:1902904,GO:1903362,GO:1903364,GO:1903725,GO:1903978,GO:1903979,GO:1904350,GO:1904352,GO:1905165,GO:1905167,GO:1905906,GO:1905907,GO:1990666,GO:2000026 - 0.0002695 52.0
HKD1_k127_7882988_2 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 475.0
HKD1_k127_7882988_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000002668 242.0
HKD1_k127_7882988_4 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000103 201.0
HKD1_k127_7882988_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
HKD1_k127_7882988_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000004518 184.0
HKD1_k127_7882988_7 Acetyl-coenzyme A transporter 1 - - - 0.000000000000000000000000000000000000000000000453 181.0
HKD1_k127_7882988_8 Peptidase C26 K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000004547 183.0
HKD1_k127_7882988_9 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000001042 118.0
HKD1_k127_7883081_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 387.0
HKD1_k127_7883081_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000005227 197.0
HKD1_k127_7886214_0 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 333.0
HKD1_k127_7886214_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 308.0
HKD1_k127_7886214_2 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 301.0
HKD1_k127_7886214_3 rRNA methyltransferase activity K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000001735 176.0
HKD1_k127_7886214_4 Flagellar basal body rod K02396 - - 0.00000000000000000000000000000005779 140.0
HKD1_k127_7886214_5 Protein kinase domain - - - 0.0000000000000005346 81.0
HKD1_k127_7886214_6 - - - - 0.00000000008328 74.0
HKD1_k127_7886214_7 MORN repeat variant - - - 0.0000000004021 71.0
HKD1_k127_7886214_8 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 0.0000003962 61.0
HKD1_k127_7886214_9 Leucine Rich repeat K02909,K14319 - - 0.0001153 55.0
HKD1_k127_7892849_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1015.0
HKD1_k127_7892849_1 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000007533 138.0
HKD1_k127_7892849_2 - - - - 0.00000000000000000000000008972 119.0
HKD1_k127_7904629_0 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 6.662e-201 648.0
HKD1_k127_7904629_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000006693 184.0
HKD1_k127_7904629_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000008258 98.0
HKD1_k127_7904629_3 helix_turn_helix, Lux Regulon - - - 0.00008203 51.0
HKD1_k127_7921239_0 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 533.0
HKD1_k127_7921239_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 433.0
HKD1_k127_7921239_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000001606 214.0
HKD1_k127_7921239_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000238 183.0
HKD1_k127_7921239_4 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000003218 192.0
HKD1_k127_7921239_8 - - - - 0.0000000001582 73.0
HKD1_k127_7921239_9 - - - - 0.000004013 60.0
HKD1_k127_7921454_0 Aldo Keto reductase K01939,K03273,K05275 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 1.1.1.65,3.1.3.82,3.1.3.83,6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000002525 243.0
HKD1_k127_7921454_1 Protein conserved in bacteria K09983 - - 0.000000000000000000000000000000000000000000000007002 183.0
HKD1_k127_7921454_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000009537 177.0
HKD1_k127_7921454_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000002305 155.0
HKD1_k127_7921454_4 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000001511 125.0
HKD1_k127_7921454_5 Protein of unknown function (DUF3750) - - - 0.0000000000000000008343 94.0
HKD1_k127_7921454_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000005885 57.0
HKD1_k127_7925943_0 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
HKD1_k127_7925943_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
HKD1_k127_7925943_2 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
HKD1_k127_7925943_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001485 295.0
HKD1_k127_7928342_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 556.0
HKD1_k127_7928342_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 410.0
HKD1_k127_7928342_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 386.0
HKD1_k127_7928342_3 CAAX protease self-immunity K07052 - - 0.0007342 50.0
HKD1_k127_794865_0 Protein phosphatase 2A homologues, catalytic domain. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 565.0
HKD1_k127_794865_1 Pilus formation protein N terminal region K02280 - - 0.00000007535 64.0
HKD1_k127_7954346_0 deoxyhypusine monooxygenase activity K21010 - - 0.00000000000000000383 96.0
HKD1_k127_7954346_1 - - - - 0.0000000000001079 81.0
HKD1_k127_7954931_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 437.0
HKD1_k127_7954931_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 366.0
HKD1_k127_7954931_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000001471 108.0
HKD1_k127_7954931_4 PFAM FecR protein - - - 0.00008423 55.0
HKD1_k127_7956142_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.539e-258 810.0
HKD1_k127_7956142_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 326.0
HKD1_k127_7956142_2 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005268 248.0
HKD1_k127_7956142_3 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000171 244.0
HKD1_k127_7956142_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000003903 194.0
HKD1_k127_7956142_5 phosphatase activity K07025 - - 0.0000000000000000000000003072 115.0
HKD1_k127_7956142_6 acid phosphatase activity - - - 0.00000000000000001095 97.0
HKD1_k127_7956142_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000003951 59.0
HKD1_k127_7956142_9 SMI1 / KNR4 family - - - 0.000008225 57.0
HKD1_k127_7956299_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 561.0
HKD1_k127_7956299_1 Parallel beta-helix repeats - - - 0.00000000000585 79.0
HKD1_k127_7956299_2 Tetratricopeptide repeat - - - 0.000001836 59.0
HKD1_k127_7976672_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1080.0
HKD1_k127_7976672_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 400.0
HKD1_k127_7976672_10 Domain of unknown function (DUF4412) - - - 0.00000001771 64.0
HKD1_k127_7976672_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
HKD1_k127_7976672_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 329.0
HKD1_k127_7976672_4 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 317.0
HKD1_k127_7976672_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000001064 282.0
HKD1_k127_7976672_6 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000001468 225.0
HKD1_k127_7976672_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000002702 198.0
HKD1_k127_7976672_8 Transcriptional - - - 0.0000000000000000000000000000000000000000002892 165.0
HKD1_k127_7976672_9 Tetratricopeptide repeat - - - 0.0000000000000000356 95.0
HKD1_k127_7982077_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000006662 193.0
HKD1_k127_7982077_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000007004 124.0
HKD1_k127_7982077_2 PTS system, Lactose/Cellobiose specific IIB subunit K02774 - 2.7.1.200 0.0000000000000000000003351 112.0
HKD1_k127_7982077_3 - - - - 0.0000000866 62.0
HKD1_k127_7982077_4 Putative addiction module component - - - 0.0000004037 55.0
HKD1_k127_7982077_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000004263 55.0
HKD1_k127_7990736_0 Zn-dependent proteases and their inactivated homologs K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 597.0
HKD1_k127_7990736_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 419.0
HKD1_k127_7990736_2 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 372.0
HKD1_k127_7990736_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007706 260.0
HKD1_k127_7990736_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
HKD1_k127_7990736_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000575 134.0
HKD1_k127_7990736_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000911 141.0
HKD1_k127_7990736_8 sequence-specific DNA binding K07726 - - 0.0000000000000000000000000000006667 124.0
HKD1_k127_7993018_0 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 359.0
HKD1_k127_7993018_2 Phosphotransferase enzyme family - - - 0.00000000000000007727 90.0
HKD1_k127_7993018_3 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000297 85.0
HKD1_k127_8016075_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
HKD1_k127_8016075_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000007109 251.0
HKD1_k127_8016075_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.00000000000000000000000000000000000000000000000000000000006789 207.0
HKD1_k127_8016075_3 Methyltransferase domain K00588 - 2.1.1.104 0.000000000000000000000000000000000000002923 153.0
HKD1_k127_8036340_0 Alpha-amylase domain K01176 - 3.2.1.1 7.657e-211 679.0
HKD1_k127_8036340_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 411.0
HKD1_k127_8036340_2 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000000000000000000000000000000000000001834 222.0
HKD1_k127_814120_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1166.0
HKD1_k127_814120_1 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 1.181e-253 821.0
HKD1_k127_814120_10 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000003598 131.0
HKD1_k127_814120_11 NUDIX domain - - - 0.0000000000000000000000002001 119.0
HKD1_k127_814120_12 - - - - 0.000000000000000003832 90.0
HKD1_k127_814120_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000002885 79.0
HKD1_k127_814120_14 COG3411 Ferredoxin - - - 0.000000005044 61.0
HKD1_k127_814120_16 - - - - 0.0000003119 59.0
HKD1_k127_814120_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 462.0
HKD1_k127_814120_3 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 398.0
HKD1_k127_814120_4 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 358.0
HKD1_k127_814120_6 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
HKD1_k127_814120_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002226 269.0
HKD1_k127_814120_8 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002496 273.0
HKD1_k127_814120_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000854 153.0
HKD1_k127_815148_0 - - - - 0.0000000000000000000000000000000000001516 146.0
HKD1_k127_815148_1 PAS fold - - - 0.000000000000000000000000001335 124.0
HKD1_k127_815148_2 Transcription factor zinc-finger K09981 - - 0.000000005217 64.0
HKD1_k127_815148_3 protein kinase activity - - - 0.0002934 48.0
HKD1_k127_817658_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1077.0
HKD1_k127_817658_1 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 1.693e-247 772.0
HKD1_k127_817658_10 Armadillo/beta-catenin-like repeats - - - 0.00000000000000000000003364 117.0
HKD1_k127_817658_11 - - - - 0.00000000000000000001341 101.0
HKD1_k127_817658_13 Major Facilitator Superfamily - - - 0.000006289 58.0
HKD1_k127_817658_2 DNA-binding response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 625.0
HKD1_k127_817658_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 577.0
HKD1_k127_817658_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 387.0
HKD1_k127_817658_5 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 339.0
HKD1_k127_817658_7 protein trimerization - - - 0.000000000000000000000000000000000000000000003122 187.0
HKD1_k127_817658_8 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000017 144.0
HKD1_k127_817658_9 acetyltransferase - - - 0.0000000000000000000000000000003974 141.0
HKD1_k127_843823_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 391.0
HKD1_k127_843823_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000001492 218.0
HKD1_k127_843823_3 40-residue YVTN family beta-propeller repeat - - - 0.00005097 56.0
HKD1_k127_84653_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 394.0
HKD1_k127_84653_1 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000000000000000000000000000000000000000000000000000000002693 226.0
HKD1_k127_84653_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000768 236.0
HKD1_k127_84653_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000007059 187.0
HKD1_k127_849371_0 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
HKD1_k127_849371_1 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007411 271.0
HKD1_k127_849371_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002023 239.0
HKD1_k127_849371_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000001871 154.0
HKD1_k127_849371_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000001751 82.0
HKD1_k127_849371_5 SnoaL-like domain - - - 0.00000002063 64.0
HKD1_k127_849439_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 574.0
HKD1_k127_849439_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 479.0
HKD1_k127_849439_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 375.0
HKD1_k127_849439_3 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000005283 190.0
HKD1_k127_849439_4 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000002006 98.0
HKD1_k127_849439_5 - - - - 0.00058 51.0
HKD1_k127_869095_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 576.0
HKD1_k127_869095_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 341.0
HKD1_k127_869095_2 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000008083 112.0
HKD1_k127_869095_4 Carbohydrate family 9 binding domain-like - - - 0.000000000000003576 77.0
HKD1_k127_869095_5 Protein of unknown function (DUF2752) - - - 0.00000008862 59.0
HKD1_k127_877111_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 3.729e-316 992.0
HKD1_k127_877111_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000001002 188.0
HKD1_k127_877111_2 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000005824 179.0
HKD1_k127_877111_3 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000001617 164.0
HKD1_k127_884425_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
HKD1_k127_884425_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000001212 229.0
HKD1_k127_884425_2 - - - - 0.00000000000000000000000000000000000000000000000000000001753 206.0
HKD1_k127_884425_3 - K06940 - - 0.0000000000000000000000000001887 117.0
HKD1_k127_884425_4 PFAM PQQ enzyme repeat - - - 0.00000000000001906 85.0
HKD1_k127_896769_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 496.0
HKD1_k127_896769_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 301.0
HKD1_k127_896769_2 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001625 260.0
HKD1_k127_896769_3 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000003803 199.0
HKD1_k127_896769_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000004278 210.0
HKD1_k127_896769_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000007414 166.0
HKD1_k127_896769_6 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000000000000000000000000000000000104 147.0
HKD1_k127_896769_8 Belongs to the peptidase S1B family K01318 - 3.4.21.19 0.0000000000000000000006605 104.0
HKD1_k127_89844_0 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000007658 259.0
HKD1_k127_89844_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000001476 235.0
HKD1_k127_89844_2 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000002084 131.0
HKD1_k127_89844_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000003866 83.0
HKD1_k127_904311_0 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 333.0
HKD1_k127_904311_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 325.0
HKD1_k127_904311_2 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 308.0
HKD1_k127_904311_3 - - - - 0.0000000000000000000000000000000000579 137.0
HKD1_k127_905616_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 506.0
HKD1_k127_905616_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 481.0
HKD1_k127_905616_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 409.0
HKD1_k127_905616_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 287.0
HKD1_k127_905616_4 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000000000000000000000000000000000023 229.0
HKD1_k127_905616_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000001119 197.0
HKD1_k127_905616_6 Domain of unknown function (DUF4398) - - - 0.000000000000004679 83.0
HKD1_k127_906156_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 1.928e-250 797.0
HKD1_k127_906156_1 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
HKD1_k127_906156_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000001202 208.0
HKD1_k127_919349_0 PrkA serine protein kinase C-terminal domain - - - 6.869e-293 917.0
HKD1_k127_919349_1 TIGRFAM MATE efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 317.0
HKD1_k127_919349_2 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002948 287.0
HKD1_k127_919349_3 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000002241 141.0
HKD1_k127_919349_5 - - - - 0.0000000000000002919 84.0
HKD1_k127_919349_6 beta-galactosidase activity - - - 0.0000000000003399 82.0
HKD1_k127_919349_7 - - - - 0.00001934 53.0
HKD1_k127_919349_8 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00003149 46.0
HKD1_k127_919349_9 - - - - 0.0002068 53.0
HKD1_k127_934427_0 ABC transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 550.0
HKD1_k127_934427_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 477.0
HKD1_k127_934427_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000003304 200.0
HKD1_k127_934427_3 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000001382 185.0
HKD1_k127_934427_4 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000004699 184.0
HKD1_k127_937540_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 432.0
HKD1_k127_937540_1 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 419.0
HKD1_k127_937540_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 310.0
HKD1_k127_937540_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001812 262.0
HKD1_k127_937540_4 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000716 183.0
HKD1_k127_937540_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000002348 170.0
HKD1_k127_937540_6 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000001188 136.0
HKD1_k127_937540_9 Domain of unknown function (DUF4266) - - - 0.00000004114 58.0
HKD1_k127_938001_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 6.012e-264 852.0
HKD1_k127_938001_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000002088 239.0
HKD1_k127_938001_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000008161 168.0
HKD1_k127_951316_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 8.137e-207 654.0
HKD1_k127_951316_1 FimV N-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002614 276.0
HKD1_k127_951316_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000234 130.0
HKD1_k127_951459_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
HKD1_k127_951459_1 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
HKD1_k127_95860_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.112e-268 845.0
HKD1_k127_95860_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 582.0
HKD1_k127_95860_10 Belongs to the sterol desaturase family K10223 GO:0001567,GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0006066,GO:0006082,GO:0006629,GO:0006694,GO:0006699,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008206,GO:0008395,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0012505,GO:0016020,GO:0016053,GO:0016125,GO:0016477,GO:0016491,GO:0016705,GO:0019752,GO:0030595,GO:0031984,GO:0032787,GO:0035754,GO:0040011,GO:0042175,GO:0042221,GO:0042330,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048247,GO:0048870,GO:0050896,GO:0050900,GO:0051179,GO:0051607,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0055114,GO:0060326,GO:0070887,GO:0071704,GO:0072330,GO:0072676,GO:0098542,GO:0098827,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1902652 1.14.99.38 0.0000007077 60.0
HKD1_k127_95860_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0006584 46.0
HKD1_k127_95860_2 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 552.0
HKD1_k127_95860_3 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 272.0
HKD1_k127_95860_4 twitching motility protein PilT K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002164 262.0
HKD1_k127_95860_5 - - - - 0.000000000000000000000000000000000000000000001037 185.0
HKD1_k127_95860_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000245 186.0
HKD1_k127_95860_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000003359 149.0
HKD1_k127_95860_8 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000003757 121.0
HKD1_k127_95860_9 - - - - 0.0000000000000000000000000004673 129.0
HKD1_k127_963378_0 von Willebrand factor type A domain - - - 0.0 1072.0
HKD1_k127_963378_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000044 194.0
HKD1_k127_963896_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 349.0
HKD1_k127_963896_1 - - - - 0.000000000000000000000000000000000375 136.0
HKD1_k127_963896_2 cytochrome P450 - - - 0.000000000000005486 76.0
HKD1_k127_969270_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 425.0
HKD1_k127_969270_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 398.0
HKD1_k127_969270_2 Rieske (2fe-2S) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000001716 192.0
HKD1_k127_969270_3 - - - - 0.000000000000000000000000000000000000000000004063 183.0
HKD1_k127_984145_0 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 599.0
HKD1_k127_984145_1 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 259.0
HKD1_k127_984145_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000006418 195.0
HKD1_k127_984145_3 - - - - 0.00000000000000000000000000000000000000386 153.0
HKD1_k127_984145_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000006496 96.0
HKD1_k127_999688_0 Protein of unknown function (DUF1588) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 536.0
HKD1_k127_999688_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 362.0
HKD1_k127_999688_11 - - - - 0.000000000000000000000000000009522 123.0
HKD1_k127_999688_12 cellulose binding - - - 0.0000000000006043 82.0
HKD1_k127_999688_13 COG3315 O-Methyltransferase involved in polyketide biosynthesis - - - 0.000000000001531 79.0
HKD1_k127_999688_14 PEGA domain - - - 0.000000000004053 68.0
HKD1_k127_999688_15 Transposase, Mutator family - - - 0.0000000002719 68.0
HKD1_k127_999688_16 cellulose binding K07279 - - 0.000007684 59.0
HKD1_k127_999688_17 Fatty acid desaturase K00508 - 1.14.19.3 0.00005044 55.0
HKD1_k127_999688_2 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 300.0
HKD1_k127_999688_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007714 281.0
HKD1_k127_999688_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000000000000000000000000003867 192.0
HKD1_k127_999688_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000008265 167.0
HKD1_k127_999688_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000002917 174.0
HKD1_k127_999688_7 protein trimerization - - - 0.0000000000000000000000000000000000000003932 171.0
HKD1_k127_999688_8 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000003912 162.0
HKD1_k127_999688_9 Putative transposase - - - 0.000000000000000000000000000000000000008812 154.0