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Overview

ID MAG01732
Name HKD1_bin.5
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Reyranellales
Family Reyranellaceae
Genus Reyranella
Species
Assembly information
Completeness (%) 93.46
Contamination (%) 1.88
GC content (%) 67.0
N50 (bp) 21,299
Genome size (bp) 5,462,726

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5189

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1018808_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1540.0
HKD1_k127_1018808_1 Poly(3-hydroxyalkanoate) synthetase - - - 0.0 1049.0
HKD1_k127_1018808_10 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 447.0
HKD1_k127_1018808_11 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 419.0
HKD1_k127_1018808_12 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
HKD1_k127_1018808_13 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 392.0
HKD1_k127_1018808_14 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HKD1_k127_1018808_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HKD1_k127_1018808_16 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 301.0
HKD1_k127_1018808_17 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004695 274.0
HKD1_k127_1018808_18 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000001668 209.0
HKD1_k127_1018808_2 Amidohydrolase family - - - 0.0 1023.0
HKD1_k127_1018808_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001405 174.0
HKD1_k127_1018808_21 Cytochrome c K17230 - - 0.00000000000000000000000000000000000000000000004088 177.0
HKD1_k127_1018808_22 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000004851 182.0
HKD1_k127_1018808_23 Cupin - - - 0.00000000000000000000000000001144 118.0
HKD1_k127_1018808_24 Pyrroloquinoline quinone biosynthesis protein D K06138 - - 0.000000000000000000000000009582 111.0
HKD1_k127_1018808_25 Peptidoglycan-binding domain 1 protein - - - 0.00000000001573 76.0
HKD1_k127_1018808_3 Sulfate permease family K03321 - - 2.88e-249 779.0
HKD1_k127_1018808_4 Pyridoxal-dependent decarboxylase conserved domain - - - 6.716e-195 618.0
HKD1_k127_1018808_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 604.0
HKD1_k127_1018808_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 575.0
HKD1_k127_1018808_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
HKD1_k127_1018808_8 peptidyl-tyrosine modification K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 489.0
HKD1_k127_1018808_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 453.0
HKD1_k127_1023952_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 7.922e-204 640.0
HKD1_k127_1023952_1 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000001005 162.0
HKD1_k127_1033913_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0 1083.0
HKD1_k127_1033913_1 Glycosyl hydrolases family 15 - - - 0.0 1054.0
HKD1_k127_1033913_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 3.643e-206 644.0
HKD1_k127_1033913_11 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 4.696e-196 613.0
HKD1_k127_1033913_12 Serine aminopeptidase, S33 - - - 9.881e-196 629.0
HKD1_k127_1033913_13 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 596.0
HKD1_k127_1033913_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 586.0
HKD1_k127_1033913_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 540.0
HKD1_k127_1033913_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 469.0
HKD1_k127_1033913_17 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 467.0
HKD1_k127_1033913_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00038 - 1.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 458.0
HKD1_k127_1033913_19 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 476.0
HKD1_k127_1033913_2 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 0.0 1019.0
HKD1_k127_1033913_20 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 480.0
HKD1_k127_1033913_21 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 440.0
HKD1_k127_1033913_22 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 452.0
HKD1_k127_1033913_23 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 419.0
HKD1_k127_1033913_24 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 408.0
HKD1_k127_1033913_25 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 396.0
HKD1_k127_1033913_26 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 364.0
HKD1_k127_1033913_27 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 357.0
HKD1_k127_1033913_28 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 344.0
HKD1_k127_1033913_29 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 317.0
HKD1_k127_1033913_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.2e-322 996.0
HKD1_k127_1033913_30 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
HKD1_k127_1033913_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001927 263.0
HKD1_k127_1033913_32 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000000000000004272 231.0
HKD1_k127_1033913_33 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000009394 200.0
HKD1_k127_1033913_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000002069 181.0
HKD1_k127_1033913_35 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000002691 150.0
HKD1_k127_1033913_36 PFAM Dimethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000001398 149.0
HKD1_k127_1033913_37 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000002466 137.0
HKD1_k127_1033913_38 - - - - 0.00000000000000000000000000000000002956 139.0
HKD1_k127_1033913_39 CHAP domain - - - 0.0000000000000000000000000000000001344 150.0
HKD1_k127_1033913_4 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 6.434e-314 967.0
HKD1_k127_1033913_40 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000006544 130.0
HKD1_k127_1033913_41 YHS domain protein - - - 0.00000000000000000000000000000009311 130.0
HKD1_k127_1033913_42 FeoA K04758 - - 0.00000000000000000000000000226 117.0
HKD1_k127_1033913_43 integral membrane protein - - - 0.000000000000000000000003687 109.0
HKD1_k127_1033913_44 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000005111 110.0
HKD1_k127_1033913_46 electron transfer activity K08738 - - 0.00000000000000000002548 106.0
HKD1_k127_1033913_48 EamA-like transporter family - - - 0.0000000000008207 80.0
HKD1_k127_1033913_49 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000006706 66.0
HKD1_k127_1033913_5 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 7.32e-296 917.0
HKD1_k127_1033913_51 receptor - - - 0.000000001235 61.0
HKD1_k127_1033913_52 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000435 64.0
HKD1_k127_1033913_53 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00004754 45.0
HKD1_k127_1033913_6 Amidase - - - 7.206e-267 826.0
HKD1_k127_1033913_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 2.001e-247 777.0
HKD1_k127_1033913_8 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 1.034e-238 739.0
HKD1_k127_1033913_9 Aminotransferase class-V - - - 9.574e-223 693.0
HKD1_k127_1037926_0 elongator protein 3 miab nifb - - - 2.953e-265 830.0
HKD1_k127_1037926_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 558.0
HKD1_k127_1037926_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 405.0
HKD1_k127_1037926_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 406.0
HKD1_k127_1037926_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 314.0
HKD1_k127_1037926_5 Binding-protein-dependent transport system inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 282.0
HKD1_k127_1037926_6 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001072 249.0
HKD1_k127_1037926_7 - - - - 0.000000000000000000003129 97.0
HKD1_k127_1037926_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000002711 79.0
HKD1_k127_1046632_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 559.0
HKD1_k127_1053770_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 1.436e-238 744.0
HKD1_k127_1053770_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.655e-235 736.0
HKD1_k127_1053770_2 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 9.867e-200 630.0
HKD1_k127_1053770_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 513.0
HKD1_k127_1053770_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 377.0
HKD1_k127_1053770_5 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
HKD1_k127_1053770_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 313.0
HKD1_k127_1053770_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000001463 158.0
HKD1_k127_1058378_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 5.291e-254 787.0
HKD1_k127_1058378_1 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 431.0
HKD1_k127_1058378_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
HKD1_k127_1058378_3 isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 321.0
HKD1_k127_1058378_5 transposase activity - - - 0.000000000000000000000000000000000003785 149.0
HKD1_k127_1058378_7 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000062 100.0
HKD1_k127_1058378_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000003758 65.0
HKD1_k127_1060912_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 467.0
HKD1_k127_1060912_1 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 479.0
HKD1_k127_1060912_2 PFAM secretion protein HlyD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 431.0
HKD1_k127_1060912_3 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 412.0
HKD1_k127_1060912_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000006837 178.0
HKD1_k127_1060912_6 efflux transmembrane transporter activity K02004 - - 0.00000000000000006891 93.0
HKD1_k127_1060912_7 transport, permease protein K09690 - - 0.00000000009686 72.0
HKD1_k127_1064637_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1746.0
HKD1_k127_1064637_1 Amidohydrolase family - - - 2.779e-265 824.0
HKD1_k127_1064637_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 428.0
HKD1_k127_1064637_11 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 419.0
HKD1_k127_1064637_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 387.0
HKD1_k127_1064637_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 330.0
HKD1_k127_1064637_14 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000001367 207.0
HKD1_k127_1064637_15 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000843 90.0
HKD1_k127_1064637_16 - - - - 0.000000000000000001638 92.0
HKD1_k127_1064637_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 4.693e-219 682.0
HKD1_k127_1064637_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.198e-215 677.0
HKD1_k127_1064637_4 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.079e-204 642.0
HKD1_k127_1064637_5 Fusaric acid resistance protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 563.0
HKD1_k127_1064637_6 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 538.0
HKD1_k127_1064637_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 492.0
HKD1_k127_1064637_8 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 498.0
HKD1_k127_1064637_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 448.0
HKD1_k127_1071064_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 532.0
HKD1_k127_1071064_1 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 449.0
HKD1_k127_1071064_2 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006537 269.0
HKD1_k127_1071064_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000009599 205.0
HKD1_k127_1071064_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000005422 86.0
HKD1_k127_1077161_0 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 477.0
HKD1_k127_1077161_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 430.0
HKD1_k127_1077161_2 Putative vitamin uptake transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 302.0
HKD1_k127_1077161_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002405 243.0
HKD1_k127_1077161_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000006653 194.0
HKD1_k127_1077362_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0 1583.0
HKD1_k127_1077362_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.507e-280 873.0
HKD1_k127_1077362_10 Peptidase family S49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 398.0
HKD1_k127_1077362_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 361.0
HKD1_k127_1077362_12 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
HKD1_k127_1077362_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 346.0
HKD1_k127_1077362_14 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 299.0
HKD1_k127_1077362_15 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003721 279.0
HKD1_k127_1077362_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HKD1_k127_1077362_17 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000000007605 217.0
HKD1_k127_1077362_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.156e-226 710.0
HKD1_k127_1077362_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 4.454e-215 674.0
HKD1_k127_1077362_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 1.311e-196 616.0
HKD1_k127_1077362_5 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 601.0
HKD1_k127_1077362_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 547.0
HKD1_k127_1077362_7 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 543.0
HKD1_k127_1077362_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 517.0
HKD1_k127_1077362_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 448.0
HKD1_k127_1077712_0 Amidohydrolase family - - - 1.057e-318 981.0
HKD1_k127_1077712_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 3.795e-304 949.0
HKD1_k127_1077712_10 Acetyl-CoA hydrolase/transferase C-terminal domain K18288,K22214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 586.0
HKD1_k127_1077712_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 513.0
HKD1_k127_1077712_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 478.0
HKD1_k127_1077712_13 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 461.0
HKD1_k127_1077712_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 473.0
HKD1_k127_1077712_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 471.0
HKD1_k127_1077712_16 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD1_k127_1077712_17 COG0477 Permeases of the major facilitator superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 421.0
HKD1_k127_1077712_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 407.0
HKD1_k127_1077712_19 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 400.0
HKD1_k127_1077712_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.09e-298 924.0
HKD1_k127_1077712_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 387.0
HKD1_k127_1077712_21 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 386.0
HKD1_k127_1077712_22 Belongs to the HpcH HpaI aldolase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 323.0
HKD1_k127_1077712_23 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 316.0
HKD1_k127_1077712_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 289.0
HKD1_k127_1077712_25 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 295.0
HKD1_k127_1077712_26 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000288 258.0
HKD1_k127_1077712_27 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001879 226.0
HKD1_k127_1077712_28 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
HKD1_k127_1077712_29 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.0000000000000000000000000000000000000000000000000000005028 193.0
HKD1_k127_1077712_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.297e-287 887.0
HKD1_k127_1077712_30 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000000000000000000003933 179.0
HKD1_k127_1077712_31 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000007168 149.0
HKD1_k127_1077712_32 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000006892 139.0
HKD1_k127_1077712_34 - - - - 0.0000000000000000000000000000000001259 141.0
HKD1_k127_1077712_35 Mannose-6-phosphate isomerase - - - 0.000000001591 65.0
HKD1_k127_1077712_37 nucleotidyltransferase activity K00984 - 2.7.7.47 0.000001741 53.0
HKD1_k127_1077712_4 Adenylate cyclase K01768 - 4.6.1.1 5.588e-248 777.0
HKD1_k127_1077712_5 PFAM amidohydrolase K07045 - - 4.097e-247 764.0
HKD1_k127_1077712_6 Belongs to the DEAD box helicase family - - - 3.523e-233 728.0
HKD1_k127_1077712_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.253e-231 746.0
HKD1_k127_1077712_8 Mate efflux family protein - - - 2.826e-222 698.0
HKD1_k127_1077712_9 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 1.439e-201 635.0
HKD1_k127_1084996_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.872e-280 871.0
HKD1_k127_1084996_1 Bacterial extracellular solute-binding protein K02027 - - 1.689e-260 808.0
HKD1_k127_1084996_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 538.0
HKD1_k127_1084996_11 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 525.0
HKD1_k127_1084996_12 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 500.0
HKD1_k127_1084996_13 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 430.0
HKD1_k127_1084996_15 Chitinase class I K03791 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 318.0
HKD1_k127_1084996_16 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
HKD1_k127_1084996_17 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
HKD1_k127_1084996_19 DoxX K15977 - - 0.000000000000000000000000000000000000000000007353 167.0
HKD1_k127_1084996_2 Gamma-glutamyltranspeptidase - - - 3.375e-258 804.0
HKD1_k127_1084996_20 - - - - 0.0000000000000000000003781 98.0
HKD1_k127_1084996_23 PFAM CBS domain containing protein - - - 0.000000000000001391 81.0
HKD1_k127_1084996_24 Bacterial extracellular solute-binding protein K02027 - - 0.0005102 43.0
HKD1_k127_1084996_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.57e-214 670.0
HKD1_k127_1084996_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 1.601e-209 654.0
HKD1_k127_1084996_5 Luciferase-like monooxygenase K04091 - 1.14.14.5 5.945e-202 663.0
HKD1_k127_1084996_6 Protein of unknown function (DUF1214) - - - 2.216e-197 624.0
HKD1_k127_1084996_7 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 592.0
HKD1_k127_1084996_8 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 548.0
HKD1_k127_1084996_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 541.0
HKD1_k127_1104861_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1055.0
HKD1_k127_1104861_1 A circularly permuted ATPgrasp - - - 5.081e-281 889.0
HKD1_k127_1104861_10 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 439.0
HKD1_k127_1104861_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 304.0
HKD1_k127_1104861_12 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
HKD1_k127_1104861_13 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002384 237.0
HKD1_k127_1104861_14 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000000000000000000000000001108 217.0
HKD1_k127_1104861_15 type II secretion system protein E K02283,K20527 - - 0.0000000000000003779 91.0
HKD1_k127_1104861_16 COG3209 Rhs family protein - - - 0.000000000007478 72.0
HKD1_k127_1104861_2 Aminotransferase K00812 - 2.6.1.1 5.124e-225 703.0
HKD1_k127_1104861_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 550.0
HKD1_k127_1104861_4 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 572.0
HKD1_k127_1104861_5 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 555.0
HKD1_k127_1104861_6 cytochrome c oxidase K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 532.0
HKD1_k127_1104861_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 507.0
HKD1_k127_1104861_8 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 498.0
HKD1_k127_1104861_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 443.0
HKD1_k127_1134620_0 COG3170 Tfp pilus assembly protein FimV K08086 - - 2.01e-206 664.0
HKD1_k127_1134620_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000007961 68.0
HKD1_k127_114627_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 599.0
HKD1_k127_114627_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000026 261.0
HKD1_k127_1149440_0 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 0.0 1113.0
HKD1_k127_1149440_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.833e-220 687.0
HKD1_k127_1149440_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 333.0
HKD1_k127_1149440_11 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 319.0
HKD1_k127_1149440_12 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004526 279.0
HKD1_k127_1149440_13 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000014 241.0
HKD1_k127_1149440_14 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000005078 228.0
HKD1_k127_1149440_15 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
HKD1_k127_1149440_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000003493 122.0
HKD1_k127_1149440_17 Belongs to the ompA family - - - 0.000000000007478 72.0
HKD1_k127_1149440_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 577.0
HKD1_k127_1149440_3 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 556.0
HKD1_k127_1149440_4 fatty acid alpha-oxidation K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 520.0
HKD1_k127_1149440_5 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 489.0
HKD1_k127_1149440_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 466.0
HKD1_k127_1149440_7 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 449.0
HKD1_k127_1149440_8 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 389.0
HKD1_k127_1149440_9 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 383.0
HKD1_k127_1178917_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1051.0
HKD1_k127_1178917_1 NADH-ubiquinone oxidoreductase chain 49kDa - - - 1.177e-246 769.0
HKD1_k127_1178917_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 385.0
HKD1_k127_1178917_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 395.0
HKD1_k127_1178917_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 372.0
HKD1_k127_1178917_13 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 355.0
HKD1_k127_1178917_14 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002519 249.0
HKD1_k127_1178917_15 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005265 239.0
HKD1_k127_1178917_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000000000000000000000000000000000000000003003 205.0
HKD1_k127_1178917_17 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000000000000000000000000000001065 208.0
HKD1_k127_1178917_18 oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000001691 196.0
HKD1_k127_1178917_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000000000001162 140.0
HKD1_k127_1178917_2 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 9.928e-224 698.0
HKD1_k127_1178917_22 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000008331 95.0
HKD1_k127_1178917_23 Pentapeptide repeats (9 copies) - - - 0.0000000000000009615 83.0
HKD1_k127_1178917_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 9.361e-200 625.0
HKD1_k127_1178917_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 561.0
HKD1_k127_1178917_5 restriction endodeoxyribonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 511.0
HKD1_k127_1178917_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 516.0
HKD1_k127_1178917_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 475.0
HKD1_k127_1178917_8 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
HKD1_k127_1178917_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 385.0
HKD1_k127_1187021_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.38e-253 787.0
HKD1_k127_1187021_1 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 590.0
HKD1_k127_1187021_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 406.0
HKD1_k127_1187021_11 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 389.0
HKD1_k127_1187021_12 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 324.0
HKD1_k127_1187021_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
HKD1_k127_1187021_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
HKD1_k127_1187021_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006594 230.0
HKD1_k127_1187021_16 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000009909 220.0
HKD1_k127_1187021_17 AIG2-like family - - - 0.000000000000000000000000000000000000000000000000000000000025 211.0
HKD1_k127_1187021_18 carbonate dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000001889 203.0
HKD1_k127_1187021_19 Domain of unknown function (DUF1476) - - - 0.00000000000000000000000000000000000000001125 155.0
HKD1_k127_1187021_2 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 571.0
HKD1_k127_1187021_20 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000004161 148.0
HKD1_k127_1187021_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 550.0
HKD1_k127_1187021_4 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 511.0
HKD1_k127_1187021_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 489.0
HKD1_k127_1187021_6 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 484.0
HKD1_k127_1187021_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 453.0
HKD1_k127_1187021_8 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 434.0
HKD1_k127_1187021_9 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 429.0
HKD1_k127_1251218_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 2.668e-305 939.0
HKD1_k127_1251218_1 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 1.349e-219 684.0
HKD1_k127_1251218_10 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004083 224.0
HKD1_k127_1251218_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000000000000000007814 223.0
HKD1_k127_1251218_13 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000001425 164.0
HKD1_k127_1251218_15 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000004458 63.0
HKD1_k127_1251218_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 589.0
HKD1_k127_1251218_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 516.0
HKD1_k127_1251218_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 511.0
HKD1_k127_1251218_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 490.0
HKD1_k127_1251218_6 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 438.0
HKD1_k127_1251218_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 362.0
HKD1_k127_1251218_8 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 304.0
HKD1_k127_1251218_9 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003451 287.0
HKD1_k127_1304966_0 Glycosyl transferase family group 2 - - - 0.0 1712.0
HKD1_k127_1304966_1 AMP-binding enzyme C-terminal domain K01895,K08295 - 6.2.1.1,6.2.1.32 1.42e-253 814.0
HKD1_k127_1304966_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
HKD1_k127_1304966_11 Rieske (2fe-2S) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 372.0
HKD1_k127_1304966_12 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
HKD1_k127_1304966_13 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
HKD1_k127_1304966_14 Protein tyrosine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 322.0
HKD1_k127_1304966_15 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 322.0
HKD1_k127_1304966_16 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HKD1_k127_1304966_17 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007575 270.0
HKD1_k127_1304966_18 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 274.0
HKD1_k127_1304966_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 5.892e-211 675.0
HKD1_k127_1304966_20 - - - - 0.000000000000000000000000000000000000000000000001119 179.0
HKD1_k127_1304966_21 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.0000000000000000000000000000000000001697 157.0
HKD1_k127_1304966_22 Toprim domain K06919 - - 0.0000000000000000000000000000000000002303 152.0
HKD1_k127_1304966_23 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000005762 134.0
HKD1_k127_1304966_24 glycogen (starch) synthase activity - - - 0.0000000000000000000004931 109.0
HKD1_k127_1304966_25 AAA domain - - - 0.000000000000000001115 91.0
HKD1_k127_1304966_26 MaoC like domain - - - 0.0000000000000000542 81.0
HKD1_k127_1304966_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 476.0
HKD1_k127_1304966_4 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 469.0
HKD1_k127_1304966_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 470.0
HKD1_k127_1304966_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 462.0
HKD1_k127_1304966_7 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 452.0
HKD1_k127_1304966_8 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 429.0
HKD1_k127_1304966_9 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 415.0
HKD1_k127_1326658_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0 1180.0
HKD1_k127_1326658_1 Serine/threonine phosphatases, family 2C, catalytic domain - - - 1.069e-259 811.0
HKD1_k127_1326658_2 Formate/nitrite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 477.0
HKD1_k127_1326658_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 416.0
HKD1_k127_1326658_4 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 353.0
HKD1_k127_1326658_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000003712 233.0
HKD1_k127_1326658_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD1_k127_1326658_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000002526 187.0
HKD1_k127_1326658_8 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000000000000000002567 172.0
HKD1_k127_1326658_9 Bacterial protein of unknown function (DUF839) K07093 - - 0.000009778 56.0
HKD1_k127_134217_0 ATPase family associated with various cellular activities (AAA) K03924 - - 2.571e-194 611.0
HKD1_k127_134217_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 494.0
HKD1_k127_134217_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 287.0
HKD1_k127_134217_4 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000004968 119.0
HKD1_k127_134217_5 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000006619 112.0
HKD1_k127_1351838_0 Enoyl-CoA hydratase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 1.521e-230 721.0
HKD1_k127_1351838_1 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 9.059e-222 703.0
HKD1_k127_1351838_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 524.0
HKD1_k127_1351838_11 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 488.0
HKD1_k127_1351838_12 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 503.0
HKD1_k127_1351838_13 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 413.0
HKD1_k127_1351838_14 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 377.0
HKD1_k127_1351838_15 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 362.0
HKD1_k127_1351838_16 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 264.0
HKD1_k127_1351838_17 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001949 256.0
HKD1_k127_1351838_18 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000001619 217.0
HKD1_k127_1351838_19 - - - - 0.0000000000000000000000000000000000000000000000000001533 199.0
HKD1_k127_1351838_2 COG1960 Acyl-CoA dehydrogenases - - - 1.056e-215 674.0
HKD1_k127_1351838_20 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000001784 151.0
HKD1_k127_1351838_21 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000003204 125.0
HKD1_k127_1351838_22 AraC-like ligand binding domain - - - 0.000000000000000000000002371 106.0
HKD1_k127_1351838_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000002947 84.0
HKD1_k127_1351838_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 3.613e-209 653.0
HKD1_k127_1351838_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 2.46e-204 642.0
HKD1_k127_1351838_5 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 604.0
HKD1_k127_1351838_6 GntP family permease K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 589.0
HKD1_k127_1351838_7 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 582.0
HKD1_k127_1351838_8 Belongs to the proline racemase family K01777 - 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 574.0
HKD1_k127_1351838_9 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 512.0
HKD1_k127_1371586_0 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 517.0
HKD1_k127_1371586_1 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 395.0
HKD1_k127_1371586_2 polar amino acid transport system K02028 - 3.6.3.21 0.000000000000000000000000000000001018 130.0
HKD1_k127_1417279_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.087e-261 811.0
HKD1_k127_1417279_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 4.313e-259 805.0
HKD1_k127_1417279_10 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 386.0
HKD1_k127_1417279_11 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 369.0
HKD1_k127_1417279_12 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 366.0
HKD1_k127_1417279_13 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 325.0
HKD1_k127_1417279_14 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HKD1_k127_1417279_15 regulatory protein K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000006441 259.0
HKD1_k127_1417279_16 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007311 236.0
HKD1_k127_1417279_17 - - - - 0.0000000000000000000000000000000000000000000000000000000001024 211.0
HKD1_k127_1417279_18 - - - - 0.000000000000000000000000000000000000000000000000001552 204.0
HKD1_k127_1417279_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.059e-247 771.0
HKD1_k127_1417279_20 - - - - 0.00000000000000000000001278 101.0
HKD1_k127_1417279_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 5.083e-208 649.0
HKD1_k127_1417279_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.025e-202 643.0
HKD1_k127_1417279_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 576.0
HKD1_k127_1417279_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 539.0
HKD1_k127_1417279_7 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 532.0
HKD1_k127_1417279_8 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 496.0
HKD1_k127_1417279_9 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 421.0
HKD1_k127_1476276_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 531.0
HKD1_k127_1476276_1 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002728 252.0
HKD1_k127_1476276_2 transposable element conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
HKD1_k127_1476276_3 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000004129 175.0
HKD1_k127_1476276_4 helix_turn_helix, mercury resistance K08365 - - 0.000000000000000000000000000000000003007 148.0
HKD1_k127_1476276_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000002998 121.0
HKD1_k127_1476276_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000118 120.0
HKD1_k127_1476276_7 Transposase, Mutator family K07493 - - 0.00000000003562 71.0
HKD1_k127_1476276_8 MerT mercuric transport protein - - - 0.0000000007761 65.0
HKD1_k127_1487661_0 lysyl-tRNA synthetase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 585.0
HKD1_k127_1487661_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 346.0
HKD1_k127_1487661_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003274 263.0
HKD1_k127_1487661_3 YjbR - - - 0.00000000000000000000000000000000000000000000000001056 182.0
HKD1_k127_1487661_4 lipolytic protein G-D-S-L family - - - 0.0009708 51.0
HKD1_k127_1501410_0 Homospermidine synthase K00808 - 2.5.1.44 7.042e-264 817.0
HKD1_k127_1501410_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 453.0
HKD1_k127_1501410_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
HKD1_k127_1536331_0 malic enzyme K00029 - 1.1.1.40 0.0 1369.0
HKD1_k127_1536331_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1340.0
HKD1_k127_1536331_10 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 533.0
HKD1_k127_1536331_11 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 510.0
HKD1_k127_1536331_12 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 451.0
HKD1_k127_1536331_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 451.0
HKD1_k127_1536331_14 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 439.0
HKD1_k127_1536331_15 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 426.0
HKD1_k127_1536331_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 399.0
HKD1_k127_1536331_17 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 391.0
HKD1_k127_1536331_18 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 388.0
HKD1_k127_1536331_19 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 367.0
HKD1_k127_1536331_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1227.0
HKD1_k127_1536331_20 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 359.0
HKD1_k127_1536331_21 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 296.0
HKD1_k127_1536331_22 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HKD1_k127_1536331_23 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 280.0
HKD1_k127_1536331_24 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
HKD1_k127_1536331_25 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000000002731 239.0
HKD1_k127_1536331_26 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000439 215.0
HKD1_k127_1536331_27 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000008718 206.0
HKD1_k127_1536331_28 - - - - 0.00000000000000000000000000000000000000000000000001548 183.0
HKD1_k127_1536331_29 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000000000000000000003265 158.0
HKD1_k127_1536331_3 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.0 1129.0
HKD1_k127_1536331_30 transposase activity - - - 0.0000000000000000000000008107 120.0
HKD1_k127_1536331_4 AsmA family K07289,K07290 - - 0.0 1012.0
HKD1_k127_1536331_5 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 2.962e-317 974.0
HKD1_k127_1536331_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 5.91e-269 846.0
HKD1_k127_1536331_7 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 5.819e-245 760.0
HKD1_k127_1536331_8 Acts as a magnesium transporter K06213 - - 5.393e-218 711.0
HKD1_k127_1536331_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 541.0
HKD1_k127_1589223_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 533.0
HKD1_k127_1589223_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 522.0
HKD1_k127_1589223_2 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004896 281.0
HKD1_k127_1589223_3 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007492 228.0
HKD1_k127_1589223_4 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.00000000000000000000000000000000000000000000005121 173.0
HKD1_k127_1609869_0 Protein tyrosine kinase - - - 8.594e-194 614.0
HKD1_k127_1609869_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 465.0
HKD1_k127_1614728_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1076.0
HKD1_k127_1614728_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000009793 175.0
HKD1_k127_1645052_0 Histidine kinase - - - 0.0 1596.0
HKD1_k127_1645052_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 1.747e-198 621.0
HKD1_k127_1645052_10 - - - - 0.00000003281 68.0
HKD1_k127_1645052_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 554.0
HKD1_k127_1645052_3 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 486.0
HKD1_k127_1645052_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 457.0
HKD1_k127_1645052_5 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 429.0
HKD1_k127_1645052_6 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 336.0
HKD1_k127_1645052_7 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
HKD1_k127_1645052_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001576 280.0
HKD1_k127_1665296_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 438.0
HKD1_k127_1665296_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 439.0
HKD1_k127_1665296_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 449.0
HKD1_k127_1665296_3 Exodeoxyribonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
HKD1_k127_167517_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0 1558.0
HKD1_k127_167517_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.439e-296 925.0
HKD1_k127_167517_10 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 547.0
HKD1_k127_167517_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 547.0
HKD1_k127_167517_12 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 530.0
HKD1_k127_167517_13 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 522.0
HKD1_k127_167517_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 518.0
HKD1_k127_167517_15 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 506.0
HKD1_k127_167517_16 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 505.0
HKD1_k127_167517_17 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 488.0
HKD1_k127_167517_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 504.0
HKD1_k127_167517_19 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 484.0
HKD1_k127_167517_2 AMP-binding enzyme C-terminal domain - - - 2.453e-280 867.0
HKD1_k127_167517_20 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 483.0
HKD1_k127_167517_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 458.0
HKD1_k127_167517_22 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 416.0
HKD1_k127_167517_23 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 379.0
HKD1_k127_167517_24 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 363.0
HKD1_k127_167517_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 326.0
HKD1_k127_167517_27 HD phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 316.0
HKD1_k127_167517_29 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005197 274.0
HKD1_k127_167517_3 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 7.169e-248 769.0
HKD1_k127_167517_31 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004922 248.0
HKD1_k127_167517_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 238.0
HKD1_k127_167517_33 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002314 238.0
HKD1_k127_167517_34 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005278 228.0
HKD1_k127_167517_35 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
HKD1_k127_167517_36 - - - - 0.00000000000000000000000000000000000000000001555 162.0
HKD1_k127_167517_37 YGGT family K02221 - - 0.0000000000000000000000000000000002082 133.0
HKD1_k127_167517_38 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000007033 109.0
HKD1_k127_167517_4 P-aminobenzoate N-oxygenase AurF - - - 7.919e-222 690.0
HKD1_k127_167517_40 - - - - 0.0000000000005727 72.0
HKD1_k127_167517_41 phosphatase activity K05967 - - 0.0000000005909 65.0
HKD1_k127_167517_42 SOS response associated peptidase (SRAP) - - - 0.000000037 61.0
HKD1_k127_167517_45 self proteolysis - - - 0.00009136 53.0
HKD1_k127_167517_46 SOS response associated peptidase (SRAP) - - - 0.000111 51.0
HKD1_k127_167517_5 P-aminobenzoate N-oxygenase AurF - - - 7.307e-211 659.0
HKD1_k127_167517_6 Receptor family ligand binding region - - - 1.132e-208 655.0
HKD1_k127_167517_7 Oxidoreductase NAD-binding domain K21832 - - 3.023e-197 620.0
HKD1_k127_167517_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 620.0
HKD1_k127_167517_9 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 563.0
HKD1_k127_1682030_0 NAD synthase K01950 - 6.3.5.1 0.0 1188.0
HKD1_k127_1682030_1 Amidohydrolase family K01461 - 3.5.1.82 4.396e-297 914.0
HKD1_k127_1682030_10 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 558.0
HKD1_k127_1682030_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 468.0
HKD1_k127_1682030_12 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 465.0
HKD1_k127_1682030_13 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 456.0
HKD1_k127_1682030_14 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 444.0
HKD1_k127_1682030_15 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
HKD1_k127_1682030_16 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 408.0
HKD1_k127_1682030_18 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 332.0
HKD1_k127_1682030_19 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K21395 GO:0003674,GO:0005488,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0030246,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 321.0
HKD1_k127_1682030_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.275e-291 901.0
HKD1_k127_1682030_20 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 310.0
HKD1_k127_1682030_21 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 292.0
HKD1_k127_1682030_22 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003857 271.0
HKD1_k127_1682030_23 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003507 259.0
HKD1_k127_1682030_24 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009775 256.0
HKD1_k127_1682030_25 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
HKD1_k127_1682030_26 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007528 243.0
HKD1_k127_1682030_27 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000002441 231.0
HKD1_k127_1682030_28 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005803 242.0
HKD1_k127_1682030_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 9.076e-286 882.0
HKD1_k127_1682030_30 TspO MBR family protein K05770 - - 0.0000000000000000000000000000000000000001124 166.0
HKD1_k127_1682030_31 - K09712,K14475 - - 0.0000000000000000000000000000000000000001253 154.0
HKD1_k127_1682030_33 integral membrane protein - - - 0.0000000000000000000000000000000001694 134.0
HKD1_k127_1682030_34 Transposase IS200 like K07491 - - 0.0000000000000000001745 91.0
HKD1_k127_1682030_35 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0004293 44.0
HKD1_k127_1682030_4 AMP-binding enzyme C-terminal domain - - - 3.272e-263 817.0
HKD1_k127_1682030_5 Protein of unknown function (DUF1800) - - - 4.917e-248 775.0
HKD1_k127_1682030_6 Major Facilitator Superfamily - - - 1.458e-227 722.0
HKD1_k127_1682030_7 Major facilitator superfamily - - - 1.152e-201 643.0
HKD1_k127_1682030_8 Protein of unknown function (DUF1501) - - - 4.267e-197 617.0
HKD1_k127_1682030_9 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 578.0
HKD1_k127_1683675_0 Radical SAM superfamily K11779 - 2.5.1.77 0.0 1322.0
HKD1_k127_1683675_1 Acyl-CoA dehydrogenase, middle domain - - - 2.536e-245 767.0
HKD1_k127_1683675_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 477.0
HKD1_k127_1683675_11 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 459.0
HKD1_k127_1683675_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 418.0
HKD1_k127_1683675_13 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 374.0
HKD1_k127_1683675_14 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 363.0
HKD1_k127_1683675_15 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 344.0
HKD1_k127_1683675_16 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 316.0
HKD1_k127_1683675_17 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 276.0
HKD1_k127_1683675_18 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000003145 243.0
HKD1_k127_1683675_19 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
HKD1_k127_1683675_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 4.451e-195 614.0
HKD1_k127_1683675_20 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000002982 205.0
HKD1_k127_1683675_21 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000006119 172.0
HKD1_k127_1683675_22 - - - - 0.00000000000000000000000000191 116.0
HKD1_k127_1683675_23 gluconolactonase activity K14274 - - 0.0000000000000003361 83.0
HKD1_k127_1683675_3 Luciferase-like monooxygenase - - - 2.532e-194 609.0
HKD1_k127_1683675_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 567.0
HKD1_k127_1683675_5 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 492.0
HKD1_k127_1683675_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 484.0
HKD1_k127_1683675_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
HKD1_k127_1683675_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 471.0
HKD1_k127_1683675_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 468.0
HKD1_k127_1716401_0 Binding-protein-dependent transport system inner membrane component - - - 0.0 1018.0
HKD1_k127_1716401_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.053e-310 954.0
HKD1_k127_1716401_10 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000006276 110.0
HKD1_k127_1716401_2 Bacterial extracellular solute-binding protein - - - 9.288e-194 607.0
HKD1_k127_1716401_3 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 603.0
HKD1_k127_1716401_4 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 568.0
HKD1_k127_1716401_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 527.0
HKD1_k127_1716401_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 496.0
HKD1_k127_1716401_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 523.0
HKD1_k127_1716401_8 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009309 271.0
HKD1_k127_1716401_9 ABC-type nitrate sulfonate bicarbonate transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000005217 232.0
HKD1_k127_1745395_0 Bacterial extracellular solute-binding protein K02027 - - 3.357e-266 825.0
HKD1_k127_1745395_1 Beta-lactamase - - - 7.403e-238 738.0
HKD1_k127_1745395_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000006114 198.0
HKD1_k127_1745395_11 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000003371 198.0
HKD1_k127_1745395_2 Amidase K02433 - 6.3.5.6,6.3.5.7 6.944e-228 715.0
HKD1_k127_1745395_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 573.0
HKD1_k127_1745395_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 552.0
HKD1_k127_1745395_5 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 536.0
HKD1_k127_1745395_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 501.0
HKD1_k127_1745395_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 366.0
HKD1_k127_1745395_8 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
HKD1_k127_1745395_9 PFAM NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001231 224.0
HKD1_k127_1750313_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.574e-254 786.0
HKD1_k127_1750313_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 325.0
HKD1_k127_1750313_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
HKD1_k127_1750313_3 Cytochrome C1 family K00413 - - 0.000000002365 59.0
HKD1_k127_1762193_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1421.0
HKD1_k127_1762193_1 Sulfite reductase K00381 - 1.8.1.2 0.0 1007.0
HKD1_k127_1762193_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 563.0
HKD1_k127_1762193_11 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 558.0
HKD1_k127_1762193_12 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 541.0
HKD1_k127_1762193_13 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 548.0
HKD1_k127_1762193_14 16S RNA G1207 methylase RsmC K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 482.0
HKD1_k127_1762193_15 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 443.0
HKD1_k127_1762193_16 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 426.0
HKD1_k127_1762193_17 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
HKD1_k127_1762193_18 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 425.0
HKD1_k127_1762193_19 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
HKD1_k127_1762193_2 Acetolactate synthase K01576,K01652 GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6,4.1.1.7 2.052e-274 878.0
HKD1_k127_1762193_20 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 415.0
HKD1_k127_1762193_21 Inosine-uridine preferring nucleoside hydrolase K12700 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 394.0
HKD1_k127_1762193_22 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 409.0
HKD1_k127_1762193_23 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 385.0
HKD1_k127_1762193_24 branched-chain amino acid K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 356.0
HKD1_k127_1762193_25 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
HKD1_k127_1762193_26 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 296.0
HKD1_k127_1762193_27 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
HKD1_k127_1762193_28 Hsp20/alpha crystallin family K04080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001321 262.0
HKD1_k127_1762193_29 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003847 251.0
HKD1_k127_1762193_3 - - - - 3.058e-223 699.0
HKD1_k127_1762193_30 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003861 233.0
HKD1_k127_1762193_31 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
HKD1_k127_1762193_32 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000001865 186.0
HKD1_k127_1762193_33 FCD - - - 0.00000000000000000000000000000000000000000000000001174 198.0
HKD1_k127_1762193_34 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000004721 176.0
HKD1_k127_1762193_35 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000003283 171.0
HKD1_k127_1762193_36 - - - - 0.00000000000000000000000000000001715 138.0
HKD1_k127_1762193_37 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000008066 128.0
HKD1_k127_1762193_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000001537 88.0
HKD1_k127_1762193_39 Protein of unknown function (DUF2849) - - - 0.000000008008 64.0
HKD1_k127_1762193_4 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 1.091e-212 663.0
HKD1_k127_1762193_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 2.948e-210 663.0
HKD1_k127_1762193_6 AlkA N-terminal domain K13529 - 3.2.2.21 8.731e-197 616.0
HKD1_k127_1762193_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 599.0
HKD1_k127_1762193_8 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 611.0
HKD1_k127_1762193_9 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 606.0
HKD1_k127_1853890_0 Pyridine nucleotide-disulphide oxidoreductase - - - 9.869e-211 665.0
HKD1_k127_1853890_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 626.0
HKD1_k127_1853890_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
HKD1_k127_1853890_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000005354 157.0
HKD1_k127_1853890_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000004661 146.0
HKD1_k127_1853890_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000001729 139.0
HKD1_k127_1853890_14 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000001589 105.0
HKD1_k127_1853890_2 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 553.0
HKD1_k127_1853890_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 480.0
HKD1_k127_1853890_4 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 473.0
HKD1_k127_1853890_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 377.0
HKD1_k127_1853890_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 323.0
HKD1_k127_1853890_7 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 342.0
HKD1_k127_1853890_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
HKD1_k127_1853890_9 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000006355 226.0
HKD1_k127_1874914_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.77e-286 892.0
HKD1_k127_1874914_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.148e-273 846.0
HKD1_k127_1874914_10 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 422.0
HKD1_k127_1874914_11 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 396.0
HKD1_k127_1874914_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 385.0
HKD1_k127_1874914_13 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
HKD1_k127_1874914_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
HKD1_k127_1874914_15 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 355.0
HKD1_k127_1874914_16 myo-inosose-2 dehydratase activity K01805,K19974 - 5.1.3.35,5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 346.0
HKD1_k127_1874914_17 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 308.0
HKD1_k127_1874914_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 299.0
HKD1_k127_1874914_19 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
HKD1_k127_1874914_2 Bacterial protein of unknown function (DUF853) K06915 - - 1.24e-254 801.0
HKD1_k127_1874914_20 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004016 270.0
HKD1_k127_1874914_21 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002918 261.0
HKD1_k127_1874914_22 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
HKD1_k127_1874914_23 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000004489 223.0
HKD1_k127_1874914_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000002462 201.0
HKD1_k127_1874914_25 Heavy-metal resistance - - - 0.000000000000000000000000000000000000000000000000002503 194.0
HKD1_k127_1874914_26 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000000000003656 184.0
HKD1_k127_1874914_27 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000002479 150.0
HKD1_k127_1874914_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.375e-206 649.0
HKD1_k127_1874914_4 His Kinase A (phosphoacceptor) domain - - - 5.24e-200 633.0
HKD1_k127_1874914_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 539.0
HKD1_k127_1874914_6 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 518.0
HKD1_k127_1874914_7 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 509.0
HKD1_k127_1874914_8 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 494.0
HKD1_k127_1874914_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 456.0
HKD1_k127_191079_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1048.0
HKD1_k127_191079_1 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 529.0
HKD1_k127_191079_2 Thymidine phosphorylase K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 475.0
HKD1_k127_191079_3 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
HKD1_k127_191079_4 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 331.0
HKD1_k127_191079_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007079 284.0
HKD1_k127_191079_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002034 265.0
HKD1_k127_1911419_0 Domain of unknown function (DUF4175) - - - 0.0 1437.0
HKD1_k127_1911419_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1368.0
HKD1_k127_1911419_10 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 555.0
HKD1_k127_1911419_11 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 555.0
HKD1_k127_1911419_12 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 554.0
HKD1_k127_1911419_13 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 537.0
HKD1_k127_1911419_14 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 520.0
HKD1_k127_1911419_15 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 495.0
HKD1_k127_1911419_16 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 457.0
HKD1_k127_1911419_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 444.0
HKD1_k127_1911419_18 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 387.0
HKD1_k127_1911419_19 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 342.0
HKD1_k127_1911419_2 Sulfatase K01130 - 3.1.6.1 3.469e-318 995.0
HKD1_k127_1911419_20 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 307.0
HKD1_k127_1911419_21 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003062 272.0
HKD1_k127_1911419_22 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
HKD1_k127_1911419_23 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001541 261.0
HKD1_k127_1911419_24 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003108 239.0
HKD1_k127_1911419_25 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001174 214.0
HKD1_k127_1911419_26 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000001303 194.0
HKD1_k127_1911419_27 - - - - 0.00000000000000000000000000000000000000000000000000004069 192.0
HKD1_k127_1911419_3 argininosuccinate lyase K01755 - 4.3.2.1 2.74e-269 833.0
HKD1_k127_1911419_4 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 3.404e-260 805.0
HKD1_k127_1911419_5 L,D-transpeptidase catalytic domain K21470 - - 4.67e-244 761.0
HKD1_k127_1911419_6 amine oxidase K00274 - 1.4.3.4 4.957e-242 762.0
HKD1_k127_1911419_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 5.34e-229 742.0
HKD1_k127_1911419_8 Belongs to the peptidase S1C family - - - 9.879e-228 712.0
HKD1_k127_1911419_9 FAD binding domain - - - 1.334e-203 647.0
HKD1_k127_191323_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1716.0
HKD1_k127_191323_1 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 0.0 1682.0
HKD1_k127_191323_10 transcriptional regulator K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 328.0
HKD1_k127_191323_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 291.0
HKD1_k127_191323_12 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
HKD1_k127_191323_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000001987 215.0
HKD1_k127_191323_14 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.0000000000000000000000000000000000000005865 149.0
HKD1_k127_191323_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 5.475e-203 641.0
HKD1_k127_191323_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 9.141e-197 616.0
HKD1_k127_191323_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 7.674e-196 612.0
HKD1_k127_191323_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 584.0
HKD1_k127_191323_6 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 481.0
HKD1_k127_191323_7 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 481.0
HKD1_k127_191323_8 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 447.0
HKD1_k127_191323_9 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 370.0
HKD1_k127_191884_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1169.0
HKD1_k127_191884_1 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0 1141.0
HKD1_k127_191884_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 381.0
HKD1_k127_191884_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 325.0
HKD1_k127_191884_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000005328 123.0
HKD1_k127_191884_13 - - - - 0.00000000008636 72.0
HKD1_k127_191884_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.195e-306 957.0
HKD1_k127_191884_3 Receptor family ligand binding region - - - 1.425e-242 755.0
HKD1_k127_191884_4 Major Facilitator Superfamily - - - 6.272e-214 668.0
HKD1_k127_191884_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 511.0
HKD1_k127_191884_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 454.0
HKD1_k127_191884_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 436.0
HKD1_k127_191884_8 PFAM Deoxyribonuclease II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 400.0
HKD1_k127_191884_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 399.0
HKD1_k127_1943402_0 acid transport system permease K09970 - - 1.277e-223 696.0
HKD1_k127_1943402_1 general L-amino acid-binding periplasmic protein AapJ K09969 - - 7.294e-200 627.0
HKD1_k127_1943402_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 566.0
HKD1_k127_1943402_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 404.0
HKD1_k127_1943402_4 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 388.0
HKD1_k127_1943402_5 acid transport K09972 - - 0.00000000000000000000000000001635 121.0
HKD1_k127_1960132_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1996.0
HKD1_k127_1960132_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0 1087.0
HKD1_k127_1960132_10 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 551.0
HKD1_k127_1960132_11 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 536.0
HKD1_k127_1960132_12 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 475.0
HKD1_k127_1960132_13 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 439.0
HKD1_k127_1960132_14 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 436.0
HKD1_k127_1960132_15 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 450.0
HKD1_k127_1960132_16 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 402.0
HKD1_k127_1960132_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 353.0
HKD1_k127_1960132_18 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 326.0
HKD1_k127_1960132_19 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 300.0
HKD1_k127_1960132_2 Belongs to the TPP enzyme family K01577,K01652 - 2.2.1.6,4.1.1.8 0.0 1031.0
HKD1_k127_1960132_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007722 236.0
HKD1_k127_1960132_22 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000000005455 201.0
HKD1_k127_1960132_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001131 183.0
HKD1_k127_1960132_24 Transposase DDE domain - - - 0.00000000000000000000000000006595 116.0
HKD1_k127_1960132_25 Zinc-finger domain - - - 0.0000000000000000002031 91.0
HKD1_k127_1960132_26 ABC transporter transmembrane region K06147 - - 0.000000000000006969 89.0
HKD1_k127_1960132_27 COG3210 Large exoproteins involved in heme utilization or adhesion K15125 - - 0.00000000000009667 84.0
HKD1_k127_1960132_28 - - - - 0.00000000148 63.0
HKD1_k127_1960132_29 - - - - 0.00007233 49.0
HKD1_k127_1960132_3 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 5.648e-296 915.0
HKD1_k127_1960132_30 COG3209 Rhs family protein - - - 0.00009039 52.0
HKD1_k127_1960132_4 COG0457 FOG TPR repeat - - - 4.187e-291 909.0
HKD1_k127_1960132_5 Tripartite tricarboxylate transporter TctA family K07793 - - 5.87e-263 816.0
HKD1_k127_1960132_6 Urate oxidase N-terminal - - - 5.668e-234 726.0
HKD1_k127_1960132_7 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 4.277e-232 735.0
HKD1_k127_1960132_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 9.899e-204 640.0
HKD1_k127_1960132_9 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 573.0
HKD1_k127_2006010_0 mitochondrial gene expression - - - 0.0 1119.0
HKD1_k127_2006010_1 amine dehydrogenase activity - - - 0.0 1048.0
HKD1_k127_2006010_10 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 449.0
HKD1_k127_2006010_11 alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 430.0
HKD1_k127_2006010_12 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 408.0
HKD1_k127_2006010_13 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 378.0
HKD1_k127_2006010_14 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 375.0
HKD1_k127_2006010_15 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
HKD1_k127_2006010_16 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 360.0
HKD1_k127_2006010_17 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 357.0
HKD1_k127_2006010_18 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 322.0
HKD1_k127_2006010_19 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 298.0
HKD1_k127_2006010_2 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 5.513e-274 882.0
HKD1_k127_2006010_20 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 296.0
HKD1_k127_2006010_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 279.0
HKD1_k127_2006010_23 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
HKD1_k127_2006010_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002444 259.0
HKD1_k127_2006010_25 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000004337 253.0
HKD1_k127_2006010_26 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
HKD1_k127_2006010_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000005218 214.0
HKD1_k127_2006010_28 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
HKD1_k127_2006010_3 Sulfate permease family - - - 5.191e-211 669.0
HKD1_k127_2006010_30 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000323 209.0
HKD1_k127_2006010_31 Cupin domain - - - 0.0000000000000000000000000000000006561 141.0
HKD1_k127_2006010_32 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000003213 132.0
HKD1_k127_2006010_33 Redoxin - - - 0.0000000000009037 73.0
HKD1_k127_2006010_34 - - - - 0.0000000009924 64.0
HKD1_k127_2006010_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 588.0
HKD1_k127_2006010_5 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 576.0
HKD1_k127_2006010_6 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 542.0
HKD1_k127_2006010_7 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 468.0
HKD1_k127_2006010_8 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 468.0
HKD1_k127_2006010_9 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 448.0
HKD1_k127_2024607_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.507e-318 980.0
HKD1_k127_2024607_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 6.582e-318 983.0
HKD1_k127_2024607_10 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 595.0
HKD1_k127_2024607_11 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 567.0
HKD1_k127_2024607_12 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 548.0
HKD1_k127_2024607_13 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 505.0
HKD1_k127_2024607_14 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 524.0
HKD1_k127_2024607_15 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 499.0
HKD1_k127_2024607_16 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 462.0
HKD1_k127_2024607_17 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 451.0
HKD1_k127_2024607_18 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 453.0
HKD1_k127_2024607_19 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 423.0
HKD1_k127_2024607_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K14446 - 1.3.1.85 2.357e-285 878.0
HKD1_k127_2024607_20 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 397.0
HKD1_k127_2024607_21 Tetrapyrrole (Corrin/Porphyrin) Methylases K02228 - 2.1.1.152 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 398.0
HKD1_k127_2024607_22 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 385.0
HKD1_k127_2024607_23 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 372.0
HKD1_k127_2024607_24 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 361.0
HKD1_k127_2024607_25 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
HKD1_k127_2024607_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 359.0
HKD1_k127_2024607_27 Bile acid K14347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 344.0
HKD1_k127_2024607_28 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 332.0
HKD1_k127_2024607_29 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 315.0
HKD1_k127_2024607_3 Luciferase-like monooxygenase - - - 2.706e-285 876.0
HKD1_k127_2024607_30 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 298.0
HKD1_k127_2024607_31 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005253 286.0
HKD1_k127_2024607_32 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004262 266.0
HKD1_k127_2024607_33 belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003304 254.0
HKD1_k127_2024607_35 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000003333 225.0
HKD1_k127_2024607_36 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007168 221.0
HKD1_k127_2024607_37 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000001711 235.0
HKD1_k127_2024607_38 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000002646 187.0
HKD1_k127_2024607_39 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002372 182.0
HKD1_k127_2024607_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 2.193e-261 809.0
HKD1_k127_2024607_40 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000004866 162.0
HKD1_k127_2024607_42 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000001885 144.0
HKD1_k127_2024607_43 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000001373 140.0
HKD1_k127_2024607_44 GYD domain - - - 0.000000000000000000000000000000009087 129.0
HKD1_k127_2024607_45 Aha1 domain protein - - - 0.0000000000000000000000000000002584 128.0
HKD1_k127_2024607_46 - - - - 0.0000000000000000000000000009649 130.0
HKD1_k127_2024607_47 Polysaccharide biosynthesis protein - - - 0.000000000000000000000005404 117.0
HKD1_k127_2024607_48 VanZ like family - - - 0.000000000000000001402 91.0
HKD1_k127_2024607_49 DinB family - - - 0.000000000000008754 73.0
HKD1_k127_2024607_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.352e-253 786.0
HKD1_k127_2024607_52 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000004479 66.0
HKD1_k127_2024607_53 Cupin domain - - - 0.00000005233 59.0
HKD1_k127_2024607_55 Uncharacterized protein family UPF0016 - - - 0.00007066 46.0
HKD1_k127_2024607_56 Mycolic acid cyclopropane synthetase - - - 0.0008117 51.0
HKD1_k127_2024607_6 MatE - - - 3.186e-242 753.0
HKD1_k127_2024607_7 Protein of unknown function (DUF445) - - - 1.814e-230 718.0
HKD1_k127_2024607_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.574e-223 698.0
HKD1_k127_2024607_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 2.337e-200 632.0
HKD1_k127_2029068_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1404.0
HKD1_k127_2029068_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1374.0
HKD1_k127_2029068_10 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 572.0
HKD1_k127_2029068_11 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
HKD1_k127_2029068_12 Methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 513.0
HKD1_k127_2029068_13 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 488.0
HKD1_k127_2029068_14 pathogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 462.0
HKD1_k127_2029068_15 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 438.0
HKD1_k127_2029068_16 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 357.0
HKD1_k127_2029068_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001525 258.0
HKD1_k127_2029068_18 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001556 256.0
HKD1_k127_2029068_19 protein containing double-stranded beta helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000228 240.0
HKD1_k127_2029068_2 ABC-type Fe3 transport system permease component K02011 - - 4.683e-287 890.0
HKD1_k127_2029068_20 Sel1-like repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
HKD1_k127_2029068_21 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000001846 216.0
HKD1_k127_2029068_22 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
HKD1_k127_2029068_24 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000000000000005473 168.0
HKD1_k127_2029068_26 - - - - 0.00000000000000000000000001023 116.0
HKD1_k127_2029068_27 - - - - 0.0000000000000000000000164 111.0
HKD1_k127_2029068_28 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000001603 79.0
HKD1_k127_2029068_3 Surface antigen K07278 - - 5.887e-275 859.0
HKD1_k127_2029068_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.126e-226 714.0
HKD1_k127_2029068_5 Adenylate and Guanylate cyclase catalytic domain - - - 8.418e-221 724.0
HKD1_k127_2029068_6 Amidohydrolase - - - 4.745e-207 650.0
HKD1_k127_2029068_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 5.991e-198 622.0
HKD1_k127_2029068_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 582.0
HKD1_k127_2029068_9 ABC-type Fe3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 578.0
HKD1_k127_2051344_0 Class-II DAHP synthetase family - - - 2.757e-289 892.0
HKD1_k127_2051344_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 1.834e-287 888.0
HKD1_k127_2051344_10 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 599.0
HKD1_k127_2051344_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 539.0
HKD1_k127_2051344_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 535.0
HKD1_k127_2051344_13 Ca2 -binding protein (EF-Hand superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 475.0
HKD1_k127_2051344_14 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 428.0
HKD1_k127_2051344_15 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 414.0
HKD1_k127_2051344_16 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 389.0
HKD1_k127_2051344_17 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 351.0
HKD1_k127_2051344_18 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 358.0
HKD1_k127_2051344_19 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 308.0
HKD1_k127_2051344_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 7.68e-263 815.0
HKD1_k127_2051344_20 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000006406 213.0
HKD1_k127_2051344_22 EF-hand domain pair - - - 0.00000000000000000000000000000000000000000000000000000001647 201.0
HKD1_k127_2051344_24 Cytochrome c K08738 - - 0.0000000000000000000000000000000313 139.0
HKD1_k127_2051344_25 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000004816 79.0
HKD1_k127_2051344_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 2.447e-234 726.0
HKD1_k127_2051344_4 Receptor family ligand binding region - - - 2.516e-226 706.0
HKD1_k127_2051344_5 5-aminolevulinic acid synthase K00643 - 2.3.1.37 2.947e-224 714.0
HKD1_k127_2051344_6 Phosphate acyltransferases - - - 4.156e-224 736.0
HKD1_k127_2051344_7 Receptor family ligand binding region - - - 8.128e-222 692.0
HKD1_k127_2051344_8 Receptor family ligand binding region - - - 2.271e-220 688.0
HKD1_k127_2051344_9 Receptor family ligand binding region - - - 4.061e-201 634.0
HKD1_k127_206795_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.083e-250 788.0
HKD1_k127_206795_1 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 521.0
HKD1_k127_207952_0 Putative bacterial virulence factor - - - 0.0 1175.0
HKD1_k127_207952_1 Belongs to the heme-copper respiratory oxidase family - - - 0.0 1125.0
HKD1_k127_207952_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.256e-238 739.0
HKD1_k127_207952_3 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 444.0
HKD1_k127_207952_4 COX Aromatic Rich Motif K02297 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
HKD1_k127_207952_5 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
HKD1_k127_207952_6 Cytochrome c oxidase subunit III K02299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 303.0
HKD1_k127_207952_8 transposase activity - - - 0.00000000000000000000000000000006743 143.0
HKD1_k127_207952_9 Prokaryotic Cytochrome C oxidase subunit IV K02300 - - 0.0000000000000000000000000000128 130.0
HKD1_k127_208355_0 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0 1079.0
HKD1_k127_208355_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0 1025.0
HKD1_k127_208355_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 371.0
HKD1_k127_208355_11 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 361.0
HKD1_k127_208355_12 Glutathione S-transferase, C-terminal domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 357.0
HKD1_k127_208355_14 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
HKD1_k127_208355_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004819 270.0
HKD1_k127_208355_17 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000001567 179.0
HKD1_k127_208355_19 HWE histidine kinase - - - 0.00000000000000000000000000000001653 136.0
HKD1_k127_208355_2 Acyl-CoA dehydrogenase, middle domain - - - 1.022e-259 807.0
HKD1_k127_208355_20 - - - - 0.00000000000000000000000000001415 123.0
HKD1_k127_208355_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 4.679e-207 662.0
HKD1_k127_208355_5 protein conserved in bacteria K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 537.0
HKD1_k127_208355_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 494.0
HKD1_k127_208355_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 497.0
HKD1_k127_208355_8 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 439.0
HKD1_k127_208355_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 442.0
HKD1_k127_2085565_0 Glycosyl hydrolases family 25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 373.0
HKD1_k127_2085565_1 COG1994 Zn-dependent proteases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 314.0
HKD1_k127_2085565_2 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 315.0
HKD1_k127_2085565_3 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006832 264.0
HKD1_k127_2085565_4 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
HKD1_k127_2085565_5 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000000000000000000000000000000000522 229.0
HKD1_k127_2085565_7 Domain of unknown function (DUF4437) - - - 0.00000000000000000000000001089 115.0
HKD1_k127_2085565_8 - - - - 0.00000000000000000000000002184 117.0
HKD1_k127_2085565_9 - - - - 0.000000000000000004167 91.0
HKD1_k127_2114287_0 Protein of unknown function (DUF1298) - - - 6.062e-215 682.0
HKD1_k127_2114287_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001298 174.0
HKD1_k127_2114287_2 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000000000006421 143.0
HKD1_k127_2114287_3 acyl-coA-binding protein - - - 0.00000000000000000000000000000000000152 139.0
HKD1_k127_2114458_0 ATPases associated with a variety of cellular activities K06147 - - 6.237e-282 879.0
HKD1_k127_2114458_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 569.0
HKD1_k127_2114458_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 524.0
HKD1_k127_2114458_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 422.0
HKD1_k127_2127445_0 Adenylate cyclase K01768 - 4.6.1.1 2.755e-305 949.0
HKD1_k127_2127445_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 1.277e-212 670.0
HKD1_k127_2127445_2 Belongs to the amidase family K01426 - 3.5.1.4 2.77e-210 662.0
HKD1_k127_2127445_3 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 457.0
HKD1_k127_2127445_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001595 259.0
HKD1_k127_2127445_5 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
HKD1_k127_2127445_6 Cold shock K03704 - - 0.00000000000000000000000000000000002932 134.0
HKD1_k127_2127445_7 YXWGXW repeat (2 copies) - - - 0.000000000000000000000008283 104.0
HKD1_k127_2139681_0 Belongs to the ABC transporter superfamily K13896 - - 2.393e-296 926.0
HKD1_k127_2139681_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 1.052e-221 696.0
HKD1_k127_2139681_10 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 316.0
HKD1_k127_2139681_11 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001377 257.0
HKD1_k127_2139681_12 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000001678 237.0
HKD1_k127_2139681_13 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000002851 228.0
HKD1_k127_2139681_14 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000002 184.0
HKD1_k127_2139681_15 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000001803 162.0
HKD1_k127_2139681_16 DDE superfamily endonuclease - - - 0.000000000000000000000000000001105 121.0
HKD1_k127_2139681_17 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000005758 77.0
HKD1_k127_2139681_2 CoA-transferase family III - - - 6.299e-210 656.0
HKD1_k127_2139681_3 transport system, permease component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 583.0
HKD1_k127_2139681_4 transport system, permease component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 576.0
HKD1_k127_2139681_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 577.0
HKD1_k127_2139681_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 402.0
HKD1_k127_2139681_7 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 379.0
HKD1_k127_2139681_8 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 327.0
HKD1_k127_2139681_9 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 318.0
HKD1_k127_2160770_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1316.0
HKD1_k127_2160770_1 Periplasmic binding protein domain K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 479.0
HKD1_k127_2160770_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 397.0
HKD1_k127_2160770_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
HKD1_k127_2160770_4 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 304.0
HKD1_k127_2160770_5 Hydrogenase urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000006521 250.0
HKD1_k127_2160770_6 Protein of unknown function (DUF3995) - - - 0.00000000000000000000000000000000000000000000000000000000002558 219.0
HKD1_k127_2162207_0 PFAM ABC transporter K02471 - - 6.057e-205 656.0
HKD1_k127_2162207_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 484.0
HKD1_k127_2162207_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000001059 117.0
HKD1_k127_2162207_11 Fatty acid hydroxylase superfamily - - - 0.000000000000004649 75.0
HKD1_k127_2162207_12 PFAM Methyltransferase type 11 - - - 0.0000000002727 63.0
HKD1_k127_2162207_2 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 462.0
HKD1_k127_2162207_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 399.0
HKD1_k127_2162207_4 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 330.0
HKD1_k127_2162207_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 307.0
HKD1_k127_2162207_6 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 303.0
HKD1_k127_2162207_7 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000000000000002586 188.0
HKD1_k127_2162207_8 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000007569 123.0
HKD1_k127_2162207_9 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000002994 119.0
HKD1_k127_2179417_0 Sulfatase - - - 8.783e-292 900.0
HKD1_k127_2179417_1 Amidase K02433 - 6.3.5.6,6.3.5.7 1.335e-235 735.0
HKD1_k127_2179417_10 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000000000000000000001641 201.0
HKD1_k127_2179417_11 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000005192 198.0
HKD1_k127_2179417_12 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000003523 168.0
HKD1_k127_2179417_13 methyltransferase - - - 0.0000000000000000000000000000000000000000000005846 184.0
HKD1_k127_2179417_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000007894 156.0
HKD1_k127_2179417_15 CrcB-like protein, Camphor Resistance (CrcB) - - - 0.000000000000000000000000000002619 125.0
HKD1_k127_2179417_16 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000006621 115.0
HKD1_k127_2179417_2 FMN-dependent dehydrogenase K00104 - 1.1.3.15 1.993e-214 668.0
HKD1_k127_2179417_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 9.552e-200 627.0
HKD1_k127_2179417_4 Receptor family ligand binding region - - - 6.307e-194 611.0
HKD1_k127_2179417_5 Allophanate hydrolase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 586.0
HKD1_k127_2179417_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 469.0
HKD1_k127_2179417_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 331.0
HKD1_k127_2179417_9 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
HKD1_k127_2203759_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1744.0
HKD1_k127_2203759_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1668.0
HKD1_k127_2203759_10 cell division K05803 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 445.0
HKD1_k127_2203759_11 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 428.0
HKD1_k127_2203759_12 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 418.0
HKD1_k127_2203759_13 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 392.0
HKD1_k127_2203759_14 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 386.0
HKD1_k127_2203759_15 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
HKD1_k127_2203759_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1538.0
HKD1_k127_2203759_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1257.0
HKD1_k127_2203759_4 Amidase K02433 - 6.3.5.6,6.3.5.7 1.611e-236 737.0
HKD1_k127_2203759_5 serine-type peptidase activity - - - 4.67e-213 670.0
HKD1_k127_2203759_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 1.393e-197 623.0
HKD1_k127_2203759_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 581.0
HKD1_k127_2203759_8 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 623.0
HKD1_k127_2203759_9 Alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 478.0
HKD1_k127_2213269_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1131.0
HKD1_k127_2213269_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.178e-277 859.0
HKD1_k127_2213269_10 transcriptional regulator K05818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 302.0
HKD1_k127_2213269_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005526 275.0
HKD1_k127_2213269_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009013 249.0
HKD1_k127_2213269_2 Belongs to the ABC transporter superfamily - - - 1.472e-199 625.0
HKD1_k127_2213269_3 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 570.0
HKD1_k127_2213269_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 549.0
HKD1_k127_2213269_5 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 544.0
HKD1_k127_2213269_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 522.0
HKD1_k127_2213269_7 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 429.0
HKD1_k127_2213269_8 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HKD1_k127_2213269_9 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 319.0
HKD1_k127_2237086_0 Transport of potassium into the cell - - - 0.0 1064.0
HKD1_k127_2237086_1 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 1.007e-286 901.0
HKD1_k127_2237086_10 CHRD domain - - - 0.00000000000000000000000000000000000000002797 156.0
HKD1_k127_2237086_12 Protein of unknown function (DUF3592) - - - 0.0000000000000000000000000000000004503 151.0
HKD1_k127_2237086_13 - - - - 0.0000000000000000000000000001748 126.0
HKD1_k127_2237086_14 Ketosteroid isomerase-related protein - - - 0.0000000000000000000003295 102.0
HKD1_k127_2237086_2 cytochrome P-450 - - - 5.069e-219 685.0
HKD1_k127_2237086_3 Protein of unknown function (DUF917) K09703 - - 8.835e-203 641.0
HKD1_k127_2237086_4 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 402.0
HKD1_k127_2237086_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 400.0
HKD1_k127_2237086_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 385.0
HKD1_k127_2237086_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 331.0
HKD1_k127_2237086_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003955 241.0
HKD1_k127_2237086_9 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000001087 155.0
HKD1_k127_2264356_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 5.716e-249 781.0
HKD1_k127_2264356_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 1.459e-225 710.0
HKD1_k127_2264356_2 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 440.0
HKD1_k127_2264356_3 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 316.0
HKD1_k127_2264356_4 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
HKD1_k127_2264356_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000008253 172.0
HKD1_k127_2309566_0 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 1.721e-295 915.0
HKD1_k127_2309566_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 1.109e-293 904.0
HKD1_k127_2309566_2 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.495e-222 692.0
HKD1_k127_2309566_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 462.0
HKD1_k127_2309566_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 307.0
HKD1_k127_2309566_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001727 278.0
HKD1_k127_2309566_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
HKD1_k127_2309566_7 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.0000000000000000000000000000000000000000000009965 176.0
HKD1_k127_2309566_8 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000002627 111.0
HKD1_k127_2309566_9 Dodecin K09165 - - 0.00000000000000000000001163 103.0
HKD1_k127_2316253_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02055 - - 3.594e-199 623.0
HKD1_k127_2316253_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 557.0
HKD1_k127_2316253_2 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 519.0
HKD1_k127_2316253_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 463.0
HKD1_k127_2316253_4 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 344.0
HKD1_k127_2316253_5 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 338.0
HKD1_k127_2316253_6 AroM protein K14591 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
HKD1_k127_2316253_7 COG1176 ABC-type spermidine putrescine transport system permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001169 246.0
HKD1_k127_2318308_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1035.0
HKD1_k127_2318308_1 FMN_bind K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 514.0
HKD1_k127_2318308_2 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000000000000000000000000000000000000002894 186.0
HKD1_k127_231936_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 6.191e-237 736.0
HKD1_k127_231936_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.81e-219 683.0
HKD1_k127_231936_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 591.0
HKD1_k127_231936_3 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 380.0
HKD1_k127_231936_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000177 227.0
HKD1_k127_2342929_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1380.0
HKD1_k127_2342929_1 Patatin-like phospholipase K07001 - - 0.0 1030.0
HKD1_k127_2342929_10 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 477.0
HKD1_k127_2342929_11 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 377.0
HKD1_k127_2342929_12 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 318.0
HKD1_k127_2342929_13 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 312.0
HKD1_k127_2342929_14 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006032 275.0
HKD1_k127_2342929_15 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008875 265.0
HKD1_k127_2342929_16 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001377 279.0
HKD1_k127_2342929_17 Transcriptional regulatory protein, C terminal K14981 - - 0.000000000000000000000000000000000000000000000000000000000000000000007857 242.0
HKD1_k127_2342929_18 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000000001041 200.0
HKD1_k127_2342929_19 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000000000002758 198.0
HKD1_k127_2342929_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 9.652e-300 921.0
HKD1_k127_2342929_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000003096 197.0
HKD1_k127_2342929_21 Ring hydroxylating alpha subunit (catalytic domain) K16319,K18074 - 1.14.12.1,1.14.12.15 0.000000000000000000000000000000000000000000000000000004731 192.0
HKD1_k127_2342929_22 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000135 203.0
HKD1_k127_2342929_23 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.000000000000000000000000000000000000000000001226 171.0
HKD1_k127_2342929_24 transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000000000001831 168.0
HKD1_k127_2342929_25 Cupin domain K11312 - - 0.00000000000000000000000000000000000000001057 156.0
HKD1_k127_2342929_26 Protein of unknown function (DUF2000) - - - 0.0000000000000000000000000000000002291 138.0
HKD1_k127_2342929_27 Major Facilitator Superfamily - - - 0.00000001769 67.0
HKD1_k127_2342929_28 Protein of unknown function (DUF2000) - - - 0.000003265 58.0
HKD1_k127_2342929_29 SnoaL-like polyketide cyclase - - - 0.0003006 46.0
HKD1_k127_2342929_3 Flavoprotein involved in K transport - - - 1.658e-281 872.0
HKD1_k127_2342929_30 Protein of unknown function (DUF2000) - - - 0.0008714 46.0
HKD1_k127_2342929_4 Amidase - - - 1.753e-273 847.0
HKD1_k127_2342929_5 Thiolase, C-terminal domain - - - 4.408e-258 797.0
HKD1_k127_2342929_6 Protein of unknown function (DUF2817) - - - 8.479e-209 652.0
HKD1_k127_2342929_7 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 607.0
HKD1_k127_2342929_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 528.0
HKD1_k127_2342929_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 529.0
HKD1_k127_2366114_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1984.0
HKD1_k127_2366114_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1050.0
HKD1_k127_2366114_10 Intracellular septation protein A - - - 0.0000000000000000000000000000000000000000000000000003992 188.0
HKD1_k127_2366114_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000004545 185.0
HKD1_k127_2366114_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000008977 88.0
HKD1_k127_2366114_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00009016 44.0
HKD1_k127_2366114_2 Belongs to the CarA family K01956 - 6.3.5.5 1.004e-246 764.0
HKD1_k127_2366114_3 CoA-transferase family III - - - 1.612e-214 686.0
HKD1_k127_2366114_4 acyl-CoA dehydrogenase - - - 1.334e-210 655.0
HKD1_k127_2366114_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
HKD1_k127_2366114_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
HKD1_k127_2366114_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 477.0
HKD1_k127_2366114_8 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
HKD1_k127_2366114_9 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000003011 235.0
HKD1_k127_2369524_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.97e-251 779.0
HKD1_k127_2369524_1 glutamine synthetase K01915 - 6.3.1.2 2.112e-242 750.0
HKD1_k127_2369524_2 Aspartate tyrosine aromatic aminotransferase - - - 2.367e-233 724.0
HKD1_k127_2369524_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 7.362e-198 629.0
HKD1_k127_2369524_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 406.0
HKD1_k127_2369524_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 302.0
HKD1_k127_2369524_6 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 310.0
HKD1_k127_2369524_7 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
HKD1_k127_2369524_8 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000003732 241.0
HKD1_k127_2369524_9 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
HKD1_k127_239374_0 Binding-protein-dependent transport system inner membrane component K02050 - - 2.195e-296 917.0
HKD1_k127_239374_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 1.171e-241 770.0
HKD1_k127_239374_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000002219 257.0
HKD1_k127_239374_11 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002837 279.0
HKD1_k127_239374_12 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006033 275.0
HKD1_k127_239374_13 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001675 246.0
HKD1_k127_239374_14 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
HKD1_k127_239374_15 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000001047 153.0
HKD1_k127_239374_16 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000002256 137.0
HKD1_k127_239374_17 AntiSigma factor - - - 0.00000000000000000000001233 110.0
HKD1_k127_239374_18 Plasmid stabilization system - - - 0.000000000000000000003429 98.0
HKD1_k127_239374_19 - - - - 0.000000000000000001146 91.0
HKD1_k127_239374_2 C-terminal AAA-associated domain K02049 - - 1.73e-240 747.0
HKD1_k127_239374_20 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000002671 77.0
HKD1_k127_239374_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 8.744e-239 745.0
HKD1_k127_239374_4 HemY protein N-terminus K02498 - - 3.824e-237 739.0
HKD1_k127_239374_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 9.256e-207 644.0
HKD1_k127_239374_6 40-residue yvtn family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 596.0
HKD1_k127_239374_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 564.0
HKD1_k127_239374_8 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 579.0
HKD1_k127_239374_9 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001117 284.0
HKD1_k127_2421711_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 587.0
HKD1_k127_2421711_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 494.0
HKD1_k127_2421711_2 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 398.0
HKD1_k127_2421711_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
HKD1_k127_2421711_4 Protein of unknown function (DUF3987) - - - 0.000000000000000000000000000000000000000000000000001765 200.0
HKD1_k127_2421711_6 Asp/Glu/Hydantoin racemase - - - 0.000000000000000000000346 95.0
HKD1_k127_2430952_0 L-seryl-tRNA selenium transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 595.0
HKD1_k127_2430952_1 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 405.0
HKD1_k127_2430952_2 Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret K03383 - 3.5.2.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 392.0
HKD1_k127_2430952_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000002257 181.0
HKD1_k127_2431198_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1685.0
HKD1_k127_2431198_1 Hydantoinase/oxoprolinase - - - 0.0 1174.0
HKD1_k127_2431198_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 1.869e-247 769.0
HKD1_k127_2431198_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 474.0
HKD1_k127_2431198_4 Domain of unknown function DUF108 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 444.0
HKD1_k127_2431198_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 434.0
HKD1_k127_2431198_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
HKD1_k127_2431198_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000006944 148.0
HKD1_k127_2446724_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.576e-226 702.0
HKD1_k127_2446724_1 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 424.0
HKD1_k127_2446724_2 Exopolysaccharide synthesis, ExoD - - - 0.000000000000006068 75.0
HKD1_k127_2461909_0 Hydantoinase/oxoprolinase - - - 0.0 1185.0
HKD1_k127_2461909_1 Hydantoinase B/oxoprolinase - - - 0.0 1074.0
HKD1_k127_2461909_10 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 468.0
HKD1_k127_2461909_11 Thiamine biosynthesis K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 447.0
HKD1_k127_2461909_12 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 447.0
HKD1_k127_2461909_13 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 421.0
HKD1_k127_2461909_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 433.0
HKD1_k127_2461909_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 382.0
HKD1_k127_2461909_16 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 372.0
HKD1_k127_2461909_17 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 316.0
HKD1_k127_2461909_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 311.0
HKD1_k127_2461909_19 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 277.0
HKD1_k127_2461909_2 Histidine kinase K07638 - 2.7.13.3 1.749e-252 798.0
HKD1_k127_2461909_20 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 274.0
HKD1_k127_2461909_21 Phasin protein - - - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD1_k127_2461909_22 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000005236 196.0
HKD1_k127_2461909_23 Putative tRNA binding domain K06878 - - 0.0000000000000000000000000000000000000000000000000000006385 196.0
HKD1_k127_2461909_24 long-chain fatty acid transporting porin activity K09806 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000005457 149.0
HKD1_k127_2461909_25 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000000000000015 146.0
HKD1_k127_2461909_26 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000002553 99.0
HKD1_k127_2461909_27 Protein of unknown function (DUF2630) - - - 0.000000000000000007943 86.0
HKD1_k127_2461909_3 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 2.985e-225 703.0
HKD1_k127_2461909_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.111e-210 655.0
HKD1_k127_2461909_5 Amino-transferase class IV K00826 - 2.6.1.42 2.297e-209 653.0
HKD1_k127_2461909_6 NMT1-like family K15576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 591.0
HKD1_k127_2461909_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 552.0
HKD1_k127_2461909_8 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 541.0
HKD1_k127_2461909_9 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 494.0
HKD1_k127_2469447_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0 1079.0
HKD1_k127_2469447_1 Aminotransferase K14261 - - 2.882e-254 799.0
HKD1_k127_2469447_10 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 359.0
HKD1_k127_2469447_11 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 348.0
HKD1_k127_2469447_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 296.0
HKD1_k127_2469447_13 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 287.0
HKD1_k127_2469447_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001011 265.0
HKD1_k127_2469447_15 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004155 264.0
HKD1_k127_2469447_16 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002481 270.0
HKD1_k127_2469447_17 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
HKD1_k127_2469447_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000007375 217.0
HKD1_k127_2469447_19 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000001518 196.0
HKD1_k127_2469447_2 homoserine dehydrogenase K00003 - 1.1.1.3 2.787e-232 724.0
HKD1_k127_2469447_20 - - - - 0.000000000000000000000000000000000000000001772 167.0
HKD1_k127_2469447_21 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.0000000000000000000000000000000000000007348 156.0
HKD1_k127_2469447_23 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000004108 104.0
HKD1_k127_2469447_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 469.0
HKD1_k127_2469447_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 455.0
HKD1_k127_2469447_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 430.0
HKD1_k127_2469447_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 427.0
HKD1_k127_2469447_7 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 399.0
HKD1_k127_2469447_8 nitrogen compound transport K00759,K02033 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 385.0
HKD1_k127_2469447_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
HKD1_k127_250631_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.036e-300 952.0
HKD1_k127_250631_1 TIGRFAM FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family K20938 - 1.14.14.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 533.0
HKD1_k127_250631_10 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000000000000000000002307 198.0
HKD1_k127_250631_11 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000001196 130.0
HKD1_k127_250631_2 of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 512.0
HKD1_k127_250631_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 324.0
HKD1_k127_250631_4 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 324.0
HKD1_k127_250631_5 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 321.0
HKD1_k127_250631_6 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002659 279.0
HKD1_k127_250631_7 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002156 277.0
HKD1_k127_250631_8 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003129 249.0
HKD1_k127_250631_9 - - - - 0.0000000000000000000000000000000000000000000000000000000008464 216.0
HKD1_k127_251941_0 ABC transporter substrate-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 530.0
HKD1_k127_251941_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 426.0
HKD1_k127_251941_10 - - - - 0.000000000000000000000000000000000000000000000007809 184.0
HKD1_k127_251941_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000001138 162.0
HKD1_k127_251941_12 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000002586 153.0
HKD1_k127_251941_13 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000005555 156.0
HKD1_k127_251941_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000006269 65.0
HKD1_k127_251941_2 In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 368.0
HKD1_k127_251941_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 363.0
HKD1_k127_251941_4 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.99.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 350.0
HKD1_k127_251941_5 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 338.0
HKD1_k127_251941_6 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 322.0
HKD1_k127_251941_7 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001674 245.0
HKD1_k127_251941_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000001407 235.0
HKD1_k127_251941_9 May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation K09021 - - 0.00000000000000000000000000000000000000000000000000000000001036 208.0
HKD1_k127_2530030_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.494e-318 982.0
HKD1_k127_2530030_1 homoserine dehydrogenase - - - 3.559e-282 869.0
HKD1_k127_2530030_10 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 359.0
HKD1_k127_2530030_11 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 366.0
HKD1_k127_2530030_12 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 365.0
HKD1_k127_2530030_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 316.0
HKD1_k127_2530030_14 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 314.0
HKD1_k127_2530030_15 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 334.0
HKD1_k127_2530030_16 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 316.0
HKD1_k127_2530030_17 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
HKD1_k127_2530030_18 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 282.0
HKD1_k127_2530030_19 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001097 276.0
HKD1_k127_2530030_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 579.0
HKD1_k127_2530030_20 Globin - - - 0.0000000000000000000000000000000000000000000000000000001092 199.0
HKD1_k127_2530030_21 - - - - 0.00000000000000000000000000000000000000034 159.0
HKD1_k127_2530030_22 PFAM NUDIX hydrolase K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.6.1.67 0.0000000000000000000000000000000000000009194 151.0
HKD1_k127_2530030_23 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000002091 145.0
HKD1_k127_2530030_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000000003774 133.0
HKD1_k127_2530030_25 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000002392 84.0
HKD1_k127_2530030_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 526.0
HKD1_k127_2530030_4 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 524.0
HKD1_k127_2530030_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 435.0
HKD1_k127_2530030_6 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 413.0
HKD1_k127_2530030_7 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 407.0
HKD1_k127_2530030_8 Ca2 -binding protein (EF-Hand superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 405.0
HKD1_k127_2530030_9 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 404.0
HKD1_k127_2599884_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 524.0
HKD1_k127_2599884_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 522.0
HKD1_k127_2599884_12 Periplasmic Protein K09914 - - 0.00000000000000000000000000000961 123.0
HKD1_k127_2599884_13 SmpA / OmlA family - - - 0.00000000000000000000001189 112.0
HKD1_k127_2599884_15 Ami_2 - - - 0.0000000001776 72.0
HKD1_k127_2599884_16 - - - - 0.00001567 53.0
HKD1_k127_2599884_2 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 365.0
HKD1_k127_2599884_3 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 351.0
HKD1_k127_2599884_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 360.0
HKD1_k127_2599884_5 PFAM NnrUfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003573 279.0
HKD1_k127_2599884_6 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 290.0
HKD1_k127_2599884_7 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004735 277.0
HKD1_k127_2599884_8 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
HKD1_k127_2599884_9 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000004775 223.0
HKD1_k127_2607638_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2454.0
HKD1_k127_2607638_1 HELICc2 K03722 - 3.6.4.12 0.0 1639.0
HKD1_k127_2607638_10 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 435.0
HKD1_k127_2607638_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 422.0
HKD1_k127_2607638_12 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 411.0
HKD1_k127_2607638_13 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 395.0
HKD1_k127_2607638_14 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HKD1_k127_2607638_15 Ureidoglycolate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 374.0
HKD1_k127_2607638_16 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 368.0
HKD1_k127_2607638_17 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 351.0
HKD1_k127_2607638_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 327.0
HKD1_k127_2607638_19 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
HKD1_k127_2607638_2 Major Facilitator Superfamily K02575 - - 0.0 1633.0
HKD1_k127_2607638_20 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004247 282.0
HKD1_k127_2607638_21 B-1 B cell differentiation K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 277.0
HKD1_k127_2607638_22 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002781 264.0
HKD1_k127_2607638_23 Protein of unknown function (DUF2478) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005943 260.0
HKD1_k127_2607638_24 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000008315 214.0
HKD1_k127_2607638_25 - - - - 0.0000000000000000000000000000000000000000000000004141 179.0
HKD1_k127_2607638_26 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002899 140.0
HKD1_k127_2607638_27 - - - - 0.0000000000000000000000000000001047 126.0
HKD1_k127_2607638_28 Belongs to the ompA family - - - 0.00000000000000000000000000000118 130.0
HKD1_k127_2607638_29 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000006754 109.0
HKD1_k127_2607638_3 Nitrate reductase beta subunit K00371 - 1.7.5.1 0.0 1032.0
HKD1_k127_2607638_31 - - - - 0.0000000000000000000003434 105.0
HKD1_k127_2607638_32 Flavodoxin-like fold K00355 - 1.6.5.2 0.00006521 55.0
HKD1_k127_2607638_4 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 8.62e-317 975.0
HKD1_k127_2607638_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 9.091e-228 727.0
HKD1_k127_2607638_6 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 526.0
HKD1_k127_2607638_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 526.0
HKD1_k127_2607638_8 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
HKD1_k127_2607638_9 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 441.0
HKD1_k127_261905_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 437.0
HKD1_k127_261905_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 367.0
HKD1_k127_261905_2 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 312.0
HKD1_k127_261905_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
HKD1_k127_261905_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
HKD1_k127_261905_5 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000003443 230.0
HKD1_k127_261905_6 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000000000000000006167 208.0
HKD1_k127_261905_7 decarboxylase - - - 0.0000000000001004 77.0
HKD1_k127_2630795_0 AcrB/AcrD/AcrF family - - - 0.0 1741.0
HKD1_k127_2630795_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1356.0
HKD1_k127_2630795_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 578.0
HKD1_k127_2630795_11 HlyD membrane-fusion protein of T1SS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 557.0
HKD1_k127_2630795_12 FAD binding domain K05898,K13796 - 1.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 559.0
HKD1_k127_2630795_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 556.0
HKD1_k127_2630795_14 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 508.0
HKD1_k127_2630795_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 495.0
HKD1_k127_2630795_16 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 460.0
HKD1_k127_2630795_17 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 455.0
HKD1_k127_2630795_18 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 424.0
HKD1_k127_2630795_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 403.0
HKD1_k127_2630795_2 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1179.0
HKD1_k127_2630795_20 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
HKD1_k127_2630795_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 387.0
HKD1_k127_2630795_22 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 323.0
HKD1_k127_2630795_23 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
HKD1_k127_2630795_24 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
HKD1_k127_2630795_25 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 291.0
HKD1_k127_2630795_26 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000845 297.0
HKD1_k127_2630795_27 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001838 274.0
HKD1_k127_2630795_28 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002531 271.0
HKD1_k127_2630795_29 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 251.0
HKD1_k127_2630795_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0 1034.0
HKD1_k127_2630795_30 Protein of unknown function (DUF3225) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004505 237.0
HKD1_k127_2630795_31 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000002395 218.0
HKD1_k127_2630795_32 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000007235 220.0
HKD1_k127_2630795_33 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
HKD1_k127_2630795_34 ABC transporter K02035 - - 0.000000000000000000000000000000000000000000000000000000000007941 223.0
HKD1_k127_2630795_35 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000002081 166.0
HKD1_k127_2630795_36 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000004614 154.0
HKD1_k127_2630795_37 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000000002463 147.0
HKD1_k127_2630795_38 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000005938 144.0
HKD1_k127_2630795_4 Major Facilitator Superfamily - - - 3.304e-243 760.0
HKD1_k127_2630795_40 PFAM Glutathione S-transferase domain - - - 0.0000000000000000000000000000002084 131.0
HKD1_k127_2630795_5 carboxylic acid catabolic process - - - 1.063e-236 733.0
HKD1_k127_2630795_6 FAD dependent oxidoreductase - - - 1.741e-225 705.0
HKD1_k127_2630795_7 P-aminobenzoate N-oxygenase AurF - - - 6.635e-222 691.0
HKD1_k127_2630795_8 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 9.479e-215 670.0
HKD1_k127_2630795_9 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 6.192e-198 620.0
HKD1_k127_2633049_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.071e-320 994.0
HKD1_k127_2633049_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 299.0
HKD1_k127_2652458_0 COG1960 Acyl-CoA dehydrogenases - - - 2.771e-231 718.0
HKD1_k127_2652458_1 transport protein CorA K03284 - - 2.14e-204 643.0
HKD1_k127_2652458_10 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001672 270.0
HKD1_k127_2652458_11 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006607 243.0
HKD1_k127_2652458_12 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 239.0
HKD1_k127_2652458_13 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000008546 211.0
HKD1_k127_2652458_14 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000002953 180.0
HKD1_k127_2652458_2 Belongs to the ALAD family K01698 - 4.2.1.24 5.755e-198 619.0
HKD1_k127_2652458_3 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 601.0
HKD1_k127_2652458_4 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 487.0
HKD1_k127_2652458_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 485.0
HKD1_k127_2652458_6 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 455.0
HKD1_k127_2652458_7 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 376.0
HKD1_k127_2652458_8 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 328.0
HKD1_k127_2652458_9 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 292.0
HKD1_k127_2684031_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 1.14e-321 996.0
HKD1_k127_2684031_1 ABC-type Fe3 transport system permease component K02011 - - 1.227e-301 933.0
HKD1_k127_2684031_2 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 5.268e-280 885.0
HKD1_k127_2684031_3 Bacterial extracellular solute-binding protein K02012 - - 2.207e-198 622.0
HKD1_k127_2684031_4 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 577.0
HKD1_k127_2684031_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 337.0
HKD1_k127_2684031_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005803 285.0
HKD1_k127_2684031_7 Peptidase M15A K03791 - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
HKD1_k127_2684031_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000003032 173.0
HKD1_k127_2685904_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.068e-314 971.0
HKD1_k127_2685904_1 Heparinase II/III-like protein - - - 7.629e-287 890.0
HKD1_k127_2685904_10 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 410.0
HKD1_k127_2685904_11 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 327.0
HKD1_k127_2685904_12 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 261.0
HKD1_k127_2685904_13 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003435 259.0
HKD1_k127_2685904_14 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001758 251.0
HKD1_k127_2685904_15 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001541 239.0
HKD1_k127_2685904_16 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000005293 186.0
HKD1_k127_2685904_17 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000002581 170.0
HKD1_k127_2685904_18 Cupin domain - - - 0.00000000000000000000000000000000000000000002443 167.0
HKD1_k127_2685904_19 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000131 164.0
HKD1_k127_2685904_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.745e-277 859.0
HKD1_k127_2685904_22 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000000000006643 118.0
HKD1_k127_2685904_23 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000003918 126.0
HKD1_k127_2685904_24 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000000000393 115.0
HKD1_k127_2685904_25 ClpX C4-type zinc finger - - - 0.000000000000000000000004051 106.0
HKD1_k127_2685904_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.34e-264 822.0
HKD1_k127_2685904_4 FAD binding domain K20940 - 1.14.13.218 1.83e-237 737.0
HKD1_k127_2685904_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 3.418e-194 616.0
HKD1_k127_2685904_6 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 500.0
HKD1_k127_2685904_7 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 513.0
HKD1_k127_2685904_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 466.0
HKD1_k127_2685904_9 peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 459.0
HKD1_k127_2689039_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1601.0
HKD1_k127_2689039_1 Protein of unknown function - - - 0.0 1360.0
HKD1_k127_2689039_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000005717 130.0
HKD1_k127_2689039_12 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.00000000002217 74.0
HKD1_k127_2689039_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 6.289e-237 743.0
HKD1_k127_2689039_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.682e-236 738.0
HKD1_k127_2689039_4 FAD binding domain - - - 2.041e-213 672.0
HKD1_k127_2689039_5 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 500.0
HKD1_k127_2689039_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 452.0
HKD1_k127_2689039_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
HKD1_k127_2689039_8 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000005568 149.0
HKD1_k127_2689039_9 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000004588 152.0
HKD1_k127_2690810_0 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 0.0 1163.0
HKD1_k127_2690810_1 Mg2 and Co2 transporter CorB - - - 7.908e-229 716.0
HKD1_k127_2690810_10 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 338.0
HKD1_k127_2690810_11 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 293.0
HKD1_k127_2690810_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000016 308.0
HKD1_k127_2690810_13 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004243 274.0
HKD1_k127_2690810_14 Putative zinc- or iron-chelating domain K09160 - - 0.00000000000000000000000000000000000000000000000000000001137 205.0
HKD1_k127_2690810_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000000000000000008708 184.0
HKD1_k127_2690810_16 Belongs to the BolA IbaG family K05527,K22066 - - 0.000000000000000000000000000000000000000003779 156.0
HKD1_k127_2690810_17 GIY-YIG catalytic domain - - - 0.00000000000000004044 88.0
HKD1_k127_2690810_2 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 1.765e-210 657.0
HKD1_k127_2690810_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 1.864e-198 633.0
HKD1_k127_2690810_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 558.0
HKD1_k127_2690810_6 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 480.0
HKD1_k127_2690810_7 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 481.0
HKD1_k127_2690810_8 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 403.0
HKD1_k127_2690810_9 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 388.0
HKD1_k127_2727474_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0 1132.0
HKD1_k127_2727474_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1040.0
HKD1_k127_2727474_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 3.874e-281 869.0
HKD1_k127_2727474_3 histidine ammonia-lyase activity K01745 - 4.3.1.3 1.904e-254 792.0
HKD1_k127_2727474_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.526e-232 723.0
HKD1_k127_2727474_6 - - - - 0.000007881 58.0
HKD1_k127_2733187_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1210.0
HKD1_k127_2733187_1 TIGRFAM L-lactate transport K03303 - - 8.243e-277 861.0
HKD1_k127_2733187_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.578e-199 635.0
HKD1_k127_2733187_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 488.0
HKD1_k127_2733187_4 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 435.0
HKD1_k127_2733187_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 407.0
HKD1_k127_2733187_7 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000006252 184.0
HKD1_k127_2733187_8 - - - - 0.0000000001288 66.0
HKD1_k127_2733187_9 Protein of unknown function (DUF3175) - - - 0.0000000001514 64.0
HKD1_k127_2741603_0 ImcF-related N-terminal domain K11891 - - 0.0 1771.0
HKD1_k127_2741603_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 2.426e-297 919.0
HKD1_k127_2741603_10 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 552.0
HKD1_k127_2741603_11 conserved protein, contains FHA domain K11894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 557.0
HKD1_k127_2741603_12 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 547.0
HKD1_k127_2741603_13 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 471.0
HKD1_k127_2741603_14 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 455.0
HKD1_k127_2741603_15 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD1_k127_2741603_16 Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
HKD1_k127_2741603_17 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 427.0
HKD1_k127_2741603_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 373.0
HKD1_k127_2741603_19 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 379.0
HKD1_k127_2741603_2 peptidase U62, modulator of DNA gyrase K03568 - - 2.994e-278 860.0
HKD1_k127_2741603_20 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
HKD1_k127_2741603_21 GMP synthase (glutamine-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
HKD1_k127_2741603_22 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003918 260.0
HKD1_k127_2741603_23 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
HKD1_k127_2741603_24 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.0000000000000000000000000000000000000000000000000000000001696 205.0
HKD1_k127_2741603_25 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
HKD1_k127_2741603_26 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000008176 219.0
HKD1_k127_2741603_27 Type VI secretion K11906 - - 0.0000000000000000000000000000000000000000000001569 177.0
HKD1_k127_2741603_28 - - - - 0.000000000000000000000000000000000000000000001411 175.0
HKD1_k127_2741603_29 - - - - 0.0000000000000000000000000000000000000000000059 172.0
HKD1_k127_2741603_3 Protein conserved in bacteria K11893 - - 1.962e-266 831.0
HKD1_k127_2741603_30 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000002035 164.0
HKD1_k127_2741603_31 transcriptional regulator, ArsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000006005 143.0
HKD1_k127_2741603_32 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000449 117.0
HKD1_k127_2741603_35 - - - - 0.000000000000000181 81.0
HKD1_k127_2741603_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.878e-259 802.0
HKD1_k127_2741603_5 Autotransporter beta-domain - - - 2.94e-239 757.0
HKD1_k127_2741603_6 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 9.098e-232 720.0
HKD1_k127_2741603_7 Type VI secretion system protein DotU K11892 - - 7.838e-223 698.0
HKD1_k127_2741603_8 Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 607.0
HKD1_k127_2741603_9 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 569.0
HKD1_k127_275093_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 2182.0
HKD1_k127_275093_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00612 - - 0.0 1138.0
HKD1_k127_275093_10 Carboxyl transferase domain - - - 8.999e-234 734.0
HKD1_k127_275093_11 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 2.819e-214 670.0
HKD1_k127_275093_12 alpha/beta hydrolase fold K03821 - - 6.016e-209 657.0
HKD1_k127_275093_13 Belongs to the thiolase family K00626 - 2.3.1.9 4.993e-198 623.0
HKD1_k127_275093_14 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 591.0
HKD1_k127_275093_15 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 576.0
HKD1_k127_275093_16 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 557.0
HKD1_k127_275093_17 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 543.0
HKD1_k127_275093_18 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 509.0
HKD1_k127_275093_19 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 480.0
HKD1_k127_275093_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 3.976e-297 917.0
HKD1_k127_275093_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 468.0
HKD1_k127_275093_21 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 459.0
HKD1_k127_275093_22 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 443.0
HKD1_k127_275093_23 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 437.0
HKD1_k127_275093_24 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 433.0
HKD1_k127_275093_25 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 437.0
HKD1_k127_275093_26 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 437.0
HKD1_k127_275093_27 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 404.0
HKD1_k127_275093_28 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 407.0
HKD1_k127_275093_29 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 401.0
HKD1_k127_275093_3 Sodium/hydrogen exchanger family - - - 3.238e-291 909.0
HKD1_k127_275093_30 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 393.0
HKD1_k127_275093_31 COG3279 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 398.0
HKD1_k127_275093_32 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 381.0
HKD1_k127_275093_33 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 374.0
HKD1_k127_275093_34 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
HKD1_k127_275093_35 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 360.0
HKD1_k127_275093_36 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 357.0
HKD1_k127_275093_37 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
HKD1_k127_275093_38 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
HKD1_k127_275093_39 Belongs to the glycosyl hydrolase 18 family K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 370.0
HKD1_k127_275093_4 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 2.07e-272 863.0
HKD1_k127_275093_40 Universal stress protein UspA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
HKD1_k127_275093_41 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 329.0
HKD1_k127_275093_42 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 329.0
HKD1_k127_275093_43 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
HKD1_k127_275093_44 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 306.0
HKD1_k127_275093_45 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 291.0
HKD1_k127_275093_46 hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
HKD1_k127_275093_47 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 293.0
HKD1_k127_275093_48 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 292.0
HKD1_k127_275093_49 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
HKD1_k127_275093_5 Luciferase-like monooxygenase - - - 3.438e-260 806.0
HKD1_k127_275093_50 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006503 263.0
HKD1_k127_275093_51 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
HKD1_k127_275093_52 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005724 243.0
HKD1_k127_275093_53 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
HKD1_k127_275093_54 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000000000000000000000004013 245.0
HKD1_k127_275093_55 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000005445 251.0
HKD1_k127_275093_56 Domain of unknown function (DUF4864) - - - 0.00000000000000000000000000000000000000000000000000000000000000006949 225.0
HKD1_k127_275093_57 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001568 224.0
HKD1_k127_275093_58 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000001938 234.0
HKD1_k127_275093_59 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000000000000000001142 235.0
HKD1_k127_275093_6 Amidase - - - 6.851e-256 796.0
HKD1_k127_275093_60 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000001799 223.0
HKD1_k127_275093_61 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000001949 207.0
HKD1_k127_275093_62 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000002802 222.0
HKD1_k127_275093_63 PFAM FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002863 218.0
HKD1_k127_275093_64 VIT family - - - 0.000000000000000000000000000000000000000000000000000522 191.0
HKD1_k127_275093_65 NIPSNAP - - - 0.000000000000000000000000000000000000000000000001089 196.0
HKD1_k127_275093_66 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000002064 166.0
HKD1_k127_275093_67 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000004212 156.0
HKD1_k127_275093_68 Sodium Bile acid symporter family - - - 0.000000000000000000000000000000000000001394 170.0
HKD1_k127_275093_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.316e-255 805.0
HKD1_k127_275093_70 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.000000000000000000000000000005635 118.0
HKD1_k127_275093_72 Protein of unknown function (DUF1348) - - - 0.0000000000000000000000000001794 118.0
HKD1_k127_275093_73 - - - - 0.000000000000000000000000005466 117.0
HKD1_k127_275093_76 - - - - 0.000000000000000002687 93.0
HKD1_k127_275093_77 Fe-S protein K06938 - - 0.00000000000000007373 88.0
HKD1_k127_275093_79 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000004547 74.0
HKD1_k127_275093_8 Hydrolyzes N-terminal residues in D-amino acid- containing peptides K01266 - 3.4.11.19 7.379e-245 768.0
HKD1_k127_275093_80 - - - - 0.0000000002118 67.0
HKD1_k127_275093_82 Hydrolyzes N-terminal residues in D-amino acid- containing peptides K01266 - 3.4.11.19 0.00001995 57.0
HKD1_k127_275093_83 - - - - 0.00005778 55.0
HKD1_k127_275093_84 GDSL-like Lipase/Acylhydrolase family - - - 0.0001846 53.0
HKD1_k127_275093_9 PFAM peptidase S15 K06978 - - 1.127e-241 762.0
HKD1_k127_2771486_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 4.078e-312 982.0
HKD1_k127_2771486_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 6.478e-246 764.0
HKD1_k127_2771486_2 Glycine cleavage system T protein K00605 - 2.1.2.10 3.605e-208 655.0
HKD1_k127_2771486_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000006966 227.0
HKD1_k127_2771486_4 phosphatase - - - 0.000000000000000000000000000000000000006895 147.0
HKD1_k127_2771486_5 plasmid maintenance system antidote protein K21498 - - 0.000000000000000000002318 98.0
HKD1_k127_2778611_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1658.0
HKD1_k127_2778611_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1353.0
HKD1_k127_2778611_11 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 289.0
HKD1_k127_2778611_12 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002976 281.0
HKD1_k127_2778611_13 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002854 267.0
HKD1_k127_2778611_14 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 259.0
HKD1_k127_2778611_15 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000000000001104 163.0
HKD1_k127_2778611_16 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000001167 160.0
HKD1_k127_2778611_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 9.512e-243 756.0
HKD1_k127_2778611_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.653e-225 705.0
HKD1_k127_2778611_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.219e-201 633.0
HKD1_k127_2778611_5 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 541.0
HKD1_k127_2778611_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 476.0
HKD1_k127_2778611_7 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 461.0
HKD1_k127_2778611_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 430.0
HKD1_k127_2778611_9 sequence-specific DNA binding K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 373.0
HKD1_k127_2802575_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1210.0
HKD1_k127_2802575_1 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000000000000003777 169.0
HKD1_k127_2802575_2 Belongs to the frataxin family K19054 - 1.16.3.1 0.0000000000000000000000000000000000000000225 156.0
HKD1_k127_2802575_3 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000004235 93.0
HKD1_k127_2805127_0 Acyl-CoA dehydrogenase, middle domain - - - 9.84e-231 715.0
HKD1_k127_2805127_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
HKD1_k127_2897845_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 597.0
HKD1_k127_2897845_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 495.0
HKD1_k127_2897845_10 acid phosphatase activity - - - 0.000005822 60.0
HKD1_k127_2897845_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 436.0
HKD1_k127_2897845_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 321.0
HKD1_k127_2897845_4 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000117 315.0
HKD1_k127_2897845_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003203 286.0
HKD1_k127_2897845_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002967 285.0
HKD1_k127_2897845_7 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000004739 253.0
HKD1_k127_2897845_8 ABC transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000005448 232.0
HKD1_k127_2897845_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000002511 208.0
HKD1_k127_2973086_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0 1053.0
HKD1_k127_2973086_1 Belongs to the UbiD family K03182 - 4.1.1.98 1.766e-301 925.0
HKD1_k127_2973086_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 9.085e-213 670.0
HKD1_k127_2973086_11 Protein of unknown function (DUF3419) - - - 1.115e-206 649.0
HKD1_k127_2973086_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.984e-195 622.0
HKD1_k127_2973086_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 579.0
HKD1_k127_2973086_14 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 555.0
HKD1_k127_2973086_15 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 543.0
HKD1_k127_2973086_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 536.0
HKD1_k127_2973086_17 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 507.0
HKD1_k127_2973086_18 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 447.0
HKD1_k127_2973086_19 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 437.0
HKD1_k127_2973086_2 Zn-dependent proteases and their inactivated homologs K03592 - - 9.541e-248 771.0
HKD1_k127_2973086_20 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 383.0
HKD1_k127_2973086_21 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 373.0
HKD1_k127_2973086_22 Methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 292.0
HKD1_k127_2973086_23 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002131 292.0
HKD1_k127_2973086_24 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009952 287.0
HKD1_k127_2973086_25 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004648 277.0
HKD1_k127_2973086_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
HKD1_k127_2973086_27 Protein of unknown function (DUF2852) - - - 0.000000000000000000000000000000000000000000000000000000000000007163 218.0
HKD1_k127_2973086_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
HKD1_k127_2973086_29 PIN domain - - - 0.0000000000000000000000000009599 117.0
HKD1_k127_2973086_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.767e-246 768.0
HKD1_k127_2973086_30 - - - - 0.00000000000000000004347 92.0
HKD1_k127_2973086_32 positive regulation of growth - - - 0.00000000004445 66.0
HKD1_k127_2973086_4 ABC transporter transmembrane region K06147 - - 3.455e-240 756.0
HKD1_k127_2973086_5 L-carnitine dehydratase bile acid-inducible protein - - - 1.075e-239 743.0
HKD1_k127_2973086_6 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.061e-236 734.0
HKD1_k127_2973086_7 Belongs to the GARS family K01945 - 6.3.4.13 1.09e-228 713.0
HKD1_k127_2973086_8 Metallo-beta-lactamase superfamily - - - 1.215e-225 701.0
HKD1_k127_2973086_9 Lytic murein transglycosylase K08305 - - 5.422e-217 678.0
HKD1_k127_3043847_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 5.125e-318 981.0
HKD1_k127_3043847_1 Paraquat-inducible protein B K06192 - - 1.209e-253 793.0
HKD1_k127_3043847_2 paraquat-inducible protein A K03808 - - 2.012e-202 640.0
HKD1_k127_3043847_3 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 584.0
HKD1_k127_3043847_4 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 388.0
HKD1_k127_3043847_5 Protein conserved in bacteria K09857 - - 0.000000000000000000000000000000000000000000000000000000000000000005881 245.0
HKD1_k127_3061132_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 5.666e-266 822.0
HKD1_k127_3061132_1 metal-dependent hydrolase of the TIM-barrel fold - - - 5.449e-234 727.0
HKD1_k127_3061132_10 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
HKD1_k127_3061132_11 cation efflux K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 380.0
HKD1_k127_3061132_12 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 358.0
HKD1_k127_3061132_13 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HKD1_k127_3061132_14 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 325.0
HKD1_k127_3061132_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004689 265.0
HKD1_k127_3061132_16 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
HKD1_k127_3061132_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
HKD1_k127_3061132_18 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
HKD1_k127_3061132_19 TIR domain - - - 0.0000000000000000000000000000000000000000007483 181.0
HKD1_k127_3061132_2 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.339e-203 638.0
HKD1_k127_3061132_20 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000001451 143.0
HKD1_k127_3061132_21 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000008492 126.0
HKD1_k127_3061132_3 Retinal pigment epithelial membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 588.0
HKD1_k127_3061132_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 596.0
HKD1_k127_3061132_5 SMP-30/Gluconolaconase/LRE-like region K02352 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 552.0
HKD1_k127_3061132_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 498.0
HKD1_k127_3061132_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 413.0
HKD1_k127_3061132_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 396.0
HKD1_k127_3061132_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 400.0
HKD1_k127_3071437_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0 1011.0
HKD1_k127_3071437_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 9.405e-298 919.0
HKD1_k127_3071437_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
HKD1_k127_3071437_11 Tetratricopeptide repeat - - - 0.0000002247 53.0
HKD1_k127_3071437_2 Putative serine dehydratase domain - - - 6.759e-213 664.0
HKD1_k127_3071437_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 565.0
HKD1_k127_3071437_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 513.0
HKD1_k127_3071437_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 444.0
HKD1_k127_3071437_6 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 461.0
HKD1_k127_3071437_7 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 403.0
HKD1_k127_3071437_8 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 364.0
HKD1_k127_3071437_9 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 271.0
HKD1_k127_3074075_0 L-lactate permease K03303 - - 4.095e-235 734.0
HKD1_k127_3074075_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 516.0
HKD1_k127_3074075_2 Pfam:DUF4102 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HKD1_k127_3074075_3 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 365.0
HKD1_k127_3074075_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 336.0
HKD1_k127_3074075_5 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000003865 180.0
HKD1_k127_3085043_0 Amidase K02433 - 6.3.5.6,6.3.5.7 7.518e-281 887.0
HKD1_k127_3085043_1 repeat protein - - - 1.116e-268 833.0
HKD1_k127_3085043_11 - - - - 0.00000007287 61.0
HKD1_k127_3085043_2 Amidase K02433 - 6.3.5.6,6.3.5.7 2.379e-249 796.0
HKD1_k127_3085043_3 Methionine synthase K00549 - 2.1.1.14 4.947e-208 650.0
HKD1_k127_3085043_4 COG0457 FOG TPR repeat - - - 1.5e-204 642.0
HKD1_k127_3085043_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 376.0
HKD1_k127_3085043_6 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008296 261.0
HKD1_k127_3085043_7 - - - - 0.000000000000000000000000000000000000000000000000000000000003959 216.0
HKD1_k127_3085043_8 FecR protein - - - 0.000000000000000000000000000661 126.0
HKD1_k127_3085043_9 DNA-dependent DNA replication - - - 0.0000000000000003286 93.0
HKD1_k127_3101616_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1633.0
HKD1_k127_3101616_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1089.0
HKD1_k127_3101616_10 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 430.0
HKD1_k127_3101616_11 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 416.0
HKD1_k127_3101616_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 332.0
HKD1_k127_3101616_13 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 286.0
HKD1_k127_3101616_14 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009041 229.0
HKD1_k127_3101616_15 protein acetylation - - - 0.000000000000000000000000000000000000000000000000000000000002015 214.0
HKD1_k127_3101616_16 LTXXQ motif family protein - - - 0.000000000000000000000000000000000000000000000000000006578 196.0
HKD1_k127_3101616_17 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000001564 190.0
HKD1_k127_3101616_18 YHS domain protein - - - 0.000000000000000000000000000000217 130.0
HKD1_k127_3101616_19 - - - - 0.0000000000000000000000000729 115.0
HKD1_k127_3101616_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 4.771e-279 865.0
HKD1_k127_3101616_22 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.00000000002488 66.0
HKD1_k127_3101616_24 DDE superfamily endonuclease - - - 0.000134 44.0
HKD1_k127_3101616_25 - - - - 0.0007284 46.0
HKD1_k127_3101616_3 Iron-containing alcohol dehydrogenase - - - 1.946e-219 684.0
HKD1_k127_3101616_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 - 2.7.7.18,3.6.1.55 1.032e-203 641.0
HKD1_k127_3101616_5 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 597.0
HKD1_k127_3101616_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 529.0
HKD1_k127_3101616_7 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 503.0
HKD1_k127_3101616_8 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 492.0
HKD1_k127_3101616_9 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 488.0
HKD1_k127_310221_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.392e-278 861.0
HKD1_k127_310221_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.14e-257 799.0
HKD1_k127_310221_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.351e-254 787.0
HKD1_k127_310221_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 410.0
HKD1_k127_310221_4 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 302.0
HKD1_k127_310221_5 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000007558 116.0
HKD1_k127_3121425_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1136.0
HKD1_k127_3121425_1 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 7.463e-288 889.0
HKD1_k127_3121425_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 366.0
HKD1_k127_3121425_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 366.0
HKD1_k127_3121425_12 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 290.0
HKD1_k127_3121425_13 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000107 252.0
HKD1_k127_3121425_14 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
HKD1_k127_3121425_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000004117 201.0
HKD1_k127_3121425_16 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000001524 175.0
HKD1_k127_3121425_17 - - - - 0.00000000000000000000000000000000000000000009715 173.0
HKD1_k127_3121425_18 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000002244 157.0
HKD1_k127_3121425_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000001256 143.0
HKD1_k127_3121425_2 Luciferase-like monooxygenase - - - 3.569e-232 737.0
HKD1_k127_3121425_20 SnoaL-like domain - - - 0.000000000000000000000000002316 115.0
HKD1_k127_3121425_3 AMP-binding enzyme K12508 - 6.2.1.34 1.042e-222 692.0
HKD1_k127_3121425_4 Flavin-binding monooxygenase-like K07222 - - 1.801e-218 692.0
HKD1_k127_3121425_5 Putative serine dehydratase domain - - - 9.018e-215 682.0
HKD1_k127_3121425_6 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 509.0
HKD1_k127_3121425_8 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 400.0
HKD1_k127_3121425_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 384.0
HKD1_k127_3134400_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 292.0
HKD1_k127_3134400_1 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000002553 141.0
HKD1_k127_3134400_2 PFAM Dual specificity protein phosphatase - - - 0.000000000000000000000000000000001969 132.0
HKD1_k127_3134400_3 lactate metabolic process - - - 0.000001943 49.0
HKD1_k127_3160355_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 7.741e-199 638.0
HKD1_k127_3182857_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.585e-278 865.0
HKD1_k127_3182857_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 526.0
HKD1_k127_3182857_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 417.0
HKD1_k127_3182857_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 325.0
HKD1_k127_3182857_4 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005047 269.0
HKD1_k127_3182857_5 - - - - 0.00000000001896 66.0
HKD1_k127_3182857_6 Unextendable partial coding region - - - 0.00000000002734 65.0
HKD1_k127_3182857_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000008574 59.0
HKD1_k127_3222401_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 394.0
HKD1_k127_3222401_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 360.0
HKD1_k127_3254962_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 0.0 1247.0
HKD1_k127_3254962_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 3.95e-226 706.0
HKD1_k127_3254962_10 Protein of unknown function (DUF3574) - - - 0.00000000000000000000000000000000000000000000005556 177.0
HKD1_k127_3254962_11 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000001378 154.0
HKD1_k127_3254962_12 YCII-related domain K09780 - - 0.00000000000002181 77.0
HKD1_k127_3254962_2 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 429.0
HKD1_k127_3254962_3 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 393.0
HKD1_k127_3254962_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 373.0
HKD1_k127_3254962_5 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 373.0
HKD1_k127_3254962_6 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
HKD1_k127_3254962_7 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
HKD1_k127_3254962_8 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001117 250.0
HKD1_k127_3254962_9 Protein conserved in bacteria K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001429 248.0
HKD1_k127_3279211_0 COG0841 Cation multidrug efflux pump - - - 0.0 1763.0
HKD1_k127_3279211_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1435.0
HKD1_k127_3279211_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 571.0
HKD1_k127_3279211_11 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 554.0
HKD1_k127_3279211_12 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 537.0
HKD1_k127_3279211_13 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 490.0
HKD1_k127_3279211_14 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 479.0
HKD1_k127_3279211_15 Patatin-like phospholipase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 499.0
HKD1_k127_3279211_16 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 457.0
HKD1_k127_3279211_17 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 452.0
HKD1_k127_3279211_18 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 448.0
HKD1_k127_3279211_19 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 445.0
HKD1_k127_3279211_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.092e-304 938.0
HKD1_k127_3279211_20 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 429.0
HKD1_k127_3279211_21 Helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 402.0
HKD1_k127_3279211_22 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 386.0
HKD1_k127_3279211_23 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
HKD1_k127_3279211_24 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
HKD1_k127_3279211_25 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 305.0
HKD1_k127_3279211_26 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 299.0
HKD1_k127_3279211_27 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004391 271.0
HKD1_k127_3279211_28 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000003328 259.0
HKD1_k127_3279211_29 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000001597 207.0
HKD1_k127_3279211_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 1.288e-263 822.0
HKD1_k127_3279211_30 Transcription elongation factor, GreA/GreB, C-term K06140 - - 0.000000000000000000000000000000000000000000000000000007168 195.0
HKD1_k127_3279211_31 Belongs to the UPF0310 family - - - 0.00000000000000000000000000000000000000000000000003444 183.0
HKD1_k127_3279211_32 integral membrane protein - - - 0.0000000000000000000000000000000000000001126 157.0
HKD1_k127_3279211_33 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000005164 156.0
HKD1_k127_3279211_34 transporter solute receptor, DctP family - - - 0.0000000000000000000000000000000002302 145.0
HKD1_k127_3279211_37 ABC transporter permease - - - 0.00000002879 63.0
HKD1_k127_3279211_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.781e-257 802.0
HKD1_k127_3279211_5 FAD dependent oxidoreductase - - - 6.57e-253 784.0
HKD1_k127_3279211_6 malic enzyme K00029 - 1.1.1.40 1.588e-247 767.0
HKD1_k127_3279211_7 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.829e-207 670.0
HKD1_k127_3279211_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 617.0
HKD1_k127_3279211_9 Bacterial periplasmic substrate-binding proteins K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 578.0
HKD1_k127_3336312_0 Carboxyl transferase domain - - - 3.33e-313 963.0
HKD1_k127_3336312_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 4.792e-299 927.0
HKD1_k127_3336312_2 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 602.0
HKD1_k127_3336312_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 554.0
HKD1_k127_3336312_4 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 524.0
HKD1_k127_3336312_5 PFAM phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 524.0
HKD1_k127_3336312_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 360.0
HKD1_k127_3336312_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000001194 233.0
HKD1_k127_3336312_8 PFAM DoxX K15977 - - 0.000000000000000000005878 108.0
HKD1_k127_3336312_9 - - - - 0.00000000000000005095 81.0
HKD1_k127_3361189_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.745e-290 907.0
HKD1_k127_3361189_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.322e-274 848.0
HKD1_k127_3361189_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000002864 108.0
HKD1_k127_3361189_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.918e-254 789.0
HKD1_k127_3361189_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD1_k127_3361189_4 carbohydrate metabolic process K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 411.0
HKD1_k127_3361189_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 318.0
HKD1_k127_3361189_7 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 253.0
HKD1_k127_3361189_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000005653 239.0
HKD1_k127_3361189_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
HKD1_k127_3368431_0 TonB dependent receptor - - - 1.06e-310 967.0
HKD1_k127_3368431_1 Epoxide hydrolase N terminus K01253 - 3.3.2.9 1.17e-245 766.0
HKD1_k127_3368431_2 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 497.0
HKD1_k127_3368431_3 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 452.0
HKD1_k127_3368431_4 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 353.0
HKD1_k127_3368431_5 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002658 269.0
HKD1_k127_3368431_6 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000000000000000002049 163.0
HKD1_k127_3368431_7 YjbR - - - 0.00000000000000000000000000002846 128.0
HKD1_k127_3368577_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.382e-218 693.0
HKD1_k127_3368577_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 507.0
HKD1_k127_3368577_2 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 430.0
HKD1_k127_3368577_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 400.0
HKD1_k127_3368577_4 Retinal pigment epithelial membrane protein - - - 0.0000000000000000000000000000000000000000002126 160.0
HKD1_k127_3374524_0 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 0.0 1159.0
HKD1_k127_3374524_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.285e-298 920.0
HKD1_k127_3374524_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 601.0
HKD1_k127_3374524_11 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 535.0
HKD1_k127_3374524_12 Amino-transferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 506.0
HKD1_k127_3374524_13 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 480.0
HKD1_k127_3374524_14 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 457.0
HKD1_k127_3374524_15 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 438.0
HKD1_k127_3374524_16 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 437.0
HKD1_k127_3374524_17 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 394.0
HKD1_k127_3374524_18 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 394.0
HKD1_k127_3374524_19 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 383.0
HKD1_k127_3374524_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 2.122e-288 891.0
HKD1_k127_3374524_20 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 372.0
HKD1_k127_3374524_22 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
HKD1_k127_3374524_23 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 267.0
HKD1_k127_3374524_24 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
HKD1_k127_3374524_25 Septum formation initiator - - - 0.0000000000000000000000000000000000000000000000000001482 186.0
HKD1_k127_3374524_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000001855 175.0
HKD1_k127_3374524_27 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000000000007005 169.0
HKD1_k127_3374524_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.289e-285 881.0
HKD1_k127_3374524_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 8.069e-265 819.0
HKD1_k127_3374524_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.984e-227 710.0
HKD1_k127_3374524_6 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 7.532e-215 675.0
HKD1_k127_3374524_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 4.485e-204 662.0
HKD1_k127_3374524_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 3.553e-200 625.0
HKD1_k127_3374524_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 1.914e-199 624.0
HKD1_k127_3381778_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 481.0
HKD1_k127_3381778_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 477.0
HKD1_k127_3381778_10 - - - - 0.0000000000000000000000000000000000000000000000000001569 193.0
HKD1_k127_3381778_11 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000001218 194.0
HKD1_k127_3381778_12 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000003174 94.0
HKD1_k127_3381778_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 462.0
HKD1_k127_3381778_3 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 392.0
HKD1_k127_3381778_4 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 351.0
HKD1_k127_3381778_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 305.0
HKD1_k127_3381778_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
HKD1_k127_3381778_7 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004102 269.0
HKD1_k127_3381778_8 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000712 260.0
HKD1_k127_3381778_9 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000000000000000000000000000000004076 222.0
HKD1_k127_3388182_0 Heat shock 70 kDa protein K04043 - - 0.0 1045.0
HKD1_k127_3388182_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.443e-217 678.0
HKD1_k127_3388182_2 PFAM extracellular solute-binding protein family 5 K02035 - - 4.802e-207 656.0
HKD1_k127_3388182_3 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 464.0
HKD1_k127_3388182_4 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 453.0
HKD1_k127_3388182_5 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 417.0
HKD1_k127_3388182_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 406.0
HKD1_k127_3388182_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 382.0
HKD1_k127_340985_0 Aminotransferase class-III K01845 - 5.4.3.8 3.206e-244 758.0
HKD1_k127_340985_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 574.0
HKD1_k127_340985_2 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 436.0
HKD1_k127_340985_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
HKD1_k127_340985_4 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 376.0
HKD1_k127_340985_5 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
HKD1_k127_340985_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
HKD1_k127_340985_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004651 229.0
HKD1_k127_340985_8 - - - - 0.0000000000000000161 82.0
HKD1_k127_3424024_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1188.0
HKD1_k127_3424024_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.5e-323 991.0
HKD1_k127_3424024_10 COG0811 Biopolymer transport proteins K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 445.0
HKD1_k127_3424024_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 417.0
HKD1_k127_3424024_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 374.0
HKD1_k127_3424024_13 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 299.0
HKD1_k127_3424024_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 307.0
HKD1_k127_3424024_15 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
HKD1_k127_3424024_16 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005016 259.0
HKD1_k127_3424024_17 Ureidoglycolate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007808 241.0
HKD1_k127_3424024_18 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000002354 234.0
HKD1_k127_3424024_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000001497 237.0
HKD1_k127_3424024_2 Involved in the TonB-independent uptake of proteins K03641 - - 3.118e-238 754.0
HKD1_k127_3424024_20 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000319 230.0
HKD1_k127_3424024_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000003328 174.0
HKD1_k127_3424024_23 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000004465 174.0
HKD1_k127_3424024_25 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000002686 99.0
HKD1_k127_3424024_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 2.796e-201 629.0
HKD1_k127_3424024_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 2.797e-200 627.0
HKD1_k127_3424024_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 595.0
HKD1_k127_3424024_6 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 598.0
HKD1_k127_3424024_7 Protein conserved in bacteria K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 510.0
HKD1_k127_3424024_8 Cell division and transport-associated protein TolA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 475.0
HKD1_k127_3424024_9 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 451.0
HKD1_k127_3543282_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1050.0
HKD1_k127_3543282_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0 1009.0
HKD1_k127_3543282_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 459.0
HKD1_k127_3543282_12 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 382.0
HKD1_k127_3543282_13 COG0593 ATPase involved in DNA replication initiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 349.0
HKD1_k127_3543282_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 287.0
HKD1_k127_3543282_15 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001491 286.0
HKD1_k127_3543282_16 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001987 261.0
HKD1_k127_3543282_17 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
HKD1_k127_3543282_18 Phosphohistidine phosphatase SixA K08296 - - 0.000000000000000000000000000000000000000000000000000000000000002444 222.0
HKD1_k127_3543282_19 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003217 235.0
HKD1_k127_3543282_2 Glycosyl transferase, family 2 - - - 4.601e-299 922.0
HKD1_k127_3543282_20 NUDIX domain - - - 0.000000000000000000000000000000000000007807 153.0
HKD1_k127_3543282_21 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000001297 134.0
HKD1_k127_3543282_23 COG COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K01992,K09690 - - 0.00000000007863 73.0
HKD1_k127_3543282_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 2.92e-237 739.0
HKD1_k127_3543282_4 Putative cyclase - - - 2.536e-224 696.0
HKD1_k127_3543282_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 5.578e-195 620.0
HKD1_k127_3543282_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 611.0
HKD1_k127_3543282_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 548.0
HKD1_k127_3543282_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 543.0
HKD1_k127_3543282_9 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 501.0
HKD1_k127_3565755_0 COG0841 Cation multidrug efflux pump K18138 - - 0.0 1702.0
HKD1_k127_3565755_1 CoA-transferase family III - - - 2.493e-231 720.0
HKD1_k127_3565755_2 Belongs to the TPP enzyme family - - - 5.058e-214 671.0
HKD1_k127_3565755_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 532.0
HKD1_k127_3565755_4 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 504.0
HKD1_k127_3565755_5 the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 435.0
HKD1_k127_3565755_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 422.0
HKD1_k127_3565755_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007749 278.0
HKD1_k127_3587437_0 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 2.33e-279 865.0
HKD1_k127_3587437_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 548.0
HKD1_k127_3587437_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000002672 171.0
HKD1_k127_3591051_0 COG3839 ABC-type sugar transport systems, ATPase components - - - 2.271e-220 685.0
HKD1_k127_3591051_1 Malate/L-lactate dehydrogenase - - - 2.458e-213 664.0
HKD1_k127_3591051_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 402.0
HKD1_k127_3591051_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
HKD1_k127_3591051_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000004774 139.0
HKD1_k127_3591851_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 569.0
HKD1_k127_3591851_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 341.0
HKD1_k127_3604578_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.936e-257 797.0
HKD1_k127_3604578_1 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 2.476e-218 701.0
HKD1_k127_3604578_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 582.0
HKD1_k127_3604578_3 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 503.0
HKD1_k127_3604578_4 Transposase - - - 0.0000000000000000000000000000000000000000000000000000001635 195.0
HKD1_k127_3611212_0 DNA helicase K03657 - 3.6.4.12 0.0 1431.0
HKD1_k127_3611212_1 aminopeptidase K01262 - 3.4.11.9 0.0 1086.0
HKD1_k127_3611212_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 356.0
HKD1_k127_3611212_11 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 344.0
HKD1_k127_3611212_12 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
HKD1_k127_3611212_13 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 311.0
HKD1_k127_3611212_14 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
HKD1_k127_3611212_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000003317 284.0
HKD1_k127_3611212_16 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000002592 203.0
HKD1_k127_3611212_18 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000816 181.0
HKD1_k127_3611212_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000001667 99.0
HKD1_k127_3611212_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.551e-227 716.0
HKD1_k127_3611212_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
HKD1_k127_3611212_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 544.0
HKD1_k127_3611212_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 506.0
HKD1_k127_3611212_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 443.0
HKD1_k127_3611212_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 432.0
HKD1_k127_3611212_8 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 425.0
HKD1_k127_3611212_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
HKD1_k127_3627370_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1500.0
HKD1_k127_3627370_1 Elongation factor SelB, winged helix K03833 - - 0.0 1067.0
HKD1_k127_3627370_10 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 441.0
HKD1_k127_3627370_11 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 408.0
HKD1_k127_3627370_12 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 359.0
HKD1_k127_3627370_13 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
HKD1_k127_3627370_14 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 352.0
HKD1_k127_3627370_15 Cell division protein ZipA - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
HKD1_k127_3627370_16 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
HKD1_k127_3627370_17 Ring hydroxylating beta subunit K15750 - 1.14.12.18 0.00000000000000000000000000000000000000000000000000000000258 208.0
HKD1_k127_3627370_18 Haem-degrading - - - 0.000000000000000000000000000000000000003273 152.0
HKD1_k127_3627370_19 TIGRFAM Outer membrane protein - - - 0.000000000000000000000000000000000000007839 164.0
HKD1_k127_3627370_2 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 1.445e-234 732.0
HKD1_k127_3627370_20 - - - - 0.0000000000000000000000000000000000009994 151.0
HKD1_k127_3627370_21 - - - - 0.000000000000000000000000000000000264 141.0
HKD1_k127_3627370_22 Prophage CP4-57 regulatory protein (AlpA) - - - 0.000000000000000000000000003364 111.0
HKD1_k127_3627370_23 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000002034 100.0
HKD1_k127_3627370_24 - - - - 0.000000007029 68.0
HKD1_k127_3627370_3 - - - - 3.136e-206 647.0
HKD1_k127_3627370_4 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 591.0
HKD1_k127_3627370_5 Allophanate hydrolase subunit 2 K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 571.0
HKD1_k127_3627370_6 Ring hydroxylating alpha subunit (catalytic domain) K03268,K05708 - 1.14.12.11,1.14.12.19,1.14.12.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 531.0
HKD1_k127_3627370_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 531.0
HKD1_k127_3627370_8 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 475.0
HKD1_k127_3627370_9 DNA integration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 452.0
HKD1_k127_3696851_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1367.0
HKD1_k127_3696851_1 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 324.0
HKD1_k127_3696851_2 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005357 263.0
HKD1_k127_3715275_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1049.0
HKD1_k127_3715275_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 600.0
HKD1_k127_3715275_11 PFAM Flp Fap pilin component K02651 - - 0.00008055 46.0
HKD1_k127_3715275_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 561.0
HKD1_k127_3715275_4 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 477.0
HKD1_k127_3715275_5 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 314.0
HKD1_k127_3715275_6 HeAt shock protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003723 276.0
HKD1_k127_3715275_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001149 217.0
HKD1_k127_3715275_8 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000006569 186.0
HKD1_k127_3715275_9 FecR protein - - - 0.000000000000000000000000005088 130.0
HKD1_k127_3750992_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1344.0
HKD1_k127_3750992_1 Threonine synthase K01733 - 4.2.3.1 3.444e-269 837.0
HKD1_k127_3750992_10 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 376.0
HKD1_k127_3750992_11 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 383.0
HKD1_k127_3750992_12 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000008949 223.0
HKD1_k127_3750992_13 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000000000000000000001122 179.0
HKD1_k127_3750992_15 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000007173 75.0
HKD1_k127_3750992_2 Belongs to the peptidase M16 family - - - 5.364e-253 782.0
HKD1_k127_3750992_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 507.0
HKD1_k127_3750992_4 Catechol dioxygenase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 504.0
HKD1_k127_3750992_5 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 480.0
HKD1_k127_3750992_6 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 403.0
HKD1_k127_3750992_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 396.0
HKD1_k127_3750992_8 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 379.0
HKD1_k127_3750992_9 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 383.0
HKD1_k127_378093_0 - - - - 3.391e-196 615.0
HKD1_k127_378093_1 NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 598.0
HKD1_k127_378093_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 409.0
HKD1_k127_378093_11 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 304.0
HKD1_k127_378093_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000000000000001596 231.0
HKD1_k127_378093_13 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000002463 171.0
HKD1_k127_378093_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000005647 172.0
HKD1_k127_378093_15 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000006547 153.0
HKD1_k127_378093_17 NUDIX domain - - - 0.000000000000000000000002064 111.0
HKD1_k127_378093_18 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000002081 99.0
HKD1_k127_378093_2 Major Facilitator Superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 602.0
HKD1_k127_378093_21 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000002586 57.0
HKD1_k127_378093_22 Protein of unknown function (DUF465) K09794 - - 0.0000000613 65.0
HKD1_k127_378093_23 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.000003853 59.0
HKD1_k127_378093_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 545.0
HKD1_k127_378093_4 FAD binding domain K00480,K14974 - 1.14.13.1,1.14.13.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 538.0
HKD1_k127_378093_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 509.0
HKD1_k127_378093_6 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
HKD1_k127_378093_7 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 481.0
HKD1_k127_378093_8 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
HKD1_k127_378093_9 Biotin-lipoyl like K03543,K15549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 420.0
HKD1_k127_3799706_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1216.0
HKD1_k127_3799706_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.701e-293 906.0
HKD1_k127_3799706_2 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 484.0
HKD1_k127_3799706_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 458.0
HKD1_k127_3799706_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 338.0
HKD1_k127_3799706_5 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000003075 248.0
HKD1_k127_3799706_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
HKD1_k127_3799706_7 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.000000000000000000000000000000000000000000000000000000004485 202.0
HKD1_k127_3799706_8 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000000000000000000000000001324 155.0
HKD1_k127_3801581_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 2.928e-242 755.0
HKD1_k127_3801581_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.328e-200 627.0
HKD1_k127_3801581_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 624.0
HKD1_k127_3801581_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 458.0
HKD1_k127_3805326_0 Psort location Cytoplasmic, score 7.50 - - - 6.367e-230 716.0
HKD1_k127_3805326_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 587.0
HKD1_k127_3805326_11 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000006465 79.0
HKD1_k127_3805326_12 PFAM Uncharacterised protein family UPF0150 - - - 0.00001179 52.0
HKD1_k127_3805326_13 ATPase with chaperone activity K07391 - - 0.0003987 44.0
HKD1_k127_3805326_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 544.0
HKD1_k127_3805326_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 458.0
HKD1_k127_3805326_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 472.0
HKD1_k127_3805326_5 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 413.0
HKD1_k127_3805326_6 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 413.0
HKD1_k127_3805326_7 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
HKD1_k127_3805326_8 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000000000000000000001011 212.0
HKD1_k127_3805326_9 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000004932 150.0
HKD1_k127_3897156_0 oligoendopeptidase F K08602 - - 0.0 1093.0
HKD1_k127_3897156_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.513e-319 980.0
HKD1_k127_3897156_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 373.0
HKD1_k127_3897156_11 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 326.0
HKD1_k127_3897156_12 Protein of unknown function (DUF2390) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 290.0
HKD1_k127_3897156_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006909 272.0
HKD1_k127_3897156_15 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001166 231.0
HKD1_k127_3897156_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
HKD1_k127_3897156_17 Vancomycin high temperature exclusion protein K03748 - - 0.000000000000000000000000000000000000000000000000000000000002128 236.0
HKD1_k127_3897156_18 COQ9 K18587 - - 0.000000000000000000000000000000000000000000000000000000006499 205.0
HKD1_k127_3897156_19 GAF domain - - - 0.000000000000000000000000000000000000008113 156.0
HKD1_k127_3897156_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.697e-264 827.0
HKD1_k127_3897156_20 - - - - 0.0000000000000000000000000000000000006439 161.0
HKD1_k127_3897156_21 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000000006293 139.0
HKD1_k127_3897156_22 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000001171 119.0
HKD1_k127_3897156_23 Protein of unknown function (DUF465) - - - 0.000000000000000000000000005092 111.0
HKD1_k127_3897156_24 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000002352 102.0
HKD1_k127_3897156_3 ABC1 family - - - 9.988e-260 803.0
HKD1_k127_3897156_4 Amidohydrolase family - - - 1.149e-228 718.0
HKD1_k127_3897156_5 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 6.436e-206 647.0
HKD1_k127_3897156_6 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 557.0
HKD1_k127_3897156_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 545.0
HKD1_k127_3897156_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 541.0
HKD1_k127_3897156_9 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 535.0
HKD1_k127_3909962_0 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 2.633e-310 968.0
HKD1_k127_3909962_1 Belongs to the amidase family K01426 - 3.5.1.4 9.1e-307 943.0
HKD1_k127_3909962_10 Branched-chain amino acid ATP-binding cassette transporter K01995,K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 430.0
HKD1_k127_3909962_11 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 400.0
HKD1_k127_3909962_12 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 295.0
HKD1_k127_3909962_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 286.0
HKD1_k127_3909962_14 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003571 263.0
HKD1_k127_3909962_15 Protein of unknown function (DUF1467) - - - 0.000000000000000000000000000000000001419 139.0
HKD1_k127_3909962_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 6.062e-297 914.0
HKD1_k127_3909962_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.682e-263 818.0
HKD1_k127_3909962_4 Periplasmic binding protein domain K11959 - - 2.691e-251 785.0
HKD1_k127_3909962_5 Permease family K06901 - - 1.979e-225 706.0
HKD1_k127_3909962_6 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 3.494e-219 688.0
HKD1_k127_3909962_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 571.0
HKD1_k127_3909962_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 545.0
HKD1_k127_3909962_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 506.0
HKD1_k127_3910799_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 1.483e-293 912.0
HKD1_k127_3910799_1 malate quinone oxidoreductase K00116 - 1.1.5.4 5.526e-282 876.0
HKD1_k127_3910799_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 571.0
HKD1_k127_3910799_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 549.0
HKD1_k127_3910799_12 xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 531.0
HKD1_k127_3910799_13 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 497.0
HKD1_k127_3910799_14 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 491.0
HKD1_k127_3910799_15 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 476.0
HKD1_k127_3910799_16 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 477.0
HKD1_k127_3910799_17 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 493.0
HKD1_k127_3910799_18 Putative threonine/serine exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 468.0
HKD1_k127_3910799_19 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 443.0
HKD1_k127_3910799_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 8.443e-276 851.0
HKD1_k127_3910799_20 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 441.0
HKD1_k127_3910799_21 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 415.0
HKD1_k127_3910799_22 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 424.0
HKD1_k127_3910799_23 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 407.0
HKD1_k127_3910799_24 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 392.0
HKD1_k127_3910799_25 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 369.0
HKD1_k127_3910799_26 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 348.0
HKD1_k127_3910799_27 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 332.0
HKD1_k127_3910799_28 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 312.0
HKD1_k127_3910799_29 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002254 270.0
HKD1_k127_3910799_3 Binding-protein-dependent transport system inner membrane component K02011 - - 1.288e-261 817.0
HKD1_k127_3910799_30 Ferredoxin, 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 228.0
HKD1_k127_3910799_31 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002501 225.0
HKD1_k127_3910799_32 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000008419 228.0
HKD1_k127_3910799_33 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000006179 238.0
HKD1_k127_3910799_34 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006696 218.0
HKD1_k127_3910799_35 RF-1 domain K15034 - - 0.0000000000000000000000000000000000000000000000000000000000001399 214.0
HKD1_k127_3910799_36 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000005333 204.0
HKD1_k127_3910799_37 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000001547 192.0
HKD1_k127_3910799_38 Ankyrin repeats (3 copies) K06867 - - 0.0000000000000000000000000000000000000000000000000001777 198.0
HKD1_k127_3910799_39 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000000000000001993 197.0
HKD1_k127_3910799_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 1.631e-259 824.0
HKD1_k127_3910799_40 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000002491 194.0
HKD1_k127_3910799_41 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000001471 187.0
HKD1_k127_3910799_42 domain, Protein - - - 0.0000000000000000000000000000000000000000000001228 168.0
HKD1_k127_3910799_43 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000008249 143.0
HKD1_k127_3910799_44 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000005108 125.0
HKD1_k127_3910799_45 SpoVT / AbrB like domain - - - 0.000000000000000000000000003183 112.0
HKD1_k127_3910799_46 Protein of unknown function (DUF1275) - - - 0.0000000000000000000008936 104.0
HKD1_k127_3910799_47 Membrane - - - 0.0000000000000000000009651 103.0
HKD1_k127_3910799_48 REDY-like protein HapK - - - 0.00000126 54.0
HKD1_k127_3910799_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 4.367e-218 681.0
HKD1_k127_3910799_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.973e-205 653.0
HKD1_k127_3910799_7 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 596.0
HKD1_k127_3910799_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 578.0
HKD1_k127_3910799_9 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 574.0
HKD1_k127_3912519_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0 1030.0
HKD1_k127_3912519_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0 1020.0
HKD1_k127_3912519_10 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 435.0
HKD1_k127_3912519_11 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 399.0
HKD1_k127_3912519_12 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 388.0
HKD1_k127_3912519_13 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
HKD1_k127_3912519_14 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 291.0
HKD1_k127_3912519_15 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001701 218.0
HKD1_k127_3912519_16 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000007384 177.0
HKD1_k127_3912519_17 Universal stress protein family - - - 0.000000000000000000000000000000000000000005219 160.0
HKD1_k127_3912519_18 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000003824 164.0
HKD1_k127_3912519_19 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000003921 153.0
HKD1_k127_3912519_2 E1-E2 ATPase K01535 - 3.6.3.6 9.996e-299 945.0
HKD1_k127_3912519_20 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000004904 123.0
HKD1_k127_3912519_21 Carbamoyl-phosphate synthase L chain ATP-binding K01965 - 6.4.1.3 0.000000000000000000000003024 106.0
HKD1_k127_3912519_22 Phosphopantetheine attachment site - - - 0.0000000000000000000002307 100.0
HKD1_k127_3912519_3 COG1960 Acyl-CoA dehydrogenases - - - 7.047e-217 677.0
HKD1_k127_3912519_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 559.0
HKD1_k127_3912519_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 560.0
HKD1_k127_3912519_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 561.0
HKD1_k127_3912519_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 514.0
HKD1_k127_3912519_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 511.0
HKD1_k127_3912519_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 455.0
HKD1_k127_3962958_0 COG0457 FOG TPR repeat - - - 3.724e-281 871.0
HKD1_k127_3962958_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 3.69e-200 631.0
HKD1_k127_3962958_10 - - - - 0.00000000000000000000000000000000000000000000114 180.0
HKD1_k127_3962958_11 Cell division protein K03591,K03749 - - 0.000000000000000000000000000003527 132.0
HKD1_k127_3962958_13 Resolvase, N terminal domain - - - 0.000000000003366 69.0
HKD1_k127_3962958_2 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 439.0
HKD1_k127_3962958_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 416.0
HKD1_k127_3962958_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 393.0
HKD1_k127_3962958_5 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 348.0
HKD1_k127_3962958_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 328.0
HKD1_k127_3962958_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006632 277.0
HKD1_k127_3962958_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
HKD1_k127_3962958_9 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001664 207.0
HKD1_k127_3969428_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.355e-262 820.0
HKD1_k127_3969428_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 516.0
HKD1_k127_3969428_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 518.0
HKD1_k127_3969428_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 505.0
HKD1_k127_3969428_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 489.0
HKD1_k127_3969428_5 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 384.0
HKD1_k127_3969428_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 274.0
HKD1_k127_3969428_7 AMP-binding enzyme K12508 - 6.2.1.34 0.000000000000008564 88.0
HKD1_k127_3969428_8 Transposase IS116/IS110/IS902 family K07486 - - 0.00000001316 55.0
HKD1_k127_3986434_0 FAD dependent oxidoreductase - - - 0.0 1554.0
HKD1_k127_3986434_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 2.491e-277 858.0
HKD1_k127_3986434_10 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 602.0
HKD1_k127_3986434_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 544.0
HKD1_k127_3986434_12 amidinotransferase K00613 - 2.1.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 537.0
HKD1_k127_3986434_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 456.0
HKD1_k127_3986434_14 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 484.0
HKD1_k127_3986434_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 438.0
HKD1_k127_3986434_16 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000007681 235.0
HKD1_k127_3986434_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.276e-275 851.0
HKD1_k127_3986434_3 Na+/Pi-cotransporter K03324 - - 4.856e-268 834.0
HKD1_k127_3986434_4 Glycosyl transferase family group 2 - - - 1.321e-239 745.0
HKD1_k127_3986434_5 Iron-containing alcohol dehydrogenase - - - 6.108e-226 704.0
HKD1_k127_3986434_6 Glycosyl transferase, family 2 - - - 8.571e-223 695.0
HKD1_k127_3986434_7 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 4.323e-213 665.0
HKD1_k127_3986434_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.378e-196 631.0
HKD1_k127_3986434_9 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 607.0
HKD1_k127_400973_0 Epoxide hydrolase N terminus K21159 - - 4.945e-226 706.0
HKD1_k127_400973_1 reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 587.0
HKD1_k127_400973_2 TfoX N-terminal domain K07343 - - 0.000000000000000000000000000000000000000000000001066 199.0
HKD1_k127_4084473_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0 1066.0
HKD1_k127_4084473_1 Glycosyltransferase family 28 C-terminal domain - - - 0.0 1033.0
HKD1_k127_4084473_10 Proline racemase K12658 - 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 541.0
HKD1_k127_4084473_11 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 512.0
HKD1_k127_4084473_12 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 497.0
HKD1_k127_4084473_13 Oxidoreductase NAD-binding domain K00380,K02641,K14338 - 1.14.14.1,1.18.1.2,1.6.2.4,1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 503.0
HKD1_k127_4084473_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 454.0
HKD1_k127_4084473_15 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
HKD1_k127_4084473_16 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 449.0
HKD1_k127_4084473_17 ABC transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 429.0
HKD1_k127_4084473_18 ABC transporter K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 407.0
HKD1_k127_4084473_19 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 404.0
HKD1_k127_4084473_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 1.657e-303 958.0
HKD1_k127_4084473_20 Binding-protein-dependent transport system inner membrane component K02050,K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 412.0
HKD1_k127_4084473_21 NMT1-like family K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 386.0
HKD1_k127_4084473_22 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 368.0
HKD1_k127_4084473_23 Protein of unknown function (DUF2848) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 327.0
HKD1_k127_4084473_24 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 294.0
HKD1_k127_4084473_25 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 291.0
HKD1_k127_4084473_26 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008887 268.0
HKD1_k127_4084473_27 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
HKD1_k127_4084473_28 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000001093 190.0
HKD1_k127_4084473_29 response regulator receiver K07183 - - 0.00000000000000000000000000000000000000000000000005756 184.0
HKD1_k127_4084473_3 Sulfatase - - - 4.049e-291 903.0
HKD1_k127_4084473_30 Shikimate kinase - - - 0.00000000000000000000000000000000000000000003224 168.0
HKD1_k127_4084473_31 PFAM amidohydrolase K07045 - - 0.0000000000000002403 78.0
HKD1_k127_4084473_4 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.888e-278 862.0
HKD1_k127_4084473_5 serine threonine protein kinase K08282 - 2.7.11.1 1.037e-275 859.0
HKD1_k127_4084473_6 CoA-transferase family III - - - 1.033e-240 746.0
HKD1_k127_4084473_7 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 2.464e-204 647.0
HKD1_k127_4084473_8 PFAM nitrite and sulphite reductase 4Fe-4S K00366 - 1.7.7.1 2.479e-203 661.0
HKD1_k127_4084473_9 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 594.0
HKD1_k127_4091407_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 4.224e-228 708.0
HKD1_k127_4091407_1 Receptor family ligand binding region K01999 - - 1.019e-211 664.0
HKD1_k127_4091407_10 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000009183 223.0
HKD1_k127_4091407_11 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000002428 100.0
HKD1_k127_4091407_12 Response regulator receiver - - - 0.00000000000000001447 91.0
HKD1_k127_4091407_13 - - - - 0.00000000000000002775 88.0
HKD1_k127_4091407_14 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000005514 89.0
HKD1_k127_4091407_15 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18303,K21134 - - 0.00000003639 65.0
HKD1_k127_4091407_16 Response regulator receiver - - - 0.0000537 52.0
HKD1_k127_4091407_2 CoA-transferase family III - - - 1.509e-200 638.0
HKD1_k127_4091407_3 N-terminal domain of oxidoreductase K07119 - - 2.061e-196 616.0
HKD1_k127_4091407_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 547.0
HKD1_k127_4091407_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 509.0
HKD1_k127_4091407_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 494.0
HKD1_k127_4091407_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 456.0
HKD1_k127_4091407_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 405.0
HKD1_k127_4091407_9 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 327.0
HKD1_k127_410904_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1363.0
HKD1_k127_410904_1 Hydantoinase B/oxoprolinase - - - 0.0 1069.0
HKD1_k127_410904_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 9.301e-255 791.0
HKD1_k127_410904_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 548.0
HKD1_k127_410904_4 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 522.0
HKD1_k127_410904_5 oxidase, subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000007689 231.0
HKD1_k127_410904_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K05712,K20218 - 1.14.13.127 0.0000002615 54.0
HKD1_k127_412712_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.4e-323 992.0
HKD1_k127_412712_1 AMP-binding enzyme K00666 - - 6.372e-309 955.0
HKD1_k127_412712_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 602.0
HKD1_k127_412712_11 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 535.0
HKD1_k127_412712_12 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 522.0
HKD1_k127_412712_13 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 524.0
HKD1_k127_412712_14 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 503.0
HKD1_k127_412712_15 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 452.0
HKD1_k127_412712_16 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 446.0
HKD1_k127_412712_17 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 393.0
HKD1_k127_412712_18 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 390.0
HKD1_k127_412712_19 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 383.0
HKD1_k127_412712_2 Cys/Met metabolism PLP-dependent enzyme K00652,K00654 - 2.3.1.47,2.3.1.50 9.459e-244 756.0
HKD1_k127_412712_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 377.0
HKD1_k127_412712_21 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 377.0
HKD1_k127_412712_22 Abc-type multidrug transport system, permease component K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 356.0
HKD1_k127_412712_23 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 334.0
HKD1_k127_412712_24 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HKD1_k127_412712_25 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 290.0
HKD1_k127_412712_26 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002403 275.0
HKD1_k127_412712_27 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000472 273.0
HKD1_k127_412712_29 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
HKD1_k127_412712_3 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 1.73e-240 747.0
HKD1_k127_412712_30 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
HKD1_k127_412712_31 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000000000000000000000000000000001298 203.0
HKD1_k127_412712_32 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000006114 198.0
HKD1_k127_412712_33 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000009472 194.0
HKD1_k127_412712_34 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000003328 178.0
HKD1_k127_412712_35 Cytochrome c - - - 0.0000000000000000000000000000000000000000000008635 174.0
HKD1_k127_412712_36 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000002165 147.0
HKD1_k127_412712_37 NIPSNAP - - - 0.0000000000000000000000000000000004082 136.0
HKD1_k127_412712_38 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000002173 66.0
HKD1_k127_412712_39 Cation efflux family - - - 0.00000000002717 66.0
HKD1_k127_412712_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.324e-233 739.0
HKD1_k127_412712_40 Cation efflux family - - - 0.000000003481 67.0
HKD1_k127_412712_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 1.38e-230 718.0
HKD1_k127_412712_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 6.13e-222 691.0
HKD1_k127_412712_7 III protein, CoA-transferase family K07749 - 2.8.3.16 4.415e-214 670.0
HKD1_k127_412712_8 OpgC protein - - - 8.416e-196 615.0
HKD1_k127_412712_9 pfam abc K01990,K01992,K09695 - - 7.173e-195 629.0
HKD1_k127_4164473_0 DNA invertase Pin - - - 0.0 1124.0
HKD1_k127_4164473_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 2.066e-229 717.0
HKD1_k127_4164473_10 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 470.0
HKD1_k127_4164473_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 427.0
HKD1_k127_4164473_12 AMP-binding enzyme K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 440.0
HKD1_k127_4164473_13 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 408.0
HKD1_k127_4164473_14 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 407.0
HKD1_k127_4164473_15 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 362.0
HKD1_k127_4164473_16 insertion sequence ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 340.0
HKD1_k127_4164473_17 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 340.0
HKD1_k127_4164473_18 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
HKD1_k127_4164473_19 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
HKD1_k127_4164473_2 trisaccharide binding - - - 1.26e-211 687.0
HKD1_k127_4164473_20 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 317.0
HKD1_k127_4164473_21 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 318.0
HKD1_k127_4164473_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
HKD1_k127_4164473_23 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 271.0
HKD1_k127_4164473_24 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 255.0
HKD1_k127_4164473_25 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005418 263.0
HKD1_k127_4164473_26 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000001821 233.0
HKD1_k127_4164473_27 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
HKD1_k127_4164473_28 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 237.0
HKD1_k127_4164473_29 - - - - 0.000000000000000000000000000000000000000000000000000000000001819 239.0
HKD1_k127_4164473_3 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 538.0
HKD1_k127_4164473_30 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
HKD1_k127_4164473_31 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000007451 194.0
HKD1_k127_4164473_32 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000003315 206.0
HKD1_k127_4164473_33 ArsC family - - - 0.0000000000000000000000000000000000000000000000000004095 194.0
HKD1_k127_4164473_34 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000000000000009951 170.0
HKD1_k127_4164473_35 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000001922 179.0
HKD1_k127_4164473_36 - - - - 0.000000000000000000000000000000000000000003758 160.0
HKD1_k127_4164473_37 Oxidoreductase K19336 - - 0.0000000000000000000000000000000000000001753 162.0
HKD1_k127_4164473_39 PFAM Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000001053 143.0
HKD1_k127_4164473_4 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 515.0
HKD1_k127_4164473_40 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000002417 135.0
HKD1_k127_4164473_41 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000004127 126.0
HKD1_k127_4164473_42 Family of unknown function (DUF5372) - - - 0.00000000000000000000000000531 113.0
HKD1_k127_4164473_43 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000003157 117.0
HKD1_k127_4164473_44 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.00000000000000000000004537 104.0
HKD1_k127_4164473_45 glyoxalase K06996 - - 0.00000000000261 68.0
HKD1_k127_4164473_46 - - - - 0.00000000002738 67.0
HKD1_k127_4164473_47 - - - - 0.0000009654 59.0
HKD1_k127_4164473_5 Dyp-type peroxidase family K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 520.0
HKD1_k127_4164473_6 Nitrilotriacetate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 524.0
HKD1_k127_4164473_7 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 477.0
HKD1_k127_4164473_8 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 468.0
HKD1_k127_4164473_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 471.0
HKD1_k127_4185290_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1982.0
HKD1_k127_4185290_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 602.0
HKD1_k127_4185290_2 Histidine phosphatase superfamily (branch 2) K01093 - 3.1.3.2,3.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 518.0
HKD1_k127_4185290_3 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 436.0
HKD1_k127_4185290_5 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12262 - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
HKD1_k127_4185290_6 Protein of unknown function (DUF1254) - - - 0.000000000000000000000002815 103.0
HKD1_k127_4190627_0 transport systems, ATPase components K02056 - 3.6.3.17 1.719e-248 775.0
HKD1_k127_4190627_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 558.0
HKD1_k127_4190627_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HKD1_k127_4200342_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 1.781e-213 684.0
HKD1_k127_4200342_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 601.0
HKD1_k127_4200342_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 538.0
HKD1_k127_4200342_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 525.0
HKD1_k127_4200342_4 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 461.0
HKD1_k127_4200342_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 439.0
HKD1_k127_4200342_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 446.0
HKD1_k127_4200342_7 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000000000000000000000008617 247.0
HKD1_k127_4200342_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000001054 132.0
HKD1_k127_4209163_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1192.0
HKD1_k127_4209163_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 568.0
HKD1_k127_4209163_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 416.0
HKD1_k127_4209163_3 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 411.0
HKD1_k127_4209163_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 338.0
HKD1_k127_4209163_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 297.0
HKD1_k127_4209163_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001079 267.0
HKD1_k127_4216903_0 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
HKD1_k127_4216903_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002148 249.0
HKD1_k127_4216903_2 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000002763 203.0
HKD1_k127_4222827_0 Aldehyde dehydrogenase family - - - 1.969e-290 897.0
HKD1_k127_4222827_1 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 587.0
HKD1_k127_4222827_2 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 465.0
HKD1_k127_4222827_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000004483 209.0
HKD1_k127_4222827_4 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
HKD1_k127_4222827_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000007689 154.0
HKD1_k127_4223185_0 Rieske 2Fe-2S domain protein K14748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 560.0
HKD1_k127_4223185_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 406.0
HKD1_k127_4223185_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
HKD1_k127_4223185_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000001241 71.0
HKD1_k127_4230858_0 COG0841 Cation multidrug efflux pump K03296 - - 0.0 1655.0
HKD1_k127_4230858_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1294.0
HKD1_k127_4230858_10 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 551.0
HKD1_k127_4230858_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 535.0
HKD1_k127_4230858_12 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 514.0
HKD1_k127_4230858_13 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 502.0
HKD1_k127_4230858_14 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 - 1.14.99.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 494.0
HKD1_k127_4230858_15 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 409.0
HKD1_k127_4230858_16 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 388.0
HKD1_k127_4230858_17 ABC-type dipeptide transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 412.0
HKD1_k127_4230858_18 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 392.0
HKD1_k127_4230858_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 350.0
HKD1_k127_4230858_2 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1223.0
HKD1_k127_4230858_20 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 335.0
HKD1_k127_4230858_21 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
HKD1_k127_4230858_22 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 318.0
HKD1_k127_4230858_24 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 296.0
HKD1_k127_4230858_25 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 312.0
HKD1_k127_4230858_26 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 304.0
HKD1_k127_4230858_27 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 295.0
HKD1_k127_4230858_28 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
HKD1_k127_4230858_29 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000003346 232.0
HKD1_k127_4230858_3 Conserved region in glutamate synthase - - - 1.414e-291 908.0
HKD1_k127_4230858_30 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000001808 237.0
HKD1_k127_4230858_31 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 - - 0.00000000000000000000000000000000000000000000000000000000002644 222.0
HKD1_k127_4230858_32 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000002281 202.0
HKD1_k127_4230858_33 transport system permease component - - - 0.000000000000000000000000000000000000000000000003852 191.0
HKD1_k127_4230858_34 PFAM Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000003835 136.0
HKD1_k127_4230858_35 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000001133 129.0
HKD1_k127_4230858_36 Response regulator receiver - - - 0.00000000000000000008609 94.0
HKD1_k127_4230858_4 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 2.686e-289 895.0
HKD1_k127_4230858_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 1.686e-243 769.0
HKD1_k127_4230858_6 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 5.711e-243 754.0
HKD1_k127_4230858_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.151e-226 712.0
HKD1_k127_4230858_8 FAD binding domain - - - 3.45e-213 670.0
HKD1_k127_4230858_9 monooxygenase K09018 - 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 557.0
HKD1_k127_4237547_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 5.128e-263 817.0
HKD1_k127_4237547_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.667e-228 710.0
HKD1_k127_4237547_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 460.0
HKD1_k127_4237547_11 KR domain K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 455.0
HKD1_k127_4237547_12 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 455.0
HKD1_k127_4237547_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 440.0
HKD1_k127_4237547_14 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 421.0
HKD1_k127_4237547_15 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 403.0
HKD1_k127_4237547_16 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 402.0
HKD1_k127_4237547_17 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 358.0
HKD1_k127_4237547_18 PHB de-polymerase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 355.0
HKD1_k127_4237547_19 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 349.0
HKD1_k127_4237547_2 Chromate transporter K07240 - - 1.378e-212 669.0
HKD1_k127_4237547_20 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 346.0
HKD1_k127_4237547_21 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 314.0
HKD1_k127_4237547_22 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 324.0
HKD1_k127_4237547_23 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 317.0
HKD1_k127_4237547_24 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 293.0
HKD1_k127_4237547_25 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 288.0
HKD1_k127_4237547_26 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K19743 - 1.4.1.1,1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 300.0
HKD1_k127_4237547_27 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
HKD1_k127_4237547_28 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 291.0
HKD1_k127_4237547_29 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
HKD1_k127_4237547_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 9.817e-203 637.0
HKD1_k127_4237547_30 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001116 285.0
HKD1_k127_4237547_31 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000915 261.0
HKD1_k127_4237547_32 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000147 247.0
HKD1_k127_4237547_33 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003817 244.0
HKD1_k127_4237547_34 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
HKD1_k127_4237547_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000006608 237.0
HKD1_k127_4237547_36 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000002135 186.0
HKD1_k127_4237547_38 - - - - 0.00000000000000000000000000000000000833 147.0
HKD1_k127_4237547_4 Patatin phospholipase K07001 - - 5.377e-196 616.0
HKD1_k127_4237547_40 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000002785 138.0
HKD1_k127_4237547_41 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000002461 130.0
HKD1_k127_4237547_42 Globin - - - 0.00000000000000000000000000002008 124.0
HKD1_k127_4237547_43 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000005548 125.0
HKD1_k127_4237547_46 - - - - 0.00000000000000000005343 98.0
HKD1_k127_4237547_47 TIR domain - - - 0.000000000000000001945 97.0
HKD1_k127_4237547_49 chlorophyll binding - - - 0.00000000000004987 83.0
HKD1_k127_4237547_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 514.0
HKD1_k127_4237547_50 Protein of unknown function (DUF3299) - - - 0.00000000000037 76.0
HKD1_k127_4237547_51 DNA ligase K01971 - 6.5.1.1 0.00000003371 58.0
HKD1_k127_4237547_52 - - - - 0.000001378 53.0
HKD1_k127_4237547_6 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 509.0
HKD1_k127_4237547_7 taurine catabolism dioxygenase K03119,K22303 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 507.0
HKD1_k127_4237547_8 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 484.0
HKD1_k127_4237547_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 467.0
HKD1_k127_4240799_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1234.0
HKD1_k127_4240799_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.755e-300 923.0
HKD1_k127_4240799_10 2-oxohepta-3-ene-1,7-dioic acid hydratase K01617,K02509 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 362.0
HKD1_k127_4240799_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007268 274.0
HKD1_k127_4240799_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
HKD1_k127_4240799_13 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000395 183.0
HKD1_k127_4240799_15 transcriptional regulator - - - 0.000000000000000000004531 104.0
HKD1_k127_4240799_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.839e-265 822.0
HKD1_k127_4240799_3 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 4.125e-205 649.0
HKD1_k127_4240799_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 511.0
HKD1_k127_4240799_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 489.0
HKD1_k127_4240799_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 446.0
HKD1_k127_4240799_7 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 434.0
HKD1_k127_4240799_8 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 415.0
HKD1_k127_4240799_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 410.0
HKD1_k127_4241256_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1231.0
HKD1_k127_4241256_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.312e-317 974.0
HKD1_k127_4241256_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 331.0
HKD1_k127_4241256_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002316 242.0
HKD1_k127_4241256_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000001206 170.0
HKD1_k127_4241256_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000003176 156.0
HKD1_k127_4241256_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.504e-281 865.0
HKD1_k127_4241256_3 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 6.376e-264 816.0
HKD1_k127_4241256_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 8.533e-251 784.0
HKD1_k127_4241256_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 3.246e-211 657.0
HKD1_k127_4241256_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 364.0
HKD1_k127_4241256_7 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 354.0
HKD1_k127_4241256_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 339.0
HKD1_k127_4241256_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 312.0
HKD1_k127_4266420_0 Psort location Cytoplasmic, score 7.50 - - - 4.658e-234 730.0
HKD1_k127_4266420_1 Major Facilitator - - - 2.915e-206 659.0
HKD1_k127_4266420_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 599.0
HKD1_k127_4266420_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
HKD1_k127_4266420_4 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
HKD1_k127_4266420_5 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 293.0
HKD1_k127_4266420_6 - - - - 0.000000000000000000000000000000000000000000000000000000000008752 228.0
HKD1_k127_4266420_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000002499 183.0
HKD1_k127_4266420_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000002725 139.0
HKD1_k127_4266420_9 - - - - 0.00000000000000000000000000000008163 131.0
HKD1_k127_4267086_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 2.441e-216 674.0
HKD1_k127_4267086_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 595.0
HKD1_k127_4267086_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 467.0
HKD1_k127_4267086_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 343.0
HKD1_k127_4267086_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
HKD1_k127_4267086_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 308.0
HKD1_k127_4267086_6 Protein conserved in bacteria K09962 - - 0.00000000000008086 74.0
HKD1_k127_4274664_0 single-stranded-DNA-specific exonuclease recJ K07462 - - 0.0 1041.0
HKD1_k127_4274664_1 Resolvase, N terminal domain - - - 5.399e-241 755.0
HKD1_k127_4274664_10 Belongs to the ompA family - - - 0.00000000000000000000000000001601 123.0
HKD1_k127_4274664_11 integral membrane protein - - - 0.0000000000000000000004238 99.0
HKD1_k127_4274664_12 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000001094 94.0
HKD1_k127_4274664_13 - - - - 0.0000000000002069 83.0
HKD1_k127_4274664_14 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000006023 67.0
HKD1_k127_4274664_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 545.0
HKD1_k127_4274664_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 520.0
HKD1_k127_4274664_4 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 488.0
HKD1_k127_4274664_5 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 444.0
HKD1_k127_4274664_6 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
HKD1_k127_4274664_7 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001238 245.0
HKD1_k127_4274664_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000005572 196.0
HKD1_k127_4274664_9 DoxX K15977 - - 0.0000000000000000000000000000000000587 145.0
HKD1_k127_427507_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0 1042.0
HKD1_k127_427507_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004326 303.0
HKD1_k127_427507_2 Flavoprotein K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000002218 265.0
HKD1_k127_427507_4 Protein of unknown function (DUF465) - - - 0.00000000000000000001152 93.0
HKD1_k127_4303536_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0 1103.0
HKD1_k127_4303536_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.321e-266 823.0
HKD1_k127_4303536_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
HKD1_k127_4303536_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
HKD1_k127_4303536_12 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 285.0
HKD1_k127_4303536_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005075 264.0
HKD1_k127_4303536_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006069 258.0
HKD1_k127_4303536_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004835 247.0
HKD1_k127_4303536_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000003966 234.0
HKD1_k127_4303536_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000294 221.0
HKD1_k127_4303536_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000008161 221.0
HKD1_k127_4303536_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000025 209.0
HKD1_k127_4303536_2 Cytochrome P450 - - - 2.504e-221 693.0
HKD1_k127_4303536_20 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000000000003277 199.0
HKD1_k127_4303536_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000000001255 185.0
HKD1_k127_4303536_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000001198 160.0
HKD1_k127_4303536_23 acetyltransferase K06966 - 3.2.2.10 0.000000000000000000000000000000000000004011 151.0
HKD1_k127_4303536_24 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002979 111.0
HKD1_k127_4303536_25 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000004993 108.0
HKD1_k127_4303536_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 8.153e-214 665.0
HKD1_k127_4303536_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 467.0
HKD1_k127_4303536_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 444.0
HKD1_k127_4303536_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 394.0
HKD1_k127_4303536_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 359.0
HKD1_k127_4303536_8 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 343.0
HKD1_k127_4303536_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
HKD1_k127_4346991_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1268.0
HKD1_k127_4346991_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 8.61e-225 700.0
HKD1_k127_4346991_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 593.0
HKD1_k127_4346991_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 541.0
HKD1_k127_4346991_4 YHYH protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008655 278.0
HKD1_k127_4346991_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000005038 139.0
HKD1_k127_435937_0 lactate metabolic process - - - 4.464e-215 674.0
HKD1_k127_435937_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 565.0
HKD1_k127_435937_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 564.0
HKD1_k127_435937_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003006 276.0
HKD1_k127_435937_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
HKD1_k127_435937_5 NIPSNAP - - - 0.000000000000000000000000000000000000000000005018 165.0
HKD1_k127_4434014_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1628.0
HKD1_k127_4434014_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 300.0
HKD1_k127_4434014_2 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 303.0
HKD1_k127_4434014_3 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
HKD1_k127_4434014_4 phosphatase activity K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
HKD1_k127_4434014_5 ABC-2 type transporter K09690 - - 0.0000000000000000000000000001972 117.0
HKD1_k127_4434014_6 Asp Glu hydantoin racemase - - - 0.00000000000000519 84.0
HKD1_k127_4443462_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 1.162e-220 699.0
HKD1_k127_4443462_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.369e-220 704.0
HKD1_k127_4443462_10 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000004085 158.0
HKD1_k127_4443462_11 - - - - 0.0000000000000000000000001114 117.0
HKD1_k127_4443462_12 SnoaL-like domain - - - 0.00000000000000000001278 98.0
HKD1_k127_4443462_13 - - - - 0.000000000008959 68.0
HKD1_k127_4443462_2 P-aminobenzoate N-oxygenase AurF - - - 2.487e-208 650.0
HKD1_k127_4443462_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 473.0
HKD1_k127_4443462_4 RibD C-terminal domain K00082 - 1.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 349.0
HKD1_k127_4443462_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 276.0
HKD1_k127_4443462_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
HKD1_k127_4443462_7 DoxX-like family K15977 - - 0.00000000000000000000000000000000000000000000000001002 188.0
HKD1_k127_4443462_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001555 173.0
HKD1_k127_4443462_9 - - - - 0.000000000000000000000000000000000000000003909 165.0
HKD1_k127_4450910_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0 1238.0
HKD1_k127_4450910_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 533.0
HKD1_k127_4450910_2 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 527.0
HKD1_k127_4450910_3 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 524.0
HKD1_k127_4450910_4 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 528.0
HKD1_k127_4450910_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 460.0
HKD1_k127_4450910_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 452.0
HKD1_k127_4450910_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 340.0
HKD1_k127_4450910_9 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.000000000000000001357 88.0
HKD1_k127_4461478_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1131.0
HKD1_k127_4461478_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1080.0
HKD1_k127_4461478_10 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 9.901e-220 685.0
HKD1_k127_4461478_11 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 587.0
HKD1_k127_4461478_12 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 581.0
HKD1_k127_4461478_13 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 542.0
HKD1_k127_4461478_14 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 514.0
HKD1_k127_4461478_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 517.0
HKD1_k127_4461478_16 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 466.0
HKD1_k127_4461478_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 467.0
HKD1_k127_4461478_18 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 452.0
HKD1_k127_4461478_19 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 403.0
HKD1_k127_4461478_2 Probable molybdopterin binding domain K07141 - 2.7.7.76 1.164e-296 929.0
HKD1_k127_4461478_20 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 382.0
HKD1_k127_4461478_21 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 375.0
HKD1_k127_4461478_22 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
HKD1_k127_4461478_23 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 355.0
HKD1_k127_4461478_24 Protein of unknown function (DUF1007) K00937,K06925 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
HKD1_k127_4461478_25 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 316.0
HKD1_k127_4461478_26 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 297.0
HKD1_k127_4461478_27 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
HKD1_k127_4461478_3 acetyl-coa acetyltransferase K00626 - 2.3.1.9 2.184e-291 900.0
HKD1_k127_4461478_30 Protein conserved in bacteria K09991 - - 0.00000000000000000000000000000000000000000000000000000000000000003203 229.0
HKD1_k127_4461478_31 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000005523 232.0
HKD1_k127_4461478_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000002171 226.0
HKD1_k127_4461478_33 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
HKD1_k127_4461478_34 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000000000000000000000000000006266 181.0
HKD1_k127_4461478_35 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000001911 191.0
HKD1_k127_4461478_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.273e-290 906.0
HKD1_k127_4461478_5 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.472e-269 835.0
HKD1_k127_4461478_6 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K21323 - 1.14.13.229,1.14.19.48 1.782e-241 766.0
HKD1_k127_4461478_7 VWA domain containing CoxE-like protein K07161 - - 1.562e-240 746.0
HKD1_k127_4461478_8 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 6.054e-239 747.0
HKD1_k127_4461478_9 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 2.14e-225 713.0
HKD1_k127_4470356_0 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 6.169e-239 750.0
HKD1_k127_4470356_1 Acyl-CoA dehydrogenase, middle domain - - - 7.621e-237 746.0
HKD1_k127_4470356_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 489.0
HKD1_k127_4470356_11 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 419.0
HKD1_k127_4470356_12 AAA ATPase K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 404.0
HKD1_k127_4470356_13 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 368.0
HKD1_k127_4470356_14 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 293.0
HKD1_k127_4470356_15 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
HKD1_k127_4470356_16 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
HKD1_k127_4470356_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000004142 232.0
HKD1_k127_4470356_18 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K21992 - - 0.0000000000000000000000000000000000000000000000000000000006647 211.0
HKD1_k127_4470356_19 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000001662 207.0
HKD1_k127_4470356_2 III protein, CoA-transferase family - - - 3.541e-220 696.0
HKD1_k127_4470356_20 COG3663 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000064 175.0
HKD1_k127_4470356_21 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000004673 166.0
HKD1_k127_4470356_22 PFAM thioesterase superfamily K18700 - 3.1.2.29 0.000000000000000000000000006602 113.0
HKD1_k127_4470356_23 - - - - 0.00000000000000000000008737 107.0
HKD1_k127_4470356_24 Cytochrome c - - - 0.0000000000000000000007188 99.0
HKD1_k127_4470356_25 - - - - 0.000000000000959 77.0
HKD1_k127_4470356_26 - - - - 0.00000003099 67.0
HKD1_k127_4470356_27 - - - - 0.0000002702 63.0
HKD1_k127_4470356_28 - - - - 0.000009908 55.0
HKD1_k127_4470356_3 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 5.206e-203 639.0
HKD1_k127_4470356_4 CoA-transferase family III - - - 5.829e-201 649.0
HKD1_k127_4470356_5 Protein of unknown function (DUF1254) - - - 2.386e-198 636.0
HKD1_k127_4470356_6 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 550.0
HKD1_k127_4470356_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 530.0
HKD1_k127_4470356_8 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 527.0
HKD1_k127_4470356_9 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 507.0
HKD1_k127_4474184_0 elongator protein 3 miab nifb - - - 0.0 1117.0
HKD1_k127_4474184_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 1.664e-229 713.0
HKD1_k127_4474184_10 Protein of unknown function (DUF3309) - - - 0.0000000000000000000001397 97.0
HKD1_k127_4474184_11 2Fe-2S -binding domain K02192 - - 0.000000000001562 70.0
HKD1_k127_4474184_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 3.573e-204 649.0
HKD1_k127_4474184_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 569.0
HKD1_k127_4474184_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 558.0
HKD1_k127_4474184_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 355.0
HKD1_k127_4474184_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 306.0
HKD1_k127_4474184_7 Belongs to the bacterioferritin family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 289.0
HKD1_k127_4474184_8 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 240.0
HKD1_k127_4474184_9 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002996 233.0
HKD1_k127_4491695_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 358.0
HKD1_k127_4491695_1 racemase activity, acting on amino acids and derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001235 279.0
HKD1_k127_4504909_0 secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 605.0
HKD1_k127_4504909_1 type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000006699 226.0
HKD1_k127_4504909_2 pilus assembly protein TadB K12510 - - 0.000000000000000000000000000000000000000000000002212 200.0
HKD1_k127_4504909_3 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.000000000000000000000000000000000000000002456 169.0
HKD1_k127_4524536_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.807e-271 842.0
HKD1_k127_4524536_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 408.0
HKD1_k127_4524536_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001221 236.0
HKD1_k127_4524536_3 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000001387 209.0
HKD1_k127_4524536_4 Helix-turn-helix K07334,K21498 - - 0.00000000000000000000000000000000000000000000001008 183.0
HKD1_k127_4524536_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000000000000009862 169.0
HKD1_k127_4524536_6 Serine aminopeptidase, S33 - - - 0.0001277 49.0
HKD1_k127_4524536_7 pathogenesis - - - 0.0003513 52.0
HKD1_k127_4563080_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1777.0
HKD1_k127_4563080_1 DEAD/H associated K03724 - - 0.0 1497.0
HKD1_k127_4563080_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 4.928e-203 633.0
HKD1_k127_4563080_11 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 567.0
HKD1_k127_4563080_12 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 586.0
HKD1_k127_4563080_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 522.0
HKD1_k127_4563080_14 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 497.0
HKD1_k127_4563080_15 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 485.0
HKD1_k127_4563080_16 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 485.0
HKD1_k127_4563080_17 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 432.0
HKD1_k127_4563080_18 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 426.0
HKD1_k127_4563080_19 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 396.0
HKD1_k127_4563080_2 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 5.141e-314 968.0
HKD1_k127_4563080_20 SOS response K14160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
HKD1_k127_4563080_21 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 359.0
HKD1_k127_4563080_23 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
HKD1_k127_4563080_24 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006425 269.0
HKD1_k127_4563080_25 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
HKD1_k127_4563080_26 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000003177 221.0
HKD1_k127_4563080_27 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000000008371 222.0
HKD1_k127_4563080_28 Transcriptional - - - 0.000000000000000000000000000000000000000000000003595 173.0
HKD1_k127_4563080_3 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.126e-311 970.0
HKD1_k127_4563080_30 Cytochrome c1 - - - 0.000000000000000000000000000000000000383 142.0
HKD1_k127_4563080_32 ABC transporter related K02049 - - 0.00000479 55.0
HKD1_k127_4563080_4 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 3.54e-283 880.0
HKD1_k127_4563080_5 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 1.09e-247 775.0
HKD1_k127_4563080_6 L-carnitine dehydratase bile acid-inducible protein F - - - 3.75e-221 690.0
HKD1_k127_4563080_7 Uncharacterized protein conserved in bacteria (DUF2252) - - - 2.907e-209 665.0
HKD1_k127_4563080_8 Mo-co oxidoreductase dimerisation domain - - - 6.985e-205 643.0
HKD1_k127_4563080_9 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 7.623e-205 639.0
HKD1_k127_4587264_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 1.469e-275 857.0
HKD1_k127_4587264_1 Peptidase family M20/M25/M40 - - - 1.079e-249 771.0
HKD1_k127_4587264_10 ChrR Cupin-like domain K07167 - - 0.00000000000000000000000000000003688 136.0
HKD1_k127_4587264_11 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000003091 117.0
HKD1_k127_4587264_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 486.0
HKD1_k127_4587264_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 479.0
HKD1_k127_4587264_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
HKD1_k127_4587264_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
HKD1_k127_4587264_6 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 315.0
HKD1_k127_4587264_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000004946 169.0
HKD1_k127_4587264_8 GYD domain - - - 0.0000000000000000000000000000000000000000008471 162.0
HKD1_k127_4587264_9 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000005008 146.0
HKD1_k127_4596065_0 transmembrane transport - - - 1.664e-206 649.0
HKD1_k127_4596065_1 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 459.0
HKD1_k127_4596065_10 Bacterial EndoU nuclease - - - 0.000000000000000156 88.0
HKD1_k127_4596065_11 Bacterial EndoU nuclease - - - 0.00000000000001927 82.0
HKD1_k127_4596065_12 Beta-lactamase - - - 0.000000000001547 74.0
HKD1_k127_4596065_13 Bacterial EndoU nuclease - - - 0.0000001207 61.0
HKD1_k127_4596065_2 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 455.0
HKD1_k127_4596065_3 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006079 274.0
HKD1_k127_4596065_4 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
HKD1_k127_4596065_5 - K20268 - - 0.00000000000000000000000000000000000000000000000005268 187.0
HKD1_k127_4596065_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000002087 161.0
HKD1_k127_4596065_7 Beta-lactamase - - - 0.0000000000000000000000000000000006291 142.0
HKD1_k127_4596065_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000001536 109.0
HKD1_k127_4596065_9 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000005576 85.0
HKD1_k127_4608416_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.803e-251 794.0
HKD1_k127_4608416_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 2.963e-231 719.0
HKD1_k127_4608416_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 407.0
HKD1_k127_4608416_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 291.0
HKD1_k127_4608416_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003355 262.0
HKD1_k127_4608416_5 Glycosyl Transferase - - - 0.0000000000000000001113 90.0
HKD1_k127_461319_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 520.0
HKD1_k127_461319_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 507.0
HKD1_k127_461319_2 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 358.0
HKD1_k127_461319_3 - - - - 0.00000000000000000000000000000000001424 139.0
HKD1_k127_4626668_0 DNA polymerase K02337 - 2.7.7.7 0.0 1930.0
HKD1_k127_4626668_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1266.0
HKD1_k127_4626668_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 512.0
HKD1_k127_4626668_11 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 487.0
HKD1_k127_4626668_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 441.0
HKD1_k127_4626668_13 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 426.0
HKD1_k127_4626668_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 422.0
HKD1_k127_4626668_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 417.0
HKD1_k127_4626668_16 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 374.0
HKD1_k127_4626668_17 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 350.0
HKD1_k127_4626668_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 320.0
HKD1_k127_4626668_19 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 286.0
HKD1_k127_4626668_2 Competence protein K02238 - - 0.0 1177.0
HKD1_k127_4626668_20 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 297.0
HKD1_k127_4626668_21 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000002572 196.0
HKD1_k127_4626668_22 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000981 167.0
HKD1_k127_4626668_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.679e-280 863.0
HKD1_k127_4626668_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.788e-266 826.0
HKD1_k127_4626668_5 zinc metalloprotease K11749 - - 2.596e-249 774.0
HKD1_k127_4626668_6 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 1.191e-218 684.0
HKD1_k127_4626668_7 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 8.882e-217 677.0
HKD1_k127_4626668_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 2.19e-199 634.0
HKD1_k127_4626668_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 567.0
HKD1_k127_4689867_0 L-carnitine dehydratase bile acid-inducible protein - - - 4.835e-209 655.0
HKD1_k127_4689867_1 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 515.0
HKD1_k127_4689867_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
HKD1_k127_4689867_3 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003546 264.0
HKD1_k127_4689867_4 - - - - 0.000000000000000000000000473 105.0
HKD1_k127_4693347_0 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 271.0
HKD1_k127_4693347_1 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000004886 161.0
HKD1_k127_4693347_3 - - - - 0.00001881 53.0
HKD1_k127_470925_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0 1089.0
HKD1_k127_470925_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.298e-319 991.0
HKD1_k127_470925_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001004 223.0
HKD1_k127_470925_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000002274 178.0
HKD1_k127_470925_12 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000238 171.0
HKD1_k127_470925_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000008658 168.0
HKD1_k127_470925_14 Acetyltransferase (GNAT) domain - - - 0.0000000005937 68.0
HKD1_k127_470925_15 acetyltransferase - - - 0.000103 53.0
HKD1_k127_470925_2 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 372.0
HKD1_k127_470925_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 368.0
HKD1_k127_470925_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 351.0
HKD1_k127_470925_5 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 308.0
HKD1_k127_470925_6 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 302.0
HKD1_k127_470925_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 252.0
HKD1_k127_470925_9 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001933 252.0
HKD1_k127_4710447_0 signal transduction histidine kinase K07636 - 2.7.13.3 3.257e-239 745.0
HKD1_k127_4710447_1 Radical SAM K06937 - - 2.489e-211 666.0
HKD1_k127_4710447_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
HKD1_k127_4710447_3 pathogenesis - - - 0.000000000000000000000000000001838 128.0
HKD1_k127_4710447_4 Autotransporter beta-domain - - - 0.00000000003233 65.0
HKD1_k127_4726480_0 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 1.954e-267 827.0
HKD1_k127_4726480_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
HKD1_k127_4726480_2 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 519.0
HKD1_k127_4726480_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 505.0
HKD1_k127_4726480_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 352.0
HKD1_k127_4726480_5 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 266.0
HKD1_k127_4726480_6 serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000005289 149.0
HKD1_k127_4757048_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0 1028.0
HKD1_k127_4757048_1 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 4.851e-266 835.0
HKD1_k127_4757048_10 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 380.0
HKD1_k127_4757048_11 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 380.0
HKD1_k127_4757048_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 360.0
HKD1_k127_4757048_13 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 355.0
HKD1_k127_4757048_14 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 348.0
HKD1_k127_4757048_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 347.0
HKD1_k127_4757048_16 ABC transporter K02065,K02068 GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
HKD1_k127_4757048_17 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 325.0
HKD1_k127_4757048_18 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 319.0
HKD1_k127_4757048_19 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
HKD1_k127_4757048_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 4.299e-259 811.0
HKD1_k127_4757048_20 AAA domain, putative AbiEii toxin, Type IV TA system K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 314.0
HKD1_k127_4757048_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
HKD1_k127_4757048_22 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 288.0
HKD1_k127_4757048_23 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003628 275.0
HKD1_k127_4757048_24 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
HKD1_k127_4757048_25 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000002708 276.0
HKD1_k127_4757048_26 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001112 247.0
HKD1_k127_4757048_27 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002717 238.0
HKD1_k127_4757048_28 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002089 223.0
HKD1_k127_4757048_29 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000002555 231.0
HKD1_k127_4757048_3 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01485 - 3.5.4.1 2.492e-196 619.0
HKD1_k127_4757048_30 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000006078 220.0
HKD1_k127_4757048_31 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
HKD1_k127_4757048_32 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000672 211.0
HKD1_k127_4757048_33 Globin - - - 0.000000000000000000000000000000000000000000000000165 183.0
HKD1_k127_4757048_34 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000007764 188.0
HKD1_k127_4757048_35 - - - - 0.0000000000000000000000000000000000000000000001248 173.0
HKD1_k127_4757048_36 Lipocalin-like domain - - - 0.00000000000000000000000000000008975 136.0
HKD1_k127_4757048_38 Endoribonuclease L-PSP - - - 0.00000000000000000000000007001 111.0
HKD1_k127_4757048_39 Peptidoglycan-binding domain 1 protein - - - 0.000000000000007242 85.0
HKD1_k127_4757048_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 556.0
HKD1_k127_4757048_40 - - - - 0.0000000271 60.0
HKD1_k127_4757048_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 522.0
HKD1_k127_4757048_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 462.0
HKD1_k127_4757048_7 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 456.0
HKD1_k127_4757048_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 456.0
HKD1_k127_4757048_9 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 401.0
HKD1_k127_4763926_0 Binding-protein-dependent transport system inner membrane component K02011 - - 5.306e-292 921.0
HKD1_k127_4763926_1 Flavin-binding monooxygenase-like - - - 2.503e-284 877.0
HKD1_k127_4763926_10 - - - - 0.000000000000000000000000000000000000000001095 158.0
HKD1_k127_4763926_11 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000009513 121.0
HKD1_k127_4763926_12 - - - - 0.000000000000000000000002585 104.0
HKD1_k127_4763926_13 Transposase DDE domain - - - 0.0000000000000001194 86.0
HKD1_k127_4763926_14 SnoaL-like polyketide cyclase K15945 - - 0.000000000003848 73.0
HKD1_k127_4763926_2 Bacterial extracellular solute-binding protein K02012 - - 3.099e-203 635.0
HKD1_k127_4763926_3 PrpF protein - - - 1.762e-202 636.0
HKD1_k127_4763926_4 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 600.0
HKD1_k127_4763926_5 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 511.0
HKD1_k127_4763926_6 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 289.0
HKD1_k127_4763926_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005864 260.0
HKD1_k127_4763926_8 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000452 253.0
HKD1_k127_4763926_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000006428 202.0
HKD1_k127_4764278_0 Class II Aldolase and Adducin N-terminal domain - - - 0.0 1154.0
HKD1_k127_4764278_1 PFAM amidohydrolase K07045 - - 3.51e-196 614.0
HKD1_k127_4764278_2 Aldo keto reductase K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 595.0
HKD1_k127_4764278_3 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
HKD1_k127_4764278_4 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 441.0
HKD1_k127_4764278_5 Membrane-associated sensor, integral membrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
HKD1_k127_4764278_6 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000000000000000000000000000005163 205.0
HKD1_k127_4773975_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1232.0
HKD1_k127_4773975_1 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0 1004.0
HKD1_k127_4773975_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.308e-205 643.0
HKD1_k127_4773975_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 585.0
HKD1_k127_4773975_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 556.0
HKD1_k127_4773975_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 511.0
HKD1_k127_4773975_14 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 478.0
HKD1_k127_4773975_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 469.0
HKD1_k127_4773975_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
HKD1_k127_4773975_17 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000001092 130.0
HKD1_k127_4773975_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0003855 43.0
HKD1_k127_4773975_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.94e-286 900.0
HKD1_k127_4773975_3 May be involved in recombinational repair of damaged DNA K03631 - - 1.826e-273 849.0
HKD1_k127_4773975_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 7.859e-257 796.0
HKD1_k127_4773975_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.279e-244 761.0
HKD1_k127_4773975_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 4.219e-241 754.0
HKD1_k127_4773975_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 3.247e-239 747.0
HKD1_k127_4773975_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.747e-219 694.0
HKD1_k127_4773975_9 Belongs to the SEDS family K03588 - - 5.532e-215 671.0
HKD1_k127_4785203_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.172e-283 876.0
HKD1_k127_4785203_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.017e-274 844.0
HKD1_k127_4785203_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 345.0
HKD1_k127_4785203_11 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 297.0
HKD1_k127_4785203_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 305.0
HKD1_k127_4785203_13 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009241 283.0
HKD1_k127_4785203_14 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004982 286.0
HKD1_k127_4785203_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005767 265.0
HKD1_k127_4785203_16 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
HKD1_k127_4785203_17 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
HKD1_k127_4785203_18 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005845 257.0
HKD1_k127_4785203_19 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000102 254.0
HKD1_k127_4785203_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 4.04e-219 685.0
HKD1_k127_4785203_20 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000002652 200.0
HKD1_k127_4785203_21 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000008202 150.0
HKD1_k127_4785203_22 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001665 130.0
HKD1_k127_4785203_24 Cupin 2, conserved barrel domain protein - - - 0.000000000000579 68.0
HKD1_k127_4785203_3 Cupin domain - - - 2.495e-213 665.0
HKD1_k127_4785203_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 584.0
HKD1_k127_4785203_5 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 572.0
HKD1_k127_4785203_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 519.0
HKD1_k127_4785203_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 482.0
HKD1_k127_4785203_8 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 422.0
HKD1_k127_4785203_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 357.0
HKD1_k127_479957_0 peptidylprolyl isomerase K03770 - 5.2.1.8 1.575e-309 960.0
HKD1_k127_479957_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 9.073e-295 916.0
HKD1_k127_479957_2 Glutathionylspermidine synthase preATP-grasp - - - 4.399e-238 741.0
HKD1_k127_479957_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.588e-198 631.0
HKD1_k127_479957_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 536.0
HKD1_k127_479957_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 451.0
HKD1_k127_479957_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 408.0
HKD1_k127_479957_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 316.0
HKD1_k127_479957_8 Domain of Unknown Function (DUF350) K08989 - - 0.00000000000000000000000000000000000000000000000000000000000000008954 224.0
HKD1_k127_479957_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000004758 177.0
HKD1_k127_4838078_0 acetyl-coa acetyltransferase - - - 4.668e-202 637.0
HKD1_k127_4838078_1 Uncharacterised MFS-type transporter YbfB - - - 9.104e-196 621.0
HKD1_k127_4838078_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
HKD1_k127_4838078_3 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
HKD1_k127_4838078_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004169 267.0
HKD1_k127_4838078_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007564 239.0
HKD1_k127_4838078_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000004329 222.0
HKD1_k127_4838078_7 Protein tyrosine kinase - - - 0.00000001314 63.0
HKD1_k127_4838078_8 CoA-transferase family III - - - 0.00003421 49.0
HKD1_k127_4849132_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 310.0
HKD1_k127_4849132_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
HKD1_k127_4849132_2 chaperone-mediated protein folding - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009627 273.0
HKD1_k127_4867642_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1347.0
HKD1_k127_4867642_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.462e-239 743.0
HKD1_k127_4867642_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002263 275.0
HKD1_k127_491087_0 Virulence factor SrfB - - - 0.0 1918.0
HKD1_k127_491087_1 Putative bacterial virulence factor - - - 2.68e-317 976.0
HKD1_k127_491087_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.688e-235 750.0
HKD1_k127_491087_3 Virulence effector protein - - - 1.32e-222 699.0
HKD1_k127_491087_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 440.0
HKD1_k127_491087_8 Hemin uptake protein - - - 0.000000001078 61.0
HKD1_k127_4914121_0 Adenylate cyclase - - - 1.057e-281 873.0
HKD1_k127_4914121_1 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000005811 60.0
HKD1_k127_491504_0 Protein export membrane protein - - - 0.0 1603.0
HKD1_k127_491504_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 3.229e-205 646.0
HKD1_k127_491504_2 ISXO2-like transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
HKD1_k127_491504_3 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
HKD1_k127_491504_4 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000002509 206.0
HKD1_k127_491504_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000003038 179.0
HKD1_k127_491504_6 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 - - 0.0000000000000000000000000003249 116.0
HKD1_k127_491504_7 Protein of unknown function (DUF2892) - - - 0.000000000000000000000005309 102.0
HKD1_k127_4933361_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 572.0
HKD1_k127_4933361_1 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 449.0
HKD1_k127_4933361_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000002111 193.0
HKD1_k127_494169_0 Alpha-2-Macroglobulin K06894 - - 0.0 2538.0
HKD1_k127_494169_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0 1097.0
HKD1_k127_494169_10 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001754 274.0
HKD1_k127_494169_11 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000003581 261.0
HKD1_k127_494169_12 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000002101 256.0
HKD1_k127_494169_2 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 4.438e-234 738.0
HKD1_k127_494169_3 flagellar motor protein K02557 - - 3.851e-204 640.0
HKD1_k127_494169_4 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 597.0
HKD1_k127_494169_5 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 557.0
HKD1_k127_494169_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 502.0
HKD1_k127_494169_7 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 481.0
HKD1_k127_494169_8 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
HKD1_k127_494169_9 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
HKD1_k127_4960134_0 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 392.0
HKD1_k127_4960134_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000004991 72.0
HKD1_k127_4967481_0 High confidence in function and specificity K07481 - - 1.177e-204 645.0
HKD1_k127_4967481_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 330.0
HKD1_k127_4967481_2 heavy metal translocating P-type ATPase - - - 0.000000005757 63.0
HKD1_k127_4968162_0 NUDIX domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
HKD1_k127_4968162_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 370.0
HKD1_k127_4968162_5 COG0457 FOG TPR repeat - - - 0.0000000000000000636 94.0
HKD1_k127_5024737_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 458.0
HKD1_k127_5024737_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 395.0
HKD1_k127_5024737_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000225 196.0
HKD1_k127_5024737_3 cytochrome P450 - - - 0.00000000000000000000000000000000000000001057 156.0
HKD1_k127_5026460_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1376.0
HKD1_k127_5026460_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1216.0
HKD1_k127_5026460_2 Domain of unknown function (DUF4139) - - - 3.656e-237 740.0
HKD1_k127_5026460_3 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002601 254.0
HKD1_k127_5026460_4 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000000000000005352 149.0
HKD1_k127_5026460_5 transcriptional regulator - - - 0.0000000000000000000866 97.0
HKD1_k127_503737_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.077e-249 773.0
HKD1_k127_503737_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 391.0
HKD1_k127_503737_4 transposase activity - - - 0.0000000000000000000000000000000001207 147.0
HKD1_k127_503737_5 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000004276 110.0
HKD1_k127_503737_6 Transcriptional regulator - - - 0.00000003239 54.0
HKD1_k127_5053006_0 Chain length determinant protein K16554 - - 0.0 1067.0
HKD1_k127_5053006_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 2.115e-237 742.0
HKD1_k127_5053006_10 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 564.0
HKD1_k127_5053006_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 561.0
HKD1_k127_5053006_12 transferase activity, transferring glycosyl groups K16558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 552.0
HKD1_k127_5053006_13 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 525.0
HKD1_k127_5053006_14 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 474.0
HKD1_k127_5053006_15 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 431.0
HKD1_k127_5053006_16 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 417.0
HKD1_k127_5053006_17 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
HKD1_k127_5053006_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 374.0
HKD1_k127_5053006_19 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 358.0
HKD1_k127_5053006_2 Amidohydrolase - - - 3.773e-234 727.0
HKD1_k127_5053006_20 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 337.0
HKD1_k127_5053006_21 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001884 277.0
HKD1_k127_5053006_22 HeAt shock protein - - - 0.000000000000000000000000000000000000000000000000000000000000002851 229.0
HKD1_k127_5053006_23 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000004498 219.0
HKD1_k127_5053006_26 Pectate lyase superfamily protein - - - 0.00000004502 66.0
HKD1_k127_5053006_27 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0003476 48.0
HKD1_k127_5053006_3 Bacterial extracellular solute-binding protein - - - 9.144e-234 729.0
HKD1_k127_5053006_4 Histidine kinase-like ATPases K14980 - 2.7.13.3 2.147e-220 696.0
HKD1_k127_5053006_5 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606,K20997 - - 1.372e-211 668.0
HKD1_k127_5053006_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 8.01e-207 656.0
HKD1_k127_5053006_7 Glycosyl transferase 4-like domain K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 608.0
HKD1_k127_5053006_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 604.0
HKD1_k127_5053006_9 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 592.0
HKD1_k127_5055752_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1092.0
HKD1_k127_5055752_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 7.625e-281 869.0
HKD1_k127_5055752_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 411.0
HKD1_k127_5055752_11 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 338.0
HKD1_k127_5055752_12 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 310.0
HKD1_k127_5055752_13 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000001232 250.0
HKD1_k127_5055752_14 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001674 245.0
HKD1_k127_5055752_15 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000389 218.0
HKD1_k127_5055752_16 - - - - 0.000000000000000000000000000000000000000000005477 168.0
HKD1_k127_5055752_17 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000006832 105.0
HKD1_k127_5055752_18 Transposase DDE domain - - - 0.00000000002503 63.0
HKD1_k127_5055752_2 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 9.583e-277 856.0
HKD1_k127_5055752_3 Luciferase-like monooxygenase - - - 4.883e-217 702.0
HKD1_k127_5055752_4 COG0477 Permeases of the major facilitator superfamily - - - 8.671e-214 669.0
HKD1_k127_5055752_5 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 583.0
HKD1_k127_5055752_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 557.0
HKD1_k127_5055752_7 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
HKD1_k127_5055752_8 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 498.0
HKD1_k127_5055752_9 Domain of unknown function (DUF1849) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 440.0
HKD1_k127_5077367_0 ABC-type dipeptide transport system periplasmic component K02035 - - 7.197e-228 717.0
HKD1_k127_5077367_1 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 504.0
HKD1_k127_5077367_2 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 332.0
HKD1_k127_5077367_3 Uracil-DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001323 278.0
HKD1_k127_5089014_0 Proton-conducting membrane transporter - - - 5.957e-301 936.0
HKD1_k127_5089014_1 Proton-conducting membrane transporter K12141 - - 9.737e-197 619.0
HKD1_k127_5089014_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 576.0
HKD1_k127_5089014_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 449.0
HKD1_k127_5089014_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 368.0
HKD1_k127_5089014_5 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 327.0
HKD1_k127_5089014_6 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 321.0
HKD1_k127_5089014_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004534 247.0
HKD1_k127_5089014_8 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000003551 211.0
HKD1_k127_5106_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 0.0 1698.0
HKD1_k127_5106_1 Flavoprotein involved in K transport K03379,K21730 - 1.14.13.160,1.14.13.22 2.434e-239 754.0
HKD1_k127_5106_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 331.0
HKD1_k127_5106_11 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 325.0
HKD1_k127_5106_12 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 321.0
HKD1_k127_5106_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
HKD1_k127_5106_14 Precorrin-6x reductase CbiJ/CobK K05895 - 1.3.1.106,1.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 265.0
HKD1_k127_5106_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
HKD1_k127_5106_16 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000009708 123.0
HKD1_k127_5106_17 cobalamin biosynthesis protein K02189 - 3.7.1.12 0.000000000000000000000000859 120.0
HKD1_k127_5106_2 Precorrin-6Y C5,15-methyltransferase K00595 - 2.1.1.132 1.052e-195 617.0
HKD1_k127_5106_20 carbohydrate kinase activity - - - 0.0000000000000000006881 100.0
HKD1_k127_5106_21 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000007879 72.0
HKD1_k127_5106_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 603.0
HKD1_k127_5106_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HKD1_k127_5106_5 Precorrin-4 K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
HKD1_k127_5106_6 Precorrin-2 K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 437.0
HKD1_k127_5106_7 Nitrite/Sulfite reductase ferredoxin-like half domain K02229 - 1.14.13.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 397.0
HKD1_k127_5106_8 Nitroreductase family K04719 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 394.0
HKD1_k127_5106_9 Precorrin-3B K05934,K13541 - 2.1.1.131,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 376.0
HKD1_k127_5117986_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.428e-274 850.0
HKD1_k127_5117986_1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 9.077e-214 670.0
HKD1_k127_5117986_10 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003822 268.0
HKD1_k127_5117986_11 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000001644 161.0
HKD1_k127_5117986_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000001218 148.0
HKD1_k127_5117986_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000003335 148.0
HKD1_k127_5117986_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 1.786e-204 643.0
HKD1_k127_5117986_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 593.0
HKD1_k127_5117986_4 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 484.0
HKD1_k127_5117986_5 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 462.0
HKD1_k127_5117986_6 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
HKD1_k127_5117986_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 432.0
HKD1_k127_5117986_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 349.0
HKD1_k127_5117986_9 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 320.0
HKD1_k127_5144042_0 Amidase - - - 1.361e-280 867.0
HKD1_k127_5144042_1 acetyl-coa acetyltransferase - - - 6.267e-230 715.0
HKD1_k127_5144042_10 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
HKD1_k127_5144042_11 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 319.0
HKD1_k127_5144042_12 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 303.0
HKD1_k127_5144042_13 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
HKD1_k127_5144042_14 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 272.0
HKD1_k127_5144042_15 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000007342 224.0
HKD1_k127_5144042_16 membrane K08988 - - 0.0000000000000000000000000000000000000000000000000000108 206.0
HKD1_k127_5144042_17 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000007978 169.0
HKD1_k127_5144042_18 Cytochrome c2 K08738 - - 0.0000000000000000000000001093 115.0
HKD1_k127_5144042_2 L-carnitine dehydratase bile acid-inducible protein F - - - 1.774e-228 711.0
HKD1_k127_5144042_22 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000001116 70.0
HKD1_k127_5144042_3 Major Facilitator Superfamily - - - 3.754e-206 646.0
HKD1_k127_5144042_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 590.0
HKD1_k127_5144042_5 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 580.0
HKD1_k127_5144042_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 520.0
HKD1_k127_5144042_7 Ribosomal protein L11 methyltransferase (PrmA) K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 465.0
HKD1_k127_5144042_8 Voltage-dependent anion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 438.0
HKD1_k127_5144042_9 COG1176 ABC-type spermidine putrescine transport system permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 332.0
HKD1_k127_5147553_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1228.0
HKD1_k127_5147553_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.55e-314 1000.0
HKD1_k127_5147553_10 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 535.0
HKD1_k127_5147553_11 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 533.0
HKD1_k127_5147553_12 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 524.0
HKD1_k127_5147553_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 455.0
HKD1_k127_5147553_14 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 433.0
HKD1_k127_5147553_15 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 429.0
HKD1_k127_5147553_16 transcriptional regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 411.0
HKD1_k127_5147553_17 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
HKD1_k127_5147553_18 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 363.0
HKD1_k127_5147553_19 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 329.0
HKD1_k127_5147553_2 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 2.548e-312 969.0
HKD1_k127_5147553_20 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
HKD1_k127_5147553_21 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002781 272.0
HKD1_k127_5147553_22 ABC-type Mn2 Zn2 transport systems, permease components K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
HKD1_k127_5147553_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
HKD1_k127_5147553_24 ATPases associated with a variety of cellular activities K02074 - - 0.000000000000000000000000000000000000000000000000000000000000000000002872 246.0
HKD1_k127_5147553_25 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003565 238.0
HKD1_k127_5147553_26 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000002938 196.0
HKD1_k127_5147553_28 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000009934 169.0
HKD1_k127_5147553_29 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000004345 141.0
HKD1_k127_5147553_3 TonB dependent receptor - - - 1.378e-280 882.0
HKD1_k127_5147553_30 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000003571 118.0
HKD1_k127_5147553_31 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001143 99.0
HKD1_k127_5147553_32 - - - - 0.000003459 59.0
HKD1_k127_5147553_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.182e-275 852.0
HKD1_k127_5147553_5 Phosphoesterase family K01114 - 3.1.4.3 2.892e-194 620.0
HKD1_k127_5147553_6 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 590.0
HKD1_k127_5147553_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 572.0
HKD1_k127_5147553_8 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 530.0
HKD1_k127_5147553_9 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 516.0
HKD1_k127_5157452_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1455.0
HKD1_k127_5157452_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 3.488e-207 653.0
HKD1_k127_5157452_2 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001046 276.0
HKD1_k127_5157452_3 Class ii aldolase K01628,K03077 - 4.1.2.17,5.1.3.4 0.00000000000000000000000000000000000000000000000000000000001993 216.0
HKD1_k127_5157452_4 - - - - 0.000000000000000000000000001538 124.0
HKD1_k127_5171122_0 Histidine kinase K07646 - 2.7.13.3 0.0 1367.0
HKD1_k127_5171122_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.784e-292 904.0
HKD1_k127_5171122_10 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 302.0
HKD1_k127_5171122_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 259.0
HKD1_k127_5171122_12 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000005913 235.0
HKD1_k127_5171122_13 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000002343 240.0
HKD1_k127_5171122_14 Metal-sensitive transcriptional repressor - - - 0.0000000000000000000000000000000000000000000832 164.0
HKD1_k127_5171122_16 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000001384 130.0
HKD1_k127_5171122_17 LTXXQ motif family protein - - - 0.0000000000000000000000000001075 123.0
HKD1_k127_5171122_18 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000001238 123.0
HKD1_k127_5171122_2 Multicopper oxidase - - - 4.175e-241 767.0
HKD1_k127_5171122_20 - - - - 0.0000000000000000000000004829 116.0
HKD1_k127_5171122_22 Protein of unknown function (DUF2933) - - - 0.000000000000000003056 86.0
HKD1_k127_5171122_23 Copper binding periplasmic protein CusF - - - 0.000000000000000003616 95.0
HKD1_k127_5171122_3 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
HKD1_k127_5171122_4 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 548.0
HKD1_k127_5171122_5 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 541.0
HKD1_k127_5171122_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 432.0
HKD1_k127_5171122_7 Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 394.0
HKD1_k127_5171122_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 383.0
HKD1_k127_5171122_9 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 376.0
HKD1_k127_5220192_0 membrane protein involved in D-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 331.0
HKD1_k127_5220192_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 329.0
HKD1_k127_5220192_10 - - - - 0.00000004017 65.0
HKD1_k127_5220192_2 Family of unknown function (DUF5309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003139 240.0
HKD1_k127_5220192_3 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000001457 179.0
HKD1_k127_5220192_4 tail collar domain protein - - - 0.000000000000000000000000000000000000001128 169.0
HKD1_k127_5220192_5 Phage Tail Collar Domain - - - 0.0000000000000000000000000001008 127.0
HKD1_k127_5220192_6 - - - - 0.0000000000000000000001261 102.0
HKD1_k127_5220192_7 - - - - 0.00000000000000001402 97.0
HKD1_k127_5220192_9 - - - - 0.00000002884 64.0
HKD1_k127_5232081_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.589e-312 960.0
HKD1_k127_5232081_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.685e-270 834.0
HKD1_k127_5232081_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000001676 169.0
HKD1_k127_5232081_11 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000003275 156.0
HKD1_k127_5232081_12 Methyltransferase domain - - - 0.00000000000000000000000000001004 136.0
HKD1_k127_5232081_14 - - - - 0.00000000000001396 79.0
HKD1_k127_5232081_15 Cupin domain - - - 0.0001427 48.0
HKD1_k127_5232081_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 4.281e-235 734.0
HKD1_k127_5232081_3 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 3.433e-212 663.0
HKD1_k127_5232081_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 7.104e-208 654.0
HKD1_k127_5232081_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 582.0
HKD1_k127_5232081_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 524.0
HKD1_k127_5232081_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 524.0
HKD1_k127_5232081_8 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 435.0
HKD1_k127_5232081_9 Glycosyltransferase like family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HKD1_k127_5248806_0 Major Facilitator Superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 451.0
HKD1_k127_5248806_1 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 364.0
HKD1_k127_5248806_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
HKD1_k127_5248806_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000003067 175.0
HKD1_k127_5248806_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000005515 181.0
HKD1_k127_5248806_5 Redoxin - - - 0.00000000000000000000000000000000001364 146.0
HKD1_k127_5248806_6 Patatin-like phospholipase K07001 - - 0.000000000000000002344 91.0
HKD1_k127_5254780_0 polysaccharide biosynthetic process - - - 4.665e-286 884.0
HKD1_k127_5254780_1 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 602.0
HKD1_k127_5254780_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000005197 199.0
HKD1_k127_5254780_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 550.0
HKD1_k127_5254780_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 537.0
HKD1_k127_5254780_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 492.0
HKD1_k127_5254780_5 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 485.0
HKD1_k127_5254780_6 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 287.0
HKD1_k127_5254780_7 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002089 249.0
HKD1_k127_5254780_8 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007103 239.0
HKD1_k127_5254780_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006841 236.0
HKD1_k127_5262908_0 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.0 1099.0
HKD1_k127_5262908_1 Rod shape-determining protein MreB K03569 - - 5.332e-210 654.0
HKD1_k127_5262908_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 2.786e-208 652.0
HKD1_k127_5262908_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 456.0
HKD1_k127_5262908_5 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 326.0
HKD1_k127_5269451_0 Dehydratase family K22186 - 4.2.1.82 0.0 1104.0
HKD1_k127_5269451_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K16090 - - 1.217e-307 960.0
HKD1_k127_5269451_10 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 544.0
HKD1_k127_5269451_11 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 527.0
HKD1_k127_5269451_12 Chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 539.0
HKD1_k127_5269451_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 510.0
HKD1_k127_5269451_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 493.0
HKD1_k127_5269451_15 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 449.0
HKD1_k127_5269451_16 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 429.0
HKD1_k127_5269451_17 carbohydrate binding K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 424.0
HKD1_k127_5269451_18 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 419.0
HKD1_k127_5269451_19 Hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 369.0
HKD1_k127_5269451_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.726e-291 914.0
HKD1_k127_5269451_20 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 359.0
HKD1_k127_5269451_21 PFAM PepSY-associated TM helix domain protein K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 354.0
HKD1_k127_5269451_22 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 340.0
HKD1_k127_5269451_23 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 307.0
HKD1_k127_5269451_24 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 309.0
HKD1_k127_5269451_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 293.0
HKD1_k127_5269451_26 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 289.0
HKD1_k127_5269451_27 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001113 282.0
HKD1_k127_5269451_28 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 272.0
HKD1_k127_5269451_29 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002741 273.0
HKD1_k127_5269451_3 transport system fused permease components - - - 1.455e-256 810.0
HKD1_k127_5269451_30 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
HKD1_k127_5269451_31 Protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005927 246.0
HKD1_k127_5269451_32 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000000000009811 245.0
HKD1_k127_5269451_34 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000000001007 230.0
HKD1_k127_5269451_35 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002765 218.0
HKD1_k127_5269451_36 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
HKD1_k127_5269451_37 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000003289 206.0
HKD1_k127_5269451_38 Cold shock protein domain - - - 0.00000000000000000000000000000000000000000000000000000002051 201.0
HKD1_k127_5269451_4 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 6.463e-246 767.0
HKD1_k127_5269451_40 - - - - 0.0000000000000000000000000000000000000000000000000002147 193.0
HKD1_k127_5269451_41 ETC complex I subunit conserved region - - - 0.000000000000000000000000000000000000000000000000002624 184.0
HKD1_k127_5269451_42 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000004839 190.0
HKD1_k127_5269451_43 transcriptional regulator - - - 0.00000000000000000000000000000000000000000002417 168.0
HKD1_k127_5269451_44 Ketosteroid isomerase-related protein - - - 0.000000000000000000000000003224 119.0
HKD1_k127_5269451_45 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000006404 112.0
HKD1_k127_5269451_46 membrane K08985 - - 0.00000000000000000000001797 100.0
HKD1_k127_5269451_5 Reductase C-terminal K05297 - 1.18.1.1 9.36e-241 754.0
HKD1_k127_5269451_6 Rieske 2Fe-2S - - - 5.661e-202 633.0
HKD1_k127_5269451_7 Major Facilitator Superfamily - - - 2.226e-198 623.0
HKD1_k127_5269451_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 550.0
HKD1_k127_5269451_9 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 551.0
HKD1_k127_5282325_0 protein involved in outer membrane biogenesis - - - 0.0 1215.0
HKD1_k127_5282325_1 His Kinase A (phosphoacceptor) domain - - - 0.0 1092.0
HKD1_k127_5282325_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.414e-247 773.0
HKD1_k127_5282325_3 mandelate racemase muconate lactonizing - - - 3.147e-208 651.0
HKD1_k127_5282325_4 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 379.0
HKD1_k127_5282325_5 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 363.0
HKD1_k127_5282528_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 5.108e-308 946.0
HKD1_k127_5282528_1 TonB-dependent receptor K16092 - - 8.157e-301 936.0
HKD1_k127_5282528_10 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 497.0
HKD1_k127_5282528_11 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 442.0
HKD1_k127_5282528_12 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 406.0
HKD1_k127_5282528_13 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 304.0
HKD1_k127_5282528_14 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
HKD1_k127_5282528_15 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000001764 223.0
HKD1_k127_5282528_16 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000000000000000000001246 189.0
HKD1_k127_5282528_17 Fe-S protein - - - 0.0000000000000000000000000000000000003359 149.0
HKD1_k127_5282528_18 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000004506 134.0
HKD1_k127_5282528_19 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000009893 78.0
HKD1_k127_5282528_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 8.011e-264 816.0
HKD1_k127_5282528_3 Cysteine-rich domain K11473 - - 1.241e-251 783.0
HKD1_k127_5282528_4 Amidohydrolase family - - - 3.102e-239 744.0
HKD1_k127_5282528_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.095e-235 747.0
HKD1_k127_5282528_6 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 8.14e-227 710.0
HKD1_k127_5282528_7 Putative sugar-binding N-terminal domain - - - 5.102e-225 704.0
HKD1_k127_5282528_8 FAD binding domain K11472 - - 8.689e-205 641.0
HKD1_k127_5282528_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 500.0
HKD1_k127_5284649_0 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.0 1037.0
HKD1_k127_5284649_1 COG1042 Acyl-CoA synthetase (NDP forming) - - - 1.356e-265 824.0
HKD1_k127_5284649_10 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 466.0
HKD1_k127_5284649_11 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 458.0
HKD1_k127_5284649_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 451.0
HKD1_k127_5284649_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 470.0
HKD1_k127_5284649_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 431.0
HKD1_k127_5284649_15 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 413.0
HKD1_k127_5284649_16 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 397.0
HKD1_k127_5284649_17 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 402.0
HKD1_k127_5284649_18 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 369.0
HKD1_k127_5284649_19 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 372.0
HKD1_k127_5284649_2 Psort location Cytoplasmic, score 7.50 - - - 5.954e-223 695.0
HKD1_k127_5284649_20 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 370.0
HKD1_k127_5284649_21 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 337.0
HKD1_k127_5284649_22 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
HKD1_k127_5284649_23 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 279.0
HKD1_k127_5284649_24 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
HKD1_k127_5284649_25 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001927 242.0
HKD1_k127_5284649_26 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000001478 216.0
HKD1_k127_5284649_27 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000573 124.0
HKD1_k127_5284649_29 Protein of unknown function (DUF4242) - - - 0.00000000000005549 77.0
HKD1_k127_5284649_3 Amidohydrolase family - - - 1.309e-199 627.0
HKD1_k127_5284649_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 603.0
HKD1_k127_5284649_5 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 590.0
HKD1_k127_5284649_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 581.0
HKD1_k127_5284649_7 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 556.0
HKD1_k127_5284649_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 537.0
HKD1_k127_5284649_9 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 481.0
HKD1_k127_5292141_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 4.093e-237 744.0
HKD1_k127_5292141_1 FAD dependent oxidoreductase - - - 1.092e-228 714.0
HKD1_k127_5292141_10 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 332.0
HKD1_k127_5292141_11 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
HKD1_k127_5292141_12 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 325.0
HKD1_k127_5292141_13 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 291.0
HKD1_k127_5292141_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002226 289.0
HKD1_k127_5292141_15 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000143 271.0
HKD1_k127_5292141_16 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000001569 174.0
HKD1_k127_5292141_17 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000004082 99.0
HKD1_k127_5292141_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.73e-216 687.0
HKD1_k127_5292141_3 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 541.0
HKD1_k127_5292141_4 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 548.0
HKD1_k127_5292141_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 539.0
HKD1_k127_5292141_6 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 465.0
HKD1_k127_5292141_7 Belongs to the enoyl-CoA hydratase isomerase family K08299,K16426 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 401.0
HKD1_k127_5292141_8 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 394.0
HKD1_k127_5292141_9 cyclic nucleotide binding K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 395.0
HKD1_k127_5302093_0 Biotin carboxylase C-terminal domain - - - 0.0 1854.0
HKD1_k127_5302093_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1225.0
HKD1_k127_5302093_10 COG0655 Multimeric flavodoxin WrbA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 288.0
HKD1_k127_5302093_11 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006117 271.0
HKD1_k127_5302093_12 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000003799 220.0
HKD1_k127_5302093_13 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000000000000000000000000000955 207.0
HKD1_k127_5302093_14 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000003473 93.0
HKD1_k127_5302093_15 mRNA binding K07339 - - 0.00000000002432 68.0
HKD1_k127_5302093_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.418e-273 844.0
HKD1_k127_5302093_3 Acyl-CoA dehydrogenase, middle domain - - - 2.956e-254 785.0
HKD1_k127_5302093_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.046e-217 678.0
HKD1_k127_5302093_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 561.0
HKD1_k127_5302093_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 507.0
HKD1_k127_5302093_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 467.0
HKD1_k127_5302093_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 460.0
HKD1_k127_5302093_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 391.0
HKD1_k127_5314249_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 0.0 1373.0
HKD1_k127_5314249_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.077e-317 976.0
HKD1_k127_5314249_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 434.0
HKD1_k127_5314249_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 424.0
HKD1_k127_5314249_12 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 393.0
HKD1_k127_5314249_13 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 390.0
HKD1_k127_5314249_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 340.0
HKD1_k127_5314249_15 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 307.0
HKD1_k127_5314249_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 278.0
HKD1_k127_5314249_17 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000877 252.0
HKD1_k127_5314249_18 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000005376 203.0
HKD1_k127_5314249_19 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000001643 208.0
HKD1_k127_5314249_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 7.595e-243 757.0
HKD1_k127_5314249_20 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002435 150.0
HKD1_k127_5314249_21 Acyltransferase family - - - 0.000000000000000000000000000000000008847 151.0
HKD1_k127_5314249_22 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000003264 117.0
HKD1_k127_5314249_23 Biotin-requiring enzyme - - - 0.000000000000007162 78.0
HKD1_k127_5314249_3 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 2.164e-195 614.0
HKD1_k127_5314249_4 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 545.0
HKD1_k127_5314249_5 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 538.0
HKD1_k127_5314249_6 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 535.0
HKD1_k127_5314249_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 538.0
HKD1_k127_5314249_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 520.0
HKD1_k127_5314249_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 492.0
HKD1_k127_5348466_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 330.0
HKD1_k127_5375529_0 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 3.653e-198 623.0
HKD1_k127_5375529_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000003284 118.0
HKD1_k127_5375529_2 (twin-arginine translocation) pathway signal - - - 0.000000000000000000003444 102.0
HKD1_k127_5375529_3 Protein of unknown function (DUF3365) - - - 0.00000000000000000002074 91.0
HKD1_k127_5400602_0 cytochrome P450 - - - 8.124e-211 657.0
HKD1_k127_5400602_1 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 557.0
HKD1_k127_5400602_2 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 318.0
HKD1_k127_5473111_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1139.0
HKD1_k127_5473111_1 Periplasmic binding protein K01999 - - 3.33e-218 684.0
HKD1_k127_5473111_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 497.0
HKD1_k127_5473111_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 493.0
HKD1_k127_5473111_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 440.0
HKD1_k127_5473111_5 Histidine kinase - - - 0.0000000000000002705 81.0
HKD1_k127_554087_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 9.9e-304 940.0
HKD1_k127_554087_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 335.0
HKD1_k127_554087_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
HKD1_k127_554087_3 - - - - 0.000000000000000000000000000000000000000000000000000000000002665 210.0
HKD1_k127_554503_0 ABC transporter K02471 - - 6.631e-269 837.0
HKD1_k127_554503_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.725e-218 690.0
HKD1_k127_554503_10 DHHA2 domain protein K15986 - 3.6.1.1 0.00005068 54.0
HKD1_k127_554503_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 548.0
HKD1_k127_554503_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 436.0
HKD1_k127_554503_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 397.0
HKD1_k127_554503_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 350.0
HKD1_k127_554503_6 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
HKD1_k127_554503_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007396 258.0
HKD1_k127_554503_8 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000006345 206.0
HKD1_k127_554503_9 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000000000000346 168.0
HKD1_k127_5577830_0 protein involved in outer membrane biogenesis - - - 0.0 1372.0
HKD1_k127_5577830_1 GTP-binding protein TypA K06207 - - 0.0 1054.0
HKD1_k127_5577830_10 Ribbon-helix-helix domain - - - 0.000000000000000000003607 95.0
HKD1_k127_5577830_11 Domain of unknown function (DUF4169) - - - 0.000000004724 69.0
HKD1_k127_5577830_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0 1036.0
HKD1_k127_5577830_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 596.0
HKD1_k127_5577830_4 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 513.0
HKD1_k127_5577830_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 465.0
HKD1_k127_5577830_6 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 433.0
HKD1_k127_5577830_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 418.0
HKD1_k127_5577830_8 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
HKD1_k127_5577830_9 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008031 275.0
HKD1_k127_5580046_0 ABC transporter transmembrane region - - - 0.0 1465.0
HKD1_k127_5580046_1 Phosphotransferase enzyme family - - - 3.879e-195 638.0
HKD1_k127_5580046_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 478.0
HKD1_k127_5580046_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 426.0
HKD1_k127_5580046_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 297.0
HKD1_k127_5580046_5 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000002577 235.0
HKD1_k127_5580046_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000001676 210.0
HKD1_k127_559210_0 Coenzyme A transferase K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 424.0
HKD1_k127_559210_1 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 396.0
HKD1_k127_559210_2 PFAM ABC transporter K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 316.0
HKD1_k127_559210_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 286.0
HKD1_k127_559210_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001714 104.0
HKD1_k127_559210_5 ABC transporter K02049,K15555 - - 0.0000000000000000003495 87.0
HKD1_k127_5601679_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0 1093.0
HKD1_k127_5601679_1 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 2.598e-225 700.0
HKD1_k127_5601679_10 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 415.0
HKD1_k127_5601679_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 336.0
HKD1_k127_5601679_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
HKD1_k127_5601679_13 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
HKD1_k127_5601679_14 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004193 293.0
HKD1_k127_5601679_16 Urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003237 177.0
HKD1_k127_5601679_17 - - - - 0.0000000000000000000000000002367 117.0
HKD1_k127_5601679_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 4.068e-208 649.0
HKD1_k127_5601679_3 HflC and HflK could encode or regulate a protease K04088 - - 9.822e-203 636.0
HKD1_k127_5601679_4 N-terminal domain of oxidoreductase K07119 - - 1.184e-194 614.0
HKD1_k127_5601679_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 589.0
HKD1_k127_5601679_6 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 507.0
HKD1_k127_5601679_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 503.0
HKD1_k127_5601679_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 474.0
HKD1_k127_5601679_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 471.0
HKD1_k127_5607628_0 AIR synthase related protein, C-terminal domain - - - 0.0 1127.0
HKD1_k127_5607628_1 oligosaccharyl transferase activity - - - 4.799e-197 626.0
HKD1_k127_5607628_2 Thioesterase - - - 0.00000000000000000000000000000000000000001341 153.0
HKD1_k127_5607628_3 OsmC-like protein K07397 - - 0.000000000008746 65.0
HKD1_k127_5629029_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1146.0
HKD1_k127_5629029_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.007e-296 915.0
HKD1_k127_5629029_10 ubiquitin protein ligase binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 402.0
HKD1_k127_5629029_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 362.0
HKD1_k127_5629029_12 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 347.0
HKD1_k127_5629029_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 346.0
HKD1_k127_5629029_14 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 297.0
HKD1_k127_5629029_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001815 230.0
HKD1_k127_5629029_16 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000005025 229.0
HKD1_k127_5629029_19 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000853 193.0
HKD1_k127_5629029_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.431e-228 714.0
HKD1_k127_5629029_20 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000001375 172.0
HKD1_k127_5629029_21 - - - - 0.0000000000000000000000000000000000000000001489 177.0
HKD1_k127_5629029_22 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000000000000000000001256 150.0
HKD1_k127_5629029_24 CsbD-like - - - 0.000000000000000000000000000001669 122.0
HKD1_k127_5629029_25 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000001618 120.0
HKD1_k127_5629029_26 Tetratricopeptide repeat - - - 0.000000000000000000000000157 116.0
HKD1_k127_5629029_27 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000002758 113.0
HKD1_k127_5629029_28 Protein of unknown function (DUF1328) - - - 0.0000000000000000001623 91.0
HKD1_k127_5629029_3 amidohydrolase - - - 2.897e-215 671.0
HKD1_k127_5629029_32 TadE-like protein - - - 0.00001073 53.0
HKD1_k127_5629029_33 PFAM TadE family protein - - - 0.000314 51.0
HKD1_k127_5629029_4 Histidine kinase - - - 3.311e-211 684.0
HKD1_k127_5629029_5 DinB superfamily - - - 6.895e-194 611.0
HKD1_k127_5629029_6 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 597.0
HKD1_k127_5629029_7 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 497.0
HKD1_k127_5629029_8 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 486.0
HKD1_k127_5629029_9 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 421.0
HKD1_k127_5640440_0 dioxygenase K11159 - - 3.936e-286 881.0
HKD1_k127_5640440_1 Beta-lactamase - - - 2.283e-218 697.0
HKD1_k127_5640440_10 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 332.0
HKD1_k127_5640440_11 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 332.0
HKD1_k127_5640440_12 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 333.0
HKD1_k127_5640440_13 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 304.0
HKD1_k127_5640440_14 bond formation protein, DsbB - - - 0.00000000000000000000000000000000000000000000000000000000000000004449 226.0
HKD1_k127_5640440_15 - - - - 0.00002049 55.0
HKD1_k127_5640440_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 1.314e-201 631.0
HKD1_k127_5640440_3 Nitronate monooxygenase K00459 - 1.13.12.16 5.584e-201 630.0
HKD1_k127_5640440_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 598.0
HKD1_k127_5640440_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 534.0
HKD1_k127_5640440_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 460.0
HKD1_k127_5640440_7 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 375.0
HKD1_k127_5640440_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 367.0
HKD1_k127_5640440_9 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 352.0
HKD1_k127_5664672_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1109.0
HKD1_k127_5664672_1 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 296.0
HKD1_k127_5689019_0 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.0 1111.0
HKD1_k127_5689019_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 3.666e-298 920.0
HKD1_k127_5689019_10 Transmembrane secretion effector - - - 9.167e-201 651.0
HKD1_k127_5689019_11 Carbon-nitrogen hydrolase - - - 1.53e-196 614.0
HKD1_k127_5689019_12 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 4.908e-195 620.0
HKD1_k127_5689019_13 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 561.0
HKD1_k127_5689019_14 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 523.0
HKD1_k127_5689019_15 GDP-mannose 4,6 dehydratase K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 487.0
HKD1_k127_5689019_16 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 483.0
HKD1_k127_5689019_17 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
HKD1_k127_5689019_18 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 419.0
HKD1_k127_5689019_19 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 398.0
HKD1_k127_5689019_2 Homospermidine synthase K00808 - 2.5.1.44 5.698e-270 835.0
HKD1_k127_5689019_20 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 353.0
HKD1_k127_5689019_21 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 361.0
HKD1_k127_5689019_22 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 307.0
HKD1_k127_5689019_23 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
HKD1_k127_5689019_24 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
HKD1_k127_5689019_25 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006353 269.0
HKD1_k127_5689019_26 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
HKD1_k127_5689019_27 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
HKD1_k127_5689019_28 Invasion associated locus B (IalB) protein - - - 0.0000000000000000000000000000000000000000000000009111 182.0
HKD1_k127_5689019_29 ChaB K06197 - - 0.00000000000000000000000199 105.0
HKD1_k127_5689019_3 Bacterial extracellular solute-binding protein K05813 - - 4.481e-255 790.0
HKD1_k127_5689019_30 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.000000000000002099 91.0
HKD1_k127_5689019_31 Transposase DDE domain - - - 0.00000000002503 63.0
HKD1_k127_5689019_4 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 1.02e-237 736.0
HKD1_k127_5689019_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.201e-237 749.0
HKD1_k127_5689019_6 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 5.606e-230 717.0
HKD1_k127_5689019_7 acetyltransferase - - - 1.341e-219 684.0
HKD1_k127_5689019_8 Autotransporter beta-domain - - - 6.557e-209 687.0
HKD1_k127_5689019_9 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816 - 3.6.3.20 9.27e-204 637.0
HKD1_k127_5737691_0 glutamate--cysteine ligase K01919 - 6.3.2.2 3.95e-279 862.0
HKD1_k127_5737691_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 530.0
HKD1_k127_5737691_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 502.0
HKD1_k127_5737691_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 502.0
HKD1_k127_5737691_4 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 485.0
HKD1_k127_5737691_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 419.0
HKD1_k127_5737691_6 Amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 393.0
HKD1_k127_5737691_7 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000001032 158.0
HKD1_k127_585354_0 amine dehydrogenase activity K03418 - 3.5.1.56 0.0 1281.0
HKD1_k127_585354_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 4.525e-260 809.0
HKD1_k127_585354_10 - - - - 0.0000000002002 62.0
HKD1_k127_585354_2 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 3.177e-204 639.0
HKD1_k127_585354_3 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 7.613e-198 637.0
HKD1_k127_585354_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
HKD1_k127_585354_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 400.0
HKD1_k127_585354_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 342.0
HKD1_k127_585354_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000006955 113.0
HKD1_k127_585354_8 - - - - 0.000000000000000000000682 96.0
HKD1_k127_585354_9 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.000000000001773 67.0
HKD1_k127_5964349_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 544.0
HKD1_k127_5964349_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 439.0
HKD1_k127_5964349_2 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 422.0
HKD1_k127_5964349_3 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 361.0
HKD1_k127_5964349_4 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 351.0
HKD1_k127_5977287_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.323e-197 628.0
HKD1_k127_5977287_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000003687 149.0
HKD1_k127_6022734_0 Adenylate cyclase K01768 - 4.6.1.1 1.522e-272 849.0
HKD1_k127_6022734_1 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 513.0
HKD1_k127_6022734_10 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000937 270.0
HKD1_k127_6022734_11 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000007771 226.0
HKD1_k127_6022734_12 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000002615 145.0
HKD1_k127_6022734_13 - - - - 0.0000000000000001641 83.0
HKD1_k127_6022734_14 - - - - 0.00004578 55.0
HKD1_k127_6022734_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 496.0
HKD1_k127_6022734_3 Capsular polysaccharide biosynthesis protein CapK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 407.0
HKD1_k127_6022734_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 357.0
HKD1_k127_6022734_5 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 342.0
HKD1_k127_6022734_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 340.0
HKD1_k127_6022734_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 313.0
HKD1_k127_6022734_8 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000143 282.0
HKD1_k127_6022734_9 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 282.0
HKD1_k127_6052373_0 monooxygenase - - - 2.776e-225 711.0
HKD1_k127_6052373_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.82e-211 675.0
HKD1_k127_6052373_10 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 327.0
HKD1_k127_6052373_11 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 247.0
HKD1_k127_6052373_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000004604 222.0
HKD1_k127_6052373_13 - - - - 0.000000000000000000000000000000000000000000000000000000000001503 218.0
HKD1_k127_6052373_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000002253 227.0
HKD1_k127_6052373_15 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000003569 172.0
HKD1_k127_6052373_16 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000004186 117.0
HKD1_k127_6052373_17 - - - - 0.000000000005925 70.0
HKD1_k127_6052373_18 Transposase IS116/IS110/IS902 family K07486 - - 0.00000001316 55.0
HKD1_k127_6052373_2 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 546.0
HKD1_k127_6052373_20 Ribonuclease H protein K20164 - - 0.0001078 54.0
HKD1_k127_6052373_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 462.0
HKD1_k127_6052373_4 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 424.0
HKD1_k127_6052373_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 422.0
HKD1_k127_6052373_6 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 403.0
HKD1_k127_6052373_7 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 344.0
HKD1_k127_6052373_8 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 331.0
HKD1_k127_6052373_9 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 334.0
HKD1_k127_6052810_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.442e-287 887.0
HKD1_k127_6052810_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 381.0
HKD1_k127_6052810_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 331.0
HKD1_k127_6052810_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007924 273.0
HKD1_k127_6074360_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 7.003e-318 979.0
HKD1_k127_6074360_1 Luciferase-like monooxygenase - - - 1.41e-249 773.0
HKD1_k127_6074360_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 434.0
HKD1_k127_6074360_11 belongs to the nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
HKD1_k127_6074360_12 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 420.0
HKD1_k127_6074360_13 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 398.0
HKD1_k127_6074360_14 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 341.0
HKD1_k127_6074360_15 formyl-CoA transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001681 289.0
HKD1_k127_6074360_16 Involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000000000000001085 186.0
HKD1_k127_6074360_17 formyl-CoA transferase activity - - - 0.0000000000000000000000000000000000000000000007921 181.0
HKD1_k127_6074360_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000003216 139.0
HKD1_k127_6074360_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000005189 91.0
HKD1_k127_6074360_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.339e-238 738.0
HKD1_k127_6074360_3 FAD binding domain - - - 2.057e-227 707.0
HKD1_k127_6074360_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 579.0
HKD1_k127_6074360_5 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 575.0
HKD1_k127_6074360_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 540.0
HKD1_k127_6074360_7 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 527.0
HKD1_k127_6074360_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 477.0
HKD1_k127_6074360_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 475.0
HKD1_k127_6104429_0 AMP-binding enzyme C-terminal domain - - - 2.364e-308 951.0
HKD1_k127_6104429_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.061e-304 942.0
HKD1_k127_6104429_10 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 589.0
HKD1_k127_6104429_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 586.0
HKD1_k127_6104429_12 ammonia monooxygenase K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 586.0
HKD1_k127_6104429_13 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 544.0
HKD1_k127_6104429_14 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 502.0
HKD1_k127_6104429_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 494.0
HKD1_k127_6104429_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 440.0
HKD1_k127_6104429_17 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 412.0
HKD1_k127_6104429_18 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
HKD1_k127_6104429_19 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 394.0
HKD1_k127_6104429_2 GTP cyclohydrolase II activity - - - 1.192e-260 805.0
HKD1_k127_6104429_20 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 382.0
HKD1_k127_6104429_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 374.0
HKD1_k127_6104429_22 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 389.0
HKD1_k127_6104429_23 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HKD1_k127_6104429_24 Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 292.0
HKD1_k127_6104429_25 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001448 255.0
HKD1_k127_6104429_26 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008746 248.0
HKD1_k127_6104429_27 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008325 238.0
HKD1_k127_6104429_28 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000004114 224.0
HKD1_k127_6104429_29 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
HKD1_k127_6104429_3 Luciferase-like monooxygenase - - - 1.538e-246 766.0
HKD1_k127_6104429_30 protein conserved in bacteria K09796 - - 0.00000000000000000000000000000000000000000000000000000000000006216 221.0
HKD1_k127_6104429_31 Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000001045 209.0
HKD1_k127_6104429_32 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000002947 196.0
HKD1_k127_6104429_33 Small multidrug resistance protein K11741 - - 0.0000000000000000000000000000000000000000000000000001381 192.0
HKD1_k127_6104429_34 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000002101 191.0
HKD1_k127_6104429_35 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000005563 173.0
HKD1_k127_6104429_38 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000002911 128.0
HKD1_k127_6104429_39 - - - - 0.00000000000000011 82.0
HKD1_k127_6104429_4 Transmembrane secretion effector - - - 9.819e-220 690.0
HKD1_k127_6104429_40 - - - - 0.0000000001035 67.0
HKD1_k127_6104429_41 - - - - 0.00000006023 55.0
HKD1_k127_6104429_42 - - - - 0.00003161 49.0
HKD1_k127_6104429_43 - - - - 0.00003435 52.0
HKD1_k127_6104429_5 Luciferase-like monooxygenase - - - 4.791e-213 663.0
HKD1_k127_6104429_6 FAD dependent oxidoreductase K19746 - 1.4.99.6 2.322e-198 625.0
HKD1_k127_6104429_7 Protein of unknown function (DUF1688) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 610.0
HKD1_k127_6104429_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 598.0
HKD1_k127_6104429_9 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 601.0
HKD1_k127_6113426_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0 1297.0
HKD1_k127_6113426_1 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.0 1030.0
HKD1_k127_6113426_10 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 297.0
HKD1_k127_6113426_11 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
HKD1_k127_6113426_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 281.0
HKD1_k127_6113426_13 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000003582 202.0
HKD1_k127_6113426_14 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001141 183.0
HKD1_k127_6113426_15 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000001103 160.0
HKD1_k127_6113426_16 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000006651 139.0
HKD1_k127_6113426_17 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000000001255 132.0
HKD1_k127_6113426_18 - - - - 0.00000000000000000000000000009454 117.0
HKD1_k127_6113426_2 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain - - - 3.205e-244 755.0
HKD1_k127_6113426_3 BFD-like [2Fe-2S] binding domain - - - 8.61e-242 754.0
HKD1_k127_6113426_4 Belongs to the thiolase family K00626 - 2.3.1.9 2.946e-234 729.0
HKD1_k127_6113426_5 FAD dependent oxidoreductase - - - 3.932e-219 682.0
HKD1_k127_6113426_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 550.0
HKD1_k127_6113426_7 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 531.0
HKD1_k127_6113426_8 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 516.0
HKD1_k127_6113426_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 456.0
HKD1_k127_6116448_0 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 4.104e-211 662.0
HKD1_k127_6116448_1 restriction endonuclease K07454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 494.0
HKD1_k127_6116448_2 protocatechuate 3,4-dioxygenase, beta subunit K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 418.0
HKD1_k127_6116448_3 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 307.0
HKD1_k127_6116448_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000114 115.0
HKD1_k127_6150625_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.231e-257 794.0
HKD1_k127_6150625_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000001815 207.0
HKD1_k127_6170033_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1505.0
HKD1_k127_6170033_1 Circularly permuted ATP-grasp type 2 - - - 0.0 1355.0
HKD1_k127_6170033_10 monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 556.0
HKD1_k127_6170033_11 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 507.0
HKD1_k127_6170033_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 442.0
HKD1_k127_6170033_13 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 440.0
HKD1_k127_6170033_14 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 436.0
HKD1_k127_6170033_15 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 432.0
HKD1_k127_6170033_16 Nitroreductase K10678 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 431.0
HKD1_k127_6170033_17 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 419.0
HKD1_k127_6170033_18 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 411.0
HKD1_k127_6170033_19 Methyladenine glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 396.0
HKD1_k127_6170033_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 2.579e-307 955.0
HKD1_k127_6170033_20 PFAM Asp Glu hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
HKD1_k127_6170033_21 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 366.0
HKD1_k127_6170033_22 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 319.0
HKD1_k127_6170033_23 NAD(FAD)-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
HKD1_k127_6170033_24 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001203 287.0
HKD1_k127_6170033_25 Acetyltransferase (GNAT) domain K03829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007553 256.0
HKD1_k127_6170033_26 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003851 263.0
HKD1_k127_6170033_27 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD1_k127_6170033_28 Ion channel - - - 0.0000000000000000000000000000000000002507 146.0
HKD1_k127_6170033_29 LTXXQ motif family protein - - - 0.0000000000000000113 90.0
HKD1_k127_6170033_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.236e-294 912.0
HKD1_k127_6170033_30 Amidohydrolase K07045 - - 0.0005362 51.0
HKD1_k127_6170033_4 Amidase K01426 - 3.5.1.4 4.194e-255 816.0
HKD1_k127_6170033_5 Alcohol dehydrogenase GroES-like domain - - - 5.049e-225 713.0
HKD1_k127_6170033_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.581e-204 665.0
HKD1_k127_6170033_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 2.404e-202 634.0
HKD1_k127_6170033_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 603.0
HKD1_k127_6170033_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 595.0
HKD1_k127_6184192_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
HKD1_k127_6184192_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
HKD1_k127_6184192_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000009514 199.0
HKD1_k127_6184192_3 PIN domain - - - 0.0000000000000000000000000185 117.0
HKD1_k127_6223051_0 RQC K03654 - 3.6.4.12 0.0 1002.0
HKD1_k127_6223051_1 amine dehydrogenase activity - - - 6.659e-313 964.0
HKD1_k127_6223051_10 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 334.0
HKD1_k127_6223051_11 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 329.0
HKD1_k127_6223051_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000001628 199.0
HKD1_k127_6223051_2 CoA-transferase family III K01796 - 5.1.99.4 1.45e-230 718.0
HKD1_k127_6223051_3 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 567.0
HKD1_k127_6223051_4 de-polymerase K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 499.0
HKD1_k127_6223051_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 482.0
HKD1_k127_6223051_6 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 481.0
HKD1_k127_6223051_7 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 383.0
HKD1_k127_6223051_8 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 355.0
HKD1_k127_6223051_9 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
HKD1_k127_6232395_0 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 1.133e-290 893.0
HKD1_k127_6232395_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 326.0
HKD1_k127_6232395_2 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004694 248.0
HKD1_k127_6232395_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000005472 149.0
HKD1_k127_6232395_4 PFAM Integrase catalytic region - - - 0.00000000000000000000492 93.0
HKD1_k127_6237611_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.87e-322 989.0
HKD1_k127_6237611_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.716e-318 975.0
HKD1_k127_6237611_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 539.0
HKD1_k127_6237611_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 521.0
HKD1_k127_6237611_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 393.0
HKD1_k127_6237611_6 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 357.0
HKD1_k127_6237611_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002713 254.0
HKD1_k127_6261926_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 6.379e-316 978.0
HKD1_k127_6261926_1 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K16319,K18074 - 1.14.12.1,1.14.12.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 483.0
HKD1_k127_6261926_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 362.0
HKD1_k127_6271900_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1039.0
HKD1_k127_6271900_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 8.851e-269 835.0
HKD1_k127_6271900_10 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002848 283.0
HKD1_k127_6271900_11 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005452 274.0
HKD1_k127_6271900_12 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
HKD1_k127_6271900_13 Protein involved in transporter activity and transport K12368 GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000008934 100.0
HKD1_k127_6271900_2 FAD dependent oxidoreductase - - - 2.261e-211 660.0
HKD1_k127_6271900_3 Rieske [2Fe-2S] domain - - - 1.513e-208 683.0
HKD1_k127_6271900_4 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 565.0
HKD1_k127_6271900_5 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 550.0
HKD1_k127_6271900_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 558.0
HKD1_k127_6271900_7 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
HKD1_k127_6271900_8 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 353.0
HKD1_k127_6271900_9 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
HKD1_k127_6283569_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1112.0
HKD1_k127_6283569_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.328e-227 706.0
HKD1_k127_6283569_10 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 369.0
HKD1_k127_6283569_11 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 327.0
HKD1_k127_6283569_12 transcriptional regulator, MerR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 313.0
HKD1_k127_6283569_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 304.0
HKD1_k127_6283569_14 Uncharacterized ACR, COG1399 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 272.0
HKD1_k127_6283569_15 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000004789 257.0
HKD1_k127_6283569_16 Ubiquinol-cytochrome C chaperone K17662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
HKD1_k127_6283569_17 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000755 267.0
HKD1_k127_6283569_18 COG2913 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HKD1_k127_6283569_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000008353 150.0
HKD1_k127_6283569_2 Major Facilitator Superfamily - - - 2.719e-215 675.0
HKD1_k127_6283569_20 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000003083 134.0
HKD1_k127_6283569_21 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000000000102 108.0
HKD1_k127_6283569_22 - - - - 0.000000000000000000000327 99.0
HKD1_k127_6283569_3 Major Facilitator Superfamily - - - 1.412e-203 663.0
HKD1_k127_6283569_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 605.0
HKD1_k127_6283569_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 593.0
HKD1_k127_6283569_6 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 582.0
HKD1_k127_6283569_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 533.0
HKD1_k127_6283569_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 480.0
HKD1_k127_6283569_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
HKD1_k127_6295762_0 Periplasmic binding protein - - - 3.272e-222 726.0
HKD1_k127_6295762_1 Belongs to the binding-protein-dependent transport system permease family - - - 2.811e-202 632.0
HKD1_k127_6295762_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 489.0
HKD1_k127_6295762_3 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 471.0
HKD1_k127_6313472_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1153.0
HKD1_k127_6313472_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1065.0
HKD1_k127_6313472_10 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 402.0
HKD1_k127_6313472_11 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
HKD1_k127_6313472_12 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 352.0
HKD1_k127_6313472_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 323.0
HKD1_k127_6313472_14 PFAM secretion protein HlyD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 314.0
HKD1_k127_6313472_15 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000000000000003155 201.0
HKD1_k127_6313472_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000005349 203.0
HKD1_k127_6313472_17 Lipopolysaccharide assembly protein A domain - - - 0.00000000000000000000000000000000000000000000000001413 188.0
HKD1_k127_6313472_18 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000000000000000000000000002518 170.0
HKD1_k127_6313472_19 - - - - 0.0000000000000000000000000000000000000000000004615 175.0
HKD1_k127_6313472_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0 1054.0
HKD1_k127_6313472_20 DNA-binding transcription factor activity K06075 - - 0.000000000000000000000000000000000000000000001024 170.0
HKD1_k127_6313472_21 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000391 105.0
HKD1_k127_6313472_22 - - - - 0.0000007273 59.0
HKD1_k127_6313472_3 COG1180 Pyruvate-formate lyase-activating enzyme - - - 1.709e-293 903.0
HKD1_k127_6313472_4 L-carnitine dehydratase bile acid-inducible protein - - - 1.667e-242 760.0
HKD1_k127_6313472_5 Receptor family ligand binding region K01999 - - 3.351e-235 730.0
HKD1_k127_6313472_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.11e-225 706.0
HKD1_k127_6313472_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 569.0
HKD1_k127_6313472_8 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 445.0
HKD1_k127_6313472_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 428.0
HKD1_k127_6315972_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0 1041.0
HKD1_k127_6315972_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 1.106e-277 862.0
HKD1_k127_6315972_2 CoA-transferase family III - - - 1.142e-235 732.0
HKD1_k127_6315972_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 5.233e-203 637.0
HKD1_k127_6315972_4 Belongs to the binding-protein-dependent transport system permease family K11961 - - 1.318e-202 654.0
HKD1_k127_6315972_5 ABC transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 458.0
HKD1_k127_6315972_6 Periplasmic binding protein domain K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 422.0
HKD1_k127_6315972_7 ATPases associated with a variety of cellular activities K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
HKD1_k127_6389787_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1973.0
HKD1_k127_6389787_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 499.0
HKD1_k127_6389787_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 497.0
HKD1_k127_6389787_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 496.0
HKD1_k127_6389787_4 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 346.0
HKD1_k127_6389787_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 321.0
HKD1_k127_6389787_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001135 282.0
HKD1_k127_6389787_7 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008029 276.0
HKD1_k127_6389787_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
HKD1_k127_6389787_9 - - - - 0.000000000000000000000000000000000000000000000326 185.0
HKD1_k127_64153_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1384.0
HKD1_k127_64153_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1130.0
HKD1_k127_64153_10 alpha beta - - - 0.0000000000000000000000000000138 132.0
HKD1_k127_64153_11 Cold shock K03704 - - 0.00000000000000000000000000313 128.0
HKD1_k127_64153_12 - - - - 0.00000000000000000000008227 113.0
HKD1_k127_64153_13 Phosphopantetheine attachment site K02078 - - 0.00000000000001519 80.0
HKD1_k127_64153_15 MaoC like domain - - - 0.00000001357 65.0
HKD1_k127_64153_17 - - - - 0.000003768 55.0
HKD1_k127_64153_18 Recombinase zinc beta ribbon domain - - - 0.0005888 46.0
HKD1_k127_64153_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 1.238e-219 685.0
HKD1_k127_64153_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K08261,K21620 - 1.1.1.16,1.1.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 419.0
HKD1_k127_64153_4 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 402.0
HKD1_k127_64153_5 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 385.0
HKD1_k127_64153_6 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 302.0
HKD1_k127_64153_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000006994 216.0
HKD1_k127_64153_8 - - - - 0.0000000000000000000000000000000000000001429 154.0
HKD1_k127_64153_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000000005419 128.0
HKD1_k127_64361_0 peptidase M20 - - - 3.023e-218 685.0
HKD1_k127_64361_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.078e-195 613.0
HKD1_k127_64361_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000003169 194.0
HKD1_k127_64361_3 - - - - 0.0000000000000000000000000000000000000000000001492 195.0
HKD1_k127_64361_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000001713 115.0
HKD1_k127_64361_5 Outer membrane protein beta-barrel domain - - - 0.0000000000001125 70.0
HKD1_k127_6451536_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1606.0
HKD1_k127_6451536_1 Sodium/hydrogen exchanger family K03316 - - 0.0 1251.0
HKD1_k127_6451536_10 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 584.0
HKD1_k127_6451536_11 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 579.0
HKD1_k127_6451536_12 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 535.0
HKD1_k127_6451536_13 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 494.0
HKD1_k127_6451536_14 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 490.0
HKD1_k127_6451536_15 Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 438.0
HKD1_k127_6451536_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 378.0
HKD1_k127_6451536_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
HKD1_k127_6451536_19 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
HKD1_k127_6451536_2 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0 1033.0
HKD1_k127_6451536_20 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 283.0
HKD1_k127_6451536_21 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006828 266.0
HKD1_k127_6451536_22 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001215 277.0
HKD1_k127_6451536_23 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006803 248.0
HKD1_k127_6451536_25 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006421 233.0
HKD1_k127_6451536_27 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000005417 197.0
HKD1_k127_6451536_28 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000648 173.0
HKD1_k127_6451536_29 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000001824 164.0
HKD1_k127_6451536_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.501e-287 884.0
HKD1_k127_6451536_30 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000004247 108.0
HKD1_k127_6451536_31 Glutathione S-transferase K11209 - - 0.00000000000000000000004349 98.0
HKD1_k127_6451536_32 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.000000000000000000005991 92.0
HKD1_k127_6451536_33 - - - - 0.0000000000000000001943 91.0
HKD1_k127_6451536_34 Small Multidrug Resistance protein - - - 0.00000005086 61.0
HKD1_k127_6451536_4 FAD linked oxidase domain protein - - - 8.22e-282 876.0
HKD1_k127_6451536_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 2.393e-264 825.0
HKD1_k127_6451536_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.498e-240 754.0
HKD1_k127_6451536_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.552e-233 747.0
HKD1_k127_6451536_8 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 606.0
HKD1_k127_6451536_9 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 607.0
HKD1_k127_64544_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1848.0
HKD1_k127_64544_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 5.154e-280 871.0
HKD1_k127_64544_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 370.0
HKD1_k127_64544_11 protein conserved in bacteria K09987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 362.0
HKD1_k127_64544_12 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 346.0
HKD1_k127_64544_15 Protein of unknown function (DUF1192) - - - 0.000000000000000000000000002156 111.0
HKD1_k127_64544_16 Outer membrane protein beta-barrel domain - - - 0.0000000000001125 70.0
HKD1_k127_64544_17 Major Facilitator Superfamily - - - 0.0000000000001466 70.0
HKD1_k127_64544_2 COG2873 O-acetylhomoserine sulfhydrylase - - - 1.631e-263 815.0
HKD1_k127_64544_3 AAA domain K07028 - - 1.143e-226 717.0
HKD1_k127_64544_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 9.99e-216 673.0
HKD1_k127_64544_5 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 541.0
HKD1_k127_64544_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 519.0
HKD1_k127_64544_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 497.0
HKD1_k127_64544_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 447.0
HKD1_k127_64544_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 370.0
HKD1_k127_6462511_0 MlrC C-terminus - - - 6.829e-288 890.0
HKD1_k127_6462511_1 COG1042 Acyl-CoA synthetase (NDP forming) - - - 5.523e-243 758.0
HKD1_k127_6462511_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 451.0
HKD1_k127_6462511_11 Pfam:Pyridox_oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 349.0
HKD1_k127_6462511_12 Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 335.0
HKD1_k127_6462511_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 303.0
HKD1_k127_6462511_14 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004826 247.0
HKD1_k127_6462511_15 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000001335 235.0
HKD1_k127_6462511_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000001387 248.0
HKD1_k127_6462511_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000001664 234.0
HKD1_k127_6462511_18 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
HKD1_k127_6462511_19 Transcriptional regulator, MarR family - - - 0.00000000000000000000000000000000000000000000000000000007768 214.0
HKD1_k127_6462511_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.884e-223 697.0
HKD1_k127_6462511_20 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000003233 211.0
HKD1_k127_6462511_21 Lipase (class 2) K01046 - 3.1.1.3 0.0007936 44.0
HKD1_k127_6462511_3 oxidoreductase FAD NAD(P)-binding domain protein K14581 - 1.18.1.7 2.958e-200 638.0
HKD1_k127_6462511_4 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 537.0
HKD1_k127_6462511_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
HKD1_k127_6462511_6 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 505.0
HKD1_k127_6462511_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 511.0
HKD1_k127_6462511_8 Phenylacetic acid catabolic protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 450.0
HKD1_k127_6462511_9 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 444.0
HKD1_k127_6489501_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0 1054.0
HKD1_k127_6489501_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0 1052.0
HKD1_k127_6489501_10 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 531.0
HKD1_k127_6489501_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 524.0
HKD1_k127_6489501_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 505.0
HKD1_k127_6489501_13 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 515.0
HKD1_k127_6489501_14 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 487.0
HKD1_k127_6489501_15 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 463.0
HKD1_k127_6489501_16 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 391.0
HKD1_k127_6489501_17 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
HKD1_k127_6489501_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
HKD1_k127_6489501_19 2-hydroxy-3-oxopropionate reductase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 306.0
HKD1_k127_6489501_2 glutamine synthetase K01915 - 6.3.1.2 1.74e-274 869.0
HKD1_k127_6489501_20 SnoaL-like polyketide cyclase K07255 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
HKD1_k127_6489501_21 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000004744 211.0
HKD1_k127_6489501_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000006547 153.0
HKD1_k127_6489501_23 - - - - 0.00000000000000000000000000000001863 144.0
HKD1_k127_6489501_24 tolerance protein K03926 - - 0.0000000000000000000000000001032 120.0
HKD1_k127_6489501_27 Phospholipase D. Active site motifs. - - - 0.0007077 51.0
HKD1_k127_6489501_3 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 1.826e-269 833.0
HKD1_k127_6489501_4 Belongs to the amidase family - - - 1.878e-263 827.0
HKD1_k127_6489501_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 604.0
HKD1_k127_6489501_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 586.0
HKD1_k127_6489501_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 591.0
HKD1_k127_6489501_8 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 589.0
HKD1_k127_6489501_9 Methionine synthase K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 571.0
HKD1_k127_6490383_0 Mechanosensitive ion channel - - - 1.635e-253 801.0
HKD1_k127_6490383_1 Metallo-beta-lactamase superfamily - - - 1.819e-216 673.0
HKD1_k127_6490383_2 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 548.0
HKD1_k127_6490383_3 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 514.0
HKD1_k127_6490383_4 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 481.0
HKD1_k127_6490383_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000002557 149.0
HKD1_k127_6524655_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 8.513e-297 919.0
HKD1_k127_6524655_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 577.0
HKD1_k127_6524655_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 578.0
HKD1_k127_6524655_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 530.0
HKD1_k127_6524655_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 525.0
HKD1_k127_6524655_5 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 431.0
HKD1_k127_6524655_6 Protein of unknown function (DUF559) - - - 0.00000000000000000000000004308 113.0
HKD1_k127_6529827_0 Rhodanese Homology Domain - - - 0.0 1270.0
HKD1_k127_6529827_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 4.656e-298 925.0
HKD1_k127_6529827_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000001565 158.0
HKD1_k127_6529827_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000302 147.0
HKD1_k127_6529827_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000006342 118.0
HKD1_k127_6529827_14 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000002256 115.0
HKD1_k127_6529827_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000005375 107.0
HKD1_k127_6529827_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000001813 111.0
HKD1_k127_6529827_17 Transcriptional regulator K18297 - - 0.0000000000000000000001745 105.0
HKD1_k127_6529827_18 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000004329 68.0
HKD1_k127_6529827_19 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000003467 60.0
HKD1_k127_6529827_2 Elongator protein 3, MiaB family, Radical SAM - - - 4.18e-203 637.0
HKD1_k127_6529827_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 340.0
HKD1_k127_6529827_4 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 315.0
HKD1_k127_6529827_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 315.0
HKD1_k127_6529827_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 307.0
HKD1_k127_6529827_7 Protein conserved in bacteria K09962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001837 282.0
HKD1_k127_6529827_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000003383 233.0
HKD1_k127_6529827_9 YqcI/YcgG family - - - 0.0000000000000000000000000000000000000000000000000000000001567 211.0
HKD1_k127_6551321_0 Luciferase-like monooxygenase - - - 7.625e-201 627.0
HKD1_k127_6551321_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 503.0
HKD1_k127_6588227_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.0 1303.0
HKD1_k127_6588227_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.373e-222 717.0
HKD1_k127_6588227_10 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 453.0
HKD1_k127_6588227_11 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 394.0
HKD1_k127_6588227_12 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 385.0
HKD1_k127_6588227_13 Aconitase family (aconitate hydratase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 370.0
HKD1_k127_6588227_14 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 368.0
HKD1_k127_6588227_15 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
HKD1_k127_6588227_16 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
HKD1_k127_6588227_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002368 229.0
HKD1_k127_6588227_18 Domain of unknown function (DUF1127) - - - 0.0000000000000000000007188 99.0
HKD1_k127_6588227_19 Domain of unknown function (DUF1127) - - - 0.0000002265 54.0
HKD1_k127_6588227_2 Luciferase-like monooxygenase - - - 3.469e-220 685.0
HKD1_k127_6588227_3 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 596.0
HKD1_k127_6588227_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 557.0
HKD1_k127_6588227_5 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 564.0
HKD1_k127_6588227_6 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 546.0
HKD1_k127_6588227_7 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 497.0
HKD1_k127_6588227_8 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 481.0
HKD1_k127_6588227_9 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
HKD1_k127_6618804_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1157.0
HKD1_k127_6618804_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 578.0
HKD1_k127_6618804_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 486.0
HKD1_k127_6618804_3 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 409.0
HKD1_k127_6618804_4 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004657 289.0
HKD1_k127_6618804_5 - - - - 0.00000000000000000000000000000000000000000000001925 174.0
HKD1_k127_6618804_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000000000000002748 144.0
HKD1_k127_6618804_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000002503 139.0
HKD1_k127_6618804_8 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000000001801 80.0
HKD1_k127_6646909_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1154.0
HKD1_k127_6646909_1 CoA-transferase family III - - - 2.279e-226 705.0
HKD1_k127_6646909_2 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000005799 153.0
HKD1_k127_666279_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00986,K15342 - 2.7.7.49 5.117e-235 734.0
HKD1_k127_666279_1 Dehydratase large subunit K01699 - 4.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 573.0
HKD1_k127_666279_2 Dehydratase small subunit K13920 - 4.2.1.28 0.00000000000000000000000000000000000000001027 163.0
HKD1_k127_666279_3 reverse transcriptase - - - 0.00000000000000002243 83.0
HKD1_k127_6680015_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 1.88e-303 937.0
HKD1_k127_6680015_1 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 590.0
HKD1_k127_6680015_10 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000435 167.0
HKD1_k127_6680015_11 BON domain - - - 0.00000000000000000000504 98.0
HKD1_k127_6680015_13 Macrocin-O-methyltransferase (TylF) - - - 0.000000000000342 81.0
HKD1_k127_6680015_15 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000001044 72.0
HKD1_k127_6680015_16 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000005044 61.0
HKD1_k127_6680015_17 - - - - 0.0002234 53.0
HKD1_k127_6680015_2 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 499.0
HKD1_k127_6680015_3 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 432.0
HKD1_k127_6680015_4 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 378.0
HKD1_k127_6680015_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 353.0
HKD1_k127_6680015_6 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
HKD1_k127_6680015_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
HKD1_k127_6680015_8 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002121 179.0
HKD1_k127_6680015_9 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000004257 173.0
HKD1_k127_6737488_0 Belongs to the peptidase S16 family - - - 1.046e-277 879.0
HKD1_k127_6737488_1 COG4618 ABC-type protease lipase transport system, ATPase and permease components K16299 - - 2.563e-269 861.0
HKD1_k127_6737488_10 - - - - 0.0000000000000000000005513 113.0
HKD1_k127_6737488_11 Phosphopantetheine attachment site - - - 0.000000000002125 80.0
HKD1_k127_6737488_2 COG0845 Membrane-fusion protein K16300 - - 2.567e-207 653.0
HKD1_k127_6737488_3 - - - - 1.559e-204 677.0
HKD1_k127_6737488_4 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 3.264e-202 631.0
HKD1_k127_6737488_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 385.0
HKD1_k127_6737488_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 339.0
HKD1_k127_6737488_7 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000000000006955 193.0
HKD1_k127_6737488_8 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000007281 192.0
HKD1_k127_6737488_9 Aminotransferase class-III - - - 0.000000000000000000000000000000002876 128.0
HKD1_k127_6739333_0 Transport of potassium into the cell K03549 - - 0.0 1001.0
HKD1_k127_6739333_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 9.141e-291 901.0
HKD1_k127_6739333_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 541.0
HKD1_k127_6739333_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 524.0
HKD1_k127_6739333_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000009489 189.0
HKD1_k127_6777742_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2886.0
HKD1_k127_6777742_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1310.0
HKD1_k127_6777742_10 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 503.0
HKD1_k127_6777742_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 486.0
HKD1_k127_6777742_12 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 485.0
HKD1_k127_6777742_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 472.0
HKD1_k127_6777742_14 Molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 459.0
HKD1_k127_6777742_15 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 438.0
HKD1_k127_6777742_16 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 440.0
HKD1_k127_6777742_17 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
HKD1_k127_6777742_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 406.0
HKD1_k127_6777742_19 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 374.0
HKD1_k127_6777742_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 1.177e-291 898.0
HKD1_k127_6777742_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 376.0
HKD1_k127_6777742_21 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
HKD1_k127_6777742_22 Dehydroquinase class II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005906 253.0
HKD1_k127_6777742_23 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000001341 234.0
HKD1_k127_6777742_24 NADPH-quinone reductase (modulator of drug activity B) - - - 0.000000000000000000000000000000000000000000000000000000000000001163 224.0
HKD1_k127_6777742_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003784 230.0
HKD1_k127_6777742_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002956 194.0
HKD1_k127_6777742_27 RNA signal recognition particle 4.5S RNA - - - 0.000000000000000000000000000000000000000000000000001076 185.0
HKD1_k127_6777742_29 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000000000000000000001229 166.0
HKD1_k127_6777742_3 Belongs to the TPP enzyme family K00156 - 1.2.5.1 2.185e-268 837.0
HKD1_k127_6777742_30 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.000000000000000000000000000000000000000005635 163.0
HKD1_k127_6777742_31 Glutathione-dependent formaldehyde-activating enzyme family protein 3 - - - 0.00000000000000000000000000000000006404 139.0
HKD1_k127_6777742_32 - - - - 0.0000000000000000000000007696 112.0
HKD1_k127_6777742_34 Molecular chaperone - - - 0.0000000000000005283 78.0
HKD1_k127_6777742_35 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000001071 60.0
HKD1_k127_6777742_4 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.561e-251 781.0
HKD1_k127_6777742_5 Acyl-CoA dehydrogenase, middle domain - - - 4.775e-246 762.0
HKD1_k127_6777742_6 Cytochrome P450 - - - 1.642e-245 761.0
HKD1_k127_6777742_8 Beta-eliminating lyase K01620 - 4.1.2.48 2.497e-198 631.0
HKD1_k127_6777742_9 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 602.0
HKD1_k127_6787925_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1603.0
HKD1_k127_6787925_1 ABC transporter transmembrane region K02021 - - 0.0 1554.0
HKD1_k127_6787925_10 Glycosyl transferases group 1 - - - 1.395e-206 657.0
HKD1_k127_6787925_11 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 1.369e-202 639.0
HKD1_k127_6787925_12 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 9.753e-200 636.0
HKD1_k127_6787925_13 Gram-negative porin K08720 - - 1.254e-198 629.0
HKD1_k127_6787925_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 561.0
HKD1_k127_6787925_15 membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 544.0
HKD1_k127_6787925_16 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 544.0
HKD1_k127_6787925_17 COG0708 Exonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 509.0
HKD1_k127_6787925_18 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 501.0
HKD1_k127_6787925_19 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 489.0
HKD1_k127_6787925_2 DNA ligase K01971 - 6.5.1.1 0.0 1346.0
HKD1_k127_6787925_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 469.0
HKD1_k127_6787925_21 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 462.0
HKD1_k127_6787925_22 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 462.0
HKD1_k127_6787925_23 Bacterial periplasmic substrate-binding proteins K10018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 466.0
HKD1_k127_6787925_24 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 452.0
HKD1_k127_6787925_25 (Fe-S) oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 448.0
HKD1_k127_6787925_26 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
HKD1_k127_6787925_27 Encapsulating protein for peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 433.0
HKD1_k127_6787925_28 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 415.0
HKD1_k127_6787925_29 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 382.0
HKD1_k127_6787925_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1074.0
HKD1_k127_6787925_30 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
HKD1_k127_6787925_31 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 350.0
HKD1_k127_6787925_32 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 347.0
HKD1_k127_6787925_33 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 307.0
HKD1_k127_6787925_34 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 280.0
HKD1_k127_6787925_35 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
HKD1_k127_6787925_36 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003931 263.0
HKD1_k127_6787925_37 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005195 245.0
HKD1_k127_6787925_38 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22316 - 3.1.26.4,3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000007703 250.0
HKD1_k127_6787925_39 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003328 242.0
HKD1_k127_6787925_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1052.0
HKD1_k127_6787925_40 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000000000000000000000000000000000000000000000000000000000000496 217.0
HKD1_k127_6787925_41 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17202,K17205,K17213 - - 0.0000000000000000000000000000000000000000000000000000000001474 214.0
HKD1_k127_6787925_42 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000003804 186.0
HKD1_k127_6787925_43 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000482 171.0
HKD1_k127_6787925_44 Transglycosylase associated protein - - - 0.0000000000000000000000000000001298 124.0
HKD1_k127_6787925_45 photosystem II stabilization K02237 - - 0.00000000000000000000000000000406 124.0
HKD1_k127_6787925_5 LUD domain K18929 - - 4.684e-281 876.0
HKD1_k127_6787925_6 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 5.367e-249 775.0
HKD1_k127_6787925_7 Glycosyltransferase family 28 C-terminal domain - - - 2.504e-235 734.0
HKD1_k127_6787925_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 8.233e-221 698.0
HKD1_k127_6787925_9 Involved in the biosynthesis of porphyrin-containing compound - - - 1.717e-209 656.0
HKD1_k127_683314_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 5.473e-317 972.0
HKD1_k127_683314_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.67e-313 964.0
HKD1_k127_683314_2 L-carnitine dehydratase bile acid-inducible protein F - - - 7.466e-234 726.0
HKD1_k127_683314_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 1.895e-212 663.0
HKD1_k127_683314_5 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 320.0
HKD1_k127_683314_6 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 298.0
HKD1_k127_683314_7 Cupin domain - - - 0.0000000000000000000000000000000000000157 154.0
HKD1_k127_6833987_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1122.0
HKD1_k127_6833987_1 Adenylate cyclase - - - 8.143e-219 689.0
HKD1_k127_6833987_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 1.991e-210 663.0
HKD1_k127_6833987_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 546.0
HKD1_k127_6833987_4 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000002284 88.0
HKD1_k127_6840512_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 8.042e-294 904.0
HKD1_k127_6840512_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.255e-249 802.0
HKD1_k127_6840512_10 PFAM NUDIX hydrolase K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.6.1.67 0.00000000000000000000000000000000000000000007723 161.0
HKD1_k127_6840512_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000002283 161.0
HKD1_k127_6840512_12 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000000000005908 162.0
HKD1_k127_6840512_13 - - - - 0.0000000000000000000000003802 106.0
HKD1_k127_6840512_15 Protein conserved in bacteria K09914 - - 0.000008878 56.0
HKD1_k127_6840512_2 Vacuole effluxer Atg22 like K06902 - - 1.092e-247 771.0
HKD1_k127_6840512_3 Haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 470.0
HKD1_k127_6840512_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 426.0
HKD1_k127_6840512_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 431.0
HKD1_k127_6840512_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 397.0
HKD1_k127_6840512_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
HKD1_k127_6840512_8 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003775 239.0
HKD1_k127_6840512_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000001103 173.0
HKD1_k127_6858825_0 Carbohydrate-selective porin, OprB family K16080 - - 0.0 1046.0
HKD1_k127_6858825_1 Carbohydrate-selective porin, OprB family K16080 - - 3.227e-274 858.0
HKD1_k127_6858825_10 - - - - 0.0000000000000000000000000000000000000000000000001608 187.0
HKD1_k127_6858825_11 Protein of unknown function (DUF1636) - - - 0.0000000000000000000000000000000000000000008086 168.0
HKD1_k127_6858825_12 - - - - 0.00000000000000000000000000000000002257 138.0
HKD1_k127_6858825_13 Probable cobalt transporter subunit (CbtB) - - - 0.000000000001303 79.0
HKD1_k127_6858825_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.147e-237 746.0
HKD1_k127_6858825_3 Uncharacterized ACR, YdiU/UPF0061 family - - - 8.616e-234 732.0
HKD1_k127_6858825_4 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 590.0
HKD1_k127_6858825_5 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 483.0
HKD1_k127_6858825_6 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 423.0
HKD1_k127_6858825_7 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K02225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 419.0
HKD1_k127_6858825_8 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 334.0
HKD1_k127_6858825_9 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
HKD1_k127_6859852_0 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1011.0
HKD1_k127_6859852_1 Hydantoinase B/oxoprolinase - - - 6.688e-312 966.0
HKD1_k127_6859852_2 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 5.738e-266 824.0
HKD1_k127_6859852_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 462.0
HKD1_k127_6859852_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 457.0
HKD1_k127_6859852_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 417.0
HKD1_k127_6859852_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
HKD1_k127_6859852_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
HKD1_k127_6859852_8 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
HKD1_k127_6859852_9 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000000000000000000000000000000001358 155.0
HKD1_k127_690528_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1348.0
HKD1_k127_690528_1 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 7.474e-284 877.0
HKD1_k127_690528_10 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000006883 231.0
HKD1_k127_690528_2 Branched-chain amino acid transport system / permease component - - - 9.359e-243 766.0
HKD1_k127_690528_3 von Willebrand factor (vWF) type A domain - - - 2.542e-230 747.0
HKD1_k127_690528_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
HKD1_k127_690528_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 516.0
HKD1_k127_690528_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 488.0
HKD1_k127_690528_7 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 401.0
HKD1_k127_690528_8 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 385.0
HKD1_k127_690528_9 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 331.0
HKD1_k127_6925306_0 COG0591 Na proline symporter - - - 0.0 1812.0
HKD1_k127_6925306_1 Methionine synthase K00548 - 2.1.1.13 0.0 1587.0
HKD1_k127_6925306_10 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.175e-236 739.0
HKD1_k127_6925306_11 Acyl-CoA dehydrogenase, middle domain - - - 5.349e-229 711.0
HKD1_k127_6925306_12 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.434e-226 711.0
HKD1_k127_6925306_13 COG1530 Ribonucleases G and E K08300,K08301 - 3.1.26.12 1.486e-216 681.0
HKD1_k127_6925306_14 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase - - - 2.475e-212 670.0
HKD1_k127_6925306_15 Homocysteine S-methyltransferase K00548 - 2.1.1.13 1.959e-202 639.0
HKD1_k127_6925306_16 CoA-transferase family III - - - 2.833e-202 645.0
HKD1_k127_6925306_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 601.0
HKD1_k127_6925306_18 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 529.0
HKD1_k127_6925306_19 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 529.0
HKD1_k127_6925306_2 SNF2 family N-terminal domain - - - 0.0 1227.0
HKD1_k127_6925306_20 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 487.0
HKD1_k127_6925306_21 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 434.0
HKD1_k127_6925306_22 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 423.0
HKD1_k127_6925306_23 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 428.0
HKD1_k127_6925306_24 thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 437.0
HKD1_k127_6925306_25 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 417.0
HKD1_k127_6925306_26 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 399.0
HKD1_k127_6925306_27 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 400.0
HKD1_k127_6925306_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 409.0
HKD1_k127_6925306_29 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 374.0
HKD1_k127_6925306_3 Acyclic terpene utilisation family protein AtuA - - - 0.0 1064.0
HKD1_k127_6925306_30 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
HKD1_k127_6925306_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 352.0
HKD1_k127_6925306_32 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 350.0
HKD1_k127_6925306_33 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 328.0
HKD1_k127_6925306_34 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 329.0
HKD1_k127_6925306_35 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 302.0
HKD1_k127_6925306_36 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
HKD1_k127_6925306_37 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
HKD1_k127_6925306_38 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 265.0
HKD1_k127_6925306_39 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003735 261.0
HKD1_k127_6925306_4 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.0 1034.0
HKD1_k127_6925306_40 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HKD1_k127_6925306_41 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001729 265.0
HKD1_k127_6925306_42 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 252.0
HKD1_k127_6925306_43 Bacterial regulatory helix-turn-helix protein, lysR family K02623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001726 259.0
HKD1_k127_6925306_45 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
HKD1_k127_6925306_46 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009142 232.0
HKD1_k127_6925306_47 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000008721 205.0
HKD1_k127_6925306_48 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001903 186.0
HKD1_k127_6925306_49 Alpha beta hydrolase K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000001178 180.0
HKD1_k127_6925306_5 His Kinase A (phosphoacceptor) domain - - - 8.451e-270 848.0
HKD1_k127_6925306_50 Fusaric acid resistance protein-like - - - 0.000000000000000000000000000000000000000001246 175.0
HKD1_k127_6925306_51 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002031 147.0
HKD1_k127_6925306_52 - - - - 0.0000000000000000000000000000000002475 138.0
HKD1_k127_6925306_53 CoA-transferase family III - - - 0.000000000000000000000000000007172 119.0
HKD1_k127_6925306_55 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000000000008084 111.0
HKD1_k127_6925306_6 Acyl-CoA dehydrogenase, middle domain - - - 1.325e-257 796.0
HKD1_k127_6925306_7 Acyl-CoA dehydrogenase, middle domain - - - 6.479e-250 777.0
HKD1_k127_6925306_8 Sugar (and other) transporter - - - 5.332e-247 780.0
HKD1_k127_6925306_9 CoA-transferase family III - - - 2.101e-243 761.0
HKD1_k127_6927167_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0 1068.0
HKD1_k127_6927167_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.472e-301 931.0
HKD1_k127_6927167_10 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 339.0
HKD1_k127_6927167_11 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 269.0
HKD1_k127_6927167_12 PFAM MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001664 259.0
HKD1_k127_6927167_13 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002276 237.0
HKD1_k127_6927167_14 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD1_k127_6927167_15 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000005645 216.0
HKD1_k127_6927167_16 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000779 206.0
HKD1_k127_6927167_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000001188 168.0
HKD1_k127_6927167_19 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000002695 134.0
HKD1_k127_6927167_2 Amidase K01426 - 3.5.1.4 6.191e-249 780.0
HKD1_k127_6927167_20 Protein of unknown function (DUF3987) - - - 0.00000000000000000000000000001539 136.0
HKD1_k127_6927167_21 Response regulator, receiver - - - 0.00000000000000000000000011 113.0
HKD1_k127_6927167_22 transposase activity - - - 0.0000000000000000003192 95.0
HKD1_k127_6927167_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 4.545e-246 765.0
HKD1_k127_6927167_4 III protein, CoA-transferase family - - - 3.82e-223 696.0
HKD1_k127_6927167_5 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.618e-207 684.0
HKD1_k127_6927167_6 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 507.0
HKD1_k127_6927167_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
HKD1_k127_6927167_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
HKD1_k127_6927167_9 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 362.0
HKD1_k127_6936164_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 522.0
HKD1_k127_6936164_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 443.0
HKD1_k127_6936164_2 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 377.0
HKD1_k127_6936164_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
HKD1_k127_6936164_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000000000000000002929 224.0
HKD1_k127_6936164_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000001617 201.0
HKD1_k127_6936164_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000002733 176.0
HKD1_k127_6936164_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000000001093 177.0
HKD1_k127_6961832_0 COG3293 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 404.0
HKD1_k127_6961832_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
HKD1_k127_6961832_2 Cyanophycin synthetase - - - 0.0000000000000000000000000000000000000008199 162.0
HKD1_k127_6961832_3 Methyltransferase domain - - - 0.0000000000002729 74.0
HKD1_k127_6961832_4 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000007005 54.0
HKD1_k127_6964624_0 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 5.603e-258 797.0
HKD1_k127_6964624_1 Histidine kinase - - - 6.778e-224 703.0
HKD1_k127_6964624_2 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 561.0
HKD1_k127_6964624_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000007657 178.0
HKD1_k127_6964624_4 Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000003942 154.0
HKD1_k127_6980666_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 472.0
HKD1_k127_6980666_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 451.0
HKD1_k127_6980666_2 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006387 276.0
HKD1_k127_6980666_3 Belongs to the HesB IscA family K15724 - - 0.0000000000003376 68.0
HKD1_k127_6988989_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1360.0
HKD1_k127_6988989_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 2.147e-319 981.0
HKD1_k127_6988989_10 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 457.0
HKD1_k127_6988989_11 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 446.0
HKD1_k127_6988989_12 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 438.0
HKD1_k127_6988989_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 420.0
HKD1_k127_6988989_14 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 395.0
HKD1_k127_6988989_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 400.0
HKD1_k127_6988989_16 GHMP kinases N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 366.0
HKD1_k127_6988989_17 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 356.0
HKD1_k127_6988989_19 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 332.0
HKD1_k127_6988989_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 2.253e-257 799.0
HKD1_k127_6988989_20 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
HKD1_k127_6988989_21 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
HKD1_k127_6988989_22 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001184 293.0
HKD1_k127_6988989_23 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
HKD1_k127_6988989_24 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005395 277.0
HKD1_k127_6988989_25 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002688 274.0
HKD1_k127_6988989_26 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001388 254.0
HKD1_k127_6988989_27 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000004789 248.0
HKD1_k127_6988989_28 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000001893 214.0
HKD1_k127_6988989_29 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000002079 203.0
HKD1_k127_6988989_3 Major Facilitator Superfamily - - - 5.65e-226 705.0
HKD1_k127_6988989_30 transposase activity - - - 0.00000000000000000000000000000002038 141.0
HKD1_k127_6988989_31 Methyltransferase FkbM domain - - - 0.00000000000000003116 91.0
HKD1_k127_6988989_4 Chaperone SurA K03771 - 5.2.1.8 1.336e-194 615.0
HKD1_k127_6988989_5 radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 556.0
HKD1_k127_6988989_6 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 553.0
HKD1_k127_6988989_7 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 546.0
HKD1_k127_6988989_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 490.0
HKD1_k127_6988989_9 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 496.0
HKD1_k127_6993299_0 Bacterial extracellular solute-binding protein - - - 1.868e-234 734.0
HKD1_k127_6993299_1 Aminotransferase class I and II - - - 1.33e-230 719.0
HKD1_k127_6993299_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 8.777e-227 711.0
HKD1_k127_6993299_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 554.0
HKD1_k127_6993299_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 547.0
HKD1_k127_6993299_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 424.0
HKD1_k127_6993299_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 372.0
HKD1_k127_6993299_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
HKD1_k127_6993299_8 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 303.0
HKD1_k127_6996043_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.0 1077.0
HKD1_k127_6996043_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.675e-240 745.0
HKD1_k127_6996043_10 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000001253 70.0
HKD1_k127_6996043_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 3.555e-206 649.0
HKD1_k127_6996043_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 271.0
HKD1_k127_6996043_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001043 252.0
HKD1_k127_6996043_6 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000184 218.0
HKD1_k127_6996043_7 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000000000002165 239.0
HKD1_k127_6996043_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000008061 145.0
HKD1_k127_7043986_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 2.547e-242 756.0
HKD1_k127_7043986_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 6.67e-237 742.0
HKD1_k127_7043986_10 Ras of Complex, Roc, domain of DAPkinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002872 261.0
HKD1_k127_7043986_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001329 250.0
HKD1_k127_7043986_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD1_k127_7043986_13 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000003384 138.0
HKD1_k127_7043986_14 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000009708 123.0
HKD1_k127_7043986_15 - K11477 - - 0.000000000000000000000000002513 116.0
HKD1_k127_7043986_16 Amidohydrolase family K06015 - 3.5.1.81 0.0000001722 53.0
HKD1_k127_7043986_2 OmpA family - - - 8.317e-227 719.0
HKD1_k127_7043986_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 495.0
HKD1_k127_7043986_4 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 475.0
HKD1_k127_7043986_5 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 479.0
HKD1_k127_7043986_6 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 365.0
HKD1_k127_7043986_7 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 365.0
HKD1_k127_7043986_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 295.0
HKD1_k127_7043986_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001911 284.0
HKD1_k127_7049615_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.316e-254 787.0
HKD1_k127_7049615_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.326e-224 698.0
HKD1_k127_7049615_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 548.0
HKD1_k127_7049615_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 367.0
HKD1_k127_7049615_4 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
HKD1_k127_7049615_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000001494 217.0
HKD1_k127_70501_0 Autotransporter beta-domain - - - 2.556e-272 885.0
HKD1_k127_70501_1 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 5.28e-258 824.0
HKD1_k127_70501_10 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 598.0
HKD1_k127_70501_11 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 569.0
HKD1_k127_70501_12 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 519.0
HKD1_k127_70501_13 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 493.0
HKD1_k127_70501_14 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 470.0
HKD1_k127_70501_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 459.0
HKD1_k127_70501_16 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 428.0
HKD1_k127_70501_17 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 403.0
HKD1_k127_70501_18 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000001229 211.0
HKD1_k127_70501_19 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000006443 222.0
HKD1_k127_70501_2 Ammonium transporter K03320 - - 5.669e-250 778.0
HKD1_k127_70501_20 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000006855 200.0
HKD1_k127_70501_3 COG0004 Ammonia permease K03320 - - 2.166e-245 766.0
HKD1_k127_70501_4 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 5.235e-223 698.0
HKD1_k127_70501_5 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 9e-213 666.0
HKD1_k127_70501_6 Acetyl-coenzyme A transporter 1 K08218 - - 1.197e-203 647.0
HKD1_k127_70501_7 Major facilitator superfamily K07552 - - 6.966e-200 629.0
HKD1_k127_70501_8 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 604.0
HKD1_k127_70501_9 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 602.0
HKD1_k127_7108780_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 3.437e-247 764.0
HKD1_k127_7108780_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 1.369e-243 760.0
HKD1_k127_7108780_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000001039 198.0
HKD1_k127_7108780_11 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000001845 196.0
HKD1_k127_7108780_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001076 183.0
HKD1_k127_7108780_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001878 137.0
HKD1_k127_7108780_14 rubredoxin - - - 0.00000000000000000000000008409 112.0
HKD1_k127_7108780_15 - - - - 0.00000001472 59.0
HKD1_k127_7108780_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 600.0
HKD1_k127_7108780_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 533.0
HKD1_k127_7108780_4 drug resistance transporter, Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 510.0
HKD1_k127_7108780_5 Methyl-transferase K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 494.0
HKD1_k127_7108780_6 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 427.0
HKD1_k127_7108780_7 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
HKD1_k127_7108780_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
HKD1_k127_7108780_9 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
HKD1_k127_7123858_0 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 8.08e-217 677.0
HKD1_k127_7123858_1 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 582.0
HKD1_k127_7123858_2 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD1_k127_7144393_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 1.47e-243 755.0
HKD1_k127_7144393_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.003e-211 662.0
HKD1_k127_7144393_2 Transketolase, pyrimidine binding domain K21417 - - 2.731e-208 673.0
HKD1_k127_7144393_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) - - - 1.353e-198 628.0
HKD1_k127_7144393_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 387.0
HKD1_k127_7149138_0 Psort location CytoplasmicMembrane, score K17686 - 3.6.3.54 0.0 1041.0
HKD1_k127_7149138_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 604.0
HKD1_k127_7149138_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000004296 214.0
HKD1_k127_7149138_3 Ribosomal protein L11 methyltransferase (PrmA) K05929 - 2.1.1.103 0.00000000000000000000000000000000000000002253 177.0
HKD1_k127_7150585_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.276e-295 913.0
HKD1_k127_7150585_1 Psort location Cytoplasmic, score 7.50 - - - 1.113e-255 790.0
HKD1_k127_7150585_10 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
HKD1_k127_7150585_11 Acetyltransferase (GNAT) domain K22479 - - 0.000000000000000000000000000000000000000000000000002732 193.0
HKD1_k127_7150585_12 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000002089 177.0
HKD1_k127_7150585_13 Transposase IS200 like - - - 0.00000001026 57.0
HKD1_k127_7150585_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 1.018e-197 620.0
HKD1_k127_7150585_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 552.0
HKD1_k127_7150585_4 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 534.0
HKD1_k127_7150585_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 524.0
HKD1_k127_7150585_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 522.0
HKD1_k127_7150585_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 474.0
HKD1_k127_7150585_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 453.0
HKD1_k127_7150585_9 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004033 263.0
HKD1_k127_7159421_0 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 7.617e-283 899.0
HKD1_k127_7159421_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 604.0
HKD1_k127_7159421_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 569.0
HKD1_k127_7159421_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 487.0
HKD1_k127_7159421_4 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
HKD1_k127_7159421_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 299.0
HKD1_k127_7159421_6 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 288.0
HKD1_k127_7159421_7 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000001569 120.0
HKD1_k127_7178486_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1690.0
HKD1_k127_7178486_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1113.0
HKD1_k127_7178486_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000436 178.0
HKD1_k127_7179783_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2792.0
HKD1_k127_7179783_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 1.615e-239 743.0
HKD1_k127_7179783_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 381.0
HKD1_k127_7179783_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 371.0
HKD1_k127_7179783_4 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 330.0
HKD1_k127_7179783_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004023 282.0
HKD1_k127_7179783_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000001195 148.0
HKD1_k127_7179783_7 Tautomerase enzyme - - - 0.000000000000000000000000000005864 119.0
HKD1_k127_7188581_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1007.0
HKD1_k127_7188581_1 Adenylate cyclase K01768 - 4.6.1.1 4.476e-268 841.0
HKD1_k127_7188581_2 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 509.0
HKD1_k127_7188581_3 Major intrinsic protein K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 360.0
HKD1_k127_7192208_0 DNA polymerase beta thumb K02347 - - 5.01e-212 673.0
HKD1_k127_7192208_1 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 552.0
HKD1_k127_7192208_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 426.0
HKD1_k127_7192208_3 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 334.0
HKD1_k127_7192208_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 317.0
HKD1_k127_7192208_5 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 287.0
HKD1_k127_7192208_6 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HKD1_k127_7192208_7 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000009415 190.0
HKD1_k127_7199200_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 6.428e-230 718.0
HKD1_k127_7199200_1 Major Facilitator Superfamily - - - 3.69e-205 646.0
HKD1_k127_7199200_10 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 322.0
HKD1_k127_7199200_11 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 297.0
HKD1_k127_7199200_12 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
HKD1_k127_7199200_13 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000006843 169.0
HKD1_k127_7199200_14 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000000002129 98.0
HKD1_k127_7199200_15 YCII-related domain - - - 0.0000000000000000002817 92.0
HKD1_k127_7199200_16 YCII-related domain - - - 0.00003051 52.0
HKD1_k127_7199200_17 YCII-related domain - - - 0.00005899 51.0
HKD1_k127_7199200_2 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 1.243e-204 661.0
HKD1_k127_7199200_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 572.0
HKD1_k127_7199200_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 543.0
HKD1_k127_7199200_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 508.0
HKD1_k127_7199200_6 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 476.0
HKD1_k127_7199200_7 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 439.0
HKD1_k127_7199200_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
HKD1_k127_7199200_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 377.0
HKD1_k127_7200175_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1497.0
HKD1_k127_7200175_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0 1100.0
HKD1_k127_7200175_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 365.0
HKD1_k127_7200175_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 359.0
HKD1_k127_7200175_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004928 258.0
HKD1_k127_7200175_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000007243 182.0
HKD1_k127_7245718_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.36e-296 930.0
HKD1_k127_7245718_1 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
HKD1_k127_7245718_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 319.0
HKD1_k127_7245718_3 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000009492 91.0
HKD1_k127_7245718_4 Propeptide PepSY amd peptidase M4 - - - 0.000000000002279 72.0
HKD1_k127_7245718_5 Domain of unknown function (DUF1476) - - - 0.000000007271 63.0
HKD1_k127_7290212_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 447.0
HKD1_k127_7290212_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 418.0
HKD1_k127_7290212_2 protein containing LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 404.0
HKD1_k127_7290212_3 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 322.0
HKD1_k127_7290212_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 276.0
HKD1_k127_7290212_5 COG0558 Phosphatidylglycerophosphate synthase - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
HKD1_k127_7290212_6 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000005665 190.0
HKD1_k127_7290212_8 Type IV leader peptidase family - - - 0.00000000187 66.0
HKD1_k127_7290212_9 Pilus assembly protein CpaD K02281 - - 0.0006129 51.0
HKD1_k127_7292051_0 Belongs to the aldehyde dehydrogenase family - - - 5.8e-278 864.0
HKD1_k127_7292051_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.173e-238 737.0
HKD1_k127_7292051_10 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 521.0
HKD1_k127_7292051_11 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 518.0
HKD1_k127_7292051_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 507.0
HKD1_k127_7292051_13 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 482.0
HKD1_k127_7292051_14 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
HKD1_k127_7292051_15 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 459.0
HKD1_k127_7292051_16 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 439.0
HKD1_k127_7292051_17 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 425.0
HKD1_k127_7292051_18 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 406.0
HKD1_k127_7292051_19 Belongs to the mandelate racemase muconate lactonizing enzyme family K01856 - 5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
HKD1_k127_7292051_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.224e-232 732.0
HKD1_k127_7292051_20 DJ-1/PfpI family K18199 - 4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 374.0
HKD1_k127_7292051_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 362.0
HKD1_k127_7292051_22 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 361.0
HKD1_k127_7292051_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 325.0
HKD1_k127_7292051_24 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 319.0
HKD1_k127_7292051_25 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 327.0
HKD1_k127_7292051_26 Steryl acetyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
HKD1_k127_7292051_27 ATPases associated with a variety of cellular activities K02028,K02029,K09972,K10004 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 295.0
HKD1_k127_7292051_28 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
HKD1_k127_7292051_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
HKD1_k127_7292051_3 Beta-lactamase K18372 - - 1.536e-212 664.0
HKD1_k127_7292051_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008214 243.0
HKD1_k127_7292051_31 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HKD1_k127_7292051_32 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000003684 245.0
HKD1_k127_7292051_33 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
HKD1_k127_7292051_34 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HKD1_k127_7292051_36 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000002075 200.0
HKD1_k127_7292051_37 bacterial (prokaryotic) histone like domain - - - 0.000000000000000000000000000000000000000000000006435 174.0
HKD1_k127_7292051_38 Protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000000000000006505 172.0
HKD1_k127_7292051_39 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000000000000004854 157.0
HKD1_k127_7292051_4 Luciferase-like monooxygenase - - - 1.042e-195 614.0
HKD1_k127_7292051_40 - - - - 0.0000000000000000000000000000000000000001451 162.0
HKD1_k127_7292051_41 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000006462 139.0
HKD1_k127_7292051_42 Putative peptidoglycan binding domain - - - 0.00006321 55.0
HKD1_k127_7292051_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 604.0
HKD1_k127_7292051_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 581.0
HKD1_k127_7292051_7 ABC transporter substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 569.0
HKD1_k127_7292051_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 537.0
HKD1_k127_7292051_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 536.0
HKD1_k127_7301722_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.098e-239 742.0
HKD1_k127_7301722_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 7.064e-226 707.0
HKD1_k127_7301722_2 PFAM amidohydrolase K07045 - - 3.098e-211 657.0
HKD1_k127_7301722_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 383.0
HKD1_k127_7350092_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2103.0
HKD1_k127_7350092_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.092e-260 816.0
HKD1_k127_7350092_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 399.0
HKD1_k127_7350092_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000591 271.0
HKD1_k127_7350092_4 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003688 223.0
HKD1_k127_7350092_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000001857 218.0
HKD1_k127_7350092_6 - - - - 0.000000000000000000000000000000003685 130.0
HKD1_k127_7350092_7 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.0000000000000000002699 93.0
HKD1_k127_7360700_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0 1028.0
HKD1_k127_7360700_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.003e-268 854.0
HKD1_k127_7360700_10 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 342.0
HKD1_k127_7360700_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 286.0
HKD1_k127_7360700_12 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 300.0
HKD1_k127_7360700_13 Protein of unknown function (DUF3035) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 276.0
HKD1_k127_7360700_14 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD1_k127_7360700_15 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000001962 183.0
HKD1_k127_7360700_17 Protein of unknown function (DUF433) - - - 0.0000000000000000000000001002 108.0
HKD1_k127_7360700_18 - - - - 0.00000000000000000000001569 105.0
HKD1_k127_7360700_2 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 2.595e-215 675.0
HKD1_k127_7360700_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 2.34e-204 643.0
HKD1_k127_7360700_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 5.28e-199 625.0
HKD1_k127_7360700_5 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 621.0
HKD1_k127_7360700_6 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 599.0
HKD1_k127_7360700_7 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 455.0
HKD1_k127_7360700_8 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 441.0
HKD1_k127_7360700_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 428.0
HKD1_k127_7422819_0 COG3264 Small-conductance mechanosensitive channel K05802 - - 4.084e-320 1004.0
HKD1_k127_7422819_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 1.268e-209 661.0
HKD1_k127_7422819_10 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
HKD1_k127_7422819_11 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000001333 234.0
HKD1_k127_7422819_12 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000003812 179.0
HKD1_k127_7422819_13 - - - - 0.00000000000000000000379 96.0
HKD1_k127_7422819_14 - - - - 0.00000000000000005249 82.0
HKD1_k127_7422819_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 7.892e-204 647.0
HKD1_k127_7422819_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 608.0
HKD1_k127_7422819_4 Alpha beta hydrolase K18092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 543.0
HKD1_k127_7422819_5 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 366.0
HKD1_k127_7422819_6 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 373.0
HKD1_k127_7422819_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 300.0
HKD1_k127_743563_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 575.0
HKD1_k127_743563_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 512.0
HKD1_k127_743563_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 424.0
HKD1_k127_743563_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
HKD1_k127_743563_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001553 257.0
HKD1_k127_743563_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003704 228.0
HKD1_k127_743563_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
HKD1_k127_743563_8 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0002896 45.0
HKD1_k127_7439180_0 Autotransporter beta-domain - - - 1.84e-234 768.0
HKD1_k127_7439180_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 579.0
HKD1_k127_7439180_10 GDP-mannose mannosyl hydrolase activity K01515,K03574,K12944 - 3.6.1.13,3.6.1.55 0.00000000000000000004929 98.0
HKD1_k127_7439180_2 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 488.0
HKD1_k127_7439180_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 475.0
HKD1_k127_7439180_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 450.0
HKD1_k127_7439180_5 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 436.0
HKD1_k127_7439180_6 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 424.0
HKD1_k127_7439180_7 Biotin-requiring enzyme K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
HKD1_k127_7439180_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001498 256.0
HKD1_k127_7439180_9 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000004717 120.0
HKD1_k127_7474732_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0 1211.0
HKD1_k127_7474732_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1079.0
HKD1_k127_7474732_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000005139 202.0
HKD1_k127_7474732_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 2.842e-253 787.0
HKD1_k127_7474732_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 9.087e-203 633.0
HKD1_k127_7474732_4 Dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 526.0
HKD1_k127_7474732_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 522.0
HKD1_k127_7474732_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 480.0
HKD1_k127_7474732_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 422.0
HKD1_k127_7474732_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 350.0
HKD1_k127_7502802_0 GMC oxidoreductase - - - 6.739e-282 872.0
HKD1_k127_7502802_1 FAD binding domain K00480 - 1.14.13.1 3.771e-199 629.0
HKD1_k127_7502802_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 345.0
HKD1_k127_7502802_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000792 261.0
HKD1_k127_7502802_4 - - - - 0.00000000000000000000000000000000000006242 147.0
HKD1_k127_7525531_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 5.849e-240 756.0
HKD1_k127_7525531_1 Phosphotransferase enzyme family - - - 7.471e-223 692.0
HKD1_k127_7525531_10 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 420.0
HKD1_k127_7525531_11 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 392.0
HKD1_k127_7525531_12 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 365.0
HKD1_k127_7525531_13 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000002737 250.0
HKD1_k127_7525531_15 NfeD-like C-terminal, partner-binding K07340 - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
HKD1_k127_7525531_16 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000002521 188.0
HKD1_k127_7525531_17 Alpha/beta hydrolase family - - - 0.000000000009138 73.0
HKD1_k127_7525531_18 - - - - 0.00000001065 68.0
HKD1_k127_7525531_2 COG0477 Permeases of the major facilitator superfamily - - - 9.238e-211 660.0
HKD1_k127_7525531_3 Acetamidase/Formamidase family - - - 1.24e-198 624.0
HKD1_k127_7525531_4 Permease MlaE K02066 - - 2.833e-195 623.0
HKD1_k127_7525531_5 MlaD protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 537.0
HKD1_k127_7525531_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 537.0
HKD1_k127_7525531_7 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 516.0
HKD1_k127_7525531_8 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 439.0
HKD1_k127_7525531_9 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 451.0
HKD1_k127_754385_0 Bacterial extracellular solute-binding protein K10108 - - 9.963e-224 700.0
HKD1_k127_754385_1 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 557.0
HKD1_k127_754385_2 Maltose transport system permease protein MalF P2 domain K10109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007041 262.0
HKD1_k127_754385_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000008059 60.0
HKD1_k127_7561672_0 - - - - 0.0 1088.0
HKD1_k127_7561672_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5.516e-289 894.0
HKD1_k127_7561672_10 - - - - 0.000000000001359 72.0
HKD1_k127_7561672_2 Sugar (and other) transporter - - - 4.286e-218 679.0
HKD1_k127_7561672_3 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 6.836e-218 680.0
HKD1_k127_7561672_4 Ketopantoate reductase PanE/ApbA C terminal - - - 1.039e-207 648.0
HKD1_k127_7561672_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 441.0
HKD1_k127_7561672_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
HKD1_k127_7561672_7 - - - - 0.000000000000000000000000000000000002261 149.0
HKD1_k127_7561672_8 Sugar (and other) transporter - - - 0.000000000000000000000000000005313 122.0
HKD1_k127_7561672_9 - - - - 0.000000000000000000001326 111.0
HKD1_k127_7563362_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.174e-266 824.0
HKD1_k127_7563362_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 484.0
HKD1_k127_7563362_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000000001507 171.0
HKD1_k127_7571244_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.3e-237 741.0
HKD1_k127_7571244_1 Zn-dependent protease, contains TPR repeats - - - 3.42e-221 693.0
HKD1_k127_7571244_10 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 391.0
HKD1_k127_7571244_11 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 362.0
HKD1_k127_7571244_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 388.0
HKD1_k127_7571244_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 286.0
HKD1_k127_7571244_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003409 263.0
HKD1_k127_7571244_15 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
HKD1_k127_7571244_16 - - - - 0.00000000000000000000000000000000000000000000000000000004192 198.0
HKD1_k127_7571244_17 - - - - 0.000000000000000005973 100.0
HKD1_k127_7571244_2 Aminotransferase - - - 2.167e-217 677.0
HKD1_k127_7571244_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 565.0
HKD1_k127_7571244_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 567.0
HKD1_k127_7571244_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 526.0
HKD1_k127_7571244_6 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 533.0
HKD1_k127_7571244_7 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 418.0
HKD1_k127_7571244_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 415.0
HKD1_k127_7584961_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 582.0
HKD1_k127_7584961_1 IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000000000000001424 145.0
HKD1_k127_7584961_2 Integrase - - - 0.000000000000000006066 86.0
HKD1_k127_7620662_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0 1294.0
HKD1_k127_7620662_1 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 1.557e-213 673.0
HKD1_k127_7620662_2 Polysaccharide deacetylase - - - 4.226e-199 620.0
HKD1_k127_7620662_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 541.0
HKD1_k127_7620662_4 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 283.0
HKD1_k127_7628488_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 3.405e-199 629.0
HKD1_k127_7628488_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000001466 70.0
HKD1_k127_7648693_0 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain K06147 - - 0.0 1110.0
HKD1_k127_7648693_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0 1014.0
HKD1_k127_7648693_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 448.0
HKD1_k127_7648693_11 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 447.0
HKD1_k127_7648693_12 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 438.0
HKD1_k127_7648693_13 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
HKD1_k127_7648693_14 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 378.0
HKD1_k127_7648693_15 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 341.0
HKD1_k127_7648693_16 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000111 239.0
HKD1_k127_7648693_17 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000002049 252.0
HKD1_k127_7648693_18 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000009864 216.0
HKD1_k127_7648693_19 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000199 214.0
HKD1_k127_7648693_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 7.37e-267 824.0
HKD1_k127_7648693_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000004152 211.0
HKD1_k127_7648693_21 Cytochrome C' - - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD1_k127_7648693_22 Belongs to the Fur family K03711 - - 0.000000000000002102 75.0
HKD1_k127_7648693_23 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000003625 54.0
HKD1_k127_7648693_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.511e-260 806.0
HKD1_k127_7648693_4 protein conserved in bacteria K09989 - - 9.36e-255 788.0
HKD1_k127_7648693_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 2.082e-244 765.0
HKD1_k127_7648693_6 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 573.0
HKD1_k127_7648693_7 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 538.0
HKD1_k127_7648693_8 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 511.0
HKD1_k127_7648693_9 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 486.0
HKD1_k127_7678314_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.26e-310 955.0
HKD1_k127_7678314_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.692e-306 946.0
HKD1_k127_7678314_10 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 356.0
HKD1_k127_7678314_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 346.0
HKD1_k127_7678314_12 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 311.0
HKD1_k127_7678314_13 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000017 230.0
HKD1_k127_7678314_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000002311 184.0
HKD1_k127_7678314_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 5.193e-223 695.0
HKD1_k127_7678314_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.895e-210 670.0
HKD1_k127_7678314_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 570.0
HKD1_k127_7678314_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 529.0
HKD1_k127_7678314_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 492.0
HKD1_k127_7678314_7 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 471.0
HKD1_k127_7678314_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 421.0
HKD1_k127_7678314_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 357.0
HKD1_k127_7679665_0 Enoyl-CoA hydratase/isomerase - - - 0.0 1028.0
HKD1_k127_7679665_1 benzoyl-CoA oxygenase - - - 3.107e-288 888.0
HKD1_k127_7679665_10 Transglutaminase - - - 2.551e-195 632.0
HKD1_k127_7679665_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 554.0
HKD1_k127_7679665_12 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 517.0
HKD1_k127_7679665_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 513.0
HKD1_k127_7679665_14 HIUase/Transthyretin family K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 484.0
HKD1_k127_7679665_15 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 470.0
HKD1_k127_7679665_16 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 469.0
HKD1_k127_7679665_17 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 467.0
HKD1_k127_7679665_18 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HKD1_k127_7679665_19 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 410.0
HKD1_k127_7679665_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.408e-286 891.0
HKD1_k127_7679665_20 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 323.0
HKD1_k127_7679665_21 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
HKD1_k127_7679665_22 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001785 295.0
HKD1_k127_7679665_23 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002715 281.0
HKD1_k127_7679665_24 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002002 226.0
HKD1_k127_7679665_25 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000006002 181.0
HKD1_k127_7679665_26 Protein of unknown function (DUF2971) - - - 0.000000000000000000000000004946 123.0
HKD1_k127_7679665_28 - - - - 0.0000000000000009291 84.0
HKD1_k127_7679665_29 Cupin - - - 0.0001036 50.0
HKD1_k127_7679665_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 6.13e-286 885.0
HKD1_k127_7679665_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 5.792e-258 808.0
HKD1_k127_7679665_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.868e-236 739.0
HKD1_k127_7679665_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.141e-222 700.0
HKD1_k127_7679665_7 Adenylate cyclase K01768 - 4.6.1.1 2.545e-211 667.0
HKD1_k127_7679665_8 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 9.801e-200 625.0
HKD1_k127_7679665_9 Adenylate cyclase K01768 - 4.6.1.1 1.057e-199 653.0
HKD1_k127_7727885_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 487.0
HKD1_k127_7727885_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004201 221.0
HKD1_k127_7727885_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000001719 173.0
HKD1_k127_7727885_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001577 149.0
HKD1_k127_7730755_0 Luciferase-like monooxygenase K09018 - 1.14.99.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 545.0
HKD1_k127_7730755_1 Luciferase-like monooxygenase K09018 - 1.14.99.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 531.0
HKD1_k127_7730755_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 474.0
HKD1_k127_7730755_3 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 476.0
HKD1_k127_7730755_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 380.0
HKD1_k127_7730755_5 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 334.0
HKD1_k127_7730755_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 299.0
HKD1_k127_7730755_8 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000001002 124.0
HKD1_k127_7730755_9 PFAM FAD linked oxidase domain protein - - - 0.00000000000001631 77.0
HKD1_k127_7731263_0 Receptor family ligand binding region - - - 2.809e-224 699.0
HKD1_k127_7731263_1 HI0933-like protein K07007 - - 2.456e-206 656.0
HKD1_k127_7731263_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 561.0
HKD1_k127_7731263_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 499.0
HKD1_k127_7731263_4 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 428.0
HKD1_k127_7731263_5 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 391.0
HKD1_k127_7731263_6 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001067 263.0
HKD1_k127_7731263_7 Belongs to the ABC transporter superfamily K01996 GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
HKD1_k127_7744605_0 metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 569.0
HKD1_k127_7744605_1 Phosphonate ABC transporter K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 511.0
HKD1_k127_7744605_10 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 - 2.7.4.23 0.00000000000000000000000000000000000000000002748 171.0
HKD1_k127_7744605_11 Sodium Bile acid symporter family - - - 0.00000001058 66.0
HKD1_k127_7744605_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 450.0
HKD1_k127_7744605_3 Phosphonate ABC transporter K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 444.0
HKD1_k127_7744605_4 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 403.0
HKD1_k127_7744605_5 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 406.0
HKD1_k127_7744605_6 Protein of unknown function (DUF1045) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 353.0
HKD1_k127_7744605_7 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001115 217.0
HKD1_k127_7744605_8 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000000000000000000000000000000007589 195.0
HKD1_k127_7744605_9 - - - - 0.00000000000000000000000000000000000000000000000005177 196.0
HKD1_k127_7790789_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1146.0
HKD1_k127_7790789_1 COG0457 FOG TPR repeat - - - 6.724e-259 803.0
HKD1_k127_7790789_10 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 490.0
HKD1_k127_7790789_11 Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP K00868 - 2.7.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 469.0
HKD1_k127_7790789_12 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 398.0
HKD1_k127_7790789_13 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 323.0
HKD1_k127_7790789_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002648 273.0
HKD1_k127_7790789_15 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002987 272.0
HKD1_k127_7790789_16 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000000000000000000000000000000001149 201.0
HKD1_k127_7790789_17 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000001942 182.0
HKD1_k127_7790789_2 carnitine dehydratase K07749 - 2.8.3.16 2.132e-219 684.0
HKD1_k127_7790789_3 COG2030 Acyl dehydratase K14449 - 4.2.1.148 9.058e-205 641.0
HKD1_k127_7790789_4 general L-amino acid-binding periplasmic protein AapJ K09969 - - 8.638e-200 626.0
HKD1_k127_7790789_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.059e-199 624.0
HKD1_k127_7790789_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 544.0
HKD1_k127_7790789_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 515.0
HKD1_k127_7790789_8 carnitine dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 489.0
HKD1_k127_7790789_9 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 478.0
HKD1_k127_7882655_0 TAP-like protein - - - 5.185e-271 846.0
HKD1_k127_7882655_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.889e-257 795.0
HKD1_k127_7882655_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 422.0
HKD1_k127_7882655_11 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
HKD1_k127_7882655_12 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 407.0
HKD1_k127_7882655_13 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 373.0
HKD1_k127_7882655_14 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 302.0
HKD1_k127_7882655_15 protein conserved in bacteria K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 291.0
HKD1_k127_7882655_16 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002885 276.0
HKD1_k127_7882655_17 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001352 247.0
HKD1_k127_7882655_18 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000000000000000000000000002516 173.0
HKD1_k127_7882655_19 NADH-ubiquinone oxidoreductase chain 49kDa - - - 0.0000000000000000000000004377 121.0
HKD1_k127_7882655_2 Proton-conducting membrane transporter - - - 1.116e-253 799.0
HKD1_k127_7882655_3 Major Facilitator Superfamily - - - 5.379e-241 749.0
HKD1_k127_7882655_4 COG0665 Glycine D-amino acid oxidases (deaminating) K00285,K21060 - 1.4.5.1 1.547e-228 711.0
HKD1_k127_7882655_5 Aminotransferase class-V - - - 5.313e-210 657.0
HKD1_k127_7882655_6 Proton-conducting membrane transporter K12141 - - 1.705e-206 655.0
HKD1_k127_7882655_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 1.512e-196 616.0
HKD1_k127_7882655_8 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 536.0
HKD1_k127_7882655_9 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 458.0
HKD1_k127_7895649_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 - 4.2.1.46,4.2.1.76 4.704e-212 662.0
HKD1_k127_7895649_1 Belongs to the DegT DnrJ EryC1 family - - - 2.416e-202 635.0
HKD1_k127_7895649_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 372.0
HKD1_k127_7895649_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
HKD1_k127_7895649_12 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 310.0
HKD1_k127_7895649_13 WxcM-like, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000001372 215.0
HKD1_k127_7895649_14 enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000005076 198.0
HKD1_k127_7895649_15 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000715 186.0
HKD1_k127_7895649_17 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000001549 110.0
HKD1_k127_7895649_2 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 602.0
HKD1_k127_7895649_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 567.0
HKD1_k127_7895649_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 499.0
HKD1_k127_7895649_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 488.0
HKD1_k127_7895649_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 481.0
HKD1_k127_7895649_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 468.0
HKD1_k127_7895649_8 acid transport K09972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 391.0
HKD1_k127_7895649_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 403.0
HKD1_k127_7910751_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1624.0
HKD1_k127_7910751_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 5.474e-321 987.0
HKD1_k127_7910751_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
HKD1_k127_7910751_11 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 396.0
HKD1_k127_7910751_12 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 389.0
HKD1_k127_7910751_13 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 383.0
HKD1_k127_7910751_14 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
HKD1_k127_7910751_15 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 341.0
HKD1_k127_7910751_16 Flavin reductase like domain K09024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 312.0
HKD1_k127_7910751_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000001611 240.0
HKD1_k127_7910751_18 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000001797 240.0
HKD1_k127_7910751_2 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 1.009e-309 958.0
HKD1_k127_7910751_21 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000001396 126.0
HKD1_k127_7910751_23 - - - - 0.000001426 51.0
HKD1_k127_7910751_24 - - - - 0.000004271 59.0
HKD1_k127_7910751_25 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.00002606 52.0
HKD1_k127_7910751_3 Adenylate cyclase - - - 1.877e-308 954.0
HKD1_k127_7910751_4 cobalamin synthesis protein - - - 2.863e-223 695.0
HKD1_k127_7910751_5 Aconitase family (aconitate hydratase) - - - 8.075e-219 688.0
HKD1_k127_7910751_6 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 539.0
HKD1_k127_7910751_7 Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 483.0
HKD1_k127_7910751_8 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 437.0
HKD1_k127_7910751_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 426.0
HKD1_k127_7912015_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 590.0
HKD1_k127_7912015_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 419.0
HKD1_k127_7912015_2 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000006704 199.0
HKD1_k127_7912015_3 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.000000000000000000889 87.0
HKD1_k127_791268_0 beta (1-6) glucans synthase - - - 0.0 1135.0
HKD1_k127_791268_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1120.0
HKD1_k127_791268_10 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 363.0
HKD1_k127_791268_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
HKD1_k127_791268_12 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
HKD1_k127_791268_13 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
HKD1_k127_791268_14 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
HKD1_k127_791268_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001617 256.0
HKD1_k127_791268_2 Protein of unknown function (DUF2817) - - - 1.052e-218 681.0
HKD1_k127_791268_3 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 1.846e-199 622.0
HKD1_k127_791268_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 506.0
HKD1_k127_791268_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 497.0
HKD1_k127_791268_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 465.0
HKD1_k127_791268_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 456.0
HKD1_k127_791268_8 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 403.0
HKD1_k127_791268_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 366.0
HKD1_k127_792272_0 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.0 1049.0
HKD1_k127_792272_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.0 998.0
HKD1_k127_792272_2 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
HKD1_k127_792272_3 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 546.0
HKD1_k127_792272_4 KR domain K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 495.0
HKD1_k127_792272_5 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 327.0
HKD1_k127_792272_6 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 316.0
HKD1_k127_792272_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005761 251.0
HKD1_k127_792272_8 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003642 267.0
HKD1_k127_792272_9 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000002713 171.0
HKD1_k127_7963880_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.296e-270 841.0
HKD1_k127_7963880_1 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 599.0
HKD1_k127_7963880_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 585.0
HKD1_k127_7963880_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 538.0
HKD1_k127_7963880_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 509.0
HKD1_k127_7963880_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 457.0
HKD1_k127_7963880_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000203 217.0
HKD1_k127_7972382_0 Histidine kinase-like ATPases - - - 0.0 1090.0
HKD1_k127_7972382_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 450.0
HKD1_k127_7972382_2 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 322.0
HKD1_k127_7972382_3 Cupin superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002976 297.0
HKD1_k127_7972382_4 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000000000001967 191.0
HKD1_k127_7972382_5 ABC transporter substrate binding protein K01989 - - 0.000000000000935 71.0
HKD1_k127_7972382_6 FR47-like protein - - - 0.00000001557 57.0
HKD1_k127_79914_0 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 380.0
HKD1_k127_79914_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000005461 102.0
HKD1_k127_79914_2 Winged helix DNA-binding domain - - - 0.0000000000000001559 93.0
HKD1_k127_8006537_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.789e-224 700.0
HKD1_k127_8006537_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 8.813e-214 673.0
HKD1_k127_8006537_10 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 448.0
HKD1_k127_8006537_11 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 403.0
HKD1_k127_8006537_12 methionine biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 381.0
HKD1_k127_8006537_13 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
HKD1_k127_8006537_14 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 333.0
HKD1_k127_8006537_15 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 331.0
HKD1_k127_8006537_16 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 291.0
HKD1_k127_8006537_17 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006271 293.0
HKD1_k127_8006537_18 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
HKD1_k127_8006537_19 universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003879 263.0
HKD1_k127_8006537_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 3.367e-209 655.0
HKD1_k127_8006537_20 transcriptional regulator K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005817 259.0
HKD1_k127_8006537_21 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002735 240.0
HKD1_k127_8006537_22 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000008183 242.0
HKD1_k127_8006537_23 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000001525 197.0
HKD1_k127_8006537_24 ybak prolyl-trna synthetase associated K19055 - - 0.000000000000000000000000000000000001161 144.0
HKD1_k127_8006537_25 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000006247 119.0
HKD1_k127_8006537_26 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000002976 126.0
HKD1_k127_8006537_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 606.0
HKD1_k127_8006537_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 593.0
HKD1_k127_8006537_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 522.0
HKD1_k127_8006537_6 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
HKD1_k127_8006537_7 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 486.0
HKD1_k127_8006537_8 chorismate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 464.0
HKD1_k127_8006537_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 456.0
HKD1_k127_802213_0 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.0 1171.0
HKD1_k127_802213_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1157.0
HKD1_k127_802213_10 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 428.0
HKD1_k127_802213_11 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 415.0
HKD1_k127_802213_12 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 387.0
HKD1_k127_802213_13 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 353.0
HKD1_k127_802213_14 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 297.0
HKD1_k127_802213_15 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 299.0
HKD1_k127_802213_16 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002348 263.0
HKD1_k127_802213_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001697 244.0
HKD1_k127_802213_18 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002396 250.0
HKD1_k127_802213_19 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003873 247.0
HKD1_k127_802213_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.798e-303 932.0
HKD1_k127_802213_20 FixH - - - 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
HKD1_k127_802213_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000004763 219.0
HKD1_k127_802213_22 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000007784 199.0
HKD1_k127_802213_23 'PFAM Response regulator receiver - - - 0.0000000000000000000000000000000000000002157 153.0
HKD1_k127_802213_24 - - - - 0.000000000000000000002495 108.0
HKD1_k127_802213_28 cytochrome oxidase maturation protein - - - 0.00000000000001539 87.0
HKD1_k127_802213_3 Nitrogen fixation protein fixG - - - 4.042e-262 812.0
HKD1_k127_802213_4 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 4.134e-240 759.0
HKD1_k127_802213_5 His Kinase A (phosphoacceptor) domain - - - 3.705e-201 649.0
HKD1_k127_802213_6 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 558.0
HKD1_k127_802213_7 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 517.0
HKD1_k127_802213_8 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 522.0
HKD1_k127_802213_9 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 444.0
HKD1_k127_8023080_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1452.0
HKD1_k127_8023080_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 2.034e-320 988.0
HKD1_k127_8023080_10 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 572.0
HKD1_k127_8023080_11 Aconitase family (aconitate hydratase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 520.0
HKD1_k127_8023080_12 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 511.0
HKD1_k127_8023080_13 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 490.0
HKD1_k127_8023080_14 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 480.0
HKD1_k127_8023080_15 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 489.0
HKD1_k127_8023080_16 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 453.0
HKD1_k127_8023080_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 477.0
HKD1_k127_8023080_18 Aconitase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 370.0
HKD1_k127_8023080_19 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
HKD1_k127_8023080_2 Major Facilitator Superfamily K03446 - - 1.335e-297 917.0
HKD1_k127_8023080_21 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004262 253.0
HKD1_k127_8023080_22 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004121 247.0
HKD1_k127_8023080_23 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005544 252.0
HKD1_k127_8023080_24 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 241.0
HKD1_k127_8023080_26 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000377 130.0
HKD1_k127_8023080_27 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000006224 125.0
HKD1_k127_8023080_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.455e-292 902.0
HKD1_k127_8023080_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.592e-277 861.0
HKD1_k127_8023080_5 Peptidase dimerisation domain K01438 - 3.5.1.16 1.211e-274 846.0
HKD1_k127_8023080_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.588e-217 677.0
HKD1_k127_8023080_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 4.257e-205 643.0
HKD1_k127_8023080_8 peptidyl-tyrosine sulfation - - - 2.89e-196 621.0
HKD1_k127_8023080_9 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 574.0
HKD1_k127_811946_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0 1236.0
HKD1_k127_811946_1 SbmA/BacA-like family K02471 - - 0.0 1012.0
HKD1_k127_811946_10 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 376.0
HKD1_k127_811946_11 transcriptional regulator K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 293.0
HKD1_k127_811946_12 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002459 263.0
HKD1_k127_811946_13 sulfur oxidation protein (SoxY) K17226 - - 0.000000000000000000000000000000000000000000000000000000005123 201.0
HKD1_k127_811946_14 cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000004898 211.0
HKD1_k127_811946_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002919 185.0
HKD1_k127_811946_16 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000001604 162.0
HKD1_k127_811946_17 Ion channel - - - 0.00000000000000000000000000000000000009275 149.0
HKD1_k127_811946_19 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000001006 115.0
HKD1_k127_811946_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 6.155e-305 940.0
HKD1_k127_811946_20 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000271 117.0
HKD1_k127_811946_22 Integrase core domain - - - 0.0008282 42.0
HKD1_k127_811946_3 Belongs to the TPP enzyme family K01576 - 4.1.1.7 2.019e-283 878.0
HKD1_k127_811946_4 COG1960 Acyl-CoA dehydrogenases - - - 8.773e-244 758.0
HKD1_k127_811946_5 Sulfide dehydrogenase - - - 1.684e-222 694.0
HKD1_k127_811946_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 518.0
HKD1_k127_811946_7 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 467.0
HKD1_k127_811946_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 406.0
HKD1_k127_811946_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 395.0
HKD1_k127_818250_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 461.0
HKD1_k127_818250_1 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 448.0
HKD1_k127_854595_0 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 404.0
HKD1_k127_854595_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
HKD1_k127_854595_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000002084 61.0
HKD1_k127_858146_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.127e-224 696.0
HKD1_k127_858146_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 1.629e-195 613.0
HKD1_k127_858146_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 552.0
HKD1_k127_858146_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 423.0
HKD1_k127_858146_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 385.0
HKD1_k127_858146_5 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HKD1_k127_858146_6 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000143 243.0
HKD1_k127_898132_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family - - - 0.0 1585.0
HKD1_k127_898132_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5e-323 992.0
HKD1_k127_898132_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 487.0
HKD1_k127_898132_11 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 423.0
HKD1_k127_898132_12 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001582 283.0
HKD1_k127_898132_13 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002132 265.0
HKD1_k127_898132_14 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000001007 68.0
HKD1_k127_898132_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.009e-273 848.0
HKD1_k127_898132_3 Periplasmic binding protein domain - - - 3.189e-228 732.0
HKD1_k127_898132_4 PFAM Acyl-CoA dehydrogenase type 2 K16047 - 1.14.14.12 1.838e-199 655.0
HKD1_k127_898132_5 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 568.0
HKD1_k127_898132_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 560.0
HKD1_k127_898132_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 543.0
HKD1_k127_898132_8 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 541.0
HKD1_k127_898132_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 486.0
HKD1_k127_919643_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 4.467e-314 967.0
HKD1_k127_919643_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.951e-260 812.0
HKD1_k127_919643_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000006735 225.0
HKD1_k127_919643_11 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000131 126.0
HKD1_k127_919643_12 FecR protein - - - 0.00000000000000000000004131 113.0
HKD1_k127_919643_13 - - - - 0.000000000000000000003945 99.0
HKD1_k127_919643_14 Tetratricopeptide repeat - - - 0.0000000000000004115 85.0
HKD1_k127_919643_15 Glutathione S-transferase, C-terminal domain - - - 0.0000000001089 66.0
HKD1_k127_919643_2 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 8.57e-241 781.0
HKD1_k127_919643_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 557.0
HKD1_k127_919643_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 430.0
HKD1_k127_919643_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 415.0
HKD1_k127_919643_6 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 381.0
HKD1_k127_919643_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 378.0
HKD1_k127_919643_8 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 350.0
HKD1_k127_919643_9 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 308.0
HKD1_k127_930989_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1163.0
HKD1_k127_930989_1 Binding-protein-dependent transport system inner membrane component - - - 4.703e-314 968.0
HKD1_k127_930989_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.985e-208 660.0
HKD1_k127_930989_11 Receptor family ligand binding region - - - 5.782e-202 637.0
HKD1_k127_930989_12 - - - - 4.703e-195 620.0
HKD1_k127_930989_13 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 608.0
HKD1_k127_930989_14 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 565.0
HKD1_k127_930989_15 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 594.0
HKD1_k127_930989_16 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 564.0
HKD1_k127_930989_17 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 542.0
HKD1_k127_930989_18 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 525.0
HKD1_k127_930989_19 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 515.0
HKD1_k127_930989_2 Sulfatase K01133 - 3.1.6.6 1.426e-307 950.0
HKD1_k127_930989_20 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 510.0
HKD1_k127_930989_21 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 499.0
HKD1_k127_930989_22 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 475.0
HKD1_k127_930989_23 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 451.0
HKD1_k127_930989_24 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 414.0
HKD1_k127_930989_25 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 316.0
HKD1_k127_930989_26 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
HKD1_k127_930989_27 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 294.0
HKD1_k127_930989_28 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 301.0
HKD1_k127_930989_29 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
HKD1_k127_930989_3 Major Facilitator Superfamily - - - 1.005e-276 856.0
HKD1_k127_930989_30 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006016 262.0
HKD1_k127_930989_31 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007477 265.0
HKD1_k127_930989_32 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001275 239.0
HKD1_k127_930989_33 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001755 235.0
HKD1_k127_930989_34 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000004907 188.0
HKD1_k127_930989_35 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000001538 174.0
HKD1_k127_930989_36 - - - - 0.0000000000000000000000005996 121.0
HKD1_k127_930989_4 MmgE/PrpD family - - - 3.49e-252 782.0
HKD1_k127_930989_5 III protein, CoA-transferase family - - - 2.112e-242 750.0
HKD1_k127_930989_6 III protein, CoA-transferase family - - - 8.206e-233 724.0
HKD1_k127_930989_7 COG1960 Acyl-CoA dehydrogenases - - - 4.199e-230 715.0
HKD1_k127_930989_8 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 6.398e-217 681.0
HKD1_k127_930989_9 Periplasmic binding protein K01999 - - 5.499e-215 676.0
HKD1_k127_936307_0 phosphonate metabolism K06164 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 610.0
HKD1_k127_936307_1 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 - 4.7.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 534.0
HKD1_k127_936307_2 (ABC transporter), ATP-binding K05780 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 365.0
HKD1_k127_936307_3 ABC transporter K05781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 374.0
HKD1_k127_936307_4 metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 321.0
HKD1_k127_936307_5 Bacterial phosphonate metabolism protein (PhnH) K06165 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000000001104 248.0
HKD1_k127_936307_6 Phosphonate C-P lyase system protein PhnG K06166 - 2.7.8.37 0.000000000000000000000000000000000000009513 149.0
HKD1_k127_956629_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1833.0
HKD1_k127_956629_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1454.0
HKD1_k127_956629_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
HKD1_k127_956629_11 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000001104 213.0
HKD1_k127_956629_12 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000001917 171.0
HKD1_k127_956629_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000001822 114.0
HKD1_k127_956629_15 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000002953 96.0
HKD1_k127_956629_2 phosphomannomutase K01840 - 5.4.2.8 1.179e-276 854.0
HKD1_k127_956629_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.756e-258 799.0
HKD1_k127_956629_4 Peptidogalycan biosysnthesis/recognition K09919 - - 2.026e-243 753.0
HKD1_k127_956629_5 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 573.0
HKD1_k127_956629_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 551.0
HKD1_k127_956629_7 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 499.0
HKD1_k127_956629_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 354.0
HKD1_k127_956629_9 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 350.0
HKD1_k127_965162_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1693.0
HKD1_k127_965162_1 Amidohydrolase family - - - 0.0 1022.0
HKD1_k127_965162_2 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 7.87e-228 726.0
HKD1_k127_965162_3 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 590.0
HKD1_k127_965162_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 546.0
HKD1_k127_965162_5 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 372.0
HKD1_k127_965162_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
HKD1_k127_965162_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000003152 205.0
HKD1_k127_965162_8 Belongs to the 'phage' integrase family - - - 0.0000001686 54.0
HKD1_k127_986220_0 Cysteine-rich domain - - - 7.357e-272 839.0
HKD1_k127_986220_1 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 1.54e-232 724.0
HKD1_k127_986220_10 energy transducer activity K03832 - - 0.00000000000000000000000000000000000001011 156.0
HKD1_k127_986220_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 482.0
HKD1_k127_986220_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 334.0
HKD1_k127_986220_4 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 331.0
HKD1_k127_986220_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 329.0
HKD1_k127_986220_6 COG1592 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000134 279.0
HKD1_k127_986220_7 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
HKD1_k127_986220_8 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
HKD1_k127_986220_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000002632 168.0
HKD1_k127_986647_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 4.593e-222 702.0
HKD1_k127_986647_1 - K03571 - - 0.0000000000000000000000000000000004862 134.0