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Overview

ID MAG01734
Name HKD1_bin.51
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfobaccia
Order Desulfobaccales
Family 0-14-0-80-60-11
Genus 0-14-0-80-60-11
Species
Assembly information
Completeness (%) 98.03
Contamination (%) 0.96
GC content (%) 61.0
N50 (bp) 25,823
Genome size (bp) 3,079,809

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2775

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_114392_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1235.0
HKD1_k127_114392_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.282e-301 939.0
HKD1_k127_114392_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 339.0
HKD1_k127_114392_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 308.0
HKD1_k127_114392_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
HKD1_k127_114392_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
HKD1_k127_114392_14 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000005467 190.0
HKD1_k127_114392_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001691 183.0
HKD1_k127_114392_16 - - - - 0.000000000000000000000000000000000000000000000002884 174.0
HKD1_k127_114392_17 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000000000000000000000000000000000000006382 171.0
HKD1_k127_114392_2 Translation-initiation factor 2 K02519 - - 5.351e-228 737.0
HKD1_k127_114392_20 RimP C-terminal SH3 domain K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000005771 156.0
HKD1_k127_114392_21 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001147 151.0
HKD1_k127_114392_22 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000727 143.0
HKD1_k127_114392_24 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000001428 126.0
HKD1_k127_114392_25 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000002471 119.0
HKD1_k127_114392_26 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.000000000000000000000000001232 116.0
HKD1_k127_114392_28 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000009512 78.0
HKD1_k127_114392_29 Protein of unknown function DUF86 - - - 0.00000000001838 64.0
HKD1_k127_114392_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.886e-224 701.0
HKD1_k127_114392_30 Protein of unknown function DUF86 K07075 - - 0.0000000005847 61.0
HKD1_k127_114392_4 PFAM Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 1.737e-204 645.0
HKD1_k127_114392_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 603.0
HKD1_k127_114392_6 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 600.0
HKD1_k127_114392_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 449.0
HKD1_k127_114392_8 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 443.0
HKD1_k127_114392_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 374.0
HKD1_k127_1328076_0 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000000000000000001037 145.0
HKD1_k127_1328076_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000005726 147.0
HKD1_k127_1328076_2 Polysulphide reductase, NrfD K00185 - - 0.0000000003111 64.0
HKD1_k127_1328076_3 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000001068 64.0
HKD1_k127_1468309_0 Carbamoyltransferase C-terminus K00612 - - 2.648e-307 951.0
HKD1_k127_1468309_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.989e-298 957.0
HKD1_k127_1468309_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 404.0
HKD1_k127_1468309_12 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 402.0
HKD1_k127_1468309_13 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 366.0
HKD1_k127_1468309_14 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
HKD1_k127_1468309_15 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HKD1_k127_1468309_16 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
HKD1_k127_1468309_17 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 348.0
HKD1_k127_1468309_18 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 338.0
HKD1_k127_1468309_19 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HKD1_k127_1468309_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.333e-202 644.0
HKD1_k127_1468309_20 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 297.0
HKD1_k127_1468309_21 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
HKD1_k127_1468309_22 -O-antigen K02847,K13009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009894 269.0
HKD1_k127_1468309_23 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002087 259.0
HKD1_k127_1468309_24 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000006505 194.0
HKD1_k127_1468309_25 - - - - 0.0000000000000000000000000586 113.0
HKD1_k127_1468309_26 - - - - 0.0000000000000000006671 86.0
HKD1_k127_1468309_27 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.0000000000007446 80.0
HKD1_k127_1468309_28 - - - - 0.0000001478 62.0
HKD1_k127_1468309_3 aminotransferase, class I and II K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 605.0
HKD1_k127_1468309_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 580.0
HKD1_k127_1468309_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 570.0
HKD1_k127_1468309_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 524.0
HKD1_k127_1468309_7 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 455.0
HKD1_k127_1468309_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 443.0
HKD1_k127_1468309_9 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 455.0
HKD1_k127_1494466_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1044.0
HKD1_k127_1494466_1 ABC-type multidrug transport system ATPase and permease K06147 - - 1.36e-199 638.0
HKD1_k127_1494466_10 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 287.0
HKD1_k127_1494466_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002149 261.0
HKD1_k127_1494466_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
HKD1_k127_1494466_13 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007053 262.0
HKD1_k127_1494466_14 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000004432 228.0
HKD1_k127_1494466_15 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000001015 206.0
HKD1_k127_1494466_16 Histidine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000005978 213.0
HKD1_k127_1494466_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000003264 158.0
HKD1_k127_1494466_18 Ferric uptake regulator family K03711 - - 0.00000000000000000003115 98.0
HKD1_k127_1494466_19 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000005864 91.0
HKD1_k127_1494466_2 Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 620.0
HKD1_k127_1494466_20 3D domain protein - - - 0.00009713 50.0
HKD1_k127_1494466_21 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0006693 43.0
HKD1_k127_1494466_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 511.0
HKD1_k127_1494466_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 467.0
HKD1_k127_1494466_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 423.0
HKD1_k127_1494466_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
HKD1_k127_1494466_7 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 370.0
HKD1_k127_1494466_8 PFAM periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 370.0
HKD1_k127_1494466_9 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 331.0
HKD1_k127_1508919_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 582.0
HKD1_k127_1508919_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 577.0
HKD1_k127_1508919_2 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HKD1_k127_1508919_3 cytolysis by virus of host cell K01185 - 3.2.1.17 0.00000000000000000000000000000000000000000003924 168.0
HKD1_k127_1508919_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000001051 96.0
HKD1_k127_150960_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 519.0
HKD1_k127_150960_1 PFAM Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 511.0
HKD1_k127_150960_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007305 226.0
HKD1_k127_150960_3 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000009404 180.0
HKD1_k127_1520296_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.511e-208 659.0
HKD1_k127_1520296_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000004374 66.0
HKD1_k127_1520613_0 Signal transduction histidine kinase - - - 7.05e-278 873.0
HKD1_k127_1520613_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.739e-275 857.0
HKD1_k127_1520613_10 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HKD1_k127_1520613_11 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009953 266.0
HKD1_k127_1520613_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000005319 237.0
HKD1_k127_1520613_13 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001102 235.0
HKD1_k127_1520613_14 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000000000000006193 228.0
HKD1_k127_1520613_15 Protein of unknown function (DUF1641) - - - 0.0000000000000000000000000000000000000000000000000000000000000003801 232.0
HKD1_k127_1520613_16 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000008429 226.0
HKD1_k127_1520613_17 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000000002453 224.0
HKD1_k127_1520613_18 COGs COG0794 sugar phosphate isomerase involved in capsule formation K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000001235 193.0
HKD1_k127_1520613_19 uracil-dna glycosylase - - - 0.00000000000000000000000000000000000000000002051 175.0
HKD1_k127_1520613_2 Belongs to the RtcB family K14415 - 6.5.1.3 3.225e-238 743.0
HKD1_k127_1520613_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000444 151.0
HKD1_k127_1520613_21 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000000000000000000000000000000531 147.0
HKD1_k127_1520613_22 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000006654 148.0
HKD1_k127_1520613_23 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000002631 142.0
HKD1_k127_1520613_24 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000004542 138.0
HKD1_k127_1520613_25 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001553 109.0
HKD1_k127_1520613_26 23S rRNA-intervening sequence protein - - - 0.000000000000000000001403 96.0
HKD1_k127_1520613_27 Belongs to the UPF0109 family K06960 - - 0.0000000000000000001845 90.0
HKD1_k127_1520613_28 PFAM ROSMUCR transcriptional regulator - - - 0.00001102 51.0
HKD1_k127_1520613_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.109e-216 680.0
HKD1_k127_1520613_4 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 3.025e-211 667.0
HKD1_k127_1520613_5 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 1.898e-210 660.0
HKD1_k127_1520613_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.237e-201 635.0
HKD1_k127_1520613_7 Orotidine 5'-phosphate decarboxylase / HUMPS family K13831 - 4.1.2.43,5.3.1.27 6.67e-201 633.0
HKD1_k127_1520613_8 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 349.0
HKD1_k127_1520613_9 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HKD1_k127_1520706_0 PFAM 4Fe-4S binding domain - - - 8.105e-218 686.0
HKD1_k127_1520706_1 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 606.0
HKD1_k127_1520706_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 548.0
HKD1_k127_1520706_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 469.0
HKD1_k127_1520706_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 444.0
HKD1_k127_1520706_5 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001251 266.0
HKD1_k127_1520706_6 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000002333 81.0
HKD1_k127_1521107_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1225.0
HKD1_k127_1521107_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.814e-245 769.0
HKD1_k127_1521107_10 HlyD family secretion protein K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 429.0
HKD1_k127_1521107_11 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 411.0
HKD1_k127_1521107_12 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 409.0
HKD1_k127_1521107_13 PFAM Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 392.0
HKD1_k127_1521107_14 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
HKD1_k127_1521107_15 Phospholipase D. Active site motifs. K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 381.0
HKD1_k127_1521107_16 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
HKD1_k127_1521107_17 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
HKD1_k127_1521107_18 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 307.0
HKD1_k127_1521107_19 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008301 248.0
HKD1_k127_1521107_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.609e-202 638.0
HKD1_k127_1521107_20 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003547 249.0
HKD1_k127_1521107_21 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000006977 233.0
HKD1_k127_1521107_22 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000006044 235.0
HKD1_k127_1521107_23 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000001611 229.0
HKD1_k127_1521107_24 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
HKD1_k127_1521107_25 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
HKD1_k127_1521107_26 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
HKD1_k127_1521107_27 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
HKD1_k127_1521107_28 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000002627 212.0
HKD1_k127_1521107_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 532.0
HKD1_k127_1521107_30 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000002864 194.0
HKD1_k127_1521107_32 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000002089 128.0
HKD1_k127_1521107_33 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001295 127.0
HKD1_k127_1521107_34 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000001256 111.0
HKD1_k127_1521107_35 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000001076 103.0
HKD1_k127_1521107_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 518.0
HKD1_k127_1521107_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 512.0
HKD1_k127_1521107_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 505.0
HKD1_k127_1521107_7 Coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 507.0
HKD1_k127_1521107_8 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 505.0
HKD1_k127_1521107_9 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 452.0
HKD1_k127_1521113_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.092e-201 636.0
HKD1_k127_1521113_1 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 509.0
HKD1_k127_1521113_10 Methyltransferase domain K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000004519 185.0
HKD1_k127_1521113_11 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000001378 136.0
HKD1_k127_1521113_12 - - - - 0.00000000000000000000001024 104.0
HKD1_k127_1521113_13 HD domain - - - 0.00000000000000000005139 102.0
HKD1_k127_1521113_14 - - - - 0.0000000000006027 71.0
HKD1_k127_1521113_2 DNA segregation ATPase, FtsK SpoIIIE family K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 520.0
HKD1_k127_1521113_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 389.0
HKD1_k127_1521113_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 358.0
HKD1_k127_1521113_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 341.0
HKD1_k127_1521113_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
HKD1_k127_1521113_7 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 301.0
HKD1_k127_1521113_8 AAA domain K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 294.0
HKD1_k127_1521113_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
HKD1_k127_1521409_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1099.0
HKD1_k127_1521409_1 TIGRFAM Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 6.679e-314 966.0
HKD1_k127_1521409_10 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 409.0
HKD1_k127_1521409_11 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 409.0
HKD1_k127_1521409_12 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 357.0
HKD1_k127_1521409_13 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD1_k127_1521409_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004801 276.0
HKD1_k127_1521409_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HKD1_k127_1521409_16 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007815 253.0
HKD1_k127_1521409_17 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
HKD1_k127_1521409_18 Belongs to the P(II) protein family K02590 - - 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
HKD1_k127_1521409_19 RNB K12573 - - 0.0000000000000000000000000000000000000000000000000000000000003885 216.0
HKD1_k127_1521409_2 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 7.036e-259 803.0
HKD1_k127_1521409_20 Belongs to the P(II) protein family K02589 - - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD1_k127_1521409_21 Ferredoxin - - - 0.000000000000000000000000000000000000000000000043 170.0
HKD1_k127_1521409_22 NhaP-type Na H and K H - - - 0.000000000000000000000000000000000000000000004704 164.0
HKD1_k127_1521409_23 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000000002309 124.0
HKD1_k127_1521409_24 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000001878 118.0
HKD1_k127_1521409_25 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000004566 92.0
HKD1_k127_1521409_26 ISXO2-like transposase domain - - - 0.00000000000006281 72.0
HKD1_k127_1521409_27 Carbon-nitrogen hydrolase - - - 0.0009444 49.0
HKD1_k127_1521409_3 Dynamin family - - - 3.58e-255 798.0
HKD1_k127_1521409_4 Belongs to the NifD NifK NifE NifN family K02587 - - 5.197e-251 779.0
HKD1_k127_1521409_5 Belongs to the NifD NifK NifE NifN family K02592 - - 5.017e-205 648.0
HKD1_k127_1521409_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 587.0
HKD1_k127_1521409_7 TIGRFAM Nitrogenase cofactor biosynthesis protein NifB K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 582.0
HKD1_k127_1521409_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 518.0
HKD1_k127_1521409_9 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 429.0
HKD1_k127_1521594_0 7TM-HD extracellular K07037 - - 1.25e-244 782.0
HKD1_k127_1521594_1 SMART Elongator protein 3 MiaB NifB - - - 1.175e-241 751.0
HKD1_k127_1521594_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000003212 159.0
HKD1_k127_1521594_11 - - - - 0.0000000000000000000000000000000000000003891 151.0
HKD1_k127_1521594_12 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.0000000000000000000000000000000002418 140.0
HKD1_k127_1521594_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000001925 92.0
HKD1_k127_1521594_14 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.000008095 54.0
HKD1_k127_1521594_15 transposition, DNA-mediated - - - 0.00000839 48.0
HKD1_k127_1521594_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 2.481e-195 615.0
HKD1_k127_1521594_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 465.0
HKD1_k127_1521594_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
HKD1_k127_1521594_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 402.0
HKD1_k127_1521594_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 350.0
HKD1_k127_1521594_7 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 334.0
HKD1_k127_1521594_8 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 317.0
HKD1_k127_1521594_9 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000002408 205.0
HKD1_k127_160063_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0 1034.0
HKD1_k127_160063_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.014e-211 665.0
HKD1_k127_160063_10 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 352.0
HKD1_k127_160063_11 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934,K13541,K21479 - 2.1.1.131,2.1.1.272,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 362.0
HKD1_k127_160063_12 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 335.0
HKD1_k127_160063_13 PFAM Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 336.0
HKD1_k127_160063_14 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 301.0
HKD1_k127_160063_15 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
HKD1_k127_160063_16 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 263.0
HKD1_k127_160063_17 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006492 262.0
HKD1_k127_160063_18 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000002486 260.0
HKD1_k127_160063_19 Precorrin-4 C(11)-methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
HKD1_k127_160063_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 6.921e-210 664.0
HKD1_k127_160063_20 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000001634 194.0
HKD1_k127_160063_21 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.0000000000000000000000000000000000000000000000002844 189.0
HKD1_k127_160063_22 NAD+ binding K12410 - - 0.0000000000000000000000000000000000000000000003542 174.0
HKD1_k127_160063_23 cobalt chelatase K02190 - 4.99.1.3 0.0000000000000000000000000000000000000000001253 170.0
HKD1_k127_160063_24 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000001574 106.0
HKD1_k127_160063_25 - - - - 0.0000000000002075 74.0
HKD1_k127_160063_26 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000003408 57.0
HKD1_k127_160063_27 Desulfoferrodoxin K05919 - 1.15.1.2 0.00001225 51.0
HKD1_k127_160063_28 methyltransferase - - - 0.0006651 43.0
HKD1_k127_160063_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 7.345e-196 621.0
HKD1_k127_160063_4 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 584.0
HKD1_k127_160063_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 499.0
HKD1_k127_160063_6 TIGRFAM cytochrome d oxidase, subunit II (cydB) K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 457.0
HKD1_k127_160063_7 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 457.0
HKD1_k127_160063_8 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 434.0
HKD1_k127_160063_9 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 398.0
HKD1_k127_1630911_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 0.0 2066.0
HKD1_k127_1630911_1 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0 1077.0
HKD1_k127_1630911_10 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD1_k127_1630911_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002566 267.0
HKD1_k127_1630911_12 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
HKD1_k127_1630911_13 - - - - 0.0000000000000000000000000000000000000000000000000001241 194.0
HKD1_k127_1630911_14 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000004476 185.0
HKD1_k127_1630911_15 GHKL domain - - - 0.00000000000000000000000000000000000000000000000946 196.0
HKD1_k127_1630911_16 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000004152 145.0
HKD1_k127_1630911_17 antisigma factor binding K03598 - - 0.0000000000000000006509 94.0
HKD1_k127_1630911_18 OsmC-like protein - - - 0.000000005123 65.0
HKD1_k127_1630911_2 4Fe-4S binding domain - - - 3.141e-243 763.0
HKD1_k127_1630911_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.183e-203 649.0
HKD1_k127_1630911_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 518.0
HKD1_k127_1630911_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 480.0
HKD1_k127_1630911_6 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 488.0
HKD1_k127_1630911_7 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HKD1_k127_1630911_8 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 304.0
HKD1_k127_1630911_9 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 299.0
HKD1_k127_1710600_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 529.0
HKD1_k127_1710600_3 - - - - 0.0000002692 60.0
HKD1_k127_1710600_4 Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor K11996 GO:0000003,GO:0001403,GO:0001558,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007114,GO:0008033,GO:0008150,GO:0008152,GO:0008641,GO:0009451,GO:0009987,GO:0010467,GO:0010570,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0016783,GO:0016874,GO:0016877,GO:0018117,GO:0018175,GO:0019538,GO:0019954,GO:0030447,GO:0032446,GO:0032447,GO:0032505,GO:0033554,GO:0034227,GO:0034470,GO:0034599,GO:0034641,GO:0034660,GO:0036211,GO:0036267,GO:0040007,GO:0040008,GO:0042221,GO:0042292,GO:0043170,GO:0043412,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051301,GO:0051716,GO:0065007,GO:0070566,GO:0070647,GO:0070733,GO:0070783,GO:0070784,GO:0070887,GO:0071704,GO:0090304,GO:1900428,GO:1901360,GO:1901564,GO:2000220 2.7.7.80,2.8.1.11 0.000002323 57.0
HKD1_k127_1714444_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 522.0
HKD1_k127_1714444_1 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000001638 228.0
HKD1_k127_1714444_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003152 218.0
HKD1_k127_1723028_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 2.836e-311 966.0
HKD1_k127_1723028_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.6e-214 671.0
HKD1_k127_1723028_10 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000006279 234.0
HKD1_k127_1723028_11 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000003372 211.0
HKD1_k127_1723028_12 NADH dehydrogenase K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001572 210.0
HKD1_k127_1723028_13 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000004102 160.0
HKD1_k127_1723028_14 - - - - 0.0000000000000000000000000000000000006098 146.0
HKD1_k127_1723028_15 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000007733 69.0
HKD1_k127_1723028_16 PFAM cytochrome c - - - 0.0000007104 57.0
HKD1_k127_1723028_2 Pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 580.0
HKD1_k127_1723028_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 520.0
HKD1_k127_1723028_4 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 493.0
HKD1_k127_1723028_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 457.0
HKD1_k127_1723028_6 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 423.0
HKD1_k127_1723028_7 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
HKD1_k127_1723028_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 284.0
HKD1_k127_1723028_9 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008408 253.0
HKD1_k127_1740996_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.304e-217 681.0
HKD1_k127_1740996_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 552.0
HKD1_k127_1740996_10 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000003132 147.0
HKD1_k127_1740996_12 - - - - 0.0000000000002345 81.0
HKD1_k127_1740996_13 - - - - 0.000000000006502 72.0
HKD1_k127_1740996_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 385.0
HKD1_k127_1740996_3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
HKD1_k127_1740996_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 327.0
HKD1_k127_1740996_5 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 314.0
HKD1_k127_1740996_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 283.0
HKD1_k127_1740996_7 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005942 280.0
HKD1_k127_1740996_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 258.0
HKD1_k127_1740996_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000094 213.0
HKD1_k127_1755580_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.375e-301 933.0
HKD1_k127_1755580_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 473.0
HKD1_k127_1755580_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000795 233.0
HKD1_k127_1755580_3 PFAM Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.00000000000000000000000000000000000000000000593 171.0
HKD1_k127_1755580_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000172 152.0
HKD1_k127_1755580_5 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000004475 110.0
HKD1_k127_1755580_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000009756 84.0
HKD1_k127_1884564_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.56e-197 627.0
HKD1_k127_1884564_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 516.0
HKD1_k127_1884564_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000002126 175.0
HKD1_k127_1884564_11 S23 ribosomal protein - - - 0.00000000000000000000000000009257 120.0
HKD1_k127_1884564_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 507.0
HKD1_k127_1884564_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 392.0
HKD1_k127_1884564_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 364.0
HKD1_k127_1884564_5 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
HKD1_k127_1884564_6 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 347.0
HKD1_k127_1884564_7 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 335.0
HKD1_k127_1884564_8 Prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
HKD1_k127_1884564_9 PFAM Uncharacterised protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
HKD1_k127_189830_0 formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 1.143e-228 721.0
HKD1_k127_189830_1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 515.0
HKD1_k127_189830_10 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00001554 50.0
HKD1_k127_189830_11 - - - - 0.0009424 46.0
HKD1_k127_189830_2 PFAM LemA K03744 - - 0.0000000000000000000000000000000000000000000000002004 182.0
HKD1_k127_189830_3 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000005677 162.0
HKD1_k127_189830_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000199 160.0
HKD1_k127_189830_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000004151 142.0
HKD1_k127_189830_6 Transposase K07493 - - 0.0000000000000000000001418 102.0
HKD1_k127_189830_7 Domain of unknown function (DUF4268) - - - 0.000000000000000004677 87.0
HKD1_k127_189830_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000001598 76.0
HKD1_k127_189830_9 PFAM Response regulator receiver domain - - - 0.000000007705 61.0
HKD1_k127_2015592_0 PFAM Major Facilitator Superfamily K08177 - - 2.847e-215 674.0
HKD1_k127_2015592_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 4.054e-204 644.0
HKD1_k127_2015592_10 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HKD1_k127_2015592_11 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000001088 227.0
HKD1_k127_2015592_12 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
HKD1_k127_2015592_13 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000000000000000005406 202.0
HKD1_k127_2015592_14 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000207 196.0
HKD1_k127_2015592_15 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000002802 188.0
HKD1_k127_2015592_16 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000002336 134.0
HKD1_k127_2015592_17 Thiamine-binding protein - - - 0.000000000000000000000000000004016 123.0
HKD1_k127_2015592_18 Response regulator, receiver K01733,K22010 - 4.2.3.1 0.0000000000000000000000000005564 116.0
HKD1_k127_2015592_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 4.112e-194 616.0
HKD1_k127_2015592_20 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000151 114.0
HKD1_k127_2015592_22 SPTR CopG domain protein DNA-binding domain protein - - - 0.00000000000002026 78.0
HKD1_k127_2015592_23 Protein of unknown function (DUF3096) - - - 0.000000006154 58.0
HKD1_k127_2015592_25 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000003978 51.0
HKD1_k127_2015592_3 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 589.0
HKD1_k127_2015592_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 565.0
HKD1_k127_2015592_5 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 492.0
HKD1_k127_2015592_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 481.0
HKD1_k127_2015592_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 432.0
HKD1_k127_2015592_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 394.0
HKD1_k127_2015592_9 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
HKD1_k127_2024672_0 Type II and III secretion system protein K02453 - - 4.675e-259 822.0
HKD1_k127_2024672_1 PFAM Type II secretion system protein E K02454 - - 4.098e-245 765.0
HKD1_k127_2024672_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 414.0
HKD1_k127_2024672_11 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 397.0
HKD1_k127_2024672_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 349.0
HKD1_k127_2024672_13 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 332.0
HKD1_k127_2024672_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 293.0
HKD1_k127_2024672_15 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 289.0
HKD1_k127_2024672_16 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002953 271.0
HKD1_k127_2024672_17 Conserved TM helix K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
HKD1_k127_2024672_18 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000909 237.0
HKD1_k127_2024672_19 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000007873 216.0
HKD1_k127_2024672_2 Amino acid permease - - - 2.996e-237 748.0
HKD1_k127_2024672_20 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000006271 189.0
HKD1_k127_2024672_21 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000008599 188.0
HKD1_k127_2024672_22 protein transport across the cell outer membrane K02457,K08084 - - 0.000000000000000000000000000000000000167 147.0
HKD1_k127_2024672_24 type IV pilus modification protein PilV K02458,K02671,K02681 - - 0.00000000000000000000000000008147 124.0
HKD1_k127_2024672_26 Late embryogenesis abundant protein - - - 0.0000000000000000009233 89.0
HKD1_k127_2024672_3 TIGRFAM Ammonium transporter K03320 - - 8.616e-207 657.0
HKD1_k127_2024672_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.075e-206 664.0
HKD1_k127_2024672_5 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 578.0
HKD1_k127_2024672_6 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 548.0
HKD1_k127_2024672_7 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 527.0
HKD1_k127_2024672_8 COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 445.0
HKD1_k127_2024672_9 PFAM Fimbrial assembly K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 426.0
HKD1_k127_202536_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 3.668e-293 919.0
HKD1_k127_202536_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 8.233e-284 879.0
HKD1_k127_202536_10 helix_turn_helix, mercury resistance - - - 0.0000000000000004927 84.0
HKD1_k127_202536_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 582.0
HKD1_k127_202536_3 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 455.0
HKD1_k127_202536_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 435.0
HKD1_k127_202536_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 383.0
HKD1_k127_202536_6 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 313.0
HKD1_k127_202536_7 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000000000000000000004019 178.0
HKD1_k127_202536_8 PFAM ROSMUCR transcriptional regulator - - - 0.00000000000000000000000000000000000000008299 155.0
HKD1_k127_202536_9 Right handed beta helix region - - - 0.00000000000000000000000000000007512 134.0
HKD1_k127_2027554_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0 1045.0
HKD1_k127_2027554_1 COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - - 0.0 1037.0
HKD1_k127_2027554_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
HKD1_k127_2027554_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000001226 83.0
HKD1_k127_2027554_4 Universal stress protein - - - 0.0000000000000871 75.0
HKD1_k127_2103944_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.112e-303 940.0
HKD1_k127_2103944_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.06e-207 658.0
HKD1_k127_2103944_10 - - - - 0.00000000000000000000000002671 109.0
HKD1_k127_2103944_11 - - - - 0.000000000000000000001777 98.0
HKD1_k127_2103944_13 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD1_k127_2103944_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 501.0
HKD1_k127_2103944_3 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 372.0
HKD1_k127_2103944_4 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 323.0
HKD1_k127_2103944_5 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003924 255.0
HKD1_k127_2103944_6 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000004665 232.0
HKD1_k127_2103944_7 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000149 218.0
HKD1_k127_2103944_8 - - - - 0.000000000000000000000000000000000000000000000000004591 184.0
HKD1_k127_2103944_9 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000002006 197.0
HKD1_k127_2122671_0 Sulfatase K01130 - 3.1.6.1 0.0 1410.0
HKD1_k127_2122671_1 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HKD1_k127_2122671_2 Transposase - - - 0.0000000000003062 70.0
HKD1_k127_2122671_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000009393 79.0
HKD1_k127_2130255_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0 1157.0
HKD1_k127_2130255_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.153e-287 908.0
HKD1_k127_2130255_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 574.0
HKD1_k127_2130255_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
HKD1_k127_2130255_12 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 548.0
HKD1_k127_2130255_13 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 545.0
HKD1_k127_2130255_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 535.0
HKD1_k127_2130255_15 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 526.0
HKD1_k127_2130255_16 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 511.0
HKD1_k127_2130255_17 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 496.0
HKD1_k127_2130255_18 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 487.0
HKD1_k127_2130255_19 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 463.0
HKD1_k127_2130255_2 aconitate hydratase K01681 - 4.2.1.3 1.502e-280 876.0
HKD1_k127_2130255_20 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 444.0
HKD1_k127_2130255_21 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 415.0
HKD1_k127_2130255_22 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
HKD1_k127_2130255_23 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 420.0
HKD1_k127_2130255_24 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 402.0
HKD1_k127_2130255_25 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 401.0
HKD1_k127_2130255_26 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 398.0
HKD1_k127_2130255_27 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 382.0
HKD1_k127_2130255_28 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
HKD1_k127_2130255_29 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
HKD1_k127_2130255_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.7e-233 726.0
HKD1_k127_2130255_30 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 357.0
HKD1_k127_2130255_31 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 350.0
HKD1_k127_2130255_32 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 383.0
HKD1_k127_2130255_33 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 337.0
HKD1_k127_2130255_34 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
HKD1_k127_2130255_35 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 321.0
HKD1_k127_2130255_36 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 317.0
HKD1_k127_2130255_37 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 311.0
HKD1_k127_2130255_38 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
HKD1_k127_2130255_39 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002141 279.0
HKD1_k127_2130255_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.095e-232 741.0
HKD1_k127_2130255_40 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
HKD1_k127_2130255_41 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 254.0
HKD1_k127_2130255_42 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000002032 246.0
HKD1_k127_2130255_43 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005918 267.0
HKD1_k127_2130255_44 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
HKD1_k127_2130255_45 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004857 239.0
HKD1_k127_2130255_46 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000002146 233.0
HKD1_k127_2130255_48 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000001244 222.0
HKD1_k127_2130255_49 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
HKD1_k127_2130255_5 PFAM Radical SAM - - - 1.036e-229 724.0
HKD1_k127_2130255_50 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000002757 218.0
HKD1_k127_2130255_51 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000000000000000000000001032 222.0
HKD1_k127_2130255_52 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000002388 241.0
HKD1_k127_2130255_53 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000001706 214.0
HKD1_k127_2130255_54 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000003812 211.0
HKD1_k127_2130255_55 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000043 206.0
HKD1_k127_2130255_56 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000007432 205.0
HKD1_k127_2130255_57 - - - - 0.00000000000000000000000000000000000000000000000000000008125 203.0
HKD1_k127_2130255_58 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000008993 199.0
HKD1_k127_2130255_59 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001737 211.0
HKD1_k127_2130255_6 Endoribonuclease that initiates mRNA decay K18682 - - 1.639e-225 712.0
HKD1_k127_2130255_60 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000000000000002417 182.0
HKD1_k127_2130255_61 Rubrerythrin K19824 - - 0.000000000000000000000000000000000000000000000008204 177.0
HKD1_k127_2130255_62 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000006819 176.0
HKD1_k127_2130255_63 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000001028 169.0
HKD1_k127_2130255_64 zinc ion binding K06204 - - 0.0000000000000000000000000000000000000000000001319 172.0
HKD1_k127_2130255_65 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000002279 169.0
HKD1_k127_2130255_66 Universal stress protein family - - - 0.00000000000000000000000000000000000000001049 159.0
HKD1_k127_2130255_67 Belongs to the Fur family K09825,K22297 - - 0.000000000000000000000000000000000000000144 154.0
HKD1_k127_2130255_68 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000008674 144.0
HKD1_k127_2130255_69 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000001071 142.0
HKD1_k127_2130255_7 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 3.985e-223 713.0
HKD1_k127_2130255_70 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000044 136.0
HKD1_k127_2130255_72 Protein of unknown function (DUF2283) - - - 0.000000000000000000000000000001471 122.0
HKD1_k127_2130255_73 membrane K08978 - - 0.00000000000000000000000002188 113.0
HKD1_k127_2130255_74 Tautomerase enzyme - - - 0.0000000000000000000000003907 106.0
HKD1_k127_2130255_75 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000473 105.0
HKD1_k127_2130255_76 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000002871 102.0
HKD1_k127_2130255_77 lipolytic protein G-D-S-L family - - - 0.00000000000000000000002267 113.0
HKD1_k127_2130255_78 - - - - 0.00000000000000000000005491 105.0
HKD1_k127_2130255_79 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000002016 103.0
HKD1_k127_2130255_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.261e-194 614.0
HKD1_k127_2130255_80 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000002113 100.0
HKD1_k127_2130255_81 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000006856 91.0
HKD1_k127_2130255_82 Protein of unknown function (DUF559) - - - 0.000000000000000007089 84.0
HKD1_k127_2130255_83 Protein of unknown function (DUF2442) - - - 0.00000000000000008583 81.0
HKD1_k127_2130255_84 nuclease activity K06218 - - 0.000000000000004286 78.0
HKD1_k127_2130255_85 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000001037 68.0
HKD1_k127_2130255_86 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000039 66.0
HKD1_k127_2130255_87 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000009358 66.0
HKD1_k127_2130255_88 Protein of unknown function (DUF559) - - - 0.0000000004199 61.0
HKD1_k127_2130255_89 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000666 66.0
HKD1_k127_2130255_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 591.0
HKD1_k127_2130255_90 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000001953 63.0
HKD1_k127_2130255_91 Regulatory protein, FmdB family - - - 0.00000002557 59.0
HKD1_k127_2130255_94 Belongs to the Fur family K03711 - - 0.00000007399 59.0
HKD1_k127_2130255_95 Protein of unknown function (DUF1566) - - - 0.0000002249 59.0
HKD1_k127_2130255_96 - - - - 0.000006696 52.0
HKD1_k127_2130255_97 Serine aminopeptidase, S33 - - - 0.0001157 51.0
HKD1_k127_2130255_98 Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K07008 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368 3.5.1.118 0.0003582 51.0
HKD1_k127_2130255_99 Histidine kinase-like ATPase domain - - - 0.0005536 46.0
HKD1_k127_2222223_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1152.0
HKD1_k127_2222223_1 Acetyl xylan esterase (AXE1) - - - 3.5e-286 891.0
HKD1_k127_2222223_10 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 497.0
HKD1_k127_2222223_11 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 480.0
HKD1_k127_2222223_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 467.0
HKD1_k127_2222223_13 cysteine synthase A K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
HKD1_k127_2222223_14 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 449.0
HKD1_k127_2222223_15 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HKD1_k127_2222223_16 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 404.0
HKD1_k127_2222223_17 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
HKD1_k127_2222223_18 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 338.0
HKD1_k127_2222223_19 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
HKD1_k127_2222223_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.865e-240 775.0
HKD1_k127_2222223_20 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
HKD1_k127_2222223_21 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
HKD1_k127_2222223_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000044 220.0
HKD1_k127_2222223_23 PIN domain - - - 0.00000000000000000000000000000000000000001381 156.0
HKD1_k127_2222223_24 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000000000000007939 137.0
HKD1_k127_2222223_25 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000003312 121.0
HKD1_k127_2222223_26 Stress responsive alpha-beta barrel - - - 0.00000000000000000000000002716 110.0
HKD1_k127_2222223_27 SpoVT / AbrB like domain - - - 0.000000000000000000000439 97.0
HKD1_k127_2222223_28 Protein of unknown function DUF86 - - - 0.000000000000000003679 86.0
HKD1_k127_2222223_3 Pfam:DUF490 K09800 - - 4.646e-215 711.0
HKD1_k127_2222223_30 transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000002401 73.0
HKD1_k127_2222223_31 Rhodanese-like domain K01069 - 3.1.2.6 0.000000002332 64.0
HKD1_k127_2222223_32 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD1_k127_2222223_4 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 2.357e-208 662.0
HKD1_k127_2222223_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 9.915e-199 625.0
HKD1_k127_2222223_6 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 623.0
HKD1_k127_2222223_7 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 563.0
HKD1_k127_2222223_8 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 537.0
HKD1_k127_2222223_9 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 514.0
HKD1_k127_2222353_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 1.277e-197 625.0
HKD1_k127_2222353_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 580.0
HKD1_k127_2222353_10 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
HKD1_k127_2222353_11 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD1_k127_2222353_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000007096 177.0
HKD1_k127_2222353_13 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000000000002249 159.0
HKD1_k127_2222353_14 - - - - 0.00000000004058 72.0
HKD1_k127_2222353_15 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD1_k127_2222353_2 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 458.0
HKD1_k127_2222353_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 420.0
HKD1_k127_2222353_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 395.0
HKD1_k127_2222353_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 388.0
HKD1_k127_2222353_6 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 362.0
HKD1_k127_2222353_7 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 331.0
HKD1_k127_2222353_8 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
HKD1_k127_2222353_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 297.0
HKD1_k127_2230435_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 512.0
HKD1_k127_2230435_1 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 486.0
HKD1_k127_2230435_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 455.0
HKD1_k127_2230435_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 319.0
HKD1_k127_2230435_4 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000001972 243.0
HKD1_k127_2230435_5 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001423 243.0
HKD1_k127_2230435_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000003699 143.0
HKD1_k127_2230435_7 - - - - 0.00000000009848 61.0
HKD1_k127_228415_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0 1457.0
HKD1_k127_228415_1 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 9.324e-255 805.0
HKD1_k127_228415_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 301.0
HKD1_k127_228415_11 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 291.0
HKD1_k127_228415_12 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 290.0
HKD1_k127_228415_13 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004716 273.0
HKD1_k127_228415_14 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000001199 245.0
HKD1_k127_228415_15 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000002665 216.0
HKD1_k127_228415_16 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000002498 207.0
HKD1_k127_228415_17 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000001247 189.0
HKD1_k127_228415_18 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000002199 195.0
HKD1_k127_228415_19 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000007399 189.0
HKD1_k127_228415_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 524.0
HKD1_k127_228415_20 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000001796 166.0
HKD1_k127_228415_21 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000005644 161.0
HKD1_k127_228415_22 DGC domain - - - 0.000000000000000000000000000000000000000487 152.0
HKD1_k127_228415_23 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000000000000000003166 153.0
HKD1_k127_228415_24 IMG reference gene - - - 0.00000000000000000000000000000000000009353 147.0
HKD1_k127_228415_25 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000008131 144.0
HKD1_k127_228415_26 DGC domain - - - 0.00000000000000000000000000000000002883 139.0
HKD1_k127_228415_27 Thioredoxin domain - - - 0.0000000000000000000000000000000002079 144.0
HKD1_k127_228415_28 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000003848 135.0
HKD1_k127_228415_29 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000003067 138.0
HKD1_k127_228415_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 489.0
HKD1_k127_228415_30 Thioredoxin domain - - - 0.0000000000000000000000000000005203 123.0
HKD1_k127_228415_31 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000006309 125.0
HKD1_k127_228415_32 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000146 119.0
HKD1_k127_228415_33 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000006349 116.0
HKD1_k127_228415_34 Sigma-70, region 4 K03088 - - 0.000000000000000000000000006894 117.0
HKD1_k127_228415_35 Phage integrase family K03733 - - 0.00000000000000000000003057 103.0
HKD1_k127_228415_36 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000001211 94.0
HKD1_k127_228415_37 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000006982 76.0
HKD1_k127_228415_38 - - - - 0.000000000003843 70.0
HKD1_k127_228415_39 response regulator - - - 0.00000000003061 69.0
HKD1_k127_228415_4 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 467.0
HKD1_k127_228415_40 peroxiredoxin activity K01607 - 4.1.1.44 0.000002332 52.0
HKD1_k127_228415_5 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 393.0
HKD1_k127_228415_6 Phosphonate ABC transporter, periplasmic K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 376.0
HKD1_k127_228415_7 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 365.0
HKD1_k127_228415_8 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 322.0
HKD1_k127_228415_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 318.0
HKD1_k127_2288769_0 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 1.524e-216 679.0
HKD1_k127_2288769_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 3.182e-199 633.0
HKD1_k127_2288769_10 - - - - 0.0000000000000000000000000000000000000001365 155.0
HKD1_k127_2288769_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000003123 97.0
HKD1_k127_2288769_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 544.0
HKD1_k127_2288769_3 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 508.0
HKD1_k127_2288769_4 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 389.0
HKD1_k127_2288769_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 360.0
HKD1_k127_2288769_6 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
HKD1_k127_2288769_7 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000003628 198.0
HKD1_k127_2288769_8 - - - - 0.00000000000000000000000000000000000000000000001386 180.0
HKD1_k127_2288769_9 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000323 166.0
HKD1_k127_2296738_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 1.395e-255 801.0
HKD1_k127_2296738_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 490.0
HKD1_k127_2296738_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 471.0
HKD1_k127_2296738_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 326.0
HKD1_k127_2296738_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
HKD1_k127_2296738_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000001087 269.0
HKD1_k127_2296738_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000002773 208.0
HKD1_k127_2296738_7 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000001358 135.0
HKD1_k127_2296738_8 - - - - 0.0000000000000000000000000000007701 128.0
HKD1_k127_2351025_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 430.0
HKD1_k127_2351025_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 403.0
HKD1_k127_2351025_2 YdjC-like protein K03478 - 3.5.1.105 0.00000002203 57.0
HKD1_k127_2398563_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.029e-255 794.0
HKD1_k127_2398563_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 535.0
HKD1_k127_2398563_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.0000000000000000000000000000000000000000000000000000000001404 213.0
HKD1_k127_2398563_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000001426 201.0
HKD1_k127_2398563_12 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD1_k127_2398563_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 471.0
HKD1_k127_2398563_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 430.0
HKD1_k127_2398563_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 413.0
HKD1_k127_2398563_5 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 399.0
HKD1_k127_2398563_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 389.0
HKD1_k127_2398563_7 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 298.0
HKD1_k127_2398563_8 Transcriptional regulator, TetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005065 260.0
HKD1_k127_2398563_9 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000003054 254.0
HKD1_k127_2409426_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 546.0
HKD1_k127_2409426_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 475.0
HKD1_k127_2409426_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 393.0
HKD1_k127_2409426_3 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000002108 239.0
HKD1_k127_2409426_4 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000007381 120.0
HKD1_k127_2409426_5 - - - - 0.00000000001654 68.0
HKD1_k127_241808_0 BadF BadG BcrA BcrD - - - 0.0 2010.0
HKD1_k127_241808_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 529.0
HKD1_k127_241808_2 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 323.0
HKD1_k127_241808_3 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
HKD1_k127_241808_4 integral membrane protein - - - 0.0000000000000000000000000000000000000000000002232 176.0
HKD1_k127_241808_5 integral membrane protein - - - 0.0000000000000004263 88.0
HKD1_k127_241808_6 - - - - 0.0000000000000006816 78.0
HKD1_k127_241808_9 - - - - 0.000004944 54.0
HKD1_k127_2444989_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.098e-221 689.0
HKD1_k127_2444989_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.977e-207 653.0
HKD1_k127_2444989_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 327.0
HKD1_k127_2444989_11 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
HKD1_k127_2444989_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001126 226.0
HKD1_k127_2444989_13 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000003002 190.0
HKD1_k127_2444989_14 integral membrane protein - - - 0.000000000000000000000000000000000000000000962 162.0
HKD1_k127_2444989_15 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000001839 96.0
HKD1_k127_2444989_16 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.000000000000001796 89.0
HKD1_k127_2444989_17 monooxygenase activity - - - 0.00000000000002013 76.0
HKD1_k127_2444989_18 - - - - 0.000000002432 66.0
HKD1_k127_2444989_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 600.0
HKD1_k127_2444989_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 599.0
HKD1_k127_2444989_4 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 542.0
HKD1_k127_2444989_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 451.0
HKD1_k127_2444989_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 445.0
HKD1_k127_2444989_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 400.0
HKD1_k127_2444989_8 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
HKD1_k127_2444989_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 342.0
HKD1_k127_2540899_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1235.0
HKD1_k127_2540899_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1167.0
HKD1_k127_2540899_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 436.0
HKD1_k127_2540899_3 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
HKD1_k127_2540899_4 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000002221 169.0
HKD1_k127_2540899_5 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000007416 166.0
HKD1_k127_2540899_6 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000004222 138.0
HKD1_k127_2540899_7 transposition, DNA-mediated - - - 0.0000000000000000000001054 99.0
HKD1_k127_2540899_9 L,D-transpeptidase catalytic domain - - - 0.000000002523 68.0
HKD1_k127_2753425_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1157.0
HKD1_k127_2753425_1 PFAM Cytochrome C K04561 - 1.7.2.5 0.0 1114.0
HKD1_k127_2753425_10 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 485.0
HKD1_k127_2753425_11 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 474.0
HKD1_k127_2753425_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HKD1_k127_2753425_13 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
HKD1_k127_2753425_14 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 451.0
HKD1_k127_2753425_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 439.0
HKD1_k127_2753425_16 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 432.0
HKD1_k127_2753425_17 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 433.0
HKD1_k127_2753425_18 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 388.0
HKD1_k127_2753425_19 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 375.0
HKD1_k127_2753425_2 Large extracellular alpha-helical protein K06894 - - 0.0 1105.0
HKD1_k127_2753425_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 377.0
HKD1_k127_2753425_21 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 327.0
HKD1_k127_2753425_22 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 319.0
HKD1_k127_2753425_23 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 315.0
HKD1_k127_2753425_24 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002977 281.0
HKD1_k127_2753425_25 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
HKD1_k127_2753425_26 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000002233 271.0
HKD1_k127_2753425_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000294 258.0
HKD1_k127_2753425_28 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
HKD1_k127_2753425_29 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003488 245.0
HKD1_k127_2753425_3 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 3.178e-291 904.0
HKD1_k127_2753425_30 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000001464 252.0
HKD1_k127_2753425_31 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
HKD1_k127_2753425_32 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000004616 216.0
HKD1_k127_2753425_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
HKD1_k127_2753425_34 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HKD1_k127_2753425_35 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
HKD1_k127_2753425_36 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000004712 214.0
HKD1_k127_2753425_37 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
HKD1_k127_2753425_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000000000000136 186.0
HKD1_k127_2753425_39 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000001813 189.0
HKD1_k127_2753425_4 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 7.908e-272 859.0
HKD1_k127_2753425_40 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000009973 186.0
HKD1_k127_2753425_41 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000001256 164.0
HKD1_k127_2753425_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000002586 141.0
HKD1_k127_2753425_43 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000851 146.0
HKD1_k127_2753425_44 PFAM Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000003941 133.0
HKD1_k127_2753425_45 - - - - 0.000000000000000000000000000000004676 135.0
HKD1_k127_2753425_46 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000003461 113.0
HKD1_k127_2753425_5 PFAM Transketolase K00615 - 2.2.1.1 1.375e-250 787.0
HKD1_k127_2753425_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.089e-208 660.0
HKD1_k127_2753425_7 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 601.0
HKD1_k127_2753425_8 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 544.0
HKD1_k127_2753425_9 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 553.0
HKD1_k127_285000_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.267e-272 856.0
HKD1_k127_285000_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 585.0
HKD1_k127_285000_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 539.0
HKD1_k127_285000_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 474.0
HKD1_k127_285000_4 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 432.0
HKD1_k127_285000_5 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 413.0
HKD1_k127_285000_6 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 296.0
HKD1_k127_285000_7 QueT transporter K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
HKD1_k127_285000_8 Right handed beta helix region - - - 0.000000000000000000000001215 113.0
HKD1_k127_2869801_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 3.365e-292 907.0
HKD1_k127_2869801_1 AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 1.961e-289 895.0
HKD1_k127_2869801_10 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000002381 183.0
HKD1_k127_2869801_11 family 9 - - - 0.000000000000000000000000000000000000000000000006461 186.0
HKD1_k127_2869801_12 Glycosyl transferases group 1 K06338 - - 0.0000000000000000000000000000000000000006574 164.0
HKD1_k127_2869801_13 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000001167 158.0
HKD1_k127_2869801_14 - - - - 0.0000000000000000000000000003105 117.0
HKD1_k127_2869801_15 Domain of unknown function (DUF4926) - - - 0.0000000000000000000001317 99.0
HKD1_k127_2869801_16 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.000000000000000002406 98.0
HKD1_k127_2869801_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 8.176e-200 631.0
HKD1_k127_2869801_3 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 592.0
HKD1_k127_2869801_4 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 563.0
HKD1_k127_2869801_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 349.0
HKD1_k127_2869801_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 287.0
HKD1_k127_2869801_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000008706 227.0
HKD1_k127_2869801_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000001619 229.0
HKD1_k127_2869801_9 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000003109 208.0
HKD1_k127_2886512_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 499.0
HKD1_k127_2886512_1 PFAM Peptidase M20 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 294.0
HKD1_k127_2886512_2 Protein of unknown function (DUF1641) - - - 0.00000000000000000000000000000000000000000000000000286 190.0
HKD1_k127_2886512_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000805 128.0
HKD1_k127_2886512_4 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD1_k127_2963523_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1361.0
HKD1_k127_2963523_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 2.638e-212 669.0
HKD1_k127_2963523_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 425.0
HKD1_k127_2963523_11 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 380.0
HKD1_k127_2963523_12 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 381.0
HKD1_k127_2963523_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 373.0
HKD1_k127_2963523_14 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 360.0
HKD1_k127_2963523_15 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 332.0
HKD1_k127_2963523_16 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 325.0
HKD1_k127_2963523_17 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 336.0
HKD1_k127_2963523_18 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 315.0
HKD1_k127_2963523_19 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HKD1_k127_2963523_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 4.354e-204 643.0
HKD1_k127_2963523_20 PFAM NAD dependent epimerase dehydratase family K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 298.0
HKD1_k127_2963523_21 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 276.0
HKD1_k127_2963523_22 domain, Protein K15125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000282 297.0
HKD1_k127_2963523_23 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006746 276.0
HKD1_k127_2963523_24 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002101 265.0
HKD1_k127_2963523_25 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000184 263.0
HKD1_k127_2963523_26 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
HKD1_k127_2963523_27 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000005683 233.0
HKD1_k127_2963523_28 NIL - - - 0.00000000000000000000000000000000000000000000000000000000000000005197 229.0
HKD1_k127_2963523_29 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000002024 226.0
HKD1_k127_2963523_3 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 2.33e-198 623.0
HKD1_k127_2963523_30 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000003554 200.0
HKD1_k127_2963523_31 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.000000000000000000000000000000000000000000000000000001969 195.0
HKD1_k127_2963523_32 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000001539 184.0
HKD1_k127_2963523_33 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000007698 168.0
HKD1_k127_2963523_34 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000002239 172.0
HKD1_k127_2963523_35 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000000000185 137.0
HKD1_k127_2963523_36 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.000000000000000000000000000003241 123.0
HKD1_k127_2963523_37 Belongs to the MtfA family K09933 - - 0.00000000000000000000000007647 109.0
HKD1_k127_2963523_38 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000001301 80.0
HKD1_k127_2963523_39 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000001873 69.0
HKD1_k127_2963523_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
HKD1_k127_2963523_40 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000002462 52.0
HKD1_k127_2963523_5 domain, Protein K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 519.0
HKD1_k127_2963523_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 499.0
HKD1_k127_2963523_7 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 480.0
HKD1_k127_2963523_8 Multicopper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 484.0
HKD1_k127_2963523_9 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
HKD1_k127_297170_0 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.932e-231 720.0
HKD1_k127_297170_1 RNB K01147,K12573 - 3.1.13.1 6.459e-220 700.0
HKD1_k127_297170_10 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 261.0
HKD1_k127_297170_11 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000001201 252.0
HKD1_k127_297170_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000001271 243.0
HKD1_k127_297170_13 ABC transporter substrate binding protein K01989,K05832 - - 0.000000000000000000000000000000000000000000000000000000000003456 221.0
HKD1_k127_297170_14 FecR protein - - - 0.0000000000000000000000000000000000000001202 163.0
HKD1_k127_297170_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000004563 108.0
HKD1_k127_297170_17 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000007341 103.0
HKD1_k127_297170_18 protein with SCP PR1 domains - - - 0.00000000000000000002059 98.0
HKD1_k127_297170_19 ISXO2-like transposase domain - - - 0.00000000000005343 72.0
HKD1_k127_297170_2 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 1.332e-209 654.0
HKD1_k127_297170_20 Hypothetical methyltransferase - - - 0.0000000005713 68.0
HKD1_k127_297170_21 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD1_k127_297170_22 helix_turn_helix, arabinose operon control protein K07720 - - 0.0006156 49.0
HKD1_k127_297170_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.923e-199 633.0
HKD1_k127_297170_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 578.0
HKD1_k127_297170_5 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 539.0
HKD1_k127_297170_6 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 493.0
HKD1_k127_297170_7 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 405.0
HKD1_k127_297170_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000263 274.0
HKD1_k127_297170_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002822 269.0
HKD1_k127_3031441_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1511.0
HKD1_k127_3031441_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1191.0
HKD1_k127_3031441_10 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 302.0
HKD1_k127_3031441_11 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 303.0
HKD1_k127_3031441_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000946 284.0
HKD1_k127_3031441_13 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002042 271.0
HKD1_k127_3031441_14 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
HKD1_k127_3031441_15 DUF3160 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001597 261.0
HKD1_k127_3031441_16 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003484 234.0
HKD1_k127_3031441_17 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000004078 216.0
HKD1_k127_3031441_18 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000007927 119.0
HKD1_k127_3031441_19 Putative Tad-like Flp pilus-assembly - - - 0.0000000000000000000000000007175 126.0
HKD1_k127_3031441_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1047.0
HKD1_k127_3031441_20 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000558 112.0
HKD1_k127_3031441_21 FAD dependent oxidoreductase - - - 0.0000000000000000000001296 98.0
HKD1_k127_3031441_22 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000002562 97.0
HKD1_k127_3031441_23 - - - - 0.000000000000000002654 89.0
HKD1_k127_3031441_24 Peptidase family M23 K21472 - - 0.00000000000000004834 94.0
HKD1_k127_3031441_25 Phage integrase family K03733 - - 0.00000000000000006178 85.0
HKD1_k127_3031441_26 cheY-homologous receiver domain - - - 0.0000000000000002429 90.0
HKD1_k127_3031441_27 Fibronectin type III domain - - - 0.0000000000005175 82.0
HKD1_k127_3031441_3 Signal transduction histidine kinase - - - 7.444e-305 951.0
HKD1_k127_3031441_4 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 5.431e-244 763.0
HKD1_k127_3031441_5 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 6.798e-215 678.0
HKD1_k127_3031441_6 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 426.0
HKD1_k127_3031441_7 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 405.0
HKD1_k127_3031441_8 Memo-like protein K06990,K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 397.0
HKD1_k127_3031441_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 304.0
HKD1_k127_3101315_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.639e-303 944.0
HKD1_k127_3101315_1 Conserved hypothetical protein 698 - - - 1.665e-249 777.0
HKD1_k127_3101315_10 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006336 281.0
HKD1_k127_3101315_11 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
HKD1_k127_3101315_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
HKD1_k127_3101315_13 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000001143 218.0
HKD1_k127_3101315_14 cell septum assembly - - - 0.000000000000000000000000000000000000000001019 165.0
HKD1_k127_3101315_16 - - - - 0.00000000000000000000004654 99.0
HKD1_k127_3101315_17 Uncharacterised ArCR, COG2043 - - - 0.000000000000000001081 95.0
HKD1_k127_3101315_18 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000005235 86.0
HKD1_k127_3101315_19 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000009869 84.0
HKD1_k127_3101315_2 Conserved hypothetical protein 698 - - - 2.418e-221 699.0
HKD1_k127_3101315_20 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.000000000000004942 77.0
HKD1_k127_3101315_3 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 565.0
HKD1_k127_3101315_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 493.0
HKD1_k127_3101315_5 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 407.0
HKD1_k127_3101315_6 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 369.0
HKD1_k127_3101315_7 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 332.0
HKD1_k127_3101315_8 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
HKD1_k127_3101315_9 Flavodoxin-like fold K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
HKD1_k127_3109839_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 2.695e-204 652.0
HKD1_k127_3109839_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 426.0
HKD1_k127_3109839_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
HKD1_k127_3109839_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000001094 243.0
HKD1_k127_3109839_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K21020 - 2.7.7.65 0.0000000000000000000000000000000000000000003915 179.0
HKD1_k127_3109839_5 Cold shock K03704 - - 0.000000000000000000001002 96.0
HKD1_k127_3109839_6 Protein of unknown function (DUF2892) - - - 0.000000000000000006146 85.0
HKD1_k127_3115821_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 5.809e-278 874.0
HKD1_k127_3115821_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.601e-262 826.0
HKD1_k127_3115821_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 438.0
HKD1_k127_3115821_11 Pterin binding enzyme K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 414.0
HKD1_k127_3115821_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 419.0
HKD1_k127_3115821_13 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 403.0
HKD1_k127_3115821_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 405.0
HKD1_k127_3115821_15 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 390.0
HKD1_k127_3115821_16 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 313.0
HKD1_k127_3115821_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
HKD1_k127_3115821_18 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
HKD1_k127_3115821_19 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
HKD1_k127_3115821_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 608.0
HKD1_k127_3115821_20 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
HKD1_k127_3115821_21 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000003106 252.0
HKD1_k127_3115821_22 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HKD1_k127_3115821_23 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000000000000000000001699 180.0
HKD1_k127_3115821_24 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000735 167.0
HKD1_k127_3115821_25 protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000003242 143.0
HKD1_k127_3115821_26 YacP-like NYN domain K06962 - - 0.000000000000000000000000000000000008 141.0
HKD1_k127_3115821_27 - - - - 0.000000000000000000000000000000004856 130.0
HKD1_k127_3115821_28 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000002191 123.0
HKD1_k127_3115821_29 Hypothetical methyltransferase - - - 0.00000000000000000000000008203 115.0
HKD1_k127_3115821_3 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 602.0
HKD1_k127_3115821_30 PFAM CBS domain K04767 - - 0.0000000000000000000001459 99.0
HKD1_k127_3115821_31 tetratricopeptide repeat - - - 0.00000000000000008021 90.0
HKD1_k127_3115821_32 PFAM Heavy metal transport detoxification protein - - - 0.00000000000001811 75.0
HKD1_k127_3115821_33 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000002533 72.0
HKD1_k127_3115821_34 - - - - 0.0000009684 56.0
HKD1_k127_3115821_35 VanZ like family - - - 0.00001821 53.0
HKD1_k127_3115821_36 Domain of unknown function (DUF1772) - - - 0.00002984 52.0
HKD1_k127_3115821_4 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 589.0
HKD1_k127_3115821_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 579.0
HKD1_k127_3115821_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 571.0
HKD1_k127_3115821_7 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 562.0
HKD1_k127_3115821_8 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 542.0
HKD1_k127_3115821_9 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 494.0
HKD1_k127_3126722_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1738.0
HKD1_k127_3126722_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1386.0
HKD1_k127_3126722_10 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
HKD1_k127_3126722_11 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 518.0
HKD1_k127_3126722_12 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 518.0
HKD1_k127_3126722_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 506.0
HKD1_k127_3126722_14 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 496.0
HKD1_k127_3126722_15 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 474.0
HKD1_k127_3126722_16 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 469.0
HKD1_k127_3126722_17 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 456.0
HKD1_k127_3126722_18 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 437.0
HKD1_k127_3126722_19 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 425.0
HKD1_k127_3126722_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.914e-268 833.0
HKD1_k127_3126722_20 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 415.0
HKD1_k127_3126722_21 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 392.0
HKD1_k127_3126722_22 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 401.0
HKD1_k127_3126722_23 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 382.0
HKD1_k127_3126722_24 Cytochrome c5530 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 387.0
HKD1_k127_3126722_25 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 344.0
HKD1_k127_3126722_26 signal-transduction protein with CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 327.0
HKD1_k127_3126722_27 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 303.0
HKD1_k127_3126722_28 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 293.0
HKD1_k127_3126722_29 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 291.0
HKD1_k127_3126722_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 1.242e-261 831.0
HKD1_k127_3126722_30 aspartate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 291.0
HKD1_k127_3126722_31 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 307.0
HKD1_k127_3126722_32 Histidine kinase K02668,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002421 300.0
HKD1_k127_3126722_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000006868 216.0
HKD1_k127_3126722_34 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
HKD1_k127_3126722_35 acetyltransferase K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000009793 203.0
HKD1_k127_3126722_36 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000001798 201.0
HKD1_k127_3126722_37 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000001165 173.0
HKD1_k127_3126722_38 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000009808 172.0
HKD1_k127_3126722_39 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000005289 161.0
HKD1_k127_3126722_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.493e-238 745.0
HKD1_k127_3126722_40 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002034 156.0
HKD1_k127_3126722_41 membrane K00389 - - 0.00000000000000000000000000000000003138 146.0
HKD1_k127_3126722_42 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000002174 136.0
HKD1_k127_3126722_43 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000001107 130.0
HKD1_k127_3126722_44 Sec-independent protein translocase protein TatA K03116 - - 0.000000000000000000000000000002939 122.0
HKD1_k127_3126722_45 Putative Tad-like Flp pilus-assembly - - - 0.00000000000000000000000000001131 131.0
HKD1_k127_3126722_46 Putative Tad-like Flp pilus-assembly - - - 0.00000000000000000000000000004724 129.0
HKD1_k127_3126722_47 Sec-independent protein translocase protein TatA K03116,K03117,K03646 - - 0.0000000000000003441 82.0
HKD1_k127_3126722_49 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000004408 51.0
HKD1_k127_3126722_5 His Kinase A (phosphoacceptor) domain - - - 6.434e-215 678.0
HKD1_k127_3126722_6 Fe-S oxidoreductase - - - 4.921e-199 640.0
HKD1_k127_3126722_7 - K03293 - - 1.876e-196 620.0
HKD1_k127_3126722_8 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 573.0
HKD1_k127_3126722_9 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 552.0
HKD1_k127_3129382_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 387.0
HKD1_k127_3129382_1 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000002451 223.0
HKD1_k127_3129382_2 Domain of unknown function (DUF374) K09778 - - 0.000000002177 59.0
HKD1_k127_3146792_0 GXGXG motif - - - 0.0 1300.0
HKD1_k127_3146792_1 Conserved region in glutamate synthase - - - 1.819e-306 943.0
HKD1_k127_3146792_10 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 499.0
HKD1_k127_3146792_11 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 479.0
HKD1_k127_3146792_12 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 452.0
HKD1_k127_3146792_13 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 413.0
HKD1_k127_3146792_14 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 374.0
HKD1_k127_3146792_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008459 263.0
HKD1_k127_3146792_16 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003012 269.0
HKD1_k127_3146792_17 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000001154 228.0
HKD1_k127_3146792_18 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD1_k127_3146792_19 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD1_k127_3146792_2 Glutamate synthase - - - 3.274e-264 822.0
HKD1_k127_3146792_20 ABC transporter, permease protein K02066 - - 0.0000000000000000000000000000000000000000000000000000003984 203.0
HKD1_k127_3146792_21 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000005239 195.0
HKD1_k127_3146792_22 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD1_k127_3146792_23 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000001543 129.0
HKD1_k127_3146792_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000003604 128.0
HKD1_k127_3146792_25 MlaD protein K02067 - - 0.00000000000000000000000004887 119.0
HKD1_k127_3146792_26 protein N-acetylglucosaminyltransferase activity K09667 - 2.4.1.255 0.000000000000000225 90.0
HKD1_k127_3146792_27 YHS domain - - - 0.0000000000005553 73.0
HKD1_k127_3146792_28 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD1_k127_3146792_29 EF-hand, calcium binding motif - - - 0.00001355 51.0
HKD1_k127_3146792_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.336e-242 754.0
HKD1_k127_3146792_4 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 4.16e-221 698.0
HKD1_k127_3146792_5 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 5.749e-216 679.0
HKD1_k127_3146792_6 Ammonium Transporter K03320 - - 3.588e-211 661.0
HKD1_k127_3146792_7 Cro/C1-type HTH DNA-binding domain - - - 1.846e-203 640.0
HKD1_k127_3146792_8 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 593.0
HKD1_k127_3146792_9 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 591.0
HKD1_k127_3176192_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1334.0
HKD1_k127_3176192_1 Beta-lactamase - - - 0.0 1023.0
HKD1_k127_3176192_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 433.0
HKD1_k127_3176192_11 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 365.0
HKD1_k127_3176192_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 349.0
HKD1_k127_3176192_13 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 310.0
HKD1_k127_3176192_14 Transmembrane sensor domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 310.0
HKD1_k127_3176192_15 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 293.0
HKD1_k127_3176192_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005118 292.0
HKD1_k127_3176192_17 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 284.0
HKD1_k127_3176192_18 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001061 281.0
HKD1_k127_3176192_19 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002262 260.0
HKD1_k127_3176192_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 1.924e-212 672.0
HKD1_k127_3176192_20 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
HKD1_k127_3176192_21 COG3634 Alkyl hydroperoxide reductase, large subunit K03387 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
HKD1_k127_3176192_22 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
HKD1_k127_3176192_23 - - - - 0.000000000000000000000000000000000000000000000000000000008648 206.0
HKD1_k127_3176192_25 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000002201 174.0
HKD1_k127_3176192_26 - - - - 0.000000000000000000000000000000001698 130.0
HKD1_k127_3176192_27 - - - - 0.00000000000000000000000000001647 138.0
HKD1_k127_3176192_28 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.0000000000000000000000000003843 114.0
HKD1_k127_3176192_29 - - - - 0.00000000000000000000001842 101.0
HKD1_k127_3176192_3 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 2.298e-203 646.0
HKD1_k127_3176192_30 PFAM Plasmid stabilisation system K06218 - - 0.000000000000000000008151 95.0
HKD1_k127_3176192_31 - - - - 0.0000000000000000001564 95.0
HKD1_k127_3176192_32 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000002025 90.0
HKD1_k127_3176192_33 Plasmid stabilization system - - - 0.000000000000000005534 86.0
HKD1_k127_3176192_34 - - - - 0.00000000000000001251 85.0
HKD1_k127_3176192_35 - - - - 0.0000000000000001071 81.0
HKD1_k127_3176192_36 - - - - 0.00000000000001265 78.0
HKD1_k127_3176192_37 - - - - 0.000000000002353 69.0
HKD1_k127_3176192_38 - - - - 0.000000001233 61.0
HKD1_k127_3176192_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 597.0
HKD1_k127_3176192_40 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0002962 43.0
HKD1_k127_3176192_5 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 562.0
HKD1_k127_3176192_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 563.0
HKD1_k127_3176192_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 522.0
HKD1_k127_3176192_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 478.0
HKD1_k127_3176192_9 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 454.0
HKD1_k127_317676_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 455.0
HKD1_k127_317676_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
HKD1_k127_317676_2 TIGRFAM SagB-type dehydrogenase domain - - - 0.0000000000000000000000000000000000000000000000002964 177.0
HKD1_k127_317676_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000003313 75.0
HKD1_k127_3177614_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 444.0
HKD1_k127_3177614_1 Transposase is116 is110 is902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 289.0
HKD1_k127_3177614_2 Xylose isomerase-like TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000001104 213.0
HKD1_k127_3177614_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000003181 216.0
HKD1_k127_3177614_4 PFAM Lytic K08309 - - 0.00000000000000000000000000000000000000000006762 173.0
HKD1_k127_3177614_5 Putative regulatory protein - - - 0.0000000001443 63.0
HKD1_k127_3177614_6 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000006779 64.0
HKD1_k127_3177614_7 metal-dependent membrane protease K07052 - - 0.0000214 53.0
HKD1_k127_3240761_0 Sulfatase K01130 - 3.1.6.1 2.708e-278 865.0
HKD1_k127_3240761_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 362.0
HKD1_k127_3240761_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 336.0
HKD1_k127_3240761_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
HKD1_k127_3240761_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000003622 211.0
HKD1_k127_3240761_5 SNARE associated Golgi protein - - - 0.00000000000000000000001356 106.0
HKD1_k127_3240761_6 membrane - - - 0.0001643 45.0
HKD1_k127_3278296_0 Major Facilitator Superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HKD1_k127_3278296_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000001365 122.0
HKD1_k127_3278296_2 AntiSigma factor - - - 0.0000008084 59.0
HKD1_k127_3283737_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 587.0
HKD1_k127_3283737_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 374.0
HKD1_k127_3283737_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000009054 53.0
HKD1_k127_3283737_2 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 346.0
HKD1_k127_3283737_3 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
HKD1_k127_3283737_4 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
HKD1_k127_3283737_5 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 293.0
HKD1_k127_3283737_6 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000747 216.0
HKD1_k127_3283737_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000003169 68.0
HKD1_k127_3283737_8 PFAM FecR protein - - - 0.0000000004412 70.0
HKD1_k127_3283737_9 Calcineurin-like phosphoesterase - - - 0.00000005096 64.0
HKD1_k127_3292187_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 474.0
HKD1_k127_3292187_1 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 462.0
HKD1_k127_3292187_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 396.0
HKD1_k127_3292187_3 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
HKD1_k127_3292187_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HKD1_k127_3292187_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000001946 196.0
HKD1_k127_3292187_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000006258 167.0
HKD1_k127_3292187_7 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000001282 159.0
HKD1_k127_3292187_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000002551 129.0
HKD1_k127_3293520_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003541 278.0
HKD1_k127_3293520_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000127 200.0
HKD1_k127_3293520_2 - - - - 0.000000000000000000000000000000000000000000000000000002455 196.0
HKD1_k127_3293520_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000001486 175.0
HKD1_k127_3293520_4 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000007141 183.0
HKD1_k127_3293520_5 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000000000000000000000000000000001043 154.0
HKD1_k127_3293520_6 - - - - 0.00000003009 63.0
HKD1_k127_3293520_7 Glycosyl hydrolase family 48 - - - 0.000002322 60.0
HKD1_k127_3368268_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 332.0
HKD1_k127_3368268_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 313.0
HKD1_k127_3368268_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000007924 244.0
HKD1_k127_3391237_0 Belongs to the ClpX chaperone family - - - 6.429e-246 772.0
HKD1_k127_3391237_1 PFAM Radical SAM K22226 - - 4.295e-196 617.0
HKD1_k127_3391237_10 Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000005642 113.0
HKD1_k127_3391237_12 NhaP-type Na H and K H - - - 0.00000000000000000001579 97.0
HKD1_k127_3391237_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 567.0
HKD1_k127_3391237_3 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
HKD1_k127_3391237_4 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 284.0
HKD1_k127_3391237_5 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003034 252.0
HKD1_k127_3391237_6 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000004284 207.0
HKD1_k127_3391237_7 RDD family - - - 0.00000000000000000000000000000000000001114 151.0
HKD1_k127_3391237_8 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000004621 156.0
HKD1_k127_3391237_9 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000001465 139.0
HKD1_k127_3413915_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1355.0
HKD1_k127_3413915_1 Histidine kinase - - - 2.995e-269 853.0
HKD1_k127_3413915_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008122 236.0
HKD1_k127_3413915_11 Single Cache domain 2 K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
HKD1_k127_3413915_12 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000002043 227.0
HKD1_k127_3413915_13 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000776 198.0
HKD1_k127_3413915_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000001604 171.0
HKD1_k127_3413915_16 transcriptional regulator - - - 0.0000000000000000000000000005258 118.0
HKD1_k127_3413915_17 Beta-galactosidase - - - 0.000000000000000000004844 109.0
HKD1_k127_3413915_19 part of a sulfur-relay system K11179 - - 0.0000000000000000002299 94.0
HKD1_k127_3413915_2 Protein of unknown function, DUF255 K06888 - - 2.299e-209 672.0
HKD1_k127_3413915_20 Sulfate permease K03321 - - 0.000000000000001473 85.0
HKD1_k127_3413915_21 carboxylase K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000004675 75.0
HKD1_k127_3413915_23 Glycine-zipper domain - - - 0.00003742 53.0
HKD1_k127_3413915_24 Glycine zipper - - - 0.0002695 49.0
HKD1_k127_3413915_25 Universal stress protein - - - 0.000525 51.0
HKD1_k127_3413915_3 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 486.0
HKD1_k127_3413915_4 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 479.0
HKD1_k127_3413915_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 344.0
HKD1_k127_3413915_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 341.0
HKD1_k127_3413915_7 Sulfate permease K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
HKD1_k127_3413915_8 Sulfate permease K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 333.0
HKD1_k127_3413915_9 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
HKD1_k127_3463710_0 Response regulator receiver - - - 5.034e-197 623.0
HKD1_k127_3463710_1 PFAM ATP-binding region, ATPase domain protein - - - 1.702e-194 617.0
HKD1_k127_3463710_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000036 240.0
HKD1_k127_3463710_11 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
HKD1_k127_3463710_12 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000002135 163.0
HKD1_k127_3463710_13 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000001204 151.0
HKD1_k127_3463710_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000003208 132.0
HKD1_k127_3463710_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 585.0
HKD1_k127_3463710_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 595.0
HKD1_k127_3463710_4 Type II and III secretion system protein K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 514.0
HKD1_k127_3463710_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HKD1_k127_3463710_6 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
HKD1_k127_3463710_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 317.0
HKD1_k127_3463710_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 315.0
HKD1_k127_3463710_9 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003936 235.0
HKD1_k127_3509978_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1049.0
HKD1_k127_3509978_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 3.935e-313 982.0
HKD1_k127_3509978_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 388.0
HKD1_k127_3509978_11 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 384.0
HKD1_k127_3509978_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 346.0
HKD1_k127_3509978_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 353.0
HKD1_k127_3509978_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 310.0
HKD1_k127_3509978_15 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
HKD1_k127_3509978_16 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 295.0
HKD1_k127_3509978_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
HKD1_k127_3509978_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
HKD1_k127_3509978_19 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003743 258.0
HKD1_k127_3509978_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 4.44e-293 910.0
HKD1_k127_3509978_20 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
HKD1_k127_3509978_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000009715 208.0
HKD1_k127_3509978_22 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000178 203.0
HKD1_k127_3509978_23 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004487 195.0
HKD1_k127_3509978_24 - - - - 0.00000000000000000000000000000000000000000000001047 176.0
HKD1_k127_3509978_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000001339 171.0
HKD1_k127_3509978_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000001452 162.0
HKD1_k127_3509978_27 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.000000000000000000000000000000000000000148 159.0
HKD1_k127_3509978_28 - - - - 0.0000000000000000000000000000000000009018 146.0
HKD1_k127_3509978_29 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000006329 145.0
HKD1_k127_3509978_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.113e-290 902.0
HKD1_k127_3509978_30 YGGT family K02221 - - 0.00000000000000000000000000000005233 130.0
HKD1_k127_3509978_31 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000004946 120.0
HKD1_k127_3509978_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000005092 116.0
HKD1_k127_3509978_33 DUF167 K09131 - - 0.0000000000000000000000008831 106.0
HKD1_k127_3509978_34 regulatory protein, FmdB family - - - 0.0000000000000000000002511 99.0
HKD1_k127_3509978_35 Outer membrane lipoprotein Slp family K07285 - - 0.0000000001139 69.0
HKD1_k127_3509978_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.307e-255 795.0
HKD1_k127_3509978_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 6.645e-201 644.0
HKD1_k127_3509978_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 1.016e-196 619.0
HKD1_k127_3509978_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 542.0
HKD1_k127_3509978_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 412.0
HKD1_k127_3509978_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
HKD1_k127_3520048_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 553.0
HKD1_k127_3520048_1 Secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 529.0
HKD1_k127_3520048_10 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000001817 90.0
HKD1_k127_3520048_11 PFAM TadE family protein - - - 0.00000000006326 69.0
HKD1_k127_3520048_12 type II secretion system protein K12510 - - 0.0000000007007 67.0
HKD1_k127_3520048_13 Flp/Fap pilin component K02651 - - 0.000000003503 60.0
HKD1_k127_3520048_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 457.0
HKD1_k127_3520048_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 428.0
HKD1_k127_3520048_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 302.0
HKD1_k127_3520048_5 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000141 246.0
HKD1_k127_3520048_6 metal-dependent membrane protease - - - 0.000000000000000000000000000000000000000000000000000000000000006689 226.0
HKD1_k127_3520048_7 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000126 228.0
HKD1_k127_3520048_8 Pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000006348 170.0
HKD1_k127_3520048_9 AAA domain K02282 - - 0.000000000000000000000000000000000000004502 160.0
HKD1_k127_3651032_0 Efflux pump membrane transporter K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 464.0
HKD1_k127_3651032_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 457.0
HKD1_k127_3651032_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000001297 89.0
HKD1_k127_394931_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.191e-313 970.0
HKD1_k127_394931_1 Belongs to the TPP enzyme family K04103 - 4.1.1.74 2.881e-241 758.0
HKD1_k127_394931_10 Restriction endonuclease K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 389.0
HKD1_k127_394931_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 381.0
HKD1_k127_394931_12 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 353.0
HKD1_k127_394931_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
HKD1_k127_394931_14 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 320.0
HKD1_k127_394931_15 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 319.0
HKD1_k127_394931_16 Restriction endonuclease K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 310.0
HKD1_k127_394931_17 PFAM import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 293.0
HKD1_k127_394931_18 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HKD1_k127_394931_19 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
HKD1_k127_394931_2 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 1.336e-237 748.0
HKD1_k127_394931_20 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001107 253.0
HKD1_k127_394931_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
HKD1_k127_394931_22 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000002104 189.0
HKD1_k127_394931_23 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000000000000000000000000212 151.0
HKD1_k127_394931_24 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000002533 136.0
HKD1_k127_394931_25 - - - - 0.000000000000000000000000000005797 121.0
HKD1_k127_394931_27 Belongs to the peptidase M50B family - - - 0.00000000000000000000005197 111.0
HKD1_k127_394931_28 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000003401 80.0
HKD1_k127_394931_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 2.841e-212 668.0
HKD1_k127_394931_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.253e-195 619.0
HKD1_k127_394931_5 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 566.0
HKD1_k127_394931_6 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 478.0
HKD1_k127_394931_7 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 478.0
HKD1_k127_394931_8 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 474.0
HKD1_k127_394931_9 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 391.0
HKD1_k127_4022523_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1329.0
HKD1_k127_4022523_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 4.463e-211 688.0
HKD1_k127_4022523_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000001909 70.0
HKD1_k127_4022523_2 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 409.0
HKD1_k127_4022523_3 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 370.0
HKD1_k127_4022523_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 315.0
HKD1_k127_4022523_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 284.0
HKD1_k127_4022523_6 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
HKD1_k127_4022523_7 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000002194 255.0
HKD1_k127_4022523_8 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000006599 219.0
HKD1_k127_4022523_9 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000009928 199.0
HKD1_k127_4023658_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.326e-320 987.0
HKD1_k127_4023658_1 Elongation factor Tu domain 2 K06207 - - 4.058e-309 956.0
HKD1_k127_4023658_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 5.757e-226 709.0
HKD1_k127_4023658_3 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000002559 144.0
HKD1_k127_4023658_4 Transcriptional regulator - - - 0.0000000000000000000005198 100.0
HKD1_k127_4023658_5 Domain of unknown function (DUF4389) - - - 0.0000000000000000001091 93.0
HKD1_k127_4023658_6 Transposase zinc-ribbon domain - - - 0.000000000000003695 76.0
HKD1_k127_4023658_7 ISXO2-like transposase domain - - - 0.000000000000007136 74.0
HKD1_k127_4023658_9 Bacterial SH3 domain homologues - - - 0.0000001177 61.0
HKD1_k127_4046143_0 Thiamine pyrophosphate enzyme, central K01652 - 2.2.1.6 1.414e-288 894.0
HKD1_k127_4046143_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.488e-250 780.0
HKD1_k127_4046143_10 - - - - 0.0000000000000000000000000000002677 133.0
HKD1_k127_4046143_11 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000002764 97.0
HKD1_k127_4046143_13 heat shock protein binding - - - 0.000000000000000004971 87.0
HKD1_k127_4046143_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 562.0
HKD1_k127_4046143_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 332.0
HKD1_k127_4046143_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 302.0
HKD1_k127_4046143_5 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005252 251.0
HKD1_k127_4046143_6 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000002752 236.0
HKD1_k127_4046143_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000002029 216.0
HKD1_k127_4046143_8 - - - - 0.000000000000000000000000000000000000000000000009779 181.0
HKD1_k127_4046143_9 - - - - 0.0000000000000000000000000000000000000000003674 173.0
HKD1_k127_4051202_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1229.0
HKD1_k127_4051202_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 604.0
HKD1_k127_4051202_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 414.0
HKD1_k127_4051202_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000001349 244.0
HKD1_k127_4051202_4 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000128 225.0
HKD1_k127_4051202_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000009341 164.0
HKD1_k127_4051202_6 transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000000000000000000006554 121.0
HKD1_k127_4051202_7 Transposase (IS116 IS110 IS902 family) - - - 0.00002259 49.0
HKD1_k127_4054640_0 molybdopterin cofactor binding K08352 - 1.8.5.5 7.709e-284 890.0
HKD1_k127_4054640_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 535.0
HKD1_k127_4054640_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 346.0
HKD1_k127_4054640_11 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 334.0
HKD1_k127_4054640_12 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 324.0
HKD1_k127_4054640_13 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 330.0
HKD1_k127_4054640_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 314.0
HKD1_k127_4054640_15 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
HKD1_k127_4054640_16 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 311.0
HKD1_k127_4054640_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001247 291.0
HKD1_k127_4054640_18 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008755 278.0
HKD1_k127_4054640_19 Product type r regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HKD1_k127_4054640_2 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 539.0
HKD1_k127_4054640_20 Polysulfide reductase K16294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004172 271.0
HKD1_k127_4054640_21 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005302 265.0
HKD1_k127_4054640_22 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003656 282.0
HKD1_k127_4054640_23 lipoprotein transporter activity K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
HKD1_k127_4054640_24 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
HKD1_k127_4054640_25 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000001308 221.0
HKD1_k127_4054640_26 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002821 230.0
HKD1_k127_4054640_27 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000002417 199.0
HKD1_k127_4054640_28 B12 binding domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000001591 192.0
HKD1_k127_4054640_29 response regulator, receiver K02485 - - 0.0000000000000000000000000000000000000000000000000003846 187.0
HKD1_k127_4054640_3 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 487.0
HKD1_k127_4054640_31 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000008336 168.0
HKD1_k127_4054640_32 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000003545 114.0
HKD1_k127_4054640_34 AAA domain K07028 - - 0.00000000000000000000000003656 115.0
HKD1_k127_4054640_35 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.0000000000000000000001199 105.0
HKD1_k127_4054640_36 - - - - 0.0000000000000003216 82.0
HKD1_k127_4054640_37 - - - - 0.000000000000003568 84.0
HKD1_k127_4054640_38 Rhodanese Homology Domain - - - 0.00000002091 64.0
HKD1_k127_4054640_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 426.0
HKD1_k127_4054640_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
HKD1_k127_4054640_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 372.0
HKD1_k127_4054640_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 374.0
HKD1_k127_4054640_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 362.0
HKD1_k127_4054640_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 331.0
HKD1_k127_4129276_0 Citrate lyase, alpha subunit (CitF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 316.0
HKD1_k127_4129276_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000258 270.0
HKD1_k127_4129276_2 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000000000000000000000000000000000002253 224.0
HKD1_k127_4129276_3 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000003131 105.0
HKD1_k127_4130134_0 PFAM pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0 1135.0
HKD1_k127_4130134_1 Cytochrome c554 and c-prime - - - 7.278e-295 926.0
HKD1_k127_4130134_10 PP-loop superfamily ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 420.0
HKD1_k127_4130134_11 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
HKD1_k127_4130134_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
HKD1_k127_4130134_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 372.0
HKD1_k127_4130134_14 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 332.0
HKD1_k127_4130134_15 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 306.0
HKD1_k127_4130134_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
HKD1_k127_4130134_17 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
HKD1_k127_4130134_18 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008156 258.0
HKD1_k127_4130134_19 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 256.0
HKD1_k127_4130134_2 Histidine kinase - - - 7.48e-216 685.0
HKD1_k127_4130134_20 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004509 241.0
HKD1_k127_4130134_21 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000001507 208.0
HKD1_k127_4130134_22 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000003467 175.0
HKD1_k127_4130134_23 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000001798 164.0
HKD1_k127_4130134_24 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000001691 159.0
HKD1_k127_4130134_25 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000009081 152.0
HKD1_k127_4130134_26 Protein of unknown function DUF134 - - - 0.000000000000000000000000000000000000004409 154.0
HKD1_k127_4130134_27 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000001909 153.0
HKD1_k127_4130134_28 transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000008865 102.0
HKD1_k127_4130134_29 phosphorelay signal transduction system - - - 0.00000000000000000000001593 104.0
HKD1_k127_4130134_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 2.528e-207 651.0
HKD1_k127_4130134_30 protein with SCP PR1 domains - - - 0.00000000000000000000007801 105.0
HKD1_k127_4130134_32 - - - - 0.0000001973 57.0
HKD1_k127_4130134_33 gas vesicle protein - - - 0.00006949 48.0
HKD1_k127_4130134_34 LytTr DNA-binding domain - - - 0.0003772 48.0
HKD1_k127_4130134_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.33e-204 644.0
HKD1_k127_4130134_5 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 2.782e-199 631.0
HKD1_k127_4130134_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 513.0
HKD1_k127_4130134_7 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 511.0
HKD1_k127_4130134_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 471.0
HKD1_k127_4130134_9 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 458.0
HKD1_k127_4134930_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 6.126e-222 696.0
HKD1_k127_4134930_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 427.0
HKD1_k127_4134930_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 416.0
HKD1_k127_4134930_3 ErfK YbiS YcfS YnhG family protein K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
HKD1_k127_4137290_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0 1320.0
HKD1_k127_4137290_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.644e-268 836.0
HKD1_k127_4137290_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 2.185e-201 633.0
HKD1_k127_4137290_3 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 590.0
HKD1_k127_4137290_4 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 572.0
HKD1_k127_4137290_5 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 311.0
HKD1_k127_4137290_6 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003702 266.0
HKD1_k127_4137290_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 250.0
HKD1_k127_4137290_8 PFAM Cupin 2 conserved barrel domain protein - - - 0.00006113 49.0
HKD1_k127_4149208_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1137.0
HKD1_k127_4149208_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 577.0
HKD1_k127_4149208_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 487.0
HKD1_k127_4149208_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
HKD1_k127_4149208_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 389.0
HKD1_k127_4149208_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 291.0
HKD1_k127_4149208_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000004233 196.0
HKD1_k127_4149208_7 unfolded protein binding K06142 - - 0.000000000000000000000000002174 117.0
HKD1_k127_4149208_8 ISXO2-like transposase domain - - - 0.00000000000000003471 82.0
HKD1_k127_4179042_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.207e-223 696.0
HKD1_k127_4179042_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 451.0
HKD1_k127_4179042_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD1_k127_4179042_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005402 211.0
HKD1_k127_4179042_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001188 194.0
HKD1_k127_4179042_13 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000004183 181.0
HKD1_k127_4179042_14 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000006108 167.0
HKD1_k127_4179042_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003503 159.0
HKD1_k127_4179042_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001251 155.0
HKD1_k127_4179042_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000005581 154.0
HKD1_k127_4179042_18 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000037 139.0
HKD1_k127_4179042_19 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000004319 138.0
HKD1_k127_4179042_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 336.0
HKD1_k127_4179042_20 DoxX K15977 - - 0.000000000000000000000000000000005083 132.0
HKD1_k127_4179042_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003882 123.0
HKD1_k127_4179042_22 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000004066 113.0
HKD1_k127_4179042_23 PFAM ribosomal protein L30 K02907 - - 0.00000000000000000302 85.0
HKD1_k127_4179042_24 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000006823 71.0
HKD1_k127_4179042_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 331.0
HKD1_k127_4179042_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 296.0
HKD1_k127_4179042_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 287.0
HKD1_k127_4179042_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001804 279.0
HKD1_k127_4179042_7 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
HKD1_k127_4179042_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005076 241.0
HKD1_k127_4179042_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001067 224.0
HKD1_k127_4219195_0 4Fe-4S dicluster domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.729e-264 818.0
HKD1_k127_4219195_1 Elongation factor Tu domain 2 K02355 - - 4.832e-252 795.0
HKD1_k127_4219195_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
HKD1_k127_4219195_11 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 367.0
HKD1_k127_4219195_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 332.0
HKD1_k127_4219195_13 nitrate reductase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 295.0
HKD1_k127_4219195_14 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 295.0
HKD1_k127_4219195_15 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
HKD1_k127_4219195_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001048 279.0
HKD1_k127_4219195_17 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
HKD1_k127_4219195_18 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004987 248.0
HKD1_k127_4219195_19 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
HKD1_k127_4219195_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 604.0
HKD1_k127_4219195_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HKD1_k127_4219195_21 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
HKD1_k127_4219195_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K16079,K22110 - - 0.0000000000000000000000000000000000000000000000000000000001024 214.0
HKD1_k127_4219195_23 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000001369 209.0
HKD1_k127_4219195_24 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000009154 205.0
HKD1_k127_4219195_25 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000002694 188.0
HKD1_k127_4219195_26 MOSC domain - - - 0.00000000000000000000000000000000000000000000000007595 183.0
HKD1_k127_4219195_27 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000001901 178.0
HKD1_k127_4219195_28 Transcriptional regulator - - - 0.00000000000000000000000000000000000000307 159.0
HKD1_k127_4219195_29 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000003627 146.0
HKD1_k127_4219195_3 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 581.0
HKD1_k127_4219195_30 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000004298 128.0
HKD1_k127_4219195_31 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000006441 123.0
HKD1_k127_4219195_32 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000000008277 117.0
HKD1_k127_4219195_33 PFAM CBS domain containing protein - - - 0.00000000000000000000000002295 119.0
HKD1_k127_4219195_34 Sulfurtransferase TusA - - - 0.0000000000000000003501 89.0
HKD1_k127_4219195_35 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000002466 84.0
HKD1_k127_4219195_37 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000008669 78.0
HKD1_k127_4219195_39 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001775 61.0
HKD1_k127_4219195_4 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 557.0
HKD1_k127_4219195_40 Tetratricopeptide repeat-like domain - - - 0.00003094 54.0
HKD1_k127_4219195_5 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 525.0
HKD1_k127_4219195_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 445.0
HKD1_k127_4219195_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD1_k127_4219195_8 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 401.0
HKD1_k127_4219195_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 404.0
HKD1_k127_4224209_0 DEAD DEAH box helicase K06877 - - 0.0 1279.0
HKD1_k127_4224209_1 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1242.0
HKD1_k127_4224209_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 489.0
HKD1_k127_4224209_11 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 479.0
HKD1_k127_4224209_12 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 474.0
HKD1_k127_4224209_13 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 442.0
HKD1_k127_4224209_14 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 424.0
HKD1_k127_4224209_15 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 382.0
HKD1_k127_4224209_17 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 354.0
HKD1_k127_4224209_18 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 347.0
HKD1_k127_4224209_19 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 331.0
HKD1_k127_4224209_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.067e-211 661.0
HKD1_k127_4224209_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 312.0
HKD1_k127_4224209_21 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 322.0
HKD1_k127_4224209_22 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 305.0
HKD1_k127_4224209_23 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
HKD1_k127_4224209_24 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 232.0
HKD1_k127_4224209_25 SMART Transcription regulator, AsnC-type - - - 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
HKD1_k127_4224209_26 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000009654 209.0
HKD1_k127_4224209_27 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001254 199.0
HKD1_k127_4224209_28 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000013 188.0
HKD1_k127_4224209_29 AMP binding - - - 0.0000000000000000000000000000000000000000000000001766 180.0
HKD1_k127_4224209_3 Belongs to the CarA family K01956 - 6.3.5.5 3.402e-206 645.0
HKD1_k127_4224209_30 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001134 181.0
HKD1_k127_4224209_31 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000002201 176.0
HKD1_k127_4224209_32 FecR protein - - - 0.00000000000000000000000000000001121 138.0
HKD1_k127_4224209_33 peroxiredoxin activity - - - 0.00000000000000000000000000000001342 134.0
HKD1_k127_4224209_34 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001205 119.0
HKD1_k127_4224209_35 - - - - 0.00000000000000000000000000005437 117.0
HKD1_k127_4224209_36 Right handed beta helix region - - - 0.00000000000000000000000000009498 126.0
HKD1_k127_4224209_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000007058 114.0
HKD1_k127_4224209_39 Protein of unknown function DUF86 - - - 0.000000000000000000000000004353 114.0
HKD1_k127_4224209_4 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 590.0
HKD1_k127_4224209_40 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000000005867 109.0
HKD1_k127_4224209_41 Protein of unknown function (DUF2939) - - - 0.0000000000000000000000003736 112.0
HKD1_k127_4224209_42 peroxiredoxin activity - - - 0.000000000000000000000001909 110.0
HKD1_k127_4224209_43 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000008162 99.0
HKD1_k127_4224209_44 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000004866 90.0
HKD1_k127_4224209_45 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000009136 91.0
HKD1_k127_4224209_46 - - - - 0.0000000000000007068 82.0
HKD1_k127_4224209_5 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 588.0
HKD1_k127_4224209_6 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 593.0
HKD1_k127_4224209_7 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 582.0
HKD1_k127_4224209_8 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 539.0
HKD1_k127_4224209_9 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 527.0
HKD1_k127_4282674_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 499.0
HKD1_k127_4282674_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 357.0
HKD1_k127_4282674_2 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 349.0
HKD1_k127_4282674_3 MlaD protein K02067 - - 0.000000000000001496 78.0
HKD1_k127_4308804_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1142.0
HKD1_k127_4308804_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.48e-269 841.0
HKD1_k127_4308804_10 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
HKD1_k127_4308804_11 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 412.0
HKD1_k127_4308804_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 389.0
HKD1_k127_4308804_13 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 378.0
HKD1_k127_4308804_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 310.0
HKD1_k127_4308804_15 photoreceptor activity K07315,K20971 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
HKD1_k127_4308804_16 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 299.0
HKD1_k127_4308804_17 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 293.0
HKD1_k127_4308804_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000984 285.0
HKD1_k127_4308804_19 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
HKD1_k127_4308804_2 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.833e-233 735.0
HKD1_k127_4308804_20 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000151 231.0
HKD1_k127_4308804_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001473 224.0
HKD1_k127_4308804_22 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000946 212.0
HKD1_k127_4308804_23 CGGC - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
HKD1_k127_4308804_24 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000004747 195.0
HKD1_k127_4308804_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000002218 187.0
HKD1_k127_4308804_26 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002672 185.0
HKD1_k127_4308804_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000001274 188.0
HKD1_k127_4308804_28 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000001205 177.0
HKD1_k127_4308804_29 - - - - 0.000000000000000000000000000000000000000000238 162.0
HKD1_k127_4308804_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 617.0
HKD1_k127_4308804_30 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000003132 147.0
HKD1_k127_4308804_31 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000001571 141.0
HKD1_k127_4308804_32 regulatory protein, FmdB family - - - 0.000000000000000000000000000000000001808 143.0
HKD1_k127_4308804_33 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000001596 143.0
HKD1_k127_4308804_35 Rubrerythrin - - - 0.0000000000000000000000000005849 124.0
HKD1_k127_4308804_36 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001104 117.0
HKD1_k127_4308804_38 Transcriptional regulator - - - 0.000000000000000000000008611 105.0
HKD1_k127_4308804_39 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000003144 102.0
HKD1_k127_4308804_4 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 614.0
HKD1_k127_4308804_40 - - - - 0.0000000000000000000001335 103.0
HKD1_k127_4308804_41 ATP-independent chaperone mediated protein folding K07803 - - 0.000000000000000002248 93.0
HKD1_k127_4308804_42 - - - - 0.000000000000000002792 87.0
HKD1_k127_4308804_43 snoRNA binding - - - 0.000000000000001707 79.0
HKD1_k127_4308804_44 competence protein - - - 0.00000000000001841 81.0
HKD1_k127_4308804_45 peptidyl-tyrosine sulfation - - - 0.00000000000002373 82.0
HKD1_k127_4308804_47 SH3, type 3 domain protein - - - 0.00000001436 65.0
HKD1_k127_4308804_48 COG2801 Transposase and inactivated derivatives - - - 0.00000004304 55.0
HKD1_k127_4308804_49 Putative zinc-finger - - - 0.0000008623 56.0
HKD1_k127_4308804_5 PFAM Peptidase M20 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 516.0
HKD1_k127_4308804_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 497.0
HKD1_k127_4308804_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 466.0
HKD1_k127_4308804_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 454.0
HKD1_k127_4308804_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 443.0
HKD1_k127_4412460_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.096e-210 659.0
HKD1_k127_4412460_1 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003483 241.0
HKD1_k127_4412460_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000001808 220.0
HKD1_k127_4539736_0 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
HKD1_k127_4539736_1 COGs COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000107 167.0
HKD1_k127_4539736_2 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000005294 113.0
HKD1_k127_4552892_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 601.0
HKD1_k127_4552892_1 dihydroorotate dehydrogenase activity K00226,K00254,K02823,K17828 - 1.3.1.14,1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HKD1_k127_4552892_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 316.0
HKD1_k127_4552892_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
HKD1_k127_4552892_4 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
HKD1_k127_4552892_5 PFAM UBA THIF-type NAD FAD binding - - - 0.0000000000000000000000000000000000000000000000003594 187.0
HKD1_k127_4552892_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000004059 72.0
HKD1_k127_4552892_7 Mut7-C ubiquitin - - - 0.00000000241 59.0
HKD1_k127_45724_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 509.0
HKD1_k127_45724_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 494.0
HKD1_k127_45724_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 374.0
HKD1_k127_45724_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 304.0
HKD1_k127_45724_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002821 274.0
HKD1_k127_45724_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
HKD1_k127_45724_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000003429 206.0
HKD1_k127_45724_7 - - - - 0.00000000000000000000000000000001001 130.0
HKD1_k127_45724_8 mRNA binding - - - 0.0000000000000000000000000002416 115.0
HKD1_k127_45724_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000007758 90.0
HKD1_k127_4595133_0 tRNA synthetases class I (W and Y) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 594.0
HKD1_k127_4595133_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
HKD1_k127_4651522_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.592e-208 666.0
HKD1_k127_4651522_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
HKD1_k127_4651522_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000002808 188.0
HKD1_k127_4651522_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000008223 168.0
HKD1_k127_4651522_4 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000001451 159.0
HKD1_k127_4651522_5 Belongs to the UPF0102 family K07460 - - 0.000000000000000006066 86.0
HKD1_k127_4651522_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.00000003243 59.0
HKD1_k127_4719498_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1073.0
HKD1_k127_4719498_1 Heat shock 70 kDa protein K04043 - - 0.0 1009.0
HKD1_k127_4719498_11 YHS domain protein - - - 0.0000000000000000000000000000004298 128.0
HKD1_k127_4719498_12 - - - - 0.00000000000000000000002872 102.0
HKD1_k127_4719498_14 Helix-turn-helix XRE-family like proteins K07334,K21498 - - 0.00000000000000000002906 93.0
HKD1_k127_4719498_16 Glycine-zipper domain - - - 0.0000000000000000369 83.0
HKD1_k127_4719498_17 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000001892 52.0
HKD1_k127_4719498_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 539.0
HKD1_k127_4719498_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 448.0
HKD1_k127_4719498_4 PFAM Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HKD1_k127_4719498_5 PFAM Extracellular ligand-binding receptor K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 439.0
HKD1_k127_4719498_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HKD1_k127_4719498_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000297 197.0
HKD1_k127_4719498_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000001321 171.0
HKD1_k127_4719498_9 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000663 156.0
HKD1_k127_472766_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.003e-224 703.0
HKD1_k127_472766_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 532.0
HKD1_k127_472766_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003442 266.0
HKD1_k127_472766_3 TPR Domain containing protein K12600 - - 0.000000000000000006761 92.0
HKD1_k127_472766_4 - - - - 0.000000512 61.0
HKD1_k127_472766_5 PQQ-like domain K00117 - 1.1.5.2 0.00002144 51.0
HKD1_k127_472766_7 SMART Tetratricopeptide - - - 0.00008125 51.0
HKD1_k127_4750986_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0 1103.0
HKD1_k127_4750986_1 Methylmalonyl-CoA mutase - - - 1.037e-198 634.0
HKD1_k127_4750986_10 TIGRFAM Cytochrome o ubiquinol oxidase subunit IV K02300 - - 0.0000000000000000000000000000000000003655 142.0
HKD1_k127_4750986_11 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.0000000000000000000000000000001923 128.0
HKD1_k127_4750986_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 449.0
HKD1_k127_4750986_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 438.0
HKD1_k127_4750986_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 408.0
HKD1_k127_4750986_5 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 363.0
HKD1_k127_4750986_6 NmrA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 324.0
HKD1_k127_4750986_7 cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 318.0
HKD1_k127_4750986_8 PFAM metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003967 290.0
HKD1_k127_4750986_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
HKD1_k127_4804517_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 486.0
HKD1_k127_4804517_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
HKD1_k127_4804517_10 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000002462 52.0
HKD1_k127_4804517_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 380.0
HKD1_k127_4804517_3 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 335.0
HKD1_k127_4804517_4 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 293.0
HKD1_k127_4804517_5 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
HKD1_k127_4804517_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
HKD1_k127_4804517_7 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000001297 219.0
HKD1_k127_4804517_8 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000000000000001036 165.0
HKD1_k127_4822667_0 Belongs to the glycosyl hydrolase 57 family - - - 1.626e-274 867.0
HKD1_k127_4822667_1 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 561.0
HKD1_k127_4822667_10 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000001058 184.0
HKD1_k127_4822667_11 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000001796 148.0
HKD1_k127_4822667_12 Cyclophilin-like K09143 - - 0.000000000000000000000000000002231 124.0
HKD1_k127_4822667_13 TIGRFAM regulatory protein, FmdB - - - 0.0000000000000000000000000434 109.0
HKD1_k127_4822667_14 - - - - 0.0000000000000000000001124 105.0
HKD1_k127_4822667_15 - - - - 0.0001986 52.0
HKD1_k127_4822667_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 474.0
HKD1_k127_4822667_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 462.0
HKD1_k127_4822667_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 365.0
HKD1_k127_4822667_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 356.0
HKD1_k127_4822667_6 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 333.0
HKD1_k127_4822667_7 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
HKD1_k127_4822667_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
HKD1_k127_4822667_9 ThiF family K03148,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000001123 249.0
HKD1_k127_4823205_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.778e-290 908.0
HKD1_k127_4823205_1 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 8.143e-248 794.0
HKD1_k127_4823205_10 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
HKD1_k127_4823205_11 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002258 275.0
HKD1_k127_4823205_12 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
HKD1_k127_4823205_13 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
HKD1_k127_4823205_14 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
HKD1_k127_4823205_15 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004021 241.0
HKD1_k127_4823205_16 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000003409 219.0
HKD1_k127_4823205_17 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
HKD1_k127_4823205_18 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
HKD1_k127_4823205_19 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000000000000000004124 214.0
HKD1_k127_4823205_2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 4.646e-244 762.0
HKD1_k127_4823205_20 PFAM NLP P60 protein K19223 - - 0.0000000000000000000000000000000000000000002138 169.0
HKD1_k127_4823205_22 - - - - 0.000000000000000000000000000000000000001524 152.0
HKD1_k127_4823205_23 - - - - 0.00000000000000000000000000000000003617 140.0
HKD1_k127_4823205_24 - - - - 0.00000000002054 70.0
HKD1_k127_4823205_25 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD1_k127_4823205_26 cheY-homologous receiver domain - - - 0.0001179 51.0
HKD1_k127_4823205_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 554.0
HKD1_k127_4823205_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 465.0
HKD1_k127_4823205_5 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 406.0
HKD1_k127_4823205_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 377.0
HKD1_k127_4823205_7 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 357.0
HKD1_k127_4823205_8 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 363.0
HKD1_k127_4823205_9 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 329.0
HKD1_k127_4847827_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 317.0
HKD1_k127_4847827_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 304.0
HKD1_k127_4847827_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000007427 210.0
HKD1_k127_4847827_3 Vibrio cholerae RfbT protein - - - 0.000000000000000000000003279 113.0
HKD1_k127_4847827_4 zinc ion binding K06204 - - 0.000000000000000000000008785 101.0
HKD1_k127_4892494_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000001397 186.0
HKD1_k127_4905618_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1116.0
HKD1_k127_4905618_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 581.0
HKD1_k127_4905618_10 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000000000000000000000000000000000000000000000000000004337 205.0
HKD1_k127_4905618_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000002442 185.0
HKD1_k127_4905618_12 - - - - 0.000000000000000000000000000000006082 131.0
HKD1_k127_4905618_13 Sh3 type 3 domain protein K03642,K07184 - - 0.00000000000000000001068 101.0
HKD1_k127_4905618_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 462.0
HKD1_k127_4905618_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 458.0
HKD1_k127_4905618_4 reductase alpha subunit K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 372.0
HKD1_k127_4905618_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
HKD1_k127_4905618_6 reductase, beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 283.0
HKD1_k127_4905618_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001921 283.0
HKD1_k127_4905618_8 Sulfate ABC transporter periplasmic sulfate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000001175 221.0
HKD1_k127_4905618_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004014 210.0
HKD1_k127_4932448_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.673e-310 966.0
HKD1_k127_4932448_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.632e-245 768.0
HKD1_k127_4932448_10 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000006715 102.0
HKD1_k127_4932448_13 PFAM Integrase catalytic region K07497 - - 0.0007497 46.0
HKD1_k127_4932448_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.819e-203 638.0
HKD1_k127_4932448_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 381.0
HKD1_k127_4932448_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 303.0
HKD1_k127_4932448_5 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000004432 221.0
HKD1_k127_4932448_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000001011 201.0
HKD1_k127_4932448_7 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000001803 144.0
HKD1_k127_4932448_8 Thymidylate synthase K00560 - 2.1.1.45 0.0000000000000000000000000000000001962 143.0
HKD1_k127_4945438_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 561.0
HKD1_k127_4945438_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
HKD1_k127_4945438_10 DHH family K07462 - - 0.00000000004232 64.0
HKD1_k127_4945438_12 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001591 47.0
HKD1_k127_4945438_2 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 293.0
HKD1_k127_4945438_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 262.0
HKD1_k127_4945438_4 lyase activity - - - 0.000000000000000000000000000000000000000000000000000003941 202.0
HKD1_k127_4945438_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000006934 190.0
HKD1_k127_4945438_6 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000278 179.0
HKD1_k127_4945438_7 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000116 160.0
HKD1_k127_4945438_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000001764 162.0
HKD1_k127_4945438_9 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000007911 149.0
HKD1_k127_507379_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5e-323 1002.0
HKD1_k127_507379_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004622 257.0
HKD1_k127_5096069_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 571.0
HKD1_k127_5096069_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 357.0
HKD1_k127_5096069_10 Phage integrase family - - - 0.0002152 45.0
HKD1_k127_5096069_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000007648 214.0
HKD1_k127_5096069_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000003738 179.0
HKD1_k127_5096069_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000001417 164.0
HKD1_k127_5096069_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000003456 168.0
HKD1_k127_5096069_6 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000002919 151.0
HKD1_k127_5096069_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000008323 145.0
HKD1_k127_5096069_8 Cysteine-rich secretory protein family - - - 0.0000000000000000000000404 106.0
HKD1_k127_5096069_9 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000004408 51.0
HKD1_k127_5117778_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 613.0
HKD1_k127_5117778_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 515.0
HKD1_k127_5117778_2 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 438.0
HKD1_k127_5117778_3 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 430.0
HKD1_k127_5117778_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 386.0
HKD1_k127_5117778_5 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 330.0
HKD1_k127_5117778_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 288.0
HKD1_k127_5117778_7 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000001442 169.0
HKD1_k127_5117778_8 - - - - 0.000000059 61.0
HKD1_k127_5117778_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000002148 59.0
HKD1_k127_5123505_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000238 253.0
HKD1_k127_5123505_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000009479 128.0
HKD1_k127_5123505_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000005454 71.0
HKD1_k127_5164206_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 9.274e-318 993.0
HKD1_k127_5164206_1 Histidine kinase K07709 - 2.7.13.3 9.662e-259 819.0
HKD1_k127_5164206_10 Protein of unknown function (DUF2905) - - - 0.00000000000000000006234 90.0
HKD1_k127_5164206_11 Yip1 domain - - - 0.00000000004453 72.0
HKD1_k127_5164206_2 Elongation factor Tu domain 2 K03833 - - 1.465e-252 793.0
HKD1_k127_5164206_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.945e-204 646.0
HKD1_k127_5164206_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 546.0
HKD1_k127_5164206_5 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 472.0
HKD1_k127_5164206_6 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 291.0
HKD1_k127_5164206_7 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000001317 193.0
HKD1_k127_5164206_8 - - - - 0.00000000000000000000000000000000000000003262 155.0
HKD1_k127_5164206_9 Bacterial PH domain - - - 0.000000000000000000000003662 107.0
HKD1_k127_5168407_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0 1050.0
HKD1_k127_5168407_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1049.0
HKD1_k127_5168407_10 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 1.153e-199 636.0
HKD1_k127_5168407_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 586.0
HKD1_k127_5168407_12 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 557.0
HKD1_k127_5168407_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 534.0
HKD1_k127_5168407_14 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 533.0
HKD1_k127_5168407_15 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 454.0
HKD1_k127_5168407_16 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 441.0
HKD1_k127_5168407_17 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 377.0
HKD1_k127_5168407_18 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
HKD1_k127_5168407_19 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 344.0
HKD1_k127_5168407_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.793e-301 935.0
HKD1_k127_5168407_20 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 326.0
HKD1_k127_5168407_21 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
HKD1_k127_5168407_22 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HKD1_k127_5168407_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
HKD1_k127_5168407_24 DisA bacterial checkpoint controller nucleotide-binding K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD1_k127_5168407_25 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
HKD1_k127_5168407_26 Domain of unknown function (DUF4881) - - - 0.000000000000000000000000000000000000000000000000000000000000000000393 235.0
HKD1_k127_5168407_27 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000004859 217.0
HKD1_k127_5168407_28 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000434 181.0
HKD1_k127_5168407_29 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000005454 171.0
HKD1_k127_5168407_3 Belongs to the helicase family. UvrD subfamily - - - 1.228e-293 937.0
HKD1_k127_5168407_30 - - - - 0.000000000000000000000000000000000000000000001058 177.0
HKD1_k127_5168407_31 Universal stress protein - - - 0.000000000000000000000000000000000000000000007397 166.0
HKD1_k127_5168407_32 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000189 150.0
HKD1_k127_5168407_33 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000001048 144.0
HKD1_k127_5168407_34 HNH nucleases - - - 0.000000000000000000000000000000000000252 141.0
HKD1_k127_5168407_35 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000001808 154.0
HKD1_k127_5168407_36 cellular response to heat K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000222 144.0
HKD1_k127_5168407_37 - - - - 0.000000000000000000000000000000001299 143.0
HKD1_k127_5168407_38 - - - - 0.0000000000000000000000000000006039 125.0
HKD1_k127_5168407_39 PFAM response regulator receiver - - - 0.000000000000000000000000000003886 125.0
HKD1_k127_5168407_4 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 8.945e-280 884.0
HKD1_k127_5168407_40 - - - - 0.000000000000000000000000000004425 128.0
HKD1_k127_5168407_41 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000271 121.0
HKD1_k127_5168407_42 Nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000006725 114.0
HKD1_k127_5168407_44 YHS domain - - - 0.0000000000000000000006194 97.0
HKD1_k127_5168407_45 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000007678 101.0
HKD1_k127_5168407_46 PFAM YbbR family protein - - - 0.000000000000001639 87.0
HKD1_k127_5168407_48 PFAM Colicin V production protein K03558 - - 0.000000000008288 73.0
HKD1_k127_5168407_49 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000007591 74.0
HKD1_k127_5168407_5 SMART Elongator protein 3 MiaB NifB - - - 1.591e-260 816.0
HKD1_k127_5168407_50 - - - - 0.000003566 55.0
HKD1_k127_5168407_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.906e-230 728.0
HKD1_k127_5168407_7 ATP-dependent nuclease subunit B-like - - - 1.454e-227 734.0
HKD1_k127_5168407_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 4.531e-209 677.0
HKD1_k127_5168407_9 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 4.128e-207 657.0
HKD1_k127_519009_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.466e-197 627.0
HKD1_k127_519009_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 403.0
HKD1_k127_519009_2 cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000001085 186.0
HKD1_k127_519009_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000004255 105.0
HKD1_k127_519009_4 - - - - 0.0000000000000003729 85.0
HKD1_k127_519009_5 transposition, DNA-mediated - - - 0.00000000002664 64.0
HKD1_k127_5203921_0 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1269.0
HKD1_k127_5203921_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 2.562e-218 687.0
HKD1_k127_5203921_10 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000006362 105.0
HKD1_k127_5203921_11 FAD dependent oxidoreductase - - - 0.0000000000000000000004936 101.0
HKD1_k127_5203921_12 TIGRFAM DNA binding domain, excisionase family K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000005917 66.0
HKD1_k127_5203921_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.00000002535 55.0
HKD1_k127_5203921_2 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 477.0
HKD1_k127_5203921_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 463.0
HKD1_k127_5203921_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 433.0
HKD1_k127_5203921_5 cell adhesion involved in biofilm formation K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 376.0
HKD1_k127_5203921_6 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 295.0
HKD1_k127_5203921_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.0000000000000000000000000000000000000002677 156.0
HKD1_k127_5203921_8 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000001711 126.0
HKD1_k127_5203921_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000004248 119.0
HKD1_k127_5206809_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.299e-291 902.0
HKD1_k127_5206809_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.424e-248 780.0
HKD1_k127_5206809_2 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 375.0
HKD1_k127_5206809_3 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
HKD1_k127_5206809_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000006925 203.0
HKD1_k127_5206809_5 OstA-like protein K09774 - - 0.000000000000000000000000000000000001588 147.0
HKD1_k127_5206809_6 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000000003376 92.0
HKD1_k127_5206809_7 Mut7-C ubiquitin - - - 0.00000000000002105 76.0
HKD1_k127_5206809_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000006471 73.0
HKD1_k127_5257516_0 PFAM alpha amylase, catalytic K06044 - 5.4.99.15 0.0 1094.0
HKD1_k127_5257516_1 Domain of unknown function (DUF3536) - - - 0.0 1031.0
HKD1_k127_5257516_10 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 315.0
HKD1_k127_5257516_11 Fructose-bisphosphate aldolase class K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 304.0
HKD1_k127_5257516_12 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001942 252.0
HKD1_k127_5257516_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000002079 243.0
HKD1_k127_5257516_14 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000005069 225.0
HKD1_k127_5257516_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000245 193.0
HKD1_k127_5257516_16 - - - - 0.00000000000000000000000000000000000000000000000001364 187.0
HKD1_k127_5257516_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000002031 172.0
HKD1_k127_5257516_18 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001027 151.0
HKD1_k127_5257516_19 NusB family K03625 - - 0.00000000000000000000000000000000000001304 148.0
HKD1_k127_5257516_2 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 1.815e-237 749.0
HKD1_k127_5257516_20 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001205 119.0
HKD1_k127_5257516_21 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000001005 120.0
HKD1_k127_5257516_22 Predicted membrane protein (DUF2232) - - - 0.00000000000000000000000001229 121.0
HKD1_k127_5257516_23 LysE type translocator - - - 0.000000000000000000000001486 104.0
HKD1_k127_5257516_24 Beta-1,3-glucanase - - - 0.00000000000000000000008308 112.0
HKD1_k127_5257516_25 Belongs to the sulfur carrier protein TusA family - - - 0.00000005125 57.0
HKD1_k127_5257516_26 - - - - 0.00006767 49.0
HKD1_k127_5257516_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.191e-210 663.0
HKD1_k127_5257516_4 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 8.275e-199 625.0
HKD1_k127_5257516_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 564.0
HKD1_k127_5257516_6 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 566.0
HKD1_k127_5257516_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 452.0
HKD1_k127_5257516_8 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 446.0
HKD1_k127_5257516_9 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 336.0
HKD1_k127_5258810_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.075e-279 864.0
HKD1_k127_5258810_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.452e-276 851.0
HKD1_k127_5258810_10 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000000000000005762 136.0
HKD1_k127_5258810_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000005637 132.0
HKD1_k127_5258810_12 Protein of unknown function DUF86 - - - 0.00000000000000000000000000005299 119.0
HKD1_k127_5258810_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
HKD1_k127_5258810_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 411.0
HKD1_k127_5258810_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 301.0
HKD1_k127_5258810_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
HKD1_k127_5258810_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
HKD1_k127_5258810_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000001617 188.0
HKD1_k127_5258810_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000002892 186.0
HKD1_k127_5258810_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000006736 158.0
HKD1_k127_5317170_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K19594 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 377.0
HKD1_k127_5317170_1 cell adhesion involved in biofilm formation K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 365.0
HKD1_k127_5322550_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
HKD1_k127_5322550_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001309 280.0
HKD1_k127_5322550_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
HKD1_k127_5322550_3 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000000000000000000000000000000000004009 237.0
HKD1_k127_5373567_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K19694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 341.0
HKD1_k127_5373567_1 Sensory domain found in PocR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 271.0
HKD1_k127_5388644_0 Amino acid permease - - - 8.077e-254 796.0
HKD1_k127_5388644_1 Amino acid permease - - - 1.358e-237 750.0
HKD1_k127_5388644_10 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 338.0
HKD1_k127_5388644_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HKD1_k127_5388644_12 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 289.0
HKD1_k127_5388644_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 277.0
HKD1_k127_5388644_14 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
HKD1_k127_5388644_15 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000593 173.0
HKD1_k127_5388644_16 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000001002 141.0
HKD1_k127_5388644_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000002722 120.0
HKD1_k127_5388644_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 4.155e-231 729.0
HKD1_k127_5388644_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 467.0
HKD1_k127_5388644_4 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 416.0
HKD1_k127_5388644_5 transport system permease K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 411.0
HKD1_k127_5388644_6 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 400.0
HKD1_k127_5388644_7 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 392.0
HKD1_k127_5388644_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 385.0
HKD1_k127_5388644_9 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 368.0
HKD1_k127_5392095_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1563.0
HKD1_k127_5392095_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.552e-230 726.0
HKD1_k127_5392095_10 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000001937 231.0
HKD1_k127_5392095_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001127 205.0
HKD1_k127_5392095_12 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD1_k127_5392095_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000005517 174.0
HKD1_k127_5392095_14 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000745 168.0
HKD1_k127_5392095_15 membrane K08978,K12962 - - 0.000000000000000000000000000000000000001444 150.0
HKD1_k127_5392095_16 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000001785 112.0
HKD1_k127_5392095_17 lipolytic protein G-D-S-L family K20306 - - 0.00000000000000000000003649 113.0
HKD1_k127_5392095_18 - - - - 0.000000000002571 70.0
HKD1_k127_5392095_19 GDSL-like Lipase/Acylhydrolase - - - 0.00000000002167 76.0
HKD1_k127_5392095_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 6.712e-217 687.0
HKD1_k127_5392095_20 PFAM YcfA-like protein - - - 0.0000000007844 62.0
HKD1_k127_5392095_21 PFAM YcfA-like protein - - - 0.000005307 51.0
HKD1_k127_5392095_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 581.0
HKD1_k127_5392095_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 431.0
HKD1_k127_5392095_5 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 342.0
HKD1_k127_5392095_6 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 314.0
HKD1_k127_5392095_7 RNA polymerase sigma factor K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
HKD1_k127_5392095_8 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 299.0
HKD1_k127_5392095_9 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
HKD1_k127_5415946_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1449.0
HKD1_k127_5415946_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1156.0
HKD1_k127_5415946_10 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000004509 205.0
HKD1_k127_5415946_11 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000001333 196.0
HKD1_k127_5415946_12 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000005179 210.0
HKD1_k127_5415946_13 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD1_k127_5415946_14 Hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000000000000001769 186.0
HKD1_k127_5415946_15 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000009673 167.0
HKD1_k127_5415946_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000006896 131.0
HKD1_k127_5415946_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000006436 130.0
HKD1_k127_5415946_18 nickel cation binding K04651 - - 0.00000000000000000000000001956 113.0
HKD1_k127_5415946_19 FAD dependent oxidoreductase - - - 0.0000000000000000000000001509 107.0
HKD1_k127_5415946_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 624.0
HKD1_k127_5415946_20 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000001576 98.0
HKD1_k127_5415946_21 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001799 85.0
HKD1_k127_5415946_24 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD1_k127_5415946_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 522.0
HKD1_k127_5415946_4 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 453.0
HKD1_k127_5415946_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
HKD1_k127_5415946_6 PFAM NADH ubiquinone K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 404.0
HKD1_k127_5415946_7 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
HKD1_k127_5415946_8 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 389.0
HKD1_k127_5415946_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001399 226.0
HKD1_k127_5416443_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 6.916e-281 876.0
HKD1_k127_5416443_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.644e-194 621.0
HKD1_k127_5416443_10 GlcNAc transferase - - - 0.000000000009191 72.0
HKD1_k127_5416443_11 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD1_k127_5416443_12 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00006773 51.0
HKD1_k127_5416443_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 467.0
HKD1_k127_5416443_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 424.0
HKD1_k127_5416443_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 380.0
HKD1_k127_5416443_5 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000002335 186.0
HKD1_k127_5416443_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000002864 183.0
HKD1_k127_5416443_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000003804 186.0
HKD1_k127_5416443_8 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000004402 124.0
HKD1_k127_5458187_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 379.0
HKD1_k127_5458187_1 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
HKD1_k127_5458187_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001324 252.0
HKD1_k127_5458187_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000002049 192.0
HKD1_k127_5491053_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2170.0
HKD1_k127_5491053_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2073.0
HKD1_k127_5491053_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000321 145.0
HKD1_k127_5491053_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000209 87.0
HKD1_k127_5491053_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005585 83.0
HKD1_k127_5491053_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000004 84.0
HKD1_k127_5491053_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1037.0
HKD1_k127_5491053_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 365.0
HKD1_k127_5491053_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
HKD1_k127_5491053_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
HKD1_k127_5491053_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000012 227.0
HKD1_k127_5491053_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
HKD1_k127_5491053_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000002991 166.0
HKD1_k127_5491053_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000002654 152.0
HKD1_k127_5526958_0 E1-E2 ATPase K01547 - 3.6.3.12 7.72e-307 959.0
HKD1_k127_5526958_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.154e-271 847.0
HKD1_k127_5526958_10 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 460.0
HKD1_k127_5526958_11 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 449.0
HKD1_k127_5526958_12 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 430.0
HKD1_k127_5526958_13 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 409.0
HKD1_k127_5526958_14 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HKD1_k127_5526958_15 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 391.0
HKD1_k127_5526958_16 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 355.0
HKD1_k127_5526958_17 PFAM response regulator receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
HKD1_k127_5526958_18 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
HKD1_k127_5526958_19 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003987 294.0
HKD1_k127_5526958_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 3.567e-263 823.0
HKD1_k127_5526958_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005235 270.0
HKD1_k127_5526958_21 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
HKD1_k127_5526958_22 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000001598 177.0
HKD1_k127_5526958_23 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000008036 175.0
HKD1_k127_5526958_24 - - - - 0.00000000000000000000000000000000000000001518 154.0
HKD1_k127_5526958_25 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000172 152.0
HKD1_k127_5526958_26 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000003271 153.0
HKD1_k127_5526958_27 ribonuclease activity - - - 0.0000000000000000000000000003962 117.0
HKD1_k127_5526958_28 Protein of unknown function DUF116 - - - 0.000000000000001038 87.0
HKD1_k127_5526958_29 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000009902 70.0
HKD1_k127_5526958_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 4.139e-242 762.0
HKD1_k127_5526958_4 PFAM response regulator receiver K11384 - - 7.206e-215 675.0
HKD1_k127_5526958_5 Signal transduction histidine kinase K07636 - 2.7.13.3 2.873e-198 633.0
HKD1_k127_5526958_6 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 9.194e-196 615.0
HKD1_k127_5526958_7 carbon starvation protein CstA K06200 - - 9.091e-194 619.0
HKD1_k127_5526958_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 592.0
HKD1_k127_5526958_9 PBP superfamily domain K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 467.0
HKD1_k127_5650380_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 603.0
HKD1_k127_5650380_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 385.0
HKD1_k127_5650380_10 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000001078 164.0
HKD1_k127_5650380_11 MlaC protein K07323 - - 0.000000000000000000000000000000000000000002603 163.0
HKD1_k127_5650380_12 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000004035 133.0
HKD1_k127_5650380_13 MlaC protein K07323 - - 0.00000000000000000000000000000001227 134.0
HKD1_k127_5650380_14 MlaC protein K07323 - - 0.000000000000000000000000000007641 127.0
HKD1_k127_5650380_15 Right handed beta helix region - - - 0.0000000000000000000000002632 117.0
HKD1_k127_5650380_16 Right handed beta helix region - - - 0.00000000000000000007817 100.0
HKD1_k127_5650380_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
HKD1_k127_5650380_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 359.0
HKD1_k127_5650380_4 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 353.0
HKD1_k127_5650380_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
HKD1_k127_5650380_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 311.0
HKD1_k127_5650380_7 - - - - 0.00000000000000000000000000000000000000000000000000002468 195.0
HKD1_k127_5650380_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000004417 190.0
HKD1_k127_5650380_9 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000009457 194.0
HKD1_k127_5732587_0 Reductase C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 582.0
HKD1_k127_5732587_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
HKD1_k127_5732587_2 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000001383 149.0
HKD1_k127_5732587_3 Protein of unknown function (DUF3124) - - - 0.00000000000000001883 89.0
HKD1_k127_5732587_4 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD1_k127_5732898_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 467.0
HKD1_k127_5732898_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 423.0
HKD1_k127_5732898_2 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 401.0
HKD1_k127_5732898_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
HKD1_k127_5732898_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007013 284.0
HKD1_k127_5732898_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 244.0
HKD1_k127_5732898_6 HD domain - - - 0.000000000000000000000000000000000000000000000006563 182.0
HKD1_k127_5732898_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000005724 130.0
HKD1_k127_5732898_8 Phage integrase family - - - 0.00000000000000004441 83.0
HKD1_k127_5732898_9 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD1_k127_573448_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0 1220.0
HKD1_k127_573448_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.604e-262 833.0
HKD1_k127_573448_10 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003097 282.0
HKD1_k127_573448_11 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
HKD1_k127_573448_12 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000005909 100.0
HKD1_k127_573448_13 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000008215 92.0
HKD1_k127_573448_14 Domain of unknown function (DUF4282) - - - 0.0000000000000001142 83.0
HKD1_k127_573448_2 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 1.542e-217 680.0
HKD1_k127_573448_3 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 3.776e-198 629.0
HKD1_k127_573448_4 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 587.0
HKD1_k127_573448_5 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 564.0
HKD1_k127_573448_6 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 560.0
HKD1_k127_573448_7 Metallo-beta-lactamase superfamily domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 528.0
HKD1_k127_573448_8 PFAM Radical SAM K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
HKD1_k127_573448_9 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 393.0
HKD1_k127_5743845_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.099e-225 712.0
HKD1_k127_5743845_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 414.0
HKD1_k127_5743845_10 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000043 248.0
HKD1_k127_5743845_11 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004051 244.0
HKD1_k127_5743845_12 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000001056 182.0
HKD1_k127_5743845_13 Right handed beta helix region - - - 0.00000000000000000000000001457 118.0
HKD1_k127_5743845_14 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000002017 102.0
HKD1_k127_5743845_16 Pyridoxamine 5'-phosphate oxidase - - - 0.00001841 53.0
HKD1_k127_5743845_17 cell wall organization - - - 0.0001414 51.0
HKD1_k127_5743845_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 387.0
HKD1_k127_5743845_3 PFAM Glycosyl transferase, group 1 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 369.0
HKD1_k127_5743845_4 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 340.0
HKD1_k127_5743845_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 335.0
HKD1_k127_5743845_6 PFAM glycosyl transferase, family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
HKD1_k127_5743845_7 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 296.0
HKD1_k127_5743845_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 292.0
HKD1_k127_5743845_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000098 283.0
HKD1_k127_5808151_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 2.51e-276 863.0
HKD1_k127_5808151_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.399e-230 725.0
HKD1_k127_5808151_10 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 352.0
HKD1_k127_5808151_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 332.0
HKD1_k127_5808151_12 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 333.0
HKD1_k127_5808151_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 286.0
HKD1_k127_5808151_14 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
HKD1_k127_5808151_15 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000001678 200.0
HKD1_k127_5808151_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001108 198.0
HKD1_k127_5808151_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000000000000002771 154.0
HKD1_k127_5808151_19 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000001207 133.0
HKD1_k127_5808151_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.065e-222 698.0
HKD1_k127_5808151_20 PFAM Methylamine - - - 0.0000000000000000000000000000442 123.0
HKD1_k127_5808151_21 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000002266 120.0
HKD1_k127_5808151_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000008011 109.0
HKD1_k127_5808151_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00001151 53.0
HKD1_k127_5808151_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 5.74e-199 624.0
HKD1_k127_5808151_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 520.0
HKD1_k127_5808151_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 504.0
HKD1_k127_5808151_6 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 508.0
HKD1_k127_5808151_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 495.0
HKD1_k127_5808151_8 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 396.0
HKD1_k127_5808151_9 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 390.0
HKD1_k127_5830271_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.27e-261 812.0
HKD1_k127_5830271_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 406.0
HKD1_k127_5830271_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 320.0
HKD1_k127_5830271_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000288 233.0
HKD1_k127_584264_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0 1140.0
HKD1_k127_584264_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 1.088e-297 931.0
HKD1_k127_584264_10 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
HKD1_k127_584264_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 306.0
HKD1_k127_584264_12 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 298.0
HKD1_k127_584264_13 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
HKD1_k127_584264_14 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
HKD1_k127_584264_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001777 257.0
HKD1_k127_584264_16 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007959 263.0
HKD1_k127_584264_17 Phosphorylase superfamily K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000528 226.0
HKD1_k127_584264_18 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000004791 181.0
HKD1_k127_584264_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 9.286e-260 805.0
HKD1_k127_584264_3 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 495.0
HKD1_k127_584264_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 493.0
HKD1_k127_584264_5 transport system involved in gliding motility auxiliary component-like K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 474.0
HKD1_k127_584264_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 468.0
HKD1_k127_584264_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 432.0
HKD1_k127_584264_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 416.0
HKD1_k127_584264_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 399.0
HKD1_k127_5849043_0 cytochrome c biogenesis protein, transmembrane region K04084 - 1.8.1.8 2.251e-197 623.0
HKD1_k127_5849043_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 509.0
HKD1_k127_5849043_10 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000003161 205.0
HKD1_k127_5849043_11 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000002604 196.0
HKD1_k127_5849043_12 AMP binding - - - 0.0000000000000000000000000000000000000000000003268 175.0
HKD1_k127_5849043_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000004677 158.0
HKD1_k127_5849043_14 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000001217 154.0
HKD1_k127_5849043_15 PFAM regulatory protein, ArsR K22043 - - 0.00000000000000000000000000000000001363 138.0
HKD1_k127_5849043_16 - - - - 0.00000000000000000000000000000003394 126.0
HKD1_k127_5849043_18 Plasmid maintenance system killer - - - 0.00000000000000000000000001007 112.0
HKD1_k127_5849043_19 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000002763 113.0
HKD1_k127_5849043_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 482.0
HKD1_k127_5849043_20 - - - - 0.0000000000000000000000003685 106.0
HKD1_k127_5849043_21 Sh3 type 3 domain protein K03642,K07184 - - 0.000000000000000000005043 99.0
HKD1_k127_5849043_22 - - - - 0.00000000000000009465 81.0
HKD1_k127_5849043_24 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000001415 71.0
HKD1_k127_5849043_25 - - - - 0.000004404 50.0
HKD1_k127_5849043_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000007318 59.0
HKD1_k127_5849043_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 467.0
HKD1_k127_5849043_4 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
HKD1_k127_5849043_5 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 388.0
HKD1_k127_5849043_6 transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 349.0
HKD1_k127_5849043_7 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 334.0
HKD1_k127_5849043_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 312.0
HKD1_k127_5849043_9 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
HKD1_k127_5850685_0 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 387.0
HKD1_k127_5850685_1 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 331.0
HKD1_k127_5850685_2 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
HKD1_k127_5850685_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005506 282.0
HKD1_k127_5850685_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003207 258.0
HKD1_k127_5850685_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
HKD1_k127_5850685_6 NTPase - - - 0.0000000000000000000000000000000001005 139.0
HKD1_k127_5850685_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000189 111.0
HKD1_k127_5850685_8 Xylose isomerase-like TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000008016 106.0
HKD1_k127_5850685_9 granule-associated protein - - - 0.000000000000002444 79.0
HKD1_k127_5870362_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.114e-241 748.0
HKD1_k127_5870362_1 Ammonium Transporter K03320 - - 4.49e-211 661.0
HKD1_k127_5870362_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 356.0
HKD1_k127_5870362_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000003229 204.0
HKD1_k127_5870362_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000008014 151.0
HKD1_k127_5870362_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000209 103.0
HKD1_k127_5923594_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 8.586e-296 929.0
HKD1_k127_5923594_1 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 5.668e-278 861.0
HKD1_k127_5923594_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 550.0
HKD1_k127_5923594_11 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 488.0
HKD1_k127_5923594_12 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 418.0
HKD1_k127_5923594_13 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 398.0
HKD1_k127_5923594_14 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 382.0
HKD1_k127_5923594_15 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
HKD1_k127_5923594_16 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 332.0
HKD1_k127_5923594_17 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 304.0
HKD1_k127_5923594_18 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 268.0
HKD1_k127_5923594_19 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
HKD1_k127_5923594_2 4Fe-4S ferredoxin iron-sulfur binding - - - 5.884e-243 766.0
HKD1_k127_5923594_20 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HKD1_k127_5923594_21 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
HKD1_k127_5923594_22 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000002578 141.0
HKD1_k127_5923594_23 Transcriptional regulator - - - 0.00000000000000000000000000000000005762 136.0
HKD1_k127_5923594_24 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000004933 129.0
HKD1_k127_5923594_25 addiction module killer protein - - - 0.000000000000000000000001946 104.0
HKD1_k127_5923594_26 PFAM DsrE family protein - - - 0.000000000000000001362 88.0
HKD1_k127_5923594_27 - - - - 0.000000000000001227 83.0
HKD1_k127_5923594_28 addiction module killer protein - - - 0.000002998 49.0
HKD1_k127_5923594_29 Rhodanese-related sulfurtransferase - - - 0.000006057 49.0
HKD1_k127_5923594_3 L-carnitine dehydratase bile acid-inducible protein F - - - 1.302e-218 685.0
HKD1_k127_5923594_30 Sulfur carrier protein TusA K04085 - - 0.00006198 49.0
HKD1_k127_5923594_4 acyl-CoA transferases carnitine dehydratase - - - 1.349e-213 671.0
HKD1_k127_5923594_5 penicillin binding K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 616.0
HKD1_k127_5923594_6 HMGL-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 582.0
HKD1_k127_5923594_7 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 589.0
HKD1_k127_5923594_8 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 565.0
HKD1_k127_5923594_9 Short chain fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 551.0
HKD1_k127_5937568_0 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 1.877e-200 643.0
HKD1_k127_5937568_1 - - - - 0.00000000005378 67.0
HKD1_k127_5937568_2 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0000139 52.0
HKD1_k127_5965467_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1147.0
HKD1_k127_5965467_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1084.0
HKD1_k127_5965467_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000003834 138.0
HKD1_k127_5965467_11 - - - - 0.0000000000000000000000000001056 125.0
HKD1_k127_5965467_12 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.0000000000000000000000126 106.0
HKD1_k127_5965467_13 protein trimerization - - - 0.000000000000000000000243 107.0
HKD1_k127_5965467_2 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 545.0
HKD1_k127_5965467_3 peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 467.0
HKD1_k127_5965467_4 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 470.0
HKD1_k127_5965467_5 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 462.0
HKD1_k127_5965467_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 302.0
HKD1_k127_5965467_7 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 302.0
HKD1_k127_5965467_8 PFAM Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 256.0
HKD1_k127_5965467_9 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000002697 169.0
HKD1_k127_6020839_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 381.0
HKD1_k127_6020839_1 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 323.0
HKD1_k127_6020839_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000002109 96.0
HKD1_k127_6025952_0 PFAM Radical SAM superfamily - - - 3.361e-280 867.0
HKD1_k127_6025952_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.375e-240 751.0
HKD1_k127_6025952_10 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000134 253.0
HKD1_k127_6025952_11 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000017 229.0
HKD1_k127_6025952_12 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
HKD1_k127_6025952_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
HKD1_k127_6025952_14 anaphase-promoting complex-dependent catabolic process - - - 0.00000000000000000000000000000000000000000000000000002933 192.0
HKD1_k127_6025952_15 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000008702 184.0
HKD1_k127_6025952_16 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000000000000004018 161.0
HKD1_k127_6025952_17 protein kinase activity - - - 0.0000000000000000000000000000000004234 141.0
HKD1_k127_6025952_19 PFAM Integrase catalytic region - - - 0.00000000000000000000000000001376 121.0
HKD1_k127_6025952_21 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000003105 117.0
HKD1_k127_6025952_22 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000008257 110.0
HKD1_k127_6025952_23 NlpC/P60 family K21471 - - 0.00000000000000000000007712 106.0
HKD1_k127_6025952_24 Dodecin K09165 - - 0.0000000000000000000001381 99.0
HKD1_k127_6025952_25 Dodecin K09165 - - 0.0000000000000000000002368 98.0
HKD1_k127_6025952_26 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000001416 92.0
HKD1_k127_6025952_27 Winged helix-turn helix - - - 0.000000000000000003866 85.0
HKD1_k127_6025952_28 COG2801 Transposase and inactivated derivatives - - - 0.0000000005485 61.0
HKD1_k127_6025952_29 ribosomal protein - - - 0.000000001185 64.0
HKD1_k127_6025952_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 362.0
HKD1_k127_6025952_32 - - - - 0.00001748 50.0
HKD1_k127_6025952_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
HKD1_k127_6025952_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 327.0
HKD1_k127_6025952_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 302.0
HKD1_k127_6025952_7 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002089 274.0
HKD1_k127_6025952_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
HKD1_k127_6025952_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001927 279.0
HKD1_k127_6046334_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1152.0
HKD1_k127_6046334_1 SMART Elongator protein 3 MiaB NifB - - - 3.112e-230 720.0
HKD1_k127_6046334_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 291.0
HKD1_k127_6046334_12 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
HKD1_k127_6046334_13 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000003109 241.0
HKD1_k127_6046334_14 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000000000000000000000000001235 188.0
HKD1_k127_6046334_15 Type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000157 194.0
HKD1_k127_6046334_16 type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000007732 188.0
HKD1_k127_6046334_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000004513 161.0
HKD1_k127_6046334_18 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000008411 166.0
HKD1_k127_6046334_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 602.0
HKD1_k127_6046334_20 PFAM Response regulator receiver domain - - - 0.00000000000000000000000003309 124.0
HKD1_k127_6046334_21 monooxygenase activity - - - 0.00000000000000000000003389 106.0
HKD1_k127_6046334_22 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000006992 103.0
HKD1_k127_6046334_23 cell cycle K05589,K12065,K13052 - - 0.000000000000000000003672 100.0
HKD1_k127_6046334_24 protein homooligomerization - - - 0.00000000000000000003444 105.0
HKD1_k127_6046334_25 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000002983 93.0
HKD1_k127_6046334_26 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000004377 74.0
HKD1_k127_6046334_27 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000001693 72.0
HKD1_k127_6046334_28 3D domain protein - - - 0.00000000000687 73.0
HKD1_k127_6046334_29 - - - - 0.0000000003053 61.0
HKD1_k127_6046334_3 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 596.0
HKD1_k127_6046334_30 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000002803 59.0
HKD1_k127_6046334_4 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 477.0
HKD1_k127_6046334_5 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 428.0
HKD1_k127_6046334_6 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
HKD1_k127_6046334_7 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 365.0
HKD1_k127_6046334_8 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
HKD1_k127_6046334_9 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
HKD1_k127_6120497_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 467.0
HKD1_k127_6120497_1 PFAM Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.0000000000000000000000000000000000000000000000004092 181.0
HKD1_k127_6120497_2 - - - - 0.00000000000000000002746 96.0
HKD1_k127_6120497_3 ISXO2-like transposase domain - - - 0.000000001429 59.0
HKD1_k127_6120598_0 CoA binding domain K09181 - - 1.252e-278 872.0
HKD1_k127_6120598_1 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 439.0
HKD1_k127_6120598_10 mRNA binding - - - 0.000000000000193 72.0
HKD1_k127_6120598_11 Addiction module toxin RelE StbE family - - - 0.000000000004794 68.0
HKD1_k127_6120598_12 ISXO2-like transposase domain - - - 0.000000001429 59.0
HKD1_k127_6120598_13 - - - - 0.000000237 53.0
HKD1_k127_6120598_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 338.0
HKD1_k127_6120598_3 TIGRFAM Addiction module toxin, Txe YoeB - - - 0.0000000000000000000000000000000000001724 144.0
HKD1_k127_6120598_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000233 118.0
HKD1_k127_6120598_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000007515 110.0
HKD1_k127_6120598_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000007658 112.0
HKD1_k127_6120598_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001075 93.0
HKD1_k127_6120598_8 mRNA binding - - - 0.000000000000001359 78.0
HKD1_k127_6120598_9 - - - - 0.00000000000006255 74.0
HKD1_k127_6124982_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 611.0
HKD1_k127_6124982_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 513.0
HKD1_k127_6124982_10 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000003242 249.0
HKD1_k127_6124982_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
HKD1_k127_6124982_12 HicB family - - - 0.000000000000000000000000000000000000000000000000003724 183.0
HKD1_k127_6124982_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001783 176.0
HKD1_k127_6124982_14 - - - - 0.0000000000000000000007749 97.0
HKD1_k127_6124982_15 CoA-transferase family III - - - 0.000000000000000000002722 95.0
HKD1_k127_6124982_16 nuclease activity K06218 - - 0.0000000000000000009883 88.0
HKD1_k127_6124982_18 - - - - 0.000000007143 62.0
HKD1_k127_6124982_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 494.0
HKD1_k127_6124982_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 437.0
HKD1_k127_6124982_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 435.0
HKD1_k127_6124982_5 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 409.0
HKD1_k127_6124982_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 381.0
HKD1_k127_6124982_7 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 343.0
HKD1_k127_6124982_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 281.0
HKD1_k127_6124982_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
HKD1_k127_6158904_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1493.0
HKD1_k127_6158904_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789,K18138 - - 0.0 1120.0
HKD1_k127_6158904_2 Biotin-lipoyl like K07799,K18990 - - 0.0000000000000000000009558 96.0
HKD1_k127_6216788_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1191.0
HKD1_k127_6216788_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 1.654e-275 861.0
HKD1_k127_6216788_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 370.0
HKD1_k127_6216788_11 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 346.0
HKD1_k127_6216788_12 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 314.0
HKD1_k127_6216788_13 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
HKD1_k127_6216788_14 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD1_k127_6216788_16 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000001799 161.0
HKD1_k127_6216788_17 PAS fold - - - 0.0000000000000000000000000000000000000001125 162.0
HKD1_k127_6216788_18 cellulose binding - - - 0.000000000000000000000000000000000000000198 171.0
HKD1_k127_6216788_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001289 139.0
HKD1_k127_6216788_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.382e-273 847.0
HKD1_k127_6216788_20 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000002111 117.0
HKD1_k127_6216788_21 - - - - 0.0002596 52.0
HKD1_k127_6216788_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 612.0
HKD1_k127_6216788_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 592.0
HKD1_k127_6216788_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 502.0
HKD1_k127_6216788_6 PFAM Glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 489.0
HKD1_k127_6216788_7 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 471.0
HKD1_k127_6216788_8 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 473.0
HKD1_k127_6216788_9 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 418.0
HKD1_k127_6220101_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 1.515e-197 623.0
HKD1_k127_6220101_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 562.0
HKD1_k127_6220101_3 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 446.0
HKD1_k127_6220101_4 ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 406.0
HKD1_k127_6220101_5 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 334.0
HKD1_k127_6220101_7 - - - - 0.000000000000000000000000000003706 123.0
HKD1_k127_6220101_8 transposition, DNA-mediated - - - 0.0000000000000000004943 88.0
HKD1_k127_6249138_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.077e-318 1005.0
HKD1_k127_6249138_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 4.172e-312 970.0
HKD1_k127_6249138_10 PFAM Major Facilitator Superfamily - - - 0.000001446 53.0
HKD1_k127_6249138_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 1.326e-213 674.0
HKD1_k127_6249138_3 Efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 505.0
HKD1_k127_6249138_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 477.0
HKD1_k127_6249138_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 439.0
HKD1_k127_6249138_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004925 257.0
HKD1_k127_6249138_8 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000001157 228.0
HKD1_k127_6249138_9 Transcriptional regulator, marR - - - 0.00000000000000000000000000000002846 130.0
HKD1_k127_625099_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 7.499e-231 724.0
HKD1_k127_625099_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 6.165e-206 655.0
HKD1_k127_625099_10 Thioesterase - - - 0.0000000000000000000000000000000000000000000000001845 179.0
HKD1_k127_625099_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000005164 173.0
HKD1_k127_625099_12 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000006108 170.0
HKD1_k127_625099_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000003599 89.0
HKD1_k127_625099_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000008864 68.0
HKD1_k127_625099_18 phosphorelay signal transduction system - - - 0.000003005 54.0
HKD1_k127_625099_2 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 2.158e-198 629.0
HKD1_k127_625099_3 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 526.0
HKD1_k127_625099_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 443.0
HKD1_k127_625099_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 308.0
HKD1_k127_625099_7 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
HKD1_k127_625099_8 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000002677 220.0
HKD1_k127_625099_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000008973 198.0
HKD1_k127_6257530_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 604.0
HKD1_k127_6257530_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 476.0
HKD1_k127_6257530_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 413.0
HKD1_k127_6257530_3 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
HKD1_k127_6257530_4 SEC-C Motif Domain Protein - - - 0.0000000000000000000000000000000000000000000000000000006213 201.0
HKD1_k127_6257530_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000004604 177.0
HKD1_k127_6257530_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000002381 158.0
HKD1_k127_6257530_7 permease K07089 - - 0.000000000000000000000000000000009115 130.0
HKD1_k127_6257530_8 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000001755 78.0
HKD1_k127_6267898_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 9.282e-197 623.0
HKD1_k127_6267898_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
HKD1_k127_6267898_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
HKD1_k127_6267898_3 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001789 250.0
HKD1_k127_6267898_4 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.0000000000000000001618 95.0
HKD1_k127_6443438_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0 1134.0
HKD1_k127_6443438_1 PFAM Pyruvate carboxyltransferase - - - 1.378e-317 979.0
HKD1_k127_6443438_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000008155 149.0
HKD1_k127_6443438_11 SpoIIAA-like - - - 0.000000000000000000000000000001186 124.0
HKD1_k127_6443438_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.922e-283 881.0
HKD1_k127_6443438_3 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.118e-283 876.0
HKD1_k127_6443438_4 Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 345.0
HKD1_k127_6443438_5 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
HKD1_k127_6443438_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
HKD1_k127_6443438_7 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000132 217.0
HKD1_k127_6443438_8 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000008242 199.0
HKD1_k127_6443438_9 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000004025 162.0
HKD1_k127_6502886_0 membrane protein involved in D-alanine export K19294 - - 4.141e-210 665.0
HKD1_k127_6502886_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 605.0
HKD1_k127_6502886_10 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000007016 237.0
HKD1_k127_6502886_11 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000002894 204.0
HKD1_k127_6502886_12 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000006824 196.0
HKD1_k127_6502886_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000003647 123.0
HKD1_k127_6502886_15 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000188 106.0
HKD1_k127_6502886_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001462 71.0
HKD1_k127_6502886_18 Transposase is116 is110 is902 family K07486 - - 0.0000001892 52.0
HKD1_k127_6502886_19 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD1_k127_6502886_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 601.0
HKD1_k127_6502886_3 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 534.0
HKD1_k127_6502886_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 497.0
HKD1_k127_6502886_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 479.0
HKD1_k127_6502886_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 453.0
HKD1_k127_6502886_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 388.0
HKD1_k127_6502886_8 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 327.0
HKD1_k127_6502886_9 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
HKD1_k127_6502890_0 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 544.0
HKD1_k127_6502890_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 491.0
HKD1_k127_6502890_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 454.0
HKD1_k127_6502890_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
HKD1_k127_6502890_4 ligase activity K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
HKD1_k127_6502890_5 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002253 223.0
HKD1_k127_6502890_6 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000000000000000000000000000000000001161 217.0
HKD1_k127_6502890_8 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000001355 80.0
HKD1_k127_6502890_9 Transposase is116 is110 is902 family K07486 - - 0.0000001892 52.0
HKD1_k127_6570891_0 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 549.0
HKD1_k127_6570891_1 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 563.0
HKD1_k127_6570891_10 3D domain protein K21471 - - 0.00001351 53.0
HKD1_k127_6570891_2 transporter (mgtE) K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 456.0
HKD1_k127_6570891_3 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 363.0
HKD1_k127_6570891_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 332.0
HKD1_k127_6570891_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000002832 120.0
HKD1_k127_6570891_6 - - - - 0.0000000000000000004516 91.0
HKD1_k127_6570891_7 - - - - 0.00000000000009223 78.0
HKD1_k127_6570891_9 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD1_k127_6627793_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1784.0
HKD1_k127_6627793_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1032.0
HKD1_k127_6627793_11 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
HKD1_k127_6627793_12 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, beta region K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004097 271.0
HKD1_k127_6627793_13 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008579 234.0
HKD1_k127_6627793_14 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000004244 163.0
HKD1_k127_6627793_15 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07216,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000002465 132.0
HKD1_k127_6627793_16 - - - - 0.0000000000000000000000000009785 116.0
HKD1_k127_6627793_17 Alkylmercury lyase - - - 0.00000000000000000000000002958 110.0
HKD1_k127_6627793_19 part of a sulfur-relay system K11179 - - 0.0000000000000000001779 94.0
HKD1_k127_6627793_2 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 7.307e-284 893.0
HKD1_k127_6627793_20 - - - - 0.0000000000000004405 79.0
HKD1_k127_6627793_22 Alkylmercury lyase - - - 0.000000001992 60.0
HKD1_k127_6627793_3 PFAM magnesium chelatase K07391 - - 8.939e-219 691.0
HKD1_k127_6627793_4 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 602.0
HKD1_k127_6627793_5 reductase alpha subunit K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 552.0
HKD1_k127_6627793_6 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 549.0
HKD1_k127_6627793_7 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 426.0
HKD1_k127_6627793_8 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 415.0
HKD1_k127_6627793_9 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 366.0
HKD1_k127_6707036_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 498.0
HKD1_k127_6707036_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 487.0
HKD1_k127_6707036_2 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 426.0
HKD1_k127_6707036_3 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001738 292.0
HKD1_k127_6707036_4 FecR protein - - - 0.00000000000000000000000000000000000000246 164.0
HKD1_k127_6786322_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 6.496e-202 634.0
HKD1_k127_6786322_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 520.0
HKD1_k127_6786322_10 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000005215 162.0
HKD1_k127_6786322_11 Universal stress protein family - - - 0.00000000000000000000000000003375 123.0
HKD1_k127_6786322_12 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000004171 115.0
HKD1_k127_6786322_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 445.0
HKD1_k127_6786322_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 408.0
HKD1_k127_6786322_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
HKD1_k127_6786322_5 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 248.0
HKD1_k127_6786322_6 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000007292 238.0
HKD1_k127_6786322_8 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000001772 204.0
HKD1_k127_6786322_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000018 163.0
HKD1_k127_6795365_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 434.0
HKD1_k127_6795365_1 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
HKD1_k127_6795365_2 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
HKD1_k127_6795365_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000002044 207.0
HKD1_k127_6795365_4 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000871 199.0
HKD1_k127_6795365_5 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000001288 177.0
HKD1_k127_6795365_6 - - - - 0.000000000000000000000000000000000001661 143.0
HKD1_k127_6795365_7 PFAM PQQ enzyme repeat - - - 0.000000000000000000001778 100.0
HKD1_k127_6795365_8 ISXO2-like transposase domain - - - 0.0000000001903 61.0
HKD1_k127_6823143_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.225e-218 695.0
HKD1_k127_6823143_1 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 561.0
HKD1_k127_6823143_10 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000005495 160.0
HKD1_k127_6823143_11 - - - - 0.0000000000000000000000000000007801 121.0
HKD1_k127_6823143_12 - - - - 0.0000000000000000000000001276 112.0
HKD1_k127_6823143_13 - - - - 0.000000000000000000108 94.0
HKD1_k127_6823143_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 402.0
HKD1_k127_6823143_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 383.0
HKD1_k127_6823143_4 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 380.0
HKD1_k127_6823143_5 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 380.0
HKD1_k127_6823143_6 Aspartate ammonia-lyase K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 370.0
HKD1_k127_6823143_7 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
HKD1_k127_6823143_8 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
HKD1_k127_6823143_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000001893 162.0
HKD1_k127_690603_0 ATPase domain of DNA mismatch repair MUTS family K07456 - - 1.404e-222 714.0
HKD1_k127_690603_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 405.0
HKD1_k127_690603_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 325.0
HKD1_k127_690603_3 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000002473 206.0
HKD1_k127_690603_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000001936 145.0
HKD1_k127_690603_5 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001763 109.0
HKD1_k127_690603_7 Anti-sigma-28 factor, FlgM K02398 - - 0.000002617 53.0
HKD1_k127_6949048_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1328.0
HKD1_k127_6949048_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 414.0
HKD1_k127_6949048_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 326.0
HKD1_k127_6949048_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002049 281.0
HKD1_k127_6949048_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000001802 199.0
HKD1_k127_6949048_5 - - - - 0.00000000000000000000000000000000000000000000000003076 188.0
HKD1_k127_6949048_6 YHS domain - - - 0.000000000000001992 79.0
HKD1_k127_6949048_7 Histidine kinase - - - 0.00000000004568 74.0
HKD1_k127_69519_0 cluster binding protein - - - 0.0 1006.0
HKD1_k127_69519_1 PFAM Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 585.0
HKD1_k127_69519_10 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000004072 190.0
HKD1_k127_69519_11 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000001059 194.0
HKD1_k127_69519_12 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000002962 194.0
HKD1_k127_69519_13 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000000000000000574 165.0
HKD1_k127_69519_14 MMPL family K07003 - - 0.0000000000000000000000000000000000002116 147.0
HKD1_k127_69519_15 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000006327 145.0
HKD1_k127_69519_16 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.00000000000000000000000000000000001222 141.0
HKD1_k127_69519_17 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000003077 113.0
HKD1_k127_69519_18 PFAM L-lactate permease K03303 - - 0.000000000000000000127 93.0
HKD1_k127_69519_19 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD1_k127_69519_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 514.0
HKD1_k127_69519_20 transposase activity - - - 0.0000001195 60.0
HKD1_k127_69519_21 Concanavalin A-like lectin/glucanases superfamily - - - 0.000005323 51.0
HKD1_k127_69519_22 competence protein - - - 0.0001151 53.0
HKD1_k127_69519_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 452.0
HKD1_k127_69519_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 413.0
HKD1_k127_69519_5 PFAM L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 340.0
HKD1_k127_69519_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
HKD1_k127_69519_7 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 299.0
HKD1_k127_69519_8 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000214 275.0
HKD1_k127_69519_9 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005269 216.0
HKD1_k127_6970970_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 382.0
HKD1_k127_6970970_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 345.0
HKD1_k127_6998358_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 563.0
HKD1_k127_6998358_1 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 518.0
HKD1_k127_6998358_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000001468 158.0
HKD1_k127_6998358_11 PFAM Aldehyde dehydrogenase family K00128,K00130,K00131,K00151,K10217 - 1.2.1.3,1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85,1.2.1.9 0.000000000000000000000000000009193 133.0
HKD1_k127_6998358_12 Multicopper K06324 - 1.16.3.3 0.000000000000000000000001651 109.0
HKD1_k127_6998358_13 - - - - 0.0000000000000000001943 91.0
HKD1_k127_6998358_14 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000000000004006 80.0
HKD1_k127_6998358_2 response to heat K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 425.0
HKD1_k127_6998358_3 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 409.0
HKD1_k127_6998358_4 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
HKD1_k127_6998358_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
HKD1_k127_6998358_6 Bax inhibitor 1 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
HKD1_k127_6998358_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
HKD1_k127_6998358_8 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000006013 205.0
HKD1_k127_6998358_9 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD1_k127_7062680_0 Glycogen debranching enzyme - - - 0.0 1562.0
HKD1_k127_7062680_1 Large extracellular alpha-helical protein K06894 - - 0.0 1090.0
HKD1_k127_7062680_2 Alpha amylase, catalytic domain - - - 2.641e-269 834.0
HKD1_k127_7062680_3 penicillin binding K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 632.0
HKD1_k127_7062680_4 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 374.0
HKD1_k127_7062680_5 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000006866 220.0
HKD1_k127_7062680_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000008566 222.0
HKD1_k127_7062680_7 Transposase IS116/IS110/IS902 family K07486 - - 0.000000000000000000000000000000000000000000000001012 179.0
HKD1_k127_7062680_8 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000008439 138.0
HKD1_k127_7062680_9 L,D-transpeptidase catalytic domain - - - 0.000001907 53.0
HKD1_k127_7079143_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.482e-310 960.0
HKD1_k127_7079143_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.531e-309 960.0
HKD1_k127_7079143_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 316.0
HKD1_k127_7079143_11 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 284.0
HKD1_k127_7079143_12 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003505 277.0
HKD1_k127_7079143_13 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HKD1_k127_7079143_14 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000002563 220.0
HKD1_k127_7079143_15 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
HKD1_k127_7079143_16 transcriptional regulator - - - 0.0000000000000000000000000000000000000000004121 164.0
HKD1_k127_7079143_17 Formate dehydrogenase alpha subunit K00123,K05299,K22015 - 1.17.1.10,1.17.1.9,1.17.99.7 0.000000000000000000000000000000000008204 141.0
HKD1_k127_7079143_19 Right handed beta helix region - - - 0.000000000000000000000000000002447 132.0
HKD1_k127_7079143_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.749e-284 912.0
HKD1_k127_7079143_20 cell redox homeostasis K03671 - - 0.000000000000000000000000000002953 125.0
HKD1_k127_7079143_22 Right handed beta helix region - - - 0.0000000000000000006872 98.0
HKD1_k127_7079143_23 Right handed beta helix region - - - 0.0000000000000000009753 95.0
HKD1_k127_7079143_25 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000002266 93.0
HKD1_k127_7079143_27 Right handed beta helix region - - - 0.0000000000001821 81.0
HKD1_k127_7079143_28 A translational regulator that binds mRNA to regulate translation initiation and or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome- binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW K03563 - - 0.00000000001806 75.0
HKD1_k127_7079143_3 Histidine kinase K07315 - 3.1.3.3 2.44e-239 760.0
HKD1_k127_7079143_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 3.526e-214 672.0
HKD1_k127_7079143_5 class II (D, K and N) K01893 - 6.1.1.22 8.874e-199 627.0
HKD1_k127_7079143_6 molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 580.0
HKD1_k127_7079143_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 487.0
HKD1_k127_7079143_8 Histidine kinase K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 454.0
HKD1_k127_7079143_9 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 345.0
HKD1_k127_7106429_0 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 306.0
HKD1_k127_7106429_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000002117 122.0
HKD1_k127_7109100_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 2.553e-201 640.0
HKD1_k127_7109100_1 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
HKD1_k127_7109100_2 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000004102 76.0
HKD1_k127_7109631_0 Sensory domain found in PocR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 615.0
HKD1_k127_7134767_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1e-322 1000.0
HKD1_k127_7134767_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 8.33e-210 663.0
HKD1_k127_7134767_2 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 602.0
HKD1_k127_7134767_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 553.0
HKD1_k127_7134767_4 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001998 273.0
HKD1_k127_7134767_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000006239 99.0
HKD1_k127_7183481_0 MacB-like periplasmic core domain K02004 - - 0.0 1052.0
HKD1_k127_7183481_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 451.0
HKD1_k127_7183481_10 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K22491 - - 0.0000000000000000000006546 100.0
HKD1_k127_7183481_11 Protein of unknown function (DUF3568) - - - 0.0000000001227 65.0
HKD1_k127_7183481_12 Putative Flp pilus-assembly TadE/G-like - - - 0.000064 54.0
HKD1_k127_7183481_2 radical SAM domain protein K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 405.0
HKD1_k127_7183481_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 393.0
HKD1_k127_7183481_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 296.0
HKD1_k127_7183481_5 PFAM UBA THIF-type NAD FAD binding - - - 0.00000000000000000000000000000000000000000000000002086 190.0
HKD1_k127_7183481_6 PFAM Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000004758 178.0
HKD1_k127_7183481_7 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000008704 147.0
HKD1_k127_7183481_8 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000000000000000000000000001523 145.0
HKD1_k127_7183481_9 - - - - 0.0000000000000000000000000000000004852 139.0
HKD1_k127_7244524_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 442.0
HKD1_k127_7244524_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 415.0
HKD1_k127_7244524_2 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.000000000000000005583 89.0
HKD1_k127_7244524_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000004367 48.0
HKD1_k127_7330542_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1300.0
HKD1_k127_7330542_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004259 277.0
HKD1_k127_7330542_2 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000002377 218.0
HKD1_k127_7330542_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000001107 138.0
HKD1_k127_7330542_5 PFAM Outer membrane efflux protein - - - 0.0000000008987 62.0
HKD1_k127_7544359_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 6.568e-216 689.0
HKD1_k127_7544359_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 586.0
HKD1_k127_7544359_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 302.0
HKD1_k127_7544359_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001459 223.0
HKD1_k127_7638904_0 4Fe-4S dicluster domain - - - 5.372e-310 955.0
HKD1_k127_7638904_1 PFAM Polysulphide reductase, NrfD K00185 - - 2.986e-197 622.0
HKD1_k127_7638904_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 417.0
HKD1_k127_7638904_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
HKD1_k127_7638904_4 - - - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
HKD1_k127_7638904_5 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000009443 164.0
HKD1_k127_7638904_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00176,K00338 - 1.2.7.3,1.6.5.3 0.000000000000000000000000003787 112.0
HKD1_k127_7638904_7 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD1_k127_7714176_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.796e-216 699.0
HKD1_k127_7714176_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 577.0
HKD1_k127_7714176_10 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000008698 205.0
HKD1_k127_7714176_11 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000000000762 179.0
HKD1_k127_7714176_12 Cupin domain - - - 0.0000000000000000000000000000000000000000000003247 169.0
HKD1_k127_7714176_13 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000004293 166.0
HKD1_k127_7714176_14 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000002319 149.0
HKD1_k127_7714176_15 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000009066 144.0
HKD1_k127_7714176_16 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000033 139.0
HKD1_k127_7714176_17 competence protein - - - 0.00000000000000000000000000000000005401 143.0
HKD1_k127_7714176_18 - - - - 0.0000000000000000000000000000000002677 144.0
HKD1_k127_7714176_19 - - - - 0.00000000000000000000000000000159 130.0
HKD1_k127_7714176_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 573.0
HKD1_k127_7714176_20 Sh3 type 3 domain protein K03642,K07184 - - 0.000000000000000000000001929 113.0
HKD1_k127_7714176_21 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000003621 87.0
HKD1_k127_7714176_22 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.0000000000004524 76.0
HKD1_k127_7714176_23 Bacterial SH3 domain homologues - - - 0.00009838 53.0
HKD1_k127_7714176_3 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 516.0
HKD1_k127_7714176_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 395.0
HKD1_k127_7714176_5 Phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 395.0
HKD1_k127_7714176_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002257 282.0
HKD1_k127_7714176_7 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 276.0
HKD1_k127_7714176_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
HKD1_k127_7714176_9 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002641 228.0
HKD1_k127_7821780_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1179.0
HKD1_k127_7821780_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.206e-276 857.0
HKD1_k127_7821780_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 1.769e-271 859.0
HKD1_k127_7821780_3 - - - - 3.653e-208 653.0
HKD1_k127_7821780_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 509.0
HKD1_k127_7821780_5 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 501.0
HKD1_k127_7821780_6 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000003937 172.0
HKD1_k127_7821780_7 - - - - 0.00000000000000000000001288 106.0
HKD1_k127_7821780_8 transposition - - - 0.000002515 53.0
HKD1_k127_7936281_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1337.0
HKD1_k127_7936281_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.195e-307 953.0
HKD1_k127_7936281_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 466.0
HKD1_k127_7936281_11 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 466.0
HKD1_k127_7936281_12 Cytochrome c5530 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 476.0
HKD1_k127_7936281_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
HKD1_k127_7936281_14 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 419.0
HKD1_k127_7936281_15 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 417.0
HKD1_k127_7936281_16 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 413.0
HKD1_k127_7936281_17 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 406.0
HKD1_k127_7936281_18 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 402.0
HKD1_k127_7936281_19 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 414.0
HKD1_k127_7936281_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.476e-283 890.0
HKD1_k127_7936281_20 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 380.0
HKD1_k127_7936281_21 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 368.0
HKD1_k127_7936281_22 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 364.0
HKD1_k127_7936281_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 357.0
HKD1_k127_7936281_24 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 341.0
HKD1_k127_7936281_25 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 338.0
HKD1_k127_7936281_26 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
HKD1_k127_7936281_27 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 334.0
HKD1_k127_7936281_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 312.0
HKD1_k127_7936281_29 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 308.0
HKD1_k127_7936281_3 aminotransferase, class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 558.0
HKD1_k127_7936281_30 PFAM Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 312.0
HKD1_k127_7936281_31 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
HKD1_k127_7936281_32 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 286.0
HKD1_k127_7936281_33 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 292.0
HKD1_k127_7936281_34 PFAM Aminotransferase, class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 289.0
HKD1_k127_7936281_35 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000168 288.0
HKD1_k127_7936281_36 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HKD1_k127_7936281_37 ResB-like family K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001864 291.0
HKD1_k127_7936281_38 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000983 280.0
HKD1_k127_7936281_39 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 283.0
HKD1_k127_7936281_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 509.0
HKD1_k127_7936281_40 COG4448 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009537 269.0
HKD1_k127_7936281_41 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HKD1_k127_7936281_42 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 258.0
HKD1_k127_7936281_43 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
HKD1_k127_7936281_44 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000003228 234.0
HKD1_k127_7936281_45 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
HKD1_k127_7936281_46 PFAM Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
HKD1_k127_7936281_47 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000004979 229.0
HKD1_k127_7936281_48 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
HKD1_k127_7936281_49 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000004254 234.0
HKD1_k127_7936281_5 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 507.0
HKD1_k127_7936281_50 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000001608 220.0
HKD1_k127_7936281_51 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
HKD1_k127_7936281_52 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
HKD1_k127_7936281_53 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002607 233.0
HKD1_k127_7936281_54 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
HKD1_k127_7936281_55 SAF K02279 - - 0.00000000000000000000000000000000000000000000000000000000009565 213.0
HKD1_k127_7936281_56 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
HKD1_k127_7936281_57 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001894 209.0
HKD1_k127_7936281_58 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000007645 184.0
HKD1_k127_7936281_59 PFAM NUDIX domain - - - 0.0000000000000000000000000000000000000000000001578 174.0
HKD1_k127_7936281_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
HKD1_k127_7936281_60 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000219 171.0
HKD1_k127_7936281_61 - - - - 0.0000000000000000000000000000000000000000000006379 173.0
HKD1_k127_7936281_62 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000003222 168.0
HKD1_k127_7936281_63 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000004513 166.0
HKD1_k127_7936281_64 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000009118 156.0
HKD1_k127_7936281_65 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000003611 158.0
HKD1_k127_7936281_66 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000005346 155.0
HKD1_k127_7936281_67 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000006221 160.0
HKD1_k127_7936281_68 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002879 155.0
HKD1_k127_7936281_69 - - - - 0.000000000000000000000000000000000001384 144.0
HKD1_k127_7936281_7 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 483.0
HKD1_k127_7936281_70 Universal stress protein K06149 - - 0.000000000000000000000000000000000003986 141.0
HKD1_k127_7936281_71 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000001796 147.0
HKD1_k127_7936281_72 PAS domain - - - 0.00000000000000000000000000000000003503 152.0
HKD1_k127_7936281_73 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000006117 137.0
HKD1_k127_7936281_75 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000262 124.0
HKD1_k127_7936281_76 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000008281 125.0
HKD1_k127_7936281_77 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000007769 114.0
HKD1_k127_7936281_78 - - - - 0.00000000000000000000000007008 110.0
HKD1_k127_7936281_79 lyase activity - - - 0.0000000000000000000000007634 107.0
HKD1_k127_7936281_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 490.0
HKD1_k127_7936281_80 RelB antitoxin K07473 - - 0.00000000000000000000002136 103.0
HKD1_k127_7936281_81 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.00000000000000000000002394 105.0
HKD1_k127_7936281_82 - - - - 0.00000000000000000000008835 100.0
HKD1_k127_7936281_83 Histidine kinase - - - 0.000000000000000000003003 97.0
HKD1_k127_7936281_84 - - - - 0.000000000000000000009296 95.0
HKD1_k127_7936281_85 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000000616 94.0
HKD1_k127_7936281_86 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000001217 84.0
HKD1_k127_7936281_87 - - - - 0.00000000000000008707 82.0
HKD1_k127_7936281_88 PFAM Thioredoxin K03671 - - 0.0000000000001436 76.0
HKD1_k127_7936281_89 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000006461 70.0
HKD1_k127_7936281_9 PFAM Anthranilate synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 471.0
HKD1_k127_7936281_90 TadE-like protein - - - 0.0000000007539 64.0
HKD1_k127_7936281_92 Flp/Fap pilin component K02651 - - 0.00000001766 57.0
HKD1_k127_7936281_94 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000003244 56.0
HKD1_k127_7944602_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 6.864e-229 712.0
HKD1_k127_7944602_1 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 431.0
HKD1_k127_7944602_2 Belongs to the amidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 427.0
HKD1_k127_7944602_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005143 280.0
HKD1_k127_7944602_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000002327 214.0
HKD1_k127_7944602_5 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000004968 176.0
HKD1_k127_7944602_6 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000008236 154.0
HKD1_k127_7944602_7 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000002472 115.0
HKD1_k127_7964067_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.905e-301 928.0
HKD1_k127_7964067_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 451.0
HKD1_k127_7964067_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000002461 161.0
HKD1_k127_7964067_11 NUDIX domain - - - 0.000000000000000000000000000000000000000005705 161.0
HKD1_k127_7964067_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000007821 155.0
HKD1_k127_7964067_13 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000003151 115.0
HKD1_k127_7964067_14 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.0000000000000000000000614 104.0
HKD1_k127_7964067_15 Coenzyme A transferase K01039,K01040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.12 0.00000000000001113 78.0
HKD1_k127_7964067_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000006961 72.0
HKD1_k127_7964067_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 426.0
HKD1_k127_7964067_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 366.0
HKD1_k127_7964067_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
HKD1_k127_7964067_5 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
HKD1_k127_7964067_6 GTP binding K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 294.0
HKD1_k127_7964067_7 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 288.0
HKD1_k127_7964067_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006504 273.0
HKD1_k127_7964067_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000076 243.0
HKD1_k127_81136_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 485.0
HKD1_k127_81136_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
HKD1_k127_81136_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000008016 139.0
HKD1_k127_81136_11 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000443 138.0
HKD1_k127_81136_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005279 149.0
HKD1_k127_81136_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000001251 128.0
HKD1_k127_81136_14 beta-lactamase domain protein - - - 0.0000000000000000000002024 109.0
HKD1_k127_81136_15 Putative amidoligase enzyme - - - 0.00000000000001757 85.0
HKD1_k127_81136_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000008664 69.0
HKD1_k127_81136_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
HKD1_k127_81136_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
HKD1_k127_81136_4 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 327.0
HKD1_k127_81136_5 PFAM NLP P60 protein K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
HKD1_k127_81136_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004227 221.0
HKD1_k127_81136_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000001303 216.0
HKD1_k127_81136_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006521 200.0
HKD1_k127_81136_9 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000214 171.0
HKD1_k127_871101_0 Fe-S center protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 597.0
HKD1_k127_871101_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 583.0
HKD1_k127_871101_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
HKD1_k127_871101_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 327.0
HKD1_k127_871101_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
HKD1_k127_871101_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000002746 194.0
HKD1_k127_871101_6 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000006253 178.0
HKD1_k127_871101_7 Ferritin-like domain - - - 0.0000000000000000001184 95.0
HKD1_k127_871101_9 - - - - 0.000001063 55.0
HKD1_k127_941376_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 436.0
HKD1_k127_941376_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
HKD1_k127_97650_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 520.0
HKD1_k127_97650_1 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 359.0
HKD1_k127_97650_10 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000004732 170.0
HKD1_k127_97650_11 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000001315 145.0
HKD1_k127_97650_13 TadE-like protein - - - 0.0001415 48.0
HKD1_k127_97650_2 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 344.0
HKD1_k127_97650_3 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 321.0
HKD1_k127_97650_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001341 277.0
HKD1_k127_97650_5 - - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
HKD1_k127_97650_6 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
HKD1_k127_97650_7 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000005568 213.0
HKD1_k127_97650_8 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000002412 195.0
HKD1_k127_97650_9 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000002323 184.0