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Overview

ID MAG01735
Name HKD1_bin.52
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family UBA2999
Genus JBGPJH01
Species
Assembly information
Completeness (%) 96.62
Contamination (%) 1.67
GC content (%) 64.0
N50 (bp) 73,410
Genome size (bp) 4,189,567

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3482

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1011760_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001012 279.0
HKD1_k127_1011760_1 - - - - 0.0000000000000000004008 93.0
HKD1_k127_1019694_0 AcrB/AcrD/AcrF family - - - 3.027e-293 932.0
HKD1_k127_1019694_1 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 531.0
HKD1_k127_1019694_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000001319 223.0
HKD1_k127_1019694_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000005552 220.0
HKD1_k127_1019694_4 - - - - 0.0000000000000000000000000000000000000000000000001057 187.0
HKD1_k127_1019694_5 - - - - 0.000000000000000000000000000001529 134.0
HKD1_k127_1053869_0 Domain of unknown function (DUF1851) - - - 0.0000000000000000000000000002865 121.0
HKD1_k127_1053869_1 COG3209 Rhs family protein K11021 - - 0.0000000000004203 81.0
HKD1_k127_1053869_2 helix_turn_helix, Lux Regulon - - - 0.0000299 48.0
HKD1_k127_1062348_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 419.0
HKD1_k127_1062348_1 alpha/beta hydrolase fold - - - 0.000006552 54.0
HKD1_k127_1080301_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1496.0
HKD1_k127_1080301_1 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 439.0
HKD1_k127_1080301_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 379.0
HKD1_k127_1080301_3 Histidine kinase K02491,K02668,K07697,K07698,K07710,K13532,K13533,K13924 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009653,GO:0009987,GO:0030154,GO:0030435,GO:0032502,GO:0042802,GO:0043934,GO:0043937,GO:0043938,GO:0048518,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0051094,GO:0065007 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 368.0
HKD1_k127_1080301_4 response regulator K02485,K03413,K07684 - - 0.000000000000000000000000000000000000000000000000000006151 196.0
HKD1_k127_1080301_5 KDPG and KHG aldolase K01625,K01631 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008674,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.14,4.1.2.21,4.1.3.42 0.000000000000000000000000000000000000000000003058 179.0
HKD1_k127_1080301_6 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000001907 146.0
HKD1_k127_1080301_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000002786 138.0
HKD1_k127_1080301_8 - - - - 0.0000000000006072 79.0
HKD1_k127_1198489_0 o-methyltransferase - - - 0.000000000000000000000000000000000000000000000000004147 201.0
HKD1_k127_1198489_1 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000239 134.0
HKD1_k127_1198489_2 PFAM Peptidase family M28 - - - 0.0000000000005832 68.0
HKD1_k127_1198489_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000003583 51.0
HKD1_k127_1198489_4 PEP-utilising enzyme, TIM barrel domain K01006 - 2.7.9.1 0.00008835 48.0
HKD1_k127_1261679_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1155.0
HKD1_k127_1261679_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 434.0
HKD1_k127_1261679_10 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000001671 166.0
HKD1_k127_1261679_11 Preprotein translocase, YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000797 90.0
HKD1_k127_1261679_12 peptidyl-tyrosine sulfation - - - 0.0000000000001305 82.0
HKD1_k127_1261679_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 432.0
HKD1_k127_1261679_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 340.0
HKD1_k127_1261679_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
HKD1_k127_1261679_5 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000002055 269.0
HKD1_k127_1261679_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000001016 234.0
HKD1_k127_1261679_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000003261 217.0
HKD1_k127_1261679_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001796 223.0
HKD1_k127_1261679_9 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000653 196.0
HKD1_k127_1303213_0 Pfam:UPF0118 - - - 0.000000000000000000007879 106.0
HKD1_k127_1303213_1 Short repeat of unknown function (DUF308) - - - 0.00000000000001571 80.0
HKD1_k127_1303213_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.0000000000001412 73.0
HKD1_k127_1303213_3 cyclic nucleotide binding K10914 - - 0.000000000001686 76.0
HKD1_k127_1303213_4 Crp Fnr family transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0005292 53.0
HKD1_k127_1329726_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1014.0
HKD1_k127_1329726_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 470.0
HKD1_k127_1329726_10 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000001049 159.0
HKD1_k127_1329726_11 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000006736 157.0
HKD1_k127_1329726_12 membrane K08972 - - 0.000000000000000000000000002174 117.0
HKD1_k127_1329726_13 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000001262 111.0
HKD1_k127_1329726_14 - - - - 0.0000000000000005152 85.0
HKD1_k127_1329726_16 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 0.00001112 54.0
HKD1_k127_1329726_2 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 398.0
HKD1_k127_1329726_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
HKD1_k127_1329726_4 COG4993 Glucose dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 375.0
HKD1_k127_1329726_5 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 318.0
HKD1_k127_1329726_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004006 261.0
HKD1_k127_1329726_7 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000004709 213.0
HKD1_k127_1329726_8 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000003058 192.0
HKD1_k127_1329726_9 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000596 175.0
HKD1_k127_134833_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1514.0
HKD1_k127_134833_1 DNA topological change K03168 - 5.99.1.2 1.351e-253 805.0
HKD1_k127_134833_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 567.0
HKD1_k127_134833_11 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 505.0
HKD1_k127_134833_12 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 484.0
HKD1_k127_134833_13 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 477.0
HKD1_k127_134833_14 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 474.0
HKD1_k127_134833_15 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 480.0
HKD1_k127_134833_16 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 470.0
HKD1_k127_134833_17 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 458.0
HKD1_k127_134833_18 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 445.0
HKD1_k127_134833_19 Aminotransferase class-III K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 436.0
HKD1_k127_134833_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.211e-236 754.0
HKD1_k127_134833_20 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 427.0
HKD1_k127_134833_21 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 426.0
HKD1_k127_134833_22 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HKD1_k127_134833_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 412.0
HKD1_k127_134833_24 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 404.0
HKD1_k127_134833_25 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 402.0
HKD1_k127_134833_26 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 389.0
HKD1_k127_134833_27 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 387.0
HKD1_k127_134833_28 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 394.0
HKD1_k127_134833_29 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 385.0
HKD1_k127_134833_3 DNA topological change K03168 - 5.99.1.2 1.335e-231 742.0
HKD1_k127_134833_30 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 373.0
HKD1_k127_134833_31 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 368.0
HKD1_k127_134833_32 COG4993 Glucose dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 372.0
HKD1_k127_134833_33 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 349.0
HKD1_k127_134833_34 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 347.0
HKD1_k127_134833_35 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 347.0
HKD1_k127_134833_36 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 353.0
HKD1_k127_134833_37 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 325.0
HKD1_k127_134833_38 ATP-dependent Clp protease proteolytic subunit K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 302.0
HKD1_k127_134833_39 PFAM Enoyl-CoA hydratase isomerase family K01715,K13767 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 305.0
HKD1_k127_134833_4 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.232e-227 721.0
HKD1_k127_134833_40 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 307.0
HKD1_k127_134833_41 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 309.0
HKD1_k127_134833_42 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
HKD1_k127_134833_43 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000552 289.0
HKD1_k127_134833_44 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003842 299.0
HKD1_k127_134833_45 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002456 285.0
HKD1_k127_134833_46 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008383 256.0
HKD1_k127_134833_47 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000001471 258.0
HKD1_k127_134833_48 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
HKD1_k127_134833_49 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000001156 243.0
HKD1_k127_134833_5 DNA topological change K03168 - 5.99.1.2 3.083e-222 717.0
HKD1_k127_134833_50 Thermolysin metallopeptidase, alpha-helical domain K01400 GO:0005575,GO:0005576 3.4.24.28 0.000000000000000000000000000000000000000000000000000000000000000000001401 256.0
HKD1_k127_134833_51 GrpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004236 242.0
HKD1_k127_134833_52 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
HKD1_k127_134833_53 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000002872 237.0
HKD1_k127_134833_54 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
HKD1_k127_134833_55 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
HKD1_k127_134833_56 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000003653 242.0
HKD1_k127_134833_57 - - - - 0.000000000000000000000000000000000000000000000000000000000000781 223.0
HKD1_k127_134833_58 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000006503 220.0
HKD1_k127_134833_59 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000001721 216.0
HKD1_k127_134833_6 FAD linked oxidase domain protein - - - 2.217e-218 694.0
HKD1_k127_134833_60 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000002402 205.0
HKD1_k127_134833_61 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000001366 199.0
HKD1_k127_134833_62 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000208 195.0
HKD1_k127_134833_63 Glyoxalase-like domain K08234 - - 0.00000000000000000000000000000000000000000000000006077 186.0
HKD1_k127_134833_64 - - - - 0.000000000000000000000000000000000000000000000001932 185.0
HKD1_k127_134833_65 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000009317 174.0
HKD1_k127_134833_66 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000001305 181.0
HKD1_k127_134833_67 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000001795 188.0
HKD1_k127_134833_68 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000004387 185.0
HKD1_k127_134833_69 - - - - 0.00000000000000000000000000000000000000000003499 176.0
HKD1_k127_134833_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.432e-211 662.0
HKD1_k127_134833_70 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000003917 171.0
HKD1_k127_134833_71 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000003371 162.0
HKD1_k127_134833_72 stage II sporulation - - - 0.000000000000000000000000000000000000008101 159.0
HKD1_k127_134833_73 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000005154 157.0
HKD1_k127_134833_74 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000006102 160.0
HKD1_k127_134833_75 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000001559 156.0
HKD1_k127_134833_76 integral membrane protein - - - 0.0000000000000000000000000000000001092 151.0
HKD1_k127_134833_77 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000004495 142.0
HKD1_k127_134833_78 - - - - 0.00000000000000000000000000000001195 132.0
HKD1_k127_134833_79 - - - - 0.0000000000000000000000000000001811 138.0
HKD1_k127_134833_8 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 4.608e-198 635.0
HKD1_k127_134833_80 membrane K15977 - - 0.0000000000000000000000000000002953 130.0
HKD1_k127_134833_81 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000002966 131.0
HKD1_k127_134833_82 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.00000000000000000000001407 106.0
HKD1_k127_134833_83 phosphoesterases, related to the Icc protein - - - 0.0000000000000000000001547 108.0
HKD1_k127_134833_84 Phosphoglycerate mutase family - - - 0.0000000000000000000003295 102.0
HKD1_k127_134833_85 - - - - 0.000000000000000000001009 100.0
HKD1_k127_134833_86 Methyltransferase domain - - - 0.00000000000000000002272 101.0
HKD1_k127_134833_87 COG4257 Streptogramin lyase K18235 - - 0.00000000000000001605 97.0
HKD1_k127_134833_88 - - - - 0.0000000000000002345 83.0
HKD1_k127_134833_89 Domain of unknown function (DUF4115) - - - 0.00000000001378 74.0
HKD1_k127_134833_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 578.0
HKD1_k127_134833_90 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000001669 55.0
HKD1_k127_134833_91 CHAD domain K01768 - 4.6.1.1 0.0000003275 61.0
HKD1_k127_134833_92 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00002301 53.0
HKD1_k127_134833_93 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001829 54.0
HKD1_k127_134833_94 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.0003512 47.0
HKD1_k127_134833_95 - - - - 0.0005693 43.0
HKD1_k127_1371870_0 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 459.0
HKD1_k127_1371870_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001124 243.0
HKD1_k127_1371870_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004748 243.0
HKD1_k127_1371870_3 - - - - 0.00000000000000000000000000000000000000000000000000002572 201.0
HKD1_k127_1371870_4 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0000000000000000000000000000000000000000001758 174.0
HKD1_k127_1473593_0 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 490.0
HKD1_k127_1473593_1 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.00000000000000008817 81.0
HKD1_k127_1494578_0 DNA topological change - - - 4.063e-228 731.0
HKD1_k127_1494578_1 Dehydrogenase - - - 1.302e-223 711.0
HKD1_k127_1494578_10 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 309.0
HKD1_k127_1494578_11 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 305.0
HKD1_k127_1494578_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000003506 265.0
HKD1_k127_1494578_13 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000001856 191.0
HKD1_k127_1494578_14 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000001488 166.0
HKD1_k127_1494578_15 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000001539 123.0
HKD1_k127_1494578_16 - - - - 0.00000000000000000000002805 110.0
HKD1_k127_1494578_17 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000001094 87.0
HKD1_k127_1494578_2 Dehydrogenase K00117 - 1.1.5.2 5.08e-199 640.0
HKD1_k127_1494578_3 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 471.0
HKD1_k127_1494578_4 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 467.0
HKD1_k127_1494578_5 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 464.0
HKD1_k127_1494578_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 413.0
HKD1_k127_1494578_7 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 407.0
HKD1_k127_1494578_8 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 372.0
HKD1_k127_1494578_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 317.0
HKD1_k127_1638569_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 323.0
HKD1_k127_1638569_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000003734 158.0
HKD1_k127_1638569_2 Nucleotidyltransferase domain - - - 0.00000000000000000000002326 103.0
HKD1_k127_1638569_3 HEPN domain - - - 0.0000179 51.0
HKD1_k127_1669836_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2194.0
HKD1_k127_1669836_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 1.475e-310 963.0
HKD1_k127_1669836_10 phosphorelay sensor kinase activity K02478,K07704 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000006368 222.0
HKD1_k127_1669836_11 - - - - 0.000000000000000000000000000000000000000000000000001626 196.0
HKD1_k127_1669836_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000003045 188.0
HKD1_k127_1669836_13 - - - - 0.00000000000000000000000000000000000000000000000007799 199.0
HKD1_k127_1669836_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000009131 170.0
HKD1_k127_1669836_15 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000008467 172.0
HKD1_k127_1669836_16 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000007068 171.0
HKD1_k127_1669836_17 - - - - 0.00000000000000000000000000000000000003918 157.0
HKD1_k127_1669836_18 Transcriptional regulator K07978,K07979 - - 0.0000000000000000000000000000000006199 135.0
HKD1_k127_1669836_19 Phosphotriesterase family - - - 0.0000000000000000000000000000006158 136.0
HKD1_k127_1669836_2 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 6.348e-243 757.0
HKD1_k127_1669836_20 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000002301 133.0
HKD1_k127_1669836_21 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000006549 125.0
HKD1_k127_1669836_22 Protein of unknown function (DUF504) - - - 0.000000000000000000009633 98.0
HKD1_k127_1669836_23 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000002579 91.0
HKD1_k127_1669836_24 PIN domain - - - 0.0000000000003662 82.0
HKD1_k127_1669836_25 - K01992 - - 0.00000000002047 74.0
HKD1_k127_1669836_26 positive regulation of growth - - - 0.000000001476 61.0
HKD1_k127_1669836_27 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00005682 53.0
HKD1_k127_1669836_29 PIN domain - - - 0.0003061 43.0
HKD1_k127_1669836_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 383.0
HKD1_k127_1669836_4 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 339.0
HKD1_k127_1669836_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008312 278.0
HKD1_k127_1669836_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
HKD1_k127_1669836_7 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
HKD1_k127_1669836_8 HpcH/HpaI aldolase/citrate lyase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000009093 250.0
HKD1_k127_1669836_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000006647 243.0
HKD1_k127_168137_0 DNA topological change K03168 - 5.99.1.2 1.086e-253 806.0
HKD1_k127_168137_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 473.0
HKD1_k127_168137_10 PFAM Cold-shock K03704 - - 0.0000000000008281 70.0
HKD1_k127_168137_11 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000002101 63.0
HKD1_k127_168137_12 DDE domain K07497 - - 0.000003578 49.0
HKD1_k127_168137_13 Integrase core domain K07497 - - 0.00001476 48.0
HKD1_k127_168137_14 transposition K07497 - - 0.0001442 49.0
HKD1_k127_168137_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 468.0
HKD1_k127_168137_3 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 360.0
HKD1_k127_168137_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 350.0
HKD1_k127_168137_5 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 279.0
HKD1_k127_168137_6 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005377 266.0
HKD1_k127_168137_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000135 179.0
HKD1_k127_168137_8 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000004651 128.0
HKD1_k127_168137_9 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000003926 100.0
HKD1_k127_1697400_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1144.0
HKD1_k127_1697400_1 UvrD/REP helicase N-terminal domain - - - 2.455e-288 925.0
HKD1_k127_1697400_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 560.0
HKD1_k127_1697400_11 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 539.0
HKD1_k127_1697400_12 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 544.0
HKD1_k127_1697400_13 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 516.0
HKD1_k127_1697400_14 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 487.0
HKD1_k127_1697400_15 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 472.0
HKD1_k127_1697400_16 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 461.0
HKD1_k127_1697400_17 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 451.0
HKD1_k127_1697400_18 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 442.0
HKD1_k127_1697400_19 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 427.0
HKD1_k127_1697400_2 Heat shock 70 kDa protein K04043 - - 4.674e-285 888.0
HKD1_k127_1697400_20 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 429.0
HKD1_k127_1697400_21 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 413.0
HKD1_k127_1697400_22 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
HKD1_k127_1697400_23 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 383.0
HKD1_k127_1697400_24 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 385.0
HKD1_k127_1697400_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 376.0
HKD1_k127_1697400_26 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 357.0
HKD1_k127_1697400_27 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 355.0
HKD1_k127_1697400_28 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 346.0
HKD1_k127_1697400_29 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
HKD1_k127_1697400_3 GTP-binding protein TypA K06207 - - 2.156e-268 842.0
HKD1_k127_1697400_30 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
HKD1_k127_1697400_31 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
HKD1_k127_1697400_32 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 301.0
HKD1_k127_1697400_33 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 305.0
HKD1_k127_1697400_34 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005161 288.0
HKD1_k127_1697400_35 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
HKD1_k127_1697400_36 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 269.0
HKD1_k127_1697400_37 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000006008 280.0
HKD1_k127_1697400_38 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000001933 263.0
HKD1_k127_1697400_39 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000007326 256.0
HKD1_k127_1697400_4 PD-(D/E)XK nuclease superfamily - - - 4.778e-250 809.0
HKD1_k127_1697400_40 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HKD1_k127_1697400_41 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003924 255.0
HKD1_k127_1697400_42 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000008415 262.0
HKD1_k127_1697400_43 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000001256 253.0
HKD1_k127_1697400_44 Hexosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001722 261.0
HKD1_k127_1697400_45 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000111 251.0
HKD1_k127_1697400_46 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003292 239.0
HKD1_k127_1697400_47 S-adenosylhomocysteine deaminase activity K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000007177 241.0
HKD1_k127_1697400_48 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000005908 239.0
HKD1_k127_1697400_49 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001893 235.0
HKD1_k127_1697400_5 protein secretion by the type I secretion system K11085 - - 1.252e-249 785.0
HKD1_k127_1697400_50 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
HKD1_k127_1697400_51 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001408 210.0
HKD1_k127_1697400_52 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000000002982 204.0
HKD1_k127_1697400_53 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000003654 204.0
HKD1_k127_1697400_54 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000003024 207.0
HKD1_k127_1697400_55 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000007325 201.0
HKD1_k127_1697400_56 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000000259 208.0
HKD1_k127_1697400_57 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000005251 198.0
HKD1_k127_1697400_58 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002716 193.0
HKD1_k127_1697400_59 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000009385 192.0
HKD1_k127_1697400_6 Oligopeptidase F K08602 - - 1.535e-214 683.0
HKD1_k127_1697400_60 WYL domain K13572 - - 0.00000000000000000000000000000000000000000007899 172.0
HKD1_k127_1697400_61 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000002183 165.0
HKD1_k127_1697400_62 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000004893 161.0
HKD1_k127_1697400_63 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000006275 156.0
HKD1_k127_1697400_64 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000001854 145.0
HKD1_k127_1697400_65 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000002163 152.0
HKD1_k127_1697400_67 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000001334 136.0
HKD1_k127_1697400_68 membrane-bound metal-dependent hydrolase K07038 - - 0.0000000000000000000000000000000288 141.0
HKD1_k127_1697400_69 S1 P1 Nuclease - - - 0.00000000000000000000000000000005718 136.0
HKD1_k127_1697400_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.959e-211 676.0
HKD1_k127_1697400_70 Protein of unknown function DUF45 - - - 0.0000000000000000000000000000001236 133.0
HKD1_k127_1697400_71 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.00000000000000000000000001015 120.0
HKD1_k127_1697400_72 nucleotidyltransferase activity - - - 0.00000000000000000000004853 111.0
HKD1_k127_1697400_73 - - - - 0.0000000000000000000005702 99.0
HKD1_k127_1697400_74 Peptidase M23 - - - 0.0000000000000000000007625 109.0
HKD1_k127_1697400_75 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000001104 91.0
HKD1_k127_1697400_76 Regulatory protein, FmdB family - - - 0.000000000000000001724 93.0
HKD1_k127_1697400_77 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000278 81.0
HKD1_k127_1697400_78 - - - - 0.000000000000004019 79.0
HKD1_k127_1697400_79 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000008197 82.0
HKD1_k127_1697400_8 Insulinase (Peptidase family M16) K07263 - - 2.224e-204 668.0
HKD1_k127_1697400_80 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000002995 76.0
HKD1_k127_1697400_81 Stress responsive A/B Barrel Domain - - - 0.0000000000001964 74.0
HKD1_k127_1697400_82 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000009076 70.0
HKD1_k127_1697400_83 ECF sigma factor - - - 0.0000000001452 67.0
HKD1_k127_1697400_84 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.00000001942 56.0
HKD1_k127_1697400_85 PFAM PEGA domain - - - 0.00000004998 64.0
HKD1_k127_1697400_86 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.000002198 61.0
HKD1_k127_1697400_87 Polysaccharide biosynthesis protein - - - 0.00001609 57.0
HKD1_k127_1697400_88 - - - - 0.00002482 55.0
HKD1_k127_1697400_89 - - - - 0.0000259 53.0
HKD1_k127_1697400_9 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 614.0
HKD1_k127_1776717_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 596.0
HKD1_k127_1776717_1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 299.0
HKD1_k127_1776717_2 ATPase associated with various cellular activities AAA_5 - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 271.0
HKD1_k127_1776717_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000006084 161.0
HKD1_k127_1776717_4 ASCH - - - 0.0000000000000000009852 92.0
HKD1_k127_1776717_5 Autotransporter beta-domain - - - 0.00000007356 64.0
HKD1_k127_1776717_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000001063 55.0
HKD1_k127_1785189_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1467.0
HKD1_k127_1785189_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1348.0
HKD1_k127_1785189_10 Peptidase family M13 K07386 - - 3.221e-213 685.0
HKD1_k127_1785189_100 - - - - 0.00000002126 63.0
HKD1_k127_1785189_101 Surface antigen - - - 0.00000006845 58.0
HKD1_k127_1785189_103 - - - - 0.000001487 57.0
HKD1_k127_1785189_104 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.000003198 55.0
HKD1_k127_1785189_105 - - - - 0.000008831 58.0
HKD1_k127_1785189_106 glucose sorbosone K21430 - - 0.00001203 49.0
HKD1_k127_1785189_107 Psort location Cytoplasmic, score 8.96 - - - 0.0000323 54.0
HKD1_k127_1785189_108 - - - - 0.00004089 53.0
HKD1_k127_1785189_109 Cupin 2, conserved barrel domain protein - - - 0.0001629 52.0
HKD1_k127_1785189_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.098e-212 684.0
HKD1_k127_1785189_110 - - - - 0.0002104 51.0
HKD1_k127_1785189_12 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 7.285e-205 644.0
HKD1_k127_1785189_13 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 1.202e-201 646.0
HKD1_k127_1785189_14 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 7.822e-200 643.0
HKD1_k127_1785189_15 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 569.0
HKD1_k127_1785189_16 nitrite transmembrane transporter activity K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 558.0
HKD1_k127_1785189_17 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 531.0
HKD1_k127_1785189_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 541.0
HKD1_k127_1785189_19 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 499.0
HKD1_k127_1785189_2 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1182.0
HKD1_k127_1785189_20 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 480.0
HKD1_k127_1785189_21 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 475.0
HKD1_k127_1785189_22 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 478.0
HKD1_k127_1785189_23 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 446.0
HKD1_k127_1785189_24 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 447.0
HKD1_k127_1785189_25 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 443.0
HKD1_k127_1785189_26 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 413.0
HKD1_k127_1785189_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 387.0
HKD1_k127_1785189_28 G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 373.0
HKD1_k127_1785189_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 365.0
HKD1_k127_1785189_3 DEAD DEAH box helicase - - - 0.0 1157.0
HKD1_k127_1785189_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 365.0
HKD1_k127_1785189_31 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 370.0
HKD1_k127_1785189_32 Major facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 349.0
HKD1_k127_1785189_33 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 323.0
HKD1_k127_1785189_34 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 315.0
HKD1_k127_1785189_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 321.0
HKD1_k127_1785189_36 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 302.0
HKD1_k127_1785189_37 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 311.0
HKD1_k127_1785189_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 298.0
HKD1_k127_1785189_39 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 290.0
HKD1_k127_1785189_4 Dehydrogenase K00117 - 1.1.5.2 3.894e-299 932.0
HKD1_k127_1785189_40 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 308.0
HKD1_k127_1785189_41 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 299.0
HKD1_k127_1785189_42 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002089 279.0
HKD1_k127_1785189_43 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001111 271.0
HKD1_k127_1785189_44 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003098 287.0
HKD1_k127_1785189_45 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000161 289.0
HKD1_k127_1785189_46 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000005009 269.0
HKD1_k127_1785189_47 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009716 259.0
HKD1_k127_1785189_48 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001889 252.0
HKD1_k127_1785189_49 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000004893 244.0
HKD1_k127_1785189_5 peptidase - - - 5.759e-256 804.0
HKD1_k127_1785189_50 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
HKD1_k127_1785189_51 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001444 246.0
HKD1_k127_1785189_52 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 233.0
HKD1_k127_1785189_53 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
HKD1_k127_1785189_54 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.000000000000000000000000000000000000000000000000000000000000005785 222.0
HKD1_k127_1785189_55 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000006533 237.0
HKD1_k127_1785189_56 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000007108 232.0
HKD1_k127_1785189_57 - - - - 0.00000000000000000000000000000000000000000000000000000000000001231 228.0
HKD1_k127_1785189_58 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000105 225.0
HKD1_k127_1785189_59 - - - - 0.0000000000000000000000000000000000000000000000000000000000002674 224.0
HKD1_k127_1785189_6 O-acetylhomoserine K01740 - 2.5.1.49 4.171e-247 767.0
HKD1_k127_1785189_60 - - - - 0.00000000000000000000000000000000000000000000000000000000006902 219.0
HKD1_k127_1785189_61 - - - - 0.0000000000000000000000000000000000000000000000000000000003951 215.0
HKD1_k127_1785189_62 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000008081 214.0
HKD1_k127_1785189_63 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000275 203.0
HKD1_k127_1785189_64 - - - - 0.00000000000000000000000000000000000000000000000000001674 202.0
HKD1_k127_1785189_65 - - - - 0.000000000000000000000000000000000000000000000000007349 193.0
HKD1_k127_1785189_66 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.0000000000000000000000000000000000000000000000001284 193.0
HKD1_k127_1785189_67 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000002404 184.0
HKD1_k127_1785189_68 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000009344 178.0
HKD1_k127_1785189_69 - - - - 0.000000000000000000000000000000000000000000000003411 190.0
HKD1_k127_1785189_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 2.549e-239 757.0
HKD1_k127_1785189_70 DinB family - - - 0.000000000000000000000000000000000000000000001148 172.0
HKD1_k127_1785189_71 protein kinase related protein - - - 0.00000000000000000000000000000000000000001426 169.0
HKD1_k127_1785189_72 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000002878 157.0
HKD1_k127_1785189_73 DinB family - - - 0.00000000000000000000000000000000000000003873 157.0
HKD1_k127_1785189_74 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000001472 166.0
HKD1_k127_1785189_75 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000002593 158.0
HKD1_k127_1785189_77 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000004305 139.0
HKD1_k127_1785189_79 - - - - 0.000000000000000000000000000000004404 144.0
HKD1_k127_1785189_8 COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase K01081,K11751 - 3.1.3.5,3.6.1.45 6.985e-232 731.0
HKD1_k127_1785189_80 - - - - 0.000000000000000000000000000002323 132.0
HKD1_k127_1785189_81 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000001025 124.0
HKD1_k127_1785189_82 chromosome segregation K03497 - - 0.000000000000000000000001781 109.0
HKD1_k127_1785189_83 - - - - 0.0000000000000000000007396 97.0
HKD1_k127_1785189_84 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0000000000000000001078 91.0
HKD1_k127_1785189_85 YceI-like domain - - - 0.0000000000000000003589 97.0
HKD1_k127_1785189_86 - - - - 0.000000000000000001805 93.0
HKD1_k127_1785189_88 - - - - 0.00000000000000006191 88.0
HKD1_k127_1785189_89 Polymer-forming cytoskeletal - - - 0.0000000000000006226 83.0
HKD1_k127_1785189_9 DNA topological change K03168 - 5.99.1.2 3.562e-220 713.0
HKD1_k127_1785189_90 Outer membrane protein beta-barrel domain - - - 0.000000000000000765 91.0
HKD1_k127_1785189_91 - - - - 0.0000000000001259 78.0
HKD1_k127_1785189_92 - - - - 0.0000000000004944 78.0
HKD1_k127_1785189_93 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000003832 69.0
HKD1_k127_1785189_94 - - - - 0.0000000001964 73.0
HKD1_k127_1785189_95 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000007318 72.0
HKD1_k127_1785189_96 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000009634 69.0
HKD1_k127_1785189_97 NHL repeat - - - 0.000000002817 64.0
HKD1_k127_1785189_98 - - - - 0.000000007509 60.0
HKD1_k127_1785189_99 - - - - 0.00000002088 65.0
HKD1_k127_183228_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1172.0
HKD1_k127_183228_1 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.0 1138.0
HKD1_k127_183228_10 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 476.0
HKD1_k127_183228_11 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 464.0
HKD1_k127_183228_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 442.0
HKD1_k127_183228_13 nadh flavin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 438.0
HKD1_k127_183228_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 431.0
HKD1_k127_183228_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 428.0
HKD1_k127_183228_16 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 407.0
HKD1_k127_183228_17 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 406.0
HKD1_k127_183228_18 PEP-utilising enzyme, N-terminal K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 406.0
HKD1_k127_183228_19 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 401.0
HKD1_k127_183228_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.802e-266 840.0
HKD1_k127_183228_20 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 366.0
HKD1_k127_183228_21 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 368.0
HKD1_k127_183228_22 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 367.0
HKD1_k127_183228_23 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 350.0
HKD1_k127_183228_24 PFAM WD40 domain protein beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 375.0
HKD1_k127_183228_25 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 347.0
HKD1_k127_183228_26 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 348.0
HKD1_k127_183228_27 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 332.0
HKD1_k127_183228_28 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 319.0
HKD1_k127_183228_29 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 292.0
HKD1_k127_183228_3 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.725e-257 822.0
HKD1_k127_183228_30 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
HKD1_k127_183228_31 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 290.0
HKD1_k127_183228_32 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 296.0
HKD1_k127_183228_33 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
HKD1_k127_183228_34 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005873 293.0
HKD1_k127_183228_35 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005998 285.0
HKD1_k127_183228_36 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005261 264.0
HKD1_k127_183228_37 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 259.0
HKD1_k127_183228_38 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000003968 262.0
HKD1_k127_183228_39 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
HKD1_k127_183228_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.566e-202 646.0
HKD1_k127_183228_40 Hydrolase, tatd K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000001936 232.0
HKD1_k127_183228_41 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000002018 241.0
HKD1_k127_183228_42 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000001542 223.0
HKD1_k127_183228_43 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000658 219.0
HKD1_k127_183228_44 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000005651 209.0
HKD1_k127_183228_45 Phosphotransferase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000003891 225.0
HKD1_k127_183228_46 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000003445 204.0
HKD1_k127_183228_47 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000006628 197.0
HKD1_k127_183228_48 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000007225 203.0
HKD1_k127_183228_49 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000001322 202.0
HKD1_k127_183228_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.069e-198 642.0
HKD1_k127_183228_50 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.000000000000000000000000000000000000000000000000000009214 198.0
HKD1_k127_183228_51 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000153 209.0
HKD1_k127_183228_52 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000004343 201.0
HKD1_k127_183228_53 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000001753 196.0
HKD1_k127_183228_54 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000003756 213.0
HKD1_k127_183228_55 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000219 171.0
HKD1_k127_183228_56 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000006974 167.0
HKD1_k127_183228_57 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000002505 174.0
HKD1_k127_183228_58 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000003933 164.0
HKD1_k127_183228_59 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000004279 142.0
HKD1_k127_183228_6 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 631.0
HKD1_k127_183228_60 PHP domain protein - - - 0.00000000000000000000000000000000008658 152.0
HKD1_k127_183228_61 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000001319 135.0
HKD1_k127_183228_62 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000000001068 129.0
HKD1_k127_183228_63 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000004747 128.0
HKD1_k127_183228_64 methyltransferase - - - 0.0000000000000000000000000492 118.0
HKD1_k127_183228_65 PFAM Peptidase M22, glycoprotease - - - 0.000000000000000000000004943 110.0
HKD1_k127_183228_66 lipopolysaccharide transport K09774 - - 0.000000000000000000004249 109.0
HKD1_k127_183228_67 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000103 97.0
HKD1_k127_183228_68 Phosphotransferase System K11189 - - 0.00000000000000000005229 92.0
HKD1_k127_183228_69 PQQ enzyme repeat K17713 - - 0.00000000000000004991 96.0
HKD1_k127_183228_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 544.0
HKD1_k127_183228_70 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000005732 86.0
HKD1_k127_183228_71 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000005609 80.0
HKD1_k127_183228_72 general secretion pathway protein K02456,K02650 - - 0.000000000000001326 88.0
HKD1_k127_183228_73 pfam yhs - - - 0.00000000000001421 74.0
HKD1_k127_183228_74 Outer membrane lipoprotein - - - 0.00000000000002322 84.0
HKD1_k127_183228_75 - - - - 0.0000000001018 69.0
HKD1_k127_183228_76 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000002922 62.0
HKD1_k127_183228_78 PFAM PKD domain containing protein - - - 0.000149 54.0
HKD1_k127_183228_79 Protein of unknown function (DUF465) - - - 0.0002427 46.0
HKD1_k127_183228_8 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 544.0
HKD1_k127_183228_80 TonB C terminal K03832 - - 0.0008612 50.0
HKD1_k127_183228_9 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 527.0
HKD1_k127_1865698_0 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002354 224.0
HKD1_k127_1865698_1 COG2867 Oligoketide cyclase lipid transport protein - GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000001271 149.0
HKD1_k127_1865698_2 HAF family - - - 0.00000000000000000000000000000000692 142.0
HKD1_k127_1865698_3 Laminin G domain - - - 0.000000000000005944 87.0
HKD1_k127_1904447_0 PFAM Transposase - - - 0.00000000000000000000000000000000000000000000000000000003955 215.0
HKD1_k127_2101880_0 - - - - 0.00000000000000000000000000000000000000000000000000004753 192.0
HKD1_k127_2101880_1 DNA-binding transcription factor activity - - - 0.00000000000000000000000003211 112.0
HKD1_k127_2132600_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 347.0
HKD1_k127_2132600_1 HlyD membrane-fusion protein of T1SS K03585 - - 0.00000000000000000000000000000000000000000000214 171.0
HKD1_k127_2136400_0 Dehydrogenase K00117 - 1.1.5.2 1.132e-289 905.0
HKD1_k127_2136400_1 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 1.411e-275 856.0
HKD1_k127_2136400_10 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 307.0
HKD1_k127_2136400_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 292.0
HKD1_k127_2136400_13 - - - - 0.000000000000000000000000000000000000000000000000000000000009736 219.0
HKD1_k127_2136400_14 - - - - 0.00000000000000000000000000000000000000000000000000000000001692 218.0
HKD1_k127_2136400_15 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000004793 207.0
HKD1_k127_2136400_16 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000002651 182.0
HKD1_k127_2136400_17 - - - - 0.00000000000000000000000000000000000000001817 158.0
HKD1_k127_2136400_18 - - - - 0.000000000000000000000000000000000000002069 156.0
HKD1_k127_2136400_19 - - - - 0.00000000000000000000000000000005979 141.0
HKD1_k127_2136400_2 - - - - 3.41e-247 788.0
HKD1_k127_2136400_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000001299 121.0
HKD1_k127_2136400_21 Methyltransferase - - - 0.0000000000000000000002717 106.0
HKD1_k127_2136400_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000004924 60.0
HKD1_k127_2136400_3 Protein tyrosine kinase K12132 - 2.7.11.1 1.243e-241 783.0
HKD1_k127_2136400_4 alcohol dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 524.0
HKD1_k127_2136400_5 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 494.0
HKD1_k127_2136400_6 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 426.0
HKD1_k127_2136400_7 domain, Protein K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 396.0
HKD1_k127_2136400_8 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 363.0
HKD1_k127_2136400_9 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 321.0
HKD1_k127_2197311_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000002814 196.0
HKD1_k127_2197311_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000008807 192.0
HKD1_k127_2197311_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000003264 72.0
HKD1_k127_2197311_3 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0002418 49.0
HKD1_k127_2217359_0 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 514.0
HKD1_k127_2217359_1 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
HKD1_k127_2217359_10 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000008922 121.0
HKD1_k127_2217359_11 carboxymuconolactone decarboxylase - - - 0.0000000000000000000002981 111.0
HKD1_k127_2217359_12 - - - - 0.000000000000000004989 97.0
HKD1_k127_2217359_13 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000257 74.0
HKD1_k127_2217359_14 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000713 53.0
HKD1_k127_2217359_2 COG4993 Glucose dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 383.0
HKD1_k127_2217359_3 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
HKD1_k127_2217359_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008873 292.0
HKD1_k127_2217359_5 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
HKD1_k127_2217359_6 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002023 262.0
HKD1_k127_2217359_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000004312 151.0
HKD1_k127_2217359_8 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000002295 128.0
HKD1_k127_2217359_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000004344 129.0
HKD1_k127_2328487_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1096.0
HKD1_k127_2328487_1 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.008e-266 843.0
HKD1_k127_2328487_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 417.0
HKD1_k127_2328487_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 382.0
HKD1_k127_2328487_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
HKD1_k127_2328487_13 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 367.0
HKD1_k127_2328487_14 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 364.0
HKD1_k127_2328487_15 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 370.0
HKD1_k127_2328487_16 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
HKD1_k127_2328487_17 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 321.0
HKD1_k127_2328487_18 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 312.0
HKD1_k127_2328487_19 MucB/RseB N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 316.0
HKD1_k127_2328487_2 - - - - 5.001e-216 691.0
HKD1_k127_2328487_20 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 300.0
HKD1_k127_2328487_21 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 295.0
HKD1_k127_2328487_22 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 295.0
HKD1_k127_2328487_23 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005014 293.0
HKD1_k127_2328487_24 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001884 282.0
HKD1_k127_2328487_25 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000002727 245.0
HKD1_k127_2328487_26 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000001305 217.0
HKD1_k127_2328487_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000001335 221.0
HKD1_k127_2328487_28 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000003413 188.0
HKD1_k127_2328487_29 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000001304 160.0
HKD1_k127_2328487_3 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 584.0
HKD1_k127_2328487_30 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000003553 172.0
HKD1_k127_2328487_31 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002603 147.0
HKD1_k127_2328487_32 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000001979 141.0
HKD1_k127_2328487_33 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000004507 119.0
HKD1_k127_2328487_34 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000233 125.0
HKD1_k127_2328487_35 WHG domain - - - 0.000000000000000000000001083 112.0
HKD1_k127_2328487_37 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000008839 99.0
HKD1_k127_2328487_38 - - - - 0.0000000000000000005084 91.0
HKD1_k127_2328487_39 - - - - 0.000000000000000006473 91.0
HKD1_k127_2328487_4 Dehydrogenase K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 567.0
HKD1_k127_2328487_40 unfolded protein binding K06142 - - 0.00000000652 66.0
HKD1_k127_2328487_41 Predicted membrane protein (DUF2085) - - - 0.0000006251 57.0
HKD1_k127_2328487_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 554.0
HKD1_k127_2328487_6 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 458.0
HKD1_k127_2328487_7 FtsX-like permease family K02004,K05685,K09808,K11636 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 439.0
HKD1_k127_2328487_8 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 420.0
HKD1_k127_2328487_9 MacB-like periplasmic core domain K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 419.0
HKD1_k127_2353306_0 Transposase, Mutator family K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 525.0
HKD1_k127_2353306_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005441 272.0
HKD1_k127_2356496_0 TonB dependent receptor - - - 1.552e-205 664.0
HKD1_k127_2356496_1 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 9.751e-199 633.0
HKD1_k127_2356496_10 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 295.0
HKD1_k127_2356496_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 300.0
HKD1_k127_2356496_12 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HKD1_k127_2356496_13 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003 296.0
HKD1_k127_2356496_14 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008164 273.0
HKD1_k127_2356496_15 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
HKD1_k127_2356496_16 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000239 257.0
HKD1_k127_2356496_17 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001397 257.0
HKD1_k127_2356496_18 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000007677 239.0
HKD1_k127_2356496_19 HpcH/HpaI aldolase/citrate lyase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
HKD1_k127_2356496_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 587.0
HKD1_k127_2356496_20 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000003819 231.0
HKD1_k127_2356496_21 - - - - 0.00000000000000000000000000000000000000000000000000000001976 209.0
HKD1_k127_2356496_22 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000001177 208.0
HKD1_k127_2356496_23 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000002639 193.0
HKD1_k127_2356496_24 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000003293 164.0
HKD1_k127_2356496_25 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000001988 146.0
HKD1_k127_2356496_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000312 142.0
HKD1_k127_2356496_27 coenzyme binding K07071 - - 0.00000000000000000000000000000000001238 145.0
HKD1_k127_2356496_28 COG0666 FOG Ankyrin repeat K06867 - - 0.0000000000000000000000000000001279 138.0
HKD1_k127_2356496_29 - - - - 0.0000000000000000000000000000003863 133.0
HKD1_k127_2356496_3 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 534.0
HKD1_k127_2356496_30 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000004129 143.0
HKD1_k127_2356496_31 DinB family - - - 0.00000000000000000000000000001948 123.0
HKD1_k127_2356496_32 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000002281 108.0
HKD1_k127_2356496_33 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000045 116.0
HKD1_k127_2356496_34 Haem-binding domain - - - 0.00000000000000000000006039 104.0
HKD1_k127_2356496_35 YXWGXW repeat (2 copies) - - - 0.0000000000000000001286 99.0
HKD1_k127_2356496_36 - - - - 0.00000000000000007492 88.0
HKD1_k127_2356496_37 Pfam:DUF2029 - - - 0.000000000000000265 91.0
HKD1_k127_2356496_38 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000001497 80.0
HKD1_k127_2356496_39 esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000002496 85.0
HKD1_k127_2356496_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 430.0
HKD1_k127_2356496_40 Protein of unknown function (DUF983) - - - 0.000000000002557 74.0
HKD1_k127_2356496_41 Nad-dependent epimerase dehydratase - - - 0.00000002085 59.0
HKD1_k127_2356496_42 dihydroorotate dehydrogenase activity - - - 0.00001416 54.0
HKD1_k127_2356496_43 - - - - 0.00003326 56.0
HKD1_k127_2356496_5 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 406.0
HKD1_k127_2356496_6 oligopeptide transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 397.0
HKD1_k127_2356496_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 374.0
HKD1_k127_2356496_8 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 318.0
HKD1_k127_2356496_9 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
HKD1_k127_2370751_0 DEAD DEAH box K03724 - - 0.0 1780.0
HKD1_k127_2370751_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.198e-252 789.0
HKD1_k127_2370751_10 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 526.0
HKD1_k127_2370751_11 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 507.0
HKD1_k127_2370751_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 504.0
HKD1_k127_2370751_13 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 501.0
HKD1_k127_2370751_14 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 504.0
HKD1_k127_2370751_15 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 499.0
HKD1_k127_2370751_16 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 482.0
HKD1_k127_2370751_17 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 474.0
HKD1_k127_2370751_18 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 481.0
HKD1_k127_2370751_19 NAD binding K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 452.0
HKD1_k127_2370751_2 COG0644 Dehydrogenases (flavoproteins) - - - 9.277e-212 665.0
HKD1_k127_2370751_20 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 440.0
HKD1_k127_2370751_21 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 428.0
HKD1_k127_2370751_22 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 420.0
HKD1_k127_2370751_23 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
HKD1_k127_2370751_24 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 385.0
HKD1_k127_2370751_25 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 381.0
HKD1_k127_2370751_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 374.0
HKD1_k127_2370751_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 369.0
HKD1_k127_2370751_28 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 355.0
HKD1_k127_2370751_29 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 357.0
HKD1_k127_2370751_3 FtsX-like permease family - - - 1.122e-199 662.0
HKD1_k127_2370751_30 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 342.0
HKD1_k127_2370751_31 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 334.0
HKD1_k127_2370751_32 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 333.0
HKD1_k127_2370751_33 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 310.0
HKD1_k127_2370751_34 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 320.0
HKD1_k127_2370751_35 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 312.0
HKD1_k127_2370751_36 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 301.0
HKD1_k127_2370751_37 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003102 300.0
HKD1_k127_2370751_38 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000202 301.0
HKD1_k127_2370751_39 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004574 262.0
HKD1_k127_2370751_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 5.78e-199 625.0
HKD1_k127_2370751_40 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001667 251.0
HKD1_k127_2370751_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002343 248.0
HKD1_k127_2370751_42 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001537 247.0
HKD1_k127_2370751_43 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000005177 233.0
HKD1_k127_2370751_44 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000001131 232.0
HKD1_k127_2370751_45 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000007073 206.0
HKD1_k127_2370751_46 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008069 201.0
HKD1_k127_2370751_47 Pfam:Y_phosphatase3C K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000006645 205.0
HKD1_k127_2370751_48 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000003502 199.0
HKD1_k127_2370751_49 O-Antigen ligase K18814 - - 0.00000000000000000000000000000000000000000000000000001087 205.0
HKD1_k127_2370751_5 COG1012 NAD-dependent aldehyde - - - 5.666e-198 627.0
HKD1_k127_2370751_50 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000002257 190.0
HKD1_k127_2370751_51 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000003691 196.0
HKD1_k127_2370751_52 Glycosyl transferase, family 9 K02843,K02849 - - 0.00000000000000000000000000000000000000000000000003238 193.0
HKD1_k127_2370751_53 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000008821 185.0
HKD1_k127_2370751_54 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000001399 181.0
HKD1_k127_2370751_55 - - - - 0.0000000000000000000000000000000000000000000000328 184.0
HKD1_k127_2370751_56 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000005416 178.0
HKD1_k127_2370751_57 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000009981 176.0
HKD1_k127_2370751_58 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000005133 167.0
HKD1_k127_2370751_59 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000003134 167.0
HKD1_k127_2370751_6 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 612.0
HKD1_k127_2370751_60 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000006421 154.0
HKD1_k127_2370751_61 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000002352 144.0
HKD1_k127_2370751_62 Haem-degrading - - - 0.000000000000000000000000000000000000462 146.0
HKD1_k127_2370751_63 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000001216 139.0
HKD1_k127_2370751_64 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000002316 141.0
HKD1_k127_2370751_65 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000002268 132.0
HKD1_k127_2370751_66 GYD domain - - - 0.000000000000000000000000000003483 123.0
HKD1_k127_2370751_67 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000006469 125.0
HKD1_k127_2370751_68 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000001703 118.0
HKD1_k127_2370751_69 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000003717 114.0
HKD1_k127_2370751_7 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 574.0
HKD1_k127_2370751_70 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000006425 109.0
HKD1_k127_2370751_71 Thioesterase superfamily K07107 - - 0.0000000000000000000000002073 111.0
HKD1_k127_2370751_72 - - - - 0.000000000000000000000003245 108.0
HKD1_k127_2370751_74 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000001616 97.0
HKD1_k127_2370751_75 chorismate lyase activity - - - 0.0000000000000000000242 98.0
HKD1_k127_2370751_76 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002917 86.0
HKD1_k127_2370751_77 Trm112p-like protein K09791 - - 0.00000000000000005435 86.0
HKD1_k127_2370751_78 - - - - 0.00000000000001837 82.0
HKD1_k127_2370751_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 549.0
HKD1_k127_2370751_80 Protein of unknown function (DUF3311) - - - 0.000000134 56.0
HKD1_k127_2370751_82 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003721 53.0
HKD1_k127_2370751_83 beta-propeller repeat - - - 0.000007976 48.0
HKD1_k127_2370751_85 - - - - 0.0005125 49.0
HKD1_k127_2370751_9 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 533.0
HKD1_k127_2373272_0 efflux transmembrane transporter activity - - - 4.618e-313 978.0
HKD1_k127_2373272_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 589.0
HKD1_k127_2373272_10 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 379.0
HKD1_k127_2373272_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 360.0
HKD1_k127_2373272_12 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
HKD1_k127_2373272_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 316.0
HKD1_k127_2373272_14 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 293.0
HKD1_k127_2373272_15 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 284.0
HKD1_k127_2373272_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001585 277.0
HKD1_k127_2373272_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001735 254.0
HKD1_k127_2373272_18 - - - - 0.0000000000000000000000000000000000000000000000000003527 198.0
HKD1_k127_2373272_19 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000003129 180.0
HKD1_k127_2373272_2 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 555.0
HKD1_k127_2373272_20 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000001627 194.0
HKD1_k127_2373272_21 manganese ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000003667 184.0
HKD1_k127_2373272_22 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000004325 98.0
HKD1_k127_2373272_23 Protein of unknown function (DUF3108) - - - 0.0000000000000648 86.0
HKD1_k127_2373272_24 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000001311 62.0
HKD1_k127_2373272_25 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000001871 68.0
HKD1_k127_2373272_26 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000003319 61.0
HKD1_k127_2373272_27 PEGA domain - - - 0.00002851 55.0
HKD1_k127_2373272_28 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0002787 48.0
HKD1_k127_2373272_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 554.0
HKD1_k127_2373272_4 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 488.0
HKD1_k127_2373272_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 456.0
HKD1_k127_2373272_6 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 439.0
HKD1_k127_2373272_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 437.0
HKD1_k127_2373272_8 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 406.0
HKD1_k127_2373272_9 PFAM Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 398.0
HKD1_k127_2480293_0 PQQ-like domain - - - 2.789e-202 650.0
HKD1_k127_2480293_1 pyrroloquinoline quinone binding - - - 1.201e-198 638.0
HKD1_k127_2480293_10 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000002638 206.0
HKD1_k127_2480293_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000004966 172.0
HKD1_k127_2480293_12 - - - - 0.0000000000000000000000000000000000000000006823 171.0
HKD1_k127_2480293_13 Penicillinase repressor - - - 0.0000000000000000000000000000000000000005346 152.0
HKD1_k127_2480293_14 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000005385 143.0
HKD1_k127_2480293_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000005489 125.0
HKD1_k127_2480293_16 - - - - 0.0000000000000000002711 97.0
HKD1_k127_2480293_17 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000004822 76.0
HKD1_k127_2480293_18 antisigma factor binding - - - 0.00000001357 65.0
HKD1_k127_2480293_19 protein conserved in bacteria - - - 0.0001461 54.0
HKD1_k127_2480293_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 565.0
HKD1_k127_2480293_3 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
HKD1_k127_2480293_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 399.0
HKD1_k127_2480293_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 297.0
HKD1_k127_2480293_6 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008925 268.0
HKD1_k127_2480293_7 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
HKD1_k127_2480293_8 - - - - 0.0000000000000000000000000000000000000000000000000000000004841 215.0
HKD1_k127_2480293_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
HKD1_k127_249131_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.864e-242 780.0
HKD1_k127_249131_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 546.0
HKD1_k127_249131_10 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000003452 119.0
HKD1_k127_249131_11 - - - - 0.000000000000000000000000315 111.0
HKD1_k127_249131_12 - - - - 0.0000000000000000000000004279 116.0
HKD1_k127_249131_13 Surface antigen - - - 0.00000000000000000002813 104.0
HKD1_k127_249131_14 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.00000000000000000003156 101.0
HKD1_k127_249131_15 - - - - 0.000000000000000002609 93.0
HKD1_k127_249131_16 - - - - 0.000000000000000004259 89.0
HKD1_k127_249131_17 - - - - 0.0000000000000004385 89.0
HKD1_k127_249131_19 Domain of unknown function (DUF4136) - - - 0.000001431 57.0
HKD1_k127_249131_2 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 535.0
HKD1_k127_249131_20 PFAM CHAD domain containing protein - - - 0.000005176 59.0
HKD1_k127_249131_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 458.0
HKD1_k127_249131_4 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 386.0
HKD1_k127_249131_5 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 306.0
HKD1_k127_249131_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001137 255.0
HKD1_k127_249131_7 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000002158 191.0
HKD1_k127_249131_8 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000892 192.0
HKD1_k127_249131_9 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000001171 132.0
HKD1_k127_2516581_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000007701 221.0
HKD1_k127_2516581_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002764 200.0
HKD1_k127_2540351_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.787e-265 836.0
HKD1_k127_2540351_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 1.033e-234 749.0
HKD1_k127_2540351_10 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000002446 184.0
HKD1_k127_2540351_11 Dienelactone hydrolase family K07018 - - 0.000000000000000000000000000000000000000009982 162.0
HKD1_k127_2540351_12 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000001719 126.0
HKD1_k127_2540351_13 Yqey-like protein K09117 - - 0.0000000000000000000000000001626 129.0
HKD1_k127_2540351_14 Alpha/beta hydrolase family - - - 0.00000000000009133 83.0
HKD1_k127_2540351_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 451.0
HKD1_k127_2540351_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 443.0
HKD1_k127_2540351_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 392.0
HKD1_k127_2540351_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 370.0
HKD1_k127_2540351_6 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 338.0
HKD1_k127_2540351_7 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
HKD1_k127_2540351_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001315 274.0
HKD1_k127_2540351_9 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000005318 245.0
HKD1_k127_2564937_0 DEAD DEAH box helicase K03724 - - 0.0 1482.0
HKD1_k127_2564937_1 Carboxypeptidase regulatory-like domain - - - 0.0 1109.0
HKD1_k127_2564937_10 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 310.0
HKD1_k127_2564937_11 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009113 248.0
HKD1_k127_2564937_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001067 215.0
HKD1_k127_2564937_13 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000001902 229.0
HKD1_k127_2564937_14 - - - - 0.0000000000000000000000000000000000000000000000000000000004683 216.0
HKD1_k127_2564937_15 cytochrome K08738 - - 0.0000000000000000000000000000000000000000000000000000002689 201.0
HKD1_k127_2564937_16 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K13524 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000006735 201.0
HKD1_k127_2564937_17 AMP binding - - - 0.000000000000000000000000000000000000000000000003774 183.0
HKD1_k127_2564937_18 TIGRFAM DNA binding domain protein, excisionase family - - - 0.00000000000000000000000000000001547 131.0
HKD1_k127_2564937_19 hydroperoxide reductase activity - - - 0.000000000000000000000000001052 115.0
HKD1_k127_2564937_2 PFAM AMP-dependent synthetase and ligase K00666 - - 4.136e-233 734.0
HKD1_k127_2564937_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000005799 116.0
HKD1_k127_2564937_21 PFAM von Willebrand factor type A - - - 0.00000000000000000000066 107.0
HKD1_k127_2564937_22 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000007085 99.0
HKD1_k127_2564937_23 hydroperoxide reductase activity - - - 0.000000000000000001123 93.0
HKD1_k127_2564937_24 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000001212 84.0
HKD1_k127_2564937_26 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000003637 68.0
HKD1_k127_2564937_27 - - - - 0.0000000001512 68.0
HKD1_k127_2564937_28 - - - - 0.00000002568 61.0
HKD1_k127_2564937_29 Iron permease - - - 0.00005735 51.0
HKD1_k127_2564937_3 Periplasmic binding protein domain K01999 - - 3.457e-231 722.0
HKD1_k127_2564937_4 antibiotic catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 549.0
HKD1_k127_2564937_5 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 509.0
HKD1_k127_2564937_6 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 465.0
HKD1_k127_2564937_7 short chain amide porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 344.0
HKD1_k127_2564937_8 ABC transporter K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 307.0
HKD1_k127_2564937_9 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 300.0
HKD1_k127_2571687_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 273.0
HKD1_k127_2571687_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001083 279.0
HKD1_k127_2734465_0 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 439.0
HKD1_k127_2734465_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 403.0
HKD1_k127_2734465_10 Mechanosensitive ion channel K22044 - - 0.0000000006938 68.0
HKD1_k127_2734465_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 393.0
HKD1_k127_2734465_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 382.0
HKD1_k127_2734465_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 333.0
HKD1_k127_2734465_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 307.0
HKD1_k127_2734465_6 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 311.0
HKD1_k127_2734465_7 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000481 220.0
HKD1_k127_2734465_8 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000001097 219.0
HKD1_k127_2734465_9 O-methyltransferase - - - 0.0000000000000000000000000000000000006571 151.0
HKD1_k127_27358_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 464.0
HKD1_k127_27358_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
HKD1_k127_290348_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 351.0
HKD1_k127_290348_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 341.0
HKD1_k127_2912587_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1032.0
HKD1_k127_2912587_1 MacB-like periplasmic core domain - - - 3.107e-313 979.0
HKD1_k127_2912587_10 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 488.0
HKD1_k127_2912587_11 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 484.0
HKD1_k127_2912587_12 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 485.0
HKD1_k127_2912587_13 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 473.0
HKD1_k127_2912587_14 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 409.0
HKD1_k127_2912587_15 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 355.0
HKD1_k127_2912587_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 343.0
HKD1_k127_2912587_17 SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 337.0
HKD1_k127_2912587_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 338.0
HKD1_k127_2912587_19 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 279.0
HKD1_k127_2912587_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 2.63e-298 929.0
HKD1_k127_2912587_20 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002013 277.0
HKD1_k127_2912587_21 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000002371 277.0
HKD1_k127_2912587_22 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006396 265.0
HKD1_k127_2912587_23 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000003486 229.0
HKD1_k127_2912587_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
HKD1_k127_2912587_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000001754 208.0
HKD1_k127_2912587_26 Ankyrin repeats (3 copies) - - - 0.000000000000000000000000000000000000000000000000000007492 209.0
HKD1_k127_2912587_27 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000001016 197.0
HKD1_k127_2912587_28 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001615 175.0
HKD1_k127_2912587_29 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000003649 172.0
HKD1_k127_2912587_3 ABC-type multidrug transport system ATPase and permease K06147 - - 1.489e-296 920.0
HKD1_k127_2912587_30 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000001189 143.0
HKD1_k127_2912587_31 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000002466 143.0
HKD1_k127_2912587_32 protein maturation K13628 - - 0.00000000000000000000000000000000007983 136.0
HKD1_k127_2912587_33 drug resistance transporter, EmrB QacA subfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000008746 127.0
HKD1_k127_2912587_34 Methyltransferase type 11 - - - 0.0000000000000000000000000000001631 134.0
HKD1_k127_2912587_35 Hydrolase, NUDIX family K01515 - 3.6.1.13 0.00000000000000000000000000001055 133.0
HKD1_k127_2912587_36 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000005095 126.0
HKD1_k127_2912587_37 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000001186 121.0
HKD1_k127_2912587_38 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000001402 127.0
HKD1_k127_2912587_39 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000001275 113.0
HKD1_k127_2912587_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.845e-281 889.0
HKD1_k127_2912587_40 Belongs to the Fur family K03711 - - 0.0000000000000000000000001898 117.0
HKD1_k127_2912587_41 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000002948 110.0
HKD1_k127_2912587_42 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000682 96.0
HKD1_k127_2912587_43 TIGRFAM TonB family K03832 - - 0.000000000000000000001403 97.0
HKD1_k127_2912587_44 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000003898 98.0
HKD1_k127_2912587_45 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000005369 94.0
HKD1_k127_2912587_46 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001096 89.0
HKD1_k127_2912587_47 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.0000000000000001246 83.0
HKD1_k127_2912587_48 ABC transporter K02003 - - 0.0000000000000005701 89.0
HKD1_k127_2912587_49 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000003811 78.0
HKD1_k127_2912587_5 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 1.17e-253 796.0
HKD1_k127_2912587_50 - - - - 0.0000000000003406 78.0
HKD1_k127_2912587_51 Cold shock protein domain - - - 0.000000000003181 70.0
HKD1_k127_2912587_52 - - - - 0.00003487 52.0
HKD1_k127_2912587_53 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00003844 55.0
HKD1_k127_2912587_54 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0009174 44.0
HKD1_k127_2912587_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.024e-243 771.0
HKD1_k127_2912587_7 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.657e-227 713.0
HKD1_k127_2912587_8 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 581.0
HKD1_k127_2912587_9 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 558.0
HKD1_k127_296754_0 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 555.0
HKD1_k127_296754_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 452.0
HKD1_k127_296754_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000003072 139.0
HKD1_k127_296754_11 rod shape-determining protein MreD K03571 - - 0.0001873 51.0
HKD1_k127_296754_2 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 379.0
HKD1_k127_296754_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 314.0
HKD1_k127_296754_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002378 274.0
HKD1_k127_296754_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001543 238.0
HKD1_k127_296754_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000003966 199.0
HKD1_k127_296754_8 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000001018 188.0
HKD1_k127_296754_9 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000002347 147.0
HKD1_k127_3029910_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.036e-270 849.0
HKD1_k127_3029910_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.007e-252 797.0
HKD1_k127_3029910_10 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 489.0
HKD1_k127_3029910_11 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 475.0
HKD1_k127_3029910_12 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 490.0
HKD1_k127_3029910_13 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 458.0
HKD1_k127_3029910_14 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 455.0
HKD1_k127_3029910_15 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 454.0
HKD1_k127_3029910_16 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 443.0
HKD1_k127_3029910_17 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 438.0
HKD1_k127_3029910_18 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 424.0
HKD1_k127_3029910_19 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 397.0
HKD1_k127_3029910_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.047e-235 759.0
HKD1_k127_3029910_20 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 388.0
HKD1_k127_3029910_21 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 378.0
HKD1_k127_3029910_22 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 416.0
HKD1_k127_3029910_23 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 372.0
HKD1_k127_3029910_24 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 365.0
HKD1_k127_3029910_25 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 354.0
HKD1_k127_3029910_26 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
HKD1_k127_3029910_27 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 312.0
HKD1_k127_3029910_28 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 297.0
HKD1_k127_3029910_29 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000148 297.0
HKD1_k127_3029910_3 PQQ-like domain - - - 1.462e-218 697.0
HKD1_k127_3029910_30 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001601 289.0
HKD1_k127_3029910_31 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005506 308.0
HKD1_k127_3029910_32 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002513 301.0
HKD1_k127_3029910_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001644 280.0
HKD1_k127_3029910_34 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000006629 269.0
HKD1_k127_3029910_35 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000225 259.0
HKD1_k127_3029910_36 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002392 268.0
HKD1_k127_3029910_37 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
HKD1_k127_3029910_38 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000006804 247.0
HKD1_k127_3029910_39 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
HKD1_k127_3029910_4 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 2.804e-199 632.0
HKD1_k127_3029910_40 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004075 252.0
HKD1_k127_3029910_41 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
HKD1_k127_3029910_42 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000009721 225.0
HKD1_k127_3029910_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000001708 215.0
HKD1_k127_3029910_44 - - - - 0.0000000000000000000000000000000000000000000000000000000238 206.0
HKD1_k127_3029910_45 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000004216 202.0
HKD1_k127_3029910_46 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000004369 208.0
HKD1_k127_3029910_47 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000003492 206.0
HKD1_k127_3029910_48 - - - - 0.0000000000000000000000000000000000000000000000000002454 198.0
HKD1_k127_3029910_49 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000005904 204.0
HKD1_k127_3029910_5 Carboxypeptidase regulatory-like domain - - - 1.709e-197 640.0
HKD1_k127_3029910_50 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003047 196.0
HKD1_k127_3029910_52 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000009666 179.0
HKD1_k127_3029910_53 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000005781 173.0
HKD1_k127_3029910_54 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000006635 171.0
HKD1_k127_3029910_55 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000003078 164.0
HKD1_k127_3029910_56 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000001615 160.0
HKD1_k127_3029910_57 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000002525 152.0
HKD1_k127_3029910_58 - - - - 0.000000000000000000000000000000000001716 147.0
HKD1_k127_3029910_59 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000003424 148.0
HKD1_k127_3029910_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 5.289e-194 618.0
HKD1_k127_3029910_60 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006374 133.0
HKD1_k127_3029910_61 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000001836 133.0
HKD1_k127_3029910_62 COG4257 Streptogramin lyase K18235 - - 0.0000000000000000000000000002339 132.0
HKD1_k127_3029910_63 CYTH K05873 - 4.6.1.1 0.000000000000000000000000006893 118.0
HKD1_k127_3029910_64 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000008083 112.0
HKD1_k127_3029910_65 Pfam:N_methyl_2 - - - 0.00000000000000000003633 98.0
HKD1_k127_3029910_66 Belongs to the ompA family K03640 - - 0.00000000000000000003993 105.0
HKD1_k127_3029910_68 - - - - 0.000000000000000003969 90.0
HKD1_k127_3029910_69 Protein of unknown function (DUF503) K09764 - - 0.000000000000000004408 87.0
HKD1_k127_3029910_7 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 595.0
HKD1_k127_3029910_70 Cupin 2, conserved barrel domain protein - - - 0.00000000000000001852 89.0
HKD1_k127_3029910_71 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000001137 81.0
HKD1_k127_3029910_73 Thioredoxin - - - 0.00000000000003979 85.0
HKD1_k127_3029910_74 Flagellar outer dynein arm heavy chain gamma K10408 - - 0.00000000000008058 86.0
HKD1_k127_3029910_75 Polymer-forming cytoskeletal - - - 0.00000000001239 77.0
HKD1_k127_3029910_76 - - - - 0.00000000005309 71.0
HKD1_k127_3029910_77 Cupin 2, conserved barrel domain protein K11477 - - 0.00000005064 62.0
HKD1_k127_3029910_78 - - - - 0.00000007102 63.0
HKD1_k127_3029910_79 pilus assembly protein PilW K02672 - - 0.00004474 56.0
HKD1_k127_3029910_8 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 522.0
HKD1_k127_3029910_80 beta-lactamase - - - 0.00005384 48.0
HKD1_k127_3029910_81 Prokaryotic N-terminal methylation motif K02671 - - 0.000394 51.0
HKD1_k127_3029910_82 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0008962 48.0
HKD1_k127_3029910_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 494.0
HKD1_k127_3062015_0 carnitine dehydratase - - - 1.354e-287 904.0
HKD1_k127_3062015_1 WD40-like Beta Propeller Repeat - - - 3.263e-226 736.0
HKD1_k127_3062015_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 386.0
HKD1_k127_3062015_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 396.0
HKD1_k127_3062015_12 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
HKD1_k127_3062015_13 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 361.0
HKD1_k127_3062015_14 conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 356.0
HKD1_k127_3062015_15 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 347.0
HKD1_k127_3062015_16 daunorubicin resistance ABC transporter membrane protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 344.0
HKD1_k127_3062015_17 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 314.0
HKD1_k127_3062015_18 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 300.0
HKD1_k127_3062015_19 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 291.0
HKD1_k127_3062015_2 PQQ-like domain - - - 4.787e-201 651.0
HKD1_k127_3062015_20 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
HKD1_k127_3062015_21 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002467 255.0
HKD1_k127_3062015_22 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005533 237.0
HKD1_k127_3062015_23 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000001172 240.0
HKD1_k127_3062015_24 HlyD family secretion protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000003195 232.0
HKD1_k127_3062015_25 - - - - 0.00000000000000000000000000000000000000000000000002923 194.0
HKD1_k127_3062015_26 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003714 188.0
HKD1_k127_3062015_27 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000005028 181.0
HKD1_k127_3062015_28 NHL repeat - - - 0.00000000000000000000000000000000000000000000001267 186.0
HKD1_k127_3062015_29 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000001799 181.0
HKD1_k127_3062015_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 1.987e-194 617.0
HKD1_k127_3062015_30 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000003934 185.0
HKD1_k127_3062015_31 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000005827 171.0
HKD1_k127_3062015_32 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000008091 136.0
HKD1_k127_3062015_33 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000002149 126.0
HKD1_k127_3062015_34 DinB superfamily - - - 0.000000000000000000000000000007799 131.0
HKD1_k127_3062015_35 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000002169 130.0
HKD1_k127_3062015_36 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.00000000000000000000000002886 117.0
HKD1_k127_3062015_37 AntiSigma factor - - - 0.000000000000000000000001982 115.0
HKD1_k127_3062015_38 - - - - 0.00000000000000000000008167 103.0
HKD1_k127_3062015_39 - - - - 0.0000000000000000000224 100.0
HKD1_k127_3062015_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 586.0
HKD1_k127_3062015_40 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000003765 94.0
HKD1_k127_3062015_41 Protein conserved in bacteria - - - 0.000000000000008877 81.0
HKD1_k127_3062015_42 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000003023 75.0
HKD1_k127_3062015_43 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000006308 81.0
HKD1_k127_3062015_44 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000009155 83.0
HKD1_k127_3062015_45 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000001581 76.0
HKD1_k127_3062015_47 PA14 - - - 0.000000002564 70.0
HKD1_k127_3062015_48 TadE-like protein - - - 0.0000000504 63.0
HKD1_k127_3062015_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 574.0
HKD1_k127_3062015_50 PFAM PKD domain containing protein - - - 0.000009879 56.0
HKD1_k127_3062015_51 Mo-co oxidoreductase dimerisation domain - - - 0.00001161 56.0
HKD1_k127_3062015_52 PIN domain - - - 0.00004623 51.0
HKD1_k127_3062015_54 positive regulation of growth - - - 0.000186 48.0
HKD1_k127_3062015_55 DNA-templated transcription, initiation K03088 - - 0.0003617 44.0
HKD1_k127_3062015_6 Multicopper K04753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 516.0
HKD1_k127_3062015_7 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 485.0
HKD1_k127_3062015_8 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 409.0
HKD1_k127_3062015_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 388.0
HKD1_k127_3080966_0 IgA Peptidase M64 - - - 0.000000000000000000006441 97.0
HKD1_k127_3080966_1 SnoaL-like domain - - - 0.00000000005773 70.0
HKD1_k127_3088607_0 PKS_KR - - - 0.0 2505.0
HKD1_k127_3088607_1 Aminotransferase class I and II - - - 2.851e-195 619.0
HKD1_k127_3088607_2 Alg9-like mannosyltransferase family K05286 - - 0.000000000000000000000000000000000000000004004 175.0
HKD1_k127_3088607_3 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.000000000000000000000000000000000002053 151.0
HKD1_k127_3088607_4 acetyltransferase - - - 0.000000000000000000000000000002568 123.0
HKD1_k127_3088607_5 - - - - 0.00000000008321 72.0
HKD1_k127_3103757_0 Periplasmic binding protein - - - 1.063e-202 638.0
HKD1_k127_3103757_1 Spirocyclase AveC-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 481.0
HKD1_k127_3103757_2 CbbQ NirQ NorQ C-terminal K04748 - - 0.000000000000000000003518 93.0
HKD1_k127_3154728_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 514.0
HKD1_k127_3154728_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 470.0
HKD1_k127_3154728_10 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000006431 193.0
HKD1_k127_3154728_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000002476 155.0
HKD1_k127_3154728_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000014 160.0
HKD1_k127_3154728_13 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000001871 128.0
HKD1_k127_3154728_14 PFAM Ankyrin repeat K06867 - - 0.000000000000000000000000000000968 139.0
HKD1_k127_3154728_15 TPM domain K06872 - - 0.000000000000000000000000001147 122.0
HKD1_k127_3154728_16 RNA recognition motif - - - 0.0000000000000000001145 96.0
HKD1_k127_3154728_17 nucleotidyltransferase activity - - - 0.0000000000000000216 94.0
HKD1_k127_3154728_18 helix_turn_helix, Lux Regulon - - - 0.00000000000002255 79.0
HKD1_k127_3154728_19 Stress-induced bacterial acidophilic repeat motif - - - 0.00000000000005012 80.0
HKD1_k127_3154728_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 400.0
HKD1_k127_3154728_20 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000002116 74.0
HKD1_k127_3154728_21 serine threonine protein kinase K12132 - 2.7.11.1 0.000002539 61.0
HKD1_k127_3154728_22 TonB-dependent Receptor Plug Domain - - - 0.00004689 55.0
HKD1_k127_3154728_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 336.0
HKD1_k127_3154728_4 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 303.0
HKD1_k127_3154728_5 MFS_1 like family K08151,K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005756 295.0
HKD1_k127_3154728_6 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002675 286.0
HKD1_k127_3154728_7 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001936 254.0
HKD1_k127_3154728_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000001433 221.0
HKD1_k127_3154728_9 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000003053 217.0
HKD1_k127_3183265_0 DNA topological change K03168 - 5.99.1.2 1.563e-229 729.0
HKD1_k127_3183265_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 486.0
HKD1_k127_3183265_2 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.0002564 48.0
HKD1_k127_3185662_0 oligopeptide transporter, OPT family - - - 1.585e-197 635.0
HKD1_k127_3185662_1 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 335.0
HKD1_k127_3185662_10 - - - - 0.000000000000000000000000000000000000000000000005595 186.0
HKD1_k127_3185662_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000003814 171.0
HKD1_k127_3185662_12 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000002173 160.0
HKD1_k127_3185662_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000001342 160.0
HKD1_k127_3185662_14 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000001724 156.0
HKD1_k127_3185662_15 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000006052 135.0
HKD1_k127_3185662_16 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000001243 127.0
HKD1_k127_3185662_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.0002294 44.0
HKD1_k127_3185662_2 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 288.0
HKD1_k127_3185662_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003512 258.0
HKD1_k127_3185662_5 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HKD1_k127_3185662_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000004866 214.0
HKD1_k127_3185662_7 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000002238 201.0
HKD1_k127_3185662_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001257 190.0
HKD1_k127_3185662_9 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000001129 186.0
HKD1_k127_3193577_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.003e-266 833.0
HKD1_k127_3193577_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 616.0
HKD1_k127_3193577_10 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 324.0
HKD1_k127_3193577_11 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 339.0
HKD1_k127_3193577_12 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 315.0
HKD1_k127_3193577_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
HKD1_k127_3193577_14 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 299.0
HKD1_k127_3193577_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004776 298.0
HKD1_k127_3193577_16 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 273.0
HKD1_k127_3193577_17 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 267.0
HKD1_k127_3193577_18 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003248 282.0
HKD1_k127_3193577_19 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 268.0
HKD1_k127_3193577_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 460.0
HKD1_k127_3193577_20 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005142 272.0
HKD1_k127_3193577_21 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003116 262.0
HKD1_k127_3193577_22 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004692 254.0
HKD1_k127_3193577_23 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000591 249.0
HKD1_k127_3193577_24 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000009837 241.0
HKD1_k127_3193577_25 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000001451 235.0
HKD1_k127_3193577_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000009446 224.0
HKD1_k127_3193577_27 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000002757 207.0
HKD1_k127_3193577_28 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000001619 196.0
HKD1_k127_3193577_29 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000001762 171.0
HKD1_k127_3193577_3 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 431.0
HKD1_k127_3193577_30 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000001063 169.0
HKD1_k127_3193577_31 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000006121 143.0
HKD1_k127_3193577_32 OmpA family K03640 - - 0.000000000000000000000000000000000001613 145.0
HKD1_k127_3193577_33 Methyltransferase type 12 - - - 0.000000000000000000000000000000000002423 149.0
HKD1_k127_3193577_34 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.000000000000000000000000000117 119.0
HKD1_k127_3193577_35 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000001593 127.0
HKD1_k127_3193577_36 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000002257 123.0
HKD1_k127_3193577_37 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000007244 111.0
HKD1_k127_3193577_38 Tetratricopeptide repeat - - - 0.00000000000000000000000002672 116.0
HKD1_k127_3193577_39 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000006052 109.0
HKD1_k127_3193577_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 423.0
HKD1_k127_3193577_40 Domain of unknown function (DUF4340) - - - 0.00000000000000000002768 105.0
HKD1_k127_3193577_41 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000002133 94.0
HKD1_k127_3193577_42 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000005054 94.0
HKD1_k127_3193577_43 Protein of unknown function (DUF2723) - - - 0.000000000000016 88.0
HKD1_k127_3193577_44 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000007631 78.0
HKD1_k127_3193577_46 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000006312 61.0
HKD1_k127_3193577_47 Response regulator receiver domain protein K07667 - - 0.000005196 57.0
HKD1_k127_3193577_48 monooxygenase activity - - - 0.00008037 53.0
HKD1_k127_3193577_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 409.0
HKD1_k127_3193577_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 368.0
HKD1_k127_3193577_7 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 362.0
HKD1_k127_3193577_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 351.0
HKD1_k127_3193577_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 351.0
HKD1_k127_3208600_0 transcriptional regulator, ArsR family protein K03892 - - 0.0000000000000009189 80.0
HKD1_k127_3208600_1 SnoaL-like domain - - - 0.00000005833 64.0
HKD1_k127_3258741_0 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 434.0
HKD1_k127_3258741_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 379.0
HKD1_k127_3258741_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000008907 109.0
HKD1_k127_3264938_0 Carbon starvation protein CstA K06200 - - 1.304e-212 677.0
HKD1_k127_3264938_1 PFAM Aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 494.0
HKD1_k127_3264938_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000004881 235.0
HKD1_k127_3264938_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HKD1_k127_3264938_4 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000008784 147.0
HKD1_k127_3264938_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000001265 137.0
HKD1_k127_3264938_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000000000005939 135.0
HKD1_k127_3264938_7 transcriptional regulator K07726 - - 0.0000000000000000000004137 98.0
HKD1_k127_3264938_8 - - - - 0.0000001724 62.0
HKD1_k127_3269005_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 7e-323 1015.0
HKD1_k127_3269005_1 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.474e-256 818.0
HKD1_k127_3269005_10 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 456.0
HKD1_k127_3269005_11 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 439.0
HKD1_k127_3269005_12 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 428.0
HKD1_k127_3269005_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 428.0
HKD1_k127_3269005_14 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 413.0
HKD1_k127_3269005_15 Transposase and inactivated derivatives K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 401.0
HKD1_k127_3269005_16 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 371.0
HKD1_k127_3269005_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 364.0
HKD1_k127_3269005_18 SMART von Willebrand factor, type A K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 342.0
HKD1_k127_3269005_19 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 332.0
HKD1_k127_3269005_2 Phosphate acyltransferases - - - 3.01e-237 765.0
HKD1_k127_3269005_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 325.0
HKD1_k127_3269005_21 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 320.0
HKD1_k127_3269005_22 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 301.0
HKD1_k127_3269005_23 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004681 289.0
HKD1_k127_3269005_24 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002641 262.0
HKD1_k127_3269005_25 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002935 267.0
HKD1_k127_3269005_26 Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003346 248.0
HKD1_k127_3269005_27 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001311 249.0
HKD1_k127_3269005_28 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000222 242.0
HKD1_k127_3269005_29 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001922 239.0
HKD1_k127_3269005_3 amp-dependent synthetase K01895 - 6.2.1.1 1.639e-212 673.0
HKD1_k127_3269005_30 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001392 253.0
HKD1_k127_3269005_31 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004236 230.0
HKD1_k127_3269005_32 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000008016 226.0
HKD1_k127_3269005_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000002625 229.0
HKD1_k127_3269005_34 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
HKD1_k127_3269005_35 - - - - 0.00000000000000000000000000000000000000000000000000000001057 201.0
HKD1_k127_3269005_36 Wzt C-terminal domain K01990 - - 0.0000000000000000000000000000000000000000000000000000001273 213.0
HKD1_k127_3269005_37 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000003338 199.0
HKD1_k127_3269005_38 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000005799 195.0
HKD1_k127_3269005_39 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000004106 202.0
HKD1_k127_3269005_4 FtsX-like permease family K02004 - - 1.433e-210 685.0
HKD1_k127_3269005_40 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000005526 196.0
HKD1_k127_3269005_41 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000005655 194.0
HKD1_k127_3269005_42 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000004504 181.0
HKD1_k127_3269005_43 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000009083 162.0
HKD1_k127_3269005_44 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000005832 158.0
HKD1_k127_3269005_45 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000004179 145.0
HKD1_k127_3269005_46 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000004204 155.0
HKD1_k127_3269005_47 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000007011 143.0
HKD1_k127_3269005_49 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000001407 143.0
HKD1_k127_3269005_5 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 563.0
HKD1_k127_3269005_50 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.0000000000000000000000000000002824 134.0
HKD1_k127_3269005_51 OsmC-like protein - - - 0.0000000000000000000000000000007414 128.0
HKD1_k127_3269005_52 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000004164 119.0
HKD1_k127_3269005_53 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000008014 113.0
HKD1_k127_3269005_54 4Fe-4S binding domain - - - 0.000000000000000000000003897 115.0
HKD1_k127_3269005_56 Protein of unknown function (DUF1214) - - - 0.00000000000000000000007035 98.0
HKD1_k127_3269005_57 DinB family - - - 0.000000000000000007379 89.0
HKD1_k127_3269005_58 FMN_bind K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000581 85.0
HKD1_k127_3269005_59 - - - - 0.000009668 57.0
HKD1_k127_3269005_6 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 517.0
HKD1_k127_3269005_62 Amidinotransferase K01482 - 3.5.3.18 0.00002439 51.0
HKD1_k127_3269005_63 The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity - - - 0.0007536 51.0
HKD1_k127_3269005_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 496.0
HKD1_k127_3269005_8 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 480.0
HKD1_k127_3269005_9 SMP-30/Gluconolaconase/LRE-like region K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 430.0
HKD1_k127_3345451_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000001008 221.0
HKD1_k127_3345451_1 - - - - 0.0000000000000000003015 91.0
HKD1_k127_3425080_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 519.0
HKD1_k127_3425080_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 431.0
HKD1_k127_3425080_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000001495 237.0
HKD1_k127_3425080_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000003885 216.0
HKD1_k127_3425080_12 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000002711 223.0
HKD1_k127_3425080_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000008957 211.0
HKD1_k127_3425080_14 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000002244 170.0
HKD1_k127_3425080_15 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000002969 134.0
HKD1_k127_3425080_16 Cytochrome C assembly protein - - - 0.00000000000000000000000000002669 127.0
HKD1_k127_3425080_17 von Willebrand factor, type A K07114 - - 0.000000000003624 77.0
HKD1_k127_3425080_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 398.0
HKD1_k127_3425080_3 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 375.0
HKD1_k127_3425080_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 362.0
HKD1_k127_3425080_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 302.0
HKD1_k127_3425080_6 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001803 278.0
HKD1_k127_3425080_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001138 258.0
HKD1_k127_3425080_8 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003793 264.0
HKD1_k127_3425080_9 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
HKD1_k127_34592_0 FAD linked oxidases, C-terminal domain - - - 0.0 1150.0
HKD1_k127_34592_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 8.287e-295 925.0
HKD1_k127_34592_10 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 548.0
HKD1_k127_34592_11 Major facilitator superfamily K08194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 541.0
HKD1_k127_34592_12 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 533.0
HKD1_k127_34592_13 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 524.0
HKD1_k127_34592_14 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 523.0
HKD1_k127_34592_15 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 485.0
HKD1_k127_34592_16 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 485.0
HKD1_k127_34592_17 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 479.0
HKD1_k127_34592_18 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 451.0
HKD1_k127_34592_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 440.0
HKD1_k127_34592_2 WD40-like Beta Propeller Repeat - - - 1.764e-261 818.0
HKD1_k127_34592_20 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 440.0
HKD1_k127_34592_21 Sugar (and other) transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 432.0
HKD1_k127_34592_22 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 428.0
HKD1_k127_34592_23 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 426.0
HKD1_k127_34592_24 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 421.0
HKD1_k127_34592_25 PFAM major facilitator superfamily MFS_1 K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 362.0
HKD1_k127_34592_26 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HKD1_k127_34592_27 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 342.0
HKD1_k127_34592_28 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 317.0
HKD1_k127_34592_29 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 315.0
HKD1_k127_34592_3 DNA topological change K03168 - 5.99.1.2 1.175e-247 788.0
HKD1_k127_34592_30 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 291.0
HKD1_k127_34592_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 289.0
HKD1_k127_34592_32 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007538 272.0
HKD1_k127_34592_33 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000003611 252.0
HKD1_k127_34592_34 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
HKD1_k127_34592_35 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009539 241.0
HKD1_k127_34592_36 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000007198 222.0
HKD1_k127_34592_37 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
HKD1_k127_34592_38 - - - - 0.0000000000000000000000000000000000000000000000000002808 198.0
HKD1_k127_34592_39 - - - - 0.0000000000000000000000000000000000000002138 154.0
HKD1_k127_34592_4 DNA topological change K03168 - 5.99.1.2 2.249e-239 771.0
HKD1_k127_34592_40 - - - - 0.000000000000000000000000000000000000005245 167.0
HKD1_k127_34592_41 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000001912 149.0
HKD1_k127_34592_43 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000001697 130.0
HKD1_k127_34592_44 - - - - 0.000000000000000000000000000191 121.0
HKD1_k127_34592_45 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000001245 124.0
HKD1_k127_34592_46 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000000007581 116.0
HKD1_k127_34592_48 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000245 91.0
HKD1_k127_34592_49 Staphylococcal nuclease homologues - - - 0.000000000000000000896 96.0
HKD1_k127_34592_5 DNA topological change K03168 - 5.99.1.2 1.658e-238 776.0
HKD1_k127_34592_51 Cupin 2, conserved barrel domain protein - - - 0.000000000000388 79.0
HKD1_k127_34592_53 Phosphotriesterase family K07048 - - 0.00000002081 63.0
HKD1_k127_34592_54 - - - - 0.000004427 54.0
HKD1_k127_34592_6 - - - - 1.418e-234 746.0
HKD1_k127_34592_7 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 5.784e-217 682.0
HKD1_k127_34592_8 FAD dependent oxidoreductase - - - 2.024e-207 658.0
HKD1_k127_34592_9 PQQ-like domain - - - 2.429e-197 634.0
HKD1_k127_3556632_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1243.0
HKD1_k127_3556632_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1142.0
HKD1_k127_3556632_10 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.005e-226 708.0
HKD1_k127_3556632_11 - - - - 3.764e-210 677.0
HKD1_k127_3556632_12 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.12e-200 631.0
HKD1_k127_3556632_13 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 621.0
HKD1_k127_3556632_14 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 552.0
HKD1_k127_3556632_15 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 539.0
HKD1_k127_3556632_16 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 540.0
HKD1_k127_3556632_17 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 536.0
HKD1_k127_3556632_18 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 523.0
HKD1_k127_3556632_19 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 516.0
HKD1_k127_3556632_2 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1030.0
HKD1_k127_3556632_20 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 513.0
HKD1_k127_3556632_21 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 496.0
HKD1_k127_3556632_22 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 475.0
HKD1_k127_3556632_23 Pfam:CPSase_L_chain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 467.0
HKD1_k127_3556632_24 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 450.0
HKD1_k127_3556632_25 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 443.0
HKD1_k127_3556632_26 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 438.0
HKD1_k127_3556632_27 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 407.0
HKD1_k127_3556632_28 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 396.0
HKD1_k127_3556632_29 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 376.0
HKD1_k127_3556632_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.981e-292 916.0
HKD1_k127_3556632_30 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 372.0
HKD1_k127_3556632_31 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 377.0
HKD1_k127_3556632_32 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 365.0
HKD1_k127_3556632_33 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 316.0
HKD1_k127_3556632_34 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
HKD1_k127_3556632_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 312.0
HKD1_k127_3556632_36 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 289.0
HKD1_k127_3556632_37 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005961 277.0
HKD1_k127_3556632_38 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000375 281.0
HKD1_k127_3556632_39 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006865 293.0
HKD1_k127_3556632_4 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.365e-266 844.0
HKD1_k127_3556632_40 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004036 263.0
HKD1_k127_3556632_41 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 283.0
HKD1_k127_3556632_42 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005164 262.0
HKD1_k127_3556632_43 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002225 255.0
HKD1_k127_3556632_44 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000006803 241.0
HKD1_k127_3556632_45 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008525 252.0
HKD1_k127_3556632_46 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000973 263.0
HKD1_k127_3556632_47 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000001203 238.0
HKD1_k127_3556632_48 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000001415 233.0
HKD1_k127_3556632_49 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000004142 229.0
HKD1_k127_3556632_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 4.702e-265 839.0
HKD1_k127_3556632_50 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000008247 222.0
HKD1_k127_3556632_51 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000139 213.0
HKD1_k127_3556632_52 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000001614 220.0
HKD1_k127_3556632_53 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000005759 194.0
HKD1_k127_3556632_54 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000139 164.0
HKD1_k127_3556632_55 - - - - 0.000000000000000000000000000000000000001676 153.0
HKD1_k127_3556632_56 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000002148 154.0
HKD1_k127_3556632_57 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000007723 146.0
HKD1_k127_3556632_58 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000009195 149.0
HKD1_k127_3556632_59 YCII-related domain K09780 - - 0.000000000000000000000000000000000004978 138.0
HKD1_k127_3556632_6 DNA topological change K03168 - 5.99.1.2 7.804e-259 822.0
HKD1_k127_3556632_60 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000002522 140.0
HKD1_k127_3556632_61 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000007978 136.0
HKD1_k127_3556632_62 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000004824 130.0
HKD1_k127_3556632_63 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000009406 132.0
HKD1_k127_3556632_64 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002652 124.0
HKD1_k127_3556632_65 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000001648 123.0
HKD1_k127_3556632_66 Cytochrome c - - - 0.00000000000000000000000000002151 128.0
HKD1_k127_3556632_67 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002482 114.0
HKD1_k127_3556632_68 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000005449 112.0
HKD1_k127_3556632_69 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000004297 114.0
HKD1_k127_3556632_7 DNA topological change K03168 - 5.99.1.2 3.138e-256 812.0
HKD1_k127_3556632_70 Biotin-requiring enzyme - - - 0.0000000000000000000008539 105.0
HKD1_k127_3556632_71 response regulator - - - 0.000000000000000000006631 104.0
HKD1_k127_3556632_72 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000002533 93.0
HKD1_k127_3556632_73 OmpA family K03640 - - 0.00000000000000001447 89.0
HKD1_k127_3556632_74 Radical SAM - - - 0.00000000000000001501 96.0
HKD1_k127_3556632_76 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000001885 81.0
HKD1_k127_3556632_77 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000007466 78.0
HKD1_k127_3556632_78 - - - - 0.00000000000004268 77.0
HKD1_k127_3556632_79 PFAM von Willebrand factor type A domain K07114 - - 0.0000000000001708 82.0
HKD1_k127_3556632_8 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.388e-251 784.0
HKD1_k127_3556632_80 lactoylglutathione lyase activity - - - 0.00000000001292 71.0
HKD1_k127_3556632_82 oxidoreductase activity K07114 - - 0.0000000007108 72.0
HKD1_k127_3556632_83 PFAM Abortive infection protein K07052 - - 0.000000002461 68.0
HKD1_k127_3556632_84 TIGRFAM amino acid adenylation domain - - - 0.0000001211 64.0
HKD1_k127_3556632_86 electron transfer activity K08738 - - 0.0001186 54.0
HKD1_k127_3556632_88 Fibronectin type 3 domain - - - 0.0003522 53.0
HKD1_k127_3556632_89 - - - - 0.0003865 49.0
HKD1_k127_3556632_9 DNA topological change K03168 - 5.99.1.2 3.376e-234 749.0
HKD1_k127_3556632_90 - - - - 0.0008502 50.0
HKD1_k127_3588510_0 nucleic acid-templated transcription K18843 - - 0.000000000000000000000000000000000000003371 152.0
HKD1_k127_3588510_1 Dienelactone hydrolase family - - - 0.00000000000000000000000002161 108.0
HKD1_k127_3588510_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.000000000000000000005211 95.0
HKD1_k127_3588510_3 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.0000000000000000007895 88.0
HKD1_k127_3588510_4 PAS domain K07315 - 3.1.3.3 0.00001242 49.0
HKD1_k127_3648362_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 516.0
HKD1_k127_3648362_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000008918 187.0
HKD1_k127_3648362_2 Transposase K07497 - - 0.00000839 48.0
HKD1_k127_3673291_0 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 432.0
HKD1_k127_3673291_1 Aldo/keto reductase family - - - 0.00000000000000000000000001645 118.0
HKD1_k127_3689402_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.66e-307 961.0
HKD1_k127_3689402_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.541e-282 907.0
HKD1_k127_3689402_10 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 509.0
HKD1_k127_3689402_11 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 433.0
HKD1_k127_3689402_12 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 414.0
HKD1_k127_3689402_13 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
HKD1_k127_3689402_14 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 373.0
HKD1_k127_3689402_15 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 376.0
HKD1_k127_3689402_16 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 345.0
HKD1_k127_3689402_17 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 330.0
HKD1_k127_3689402_18 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 324.0
HKD1_k127_3689402_19 Cellulose biosynthesis protein BcsQ K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
HKD1_k127_3689402_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.577e-280 887.0
HKD1_k127_3689402_20 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 304.0
HKD1_k127_3689402_21 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005696 284.0
HKD1_k127_3689402_22 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005408 264.0
HKD1_k127_3689402_23 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
HKD1_k127_3689402_24 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
HKD1_k127_3689402_25 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001365 261.0
HKD1_k127_3689402_26 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000002101 238.0
HKD1_k127_3689402_27 PAS modulated sigma54 specific transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000002826 241.0
HKD1_k127_3689402_28 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
HKD1_k127_3689402_29 type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000001429 208.0
HKD1_k127_3689402_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.945e-256 805.0
HKD1_k127_3689402_30 Type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000001321 201.0
HKD1_k127_3689402_31 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000002733 194.0
HKD1_k127_3689402_32 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000001921 175.0
HKD1_k127_3689402_33 Gaf domain - - - 0.00000000000000000000000000000000000000005532 169.0
HKD1_k127_3689402_34 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000006786 162.0
HKD1_k127_3689402_35 antitermination protein NusG K05785 - - 0.00000000000000000000000000000002829 137.0
HKD1_k127_3689402_36 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000004466 126.0
HKD1_k127_3689402_37 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000000000000000000000002365 126.0
HKD1_k127_3689402_38 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000007515 130.0
HKD1_k127_3689402_39 AAA domain K02282 - - 0.0000000000000000000000000006877 126.0
HKD1_k127_3689402_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.323e-238 745.0
HKD1_k127_3689402_40 PFAM von Willebrand factor type A - - - 0.000000000000000000000000002289 129.0
HKD1_k127_3689402_41 DinB family - - - 0.000000000000000000000000006509 116.0
HKD1_k127_3689402_42 PAP2 superfamily - - - 0.000000000000000000000006692 113.0
HKD1_k127_3689402_43 glycosyl transferase family 2 K11936 - - 0.000000000000000000000006896 117.0
HKD1_k127_3689402_44 Regulatory protein, FmdB - - - 0.00000000000000000000001558 104.0
HKD1_k127_3689402_45 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000311 101.0
HKD1_k127_3689402_46 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000005193 112.0
HKD1_k127_3689402_47 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000009046 103.0
HKD1_k127_3689402_48 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000002656 101.0
HKD1_k127_3689402_49 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000004394 99.0
HKD1_k127_3689402_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.154e-228 713.0
HKD1_k127_3689402_50 R3H domain protein K06346 - - 0.000000000000000002326 92.0
HKD1_k127_3689402_51 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000004255 78.0
HKD1_k127_3689402_52 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000005288 72.0
HKD1_k127_3689402_53 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000774 84.0
HKD1_k127_3689402_54 Tetratricopeptide repeat - - - 0.0000000000003956 78.0
HKD1_k127_3689402_55 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000009922 73.0
HKD1_k127_3689402_57 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000002463 71.0
HKD1_k127_3689402_58 TadE-like protein - - - 0.0000000005682 70.0
HKD1_k127_3689402_59 Domain of unknown function (DUF4382) - - - 0.0000001441 60.0
HKD1_k127_3689402_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 618.0
HKD1_k127_3689402_60 lyase activity - - - 0.0000002548 64.0
HKD1_k127_3689402_61 Flp Fap pilin component - - - 0.0000003934 57.0
HKD1_k127_3689402_62 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.0000004797 61.0
HKD1_k127_3689402_63 HlyD family secretion protein K19291 - 2.4.1.33 0.000005261 53.0
HKD1_k127_3689402_64 Prenyltransferase K13277 - - 0.00008725 54.0
HKD1_k127_3689402_65 PFAM Flp Fap pilin component K02651 - - 0.00009303 49.0
HKD1_k127_3689402_66 Flp/Fap pilin component K02651 - - 0.0002586 47.0
HKD1_k127_3689402_67 Flp/Fap pilin component K02651 - - 0.0007961 48.0
HKD1_k127_3689402_7 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 616.0
HKD1_k127_3689402_8 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 529.0
HKD1_k127_3689402_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 503.0
HKD1_k127_3743619_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 594.0
HKD1_k127_3743619_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 499.0
HKD1_k127_3743619_10 - - - - 0.000000000000000000000000000000000000000000000000000002899 197.0
HKD1_k127_3743619_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000001248 147.0
HKD1_k127_3743619_12 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.0000000000000000000000000000000002838 143.0
HKD1_k127_3743619_13 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000001439 121.0
HKD1_k127_3743619_14 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000006592 119.0
HKD1_k127_3743619_15 Ammonium transporter K03320 - - 0.0000000000000000000001689 97.0
HKD1_k127_3743619_16 AAA ATPase domain - - - 0.000000000000001564 89.0
HKD1_k127_3743619_17 cell cycle K05589,K12065,K13052 - - 0.000008218 53.0
HKD1_k127_3743619_2 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 480.0
HKD1_k127_3743619_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 455.0
HKD1_k127_3743619_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 452.0
HKD1_k127_3743619_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 336.0
HKD1_k127_3743619_6 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005998 285.0
HKD1_k127_3743619_7 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000001374 234.0
HKD1_k127_3743619_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000337 212.0
HKD1_k127_3743619_9 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000002805 218.0
HKD1_k127_3800405_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 580.0
HKD1_k127_3800405_1 ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 491.0
HKD1_k127_3800405_2 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 428.0
HKD1_k127_3800405_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000004905 248.0
HKD1_k127_3800405_4 - - - - 0.00000000000000000000000000000000000000000000000000000000004563 219.0
HKD1_k127_3800405_5 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000006075 177.0
HKD1_k127_3828630_0 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00009244 50.0
HKD1_k127_3924079_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1242.0
HKD1_k127_3924079_1 Cytochrome c554 and c-prime - - - 1.725e-299 947.0
HKD1_k127_3924079_10 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 2.027e-195 632.0
HKD1_k127_3924079_11 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 580.0
HKD1_k127_3924079_12 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 524.0
HKD1_k127_3924079_13 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 554.0
HKD1_k127_3924079_14 Glucose-6-phosphate dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 511.0
HKD1_k127_3924079_15 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 503.0
HKD1_k127_3924079_16 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 471.0
HKD1_k127_3924079_17 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 452.0
HKD1_k127_3924079_18 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 427.0
HKD1_k127_3924079_19 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 421.0
HKD1_k127_3924079_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 7.578e-295 918.0
HKD1_k127_3924079_20 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 425.0
HKD1_k127_3924079_21 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 389.0
HKD1_k127_3924079_22 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 392.0
HKD1_k127_3924079_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 367.0
HKD1_k127_3924079_24 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
HKD1_k127_3924079_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 336.0
HKD1_k127_3924079_26 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 288.0
HKD1_k127_3924079_27 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003593 273.0
HKD1_k127_3924079_28 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000003204 255.0
HKD1_k127_3924079_29 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001746 254.0
HKD1_k127_3924079_3 Dehydrogenase K00117 - 1.1.5.2 4.81e-280 877.0
HKD1_k127_3924079_30 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002395 242.0
HKD1_k127_3924079_31 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006101 259.0
HKD1_k127_3924079_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001457 246.0
HKD1_k127_3924079_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000003476 227.0
HKD1_k127_3924079_34 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000008041 231.0
HKD1_k127_3924079_35 - - - - 0.0000000000000000000000000000000000000000000000000000001006 198.0
HKD1_k127_3924079_36 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000001656 203.0
HKD1_k127_3924079_37 - - - - 0.000000000000000000000000000000000000000000000000855 187.0
HKD1_k127_3924079_38 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000003738 167.0
HKD1_k127_3924079_39 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000004299 164.0
HKD1_k127_3924079_4 DNA topological change - - - 2.169e-263 833.0
HKD1_k127_3924079_40 spectrin binding K15502,K19947 - 1.14.13.225 0.000000000000000000000000000000000007159 155.0
HKD1_k127_3924079_41 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000003759 141.0
HKD1_k127_3924079_42 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000005972 136.0
HKD1_k127_3924079_43 TonB-dependent receptor - - - 0.00000000000000000000000001021 127.0
HKD1_k127_3924079_44 membrane - - - 0.000000000000000000000002296 113.0
HKD1_k127_3924079_45 membrane - - - 0.00000000000000000000005745 111.0
HKD1_k127_3924079_46 Membrane - - - 0.0000000000000001372 89.0
HKD1_k127_3924079_47 - - - - 0.0000000000000001447 87.0
HKD1_k127_3924079_49 oxidoreductase activity - - - 0.000000008976 69.0
HKD1_k127_3924079_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.1e-263 823.0
HKD1_k127_3924079_50 Lipocalin-like domain - - - 0.00001899 56.0
HKD1_k127_3924079_51 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00003519 53.0
HKD1_k127_3924079_52 Polyketide cyclase / dehydrase and lipid transport - - - 0.00004116 48.0
HKD1_k127_3924079_53 Cupin 2, conserved barrel domain protein - - - 0.0000517 55.0
HKD1_k127_3924079_6 DNA topological change K03168 - 5.99.1.2 2.513e-238 761.0
HKD1_k127_3924079_7 DNA topological change K03168 - 5.99.1.2 2.124e-232 745.0
HKD1_k127_3924079_8 ASPIC and UnbV - - - 1.529e-213 682.0
HKD1_k127_3924079_9 radical SAM domain protein - - - 2.278e-202 642.0
HKD1_k127_4065236_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1065.0
HKD1_k127_4065236_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 407.0
HKD1_k127_4065236_10 Belongs to the 'phage' integrase family K14059 - - 0.000000000004189 71.0
HKD1_k127_4065236_2 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 406.0
HKD1_k127_4065236_3 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 359.0
HKD1_k127_4065236_4 - - - - 0.00000000000000000000000000000000000000000000000001775 197.0
HKD1_k127_4065236_5 Mechanosensitive Ion channel - - - 0.000000000000000000000000000000000000001175 153.0
HKD1_k127_4065236_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000005412 108.0
HKD1_k127_4065236_7 - - - - 0.000000000000000002571 97.0
HKD1_k127_4065236_8 Belongs to the 'phage' integrase family - - - 0.00000000000002181 77.0
HKD1_k127_4065236_9 Belongs to the 'phage' integrase family - - - 0.0000000000003344 72.0
HKD1_k127_4070941_0 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
HKD1_k127_4070941_1 Uncharacterized protein family (UPF0051) K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 355.0
HKD1_k127_4070941_2 iron-sulfur cluster assembly K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 369.0
HKD1_k127_4070941_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000002366 114.0
HKD1_k127_4103746_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 355.0
HKD1_k127_4103746_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000004493 88.0
HKD1_k127_4103749_0 DNA topological change K03168 - 5.99.1.2 5.361e-207 672.0
HKD1_k127_4103749_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 450.0
HKD1_k127_4103749_10 PFAM PKD domain containing protein - - - 0.0000002977 62.0
HKD1_k127_4103749_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 363.0
HKD1_k127_4103749_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 368.0
HKD1_k127_4103749_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006602 280.0
HKD1_k127_4103749_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000002222 226.0
HKD1_k127_4103749_6 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000002026 153.0
HKD1_k127_4103749_7 Acetyltransferase (GNAT) domain - - - 0.000000000068 71.0
HKD1_k127_4103749_8 COG4308 Limonene-1,2-epoxide hydrolase K10533 - 3.3.2.8 0.0000000107 62.0
HKD1_k127_4103749_9 - - - - 0.000000146 55.0
HKD1_k127_419574_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 5.097e-253 794.0
HKD1_k127_419574_1 Amidase K01426 - 3.5.1.4 6.844e-217 694.0
HKD1_k127_419574_10 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 380.0
HKD1_k127_419574_11 response regulator receiver K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 381.0
HKD1_k127_419574_12 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 363.0
HKD1_k127_419574_13 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 351.0
HKD1_k127_419574_14 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
HKD1_k127_419574_15 HMGL-like K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 333.0
HKD1_k127_419574_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 336.0
HKD1_k127_419574_17 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 333.0
HKD1_k127_419574_18 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 321.0
HKD1_k127_419574_19 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 315.0
HKD1_k127_419574_2 Protein of unknown function, DUF255 K06888 - - 6.661e-215 689.0
HKD1_k127_419574_20 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 325.0
HKD1_k127_419574_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
HKD1_k127_419574_22 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 307.0
HKD1_k127_419574_23 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 301.0
HKD1_k127_419574_24 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001119 298.0
HKD1_k127_419574_25 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000424 281.0
HKD1_k127_419574_26 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001023 273.0
HKD1_k127_419574_27 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000005629 252.0
HKD1_k127_419574_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001452 265.0
HKD1_k127_419574_29 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006219 251.0
HKD1_k127_419574_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.08e-198 640.0
HKD1_k127_419574_30 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000005103 236.0
HKD1_k127_419574_31 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
HKD1_k127_419574_32 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000004535 237.0
HKD1_k127_419574_33 Cytochrome c K03611 - - 0.0000000000000000000000000000000000000000000000000000009523 204.0
HKD1_k127_419574_34 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000003833 197.0
HKD1_k127_419574_35 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000001499 194.0
HKD1_k127_419574_36 - - - - 0.0000000000000000000000000000000000000000000000001233 180.0
HKD1_k127_419574_37 intracellular protease K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000005613 178.0
HKD1_k127_419574_38 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000004057 177.0
HKD1_k127_419574_39 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000004996 165.0
HKD1_k127_419574_4 Dehydrogenase K00117 - 1.1.5.2 2.976e-198 638.0
HKD1_k127_419574_40 DinB family - - - 0.000000000000000000000000000000000000000001609 162.0
HKD1_k127_419574_41 Trehalose utilisation - - - 0.000000000000000000000000000000000000008081 160.0
HKD1_k127_419574_42 DinB family - - - 0.0000000000000000000000000000000000006022 145.0
HKD1_k127_419574_43 - - - - 0.000000000000000000000000000000003519 141.0
HKD1_k127_419574_44 beta-galactosidase activity - - - 0.00000000000000000000000000000007296 139.0
HKD1_k127_419574_45 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000005129 131.0
HKD1_k127_419574_46 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000003396 119.0
HKD1_k127_419574_47 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.0000000000000000000000000004672 124.0
HKD1_k127_419574_49 Periplasmic or secreted lipoprotein - - - 0.000000000000000000693 96.0
HKD1_k127_419574_5 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 582.0
HKD1_k127_419574_50 Belongs to the UPF0761 family K07058 - - 0.0000000000000000007469 101.0
HKD1_k127_419574_52 Biotin carboxylase, N-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.0000000000000007044 86.0
HKD1_k127_419574_53 SnoaL-like domain - - - 0.0000000000000008323 83.0
HKD1_k127_419574_54 Protein of unknown function (DUF2911) - - - 0.000000000000004294 84.0
HKD1_k127_419574_55 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000002301 72.0
HKD1_k127_419574_56 SnoaL-like domain - - - 0.000000000002394 76.0
HKD1_k127_419574_57 Redoxin K03564 - 1.11.1.15 0.000000001384 69.0
HKD1_k127_419574_58 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.000000008183 68.0
HKD1_k127_419574_6 CoA carboxylase activity K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 526.0
HKD1_k127_419574_60 4Fe-4S binding domain K03616 - - 0.0000004113 61.0
HKD1_k127_419574_62 Pfam:N_methyl_2 - - - 0.0000009629 57.0
HKD1_k127_419574_63 - K07401 - - 0.00001579 49.0
HKD1_k127_419574_64 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00006463 54.0
HKD1_k127_419574_65 PFAM Flp Fap pilin component K02651 - - 0.0005298 45.0
HKD1_k127_419574_7 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 529.0
HKD1_k127_419574_8 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 474.0
HKD1_k127_419574_9 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 443.0
HKD1_k127_4240727_0 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system K02526 GO:0003674,GO:0005215,GO:0005342,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015649,GO:0015672,GO:0015711,GO:0015718,GO:0015749,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044464,GO:0046411,GO:0046942,GO:0046943,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 320.0
HKD1_k127_4240727_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000001941 206.0
HKD1_k127_4240727_2 OsmC-like protein K07397 - - 0.0000000000000000000000000001447 119.0
HKD1_k127_4260028_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.697e-229 722.0
HKD1_k127_4260028_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 464.0
HKD1_k127_4260028_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000002506 196.0
HKD1_k127_4260028_11 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000002726 193.0
HKD1_k127_4260028_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000009262 182.0
HKD1_k127_4260028_13 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000009868 189.0
HKD1_k127_4260028_14 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000008062 184.0
HKD1_k127_4260028_15 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 - 3.4.25.1 0.0000000000000000000000000000004545 134.0
HKD1_k127_4260028_16 Bacterial-like globin K06886 - - 0.00000000000000000000000000008884 120.0
HKD1_k127_4260028_17 Phospholipid methyltransferase - - - 0.000000000000000006879 91.0
HKD1_k127_4260028_18 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000001313 78.0
HKD1_k127_4260028_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 460.0
HKD1_k127_4260028_20 - - - - 0.0001185 53.0
HKD1_k127_4260028_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 329.0
HKD1_k127_4260028_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 293.0
HKD1_k127_4260028_5 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009944 263.0
HKD1_k127_4260028_6 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000009979 268.0
HKD1_k127_4260028_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002055 248.0
HKD1_k127_4260028_8 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.000000000000000000000000000000000000000000000000000000000006224 220.0
HKD1_k127_4260028_9 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000004211 211.0
HKD1_k127_4268646_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 325.0
HKD1_k127_4268646_1 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007347 276.0
HKD1_k127_4268646_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000005273 187.0
HKD1_k127_4268646_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000001826 98.0
HKD1_k127_4295376_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001414 242.0
HKD1_k127_4295376_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000001481 137.0
HKD1_k127_4295376_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000004691 72.0
HKD1_k127_4318341_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1065.0
HKD1_k127_4318341_1 nodulation K00612 - - 7.376e-257 805.0
HKD1_k127_4318341_10 PFAM Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 315.0
HKD1_k127_4318341_11 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 291.0
HKD1_k127_4318341_12 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001542 274.0
HKD1_k127_4318341_13 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008049 265.0
HKD1_k127_4318341_14 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
HKD1_k127_4318341_15 O-acyltransferase activity K00633 - 2.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000574 225.0
HKD1_k127_4318341_16 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000005806 235.0
HKD1_k127_4318341_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000245 221.0
HKD1_k127_4318341_18 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000002449 212.0
HKD1_k127_4318341_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000002741 214.0
HKD1_k127_4318341_2 Cytochrome c-type biogenesis protein K02198 - - 4.127e-232 744.0
HKD1_k127_4318341_20 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000001415 189.0
HKD1_k127_4318341_21 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000001433 190.0
HKD1_k127_4318341_22 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000007929 175.0
HKD1_k127_4318341_23 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000006658 163.0
HKD1_k127_4318341_24 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000001773 167.0
HKD1_k127_4318341_25 oligosaccharyl transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000000000001403 159.0
HKD1_k127_4318341_26 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000005538 153.0
HKD1_k127_4318341_27 slime layer polysaccharide biosynthetic process K06871,K16710 - - 0.000000000000000000000000000000000007857 151.0
HKD1_k127_4318341_28 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000003571 149.0
HKD1_k127_4318341_29 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000001008 138.0
HKD1_k127_4318341_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 514.0
HKD1_k127_4318341_30 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000004305 128.0
HKD1_k127_4318341_31 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000006028 134.0
HKD1_k127_4318341_32 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000007112 136.0
HKD1_k127_4318341_33 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000001296 119.0
HKD1_k127_4318341_34 Methyltransferase domain - - - 0.000000000000000000000000004772 120.0
HKD1_k127_4318341_35 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000001414 113.0
HKD1_k127_4318341_36 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000004792 98.0
HKD1_k127_4318341_37 6-phosphogluconolactonase activity - - - 0.0000000000000001127 93.0
HKD1_k127_4318341_38 2Fe-2S -binding - - - 0.0000000000000001572 79.0
HKD1_k127_4318341_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 461.0
HKD1_k127_4318341_40 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000002002 82.0
HKD1_k127_4318341_41 - - - - 0.0000000000003516 80.0
HKD1_k127_4318341_42 - - - - 0.00000000000861 66.0
HKD1_k127_4318341_43 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000001007 72.0
HKD1_k127_4318341_44 - - - - 0.00000002049 61.0
HKD1_k127_4318341_45 - - - - 0.00003401 48.0
HKD1_k127_4318341_46 membrane - - - 0.00007747 56.0
HKD1_k127_4318341_48 domain protein - - - 0.0002611 53.0
HKD1_k127_4318341_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 382.0
HKD1_k127_4318341_6 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 361.0
HKD1_k127_4318341_7 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 335.0
HKD1_k127_4318341_8 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 341.0
HKD1_k127_4318341_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 334.0
HKD1_k127_4319032_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2111.0
HKD1_k127_4319032_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1374.0
HKD1_k127_4319032_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001535 233.0
HKD1_k127_4319032_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000001279 204.0
HKD1_k127_4319032_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000211 154.0
HKD1_k127_4319032_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000009257 115.0
HKD1_k127_4319032_6 - - - - 0.0000000000000000000004804 100.0
HKD1_k127_4319032_7 - - - - 0.0000000000000000003271 95.0
HKD1_k127_4369685_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.582e-283 881.0
HKD1_k127_4369685_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.512e-214 679.0
HKD1_k127_4369685_10 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 439.0
HKD1_k127_4369685_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 413.0
HKD1_k127_4369685_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 412.0
HKD1_k127_4369685_13 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 373.0
HKD1_k127_4369685_14 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 342.0
HKD1_k127_4369685_15 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 320.0
HKD1_k127_4369685_16 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
HKD1_k127_4369685_17 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 312.0
HKD1_k127_4369685_18 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007787 279.0
HKD1_k127_4369685_19 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000008843 272.0
HKD1_k127_4369685_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 599.0
HKD1_k127_4369685_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000005853 235.0
HKD1_k127_4369685_21 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000001143 222.0
HKD1_k127_4369685_22 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000001211 163.0
HKD1_k127_4369685_23 Reverse transcriptase-like K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000000007023 139.0
HKD1_k127_4369685_24 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000002069 138.0
HKD1_k127_4369685_25 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000005956 130.0
HKD1_k127_4369685_26 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000004299 109.0
HKD1_k127_4369685_27 Helicase K03722 - 3.6.4.12 0.000000000000000000004043 94.0
HKD1_k127_4369685_28 DivIVA protein K04074 - - 0.0000000000000004829 88.0
HKD1_k127_4369685_29 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000004067 81.0
HKD1_k127_4369685_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 557.0
HKD1_k127_4369685_30 peptidyl-tyrosine sulfation - - - 0.00003577 55.0
HKD1_k127_4369685_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0002773 49.0
HKD1_k127_4369685_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 514.0
HKD1_k127_4369685_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 470.0
HKD1_k127_4369685_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 442.0
HKD1_k127_4369685_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 450.0
HKD1_k127_4369685_8 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 435.0
HKD1_k127_4369685_9 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 439.0
HKD1_k127_4380738_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1203.0
HKD1_k127_4380738_1 AMP-binding enzyme C-terminal domain K00666 - - 2.629e-256 801.0
HKD1_k127_4380738_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 421.0
HKD1_k127_4380738_11 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 413.0
HKD1_k127_4380738_12 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 394.0
HKD1_k127_4380738_13 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 372.0
HKD1_k127_4380738_14 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 385.0
HKD1_k127_4380738_15 Steryl acetyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 369.0
HKD1_k127_4380738_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 354.0
HKD1_k127_4380738_17 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 349.0
HKD1_k127_4380738_18 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 346.0
HKD1_k127_4380738_19 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
HKD1_k127_4380738_2 AAA domain - - - 7.999e-255 810.0
HKD1_k127_4380738_20 Acetohydroxy acid isomeroreductase, NADPH-binding domain K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 323.0
HKD1_k127_4380738_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 348.0
HKD1_k127_4380738_22 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 320.0
HKD1_k127_4380738_23 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 315.0
HKD1_k127_4380738_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 304.0
HKD1_k127_4380738_25 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
HKD1_k127_4380738_26 NADH:flavin oxidoreductase / NADH oxidase family K00317,K21833 - 1.5.8.1,1.5.8.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HKD1_k127_4380738_27 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009331 281.0
HKD1_k127_4380738_28 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005284 277.0
HKD1_k127_4380738_29 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
HKD1_k127_4380738_3 Amino acid permease - - - 1.886e-249 792.0
HKD1_k127_4380738_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002692 258.0
HKD1_k127_4380738_31 Histidine kinase K07644,K18351 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001745 261.0
HKD1_k127_4380738_32 COG3911 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005566 246.0
HKD1_k127_4380738_33 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 248.0
HKD1_k127_4380738_34 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000001377 233.0
HKD1_k127_4380738_35 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000023 242.0
HKD1_k127_4380738_36 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000001478 220.0
HKD1_k127_4380738_37 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000003199 228.0
HKD1_k127_4380738_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000007017 224.0
HKD1_k127_4380738_39 Transcriptional regulator K07669 - - 0.000000000000000000000000000000000000000000000000000000000005289 214.0
HKD1_k127_4380738_4 AMP-binding enzyme C-terminal domain K00666 - - 1.338e-204 651.0
HKD1_k127_4380738_40 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000001027 216.0
HKD1_k127_4380738_41 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000002089 214.0
HKD1_k127_4380738_42 - - - - 0.0000000000000000000000000000000000000000000000000000007641 208.0
HKD1_k127_4380738_43 - - - - 0.0000000000000000000000000000000000000000000000000000007673 205.0
HKD1_k127_4380738_44 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000001883 195.0
HKD1_k127_4380738_45 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000003227 193.0
HKD1_k127_4380738_46 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000004822 191.0
HKD1_k127_4380738_48 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002116 153.0
HKD1_k127_4380738_49 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000001062 152.0
HKD1_k127_4380738_5 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K02433 - 6.3.5.6,6.3.5.7 6.666e-202 646.0
HKD1_k127_4380738_50 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000006135 147.0
HKD1_k127_4380738_51 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000362 141.0
HKD1_k127_4380738_52 - - - - 0.00000000000000000000000000000003071 131.0
HKD1_k127_4380738_53 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000002018 114.0
HKD1_k127_4380738_54 metallopeptidase activity - - - 0.00000000000000000003887 106.0
HKD1_k127_4380738_55 Carboxypeptidase regulatory-like domain K18235 - - 0.00000000000000000004204 106.0
HKD1_k127_4380738_56 - - - - 0.00000000000000004342 87.0
HKD1_k127_4380738_57 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000744 85.0
HKD1_k127_4380738_58 - - - - 0.00000000000000008534 93.0
HKD1_k127_4380738_59 NADH-dependent flavin oxidoreductase - - - 0.0000000000000007912 82.0
HKD1_k127_4380738_6 Sodium:solute symporter family K14393 - - 2.062e-196 631.0
HKD1_k127_4380738_60 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000008715 76.0
HKD1_k127_4380738_62 - - - - 0.00000000000103 78.0
HKD1_k127_4380738_63 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000002309 79.0
HKD1_k127_4380738_64 Protein of unknown function, DUF485 - - - 0.000000000002469 73.0
HKD1_k127_4380738_65 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000549 73.0
HKD1_k127_4380738_66 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000008819 65.0
HKD1_k127_4380738_67 - - - - 0.0000000318 64.0
HKD1_k127_4380738_68 Peptidase s1 and s6 chymotrypsin hap - - - 0.000000203 64.0
HKD1_k127_4380738_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.418e-194 616.0
HKD1_k127_4380738_8 Pyrrolo-quinoline quinone - - - 3.019e-194 625.0
HKD1_k127_4380738_9 aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 460.0
HKD1_k127_4486374_0 - - - - 0.000000000000000000000000000000000000000000000000000000002086 205.0
HKD1_k127_4486374_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000402 151.0
HKD1_k127_4486374_2 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01708 - 4.2.1.42 0.0000000000000000000000000001199 115.0
HKD1_k127_4514898_0 Methionine synthase K00548 - 2.1.1.13 0.0 1685.0
HKD1_k127_4514898_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1151.0
HKD1_k127_4514898_10 glutamine synthetase K01915 - 6.3.1.2 2.328e-223 700.0
HKD1_k127_4514898_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 638.0
HKD1_k127_4514898_12 transmembrane transporter activity K08196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 585.0
HKD1_k127_4514898_13 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 522.0
HKD1_k127_4514898_14 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 511.0
HKD1_k127_4514898_15 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 475.0
HKD1_k127_4514898_16 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
HKD1_k127_4514898_17 ABC-type multidrug transport system ATPase and permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 468.0
HKD1_k127_4514898_18 PFAM Glycosyl transferase, group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 434.0
HKD1_k127_4514898_19 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 422.0
HKD1_k127_4514898_2 Peptidase M14, carboxypeptidase A - - - 5e-324 1013.0
HKD1_k127_4514898_20 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 407.0
HKD1_k127_4514898_21 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 392.0
HKD1_k127_4514898_22 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 346.0
HKD1_k127_4514898_23 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 351.0
HKD1_k127_4514898_24 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 317.0
HKD1_k127_4514898_25 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 304.0
HKD1_k127_4514898_26 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 297.0
HKD1_k127_4514898_27 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 287.0
HKD1_k127_4514898_28 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
HKD1_k127_4514898_29 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008049 294.0
HKD1_k127_4514898_3 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 1.401e-294 924.0
HKD1_k127_4514898_30 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006559 287.0
HKD1_k127_4514898_31 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
HKD1_k127_4514898_32 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006386 277.0
HKD1_k127_4514898_33 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001691 242.0
HKD1_k127_4514898_34 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003619 248.0
HKD1_k127_4514898_35 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000004764 233.0
HKD1_k127_4514898_36 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
HKD1_k127_4514898_37 - K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000686 233.0
HKD1_k127_4514898_38 deacetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000009765 229.0
HKD1_k127_4514898_39 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000004406 224.0
HKD1_k127_4514898_4 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 3.111e-275 859.0
HKD1_k127_4514898_40 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000001661 217.0
HKD1_k127_4514898_41 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000001182 228.0
HKD1_k127_4514898_42 - - - - 0.000000000000000000000000000000000000000000000000000005755 202.0
HKD1_k127_4514898_43 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000677 189.0
HKD1_k127_4514898_44 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001234 202.0
HKD1_k127_4514898_45 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000001774 198.0
HKD1_k127_4514898_46 - - - - 0.00000000000000000000000000000000000000000000001104 186.0
HKD1_k127_4514898_47 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000004954 177.0
HKD1_k127_4514898_48 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000006456 155.0
HKD1_k127_4514898_49 Amino acid oxidase - - - 0.000000000000000000000000000000000008602 151.0
HKD1_k127_4514898_5 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.484e-262 821.0
HKD1_k127_4514898_50 NUDIX domain - - - 0.00000000000000000000000000000000001881 147.0
HKD1_k127_4514898_51 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000001426 150.0
HKD1_k127_4514898_52 GDSL-like lipase acylhydrolase domain protein - - - 0.000000000000000000000000000003962 131.0
HKD1_k127_4514898_53 DTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000962 125.0
HKD1_k127_4514898_54 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000000000000000004612 122.0
HKD1_k127_4514898_55 AAA domain - - - 0.0000000000000000000000002181 112.0
HKD1_k127_4514898_56 Methyltransferase domain - - - 0.0000000000000000000003359 111.0
HKD1_k127_4514898_57 Domain of unknown function (DUF1772) - - - 0.00000000000000001026 91.0
HKD1_k127_4514898_58 NIPSNAP - - - 0.000000000000001014 83.0
HKD1_k127_4514898_59 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000005177 69.0
HKD1_k127_4514898_6 PFAM LmbE family protein K22136 - - 5.497e-250 804.0
HKD1_k127_4514898_60 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000002897 59.0
HKD1_k127_4514898_61 Histidine kinase - - - 0.0000003937 60.0
HKD1_k127_4514898_62 FR47-like protein - - - 0.0000004915 61.0
HKD1_k127_4514898_63 zinc ion binding - - - 0.0000004928 59.0
HKD1_k127_4514898_64 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000008507 59.0
HKD1_k127_4514898_7 DNA topological change K03168 - 5.99.1.2 9.104e-239 763.0
HKD1_k127_4514898_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.312e-237 744.0
HKD1_k127_4514898_9 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 2.931e-233 734.0
HKD1_k127_4593910_0 - - - - 0.0 1130.0
HKD1_k127_4593910_1 Dehydrogenase K00117 - 1.1.5.2 2.05e-291 910.0
HKD1_k127_4593910_10 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 611.0
HKD1_k127_4593910_100 - - - - 0.000000000001548 76.0
HKD1_k127_4593910_101 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000003243 77.0
HKD1_k127_4593910_102 Calcineurin-like phosphoesterase - - - 0.00000000001769 77.0
HKD1_k127_4593910_103 Cupin 2, conserved barrel domain protein - - - 0.0000000001903 71.0
HKD1_k127_4593910_104 Haem-degrading - - - 0.0000000002685 68.0
HKD1_k127_4593910_105 Cytochrome c - - - 0.000000008847 63.0
HKD1_k127_4593910_106 Glycosyltransferase family 87 - - - 0.00000001831 66.0
HKD1_k127_4593910_107 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 0.00000003242 60.0
HKD1_k127_4593910_108 Domain of unknown function (DUF4390) - - - 0.0000001774 62.0
HKD1_k127_4593910_109 Haem-degrading - - - 0.000001155 57.0
HKD1_k127_4593910_11 membrane organization K07277,K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 651.0
HKD1_k127_4593910_110 thiolester hydrolase activity K00627,K06889 - 2.3.1.12 0.000001196 59.0
HKD1_k127_4593910_111 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000002119 59.0
HKD1_k127_4593910_112 Glyoxalase-like domain K01759 - 4.4.1.5 0.000002811 59.0
HKD1_k127_4593910_113 Periplasmic copper-binding protein (NosD) K07218 - - 0.000006256 59.0
HKD1_k127_4593910_115 - - - - 0.0001933 51.0
HKD1_k127_4593910_116 Tetratricopeptide repeat - - - 0.0006945 49.0
HKD1_k127_4593910_12 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 577.0
HKD1_k127_4593910_13 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 552.0
HKD1_k127_4593910_14 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 535.0
HKD1_k127_4593910_15 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 542.0
HKD1_k127_4593910_16 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 522.0
HKD1_k127_4593910_17 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 518.0
HKD1_k127_4593910_18 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 460.0
HKD1_k127_4593910_19 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 443.0
HKD1_k127_4593910_2 Peptidase S46 - - - 1.248e-273 857.0
HKD1_k127_4593910_20 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 439.0
HKD1_k127_4593910_21 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 434.0
HKD1_k127_4593910_22 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 434.0
HKD1_k127_4593910_23 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 433.0
HKD1_k127_4593910_24 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 454.0
HKD1_k127_4593910_25 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 425.0
HKD1_k127_4593910_26 Alpha beta hydrolase K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 424.0
HKD1_k127_4593910_27 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 416.0
HKD1_k127_4593910_28 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 416.0
HKD1_k127_4593910_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 411.0
HKD1_k127_4593910_3 PQQ-like domain K00114 - 1.1.2.8 4.268e-270 853.0
HKD1_k127_4593910_30 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 394.0
HKD1_k127_4593910_31 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 396.0
HKD1_k127_4593910_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 393.0
HKD1_k127_4593910_33 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 388.0
HKD1_k127_4593910_34 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 381.0
HKD1_k127_4593910_35 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 398.0
HKD1_k127_4593910_36 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 385.0
HKD1_k127_4593910_37 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 380.0
HKD1_k127_4593910_38 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 390.0
HKD1_k127_4593910_39 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 360.0
HKD1_k127_4593910_4 Dehydrogenase K00117 - 1.1.5.2 4.174e-267 847.0
HKD1_k127_4593910_40 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 353.0
HKD1_k127_4593910_41 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 362.0
HKD1_k127_4593910_42 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 354.0
HKD1_k127_4593910_43 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 349.0
HKD1_k127_4593910_44 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 353.0
HKD1_k127_4593910_45 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 348.0
HKD1_k127_4593910_46 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 341.0
HKD1_k127_4593910_47 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 327.0
HKD1_k127_4593910_48 2OG-Fe dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 319.0
HKD1_k127_4593910_49 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 327.0
HKD1_k127_4593910_5 membrane K07027,K14205 - 2.3.2.3 1.355e-258 822.0
HKD1_k127_4593910_50 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 320.0
HKD1_k127_4593910_51 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
HKD1_k127_4593910_52 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 318.0
HKD1_k127_4593910_53 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 310.0
HKD1_k127_4593910_54 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 300.0
HKD1_k127_4593910_55 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 308.0
HKD1_k127_4593910_56 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007613 290.0
HKD1_k127_4593910_57 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003648 283.0
HKD1_k127_4593910_58 PFAM GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
HKD1_k127_4593910_59 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001887 270.0
HKD1_k127_4593910_6 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 1.463e-240 749.0
HKD1_k127_4593910_60 abc transporter atp-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
HKD1_k127_4593910_61 regulation of response to stimulus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002067 267.0
HKD1_k127_4593910_62 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
HKD1_k127_4593910_63 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004012 241.0
HKD1_k127_4593910_64 - - - - 0.00000000000000000000000000000000000000000000000000000000004802 217.0
HKD1_k127_4593910_65 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000003187 215.0
HKD1_k127_4593910_66 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000005139 204.0
HKD1_k127_4593910_67 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
HKD1_k127_4593910_68 - - - - 0.00000000000000000000000000000000000000000000000000000008792 209.0
HKD1_k127_4593910_69 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000101 193.0
HKD1_k127_4593910_7 Aldehyde dehydrogenase family K00138 - - 3.522e-221 694.0
HKD1_k127_4593910_70 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000443 193.0
HKD1_k127_4593910_71 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000008477 191.0
HKD1_k127_4593910_72 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000006336 194.0
HKD1_k127_4593910_73 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000002849 184.0
HKD1_k127_4593910_74 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000008941 175.0
HKD1_k127_4593910_75 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000004874 188.0
HKD1_k127_4593910_76 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000003439 173.0
HKD1_k127_4593910_77 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000003994 175.0
HKD1_k127_4593910_78 - - - - 0.000000000000000000000000000000000000000002743 161.0
HKD1_k127_4593910_79 May be involved in cell division - - - 0.0000000000000000000000000000000000000005735 162.0
HKD1_k127_4593910_8 homoserine dehydrogenase - - - 4.778e-212 668.0
HKD1_k127_4593910_80 cytochrome K08738 - - 0.0000000000000000000000000000000000000009756 156.0
HKD1_k127_4593910_81 - - - - 0.000000000000000000000000000000000000001329 162.0
HKD1_k127_4593910_83 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000001868 136.0
HKD1_k127_4593910_84 Cytochrome c - - - 0.0000000000000000000000000000007185 127.0
HKD1_k127_4593910_85 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000001399 134.0
HKD1_k127_4593910_86 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000005765 124.0
HKD1_k127_4593910_87 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000002338 126.0
HKD1_k127_4593910_88 LysM domain - - - 0.0000000000000000000000000003614 121.0
HKD1_k127_4593910_89 - - - - 0.0000000000000000000000000176 110.0
HKD1_k127_4593910_9 Cytochrome c - - - 1.34e-198 649.0
HKD1_k127_4593910_90 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000001828 121.0
HKD1_k127_4593910_91 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000002503 115.0
HKD1_k127_4593910_92 Domain of unknown function (DUF4184) - - - 0.0000000000000000000000003025 118.0
HKD1_k127_4593910_93 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000006816 100.0
HKD1_k127_4593910_94 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000001402 91.0
HKD1_k127_4593910_95 - - - - 0.000000000000000443 83.0
HKD1_k127_4593910_96 Carboxypeptidase regulatory-like domain - - - 0.000000000000005022 87.0
HKD1_k127_4593910_97 PFAM NHL repeat containing protein - - - 0.00000000000001334 76.0
HKD1_k127_4593910_98 GrpE K03687 - - 0.00000000000004046 80.0
HKD1_k127_4593910_99 Prokaryotic cytochrome b561 - - - 0.0000000000001871 80.0
HKD1_k127_4657977_0 Flavin containing amine oxidoreductase - - - 1.214e-264 824.0
HKD1_k127_4657977_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 534.0
HKD1_k127_4657977_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.00000000000002701 87.0
HKD1_k127_4657977_11 Esterase - - - 0.000000001218 61.0
HKD1_k127_4657977_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0001856 53.0
HKD1_k127_4657977_2 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 511.0
HKD1_k127_4657977_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 447.0
HKD1_k127_4657977_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 322.0
HKD1_k127_4657977_5 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000003713 225.0
HKD1_k127_4657977_6 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000004978 157.0
HKD1_k127_4657977_7 - - - - 0.0000000000000000000000000000000000004988 144.0
HKD1_k127_4657977_8 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000005238 119.0
HKD1_k127_4657977_9 family UPF0324 - - - 0.0000000000000000000000000005649 119.0
HKD1_k127_4693985_0 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 553.0
HKD1_k127_4693985_1 ISPsy14, transposition helper protein - - - 0.0000000000000000000000000000000000000000000002245 172.0
HKD1_k127_4693985_2 ISPsy14, transposition helper protein - - - 0.00000000000000000000000006874 116.0
HKD1_k127_4997913_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
HKD1_k127_4997913_1 PFAM SCP-like extracellular - - - 0.000000000000000000000000000001634 131.0
HKD1_k127_5051050_0 RHS protein - - - 0.00000000000000000000000000000009216 136.0
HKD1_k127_5071456_0 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002718 256.0
HKD1_k127_5071456_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000001346 199.0
HKD1_k127_5083412_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000175 288.0
HKD1_k127_5083412_1 methyltransferase - - - 0.0000000000000000000004587 105.0
HKD1_k127_5162203_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1027.0
HKD1_k127_5162203_1 MutL protein - - - 5.838e-290 901.0
HKD1_k127_5162203_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 356.0
HKD1_k127_5162203_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 341.0
HKD1_k127_5162203_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 326.0
HKD1_k127_5162203_13 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 314.0
HKD1_k127_5162203_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 293.0
HKD1_k127_5162203_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001486 260.0
HKD1_k127_5162203_16 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 262.0
HKD1_k127_5162203_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001191 263.0
HKD1_k127_5162203_18 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 262.0
HKD1_k127_5162203_19 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003182 259.0
HKD1_k127_5162203_2 DNA topological change K03168 - 5.99.1.2 8.388e-232 742.0
HKD1_k127_5162203_20 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005646 236.0
HKD1_k127_5162203_21 - - - - 0.0000000000000000000000000000000000000000000000000000000001474 214.0
HKD1_k127_5162203_22 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000003026 187.0
HKD1_k127_5162203_24 - - - - 0.0000000000000000000000000000000000000002484 163.0
HKD1_k127_5162203_25 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000007938 150.0
HKD1_k127_5162203_27 NIPSNAP - - - 0.0000000000000000000000000000000000035 141.0
HKD1_k127_5162203_28 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000006755 121.0
HKD1_k127_5162203_29 Helix-hairpin-helix motif - - - 0.00000000000000000004118 98.0
HKD1_k127_5162203_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 520.0
HKD1_k127_5162203_30 - - - - 0.00000000000000001206 89.0
HKD1_k127_5162203_31 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000002379 84.0
HKD1_k127_5162203_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 517.0
HKD1_k127_5162203_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 503.0
HKD1_k127_5162203_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 466.0
HKD1_k127_5162203_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 429.0
HKD1_k127_5162203_8 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 419.0
HKD1_k127_5162203_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 398.0
HKD1_k127_5206727_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 8.284e-299 925.0
HKD1_k127_5206727_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 6.202e-272 849.0
HKD1_k127_5206727_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 507.0
HKD1_k127_5206727_11 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 466.0
HKD1_k127_5206727_12 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 452.0
HKD1_k127_5206727_13 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 431.0
HKD1_k127_5206727_14 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 441.0
HKD1_k127_5206727_15 Mur ligase middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 436.0
HKD1_k127_5206727_16 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 415.0
HKD1_k127_5206727_17 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 409.0
HKD1_k127_5206727_18 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
HKD1_k127_5206727_19 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 409.0
HKD1_k127_5206727_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.272e-256 807.0
HKD1_k127_5206727_20 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 399.0
HKD1_k127_5206727_21 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 372.0
HKD1_k127_5206727_22 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 367.0
HKD1_k127_5206727_23 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 357.0
HKD1_k127_5206727_24 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HKD1_k127_5206727_25 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 336.0
HKD1_k127_5206727_26 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 340.0
HKD1_k127_5206727_27 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 335.0
HKD1_k127_5206727_28 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 331.0
HKD1_k127_5206727_29 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 344.0
HKD1_k127_5206727_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.99e-235 740.0
HKD1_k127_5206727_30 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 340.0
HKD1_k127_5206727_31 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 353.0
HKD1_k127_5206727_32 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 335.0
HKD1_k127_5206727_33 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 318.0
HKD1_k127_5206727_34 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 329.0
HKD1_k127_5206727_35 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 299.0
HKD1_k127_5206727_36 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
HKD1_k127_5206727_37 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004731 285.0
HKD1_k127_5206727_38 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 276.0
HKD1_k127_5206727_39 allophanate hydrolase subunit 2 K01457,K01941,K06350 - 3.5.1.54,6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003475 261.0
HKD1_k127_5206727_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.453e-228 713.0
HKD1_k127_5206727_40 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000147 265.0
HKD1_k127_5206727_41 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004325 254.0
HKD1_k127_5206727_42 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000003565 238.0
HKD1_k127_5206727_43 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000000000003419 217.0
HKD1_k127_5206727_44 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000001809 213.0
HKD1_k127_5206727_45 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000001597 207.0
HKD1_k127_5206727_46 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000002629 211.0
HKD1_k127_5206727_47 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000005153 201.0
HKD1_k127_5206727_48 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000002551 206.0
HKD1_k127_5206727_49 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000006907 209.0
HKD1_k127_5206727_5 amino acid K03294 - - 1.433e-227 714.0
HKD1_k127_5206727_50 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000001125 198.0
HKD1_k127_5206727_51 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000001586 184.0
HKD1_k127_5206727_52 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000003043 186.0
HKD1_k127_5206727_53 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000001986 176.0
HKD1_k127_5206727_54 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000005159 166.0
HKD1_k127_5206727_55 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000004068 168.0
HKD1_k127_5206727_56 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000007683 171.0
HKD1_k127_5206727_57 Haem-degrading - - - 0.000000000000000000000000000000000001226 144.0
HKD1_k127_5206727_58 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000002812 142.0
HKD1_k127_5206727_59 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000008649 138.0
HKD1_k127_5206727_6 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 604.0
HKD1_k127_5206727_60 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000003633 131.0
HKD1_k127_5206727_62 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000001033 121.0
HKD1_k127_5206727_63 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000001796 104.0
HKD1_k127_5206727_64 Pilus assembly protein, PilO K02664 - - 0.000000000000000000009422 103.0
HKD1_k127_5206727_66 Protein of unknown function (DUF2905) - - - 0.00000000000001291 75.0
HKD1_k127_5206727_67 SNARE associated Golgi protein - - - 0.000000000004958 71.0
HKD1_k127_5206727_68 Fimbrial assembly protein (PilN) K02663 - - 0.00000000003495 74.0
HKD1_k127_5206727_69 Tetratricopeptide repeats - - - 0.00000000005467 73.0
HKD1_k127_5206727_7 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 589.0
HKD1_k127_5206727_70 HEAT repeats - - - 0.0000000001377 74.0
HKD1_k127_5206727_71 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.000000002555 67.0
HKD1_k127_5206727_72 Pilus assembly protein, PilP K02665 - - 0.000002324 57.0
HKD1_k127_5206727_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 598.0
HKD1_k127_5206727_9 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 505.0
HKD1_k127_5210626_0 Product type h extrachromosomal origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 544.0
HKD1_k127_522228_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000176 295.0
HKD1_k127_5266984_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1479.0
HKD1_k127_5266984_1 Dehydrogenase K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 479.0
HKD1_k127_5266984_10 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002473 284.0
HKD1_k127_5266984_11 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004252 260.0
HKD1_k127_5266984_12 UvrD/REP helicase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000001064 244.0
HKD1_k127_5266984_13 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000004773 211.0
HKD1_k127_5266984_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000003664 132.0
HKD1_k127_5266984_15 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.0000000000000000000000006237 123.0
HKD1_k127_5266984_16 Mannosyl-3-phosphoglycerate phosphatase K07026,K15918 - 2.7.1.31,3.1.3.70 0.000000000000000000000002727 113.0
HKD1_k127_5266984_17 YCII-related domain - - - 0.0000000000000000000000143 104.0
HKD1_k127_5266984_18 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000001201 92.0
HKD1_k127_5266984_19 pyridoxamine 5-phosphate - - - 0.000000000001135 75.0
HKD1_k127_5266984_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 446.0
HKD1_k127_5266984_20 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000001861 72.0
HKD1_k127_5266984_21 - - - - 0.00000000008988 68.0
HKD1_k127_5266984_23 DnaJ central domain K09504 GO:0000002,GO:0000122,GO:0001775,GO:0001776,GO:0001932,GO:0001933,GO:0001941,GO:0001959,GO:0001960,GO:0002119,GO:0002164,GO:0002260,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0005102,GO:0005113,GO:0005126,GO:0005133,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006355,GO:0006357,GO:0006457,GO:0006469,GO:0006725,GO:0006807,GO:0006915,GO:0006919,GO:0006924,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007264,GO:0007275,GO:0007528,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0009058,GO:0009059,GO:0009295,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0012501,GO:0016020,GO:0016043,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030162,GO:0030217,GO:0030234,GO:0030544,GO:0030695,GO:0030971,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031347,GO:0031348,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031594,GO:0031647,GO:0031974,GO:0032042,GO:0032088,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033036,GO:0033077,GO:0033673,GO:0034097,GO:0034341,GO:0034613,GO:0034641,GO:0034645,GO:0035556,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042645,GO:0042981,GO:0043029,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043113,GO:0043122,GO:0043124,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043433,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045202,GO:0045211,GO:0045321,GO:0045785,GO:0045824,GO:0045859,GO:0045861,GO:0045862,GO:0045892,GO:0045934,GO:0045936,GO:0046483,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050670,GO:0050671,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051059,GO:0051082,GO:0051090,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051641,GO:0051668,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060548,GO:0060589,GO:0060759,GO:0060761,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070227,GO:0070231,GO:0070663,GO:0070665,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071887,GO:0071944,GO:0072657,GO:0080090,GO:0080134,GO:0090304,GO:0097060,GO:0098590,GO:0098772,GO:0098794,GO:0099173,GO:1901360,GO:1901576,GO:1902531,GO:1902532,GO:1902679,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1990782,GO:2000112,GO:2000113,GO:2000116,GO:2000117,GO:2001056,GO:2001141 - 0.0003058 49.0
HKD1_k127_5266984_24 - - - - 0.0004737 49.0
HKD1_k127_5266984_3 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 433.0
HKD1_k127_5266984_4 HlyD family secretion protein K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 412.0
HKD1_k127_5266984_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 387.0
HKD1_k127_5266984_6 phosphorelay signal transduction system K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 387.0
HKD1_k127_5266984_7 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HKD1_k127_5266984_8 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 313.0
HKD1_k127_5266984_9 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 298.0
HKD1_k127_5309482_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 348.0
HKD1_k127_5309482_1 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000041 289.0
HKD1_k127_5312949_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 606.0
HKD1_k127_5312949_1 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 534.0
HKD1_k127_5312949_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001091 274.0
HKD1_k127_5312949_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003056 270.0
HKD1_k127_5312949_12 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000001231 226.0
HKD1_k127_5312949_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000007342 221.0
HKD1_k127_5312949_14 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000004235 218.0
HKD1_k127_5312949_15 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000001571 194.0
HKD1_k127_5312949_16 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000003928 190.0
HKD1_k127_5312949_18 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000001645 138.0
HKD1_k127_5312949_19 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000001457 76.0
HKD1_k127_5312949_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 525.0
HKD1_k127_5312949_20 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.000000000001821 79.0
HKD1_k127_5312949_21 calcium ion binding K17307 - - 0.0000000005598 73.0
HKD1_k127_5312949_22 - - - - 0.00000006323 64.0
HKD1_k127_5312949_23 protein kinase activity - - - 0.000000641 63.0
HKD1_k127_5312949_24 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.00003257 56.0
HKD1_k127_5312949_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 514.0
HKD1_k127_5312949_4 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 493.0
HKD1_k127_5312949_6 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 445.0
HKD1_k127_5312949_7 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 417.0
HKD1_k127_5312949_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD1_k127_5312949_9 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007551 278.0
HKD1_k127_5322562_0 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 357.0
HKD1_k127_5322562_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004053 267.0
HKD1_k127_5322562_2 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000001797 208.0
HKD1_k127_5322562_3 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000001777 198.0
HKD1_k127_5322562_5 - - - - 0.00005332 45.0
HKD1_k127_5331746_0 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 523.0
HKD1_k127_5331746_1 Branched-chain amino acid transport system / permease component K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 464.0
HKD1_k127_5338370_0 DNA topological change K03168 - 5.99.1.2 0.0 1044.0
HKD1_k127_5338370_1 radical SAM domain protein - - - 2.363e-277 864.0
HKD1_k127_5338370_10 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 539.0
HKD1_k127_5338370_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 542.0
HKD1_k127_5338370_12 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 481.0
HKD1_k127_5338370_13 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 471.0
HKD1_k127_5338370_14 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 442.0
HKD1_k127_5338370_15 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 421.0
HKD1_k127_5338370_16 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 392.0
HKD1_k127_5338370_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
HKD1_k127_5338370_18 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 369.0
HKD1_k127_5338370_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 366.0
HKD1_k127_5338370_2 DNA topological change K03168 - 5.99.1.2 7.785e-250 794.0
HKD1_k127_5338370_20 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 359.0
HKD1_k127_5338370_21 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 357.0
HKD1_k127_5338370_22 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 357.0
HKD1_k127_5338370_23 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
HKD1_k127_5338370_24 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005499 276.0
HKD1_k127_5338370_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004738 272.0
HKD1_k127_5338370_26 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
HKD1_k127_5338370_27 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004079 282.0
HKD1_k127_5338370_28 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
HKD1_k127_5338370_29 - - - - 0.0000000000000000000000000000000000000000000000000000000002951 218.0
HKD1_k127_5338370_3 Phosphoenolpyruvate synthase K01007 - 2.7.9.2 2.923e-247 797.0
HKD1_k127_5338370_30 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000006472 191.0
HKD1_k127_5338370_31 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000009994 188.0
HKD1_k127_5338370_32 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000001274 175.0
HKD1_k127_5338370_33 - - - - 0.0000000000000000000000000000000000000000002234 175.0
HKD1_k127_5338370_34 Ankyrin 1, erythrocytic K10380,K15502,K15503 - - 0.00000000000000000000000000000000000001647 163.0
HKD1_k127_5338370_35 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000003159 149.0
HKD1_k127_5338370_36 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000001201 146.0
HKD1_k127_5338370_37 Tetratricopeptide repeat - - - 0.000000000000000000000003071 118.0
HKD1_k127_5338370_38 Protein of unknown function, DUF481 K07283 - - 0.00000002939 65.0
HKD1_k127_5338370_39 COG4308 Limonene-1,2-epoxide hydrolase K10533 - 3.3.2.8 0.00000004994 64.0
HKD1_k127_5338370_4 Protein of unknown function (DUF1552) - - - 1.344e-226 713.0
HKD1_k127_5338370_41 amine dehydrogenase activity - - - 0.000009829 58.0
HKD1_k127_5338370_42 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00001864 51.0
HKD1_k127_5338370_43 Cupin - - - 0.00003798 54.0
HKD1_k127_5338370_44 - - - - 0.00004451 51.0
HKD1_k127_5338370_45 PFAM TonB-dependent Receptor Plug - - - 0.0004181 48.0
HKD1_k127_5338370_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 608.0
HKD1_k127_5338370_6 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 582.0
HKD1_k127_5338370_7 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 580.0
HKD1_k127_5338370_8 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 577.0
HKD1_k127_5338370_9 Spermine spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 572.0
HKD1_k127_5398385_0 LOR/SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 484.0
HKD1_k127_5398385_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 463.0
HKD1_k127_5398385_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 296.0
HKD1_k127_5398385_11 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005214 263.0
HKD1_k127_5398385_12 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
HKD1_k127_5398385_13 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000002649 240.0
HKD1_k127_5398385_14 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000003286 184.0
HKD1_k127_5398385_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000003914 188.0
HKD1_k127_5398385_16 - - - - 0.00000000000000000000000000000000000000000000152 187.0
HKD1_k127_5398385_17 Cytochrome c - - - 0.00000000000000000000000000000000000003511 147.0
HKD1_k127_5398385_18 Cytochrome C' - - - 0.00000000000000000000000000000000001276 143.0
HKD1_k127_5398385_19 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000007097 138.0
HKD1_k127_5398385_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 439.0
HKD1_k127_5398385_21 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000006666 138.0
HKD1_k127_5398385_22 lipoprotein localization to outer membrane - - - 0.000000000000000000000000101 118.0
HKD1_k127_5398385_23 peptidyl-tyrosine sulfation K13992 - - 0.000000000000000000000004943 110.0
HKD1_k127_5398385_24 recA bacterial DNA recombination protein - - - 0.00000000000000006628 90.0
HKD1_k127_5398385_25 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000002064 80.0
HKD1_k127_5398385_26 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000004952 65.0
HKD1_k127_5398385_27 Disulphide bond corrector protein DsbC - - - 0.0000021 57.0
HKD1_k127_5398385_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 429.0
HKD1_k127_5398385_4 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 400.0
HKD1_k127_5398385_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 371.0
HKD1_k127_5398385_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 353.0
HKD1_k127_5398385_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 350.0
HKD1_k127_5398385_8 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 323.0
HKD1_k127_5398385_9 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 313.0
HKD1_k127_5429025_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K03737 - 1.2.7.1 0.0 2040.0
HKD1_k127_5429025_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1274.0
HKD1_k127_5429025_10 response regulator K02481,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 477.0
HKD1_k127_5429025_11 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 446.0
HKD1_k127_5429025_12 biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 437.0
HKD1_k127_5429025_13 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 424.0
HKD1_k127_5429025_14 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 411.0
HKD1_k127_5429025_15 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 389.0
HKD1_k127_5429025_16 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 357.0
HKD1_k127_5429025_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 343.0
HKD1_k127_5429025_18 outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 345.0
HKD1_k127_5429025_19 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 330.0
HKD1_k127_5429025_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1179.0
HKD1_k127_5429025_20 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 327.0
HKD1_k127_5429025_21 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 308.0
HKD1_k127_5429025_22 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 305.0
HKD1_k127_5429025_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 312.0
HKD1_k127_5429025_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 289.0
HKD1_k127_5429025_25 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009328 293.0
HKD1_k127_5429025_26 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003736 278.0
HKD1_k127_5429025_27 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 275.0
HKD1_k127_5429025_28 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000003961 277.0
HKD1_k127_5429025_29 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000468 275.0
HKD1_k127_5429025_3 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 3.571e-307 962.0
HKD1_k127_5429025_30 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000367 257.0
HKD1_k127_5429025_31 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003304 265.0
HKD1_k127_5429025_32 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
HKD1_k127_5429025_33 Bile acid K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
HKD1_k127_5429025_34 ribonuclease inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004217 236.0
HKD1_k127_5429025_35 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000008685 223.0
HKD1_k127_5429025_36 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008972 237.0
HKD1_k127_5429025_37 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000011 224.0
HKD1_k127_5429025_38 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000000000000000000000000000003162 228.0
HKD1_k127_5429025_39 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000759 231.0
HKD1_k127_5429025_4 PFAM Prolyl oligopeptidase family - - - 1.439e-233 740.0
HKD1_k127_5429025_40 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000003518 228.0
HKD1_k127_5429025_41 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000002929 225.0
HKD1_k127_5429025_42 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000004803 205.0
HKD1_k127_5429025_43 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000004773 211.0
HKD1_k127_5429025_44 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000004914 189.0
HKD1_k127_5429025_45 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000007568 187.0
HKD1_k127_5429025_46 - - - - 0.0000000000000000000000000000000000000000000000000007771 198.0
HKD1_k127_5429025_47 - - - - 0.000000000000000000000000000000000000000000000000005814 193.0
HKD1_k127_5429025_48 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000008329 176.0
HKD1_k127_5429025_49 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000000000004475 178.0
HKD1_k127_5429025_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.008e-220 694.0
HKD1_k127_5429025_50 Universal stress protein family - - - 0.000000000000000000000000000000000000000000007397 166.0
HKD1_k127_5429025_51 - - - - 0.0000000000000000000000000000000000000000002119 168.0
HKD1_k127_5429025_52 Transport Permease Protein K01992 - - 0.000000000000000000000000000000000000000007615 167.0
HKD1_k127_5429025_53 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000002714 171.0
HKD1_k127_5429025_54 EVE domain - - - 0.00000000000000000000000000000000000000004228 156.0
HKD1_k127_5429025_55 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.00000000000000000000000000000000000000005098 169.0
HKD1_k127_5429025_56 Membrane - - - 0.000000000000000000000000000000008239 132.0
HKD1_k127_5429025_57 - - - - 0.00000000000000000000000000003227 126.0
HKD1_k127_5429025_58 Outer membrane efflux protein - - - 0.0000000000000000000000005143 119.0
HKD1_k127_5429025_59 - - - - 0.0000000000000000000006492 108.0
HKD1_k127_5429025_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 569.0
HKD1_k127_5429025_60 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.000000000000000000009023 103.0
HKD1_k127_5429025_61 Phospholipase/Carboxylesterase - - - 0.00000000000000002696 93.0
HKD1_k127_5429025_63 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000152 86.0
HKD1_k127_5429025_64 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.00000000000003265 76.0
HKD1_k127_5429025_66 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000008388 76.0
HKD1_k127_5429025_67 Protein of unknown function (DUF1648) - - - 0.0000005795 59.0
HKD1_k127_5429025_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 505.0
HKD1_k127_5429025_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 479.0
HKD1_k127_5429025_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 471.0
HKD1_k127_5445204_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 543.0
HKD1_k127_5445204_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 449.0
HKD1_k127_5445204_2 XdhC Rossmann domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 330.0
HKD1_k127_5445204_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000007496 193.0
HKD1_k127_5445204_4 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000002128 169.0
HKD1_k127_5558077_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1189.0
HKD1_k127_5558077_1 AcrB/AcrD/AcrF family - - - 0.0 1156.0
HKD1_k127_5558077_10 Cupin domain protein - - - 0.000000000000000000000000000002112 125.0
HKD1_k127_5558077_11 cheY-homologous receiver domain - - - 0.00000000000000000000000000115 117.0
HKD1_k127_5558077_12 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000005404 107.0
HKD1_k127_5558077_13 Sulfurtransferase - - - 0.000000000001535 78.0
HKD1_k127_5558077_14 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000002805 70.0
HKD1_k127_5558077_15 alginic acid biosynthetic process K10297 - - 0.000003752 49.0
HKD1_k127_5558077_16 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000817 47.0
HKD1_k127_5558077_2 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
HKD1_k127_5558077_3 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004924 287.0
HKD1_k127_5558077_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000009748 239.0
HKD1_k127_5558077_5 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000004126 215.0
HKD1_k127_5558077_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000001366 200.0
HKD1_k127_5558077_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000004359 185.0
HKD1_k127_5558077_8 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002144 151.0
HKD1_k127_5670009_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 340.0
HKD1_k127_5670009_1 - - - - 0.000000000000000000000008473 103.0
HKD1_k127_5670009_2 Methyltransferase domain - - - 0.0000000000657 67.0
HKD1_k127_5702469_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1112.0
HKD1_k127_5702469_1 Phosphoenolpyruvate carboxykinase - - - 1.491e-299 923.0
HKD1_k127_5702469_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 283.0
HKD1_k127_5702469_11 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000378 272.0
HKD1_k127_5702469_12 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
HKD1_k127_5702469_13 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
HKD1_k127_5702469_14 molybdopterin cofactor binding K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000003573 253.0
HKD1_k127_5702469_15 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000007975 250.0
HKD1_k127_5702469_16 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000000000005053 181.0
HKD1_k127_5702469_17 amine dehydrogenase activity - - - 0.000000000000000000000000000004035 133.0
HKD1_k127_5702469_18 TonB dependent receptor - - - 0.000000000000000000004656 107.0
HKD1_k127_5702469_19 Calcineurin-like phosphoesterase - - - 0.00000000000000005443 93.0
HKD1_k127_5702469_2 Bacterial transcriptional activator domain - - - 1.716e-242 785.0
HKD1_k127_5702469_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000001174 69.0
HKD1_k127_5702469_22 - - - - 0.0000004201 59.0
HKD1_k127_5702469_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000006957 60.0
HKD1_k127_5702469_24 O-methyltransferase K20421 - 2.1.1.303 0.000001715 58.0
HKD1_k127_5702469_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 538.0
HKD1_k127_5702469_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 499.0
HKD1_k127_5702469_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 450.0
HKD1_k127_5702469_6 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 383.0
HKD1_k127_5702469_7 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 379.0
HKD1_k127_5702469_8 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 361.0
HKD1_k127_5702469_9 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 324.0
HKD1_k127_6063910_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.03e-201 638.0
HKD1_k127_6063910_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005522 278.0
HKD1_k127_6063910_2 enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000155 219.0
HKD1_k127_6063910_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000001074 208.0
HKD1_k127_6063910_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000011 114.0
HKD1_k127_6063910_5 Transposase K07485 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000001781 82.0
HKD1_k127_6063910_6 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000006878 70.0
HKD1_k127_6063910_7 - - - - 0.00009145 53.0
HKD1_k127_6162312_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1031.0
HKD1_k127_6162312_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 4.215e-241 762.0
HKD1_k127_6162312_10 KR domain - - - 0.00000000000000000000000000000000000000006598 164.0
HKD1_k127_6162312_11 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000636 140.0
HKD1_k127_6162312_12 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000000000521 111.0
HKD1_k127_6162312_13 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000009707 102.0
HKD1_k127_6162312_14 - - - - 0.00000000000001352 83.0
HKD1_k127_6162312_15 Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051082,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00004094 54.0
HKD1_k127_6162312_2 PQQ-like domain - - - 1.055e-217 698.0
HKD1_k127_6162312_3 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 429.0
HKD1_k127_6162312_4 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 381.0
HKD1_k127_6162312_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 381.0
HKD1_k127_6162312_6 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
HKD1_k127_6162312_7 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 306.0
HKD1_k127_6162312_8 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000001768 193.0
HKD1_k127_6162312_9 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000005594 186.0
HKD1_k127_6194688_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1432.0
HKD1_k127_6194688_1 secondary active sulfate transmembrane transporter activity K06901 - - 1.843e-214 676.0
HKD1_k127_6194688_10 acr, cog1993 K09137 - - 0.00000000000000000000000001231 123.0
HKD1_k127_6194688_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000006189 99.0
HKD1_k127_6194688_12 Protein of unknown function DUF58 - - - 0.000000000008344 78.0
HKD1_k127_6194688_13 von Willebrand factor type A domain K07114 - - 0.0000000001129 74.0
HKD1_k127_6194688_14 PFAM von Willebrand factor type A domain K07114 - - 0.00001191 57.0
HKD1_k127_6194688_15 Putative zinc-finger - - - 0.0007889 49.0
HKD1_k127_6194688_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 381.0
HKD1_k127_6194688_3 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 340.0
HKD1_k127_6194688_4 COG0714 MoxR-like ATPases K03924 - - 0.00000000000000000000000000000000000000000000000000175 195.0
HKD1_k127_6194688_5 - - - - 0.0000000000000000000000000000000000000000000000008748 184.0
HKD1_k127_6194688_6 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000003824 164.0
HKD1_k127_6194688_7 - - - - 0.0000000000000000000000000000000000002374 152.0
HKD1_k127_6194688_8 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000008928 121.0
HKD1_k127_6194688_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000516 119.0
HKD1_k127_6209372_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 531.0
HKD1_k127_6209372_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 507.0
HKD1_k127_6209372_2 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
HKD1_k127_6209372_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 353.0
HKD1_k127_6209372_4 Belongs to the ompA family - - - 0.00000000000000000000000000000007919 133.0
HKD1_k127_6209372_5 PFAM von Willebrand factor type A - - - 0.000000000000000000000014 113.0
HKD1_k127_6209372_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000009038 91.0
HKD1_k127_6209372_7 ACT domain - - - 0.0000000007506 65.0
HKD1_k127_6209372_8 2Fe-2S -binding - - - 0.00005664 49.0
HKD1_k127_6223113_0 AcrB/AcrD/AcrF family - - - 0.0 1167.0
HKD1_k127_6223113_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1029.0
HKD1_k127_6223113_10 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 338.0
HKD1_k127_6223113_11 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 325.0
HKD1_k127_6223113_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 305.0
HKD1_k127_6223113_13 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002178 279.0
HKD1_k127_6223113_14 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000001696 222.0
HKD1_k127_6223113_15 Transcriptional regulator - - - 0.00000000000000000000000000000000007466 145.0
HKD1_k127_6223113_16 ioli protein K06606 - 5.3.99.11 0.000000000000000000001257 107.0
HKD1_k127_6223113_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000004275 66.0
HKD1_k127_6223113_2 DNA topological change - - - 6.429e-253 805.0
HKD1_k127_6223113_3 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 1.959e-217 684.0
HKD1_k127_6223113_4 Dehydrogenase K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 542.0
HKD1_k127_6223113_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 477.0
HKD1_k127_6223113_6 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 441.0
HKD1_k127_6223113_7 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 401.0
HKD1_k127_6223113_8 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 375.0
HKD1_k127_6223113_9 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 357.0
HKD1_k127_6229594_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 514.0
HKD1_k127_6229594_1 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 399.0
HKD1_k127_6229594_2 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 355.0
HKD1_k127_6229594_3 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.00000000000000000000000000000000000000005806 166.0
HKD1_k127_6229594_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000712 161.0
HKD1_k127_6229594_5 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.000000000000000000000000002994 119.0
HKD1_k127_6229594_6 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0002932 45.0
HKD1_k127_6229827_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 318.0
HKD1_k127_6229827_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000004581 63.0
HKD1_k127_6229827_2 Prokaryotic N-terminal methylation motif K08084 - - 0.0002462 50.0
HKD1_k127_6229827_3 pilus assembly protein PilW - - - 0.0003605 50.0
HKD1_k127_6246385_0 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 584.0
HKD1_k127_6246385_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 354.0
HKD1_k127_6246385_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000627 257.0
HKD1_k127_6246385_3 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003966 245.0
HKD1_k127_6246385_4 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
HKD1_k127_6246385_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009211 248.0
HKD1_k127_6246385_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000002211 194.0
HKD1_k127_6246385_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000004279 117.0
HKD1_k127_6246385_8 NlpC P60 family protein - - - 0.0000000000000000000000000001161 122.0
HKD1_k127_6246385_9 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000002036 64.0
HKD1_k127_6296262_0 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 425.0
HKD1_k127_6296262_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000007295 71.0
HKD1_k127_6296262_3 AMP-binding enzyme C-terminal domain - - - 0.000001149 50.0
HKD1_k127_6319242_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1138.0
HKD1_k127_6319242_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.557e-227 710.0
HKD1_k127_6319242_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 462.0
HKD1_k127_6319242_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 421.0
HKD1_k127_6319242_12 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 392.0
HKD1_k127_6319242_13 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 384.0
HKD1_k127_6319242_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 396.0
HKD1_k127_6319242_15 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 351.0
HKD1_k127_6319242_16 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 354.0
HKD1_k127_6319242_17 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 340.0
HKD1_k127_6319242_18 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 342.0
HKD1_k127_6319242_19 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 327.0
HKD1_k127_6319242_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.307e-219 698.0
HKD1_k127_6319242_20 Coenzyme A transferase K01027,K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
HKD1_k127_6319242_21 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 325.0
HKD1_k127_6319242_22 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 312.0
HKD1_k127_6319242_23 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 301.0
HKD1_k127_6319242_24 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 311.0
HKD1_k127_6319242_25 PFAM FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 308.0
HKD1_k127_6319242_26 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 297.0
HKD1_k127_6319242_27 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 287.0
HKD1_k127_6319242_28 alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002459 288.0
HKD1_k127_6319242_29 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005858 289.0
HKD1_k127_6319242_3 Ftsk_gamma K03466 - - 1.028e-198 644.0
HKD1_k127_6319242_30 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000006161 259.0
HKD1_k127_6319242_31 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000002266 281.0
HKD1_k127_6319242_32 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000007032 256.0
HKD1_k127_6319242_33 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000316 278.0
HKD1_k127_6319242_34 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005744 255.0
HKD1_k127_6319242_35 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000009104 250.0
HKD1_k127_6319242_36 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
HKD1_k127_6319242_37 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000003539 254.0
HKD1_k127_6319242_38 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000003306 242.0
HKD1_k127_6319242_39 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000004083 223.0
HKD1_k127_6319242_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.111e-195 631.0
HKD1_k127_6319242_40 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000114 227.0
HKD1_k127_6319242_41 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000006985 220.0
HKD1_k127_6319242_42 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000003188 223.0
HKD1_k127_6319242_43 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000002697 210.0
HKD1_k127_6319242_44 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001761 205.0
HKD1_k127_6319242_45 - - - - 0.000000000000000000000000000000000000000000000000000006404 203.0
HKD1_k127_6319242_46 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000003902 198.0
HKD1_k127_6319242_47 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000009837 187.0
HKD1_k127_6319242_48 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000002384 197.0
HKD1_k127_6319242_49 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000001014 177.0
HKD1_k127_6319242_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 573.0
HKD1_k127_6319242_50 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000001784 176.0
HKD1_k127_6319242_51 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000002661 175.0
HKD1_k127_6319242_52 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000000000001375 183.0
HKD1_k127_6319242_53 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000001493 168.0
HKD1_k127_6319242_54 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000009772 169.0
HKD1_k127_6319242_55 thioesterase K07107 - - 0.00000000000000000000000000000000001305 142.0
HKD1_k127_6319242_56 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000001478 149.0
HKD1_k127_6319242_57 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000002475 139.0
HKD1_k127_6319242_58 CoA binding domain K06929 - - 0.0000000000000000000000000000000008997 134.0
HKD1_k127_6319242_59 MlaD protein K02067 - - 0.000000000000000000000000000000002171 142.0
HKD1_k127_6319242_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 538.0
HKD1_k127_6319242_60 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000002307 138.0
HKD1_k127_6319242_61 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000002638 128.0
HKD1_k127_6319242_62 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000006059 126.0
HKD1_k127_6319242_63 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000003986 111.0
HKD1_k127_6319242_64 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000002294 107.0
HKD1_k127_6319242_65 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000001787 92.0
HKD1_k127_6319242_66 Tetratricopeptide repeat K05807 - - 0.000000000000000003903 94.0
HKD1_k127_6319242_67 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.00000000000000008517 87.0
HKD1_k127_6319242_68 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.0000000000000001073 85.0
HKD1_k127_6319242_69 SMART zinc finger CDGSH-type domain protein - - - 0.000000000000001592 79.0
HKD1_k127_6319242_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 489.0
HKD1_k127_6319242_70 COG0457 FOG TPR repeat - - - 0.000000000004708 78.0
HKD1_k127_6319242_71 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000004845 76.0
HKD1_k127_6319242_72 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000001288 74.0
HKD1_k127_6319242_73 YtxH-like protein - - - 0.000000002209 62.0
HKD1_k127_6319242_74 PFAM blue (type 1) copper domain protein - - - 0.0000471 53.0
HKD1_k127_6319242_75 Putative zinc-finger - - - 0.000189 53.0
HKD1_k127_6319242_76 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.0006705 49.0
HKD1_k127_6319242_8 alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
HKD1_k127_6319242_9 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 464.0
HKD1_k127_6357008_1 RAMP superfamily - - - 0.000000000000000000000000000000005441 135.0
HKD1_k127_6359640_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000008007 108.0
HKD1_k127_6359640_3 Cytochrome c K08738 - - 0.0000000000000004874 87.0
HKD1_k127_6359640_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00009347 49.0
HKD1_k127_6399816_0 Malate synthase K01638 - 2.3.3.9 3.328e-301 944.0
HKD1_k127_6399816_1 PQQ-like domain - - - 1.448e-231 730.0
HKD1_k127_6399816_10 translation initiation factor activity K20276 - - 0.0000000000000000000000002623 121.0
HKD1_k127_6399816_11 Protein tyrosine kinase - - - 0.0000000002965 73.0
HKD1_k127_6399816_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 394.0
HKD1_k127_6399816_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000001075 259.0
HKD1_k127_6399816_4 heme binding K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000002086 189.0
HKD1_k127_6399816_5 COG3258 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000001139 159.0
HKD1_k127_6399816_6 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000124 158.0
HKD1_k127_6399816_7 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000001154 159.0
HKD1_k127_6399816_8 von Willebrand factor, type A - - - 0.0000000000000000000000000000002745 134.0
HKD1_k127_6399816_9 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000009268 133.0
HKD1_k127_6403520_0 Radical SAM - - - 0.0 1161.0
HKD1_k127_6403520_1 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 2.837e-271 845.0
HKD1_k127_6403520_10 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 559.0
HKD1_k127_6403520_11 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 518.0
HKD1_k127_6403520_12 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 475.0
HKD1_k127_6403520_13 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 458.0
HKD1_k127_6403520_14 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 417.0
HKD1_k127_6403520_15 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 422.0
HKD1_k127_6403520_16 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 374.0
HKD1_k127_6403520_17 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 389.0
HKD1_k127_6403520_18 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 347.0
HKD1_k127_6403520_19 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 349.0
HKD1_k127_6403520_2 DNA topological change K03168 - 5.99.1.2 2.927e-239 764.0
HKD1_k127_6403520_20 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 312.0
HKD1_k127_6403520_21 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 308.0
HKD1_k127_6403520_22 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 304.0
HKD1_k127_6403520_23 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
HKD1_k127_6403520_24 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 290.0
HKD1_k127_6403520_25 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001144 307.0
HKD1_k127_6403520_26 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008536 274.0
HKD1_k127_6403520_27 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
HKD1_k127_6403520_28 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000006697 267.0
HKD1_k127_6403520_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 260.0
HKD1_k127_6403520_3 DNA topological change K03168 - 5.99.1.2 3.268e-236 762.0
HKD1_k127_6403520_30 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002675 282.0
HKD1_k127_6403520_31 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000003431 253.0
HKD1_k127_6403520_32 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004138 256.0
HKD1_k127_6403520_33 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
HKD1_k127_6403520_34 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000008597 234.0
HKD1_k127_6403520_35 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000663 220.0
HKD1_k127_6403520_36 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000002844 240.0
HKD1_k127_6403520_37 Transcriptional regulatory protein, C terminal K07668 - - 0.00000000000000000000000000000000000000000000000000001057 199.0
HKD1_k127_6403520_38 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000000000001615 181.0
HKD1_k127_6403520_39 - - - - 0.00000000000000000000000000000000000000000002748 171.0
HKD1_k127_6403520_4 DNA topological change K03168 - 5.99.1.2 6.507e-234 750.0
HKD1_k127_6403520_40 LemA family K03744 - - 0.00000000000000000000000000000000000000000008095 163.0
HKD1_k127_6403520_41 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000005654 164.0
HKD1_k127_6403520_42 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000000001167 158.0
HKD1_k127_6403520_43 urea catabolic process K01430 - 3.5.1.5 0.000000000000000000000000000000000000001091 153.0
HKD1_k127_6403520_44 NUDIX domain - - - 0.00000000000000000000000000000000000000227 154.0
HKD1_k127_6403520_45 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000001026 149.0
HKD1_k127_6403520_46 Damage-inducible protein DinB - - - 0.0000000000000000000000000000000000000164 151.0
HKD1_k127_6403520_47 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000625 149.0
HKD1_k127_6403520_48 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000002348 149.0
HKD1_k127_6403520_49 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.0000000000000000000000000000000000002518 151.0
HKD1_k127_6403520_5 - - - - 9.926e-222 710.0
HKD1_k127_6403520_50 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000003371 141.0
HKD1_k127_6403520_51 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000005856 153.0
HKD1_k127_6403520_52 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000007875 148.0
HKD1_k127_6403520_53 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000004091 144.0
HKD1_k127_6403520_54 GAF domain - - - 0.00000000000000000000000000000000009366 152.0
HKD1_k127_6403520_55 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000007857 138.0
HKD1_k127_6403520_56 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.000000000000000000000000000002703 125.0
HKD1_k127_6403520_57 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000003452 126.0
HKD1_k127_6403520_59 UreF - - - 0.00000000000000000042 96.0
HKD1_k127_6403520_6 Amino acid permease K03294 - - 1.067e-201 639.0
HKD1_k127_6403520_60 PFAM AIG2 family protein K20757 - 4.3.1.27 0.000000000000000001032 91.0
HKD1_k127_6403520_61 - - - - 0.00000000000000001889 95.0
HKD1_k127_6403520_62 - - - - 0.00000000000000003062 87.0
HKD1_k127_6403520_63 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000006187 89.0
HKD1_k127_6403520_64 Aspartyl protease - - - 0.000000000004767 79.0
HKD1_k127_6403520_65 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000001458 68.0
HKD1_k127_6403520_66 UreE urease accessory protein, N-terminal domain K03187 - - 0.00000005132 61.0
HKD1_k127_6403520_67 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000008723 59.0
HKD1_k127_6403520_68 Putative zinc-finger - - - 0.00007049 53.0
HKD1_k127_6403520_69 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000872 51.0
HKD1_k127_6403520_7 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 610.0
HKD1_k127_6403520_8 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 599.0
HKD1_k127_6403520_9 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 556.0
HKD1_k127_6528203_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.474e-295 919.0
HKD1_k127_6528203_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.61e-274 865.0
HKD1_k127_6528203_10 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 498.0
HKD1_k127_6528203_11 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 482.0
HKD1_k127_6528203_12 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 460.0
HKD1_k127_6528203_13 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 413.0
HKD1_k127_6528203_14 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 377.0
HKD1_k127_6528203_15 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 386.0
HKD1_k127_6528203_16 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 366.0
HKD1_k127_6528203_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 374.0
HKD1_k127_6528203_18 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 351.0
HKD1_k127_6528203_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 349.0
HKD1_k127_6528203_2 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 7.574e-215 677.0
HKD1_k127_6528203_20 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 342.0
HKD1_k127_6528203_21 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 333.0
HKD1_k127_6528203_22 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 344.0
HKD1_k127_6528203_23 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 327.0
HKD1_k127_6528203_24 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 316.0
HKD1_k127_6528203_25 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 325.0
HKD1_k127_6528203_26 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
HKD1_k127_6528203_27 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 298.0
HKD1_k127_6528203_28 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 295.0
HKD1_k127_6528203_29 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
HKD1_k127_6528203_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 6.035e-200 630.0
HKD1_k127_6528203_30 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001372 261.0
HKD1_k127_6528203_31 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
HKD1_k127_6528203_32 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
HKD1_k127_6528203_33 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000005658 188.0
HKD1_k127_6528203_34 Ferredoxin - - - 0.00000000000000000000000000000000000000000002856 165.0
HKD1_k127_6528203_35 PFAM phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000007189 168.0
HKD1_k127_6528203_36 mitochondrion morphogenesis K06195 - - 0.00000000000000000000000000000000000000001383 156.0
HKD1_k127_6528203_37 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000000005958 166.0
HKD1_k127_6528203_38 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000003948 150.0
HKD1_k127_6528203_39 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000003982 149.0
HKD1_k127_6528203_4 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 590.0
HKD1_k127_6528203_40 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000004004 138.0
HKD1_k127_6528203_41 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000003059 143.0
HKD1_k127_6528203_42 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000308 104.0
HKD1_k127_6528203_43 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000009157 109.0
HKD1_k127_6528203_44 - - - - 0.0000000000000000000007207 102.0
HKD1_k127_6528203_45 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000002336 97.0
HKD1_k127_6528203_47 Peptidase M56 - - - 0.0000001249 63.0
HKD1_k127_6528203_48 Methyltransferase small domain - - - 0.0000005286 60.0
HKD1_k127_6528203_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 587.0
HKD1_k127_6528203_50 Belongs to the peptidase S8 family - - - 0.0004558 53.0
HKD1_k127_6528203_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 535.0
HKD1_k127_6528203_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 523.0
HKD1_k127_6528203_8 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 507.0
HKD1_k127_6528203_9 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 505.0
HKD1_k127_6698441_0 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 312.0
HKD1_k127_6698441_1 - - - - 0.000000000000000000000000000000000000003451 151.0
HKD1_k127_6698441_2 LppP/LprE lipoprotein - - - 0.0000000000000000000000000000102 126.0
HKD1_k127_6942931_0 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000002482 138.0
HKD1_k127_6942931_2 Transposase K07483 - - 0.0000000000009715 73.0
HKD1_k127_6942931_3 Transposase (IS116 IS110 IS902 family) - - - 0.000002056 54.0
HKD1_k127_7019209_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1108.0
HKD1_k127_7019209_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.783e-247 782.0
HKD1_k127_7019209_10 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 481.0
HKD1_k127_7019209_100 Putative MetA-pathway of phenol degradation - - - 0.00000000009201 72.0
HKD1_k127_7019209_101 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000009831 69.0
HKD1_k127_7019209_102 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000023 55.0
HKD1_k127_7019209_103 - - - - 0.000003172 57.0
HKD1_k127_7019209_104 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000008332 52.0
HKD1_k127_7019209_105 Carboxypeptidase regulatory-like domain - - - 0.00004134 56.0
HKD1_k127_7019209_106 Tetratricopeptide repeat - - - 0.00009548 55.0
HKD1_k127_7019209_107 function. Source PGD - - - 0.0001903 51.0
HKD1_k127_7019209_108 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0003695 46.0
HKD1_k127_7019209_109 - - - - 0.0006363 46.0
HKD1_k127_7019209_11 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 467.0
HKD1_k127_7019209_12 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
HKD1_k127_7019209_13 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 455.0
HKD1_k127_7019209_14 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 452.0
HKD1_k127_7019209_15 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 473.0
HKD1_k127_7019209_16 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 423.0
HKD1_k127_7019209_17 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 413.0
HKD1_k127_7019209_18 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
HKD1_k127_7019209_19 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 407.0
HKD1_k127_7019209_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.701e-199 644.0
HKD1_k127_7019209_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 409.0
HKD1_k127_7019209_21 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 411.0
HKD1_k127_7019209_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 374.0
HKD1_k127_7019209_23 Deoxyhypusine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 372.0
HKD1_k127_7019209_24 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 357.0
HKD1_k127_7019209_25 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 358.0
HKD1_k127_7019209_26 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 348.0
HKD1_k127_7019209_27 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 336.0
HKD1_k127_7019209_28 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 347.0
HKD1_k127_7019209_29 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 332.0
HKD1_k127_7019209_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.132e-198 627.0
HKD1_k127_7019209_30 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 323.0
HKD1_k127_7019209_31 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 325.0
HKD1_k127_7019209_32 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 309.0
HKD1_k127_7019209_33 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 304.0
HKD1_k127_7019209_34 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 297.0
HKD1_k127_7019209_35 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 301.0
HKD1_k127_7019209_36 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
HKD1_k127_7019209_37 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003925 280.0
HKD1_k127_7019209_38 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000545 281.0
HKD1_k127_7019209_39 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000189 272.0
HKD1_k127_7019209_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 597.0
HKD1_k127_7019209_40 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000008306 276.0
HKD1_k127_7019209_41 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001394 274.0
HKD1_k127_7019209_42 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000842 261.0
HKD1_k127_7019209_43 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000004671 254.0
HKD1_k127_7019209_44 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000003416 250.0
HKD1_k127_7019209_45 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000001312 232.0
HKD1_k127_7019209_46 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000002026 241.0
HKD1_k127_7019209_47 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000004084 232.0
HKD1_k127_7019209_48 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
HKD1_k127_7019209_49 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000003195 218.0
HKD1_k127_7019209_5 Heat shock 70 kDa protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 584.0
HKD1_k127_7019209_50 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000001174 217.0
HKD1_k127_7019209_51 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000001498 218.0
HKD1_k127_7019209_52 - - - - 0.000000000000000000000000000000000000000000000000000000002321 216.0
HKD1_k127_7019209_53 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000279 208.0
HKD1_k127_7019209_54 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000005053 197.0
HKD1_k127_7019209_55 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000005469 204.0
HKD1_k127_7019209_56 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000000000000000000003478 194.0
HKD1_k127_7019209_57 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000001193 196.0
HKD1_k127_7019209_58 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001458 187.0
HKD1_k127_7019209_59 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000002251 172.0
HKD1_k127_7019209_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 568.0
HKD1_k127_7019209_60 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000007359 164.0
HKD1_k127_7019209_61 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001046 167.0
HKD1_k127_7019209_62 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000003595 168.0
HKD1_k127_7019209_63 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000005441 167.0
HKD1_k127_7019209_64 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000007088 170.0
HKD1_k127_7019209_65 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000002774 165.0
HKD1_k127_7019209_66 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000007855 162.0
HKD1_k127_7019209_67 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000001573 154.0
HKD1_k127_7019209_68 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000004749 154.0
HKD1_k127_7019209_69 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000007573 149.0
HKD1_k127_7019209_7 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 543.0
HKD1_k127_7019209_70 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000007633 147.0
HKD1_k127_7019209_72 Transcriptional regulator - - - 0.00000000000000000000000000000000000001669 149.0
HKD1_k127_7019209_73 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000001939 148.0
HKD1_k127_7019209_74 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000003432 144.0
HKD1_k127_7019209_75 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000006281 142.0
HKD1_k127_7019209_76 Membrane - - - 0.000000000000000000000000000000000328 145.0
HKD1_k127_7019209_77 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000001797 132.0
HKD1_k127_7019209_78 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000005251 133.0
HKD1_k127_7019209_79 PFAM heat shock protein DnaJ K04082 - - 0.000000000000000000000000000000008874 136.0
HKD1_k127_7019209_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 486.0
HKD1_k127_7019209_80 ThiS family K03636 - - 0.0000000000000000000000000000006882 125.0
HKD1_k127_7019209_81 protein maturation K13628 - - 0.000000000000000000000000000008235 122.0
HKD1_k127_7019209_82 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000002126 129.0
HKD1_k127_7019209_83 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000000005669 117.0
HKD1_k127_7019209_84 - - - - 0.0000000000000000000000000008899 123.0
HKD1_k127_7019209_85 - - - - 0.000000000000000000000000007359 122.0
HKD1_k127_7019209_86 Oxidoreductase FAD-binding domain K00523,K05784 - 1.17.1.1 0.0000000000000000000000002604 114.0
HKD1_k127_7019209_87 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000003113 111.0
HKD1_k127_7019209_88 - - - - 0.000000000000000000000003659 107.0
HKD1_k127_7019209_89 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000001569 105.0
HKD1_k127_7019209_9 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 477.0
HKD1_k127_7019209_90 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000005722 106.0
HKD1_k127_7019209_91 ATP synthesis coupled proton transport K02109 - - 0.0000000000000000000002321 102.0
HKD1_k127_7019209_92 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000001977 93.0
HKD1_k127_7019209_93 Frataxin-like domain K06202 - - 0.0000000000000000003408 91.0
HKD1_k127_7019209_94 Protein of unknown function (DUF1778) - - - 0.0000000000000000003999 90.0
HKD1_k127_7019209_95 FeS assembly protein IscX - - - 0.0000000000000000006304 94.0
HKD1_k127_7019209_96 - - - - 0.000000000000000003167 90.0
HKD1_k127_7019209_97 - - - - 0.000000000000000101 93.0
HKD1_k127_7019209_98 DNA-sulfur modification-associated - - - 0.000000000000002621 88.0
HKD1_k127_7019209_99 - - - - 0.00000000000001949 83.0
HKD1_k127_7058930_0 STAS domain K04749 - - 0.000000002789 64.0
HKD1_k127_7058930_1 response to abiotic stimulus - - - 0.00000745 54.0
HKD1_k127_7058930_3 PKD domain - - - 0.0005947 51.0
HKD1_k127_7085490_0 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000009319 250.0
HKD1_k127_7085490_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000001811 179.0
HKD1_k127_7103539_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 5.873e-273 860.0
HKD1_k127_7103539_1 Protein of unknown function DUF116 - - - 5.557e-215 683.0
HKD1_k127_7103539_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 349.0
HKD1_k127_7103539_11 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 358.0
HKD1_k127_7103539_12 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 340.0
HKD1_k127_7103539_13 COG1853 Conserved protein domain typically associated with - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 291.0
HKD1_k127_7103539_14 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001873 285.0
HKD1_k127_7103539_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006265 300.0
HKD1_k127_7103539_16 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004153 278.0
HKD1_k127_7103539_17 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 260.0
HKD1_k127_7103539_18 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001436 261.0
HKD1_k127_7103539_19 (2Fe-2S) binding domain protein K07302,K18029 - 1.17.2.1,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000002766 239.0
HKD1_k127_7103539_2 Histidine kinase K20971,K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 597.0
HKD1_k127_7103539_20 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
HKD1_k127_7103539_21 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.00000000000000000000000000000000000000000000000000000001925 211.0
HKD1_k127_7103539_22 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000000000000000000000000001175 201.0
HKD1_k127_7103539_23 oligopeptide transporter - - - 0.000000000000000000000000000000000000005935 152.0
HKD1_k127_7103539_24 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000002319 149.0
HKD1_k127_7103539_25 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000002615 143.0
HKD1_k127_7103539_26 glucose sorbosone - - - 0.000000000000000000000000000000004021 140.0
HKD1_k127_7103539_27 - - - - 0.000000000000000000000000000000009361 143.0
HKD1_k127_7103539_28 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000004164 139.0
HKD1_k127_7103539_29 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000004675 132.0
HKD1_k127_7103539_3 Squalene-hopene cyclase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 580.0
HKD1_k127_7103539_30 - - - - 0.000000000000000000000001531 109.0
HKD1_k127_7103539_32 beta-subunit of geranylgeranyltransferase or farnesyltransferase K05956 - 2.5.1.60 0.0000000000000000000005071 108.0
HKD1_k127_7103539_33 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000002117 100.0
HKD1_k127_7103539_34 Transcriptional regulator K06921 - - 0.000000000000000000009139 100.0
HKD1_k127_7103539_36 - - - - 0.0000000000000001401 91.0
HKD1_k127_7103539_37 Transcriptional regulatory protein, C terminal - - - 0.00000000000009527 81.0
HKD1_k127_7103539_38 - - - - 0.0000001878 61.0
HKD1_k127_7103539_39 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000001305 57.0
HKD1_k127_7103539_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 517.0
HKD1_k127_7103539_40 von Willebrand factor, type A K07114 - - 0.00008336 54.0
HKD1_k127_7103539_5 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 466.0
HKD1_k127_7103539_6 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 430.0
HKD1_k127_7103539_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 407.0
HKD1_k127_7103539_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 408.0
HKD1_k127_7103539_9 SRP54-type protein, GTPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 400.0
HKD1_k127_7167895_0 Dehydrogenase K00117 - 1.1.5.2 1.857e-289 902.0
HKD1_k127_7167895_1 - - - - 1.461e-288 901.0
HKD1_k127_7167895_10 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 542.0
HKD1_k127_7167895_11 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 526.0
HKD1_k127_7167895_12 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HKD1_k127_7167895_13 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 460.0
HKD1_k127_7167895_14 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 444.0
HKD1_k127_7167895_15 Epoxide hydrolase N terminus K21159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 438.0
HKD1_k127_7167895_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 435.0
HKD1_k127_7167895_17 transporter K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 417.0
HKD1_k127_7167895_18 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 406.0
HKD1_k127_7167895_19 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 381.0
HKD1_k127_7167895_2 Dehydrogenase K00117 - 1.1.5.2 6.082e-277 871.0
HKD1_k127_7167895_20 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 376.0
HKD1_k127_7167895_21 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 362.0
HKD1_k127_7167895_22 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
HKD1_k127_7167895_23 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 355.0
HKD1_k127_7167895_24 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 355.0
HKD1_k127_7167895_25 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 332.0
HKD1_k127_7167895_26 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 330.0
HKD1_k127_7167895_27 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 330.0
HKD1_k127_7167895_28 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 321.0
HKD1_k127_7167895_29 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 315.0
HKD1_k127_7167895_3 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 1.545e-225 708.0
HKD1_k127_7167895_30 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 314.0
HKD1_k127_7167895_31 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 314.0
HKD1_k127_7167895_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 299.0
HKD1_k127_7167895_33 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 306.0
HKD1_k127_7167895_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 289.0
HKD1_k127_7167895_35 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001903 296.0
HKD1_k127_7167895_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004015 287.0
HKD1_k127_7167895_37 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003207 274.0
HKD1_k127_7167895_38 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001851 274.0
HKD1_k127_7167895_39 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004606 266.0
HKD1_k127_7167895_4 Protein kinase domain K12132 - 2.7.11.1 2.547e-212 689.0
HKD1_k127_7167895_40 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006429 261.0
HKD1_k127_7167895_41 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003354 249.0
HKD1_k127_7167895_42 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001136 246.0
HKD1_k127_7167895_43 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002871 236.0
HKD1_k127_7167895_44 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008974 245.0
HKD1_k127_7167895_45 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000003466 233.0
HKD1_k127_7167895_46 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD1_k127_7167895_47 - - - - 0.0000000000000000000000000000000000000000000000000000001677 207.0
HKD1_k127_7167895_48 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000005668 205.0
HKD1_k127_7167895_49 - - - - 0.00000000000000000000000000000000000000000000000000005255 199.0
HKD1_k127_7167895_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.453e-205 649.0
HKD1_k127_7167895_50 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000005048 195.0
HKD1_k127_7167895_51 - - - - 0.000000000000000000000000000000000000000000000009082 188.0
HKD1_k127_7167895_52 - - - - 0.00000000000000000000000000000000000000000000001163 186.0
HKD1_k127_7167895_53 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000003577 171.0
HKD1_k127_7167895_54 - - - - 0.000000000000000000000000000000000000000000006119 167.0
HKD1_k127_7167895_55 - - - - 0.00000000000000000000000000000000000000000001108 166.0
HKD1_k127_7167895_56 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000001414 169.0
HKD1_k127_7167895_57 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000002084 164.0
HKD1_k127_7167895_58 Fumarase C-terminus K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000002161 168.0
HKD1_k127_7167895_59 PIN domain - - - 0.00000000000000000000000000000000000000000009747 165.0
HKD1_k127_7167895_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 5.639e-204 643.0
HKD1_k127_7167895_60 - - - - 0.00000000000000000000000000000000000000001296 168.0
HKD1_k127_7167895_61 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000002808 158.0
HKD1_k127_7167895_62 - - - - 0.000000000000000000000000000000000000001185 160.0
HKD1_k127_7167895_63 - - - - 0.000000000000000000000000000000000000001418 151.0
HKD1_k127_7167895_64 Cytochrome c - - - 0.0000000000000000000000000000000000001001 151.0
HKD1_k127_7167895_65 - - - - 0.0000000000000000000000000000000000002909 156.0
HKD1_k127_7167895_66 - - - - 0.0000000000000000000000000000000000003139 154.0
HKD1_k127_7167895_67 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000003393 159.0
HKD1_k127_7167895_68 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000001272 146.0
HKD1_k127_7167895_69 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000016 153.0
HKD1_k127_7167895_7 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 574.0
HKD1_k127_7167895_70 - - - - 0.0000000000000000000000000000000006117 137.0
HKD1_k127_7167895_71 - - - - 0.00000000000000000000000000000009764 139.0
HKD1_k127_7167895_74 SnoaL-like domain - - - 0.00000000000000000000001288 106.0
HKD1_k127_7167895_75 - - - - 0.000000000000000000001582 102.0
HKD1_k127_7167895_76 GCN5-related N-acetyl-transferase - - - 0.000000000000000001469 90.0
HKD1_k127_7167895_77 beta-propeller repeat - - - 0.000000000000000005855 85.0
HKD1_k127_7167895_78 Cupin 2, conserved barrel domain protein - - - 0.00000000000000008929 89.0
HKD1_k127_7167895_79 Domain of unknown function (DU1801) - - - 0.0000000000000003958 86.0
HKD1_k127_7167895_8 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 571.0
HKD1_k127_7167895_80 beta-propeller repeat - - - 0.000000000000003214 79.0
HKD1_k127_7167895_81 tRNA wobble adenosine to inosine editing - - - 0.000000000000122 77.0
HKD1_k127_7167895_82 Hsp20/alpha crystallin family - - - 0.000000000004788 72.0
HKD1_k127_7167895_84 Transposase - - - 0.00000004563 59.0
HKD1_k127_7167895_85 - - - - 0.0000001022 59.0
HKD1_k127_7167895_86 Ankyrin repeat - - - 0.000004644 58.0
HKD1_k127_7167895_87 lactoylglutathione lyase activity - - - 0.00001459 53.0
HKD1_k127_7167895_88 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00003376 53.0
HKD1_k127_7167895_89 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0005086 52.0
HKD1_k127_7167895_9 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 559.0
HKD1_k127_7187156_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.486e-240 744.0
HKD1_k127_7263512_0 Protein of unknown function (DUF3363) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
HKD1_k127_7263512_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000002932 205.0
HKD1_k127_7263512_2 COG3328 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000004004 205.0
HKD1_k127_7263512_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000004588 57.0
HKD1_k127_7381282_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1242.0
HKD1_k127_7381282_1 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.0 1091.0
HKD1_k127_7381282_10 Inorganic ion transport and metabolism K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 471.0
HKD1_k127_7381282_11 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 480.0
HKD1_k127_7381282_12 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 432.0
HKD1_k127_7381282_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 428.0
HKD1_k127_7381282_14 TIGRFAM polyphosphate kinase 2, PA0141 family K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 393.0
HKD1_k127_7381282_15 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 394.0
HKD1_k127_7381282_16 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 373.0
HKD1_k127_7381282_17 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 364.0
HKD1_k127_7381282_18 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 363.0
HKD1_k127_7381282_19 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 351.0
HKD1_k127_7381282_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1011.0
HKD1_k127_7381282_20 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 339.0
HKD1_k127_7381282_21 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HKD1_k127_7381282_22 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
HKD1_k127_7381282_23 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000676 255.0
HKD1_k127_7381282_24 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000009498 210.0
HKD1_k127_7381282_25 VIT family - - - 0.00000000000000000000000000000000000000000000007438 179.0
HKD1_k127_7381282_26 universal stress protein - - - 0.00000000000000000000000000000000002701 146.0
HKD1_k127_7381282_27 Pfam Activator of Hsp90 ATPase - - - 0.000000000000000000000006246 107.0
HKD1_k127_7381282_28 - - - - 0.00000000000000000000007622 109.0
HKD1_k127_7381282_29 Molybdopterin oxidoreductase - - - 0.0000000000002612 71.0
HKD1_k127_7381282_3 serine dehydratase beta chain K01752 - 4.3.1.17 5.763e-236 745.0
HKD1_k127_7381282_30 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000003516 73.0
HKD1_k127_7381282_31 Domain of unknown function (DUF4136) - - - 0.00000001176 66.0
HKD1_k127_7381282_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.225e-226 713.0
HKD1_k127_7381282_5 Sulfate permease family - - - 2.773e-198 632.0
HKD1_k127_7381282_6 6-phosphofructokinase activity K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 582.0
HKD1_k127_7381282_7 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 507.0
HKD1_k127_7381282_8 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 514.0
HKD1_k127_7381282_9 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 490.0
HKD1_k127_7435976_0 PFAM alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001756 229.0
HKD1_k127_7435976_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000002273 95.0
HKD1_k127_7450180_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.658e-317 983.0
HKD1_k127_7450180_1 Spermine/spermidine synthase domain - - - 1.081e-267 845.0
HKD1_k127_7450180_10 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 375.0
HKD1_k127_7450180_11 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 336.0
HKD1_k127_7450180_12 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 321.0
HKD1_k127_7450180_13 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 297.0
HKD1_k127_7450180_14 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 287.0
HKD1_k127_7450180_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 286.0
HKD1_k127_7450180_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002383 284.0
HKD1_k127_7450180_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 263.0
HKD1_k127_7450180_18 Clostripain family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001543 273.0
HKD1_k127_7450180_19 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001698 271.0
HKD1_k127_7450180_2 elongation factor G K02355 - - 3.074e-206 662.0
HKD1_k127_7450180_20 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001869 271.0
HKD1_k127_7450180_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001493 248.0
HKD1_k127_7450180_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000864 261.0
HKD1_k127_7450180_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009902 255.0
HKD1_k127_7450180_24 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000005618 232.0
HKD1_k127_7450180_25 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000001781 226.0
HKD1_k127_7450180_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000134 224.0
HKD1_k127_7450180_27 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
HKD1_k127_7450180_28 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000004003 217.0
HKD1_k127_7450180_29 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000579 218.0
HKD1_k127_7450180_3 Cystathionine beta-synthase K01697 - 4.2.1.22 6.55e-199 629.0
HKD1_k127_7450180_30 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000008755 219.0
HKD1_k127_7450180_31 - - - - 0.00000000000000000000000000000000000000000000000000000006208 201.0
HKD1_k127_7450180_32 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000001975 203.0
HKD1_k127_7450180_33 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000001042 193.0
HKD1_k127_7450180_34 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000001814 190.0
HKD1_k127_7450180_35 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
HKD1_k127_7450180_36 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000009208 194.0
HKD1_k127_7450180_37 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000008197 177.0
HKD1_k127_7450180_38 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000001588 162.0
HKD1_k127_7450180_39 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000002632 161.0
HKD1_k127_7450180_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 602.0
HKD1_k127_7450180_40 - - - - 0.000000000000000000000000000000000000000003053 160.0
HKD1_k127_7450180_41 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003574 162.0
HKD1_k127_7450180_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000005581 154.0
HKD1_k127_7450180_43 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000001648 160.0
HKD1_k127_7450180_44 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000008727 136.0
HKD1_k127_7450180_45 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000001254 135.0
HKD1_k127_7450180_46 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000158 138.0
HKD1_k127_7450180_47 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000002769 133.0
HKD1_k127_7450180_48 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000003873 134.0
HKD1_k127_7450180_49 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000006079 130.0
HKD1_k127_7450180_5 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 522.0
HKD1_k127_7450180_50 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000002368 126.0
HKD1_k127_7450180_51 Protein of unknown function (DUF1353) - - - 0.00000000000000000000000003066 115.0
HKD1_k127_7450180_52 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000004659 115.0
HKD1_k127_7450180_53 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001133 111.0
HKD1_k127_7450180_54 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000522 114.0
HKD1_k127_7450180_55 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000003315 109.0
HKD1_k127_7450180_56 YCII-related domain K09780 - - 0.000000000000000000000004 119.0
HKD1_k127_7450180_57 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000004688 100.0
HKD1_k127_7450180_58 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000005725 105.0
HKD1_k127_7450180_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 467.0
HKD1_k127_7450180_60 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000002201 93.0
HKD1_k127_7450180_61 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000001108 95.0
HKD1_k127_7450180_62 nucleotidyltransferase activity - - - 0.00000000000000002006 87.0
HKD1_k127_7450180_64 - - - - 0.00000000000001914 79.0
HKD1_k127_7450180_65 Ribosomal protein L30 K02907 - - 0.00000000000002053 74.0
HKD1_k127_7450180_66 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000007684 73.0
HKD1_k127_7450180_67 Protein of unknown function (DUF2834) - - - 0.0000000000242 72.0
HKD1_k127_7450180_68 YCII-related domain - - - 0.0000000008558 61.0
HKD1_k127_7450180_69 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000006298 67.0
HKD1_k127_7450180_7 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 414.0
HKD1_k127_7450180_70 Protein of unknown function (DUF2834) - - - 0.00000001092 58.0
HKD1_k127_7450180_71 Protein conserved in bacteria K15539 - - 0.00000002368 61.0
HKD1_k127_7450180_72 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000001143 58.0
HKD1_k127_7450180_73 integral membrane protein - - - 0.000002219 50.0
HKD1_k127_7450180_74 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC K09667 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.255 0.000006948 58.0
HKD1_k127_7450180_75 long-chain fatty acid transport protein - - - 0.0003775 52.0
HKD1_k127_7450180_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 400.0
HKD1_k127_7450180_9 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 408.0
HKD1_k127_7495741_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1233.0
HKD1_k127_7495741_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000001953 154.0
HKD1_k127_7608225_0 helicase activity - - - 1.191e-276 872.0
HKD1_k127_7608225_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.812e-238 765.0
HKD1_k127_7608225_10 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 497.0
HKD1_k127_7608225_11 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 489.0
HKD1_k127_7608225_12 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 501.0
HKD1_k127_7608225_13 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 468.0
HKD1_k127_7608225_14 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 442.0
HKD1_k127_7608225_15 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 440.0
HKD1_k127_7608225_16 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 429.0
HKD1_k127_7608225_17 - K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 407.0
HKD1_k127_7608225_18 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 404.0
HKD1_k127_7608225_19 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 402.0
HKD1_k127_7608225_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.848e-236 741.0
HKD1_k127_7608225_20 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HKD1_k127_7608225_21 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
HKD1_k127_7608225_22 DNA modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 344.0
HKD1_k127_7608225_23 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
HKD1_k127_7608225_24 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002998 283.0
HKD1_k127_7608225_25 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008811 269.0
HKD1_k127_7608225_26 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000001775 278.0
HKD1_k127_7608225_27 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
HKD1_k127_7608225_28 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000008845 235.0
HKD1_k127_7608225_29 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000007982 234.0
HKD1_k127_7608225_3 PFAM Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 610.0
HKD1_k127_7608225_30 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000003839 229.0
HKD1_k127_7608225_31 PFAM helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000005076 238.0
HKD1_k127_7608225_32 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000893 224.0
HKD1_k127_7608225_33 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000001924 211.0
HKD1_k127_7608225_34 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000004729 214.0
HKD1_k127_7608225_35 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000003144 192.0
HKD1_k127_7608225_36 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000001591 192.0
HKD1_k127_7608225_37 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000003843 188.0
HKD1_k127_7608225_38 COGs COG2912 conserved - - - 0.0000000000000000000000000000000000000000000000002678 188.0
HKD1_k127_7608225_39 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000006109 182.0
HKD1_k127_7608225_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 584.0
HKD1_k127_7608225_40 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000007859 187.0
HKD1_k127_7608225_41 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000004825 183.0
HKD1_k127_7608225_42 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000001352 181.0
HKD1_k127_7608225_43 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000005196 179.0
HKD1_k127_7608225_44 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000001124 171.0
HKD1_k127_7608225_45 AAA domain K02282 - - 0.00000000000000000000000000000000000000000008755 176.0
HKD1_k127_7608225_46 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000004445 160.0
HKD1_k127_7608225_47 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000009977 163.0
HKD1_k127_7608225_48 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000005083 171.0
HKD1_k127_7608225_49 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000001911 137.0
HKD1_k127_7608225_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 582.0
HKD1_k127_7608225_50 BMC - - - 0.00000000000000000000000000000004243 128.0
HKD1_k127_7608225_51 - - - - 0.00000000000000000000000000000008905 139.0
HKD1_k127_7608225_52 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000001171 133.0
HKD1_k127_7608225_53 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000007405 115.0
HKD1_k127_7608225_54 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000003411 127.0
HKD1_k127_7608225_55 PFAM amine oxidase - - - 0.000000000000000000000000002029 120.0
HKD1_k127_7608225_56 - - - - 0.000000000000000000000000005858 113.0
HKD1_k127_7608225_57 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000001941 117.0
HKD1_k127_7608225_58 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000005885 107.0
HKD1_k127_7608225_59 Acetyltransferase (GNAT) family - - - 0.00000000000000000000006319 106.0
HKD1_k127_7608225_6 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 557.0
HKD1_k127_7608225_60 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000003089 106.0
HKD1_k127_7608225_61 regulation of translation K03530 - - 0.00000000000000000003794 93.0
HKD1_k127_7608225_62 - - - - 0.0000000000000000001231 93.0
HKD1_k127_7608225_63 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000002217 93.0
HKD1_k127_7608225_64 hyperosmotic response - - - 0.00000000000000004481 93.0
HKD1_k127_7608225_65 helix_turn_helix, mercury resistance - - - 0.00000000000003446 78.0
HKD1_k127_7608225_66 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000001606 81.0
HKD1_k127_7608225_67 Smr domain - - - 0.000000000001081 79.0
HKD1_k127_7608225_68 Protein of unknown function (DUF2662) - - - 0.000000000001157 74.0
HKD1_k127_7608225_69 Tyrosine phosphatase family - - - 0.000002674 58.0
HKD1_k127_7608225_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 566.0
HKD1_k127_7608225_70 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.0000122 48.0
HKD1_k127_7608225_71 Sh3 type 3 domain protein - - - 0.00003652 56.0
HKD1_k127_7608225_72 Protein of unknown function (DUF1634) - - - 0.0001514 48.0
HKD1_k127_7608225_73 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0001778 53.0
HKD1_k127_7608225_8 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 541.0
HKD1_k127_7608225_9 Isocitrate/isopropylmalate dehydrogenase K07246 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006108,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009027,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 505.0
HKD1_k127_7689372_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1368.0
HKD1_k127_7689372_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 9.45e-302 946.0
HKD1_k127_7689372_10 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 447.0
HKD1_k127_7689372_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 436.0
HKD1_k127_7689372_12 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 413.0
HKD1_k127_7689372_13 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 414.0
HKD1_k127_7689372_14 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 404.0
HKD1_k127_7689372_15 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 355.0
HKD1_k127_7689372_16 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
HKD1_k127_7689372_17 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 325.0
HKD1_k127_7689372_18 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 318.0
HKD1_k127_7689372_19 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 310.0
HKD1_k127_7689372_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.489e-247 790.0
HKD1_k127_7689372_20 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
HKD1_k127_7689372_21 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 308.0
HKD1_k127_7689372_22 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 314.0
HKD1_k127_7689372_23 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 301.0
HKD1_k127_7689372_24 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
HKD1_k127_7689372_25 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 290.0
HKD1_k127_7689372_26 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 301.0
HKD1_k127_7689372_27 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001686 293.0
HKD1_k127_7689372_28 phosphorylase kinase alphabeta K07190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 289.0
HKD1_k127_7689372_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006672 276.0
HKD1_k127_7689372_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 573.0
HKD1_k127_7689372_30 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002093 272.0
HKD1_k127_7689372_31 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000003959 271.0
HKD1_k127_7689372_32 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 278.0
HKD1_k127_7689372_33 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000001757 255.0
HKD1_k127_7689372_34 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000001544 253.0
HKD1_k127_7689372_35 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000001766 250.0
HKD1_k127_7689372_36 MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002235 241.0
HKD1_k127_7689372_37 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
HKD1_k127_7689372_38 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000001253 232.0
HKD1_k127_7689372_39 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000006175 214.0
HKD1_k127_7689372_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 523.0
HKD1_k127_7689372_40 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000003586 194.0
HKD1_k127_7689372_41 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000547 199.0
HKD1_k127_7689372_42 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000009857 205.0
HKD1_k127_7689372_43 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000002835 199.0
HKD1_k127_7689372_44 Putative ABC exporter - - - 0.000000000000000000000000000000000000000000000002466 194.0
HKD1_k127_7689372_45 - - - - 0.000000000000000000000000000000000000000000000506 180.0
HKD1_k127_7689372_46 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000001905 183.0
HKD1_k127_7689372_47 - - - - 0.0000000000000000000000000000000000000000001175 164.0
HKD1_k127_7689372_48 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000002908 164.0
HKD1_k127_7689372_49 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000005197 154.0
HKD1_k127_7689372_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 501.0
HKD1_k127_7689372_50 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000004754 154.0
HKD1_k127_7689372_51 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000741 147.0
HKD1_k127_7689372_52 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000005539 141.0
HKD1_k127_7689372_53 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000002141 115.0
HKD1_k127_7689372_54 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000886 119.0
HKD1_k127_7689372_55 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000009597 111.0
HKD1_k127_7689372_56 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000002451 113.0
HKD1_k127_7689372_57 Ribosomal L32p protein family K02911 - - 0.0000000000000000000000016 103.0
HKD1_k127_7689372_58 Lipopolysaccharide-assembly - - - 0.00000000000000000000002561 108.0
HKD1_k127_7689372_59 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000441 109.0
HKD1_k127_7689372_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 510.0
HKD1_k127_7689372_60 Pfam:N_methyl_2 - - - 0.0000000000000000000223 98.0
HKD1_k127_7689372_62 Domain of unknown function (DUF1844) - - - 0.0000000000000000425 83.0
HKD1_k127_7689372_63 TonB C terminal - - - 0.000000000000001653 87.0
HKD1_k127_7689372_64 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000003954 77.0
HKD1_k127_7689372_65 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000004952 84.0
HKD1_k127_7689372_66 PFAM PEGA domain - - - 0.0000000000003262 83.0
HKD1_k127_7689372_67 - - - - 0.0000000000007948 79.0
HKD1_k127_7689372_68 Belongs to the 'phage' integrase family - - - 0.000000000104 68.0
HKD1_k127_7689372_69 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000002257 72.0
HKD1_k127_7689372_7 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 452.0
HKD1_k127_7689372_71 - - - - 0.0000000634 58.0
HKD1_k127_7689372_72 regulation of DNA repair K03565 - - 0.0000003261 59.0
HKD1_k127_7689372_74 Protein of unknown function (DUF1232) - - - 0.000001831 55.0
HKD1_k127_7689372_8 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 445.0
HKD1_k127_7689372_9 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 442.0
HKD1_k127_7745449_0 Belongs to the GcvT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 406.0
HKD1_k127_7745449_1 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0001616 46.0
HKD1_k127_7762838_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1043.0
HKD1_k127_7762838_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 7.882e-270 843.0
HKD1_k127_7762838_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 434.0
HKD1_k127_7762838_3 PhoQ Sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 349.0
HKD1_k127_7762838_4 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 339.0
HKD1_k127_7762838_5 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 312.0
HKD1_k127_7762838_6 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000002109 250.0
HKD1_k127_7762838_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000002429 214.0
HKD1_k127_7762838_8 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000001034 206.0
HKD1_k127_7762838_9 - - - - 0.00002442 53.0
HKD1_k127_7768216_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1116.0
HKD1_k127_7768216_1 PFAM Type II secretion system protein E K02652 - - 1.187e-225 713.0
HKD1_k127_7768216_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 362.0
HKD1_k127_7768216_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 346.0
HKD1_k127_7768216_12 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 333.0
HKD1_k127_7768216_13 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 333.0
HKD1_k127_7768216_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 296.0
HKD1_k127_7768216_15 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 309.0
HKD1_k127_7768216_16 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004602 287.0
HKD1_k127_7768216_17 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
HKD1_k127_7768216_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000002788 249.0
HKD1_k127_7768216_19 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002202 244.0
HKD1_k127_7768216_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 600.0
HKD1_k127_7768216_20 BON domain K04065 - - 0.00000000000000000000000000000000000000000000000000000000000000001476 230.0
HKD1_k127_7768216_21 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002282 245.0
HKD1_k127_7768216_22 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
HKD1_k127_7768216_23 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000006503 220.0
HKD1_k127_7768216_24 - - - - 0.000000000000000000000000000000000000000000000000000000001314 208.0
HKD1_k127_7768216_25 PFAM Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000001163 201.0
HKD1_k127_7768216_26 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000000000000009484 186.0
HKD1_k127_7768216_27 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000002667 197.0
HKD1_k127_7768216_28 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000002238 183.0
HKD1_k127_7768216_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000002698 172.0
HKD1_k127_7768216_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 602.0
HKD1_k127_7768216_30 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000002652 170.0
HKD1_k127_7768216_31 - - - - 0.000000000000000000000000000000000000007175 154.0
HKD1_k127_7768216_32 PFAM microcompartments protein K04027 - - 0.000000000000000000000000000000000000007839 147.0
HKD1_k127_7768216_33 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000007324 154.0
HKD1_k127_7768216_34 Transglycosylase SLT domain - - - 0.000000000000000000000000000000006287 137.0
HKD1_k127_7768216_35 MacB-like periplasmic core domain - - - 0.000000000000000000000000000003378 135.0
HKD1_k127_7768216_36 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000002482 108.0
HKD1_k127_7768216_37 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000316 108.0
HKD1_k127_7768216_38 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000001103 104.0
HKD1_k127_7768216_39 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000006929 90.0
HKD1_k127_7768216_4 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 579.0
HKD1_k127_7768216_40 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000006217 85.0
HKD1_k127_7768216_41 PFAM UspA domain protein K06149 - - 0.000000000000002874 87.0
HKD1_k127_7768216_42 - - - - 0.000000000000003558 88.0
HKD1_k127_7768216_43 - - - - 0.0000000005468 67.0
HKD1_k127_7768216_44 Pilus assembly protein K02662 - - 0.000000002933 68.0
HKD1_k127_7768216_45 deoxyhypusine monooxygenase activity - - - 0.000000003614 63.0
HKD1_k127_7768216_46 PFAM Fimbrial assembly family protein K02663 - - 0.00000002454 66.0
HKD1_k127_7768216_47 - - - - 0.00003493 50.0
HKD1_k127_7768216_48 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001443 53.0
HKD1_k127_7768216_49 Beta-L-arabinofuranosidase, GH127 - - - 0.0005261 52.0
HKD1_k127_7768216_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 571.0
HKD1_k127_7768216_6 Magnesium chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 513.0
HKD1_k127_7768216_7 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 505.0
HKD1_k127_7768216_8 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 475.0
HKD1_k127_7768216_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 413.0
HKD1_k127_7784908_0 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 6.056e-198 635.0
HKD1_k127_7784908_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 592.0
HKD1_k127_7784908_10 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 316.0
HKD1_k127_7784908_11 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 271.0
HKD1_k127_7784908_12 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 266.0
HKD1_k127_7784908_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000009473 219.0
HKD1_k127_7784908_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000004036 189.0
HKD1_k127_7784908_15 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000003268 174.0
HKD1_k127_7784908_16 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000002994 105.0
HKD1_k127_7784908_17 Protein of unknown function (DUF3617) - - - 0.00000000000000000005992 105.0
HKD1_k127_7784908_18 Methyltransferase FkbM domain - - - 0.000000001416 68.0
HKD1_k127_7784908_2 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 552.0
HKD1_k127_7784908_20 - - - - 0.00000003798 66.0
HKD1_k127_7784908_3 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 541.0
HKD1_k127_7784908_4 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 522.0
HKD1_k127_7784908_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 482.0
HKD1_k127_7784908_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 436.0
HKD1_k127_7784908_7 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 428.0
HKD1_k127_7784908_8 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 428.0
HKD1_k127_7784908_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 424.0
HKD1_k127_7842148_0 - - - - 5.558e-214 684.0
HKD1_k127_7842148_1 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 6.399e-206 656.0
HKD1_k127_7842148_10 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 314.0
HKD1_k127_7842148_11 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 308.0
HKD1_k127_7842148_12 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 299.0
HKD1_k127_7842148_13 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002483 287.0
HKD1_k127_7842148_14 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
HKD1_k127_7842148_15 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001063 260.0
HKD1_k127_7842148_16 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
HKD1_k127_7842148_17 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000001035 220.0
HKD1_k127_7842148_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000002405 216.0
HKD1_k127_7842148_19 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000002742 223.0
HKD1_k127_7842148_2 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 534.0
HKD1_k127_7842148_20 Cytidylate kinase-like family K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000232 203.0
HKD1_k127_7842148_21 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000000000000002899 197.0
HKD1_k127_7842148_22 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000003195 196.0
HKD1_k127_7842148_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000001797 190.0
HKD1_k127_7842148_24 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000002136 178.0
HKD1_k127_7842148_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000003594 174.0
HKD1_k127_7842148_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000002632 168.0
HKD1_k127_7842148_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000001573 138.0
HKD1_k127_7842148_28 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000008493 133.0
HKD1_k127_7842148_29 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000003708 119.0
HKD1_k127_7842148_3 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 503.0
HKD1_k127_7842148_30 oxidoreductase activity - - - 0.000000000000000000000000004729 128.0
HKD1_k127_7842148_31 - - - - 0.000000000000000005735 94.0
HKD1_k127_7842148_32 Cold shock protein domain - - - 0.000000000000003766 78.0
HKD1_k127_7842148_33 oxidoreductase activity - - - 0.000000006262 69.0
HKD1_k127_7842148_34 N-methylation of lysine residues in flagellin K00599 K18475 - - 0.000003555 59.0
HKD1_k127_7842148_35 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00005652 54.0
HKD1_k127_7842148_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 501.0
HKD1_k127_7842148_5 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 450.0
HKD1_k127_7842148_6 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 447.0
HKD1_k127_7842148_7 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 371.0
HKD1_k127_7842148_8 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 334.0
HKD1_k127_7842148_9 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 331.0
HKD1_k127_7913082_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1074.0
HKD1_k127_7913082_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.836e-291 906.0
HKD1_k127_7913082_10 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000002086 212.0
HKD1_k127_7913082_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000267 172.0
HKD1_k127_7913082_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000007132 143.0
HKD1_k127_7913082_13 von Willebrand factor, type A - - - 0.000000000009349 72.0
HKD1_k127_7913082_14 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0005006 52.0
HKD1_k127_7913082_2 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 536.0
HKD1_k127_7913082_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 442.0
HKD1_k127_7913082_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 434.0
HKD1_k127_7913082_5 PFAM Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
HKD1_k127_7913082_6 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 306.0
HKD1_k127_7913082_7 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000003271 278.0
HKD1_k127_7913082_8 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009273 253.0
HKD1_k127_7913082_9 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000007183 237.0
HKD1_k127_7926607_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 3.233e-254 795.0
HKD1_k127_7926607_1 Amino acid permease - - - 3.05e-246 781.0
HKD1_k127_7926607_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 380.0
HKD1_k127_7926607_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 372.0
HKD1_k127_7926607_12 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 366.0
HKD1_k127_7926607_13 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 344.0
HKD1_k127_7926607_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 328.0
HKD1_k127_7926607_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 296.0
HKD1_k127_7926607_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000008665 273.0
HKD1_k127_7926607_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000007791 254.0
HKD1_k127_7926607_18 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000001643 224.0
HKD1_k127_7926607_19 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000001298 215.0
HKD1_k127_7926607_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 571.0
HKD1_k127_7926607_20 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000002075 223.0
HKD1_k127_7926607_21 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000009251 188.0
HKD1_k127_7926607_22 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000003449 184.0
HKD1_k127_7926607_23 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000001671 174.0
HKD1_k127_7926607_24 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000004547 170.0
HKD1_k127_7926607_25 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000002288 158.0
HKD1_k127_7926607_26 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000002633 156.0
HKD1_k127_7926607_27 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000009637 156.0
HKD1_k127_7926607_28 transferase activity, transferring glycosyl groups K00786 - - 0.000000000000000000000000000000001056 143.0
HKD1_k127_7926607_29 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000001471 132.0
HKD1_k127_7926607_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 580.0
HKD1_k127_7926607_30 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000006909 126.0
HKD1_k127_7926607_31 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000284 132.0
HKD1_k127_7926607_32 - - - - 0.0000000000000000000002095 101.0
HKD1_k127_7926607_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000001684 109.0
HKD1_k127_7926607_34 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000007036 105.0
HKD1_k127_7926607_35 regulatory protein, MerR - - - 0.000000000000000722 86.0
HKD1_k127_7926607_36 methyltransferase - - - 0.0000000000002508 78.0
HKD1_k127_7926607_37 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000114 72.0
HKD1_k127_7926607_38 S-layer homology domain - - - 0.00001505 57.0
HKD1_k127_7926607_39 Phage integrase, N-terminal SAM-like domain - - - 0.00002937 50.0
HKD1_k127_7926607_4 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 494.0
HKD1_k127_7926607_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 497.0
HKD1_k127_7926607_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 473.0
HKD1_k127_7926607_7 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 434.0
HKD1_k127_7926607_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 421.0
HKD1_k127_7926607_9 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 389.0
HKD1_k127_7954372_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1076.0
HKD1_k127_7954372_1 Heat shock 70 kDa protein K04043 - - 1.694e-300 932.0
HKD1_k127_7954372_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 321.0
HKD1_k127_7954372_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
HKD1_k127_7954372_12 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008283 281.0
HKD1_k127_7954372_13 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000006151 268.0
HKD1_k127_7954372_14 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000007555 203.0
HKD1_k127_7954372_15 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000004357 200.0
HKD1_k127_7954372_16 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000001663 192.0
HKD1_k127_7954372_17 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000001745 175.0
HKD1_k127_7954372_18 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000779 162.0
HKD1_k127_7954372_19 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000009346 148.0
HKD1_k127_7954372_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.187e-220 694.0
HKD1_k127_7954372_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000001059 135.0
HKD1_k127_7954372_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000002131 121.0
HKD1_k127_7954372_22 response regulator - - - 0.00000000000000000000129 107.0
HKD1_k127_7954372_23 outer membrane autotransporter barrel domain protein - - - 0.00000005403 64.0
HKD1_k127_7954372_24 Sporulation related domain K03749 - - 0.00001851 55.0
HKD1_k127_7954372_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 601.0
HKD1_k127_7954372_4 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 591.0
HKD1_k127_7954372_5 MviN-like protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 565.0
HKD1_k127_7954372_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 413.0
HKD1_k127_7954372_7 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 363.0
HKD1_k127_7954372_8 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 361.0
HKD1_k127_7954372_9 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 337.0
HKD1_k127_7984966_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003364 259.0
HKD1_k127_7984966_1 Serine aminopeptidase, S33 K07019 - - 0.00000000000002105 76.0
HKD1_k127_7984966_2 RNA recognition motif - - - 0.0000000000000859 74.0
HKD1_k127_879109_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 399.0
HKD1_k127_879109_1 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 372.0
HKD1_k127_879109_2 histidine kinase, HAMP K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 314.0
HKD1_k127_879109_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
HKD1_k127_879109_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000008467 143.0
HKD1_k127_879109_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001458 124.0
HKD1_k127_879109_6 Bacterial regulatory protein, Fis family - - - 0.0000000347 58.0
HKD1_k127_885496_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000007381 120.0
HKD1_k127_885496_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000001598 73.0
HKD1_k127_885496_2 SEC-C Motif Domain Protein - - - 0.0000003758 55.0
HKD1_k127_885496_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00002013 57.0
HKD1_k127_885496_4 SOS response associated peptidase (SRAP) - - - 0.0001243 51.0
HKD1_k127_938741_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1349.0
HKD1_k127_938741_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 438.0
HKD1_k127_938741_10 PEGA domain - - - 0.000000000000000000001504 109.0
HKD1_k127_938741_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000002712 92.0
HKD1_k127_938741_12 O-linked GlcNAc transferase - - - 0.000000000000001629 89.0
HKD1_k127_938741_13 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000006477 77.0
HKD1_k127_938741_14 Protein of unknown function (DUF3108) - - - 0.000000000000576 78.0
HKD1_k127_938741_2 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 415.0
HKD1_k127_938741_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 367.0
HKD1_k127_938741_4 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 356.0
HKD1_k127_938741_5 PFAM FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006472 276.0
HKD1_k127_938741_6 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000308 230.0
HKD1_k127_938741_7 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000008016 210.0
HKD1_k127_938741_8 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000009512 152.0
HKD1_k127_938741_9 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00000000000000000000000000000004271 138.0
HKD1_k127_973597_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
HKD1_k127_973597_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000006874 217.0
HKD1_k127_973597_2 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000009778 138.0
HKD1_k127_980900_0 - - - - 0.00000000000000000000000000000000000000000000000000000341 204.0
HKD1_k127_980900_1 - - - - 0.0000000000000000000000000000000000000000000001916 184.0
HKD1_k127_980900_2 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000001413 137.0
HKD1_k127_980900_3 DinB superfamily - - - 0.0000000000000003895 85.0
HKD1_k127_980900_4 Cold shock protein domain - - - 0.0000000000003259 71.0
HKD1_k127_980900_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000005461 53.0
HKD1_k127_980900_6 Serine phosphatase RsbU, regulator of sigma subunit K07315 - 3.1.3.3 0.00004089 48.0
HKD1_k127_988707_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 0.0 1149.0
HKD1_k127_988707_1 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.781e-292 921.0
HKD1_k127_988707_10 ABC transporter K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 327.0
HKD1_k127_988707_11 cytochrome K17230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 332.0
HKD1_k127_988707_12 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
HKD1_k127_988707_13 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 316.0
HKD1_k127_988707_14 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 248.0
HKD1_k127_988707_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000095 231.0
HKD1_k127_988707_16 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000004718 149.0
HKD1_k127_988707_17 DinB superfamily - - - 0.0000000000000000000000000000001717 133.0
HKD1_k127_988707_18 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000002602 79.0
HKD1_k127_988707_19 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000005888 79.0
HKD1_k127_988707_2 Protein involved in monooxygenase activity, disulfide oxidoreductase activity and electron transport K07222 - - 4.44e-246 773.0
HKD1_k127_988707_20 Bacterial Ig-like domain 2 - - - 0.000003365 58.0
HKD1_k127_988707_3 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 2.103e-214 685.0
HKD1_k127_988707_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 1.541e-199 640.0
HKD1_k127_988707_5 aminopeptidase activity K05994 - 3.4.11.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 515.0
HKD1_k127_988707_6 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 397.0
HKD1_k127_988707_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 371.0
HKD1_k127_988707_8 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 337.0
HKD1_k127_988707_9 abc transporter atp-binding protein K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 329.0
HKD1_k127_996173_0 Protein export membrane protein K03296,K18138 - - 0.0 1229.0
HKD1_k127_996173_1 - - - - 3.657e-301 939.0
HKD1_k127_996173_10 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 420.0
HKD1_k127_996173_11 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 382.0
HKD1_k127_996173_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 366.0
HKD1_k127_996173_13 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 315.0
HKD1_k127_996173_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 303.0
HKD1_k127_996173_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
HKD1_k127_996173_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 294.0
HKD1_k127_996173_17 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 259.0
HKD1_k127_996173_18 FAD linked oxidases, C-terminal domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000006567 218.0
HKD1_k127_996173_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000008631 175.0
HKD1_k127_996173_2 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 3.843e-201 636.0
HKD1_k127_996173_20 - - - - 0.0000000000000000000000000000000000000001238 163.0
HKD1_k127_996173_21 - - - - 0.000000000000000000000000000000000000006493 151.0
HKD1_k127_996173_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000005671 161.0
HKD1_k127_996173_23 - - - - 0.000000000000000000000000000000004646 133.0
HKD1_k127_996173_24 Cupin - - - 0.00000000000000000000000000000007645 129.0
HKD1_k127_996173_25 - - - - 0.000000000000000000000000002866 118.0
HKD1_k127_996173_26 Methyltransferase domain - - - 0.0000000000000000000000004843 113.0
HKD1_k127_996173_27 - - - - 0.0000000000000000000000475 105.0
HKD1_k127_996173_28 Cysteine-rich domain K11473,K18928 - - 0.0000000000000000002199 92.0
HKD1_k127_996173_29 Cytochrome c - - - 0.000000000000000002001 97.0
HKD1_k127_996173_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 621.0
HKD1_k127_996173_33 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000002186 59.0
HKD1_k127_996173_34 - - - - 0.0000006996 60.0
HKD1_k127_996173_35 nuclear chromosome segregation K03497 - - 0.000002388 63.0
HKD1_k127_996173_36 protein serine/threonine phosphatase activity - - - 0.00001331 56.0
HKD1_k127_996173_37 - - - - 0.00007291 53.0
HKD1_k127_996173_38 Membrane - - - 0.0001709 52.0
HKD1_k127_996173_39 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003164 52.0
HKD1_k127_996173_4 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 611.0
HKD1_k127_996173_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 582.0
HKD1_k127_996173_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 543.0
HKD1_k127_996173_7 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 534.0
HKD1_k127_996173_8 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 485.0
HKD1_k127_996173_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 461.0