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Overview

ID MAG01736
Name HKD1_bin.53
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus JAQBQB01
Species
Assembly information
Completeness (%) 86.32
Contamination (%) 3.42
GC content (%) 67.0
N50 (bp) 29,029
Genome size (bp) 4,574,903

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3737

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1004496_0 Prolyl oligopeptidase family - - - 1.902e-249 800.0
HKD1_k127_1004496_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 558.0
HKD1_k127_1004496_2 Wd-40 repeat - - - 0.0000000000000000000000000000608 130.0
HKD1_k127_1012267_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 325.0
HKD1_k127_1012267_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 310.0
HKD1_k127_1012267_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
HKD1_k127_1012267_3 Methyltransferase domain - - - 0.0000000000000000000000000000001678 130.0
HKD1_k127_1012267_4 cellulose binding - - - 0.00000000000000000000000000000712 130.0
HKD1_k127_1021486_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.759e-256 804.0
HKD1_k127_1021486_1 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 560.0
HKD1_k127_1021486_10 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000003655 141.0
HKD1_k127_1021486_11 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000001882 129.0
HKD1_k127_1021486_12 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000009884 112.0
HKD1_k127_1021486_2 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 506.0
HKD1_k127_1021486_3 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 490.0
HKD1_k127_1021486_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 474.0
HKD1_k127_1021486_5 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 424.0
HKD1_k127_1021486_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 424.0
HKD1_k127_1021486_7 - K07112 - - 0.0000000000000000000000000000000000000000000000000000003725 202.0
HKD1_k127_1021486_8 - K07112 - - 0.0000000000000000000000000000000000000000000000000001051 192.0
HKD1_k127_1021486_9 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000005485 196.0
HKD1_k127_1100124_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1121.0
HKD1_k127_1100124_1 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 4.611e-217 683.0
HKD1_k127_1100124_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 456.0
HKD1_k127_1100124_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 363.0
HKD1_k127_1100124_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004565 286.0
HKD1_k127_1100124_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000007773 271.0
HKD1_k127_1100124_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000006986 125.0
HKD1_k127_1101479_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.292e-230 739.0
HKD1_k127_1101479_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
HKD1_k127_1101479_2 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
HKD1_k127_1101479_3 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HKD1_k127_1101479_4 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000003155 225.0
HKD1_k127_1101479_5 Domain of unknown function (DUF4342) - - - 0.0000000000003054 78.0
HKD1_k127_1101479_6 BON domain - - - 0.000000002555 67.0
HKD1_k127_1101479_7 Domain of unknown function (DUF4136) - - - 0.00000008228 61.0
HKD1_k127_1101479_8 universal stress protein - - - 0.00009557 54.0
HKD1_k127_1109594_0 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 553.0
HKD1_k127_1109594_1 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 293.0
HKD1_k127_1109594_2 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000000000000000001567 192.0
HKD1_k127_1109594_3 Protein of unknown function (DUF1622) - - - 0.000000000000000000000002898 106.0
HKD1_k127_1136872_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1042.0
HKD1_k127_1136872_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.234e-289 905.0
HKD1_k127_1136872_10 - - - - 0.00000000000000000000000000001284 127.0
HKD1_k127_1136872_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 5.857e-240 749.0
HKD1_k127_1136872_3 TonB dependent receptor - - - 6.573e-237 763.0
HKD1_k127_1136872_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 452.0
HKD1_k127_1136872_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 436.0
HKD1_k127_1136872_6 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 395.0
HKD1_k127_1136872_7 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000004899 224.0
HKD1_k127_1136872_8 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000000001374 201.0
HKD1_k127_1136872_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.000000000000000000000000000000000000000002888 156.0
HKD1_k127_1148279_0 Sortilin, neurotensin receptor 3, - - - 1.911e-315 983.0
HKD1_k127_1148279_1 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 463.0
HKD1_k127_1181504_0 Protein kinase domain K12132 - 2.7.11.1 2.336e-224 728.0
HKD1_k127_1181504_1 Tetratricopeptide repeat K12132 - 2.7.11.1 8.795e-222 727.0
HKD1_k127_1181504_10 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 273.0
HKD1_k127_1181504_11 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.00000000000000000000000000000000000000000000000000000000000008362 235.0
HKD1_k127_1181504_12 HAD-hyrolase-like K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000000000000000000009075 220.0
HKD1_k127_1181504_13 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000435 208.0
HKD1_k127_1181504_14 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.000000000000000000000000000000000000000000000000000004489 207.0
HKD1_k127_1181504_15 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000002485 191.0
HKD1_k127_1181504_16 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000001848 205.0
HKD1_k127_1181504_17 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000002993 169.0
HKD1_k127_1181504_18 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000946 161.0
HKD1_k127_1181504_19 - - - - 0.000000000000000000000000000000000005676 145.0
HKD1_k127_1181504_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 597.0
HKD1_k127_1181504_20 - - - - 0.00000000000000000000000000000001193 142.0
HKD1_k127_1181504_21 RDD family - - - 0.0000000000000000000000000000002668 134.0
HKD1_k127_1181504_22 DinB family - - - 0.00000000000000000000000000001422 123.0
HKD1_k127_1181504_23 - - - - 0.0000000000000000000000004374 119.0
HKD1_k127_1181504_24 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000002053 117.0
HKD1_k127_1181504_25 - - - - 0.0000000000000000001877 95.0
HKD1_k127_1181504_26 RDD family - - - 0.000000000000000007379 89.0
HKD1_k127_1181504_27 RNA polymerase sigma factor K03088 - - 0.000000000000002318 83.0
HKD1_k127_1181504_29 SnoaL-like domain - - - 0.00000000004504 71.0
HKD1_k127_1181504_3 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 554.0
HKD1_k127_1181504_30 - - - - 0.00000000005759 69.0
HKD1_k127_1181504_32 Protein of unknown function (DUF3592) - - - 0.000000007643 68.0
HKD1_k127_1181504_33 Type II secretion system (T2SS), protein K K02460 - - 0.0000001496 64.0
HKD1_k127_1181504_4 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 467.0
HKD1_k127_1181504_5 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 420.0
HKD1_k127_1181504_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 428.0
HKD1_k127_1181504_7 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 375.0
HKD1_k127_1181504_8 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 372.0
HKD1_k127_1181504_9 Pyridine nucleotide-disulphide oxidoreductase K03885 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 350.0
HKD1_k127_1187867_0 efflux transmembrane transporter activity - - - 1.991e-291 918.0
HKD1_k127_1187867_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 632.0
HKD1_k127_1187867_10 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000004289 221.0
HKD1_k127_1187867_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006887 224.0
HKD1_k127_1187867_12 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000005101 233.0
HKD1_k127_1187867_13 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000001659 199.0
HKD1_k127_1187867_14 Single Cache domain 2 K07647 - 2.7.13.3 0.000000000000000000000000000000000000000000000005206 193.0
HKD1_k127_1187867_15 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000002603 163.0
HKD1_k127_1187867_16 - - - - 0.0000000000000000000000000000000000000001342 160.0
HKD1_k127_1187867_17 cyclic nucleotide binding K10914,K21563 - - 0.0000000000000000000000000000000000000004349 158.0
HKD1_k127_1187867_18 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000006874 153.0
HKD1_k127_1187867_19 SnoaL-like domain - - - 0.00000000000000000000000000003375 123.0
HKD1_k127_1187867_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 586.0
HKD1_k127_1187867_20 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.00000000000000000000000002808 125.0
HKD1_k127_1187867_21 glycosyl transferase family 2 - - - 0.00000000000000000000006533 109.0
HKD1_k127_1187867_22 - - - - 0.00000001219 66.0
HKD1_k127_1187867_3 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 593.0
HKD1_k127_1187867_4 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 336.0
HKD1_k127_1187867_5 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 334.0
HKD1_k127_1187867_6 Uncharacterized conserved protein (COG2071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 310.0
HKD1_k127_1187867_7 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 304.0
HKD1_k127_1187867_8 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 292.0
HKD1_k127_1187867_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001689 270.0
HKD1_k127_124710_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1145.0
HKD1_k127_124710_1 alpha-glucuronidase activity K01235 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 0.0 1077.0
HKD1_k127_124710_10 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 492.0
HKD1_k127_124710_11 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 479.0
HKD1_k127_124710_12 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 430.0
HKD1_k127_124710_13 GDSL-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 394.0
HKD1_k127_124710_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 359.0
HKD1_k127_124710_15 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 289.0
HKD1_k127_124710_16 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
HKD1_k127_124710_17 beta-galactosidase activity K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000005495 195.0
HKD1_k127_124710_2 Sodium:solute symporter family - - - 1.28e-247 773.0
HKD1_k127_124710_3 GlcNAc-PI de-N-acetylase - - - 1.155e-237 770.0
HKD1_k127_124710_4 xylulokinase activity K00848,K00854 - 2.7.1.17,2.7.1.5 1.231e-231 727.0
HKD1_k127_124710_5 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 2.972e-225 702.0
HKD1_k127_124710_6 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 617.0
HKD1_k127_124710_7 transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 569.0
HKD1_k127_124710_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 511.0
HKD1_k127_124710_9 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 487.0
HKD1_k127_1260040_0 Cytochrome c K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 289.0
HKD1_k127_1260040_1 UPF0316 protein - - - 0.000000000000000000000000000000000000008798 151.0
HKD1_k127_1260040_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001371 108.0
HKD1_k127_1260040_3 - - - - 0.000000000002695 71.0
HKD1_k127_128229_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 364.0
HKD1_k127_1328792_0 protein histidine kinase activity K03407,K12257 - 2.7.13.3 0.0 2077.0
HKD1_k127_1328792_1 COG NOG06097 non supervised orthologous group - - - 0.0 1322.0
HKD1_k127_1328792_10 Domain of Unknown Function (DUF1259) - - - 0.000000005707 57.0
HKD1_k127_1328792_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1271.0
HKD1_k127_1328792_3 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 471.0
HKD1_k127_1328792_4 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 426.0
HKD1_k127_1328792_5 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 338.0
HKD1_k127_1328792_6 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000003685 196.0
HKD1_k127_1328792_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000004041 105.0
HKD1_k127_1328792_9 transport - - - 0.000000000001297 78.0
HKD1_k127_1339746_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 2.274e-315 985.0
HKD1_k127_1339746_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.025e-297 924.0
HKD1_k127_1339746_10 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 495.0
HKD1_k127_1339746_11 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 479.0
HKD1_k127_1339746_12 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 476.0
HKD1_k127_1339746_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 465.0
HKD1_k127_1339746_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 406.0
HKD1_k127_1339746_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 406.0
HKD1_k127_1339746_16 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HKD1_k127_1339746_17 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 362.0
HKD1_k127_1339746_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 351.0
HKD1_k127_1339746_19 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
HKD1_k127_1339746_2 Surface antigen K07277 - - 7.049e-283 891.0
HKD1_k127_1339746_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 298.0
HKD1_k127_1339746_21 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000006789 207.0
HKD1_k127_1339746_22 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000000000000000000000000232 207.0
HKD1_k127_1339746_23 - - - - 0.000000000000000000000000000000000000000000000000000002624 205.0
HKD1_k127_1339746_24 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000005195 165.0
HKD1_k127_1339746_25 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000001723 149.0
HKD1_k127_1339746_26 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000005575 145.0
HKD1_k127_1339746_27 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000005477 134.0
HKD1_k127_1339746_28 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000003761 138.0
HKD1_k127_1339746_29 - - - - 0.0000000000000000000000000000003445 135.0
HKD1_k127_1339746_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 2.144e-249 773.0
HKD1_k127_1339746_30 Trm112p-like protein K09791 - - 0.00000000000000000000007265 103.0
HKD1_k127_1339746_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.271e-229 730.0
HKD1_k127_1339746_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 581.0
HKD1_k127_1339746_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 563.0
HKD1_k127_1339746_7 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 559.0
HKD1_k127_1339746_8 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 512.0
HKD1_k127_1339746_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 495.0
HKD1_k127_1351861_0 Dehydrogenase K00117 - 1.1.5.2 1.147e-313 973.0
HKD1_k127_1351861_1 TonB-dependent receptor - - - 2.591e-231 752.0
HKD1_k127_1351861_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 345.0
HKD1_k127_1351861_3 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
HKD1_k127_1351861_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 314.0
HKD1_k127_1351861_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 289.0
HKD1_k127_1351861_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000005449 112.0
HKD1_k127_1351861_8 DinB superfamily - - - 0.000000005768 64.0
HKD1_k127_1391513_0 Efflux pump membrane transporter K19585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 396.0
HKD1_k127_1391513_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 242.0
HKD1_k127_1510670_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1560.0
HKD1_k127_1510670_1 COG0433 Predicted ATPase K06915 - - 5e-324 1001.0
HKD1_k127_1510670_10 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 621.0
HKD1_k127_1510670_11 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 581.0
HKD1_k127_1510670_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 552.0
HKD1_k127_1510670_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 535.0
HKD1_k127_1510670_14 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 522.0
HKD1_k127_1510670_15 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 518.0
HKD1_k127_1510670_16 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 495.0
HKD1_k127_1510670_17 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 467.0
HKD1_k127_1510670_18 regulation of response to stimulus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 459.0
HKD1_k127_1510670_19 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 427.0
HKD1_k127_1510670_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.044e-305 947.0
HKD1_k127_1510670_20 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 413.0
HKD1_k127_1510670_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 369.0
HKD1_k127_1510670_22 COGs COG2380 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 342.0
HKD1_k127_1510670_23 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 337.0
HKD1_k127_1510670_24 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 335.0
HKD1_k127_1510670_25 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 308.0
HKD1_k127_1510670_26 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 308.0
HKD1_k127_1510670_28 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 291.0
HKD1_k127_1510670_29 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 289.0
HKD1_k127_1510670_3 copper-translocating P-type ATPase K01533 - 3.6.3.4 1.782e-283 889.0
HKD1_k127_1510670_30 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
HKD1_k127_1510670_31 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
HKD1_k127_1510670_32 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005519 239.0
HKD1_k127_1510670_33 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000001608 220.0
HKD1_k127_1510670_34 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000811 207.0
HKD1_k127_1510670_35 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000002862 178.0
HKD1_k127_1510670_36 phosphorelay signal transduction system K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001217 196.0
HKD1_k127_1510670_37 - - - - 0.000000000000000000000000000000000000001334 154.0
HKD1_k127_1510670_38 - - - - 0.0000000000000000000000000002311 126.0
HKD1_k127_1510670_39 sensor histidine kinase response - - - 0.000000000000000000000002078 115.0
HKD1_k127_1510670_4 AAA domain K03546 - - 4.28e-262 830.0
HKD1_k127_1510670_40 SNARE associated Golgi protein - - - 0.00000000000000000000005918 107.0
HKD1_k127_1510670_41 Domain of unknown function (DUF4142) - - - 0.0000000001325 70.0
HKD1_k127_1510670_43 - - - - 0.000000008321 68.0
HKD1_k127_1510670_44 V4R K07013 - - 0.0000235 53.0
HKD1_k127_1510670_45 - - - - 0.0001978 49.0
HKD1_k127_1510670_5 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 4.298e-262 825.0
HKD1_k127_1510670_6 AMP-binding enzyme K01897 - 6.2.1.3 6.198e-256 803.0
HKD1_k127_1510670_7 Belongs to the glycosyl hydrolase 43 family - - - 1.584e-238 749.0
HKD1_k127_1510670_8 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 1.87e-203 642.0
HKD1_k127_1510670_9 MacB-like periplasmic core domain - - - 4.622e-196 633.0
HKD1_k127_1579219_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1181.0
HKD1_k127_1579219_1 Domain of unknown function (DUF5118) - - - 0.0 1107.0
HKD1_k127_1579219_10 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 469.0
HKD1_k127_1579219_11 AMIN domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 480.0
HKD1_k127_1579219_12 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
HKD1_k127_1579219_13 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 424.0
HKD1_k127_1579219_14 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 335.0
HKD1_k127_1579219_15 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 331.0
HKD1_k127_1579219_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 312.0
HKD1_k127_1579219_17 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 291.0
HKD1_k127_1579219_18 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000387 274.0
HKD1_k127_1579219_19 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008007 274.0
HKD1_k127_1579219_2 Bacterial regulatory protein, Fis family - - - 9.212e-224 706.0
HKD1_k127_1579219_20 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 277.0
HKD1_k127_1579219_21 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006545 243.0
HKD1_k127_1579219_22 - - - - 0.0000000000000000000000000000000000000000000000000000000002429 216.0
HKD1_k127_1579219_23 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000008118 193.0
HKD1_k127_1579219_24 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000002318 171.0
HKD1_k127_1579219_25 - - - - 0.00000000000000000000000000000000000003664 162.0
HKD1_k127_1579219_26 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.0000000000000000000000000000000000001244 143.0
HKD1_k127_1579219_27 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000006561 162.0
HKD1_k127_1579219_28 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000002821 144.0
HKD1_k127_1579219_29 - - - - 0.000000000000000000000000000001149 136.0
HKD1_k127_1579219_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.242e-223 712.0
HKD1_k127_1579219_30 - - - - 0.0000000000000000000000000003905 128.0
HKD1_k127_1579219_33 Protein of unknown function (DUF494) K03747 - - 0.00000000000000001095 87.0
HKD1_k127_1579219_34 Redoxin K03564 - 1.11.1.15 0.0000000003624 63.0
HKD1_k127_1579219_35 Putative restriction endonuclease - - - 0.000000007223 59.0
HKD1_k127_1579219_36 - - - - 0.00000008546 65.0
HKD1_k127_1579219_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.239e-220 693.0
HKD1_k127_1579219_5 lysine biosynthetic process via aminoadipic acid - - - 1.54e-217 706.0
HKD1_k127_1579219_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 603.0
HKD1_k127_1579219_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 559.0
HKD1_k127_1579219_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 479.0
HKD1_k127_1579219_9 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 488.0
HKD1_k127_1682412_0 4Fe-4S dicluster domain K00184 - - 0.0 1267.0
HKD1_k127_1682412_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1010.0
HKD1_k127_1682412_10 Pfam:SusD K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 456.0
HKD1_k127_1682412_11 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 434.0
HKD1_k127_1682412_12 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 410.0
HKD1_k127_1682412_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 402.0
HKD1_k127_1682412_14 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 393.0
HKD1_k127_1682412_15 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 389.0
HKD1_k127_1682412_16 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 391.0
HKD1_k127_1682412_17 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 359.0
HKD1_k127_1682412_18 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 357.0
HKD1_k127_1682412_19 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 321.0
HKD1_k127_1682412_2 Prolyl oligopeptidase family - - - 1.283e-317 1001.0
HKD1_k127_1682412_20 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 316.0
HKD1_k127_1682412_21 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 317.0
HKD1_k127_1682412_22 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
HKD1_k127_1682412_23 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
HKD1_k127_1682412_24 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000176 279.0
HKD1_k127_1682412_25 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000957 245.0
HKD1_k127_1682412_26 transport - - - 0.00000000000000000000000000000000000000000000000000000001896 207.0
HKD1_k127_1682412_27 - - - - 0.0000000000000000000000000000000000000184 161.0
HKD1_k127_1682412_29 Protein of unknown function (DUF3341) - - - 0.0000000000000009478 77.0
HKD1_k127_1682412_3 Alpha mannosidase, middle domain K01191 - 3.2.1.24 1.069e-274 871.0
HKD1_k127_1682412_30 - - - - 0.00000000002067 66.0
HKD1_k127_1682412_4 Heparinase II/III-like protein - - - 6.408e-267 873.0
HKD1_k127_1682412_5 Polysulphide reductase, NrfD K00185 - - 5.562e-248 772.0
HKD1_k127_1682412_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.649e-206 677.0
HKD1_k127_1682412_7 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 539.0
HKD1_k127_1682412_8 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 500.0
HKD1_k127_1682412_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 494.0
HKD1_k127_168902_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 536.0
HKD1_k127_168902_1 Acetyltransferase - - - 0.00000000000000000000000000005106 125.0
HKD1_k127_169535_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 1.397e-318 1005.0
HKD1_k127_169535_1 GMC oxidoreductase - - - 2.315e-220 698.0
HKD1_k127_169535_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008129 224.0
HKD1_k127_169535_11 Globin - - - 0.0000000000000000000000000000000000000000000005454 171.0
HKD1_k127_169535_12 SnoaL-like domain - - - 0.0000000000000000000000000000007466 128.0
HKD1_k127_169535_13 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000001256 92.0
HKD1_k127_169535_14 - - - - 0.00000000127 63.0
HKD1_k127_169535_15 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.000003938 55.0
HKD1_k127_169535_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 505.0
HKD1_k127_169535_3 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 417.0
HKD1_k127_169535_4 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 373.0
HKD1_k127_169535_5 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 357.0
HKD1_k127_169535_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 308.0
HKD1_k127_169535_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
HKD1_k127_169535_8 - K21429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001688 265.0
HKD1_k127_169535_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003553 253.0
HKD1_k127_1754832_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 530.0
HKD1_k127_1754832_1 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000001294 179.0
HKD1_k127_1754832_2 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000003165 130.0
HKD1_k127_1754832_4 Protein of unknown function (DUF1697) - - - 0.00000193 57.0
HKD1_k127_184023_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.343e-212 664.0
HKD1_k127_184023_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
HKD1_k127_184023_10 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000005288 149.0
HKD1_k127_184023_11 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000004989 141.0
HKD1_k127_184023_12 Outer membrane lipoprotein - - - 0.00000000000000000000000201 112.0
HKD1_k127_184023_13 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000003884 100.0
HKD1_k127_184023_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000007561 96.0
HKD1_k127_184023_15 Cytochrome C assembly protein - - - 0.000000000000000001057 96.0
HKD1_k127_184023_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 391.0
HKD1_k127_184023_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 335.0
HKD1_k127_184023_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
HKD1_k127_184023_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000004452 247.0
HKD1_k127_184023_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000001032 191.0
HKD1_k127_184023_7 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000008317 171.0
HKD1_k127_184023_8 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000005387 162.0
HKD1_k127_184023_9 OmpA family K03640 - - 0.000000000000000000000000000000000000002318 157.0
HKD1_k127_1886323_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004711 263.0
HKD1_k127_1886323_1 WHG domain - - - 0.000000000000000000000000000000000000000001138 162.0
HKD1_k127_1886323_2 MMPL family - - - 0.0000000000000000002697 92.0
HKD1_k127_1930270_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.491e-298 930.0
HKD1_k127_1930270_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 6.725e-294 940.0
HKD1_k127_1930270_10 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 418.0
HKD1_k127_1930270_11 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 397.0
HKD1_k127_1930270_12 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 386.0
HKD1_k127_1930270_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 340.0
HKD1_k127_1930270_14 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006572 279.0
HKD1_k127_1930270_15 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002511 254.0
HKD1_k127_1930270_16 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000002117 233.0
HKD1_k127_1930270_17 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000001319 222.0
HKD1_k127_1930270_18 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000002996 226.0
HKD1_k127_1930270_19 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000004266 204.0
HKD1_k127_1930270_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.405e-270 837.0
HKD1_k127_1930270_20 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000001392 204.0
HKD1_k127_1930270_21 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000005061 190.0
HKD1_k127_1930270_22 Thioredoxin - - - 0.000000000000000000000000000000000000000006658 163.0
HKD1_k127_1930270_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000009823 121.0
HKD1_k127_1930270_24 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000001118 103.0
HKD1_k127_1930270_26 MotA/TolQ/ExbB proton channel family - - - 0.00000002559 66.0
HKD1_k127_1930270_28 - - - - 0.00001271 48.0
HKD1_k127_1930270_29 23S rRNA-intervening sequence protein - - - 0.00005615 53.0
HKD1_k127_1930270_3 tRNA synthetases class I (M) K01874 - 6.1.1.10 9.127e-249 779.0
HKD1_k127_1930270_31 - - - - 0.0001665 45.0
HKD1_k127_1930270_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 555.0
HKD1_k127_1930270_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 553.0
HKD1_k127_1930270_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 514.0
HKD1_k127_1930270_7 EAL domain K13950,K21025 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 487.0
HKD1_k127_1930270_8 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 458.0
HKD1_k127_1930270_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
HKD1_k127_1932673_0 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 567.0
HKD1_k127_1932673_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
HKD1_k127_1932673_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001664 163.0
HKD1_k127_1932673_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000009916 96.0
HKD1_k127_1932673_4 DNA polymerase X family K02347 - - 0.00000000000001951 81.0
HKD1_k127_2015119_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 578.0
HKD1_k127_2015119_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 495.0
HKD1_k127_2015119_10 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000002237 164.0
HKD1_k127_2015119_11 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000007199 157.0
HKD1_k127_2015119_12 Surface antigen - - - 0.0000000000000000000000000000000000004983 155.0
HKD1_k127_2015119_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 400.0
HKD1_k127_2015119_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 394.0
HKD1_k127_2015119_4 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000791 271.0
HKD1_k127_2015119_5 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007044 266.0
HKD1_k127_2015119_6 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000001701 186.0
HKD1_k127_2015119_7 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000007124 172.0
HKD1_k127_2015119_8 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000003385 162.0
HKD1_k127_2015119_9 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000003411 158.0
HKD1_k127_2018447_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1146.0
HKD1_k127_2018447_1 Hsp70 protein K03569 - - 5.879e-205 640.0
HKD1_k127_2018447_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005448 251.0
HKD1_k127_2018447_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001348 260.0
HKD1_k127_2018447_12 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001618 258.0
HKD1_k127_2018447_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000009682 234.0
HKD1_k127_2018447_14 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000000003062 213.0
HKD1_k127_2018447_15 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000002892 175.0
HKD1_k127_2018447_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000001048 144.0
HKD1_k127_2018447_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 1.582e-195 615.0
HKD1_k127_2018447_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 556.0
HKD1_k127_2018447_4 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 544.0
HKD1_k127_2018447_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 531.0
HKD1_k127_2018447_6 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 426.0
HKD1_k127_2018447_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 368.0
HKD1_k127_2018447_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 313.0
HKD1_k127_2018447_9 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000509 308.0
HKD1_k127_2024537_0 Peptidase family M1 domain - - - 0.0 1036.0
HKD1_k127_2024537_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.785e-293 916.0
HKD1_k127_2024537_10 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
HKD1_k127_2024537_11 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 297.0
HKD1_k127_2024537_12 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
HKD1_k127_2024537_13 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001453 276.0
HKD1_k127_2024537_14 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009259 273.0
HKD1_k127_2024537_15 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
HKD1_k127_2024537_16 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
HKD1_k127_2024537_17 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000005848 185.0
HKD1_k127_2024537_18 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000816 181.0
HKD1_k127_2024537_19 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000003704 175.0
HKD1_k127_2024537_2 GMC oxidoreductase K03333 - 1.1.3.6 1.552e-208 672.0
HKD1_k127_2024537_20 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000002526 179.0
HKD1_k127_2024537_21 DoxX K15977 - - 0.000000000000000000000000000000000000000003043 162.0
HKD1_k127_2024537_22 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000003334 149.0
HKD1_k127_2024537_24 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000001769 95.0
HKD1_k127_2024537_25 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000002867 67.0
HKD1_k127_2024537_26 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.0000002183 63.0
HKD1_k127_2024537_3 response to antibiotic K00573 - 2.1.1.77 1.363e-205 657.0
HKD1_k127_2024537_4 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 598.0
HKD1_k127_2024537_5 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 501.0
HKD1_k127_2024537_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 462.0
HKD1_k127_2024537_7 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 392.0
HKD1_k127_2024537_8 calcium:proton antiporter activity K07300 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 359.0
HKD1_k127_2024537_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
HKD1_k127_2034519_0 cellulose binding - - - 3.297e-216 694.0
HKD1_k127_2034519_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000002262 81.0
HKD1_k127_2044458_0 WD40-like Beta Propeller Repeat - - - 7.767e-321 1013.0
HKD1_k127_2044458_1 Acetyl xylan esterase (AXE1) - - - 7.236e-282 885.0
HKD1_k127_2044458_10 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000159 98.0
HKD1_k127_2044458_2 CarboxypepD_reg-like domain - - - 1.159e-274 881.0
HKD1_k127_2044458_3 Bacterial regulatory protein, Fis family - - - 4.357e-215 690.0
HKD1_k127_2044458_4 PAS domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 491.0
HKD1_k127_2044458_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001953 285.0
HKD1_k127_2044458_6 lytic transglycosylase activity K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000006401 177.0
HKD1_k127_2044458_7 RF-1 domain K15034 - - 0.0000000000000000000000000000000000000003238 155.0
HKD1_k127_2044458_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000008838 148.0
HKD1_k127_2044458_9 - - - - 0.0000000000000000000002517 107.0
HKD1_k127_2048409_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 3.16e-210 662.0
HKD1_k127_2048409_1 Major Facilitator Superfamily - - - 4.154e-204 645.0
HKD1_k127_2048409_10 - - - - 0.0000002039 63.0
HKD1_k127_2048409_11 PFAM alpha beta hydrolase fold - - - 0.00000898 54.0
HKD1_k127_2048409_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 496.0
HKD1_k127_2048409_4 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 410.0
HKD1_k127_2048409_5 Transcriptional regulator - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 424.0
HKD1_k127_2048409_6 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009483 298.0
HKD1_k127_2048409_7 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005931 278.0
HKD1_k127_2048409_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 265.0
HKD1_k127_2048409_9 PUCC protein - - - 0.0000000000000000000000000000000000000000000001772 185.0
HKD1_k127_2051566_0 Protein of unknown function (DUF1595) - - - 0.0 1037.0
HKD1_k127_2051566_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000001554 123.0
HKD1_k127_2051566_2 Protein of unknown function (DUF1552) - - - 0.0000000533 54.0
HKD1_k127_2074023_0 Peptidase family M28 - - - 5.943e-252 788.0
HKD1_k127_2074023_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 514.0
HKD1_k127_2074023_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 308.0
HKD1_k127_2074023_11 - - - - 0.000000009759 62.0
HKD1_k127_2074023_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 475.0
HKD1_k127_2074023_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 423.0
HKD1_k127_2074023_4 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 414.0
HKD1_k127_2074023_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 384.0
HKD1_k127_2074023_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 362.0
HKD1_k127_2074023_7 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 360.0
HKD1_k127_2074023_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 352.0
HKD1_k127_2074023_9 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 351.0
HKD1_k127_207950_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1074.0
HKD1_k127_207950_1 Participates in both transcription termination and antitermination K02600 - - 1.401e-221 693.0
HKD1_k127_207950_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000000002309 239.0
HKD1_k127_207950_11 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000001367 224.0
HKD1_k127_207950_12 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000009836 224.0
HKD1_k127_207950_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000001024 224.0
HKD1_k127_207950_14 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000002286 177.0
HKD1_k127_207950_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000009437 171.0
HKD1_k127_207950_16 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000003584 163.0
HKD1_k127_207950_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000001158 160.0
HKD1_k127_207950_18 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000006282 140.0
HKD1_k127_207950_19 - - - - 0.00000000000000000000000000007992 119.0
HKD1_k127_207950_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 382.0
HKD1_k127_207950_20 - - - - 0.000000000000000000000000003579 118.0
HKD1_k127_207950_21 - - - - 0.000000000000000000000000006666 112.0
HKD1_k127_207950_22 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000000000000000000001149 112.0
HKD1_k127_207950_23 - - - - 0.00000000000006455 73.0
HKD1_k127_207950_25 Lipopolysaccharide-assembly - - - 0.0000000004807 68.0
HKD1_k127_207950_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
HKD1_k127_207950_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 364.0
HKD1_k127_207950_5 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 346.0
HKD1_k127_207950_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
HKD1_k127_207950_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
HKD1_k127_207950_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
HKD1_k127_207950_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000002898 258.0
HKD1_k127_2089215_0 Amidohydrolase family - - - 1.605e-236 747.0
HKD1_k127_2089215_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 631.0
HKD1_k127_2089215_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 599.0
HKD1_k127_2089215_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 491.0
HKD1_k127_2089215_4 - - - - 0.0000000000000000000000000000000000000000000000008649 187.0
HKD1_k127_2089215_5 Outer membrane protein beta-barrel domain - - - 0.0000003744 58.0
HKD1_k127_2090034_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 610.0
HKD1_k127_2090034_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 488.0
HKD1_k127_2090034_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 343.0
HKD1_k127_2090034_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005281 267.0
HKD1_k127_2090034_4 Membrane protein involved in cytochrome C biogenesis - - - 0.00000000000000000000000000000000000000000000008811 174.0
HKD1_k127_2090034_5 Transcriptional regulator K07979 - - 0.0000000000000000000000000000000000000000000002372 171.0
HKD1_k127_2090034_6 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000002854 135.0
HKD1_k127_2090034_7 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000001825 88.0
HKD1_k127_2090034_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00002008 57.0
HKD1_k127_2091458_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 3.2e-207 672.0
HKD1_k127_2091458_1 periplasmic protein thiol disulfide K02199 - - 0.00000000000000000000000000002123 121.0
HKD1_k127_2091458_2 subunit of a heme lyase K02200 - - 0.0000000000000000000000002933 116.0
HKD1_k127_2091458_3 PFAM OsmC family protein - - - 0.000000000000000000001718 101.0
HKD1_k127_2091458_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000005756 94.0
HKD1_k127_2111700_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 527.0
HKD1_k127_2111700_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 436.0
HKD1_k127_2111700_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 422.0
HKD1_k127_2111700_3 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 411.0
HKD1_k127_2111700_4 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 383.0
HKD1_k127_2111700_5 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001634 207.0
HKD1_k127_2111700_6 - - - - 0.0000000000000001358 87.0
HKD1_k127_2117554_0 cellulose binding - - - 0.0 1480.0
HKD1_k127_2117554_1 aminopeptidase activity K07004 - - 2.6e-322 1000.0
HKD1_k127_2117554_10 Flavin-binding monooxygenase-like K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 467.0
HKD1_k127_2117554_11 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 467.0
HKD1_k127_2117554_12 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 454.0
HKD1_k127_2117554_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 444.0
HKD1_k127_2117554_14 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 402.0
HKD1_k127_2117554_15 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
HKD1_k127_2117554_16 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
HKD1_k127_2117554_17 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 345.0
HKD1_k127_2117554_18 competence protein COMEC K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 357.0
HKD1_k127_2117554_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 316.0
HKD1_k127_2117554_2 MacB-like periplasmic core domain - - - 1.813e-321 1003.0
HKD1_k127_2117554_20 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
HKD1_k127_2117554_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000001026 231.0
HKD1_k127_2117554_22 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
HKD1_k127_2117554_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000002545 205.0
HKD1_k127_2117554_24 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000001235 188.0
HKD1_k127_2117554_25 - - - - 0.00000000000000000000000000000000000000000000000000664 196.0
HKD1_k127_2117554_27 Cysteine-rich CPXCG - - - 0.00000000000000000000000002798 117.0
HKD1_k127_2117554_28 - - - - 0.000000000000000008313 88.0
HKD1_k127_2117554_3 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 2.159e-241 763.0
HKD1_k127_2117554_31 energy transducer activity K03832 - - 0.000005201 55.0
HKD1_k127_2117554_32 Protein with unknown function (DUF469) - - - 0.0000355 51.0
HKD1_k127_2117554_4 Peptidase family M28 - - - 2.158e-218 691.0
HKD1_k127_2117554_5 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 586.0
HKD1_k127_2117554_6 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 554.0
HKD1_k127_2117554_7 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 524.0
HKD1_k127_2117554_8 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 522.0
HKD1_k127_2117554_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 521.0
HKD1_k127_2124411_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.218e-239 754.0
HKD1_k127_2124411_1 Major Facilitator Superfamily - - - 1.383e-194 622.0
HKD1_k127_2124411_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 320.0
HKD1_k127_2124411_3 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 303.0
HKD1_k127_2124411_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 294.0
HKD1_k127_2124411_5 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000008697 136.0
HKD1_k127_2124411_6 - - - - 0.0000000000000000001714 94.0
HKD1_k127_2124411_7 DoxX-like family - - - 0.000000000000000004513 93.0
HKD1_k127_2124411_8 - - - - 0.00000000002898 73.0
HKD1_k127_2124411_9 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.0002488 47.0
HKD1_k127_215724_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 501.0
HKD1_k127_215724_1 lipolytic protein G-D-S-L family K01126,K01181,K01186 - 3.1.4.46,3.2.1.18,3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 298.0
HKD1_k127_215724_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000001357 52.0
HKD1_k127_2162066_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 7.082e-243 762.0
HKD1_k127_2162066_1 small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 445.0
HKD1_k127_2162066_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000001383 173.0
HKD1_k127_2162066_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000003026 166.0
HKD1_k127_2162066_4 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000004129 137.0
HKD1_k127_2162066_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000001666 114.0
HKD1_k127_2180544_0 ABC transporter transmembrane region K11085 - - 4.081e-218 692.0
HKD1_k127_2180544_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 417.0
HKD1_k127_2180544_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 411.0
HKD1_k127_2180544_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 368.0
HKD1_k127_2180544_4 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000002418 211.0
HKD1_k127_2180544_5 PglZ domain - - - 0.000000000000000000000000000295 113.0
HKD1_k127_2180544_6 Outer membrane protein beta-barrel domain - - - 0.000000000000009649 84.0
HKD1_k127_2180544_7 Outer membrane protein beta-barrel domain - - - 0.0000000000001052 81.0
HKD1_k127_2208272_0 nucleotidyltransferase activity K01154,K07076 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 380.0
HKD1_k127_2208272_1 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000006252 221.0
HKD1_k127_2208272_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000001162 72.0
HKD1_k127_2208272_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000008483 74.0
HKD1_k127_2259840_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1346.0
HKD1_k127_2259840_1 Sortilin, neurotensin receptor 3, - - - 0.0 1317.0
HKD1_k127_2259840_10 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.295e-242 770.0
HKD1_k127_2259840_11 l-lactate permease K02550,K03303 - - 3.042e-221 700.0
HKD1_k127_2259840_12 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 5.805e-220 690.0
HKD1_k127_2259840_13 Domain of unknown function (DUF3416) K16147 - 2.4.99.16 9.049e-210 674.0
HKD1_k127_2259840_14 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 1.924e-208 683.0
HKD1_k127_2259840_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.953e-200 628.0
HKD1_k127_2259840_16 Insulinase (Peptidase family M16) - - - 1.284e-198 626.0
HKD1_k127_2259840_17 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 635.0
HKD1_k127_2259840_18 Glycine D-amino acid oxidase (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 579.0
HKD1_k127_2259840_19 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 549.0
HKD1_k127_2259840_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1137.0
HKD1_k127_2259840_20 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 542.0
HKD1_k127_2259840_21 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 535.0
HKD1_k127_2259840_22 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 509.0
HKD1_k127_2259840_23 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 509.0
HKD1_k127_2259840_24 4-alpha-glucanotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 492.0
HKD1_k127_2259840_25 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 456.0
HKD1_k127_2259840_26 Zn-dependent protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
HKD1_k127_2259840_27 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 441.0
HKD1_k127_2259840_28 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 413.0
HKD1_k127_2259840_29 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 417.0
HKD1_k127_2259840_3 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1105.0
HKD1_k127_2259840_30 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 402.0
HKD1_k127_2259840_31 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 395.0
HKD1_k127_2259840_32 Bacterial dnaA protein helix-turn-helix domain K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 407.0
HKD1_k127_2259840_33 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
HKD1_k127_2259840_34 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 392.0
HKD1_k127_2259840_35 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
HKD1_k127_2259840_36 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 365.0
HKD1_k127_2259840_37 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 372.0
HKD1_k127_2259840_38 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 370.0
HKD1_k127_2259840_39 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 354.0
HKD1_k127_2259840_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1102.0
HKD1_k127_2259840_40 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 363.0
HKD1_k127_2259840_41 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 354.0
HKD1_k127_2259840_42 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 348.0
HKD1_k127_2259840_43 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 332.0
HKD1_k127_2259840_44 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 329.0
HKD1_k127_2259840_45 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
HKD1_k127_2259840_46 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 306.0
HKD1_k127_2259840_47 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 295.0
HKD1_k127_2259840_48 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 296.0
HKD1_k127_2259840_49 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008277 287.0
HKD1_k127_2259840_5 CarboxypepD_reg-like domain - - - 2e-323 1033.0
HKD1_k127_2259840_50 trehalose biosynthetic process K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000272 292.0
HKD1_k127_2259840_51 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
HKD1_k127_2259840_52 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HKD1_k127_2259840_53 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
HKD1_k127_2259840_54 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006341 271.0
HKD1_k127_2259840_55 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001284 273.0
HKD1_k127_2259840_56 dTDP-4-dehydrorhamnose reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002106 261.0
HKD1_k127_2259840_57 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008318 265.0
HKD1_k127_2259840_58 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004078 264.0
HKD1_k127_2259840_59 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
HKD1_k127_2259840_6 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 3.396e-309 959.0
HKD1_k127_2259840_60 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000001966 254.0
HKD1_k127_2259840_61 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002326 252.0
HKD1_k127_2259840_62 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000003942 236.0
HKD1_k127_2259840_64 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000282 216.0
HKD1_k127_2259840_65 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000002795 235.0
HKD1_k127_2259840_66 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000002532 222.0
HKD1_k127_2259840_67 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000001138 216.0
HKD1_k127_2259840_68 MerR family regulatory protein K19591 - - 0.0000000000000000000000000000000000000000000000000000000008825 222.0
HKD1_k127_2259840_69 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000001743 205.0
HKD1_k127_2259840_7 hydrolase activity, hydrolyzing O-glycosyl compounds K05343 - 3.2.1.1,5.4.99.16 8.942e-297 917.0
HKD1_k127_2259840_70 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000001845 209.0
HKD1_k127_2259840_71 peptidase S8 - - - 0.00000000000000000000000000000000000000000000000000003543 204.0
HKD1_k127_2259840_72 - - - - 0.00000000000000000000000000000000000000000000002771 175.0
HKD1_k127_2259840_73 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000003051 178.0
HKD1_k127_2259840_74 Putative lumazine-binding - - - 0.0000000000000000000000000000000000000000001959 166.0
HKD1_k127_2259840_75 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000005108 170.0
HKD1_k127_2259840_76 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000698 153.0
HKD1_k127_2259840_77 - - - - 0.000000000000000000000000000000000000004508 147.0
HKD1_k127_2259840_78 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000002091 155.0
HKD1_k127_2259840_79 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000002179 143.0
HKD1_k127_2259840_8 Domain of unknown function (DUF5117) - - - 3.505e-257 831.0
HKD1_k127_2259840_80 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000001295 156.0
HKD1_k127_2259840_81 polysaccharide export K01991 - - 0.0000000000000000000000000000000005794 139.0
HKD1_k127_2259840_82 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000001738 130.0
HKD1_k127_2259840_83 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000002061 132.0
HKD1_k127_2259840_84 Cold shock K03704 - - 0.000000000000000000000000000000007807 129.0
HKD1_k127_2259840_85 - - - - 0.000000000000000000000000000009507 126.0
HKD1_k127_2259840_86 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000005258 118.0
HKD1_k127_2259840_87 of the alpha beta superfamily K06889 - - 0.00000000000000000000000001038 121.0
HKD1_k127_2259840_88 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000002069 113.0
HKD1_k127_2259840_89 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000004813 106.0
HKD1_k127_2259840_9 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.044e-246 771.0
HKD1_k127_2259840_90 - - - - 0.0000000000000000000001621 108.0
HKD1_k127_2259840_91 - - - - 0.000000000000000000001705 103.0
HKD1_k127_2259840_92 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000007844 62.0
HKD1_k127_2259840_93 - - - - 0.0000000009743 61.0
HKD1_k127_2259840_95 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0009135 49.0
HKD1_k127_2265174_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 8.637e-274 889.0
HKD1_k127_2265174_1 Protein kinase domain K12132 - 2.7.11.1 2.096e-233 737.0
HKD1_k127_2265174_10 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 484.0
HKD1_k127_2265174_11 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 490.0
HKD1_k127_2265174_12 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HKD1_k127_2265174_13 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 413.0
HKD1_k127_2265174_14 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 370.0
HKD1_k127_2265174_15 tryptophan 2,3-dioxygenase activity K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 356.0
HKD1_k127_2265174_16 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 326.0
HKD1_k127_2265174_17 creatininase K01470,K22232 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002684 285.0
HKD1_k127_2265174_18 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005955 254.0
HKD1_k127_2265174_19 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000003389 221.0
HKD1_k127_2265174_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 6.154e-196 616.0
HKD1_k127_2265174_20 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000001184 205.0
HKD1_k127_2265174_21 - - - - 0.0000000000000000000000000002191 123.0
HKD1_k127_2265174_22 - - - - 0.0000002511 56.0
HKD1_k127_2265174_3 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 565.0
HKD1_k127_2265174_4 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 562.0
HKD1_k127_2265174_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 563.0
HKD1_k127_2265174_6 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 532.0
HKD1_k127_2265174_7 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 527.0
HKD1_k127_2265174_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 520.0
HKD1_k127_2265174_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 512.0
HKD1_k127_2276698_0 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 613.0
HKD1_k127_2276698_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 501.0
HKD1_k127_2276698_2 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 346.0
HKD1_k127_2276698_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001083 264.0
HKD1_k127_2276698_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000009187 226.0
HKD1_k127_2276698_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000006603 124.0
HKD1_k127_2276698_6 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000002939 115.0
HKD1_k127_2327218_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.312e-264 835.0
HKD1_k127_2327218_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 3.903e-258 801.0
HKD1_k127_2327218_2 Amidohydrolase family K06015 - 3.5.1.81 2.073e-215 682.0
HKD1_k127_2327218_3 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000002749 169.0
HKD1_k127_2327218_5 CarboxypepD_reg-like domain - - - 0.000000000000000000000001704 113.0
HKD1_k127_2327218_6 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000003856 103.0
HKD1_k127_2327218_7 OsmC-like protein - - - 0.0000001868 61.0
HKD1_k127_2333781_0 ABC transporter transmembrane region K11085 - - 3.025e-295 923.0
HKD1_k127_2333781_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 3.272e-253 800.0
HKD1_k127_2333781_10 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
HKD1_k127_2333781_12 - - - - 0.00006773 51.0
HKD1_k127_2333781_2 Major facilitator Superfamily K08369 - - 1.524e-217 691.0
HKD1_k127_2333781_3 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 623.0
HKD1_k127_2333781_4 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 610.0
HKD1_k127_2333781_5 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 512.0
HKD1_k127_2333781_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 467.0
HKD1_k127_2333781_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 372.0
HKD1_k127_2333781_8 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 351.0
HKD1_k127_2333781_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 331.0
HKD1_k127_2341088_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1212.0
HKD1_k127_2341088_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 4.7e-310 969.0
HKD1_k127_2341088_10 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000001079 235.0
HKD1_k127_2341088_11 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD1_k127_2341088_12 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000004924 204.0
HKD1_k127_2341088_13 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000008759 201.0
HKD1_k127_2341088_14 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000001061 194.0
HKD1_k127_2341088_15 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000001386 208.0
HKD1_k127_2341088_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000002767 194.0
HKD1_k127_2341088_17 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000003981 172.0
HKD1_k127_2341088_18 FixH - - - 0.000000000000000000000000000001 136.0
HKD1_k127_2341088_19 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000005334 121.0
HKD1_k127_2341088_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 578.0
HKD1_k127_2341088_20 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000001681 115.0
HKD1_k127_2341088_21 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.000000000000000000000000239 111.0
HKD1_k127_2341088_22 membrane transporter protein K07090 - - 0.00000000000000000000000105 114.0
HKD1_k127_2341088_23 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000003995 120.0
HKD1_k127_2341088_24 - - - - 0.000000000001014 79.0
HKD1_k127_2341088_25 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000000004586 69.0
HKD1_k127_2341088_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 470.0
HKD1_k127_2341088_4 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 469.0
HKD1_k127_2341088_5 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 335.0
HKD1_k127_2341088_6 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 317.0
HKD1_k127_2341088_7 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 326.0
HKD1_k127_2341088_8 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 309.0
HKD1_k127_2341088_9 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000246 307.0
HKD1_k127_2343693_0 tail collar domain protein - - - 0.000000000000000000000000000000003693 148.0
HKD1_k127_2343693_1 MlaD protein K06192 - - 0.00000000000000000000000000000002411 135.0
HKD1_k127_2343693_2 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000006876 94.0
HKD1_k127_2350733_0 Prolyl oligopeptidase family - - - 2.784e-288 913.0
HKD1_k127_2350733_1 Aldehyde dehydrogenase family K22187 - - 7.305e-271 852.0
HKD1_k127_2350733_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 338.0
HKD1_k127_2350733_11 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 333.0
HKD1_k127_2350733_12 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 330.0
HKD1_k127_2350733_13 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
HKD1_k127_2350733_14 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 304.0
HKD1_k127_2350733_15 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 292.0
HKD1_k127_2350733_16 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004726 258.0
HKD1_k127_2350733_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000001991 199.0
HKD1_k127_2350733_18 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD1_k127_2350733_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001197 198.0
HKD1_k127_2350733_2 Bacterial regulatory protein, Fis family - - - 4.702e-220 694.0
HKD1_k127_2350733_20 - - - - 0.0000000000000000000000000000000000000000002789 165.0
HKD1_k127_2350733_21 Intracellular proteinase inhibitor - - - 0.0000000000000000000000000000000001061 140.0
HKD1_k127_2350733_22 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000002963 123.0
HKD1_k127_2350733_23 - - - - 0.00000000000000000000000000009115 134.0
HKD1_k127_2350733_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000955 96.0
HKD1_k127_2350733_25 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000009825 78.0
HKD1_k127_2350733_26 - - - - 0.000000001192 67.0
HKD1_k127_2350733_27 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00004366 57.0
HKD1_k127_2350733_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 498.0
HKD1_k127_2350733_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 490.0
HKD1_k127_2350733_5 HAMP domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 450.0
HKD1_k127_2350733_6 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 417.0
HKD1_k127_2350733_7 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
HKD1_k127_2350733_8 Bacterial extracellular solute-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 371.0
HKD1_k127_2350733_9 Bacterial extracellular solute-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 370.0
HKD1_k127_2405983_0 Dienelactone hydrolase family - - - 4.33e-254 802.0
HKD1_k127_2405983_1 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004842 280.0
HKD1_k127_2405983_2 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000007512 190.0
HKD1_k127_2405983_3 - - - - 0.0000000000000000000000000000000000000006879 166.0
HKD1_k127_2405983_4 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000009169 147.0
HKD1_k127_2405983_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000002478 152.0
HKD1_k127_2405983_6 ASCH - - - 0.0000000000000000000000000002584 119.0
HKD1_k127_2405983_7 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000157 95.0
HKD1_k127_2451535_0 Protein kinase domain K12132 - 2.7.11.1 2.772e-313 972.0
HKD1_k127_2451535_1 Hydrolase Family 16 - - - 2.132e-231 729.0
HKD1_k127_2451535_2 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 490.0
HKD1_k127_2451535_3 WYL domain - - - 0.0000000000000000000000000000000000000000000004021 175.0
HKD1_k127_2451535_5 - - - - 0.00000000007948 67.0
HKD1_k127_2451535_6 heat shock protein binding - - - 0.0000000211 61.0
HKD1_k127_2503869_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 5.23e-207 656.0
HKD1_k127_2503869_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000002779 99.0
HKD1_k127_2503869_3 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000001083 74.0
HKD1_k127_2503869_4 23S rRNA-intervening sequence protein - - - 0.000003141 53.0
HKD1_k127_2560911_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.12e-211 665.0
HKD1_k127_2560911_1 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 550.0
HKD1_k127_2560911_11 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000002972 57.0
HKD1_k127_2560911_2 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 538.0
HKD1_k127_2560911_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 482.0
HKD1_k127_2560911_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 383.0
HKD1_k127_2560911_5 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 329.0
HKD1_k127_2560911_6 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 316.0
HKD1_k127_2560911_7 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000012 275.0
HKD1_k127_2560911_8 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006087 242.0
HKD1_k127_2560911_9 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000008043 169.0
HKD1_k127_2723450_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 436.0
HKD1_k127_2723450_1 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 376.0
HKD1_k127_2723450_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 312.0
HKD1_k127_2723450_3 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000000000000000000000000000001078 190.0
HKD1_k127_2723450_4 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000001644 174.0
HKD1_k127_275630_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 568.0
HKD1_k127_275630_1 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 557.0
HKD1_k127_275630_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 496.0
HKD1_k127_275630_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 500.0
HKD1_k127_275630_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 421.0
HKD1_k127_275630_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009399 276.0
HKD1_k127_275630_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006841 276.0
HKD1_k127_275630_7 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000008014 151.0
HKD1_k127_275630_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000007426 85.0
HKD1_k127_2792774_0 Peptidase dimerisation domain - - - 1.81e-231 746.0
HKD1_k127_2792774_1 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 329.0
HKD1_k127_279837_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1720.0
HKD1_k127_279837_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1161.0
HKD1_k127_279837_10 UDP binding domain K13015 - 1.1.1.136 2.986e-212 667.0
HKD1_k127_279837_11 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 3.136e-205 657.0
HKD1_k127_279837_12 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.065e-204 649.0
HKD1_k127_279837_13 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 612.0
HKD1_k127_279837_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 594.0
HKD1_k127_279837_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 597.0
HKD1_k127_279837_16 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 580.0
HKD1_k127_279837_17 Sodium:dicarboxylate symporter family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 573.0
HKD1_k127_279837_18 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 552.0
HKD1_k127_279837_19 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 551.0
HKD1_k127_279837_2 TonB-dependent receptor - - - 0.0 1148.0
HKD1_k127_279837_20 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 545.0
HKD1_k127_279837_21 PFAM Bile acid sodium symporter K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 522.0
HKD1_k127_279837_22 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 503.0
HKD1_k127_279837_23 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 492.0
HKD1_k127_279837_24 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 465.0
HKD1_k127_279837_25 Mo-molybdopterin cofactor metabolic process K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 453.0
HKD1_k127_279837_26 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 449.0
HKD1_k127_279837_27 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 443.0
HKD1_k127_279837_28 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 422.0
HKD1_k127_279837_29 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 392.0
HKD1_k127_279837_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1030.0
HKD1_k127_279837_30 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 385.0
HKD1_k127_279837_31 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 386.0
HKD1_k127_279837_32 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 403.0
HKD1_k127_279837_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 374.0
HKD1_k127_279837_34 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 394.0
HKD1_k127_279837_35 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 336.0
HKD1_k127_279837_36 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
HKD1_k127_279837_37 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 324.0
HKD1_k127_279837_38 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 330.0
HKD1_k127_279837_39 FAD dependent oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 315.0
HKD1_k127_279837_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 6.218e-302 938.0
HKD1_k127_279837_40 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003931 297.0
HKD1_k127_279837_41 Psort location Cytoplasmic, score 8.96 K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002168 294.0
HKD1_k127_279837_42 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
HKD1_k127_279837_43 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002122 280.0
HKD1_k127_279837_44 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
HKD1_k127_279837_45 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008619 258.0
HKD1_k127_279837_46 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003882 255.0
HKD1_k127_279837_47 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD1_k127_279837_48 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
HKD1_k127_279837_49 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000002865 235.0
HKD1_k127_279837_5 Penicillin amidase K01434 - 3.5.1.11 6.817e-290 910.0
HKD1_k127_279837_50 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HKD1_k127_279837_51 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000131 225.0
HKD1_k127_279837_52 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
HKD1_k127_279837_53 - - - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
HKD1_k127_279837_54 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000003361 221.0
HKD1_k127_279837_55 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000001298 215.0
HKD1_k127_279837_56 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000002895 208.0
HKD1_k127_279837_57 Thioredoxin-like domain K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000001444 205.0
HKD1_k127_279837_58 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000001477 202.0
HKD1_k127_279837_59 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HKD1_k127_279837_6 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 6.887e-251 790.0
HKD1_k127_279837_60 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000001763 198.0
HKD1_k127_279837_61 - - - - 0.00000000000000000000000000000000000000000000000001019 186.0
HKD1_k127_279837_62 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000000000000001203 189.0
HKD1_k127_279837_63 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000005029 172.0
HKD1_k127_279837_64 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000002586 169.0
HKD1_k127_279837_65 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000004544 168.0
HKD1_k127_279837_66 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000004165 161.0
HKD1_k127_279837_67 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000006321 135.0
HKD1_k127_279837_68 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000008641 127.0
HKD1_k127_279837_69 - - - - 0.00000000000000000000000000000002641 127.0
HKD1_k127_279837_7 Fumarase C C-terminus K01744 - 4.3.1.1 3.455e-247 772.0
HKD1_k127_279837_70 - - - - 0.000000000000000000000000000009668 119.0
HKD1_k127_279837_71 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000001752 120.0
HKD1_k127_279837_73 - - - - 0.00000000000000000000000017 111.0
HKD1_k127_279837_75 Ribosomal protein L36 K02919 - - 0.0000000000000003651 78.0
HKD1_k127_279837_76 - - - - 0.0000002264 57.0
HKD1_k127_279837_8 Sodium:solute symporter family - - - 6.368e-227 712.0
HKD1_k127_279837_9 C-terminus of AA_permease K03294 - - 2.427e-221 696.0
HKD1_k127_2815377_0 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 482.0
HKD1_k127_2815377_1 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 402.0
HKD1_k127_2815377_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000034 116.0
HKD1_k127_2815377_11 transcriptional regulator - - - 0.0000000000000000000000000265 116.0
HKD1_k127_2815377_12 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000167 80.0
HKD1_k127_2815377_13 Ribosomal protein S21 K02970 - - 0.00000000000002088 75.0
HKD1_k127_2815377_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 302.0
HKD1_k127_2815377_3 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001494 275.0
HKD1_k127_2815377_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003297 248.0
HKD1_k127_2815377_5 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000001039 198.0
HKD1_k127_2815377_6 - - - - 0.0000000000000000000000000000000000000000000000000002596 196.0
HKD1_k127_2815377_7 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000009142 186.0
HKD1_k127_2815377_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000112 167.0
HKD1_k127_2815377_9 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000000000004937 135.0
HKD1_k127_283466_0 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 552.0
HKD1_k127_283466_1 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 523.0
HKD1_k127_283466_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 357.0
HKD1_k127_283466_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 294.0
HKD1_k127_283466_4 DinB family - - - 0.000000000000000000000000000000000000000000000000002836 189.0
HKD1_k127_2874139_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 479.0
HKD1_k127_2874139_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 374.0
HKD1_k127_2874139_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000007882 183.0
HKD1_k127_2874139_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000001566 172.0
HKD1_k127_2874139_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000003099 169.0
HKD1_k127_2874139_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000002141 153.0
HKD1_k127_2874139_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000008309 147.0
HKD1_k127_2874139_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000007276 147.0
HKD1_k127_2874139_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000001903 160.0
HKD1_k127_2874139_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004276 104.0
HKD1_k127_2874139_18 Ribosomal L29 protein K02904 - - 0.0000000000000003117 81.0
HKD1_k127_2874139_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
HKD1_k127_2874139_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 317.0
HKD1_k127_2874139_4 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 312.0
HKD1_k127_2874139_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 284.0
HKD1_k127_2874139_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 260.0
HKD1_k127_2874139_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000001694 237.0
HKD1_k127_2874139_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003652 224.0
HKD1_k127_2874139_9 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000005251 192.0
HKD1_k127_2949139_0 peptidyl-tyrosine sulfation - - - 8.749e-265 832.0
HKD1_k127_2949139_1 Putative glucoamylase - - - 9.757e-228 713.0
HKD1_k127_2949139_10 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000001109 212.0
HKD1_k127_2949139_11 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000002234 143.0
HKD1_k127_2949139_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000004371 126.0
HKD1_k127_2949139_14 hydroperoxide reductase activity - - - 0.0000000000000000000000000000731 122.0
HKD1_k127_2949139_15 - - - - 0.0000000000000000000000009137 121.0
HKD1_k127_2949139_17 - - - - 0.00000000001961 76.0
HKD1_k127_2949139_2 peptidyl-tyrosine sulfation - - - 3.837e-225 724.0
HKD1_k127_2949139_3 sigma factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 551.0
HKD1_k127_2949139_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 556.0
HKD1_k127_2949139_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 423.0
HKD1_k127_2949139_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 360.0
HKD1_k127_2949139_7 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 351.0
HKD1_k127_2949139_8 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 302.0
HKD1_k127_2949139_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 310.0
HKD1_k127_299769_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 509.0
HKD1_k127_299769_1 Penicillin amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 350.0
HKD1_k127_299769_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000412 138.0
HKD1_k127_3016878_0 - - - - 0.0 1155.0
HKD1_k127_3016878_1 succinyl-diaminopimelate desuccinylase activity - - - 1.497e-196 623.0
HKD1_k127_3016878_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000002229 214.0
HKD1_k127_3016878_11 YCII-related domain - - - 0.000000000000000000000000000000000000000000007944 167.0
HKD1_k127_3016878_12 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000001273 166.0
HKD1_k127_3016878_13 YCII-related domain - - - 0.0000000000000000000000000000000000000002372 152.0
HKD1_k127_3016878_14 - - - - 0.00000000000000000000000000000000004758 149.0
HKD1_k127_3016878_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000004363 140.0
HKD1_k127_3016878_16 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000012 130.0
HKD1_k127_3016878_17 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000002413 136.0
HKD1_k127_3016878_18 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000003577 124.0
HKD1_k127_3016878_19 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000002767 103.0
HKD1_k127_3016878_2 PFAM General substrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 552.0
HKD1_k127_3016878_20 SMART helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000001799 86.0
HKD1_k127_3016878_21 - - - - 0.00000000000000915 84.0
HKD1_k127_3016878_22 Protein of unknown function (DUF3592) - - - 0.000000004906 64.0
HKD1_k127_3016878_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 574.0
HKD1_k127_3016878_4 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 455.0
HKD1_k127_3016878_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
HKD1_k127_3016878_6 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 356.0
HKD1_k127_3016878_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002012 299.0
HKD1_k127_3016878_8 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005517 265.0
HKD1_k127_3016878_9 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
HKD1_k127_3033585_0 Zinc carboxypeptidase - - - 0.0 1406.0
HKD1_k127_3033585_1 Peptidase family M1 domain - - - 1.868e-295 919.0
HKD1_k127_3033585_10 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 516.0
HKD1_k127_3033585_11 RDD family K06384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 505.0
HKD1_k127_3033585_12 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 466.0
HKD1_k127_3033585_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 461.0
HKD1_k127_3033585_14 PFAM ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 424.0
HKD1_k127_3033585_15 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 398.0
HKD1_k127_3033585_16 DNA polymerase LigD, ligase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 407.0
HKD1_k127_3033585_17 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 382.0
HKD1_k127_3033585_18 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 342.0
HKD1_k127_3033585_19 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 333.0
HKD1_k127_3033585_2 Spermine/spermidine synthase domain - - - 3.38e-292 919.0
HKD1_k127_3033585_20 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
HKD1_k127_3033585_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001306 278.0
HKD1_k127_3033585_22 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003701 260.0
HKD1_k127_3033585_23 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HKD1_k127_3033585_24 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001255 271.0
HKD1_k127_3033585_25 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001087 268.0
HKD1_k127_3033585_26 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000001662 243.0
HKD1_k127_3033585_27 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
HKD1_k127_3033585_28 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HKD1_k127_3033585_29 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000006331 220.0
HKD1_k127_3033585_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.807e-287 916.0
HKD1_k127_3033585_30 Participates in the control of copper homeostasis K06201 - - 0.000000000000000000000000000000000000000000000000009136 196.0
HKD1_k127_3033585_32 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000131 166.0
HKD1_k127_3033585_33 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000424 168.0
HKD1_k127_3033585_34 Penicillinase repressor - - - 0.000000000000000000000000000000000000000001736 158.0
HKD1_k127_3033585_35 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000515 130.0
HKD1_k127_3033585_36 -acetyltransferase - - - 0.0000000000000000000000000000001003 142.0
HKD1_k127_3033585_37 Protein of unknown function (DUF3565) - - - 0.000000000000000000000008591 111.0
HKD1_k127_3033585_38 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001237 104.0
HKD1_k127_3033585_39 DEAD-like helicases superfamily - - - 0.0000000000000000000001684 109.0
HKD1_k127_3033585_4 cellulose binding - - - 8.535e-277 884.0
HKD1_k127_3033585_40 - - - - 0.00000000000000004441 83.0
HKD1_k127_3033585_42 pathogenesis K02417,K02519 - - 0.000000000003243 77.0
HKD1_k127_3033585_43 Bacterial Ig-like domain 2 - - - 0.000002973 57.0
HKD1_k127_3033585_44 Putative MetA-pathway of phenol degradation - - - 0.000005605 59.0
HKD1_k127_3033585_5 PFAM ABC transporter transmembrane K06147 - - 1.605e-266 835.0
HKD1_k127_3033585_6 MacB-like periplasmic core domain - - - 1.358e-231 745.0
HKD1_k127_3033585_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 587.0
HKD1_k127_3033585_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 583.0
HKD1_k127_3033585_9 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 537.0
HKD1_k127_3038211_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 312.0
HKD1_k127_3038211_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000004325 183.0
HKD1_k127_3055655_0 Collagenase K08303 - - 0.0 1135.0
HKD1_k127_3055655_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1050.0
HKD1_k127_3055655_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.942e-237 749.0
HKD1_k127_3055655_100 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.000000000000000000000000005427 118.0
HKD1_k127_3055655_101 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000051 108.0
HKD1_k127_3055655_102 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.000000000000000000000006286 102.0
HKD1_k127_3055655_103 Ribosomal L32p protein family K02911 - - 0.00000000000000000000001569 105.0
HKD1_k127_3055655_104 23S rRNA-intervening sequence protein - - - 0.00000000000000000182 91.0
HKD1_k127_3055655_105 - - - - 0.000000000000000006309 88.0
HKD1_k127_3055655_106 - - - - 0.00000000000000007447 89.0
HKD1_k127_3055655_107 ThiS family K03636 - - 0.000000000000002454 83.0
HKD1_k127_3055655_108 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05574,K05582 - 1.6.5.3 0.00000000000000953 79.0
HKD1_k127_3055655_109 PAP2 superfamily - - - 0.0000000001883 72.0
HKD1_k127_3055655_11 7TM receptor with intracellular HD hydrolase K07037 - - 1.288e-236 752.0
HKD1_k127_3055655_110 - - - - 0.0005356 50.0
HKD1_k127_3055655_12 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 3.409e-212 667.0
HKD1_k127_3055655_13 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 3.32e-206 650.0
HKD1_k127_3055655_14 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 5.888e-202 638.0
HKD1_k127_3055655_15 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.279e-201 634.0
HKD1_k127_3055655_16 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 7.676e-201 632.0
HKD1_k127_3055655_17 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 2.729e-195 618.0
HKD1_k127_3055655_18 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 595.0
HKD1_k127_3055655_19 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 588.0
HKD1_k127_3055655_2 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.063e-300 930.0
HKD1_k127_3055655_20 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 584.0
HKD1_k127_3055655_21 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 590.0
HKD1_k127_3055655_22 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 557.0
HKD1_k127_3055655_23 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 559.0
HKD1_k127_3055655_24 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 542.0
HKD1_k127_3055655_25 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 544.0
HKD1_k127_3055655_26 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
HKD1_k127_3055655_27 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 535.0
HKD1_k127_3055655_28 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 525.0
HKD1_k127_3055655_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 535.0
HKD1_k127_3055655_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 9.488e-293 920.0
HKD1_k127_3055655_30 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 535.0
HKD1_k127_3055655_31 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 516.0
HKD1_k127_3055655_32 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 503.0
HKD1_k127_3055655_33 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 488.0
HKD1_k127_3055655_34 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 491.0
HKD1_k127_3055655_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 492.0
HKD1_k127_3055655_36 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 499.0
HKD1_k127_3055655_37 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 472.0
HKD1_k127_3055655_38 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 492.0
HKD1_k127_3055655_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 472.0
HKD1_k127_3055655_4 RecQ zinc-binding K03654 - 3.6.4.12 1.752e-283 885.0
HKD1_k127_3055655_40 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 461.0
HKD1_k127_3055655_41 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 462.0
HKD1_k127_3055655_42 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 450.0
HKD1_k127_3055655_43 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 407.0
HKD1_k127_3055655_44 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 414.0
HKD1_k127_3055655_45 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 401.0
HKD1_k127_3055655_46 4Fe-4S binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 389.0
HKD1_k127_3055655_47 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 389.0
HKD1_k127_3055655_48 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 392.0
HKD1_k127_3055655_49 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 392.0
HKD1_k127_3055655_5 Carboxyl transferase domain - - - 2.234e-277 880.0
HKD1_k127_3055655_50 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 399.0
HKD1_k127_3055655_51 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 396.0
HKD1_k127_3055655_52 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 353.0
HKD1_k127_3055655_53 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 353.0
HKD1_k127_3055655_54 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 350.0
HKD1_k127_3055655_55 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
HKD1_k127_3055655_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HKD1_k127_3055655_57 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 341.0
HKD1_k127_3055655_58 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 334.0
HKD1_k127_3055655_59 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 337.0
HKD1_k127_3055655_6 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.559e-262 819.0
HKD1_k127_3055655_60 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 322.0
HKD1_k127_3055655_61 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 332.0
HKD1_k127_3055655_62 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
HKD1_k127_3055655_63 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 314.0
HKD1_k127_3055655_64 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 322.0
HKD1_k127_3055655_65 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 306.0
HKD1_k127_3055655_66 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD1_k127_3055655_67 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
HKD1_k127_3055655_68 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001886 286.0
HKD1_k127_3055655_69 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003186 283.0
HKD1_k127_3055655_7 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 2.442e-240 762.0
HKD1_k127_3055655_70 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 275.0
HKD1_k127_3055655_71 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005602 279.0
HKD1_k127_3055655_72 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001532 263.0
HKD1_k127_3055655_73 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006031 247.0
HKD1_k127_3055655_74 tRNA wobble adenosine to inosine editing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006924 253.0
HKD1_k127_3055655_75 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000005974 256.0
HKD1_k127_3055655_76 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000005993 231.0
HKD1_k127_3055655_77 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001296 229.0
HKD1_k127_3055655_78 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
HKD1_k127_3055655_79 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
HKD1_k127_3055655_8 Acyclic terpene utilisation family protein AtuA - - - 1.709e-239 762.0
HKD1_k127_3055655_80 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000007401 222.0
HKD1_k127_3055655_81 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000205 208.0
HKD1_k127_3055655_82 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000001045 210.0
HKD1_k127_3055655_83 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000009887 214.0
HKD1_k127_3055655_84 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000001394 210.0
HKD1_k127_3055655_85 - - - - 0.0000000000000000000000000000000000000000000000000000003484 195.0
HKD1_k127_3055655_86 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.0000000000000000000000000000000000000000000000000005948 196.0
HKD1_k127_3055655_87 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000000000004982 183.0
HKD1_k127_3055655_88 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000611 185.0
HKD1_k127_3055655_89 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000006146 183.0
HKD1_k127_3055655_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.393e-239 744.0
HKD1_k127_3055655_90 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000007604 170.0
HKD1_k127_3055655_91 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000004328 183.0
HKD1_k127_3055655_92 Ribosomal L27 protein K02899 - - 0.00000000000000000000000000000000000000003395 153.0
HKD1_k127_3055655_93 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000002818 151.0
HKD1_k127_3055655_94 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000002068 142.0
HKD1_k127_3055655_95 - - - - 0.000000000000000000000000000000000001347 153.0
HKD1_k127_3055655_96 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000003705 139.0
HKD1_k127_3055655_97 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000008743 133.0
HKD1_k127_3055655_98 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000001026 139.0
HKD1_k127_3055655_99 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000025 119.0
HKD1_k127_3072380_0 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000005676 176.0
HKD1_k127_3072380_1 Thiamine-binding protein - - - 0.00000000000022 79.0
HKD1_k127_3072380_2 Archease protein family (MTH1598/TM1083) - - - 0.0000007311 57.0
HKD1_k127_3085323_0 Penicillin amidase - - - 1.415e-279 871.0
HKD1_k127_3085323_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 5.277e-208 670.0
HKD1_k127_3085323_10 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000001605 259.0
HKD1_k127_3085323_11 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
HKD1_k127_3085323_12 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000003651 201.0
HKD1_k127_3085323_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000216 181.0
HKD1_k127_3085323_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001689 192.0
HKD1_k127_3085323_15 - - - - 0.0000000000000000000000000000000000000000000001486 179.0
HKD1_k127_3085323_16 - - - - 0.00000000000000000000000000000000000001202 148.0
HKD1_k127_3085323_17 DsrC like protein K11179 - - 0.0000000000000000000000000000000002241 134.0
HKD1_k127_3085323_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000001183 139.0
HKD1_k127_3085323_19 MacB-like periplasmic core domain - - - 0.0000000000000000000000004659 106.0
HKD1_k127_3085323_2 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 534.0
HKD1_k127_3085323_20 - - - - 0.0000000000000000000000008586 111.0
HKD1_k127_3085323_21 transport - - - 0.00000000000000001655 97.0
HKD1_k127_3085323_24 Bacterial Ig-like domain 2 - - - 0.000009134 59.0
HKD1_k127_3085323_25 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0003385 50.0
HKD1_k127_3085323_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 525.0
HKD1_k127_3085323_4 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 503.0
HKD1_k127_3085323_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 458.0
HKD1_k127_3085323_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 413.0
HKD1_k127_3085323_7 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HKD1_k127_3085323_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 355.0
HKD1_k127_3085323_9 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009226 239.0
HKD1_k127_3131412_0 Amidohydrolase family - - - 0.0 1648.0
HKD1_k127_3131412_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1454.0
HKD1_k127_3131412_10 stress-induced mitochondrial fusion - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
HKD1_k127_3131412_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 492.0
HKD1_k127_3131412_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 491.0
HKD1_k127_3131412_13 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 461.0
HKD1_k127_3131412_14 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 429.0
HKD1_k127_3131412_15 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 401.0
HKD1_k127_3131412_16 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 403.0
HKD1_k127_3131412_17 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 403.0
HKD1_k127_3131412_18 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 367.0
HKD1_k127_3131412_19 transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 357.0
HKD1_k127_3131412_2 CarboxypepD_reg-like domain K02014 - - 0.0 1166.0
HKD1_k127_3131412_20 BFD domain protein 2Fe-2S -binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 359.0
HKD1_k127_3131412_21 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 344.0
HKD1_k127_3131412_22 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 327.0
HKD1_k127_3131412_23 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 323.0
HKD1_k127_3131412_24 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 303.0
HKD1_k127_3131412_25 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 306.0
HKD1_k127_3131412_26 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004431 276.0
HKD1_k127_3131412_27 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 275.0
HKD1_k127_3131412_28 CheC-like family K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001112 272.0
HKD1_k127_3131412_29 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 261.0
HKD1_k127_3131412_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1010.0
HKD1_k127_3131412_30 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001215 259.0
HKD1_k127_3131412_31 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
HKD1_k127_3131412_32 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
HKD1_k127_3131412_33 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000003633 234.0
HKD1_k127_3131412_34 COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000002079 236.0
HKD1_k127_3131412_35 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004672 227.0
HKD1_k127_3131412_36 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000004526 214.0
HKD1_k127_3131412_37 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
HKD1_k127_3131412_38 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus K00125,K00441 - 1.12.98.1,1.17.1.9 0.000000000000000000000000000000000000000000000000000001319 210.0
HKD1_k127_3131412_39 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000001702 191.0
HKD1_k127_3131412_4 ERAP1-like C-terminal domain K01256 - 3.4.11.2 8.903e-305 957.0
HKD1_k127_3131412_40 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000004265 192.0
HKD1_k127_3131412_41 Nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000001539 183.0
HKD1_k127_3131412_42 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000008722 180.0
HKD1_k127_3131412_43 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000004995 175.0
HKD1_k127_3131412_44 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000004573 115.0
HKD1_k127_3131412_45 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000001214 109.0
HKD1_k127_3131412_47 PFAM CheW domain protein K03408 - - 0.0000000000000002093 86.0
HKD1_k127_3131412_49 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000489 63.0
HKD1_k127_3131412_5 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 1.352e-220 718.0
HKD1_k127_3131412_50 Domain of unknown function (DUF4388) - - - 0.000000005469 64.0
HKD1_k127_3131412_51 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.0005362 51.0
HKD1_k127_3131412_6 phosphoribosylamine-glycine ligase activity K01945 - 6.3.4.13 1.58e-201 635.0
HKD1_k127_3131412_7 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 589.0
HKD1_k127_3131412_8 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 536.0
HKD1_k127_3131412_9 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 531.0
HKD1_k127_3135875_0 TonB-dependent receptor K02014 - - 2.372e-281 892.0
HKD1_k127_3135875_1 efflux transmembrane transporter activity - - - 7.703e-228 725.0
HKD1_k127_3135875_2 Amidohydrolase - - - 1.483e-213 668.0
HKD1_k127_3135875_3 Sigma-70 region 2 - - - 1.998e-198 626.0
HKD1_k127_3135875_4 Protein of unknown function (DUF3761) - - - 0.00002441 53.0
HKD1_k127_3143499_0 cellulose binding - - - 0.0 1199.0
HKD1_k127_3143499_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 288.0
HKD1_k127_3143499_2 Protein of unknown function (DUF1207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005374 263.0
HKD1_k127_3143499_3 - - - - 0.000000000000000000282 101.0
HKD1_k127_3143499_4 - - - - 0.000000000008215 75.0
HKD1_k127_3144586_0 Efflux pump membrane transporter K18299 - - 4.192e-196 621.0
HKD1_k127_3144586_1 efflux transmembrane transporter activity K18300,K18308 - - 0.00000000000000000000000000000000000000000000000009373 185.0
HKD1_k127_3148048_0 efflux transmembrane transporter activity - - - 1.786e-305 957.0
HKD1_k127_3148048_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.789e-210 668.0
HKD1_k127_3148048_10 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 351.0
HKD1_k127_3148048_11 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 332.0
HKD1_k127_3148048_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
HKD1_k127_3148048_13 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000002708 239.0
HKD1_k127_3148048_14 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
HKD1_k127_3148048_15 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006508 235.0
HKD1_k127_3148048_16 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000007554 189.0
HKD1_k127_3148048_17 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000009571 177.0
HKD1_k127_3148048_18 DinB superfamily - - - 0.0000000000000000000000000000000000000000001394 174.0
HKD1_k127_3148048_19 cysteine-type peptidase activity K19224,K21471 - - 0.00000000000000000000000000000000000000004941 159.0
HKD1_k127_3148048_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 634.0
HKD1_k127_3148048_21 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.0000000000000000000000005827 121.0
HKD1_k127_3148048_22 Putative restriction endonuclease - - - 0.00000000000000000001572 102.0
HKD1_k127_3148048_23 PFAM blue (type 1) copper domain protein - - - 0.00000000000000007578 87.0
HKD1_k127_3148048_25 Bacterial Ig-like domain 2 - - - 0.00000000000002395 85.0
HKD1_k127_3148048_27 Domain of unknown function (DUF4143) K07133 - - 0.00000001613 60.0
HKD1_k127_3148048_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 567.0
HKD1_k127_3148048_4 Gluconate K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 529.0
HKD1_k127_3148048_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 508.0
HKD1_k127_3148048_6 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 465.0
HKD1_k127_3148048_7 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 430.0
HKD1_k127_3148048_8 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 395.0
HKD1_k127_3148048_9 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 369.0
HKD1_k127_3161164_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 515.0
HKD1_k127_3161164_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000007934 190.0
HKD1_k127_3169102_0 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002653 285.0
HKD1_k127_3169102_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000001117 96.0
HKD1_k127_3169102_2 Protein of unknown function (DUF2892) - - - 0.00000000009095 71.0
HKD1_k127_3171695_0 lysine biosynthetic process via aminoadipic acid - - - 2.056e-286 903.0
HKD1_k127_3171695_1 efflux transmembrane transporter activity - - - 4.178e-237 762.0
HKD1_k127_3171695_10 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000004049 134.0
HKD1_k127_3171695_11 CHAT domain - - - 0.0000000000000000000000000000005604 143.0
HKD1_k127_3171695_12 Domain of unknown function (DUF4386) - - - 0.000000000000009763 85.0
HKD1_k127_3171695_2 PFAM AMP-dependent synthetase and ligase - - - 1.629e-211 686.0
HKD1_k127_3171695_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 513.0
HKD1_k127_3171695_4 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 470.0
HKD1_k127_3171695_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 430.0
HKD1_k127_3171695_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 348.0
HKD1_k127_3171695_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007757 258.0
HKD1_k127_3171695_8 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001704 247.0
HKD1_k127_3171695_9 sigma factor activity K02405 - - 0.0000000000000000000000000000000000004146 151.0
HKD1_k127_3178606_0 cysteine protease - - - 1.655e-234 743.0
HKD1_k127_3178606_1 Amidase K01426 - 3.5.1.4 2.072e-216 682.0
HKD1_k127_3178606_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 542.0
HKD1_k127_3178606_3 peptidase K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 452.0
HKD1_k127_3178606_4 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000001334 181.0
HKD1_k127_3178606_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000002387 127.0
HKD1_k127_3184056_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.358e-254 795.0
HKD1_k127_3184056_1 Molybdopterin oxidoreductase K00123 - 1.17.1.9 7.406e-246 770.0
HKD1_k127_3184056_10 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000005082 225.0
HKD1_k127_3184056_11 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000021 174.0
HKD1_k127_3184056_12 - - - - 0.00000000000000000000000000000006662 128.0
HKD1_k127_3184056_13 Molybdopterin oxidoreductase - - - 0.0000000000000000000000000000001497 127.0
HKD1_k127_3184056_14 hydroperoxide reductase activity K01607 - 4.1.1.44 0.0000000000000000000000002594 108.0
HKD1_k127_3184056_2 Peptidase family M28 - - - 5.58e-230 726.0
HKD1_k127_3184056_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K18005 - 1.12.1.2,1.6.5.3 2.739e-229 734.0
HKD1_k127_3184056_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 550.0
HKD1_k127_3184056_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 500.0
HKD1_k127_3184056_6 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 427.0
HKD1_k127_3184056_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 420.0
HKD1_k127_3184056_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 370.0
HKD1_k127_3184056_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000001256 248.0
HKD1_k127_3190961_0 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 615.0
HKD1_k127_3190961_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 489.0
HKD1_k127_3190961_10 Type II secretion system (T2SS), protein M subtype b - - - 0.00003173 55.0
HKD1_k127_3190961_11 Peptidase propeptide and YPEB domain - - - 0.00006775 53.0
HKD1_k127_3190961_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 468.0
HKD1_k127_3190961_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003049 247.0
HKD1_k127_3190961_4 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000001822 210.0
HKD1_k127_3190961_5 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000006415 211.0
HKD1_k127_3190961_6 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000001091 202.0
HKD1_k127_3190961_7 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000008096 196.0
HKD1_k127_3190961_8 Type II secretion system protein K K02460 - - 0.000000000000000001906 100.0
HKD1_k127_3190961_9 PFAM Fimbrial assembly family protein K02461 - - 0.00002712 57.0
HKD1_k127_3201824_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.396e-250 791.0
HKD1_k127_3201824_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 314.0
HKD1_k127_3201824_2 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001917 280.0
HKD1_k127_3201824_3 - - - - 0.00000004005 59.0
HKD1_k127_3201824_4 Universal stress protein family - - - 0.000006047 57.0
HKD1_k127_3201824_5 6-phosphogluconolactonase activity - - - 0.000111 51.0
HKD1_k127_3228327_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1449.0
HKD1_k127_3228327_1 POT family K03305 - - 2.606e-214 676.0
HKD1_k127_3228327_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 439.0
HKD1_k127_3228327_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 318.0
HKD1_k127_3228327_12 Glycosyl transferase family 2 K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 289.0
HKD1_k127_3228327_13 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003805 279.0
HKD1_k127_3228327_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
HKD1_k127_3228327_15 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 268.0
HKD1_k127_3228327_16 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 259.0
HKD1_k127_3228327_17 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
HKD1_k127_3228327_18 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005311 248.0
HKD1_k127_3228327_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000004198 187.0
HKD1_k127_3228327_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 580.0
HKD1_k127_3228327_20 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000002604 183.0
HKD1_k127_3228327_21 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000004505 173.0
HKD1_k127_3228327_22 - - - - 0.0000000000000000000000000000004955 130.0
HKD1_k127_3228327_23 Carboxypeptidase regulatory-like domain - - - 0.00000000000000001587 86.0
HKD1_k127_3228327_3 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 558.0
HKD1_k127_3228327_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 552.0
HKD1_k127_3228327_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 539.0
HKD1_k127_3228327_6 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
HKD1_k127_3228327_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 486.0
HKD1_k127_3228327_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 494.0
HKD1_k127_3228327_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 473.0
HKD1_k127_3242879_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 598.0
HKD1_k127_3242879_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 523.0
HKD1_k127_3242879_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 445.0
HKD1_k127_3242879_3 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 398.0
HKD1_k127_3242879_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 374.0
HKD1_k127_3242879_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000009567 206.0
HKD1_k127_3242879_6 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000000113 116.0
HKD1_k127_3242879_7 - - - - 0.0000000000000000009716 94.0
HKD1_k127_3242879_8 Metallo-beta-lactamase superfamily - - - 0.0000000007819 62.0
HKD1_k127_3278291_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.104e-305 951.0
HKD1_k127_3278291_1 protein related to plant photosystem II stability assembly factor - - - 2.701e-219 686.0
HKD1_k127_3278291_10 - - - - 0.000000000000000000000000000000000001356 151.0
HKD1_k127_3278291_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000002307 138.0
HKD1_k127_3278291_2 Amidohydrolase family - - - 1.392e-201 644.0
HKD1_k127_3278291_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 580.0
HKD1_k127_3278291_4 2-dehydropantoate 2-reductase activity K00077,K01295 - 1.1.1.169,3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 448.0
HKD1_k127_3278291_5 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 404.0
HKD1_k127_3278291_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 366.0
HKD1_k127_3278291_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 349.0
HKD1_k127_3278291_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006842 286.0
HKD1_k127_3278291_9 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000005093 166.0
HKD1_k127_3290425_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 398.0
HKD1_k127_3290425_1 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002186 282.0
HKD1_k127_3290425_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 262.0
HKD1_k127_3290425_3 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000006921 263.0
HKD1_k127_3290425_4 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
HKD1_k127_3290425_5 - - - - 0.000000000000000000000000000000000000000002671 161.0
HKD1_k127_3290425_6 - - - - 0.00000008488 60.0
HKD1_k127_3332354_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003065 269.0
HKD1_k127_3332354_1 protein kinase activity - - - 0.0000000004472 65.0
HKD1_k127_3343027_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1084.0
HKD1_k127_3343027_1 protein secretion by the type I secretion system K11085 - - 9.269e-233 750.0
HKD1_k127_3343027_10 Domain of unknown function (DUF1906) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000602 289.0
HKD1_k127_3343027_11 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000007139 181.0
HKD1_k127_3343027_12 Carboxypeptidase regulatory-like domain - - - 0.00000001229 69.0
HKD1_k127_3343027_13 Peptidase dimerisation domain - - - 0.0000002077 52.0
HKD1_k127_3343027_2 Aminotransferase class-III K00822 - 2.6.1.18 1.082e-194 626.0
HKD1_k127_3343027_3 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 571.0
HKD1_k127_3343027_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 548.0
HKD1_k127_3343027_5 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 527.0
HKD1_k127_3343027_6 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 517.0
HKD1_k127_3343027_7 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 484.0
HKD1_k127_3343027_8 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 389.0
HKD1_k127_3343027_9 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 302.0
HKD1_k127_3417635_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000001509 258.0
HKD1_k127_3417635_1 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000003874 185.0
HKD1_k127_3417635_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000002172 182.0
HKD1_k127_3448054_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 453.0
HKD1_k127_3448054_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 423.0
HKD1_k127_3448054_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 411.0
HKD1_k127_3448054_3 FAD dependent oxidoreductase - - - 0.0000000000000000006596 87.0
HKD1_k127_3448054_4 23S rRNA-intervening sequence protein - - - 0.000009186 53.0
HKD1_k127_3451953_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.071e-257 807.0
HKD1_k127_3451953_1 PFAM RES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 307.0
HKD1_k127_3451953_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 299.0
HKD1_k127_3451953_3 Protein of unknown function (DUF4199) - - - 0.0000000000000000000000000000000000000000000000000000005183 199.0
HKD1_k127_3451953_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD1_k127_3451953_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000001015 173.0
HKD1_k127_3451953_7 Protein of unknown function (DUF2384) - - - 0.0000000004318 65.0
HKD1_k127_3487970_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.037e-316 978.0
HKD1_k127_3487970_1 efflux transmembrane transporter activity - - - 2.206e-223 720.0
HKD1_k127_3487970_10 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 332.0
HKD1_k127_3487970_11 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 322.0
HKD1_k127_3487970_12 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004747 246.0
HKD1_k127_3487970_13 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 238.0
HKD1_k127_3487970_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003631 235.0
HKD1_k127_3487970_15 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000006864 208.0
HKD1_k127_3487970_16 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
HKD1_k127_3487970_17 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000004816 194.0
HKD1_k127_3487970_18 - - - - 0.0000000000000000000000000000000000000000004244 163.0
HKD1_k127_3487970_19 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000004687 157.0
HKD1_k127_3487970_2 Helix-hairpin-helix motif K14162 - 2.7.7.7 4.197e-198 656.0
HKD1_k127_3487970_20 - - - - 0.000000000000000000000000000000000002194 149.0
HKD1_k127_3487970_21 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000001071 142.0
HKD1_k127_3487970_22 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001493 136.0
HKD1_k127_3487970_23 protein homotetramerization - - - 0.000000000000000000000000000000002198 139.0
HKD1_k127_3487970_24 PFAM GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000000000000000000000002947 138.0
HKD1_k127_3487970_25 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000000001656 132.0
HKD1_k127_3487970_26 - - - - 0.00000000000000000000000000000005555 136.0
HKD1_k127_3487970_27 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000002149 125.0
HKD1_k127_3487970_28 - - - - 0.000000000000000000000000000001388 127.0
HKD1_k127_3487970_29 - - - - 0.00000000000000000000000002206 113.0
HKD1_k127_3487970_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 589.0
HKD1_k127_3487970_30 - - - - 0.000000000000000006731 94.0
HKD1_k127_3487970_31 Flavin containing amine oxidoreductase - - - 0.0000000000008535 73.0
HKD1_k127_3487970_32 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000002371 73.0
HKD1_k127_3487970_33 energy transducer activity K03832 - - 0.0000000006638 71.0
HKD1_k127_3487970_34 Rad51 - - - 0.000000003017 67.0
HKD1_k127_3487970_35 - - - - 0.000000003201 64.0
HKD1_k127_3487970_36 Acid phosphatase homologues - - - 0.00000005271 65.0
HKD1_k127_3487970_37 Flavin containing amine oxidoreductase - - - 0.000404 47.0
HKD1_k127_3487970_4 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 454.0
HKD1_k127_3487970_5 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
HKD1_k127_3487970_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 413.0
HKD1_k127_3487970_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 391.0
HKD1_k127_3487970_8 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 374.0
HKD1_k127_3487970_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 342.0
HKD1_k127_3577135_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 376.0
HKD1_k127_3577135_2 - - - - 0.000002815 57.0
HKD1_k127_3636436_0 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 534.0
HKD1_k127_3636436_1 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000001104 61.0
HKD1_k127_3642529_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
HKD1_k127_3642529_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009222 265.0
HKD1_k127_3642529_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009892 243.0
HKD1_k127_3642529_3 - - - - 0.000000005574 58.0
HKD1_k127_3694434_0 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 273.0
HKD1_k127_3694434_1 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000001939 231.0
HKD1_k127_3694434_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000006405 125.0
HKD1_k127_3698625_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 483.0
HKD1_k127_3698625_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 408.0
HKD1_k127_3698625_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 380.0
HKD1_k127_3698625_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 353.0
HKD1_k127_3698625_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000172 253.0
HKD1_k127_3698625_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000005153 222.0
HKD1_k127_3698625_6 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.0000000000000000000000000000000000000000000000000000005333 196.0
HKD1_k127_3698625_7 Serine hydrolase (FSH1) - - - 0.000000000000000000000000000000000000000000000000000934 195.0
HKD1_k127_3698625_8 S4 RNA-binding domain K04762 - - 0.0000000000000000000000000000000008819 141.0
HKD1_k127_3698625_9 - - - - 0.000000000002724 74.0
HKD1_k127_3716356_0 belongs to the thioredoxin family K20543 - - 1.162e-295 926.0
HKD1_k127_3716356_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.954e-198 628.0
HKD1_k127_3716356_10 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 396.0
HKD1_k127_3716356_11 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 343.0
HKD1_k127_3716356_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 322.0
HKD1_k127_3716356_13 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 310.0
HKD1_k127_3716356_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 303.0
HKD1_k127_3716356_15 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 294.0
HKD1_k127_3716356_16 PFAM glycoside hydrolase, family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
HKD1_k127_3716356_17 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HKD1_k127_3716356_18 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
HKD1_k127_3716356_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
HKD1_k127_3716356_2 choline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 625.0
HKD1_k127_3716356_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
HKD1_k127_3716356_21 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
HKD1_k127_3716356_22 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000135 220.0
HKD1_k127_3716356_23 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003567 243.0
HKD1_k127_3716356_24 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001207 206.0
HKD1_k127_3716356_25 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000005038 205.0
HKD1_k127_3716356_26 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000001646 205.0
HKD1_k127_3716356_27 acetyltransferase K22441 - 2.3.1.57 0.000000000000000000000000000000000000000000000000006023 187.0
HKD1_k127_3716356_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002081 183.0
HKD1_k127_3716356_3 ThiF family K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 561.0
HKD1_k127_3716356_30 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000001387 178.0
HKD1_k127_3716356_31 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000001018 197.0
HKD1_k127_3716356_32 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000001712 179.0
HKD1_k127_3716356_33 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000003609 169.0
HKD1_k127_3716356_34 DinB family - - - 0.00000000000000000000000000000000000000000006281 166.0
HKD1_k127_3716356_35 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000004511 162.0
HKD1_k127_3716356_36 YjbR - - - 0.0000000000000000000000000000000000000000004886 161.0
HKD1_k127_3716356_37 acetyltransferase K03827 - - 0.000000000000000000000000000000000000000003758 160.0
HKD1_k127_3716356_38 - - - - 0.000000000000000000000000000000000000000007691 174.0
HKD1_k127_3716356_39 PFAM DsrE DsrF-like family K09004 - - 0.0000000000000000000000000000000000003033 145.0
HKD1_k127_3716356_4 Glycosyl hydrolase family 30 beta sandwich domain K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 569.0
HKD1_k127_3716356_40 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001238 145.0
HKD1_k127_3716356_41 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000001952 139.0
HKD1_k127_3716356_42 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000003296 133.0
HKD1_k127_3716356_43 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000001472 130.0
HKD1_k127_3716356_44 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000004112 129.0
HKD1_k127_3716356_45 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000002026 123.0
HKD1_k127_3716356_47 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004576 116.0
HKD1_k127_3716356_48 Domain of unknown function (DUF1508) K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000007697 114.0
HKD1_k127_3716356_49 hydroperoxide reductase activity - - - 0.0000000000000000000000007518 105.0
HKD1_k127_3716356_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 533.0
HKD1_k127_3716356_50 - - - - 0.0000000000000000000000027 109.0
HKD1_k127_3716356_51 domain, Protein - - - 0.0000000000000000000007712 109.0
HKD1_k127_3716356_52 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000001374 109.0
HKD1_k127_3716356_53 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000007763 95.0
HKD1_k127_3716356_54 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.00000000000000003291 87.0
HKD1_k127_3716356_55 Protein of unknown function, DUF481 K07283 - - 0.0000000000000001049 82.0
HKD1_k127_3716356_56 Poly(ADP-ribose) polymerase catalytic domain K10799 GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000723,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042393,GO:0042592,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901360,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252 2.4.2.30 0.00000000000000235 88.0
HKD1_k127_3716356_58 - - - - 0.00000000001645 68.0
HKD1_k127_3716356_59 lactoylglutathione lyase activity - - - 0.00000003199 62.0
HKD1_k127_3716356_6 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
HKD1_k127_3716356_60 Serine aminopeptidase, S33 K01055,K10216,K18092 - 3.1.1.24,3.7.1.9 0.0000002406 59.0
HKD1_k127_3716356_61 Predicted membrane protein (DUF2339) - - - 0.000001888 61.0
HKD1_k127_3716356_62 - - - - 0.0001126 49.0
HKD1_k127_3716356_63 - - - - 0.0001491 49.0
HKD1_k127_3716356_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 441.0
HKD1_k127_3716356_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 403.0
HKD1_k127_3716356_9 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 384.0
HKD1_k127_377226_0 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 381.0
HKD1_k127_377226_1 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 346.0
HKD1_k127_377226_2 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000001342 161.0
HKD1_k127_377226_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001226 125.0
HKD1_k127_377226_4 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000001305 125.0
HKD1_k127_377226_5 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000004512 76.0
HKD1_k127_377226_6 PKD domain - - - 0.0001167 55.0
HKD1_k127_3814629_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1373.0
HKD1_k127_3814629_1 Atp-dependent helicase - - - 0.0 1212.0
HKD1_k127_3814629_10 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 587.0
HKD1_k127_3814629_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 574.0
HKD1_k127_3814629_12 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 557.0
HKD1_k127_3814629_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 552.0
HKD1_k127_3814629_14 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 536.0
HKD1_k127_3814629_15 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 508.0
HKD1_k127_3814629_16 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 475.0
HKD1_k127_3814629_17 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 434.0
HKD1_k127_3814629_18 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 450.0
HKD1_k127_3814629_19 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 433.0
HKD1_k127_3814629_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1126.0
HKD1_k127_3814629_20 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 432.0
HKD1_k127_3814629_21 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 396.0
HKD1_k127_3814629_22 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 348.0
HKD1_k127_3814629_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 351.0
HKD1_k127_3814629_24 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 325.0
HKD1_k127_3814629_25 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
HKD1_k127_3814629_26 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003295 274.0
HKD1_k127_3814629_27 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000008478 260.0
HKD1_k127_3814629_28 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001916 255.0
HKD1_k127_3814629_29 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
HKD1_k127_3814629_3 Amidohydrolase family - - - 1.211e-266 831.0
HKD1_k127_3814629_30 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
HKD1_k127_3814629_31 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
HKD1_k127_3814629_32 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
HKD1_k127_3814629_33 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000003806 228.0
HKD1_k127_3814629_34 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000002711 205.0
HKD1_k127_3814629_35 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000397 207.0
HKD1_k127_3814629_36 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000000000000000000000000000000000000000002412 194.0
HKD1_k127_3814629_37 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000007803 189.0
HKD1_k127_3814629_38 - - - - 0.00000000000000000000000000000000000000000000000008483 186.0
HKD1_k127_3814629_39 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000004324 179.0
HKD1_k127_3814629_4 NAD synthase K01916 - 6.3.1.5 1.408e-259 812.0
HKD1_k127_3814629_40 acetyltransferase - - - 0.00000000000000000000000000000000000000000000004933 185.0
HKD1_k127_3814629_41 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000004915 167.0
HKD1_k127_3814629_42 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000006854 168.0
HKD1_k127_3814629_43 HNH nucleases - - - 0.0000000000000000000000000000000000000258 151.0
HKD1_k127_3814629_44 HNH nucleases - - - 0.00000000000000000000000000000000000002943 145.0
HKD1_k127_3814629_45 - - - - 0.00000000000000000000000000000000000005771 149.0
HKD1_k127_3814629_46 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000003716 152.0
HKD1_k127_3814629_47 - - - - 0.0000000000000000000000000000000001543 149.0
HKD1_k127_3814629_48 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000008458 143.0
HKD1_k127_3814629_49 Universal stress protein family - - - 0.000000000000000000000000000000002225 140.0
HKD1_k127_3814629_5 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.096e-255 818.0
HKD1_k127_3814629_50 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000002039 138.0
HKD1_k127_3814629_51 tRNA-binding protein K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000003256 136.0
HKD1_k127_3814629_52 - - - - 0.0000000000000000000000000000004404 126.0
HKD1_k127_3814629_53 - - - - 0.00000000000000000000000000003432 118.0
HKD1_k127_3814629_54 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000118 120.0
HKD1_k127_3814629_55 response to antibiotic - - - 0.00000000000000000000000000359 124.0
HKD1_k127_3814629_56 permease - - - 0.000000000000000000000000003848 124.0
HKD1_k127_3814629_57 - - - - 0.000000000000000000000001265 117.0
HKD1_k127_3814629_58 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000001055 105.0
HKD1_k127_3814629_59 Universal stress protein family - - - 0.00000000000000000003411 102.0
HKD1_k127_3814629_6 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 4.626e-240 760.0
HKD1_k127_3814629_60 - - - - 0.00000000000000000004539 94.0
HKD1_k127_3814629_61 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000008157 85.0
HKD1_k127_3814629_62 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000009097 85.0
HKD1_k127_3814629_63 Tfp pilus assembly protein FimT - - - 0.000000000000008309 80.0
HKD1_k127_3814629_64 - - - - 0.0000000000104 74.0
HKD1_k127_3814629_65 Rdx family K07401 - - 0.0000009819 52.0
HKD1_k127_3814629_66 - - - - 0.00002606 52.0
HKD1_k127_3814629_7 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 1.351e-197 635.0
HKD1_k127_3814629_8 Thiolase, C-terminal domain K00632 - 2.3.1.16 1.448e-195 624.0
HKD1_k127_3814629_9 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 588.0
HKD1_k127_394698_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 6.873e-215 677.0
HKD1_k127_394698_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 491.0
HKD1_k127_394698_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002804 276.0
HKD1_k127_394698_3 Globin - - - 0.00000000000000000000000000000000000000000000000001942 182.0
HKD1_k127_3977264_0 FAD binding domain K07077 - - 3.392e-299 924.0
HKD1_k127_3977264_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 509.0
HKD1_k127_3977264_2 Cytochrome c K12263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
HKD1_k127_3977264_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K09471 - - 0.00000000000000000000002074 103.0
HKD1_k127_3977264_4 - - - - 0.000008925 59.0
HKD1_k127_3977264_5 phosphorelay signal transduction system - - - 0.00001726 51.0
HKD1_k127_3994067_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 5.795e-318 986.0
HKD1_k127_3994067_1 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 475.0
HKD1_k127_3994067_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 423.0
HKD1_k127_3994067_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 349.0
HKD1_k127_3994067_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000005767 138.0
HKD1_k127_3994067_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000001299 126.0
HKD1_k127_3994067_6 - - - - 0.0000000000000000000000000001702 129.0
HKD1_k127_3994067_7 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000001319 115.0
HKD1_k127_3994067_8 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000004384 100.0
HKD1_k127_402230_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.0 1117.0
HKD1_k127_402230_1 Protein kinase domain K12132 - 2.7.11.1 3.217e-251 811.0
HKD1_k127_402230_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000006214 82.0
HKD1_k127_402230_2 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 391.0
HKD1_k127_402230_3 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 357.0
HKD1_k127_402230_4 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000001645 198.0
HKD1_k127_402230_5 luxR family - - - 0.000000000000000000000000000000000000000000005503 169.0
HKD1_k127_402230_6 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000001733 133.0
HKD1_k127_402230_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000001033 120.0
HKD1_k127_402230_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000001563 106.0
HKD1_k127_402230_9 - - - - 0.00000000000000000001225 100.0
HKD1_k127_4025882_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 426.0
HKD1_k127_4025882_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
HKD1_k127_4025882_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002827 271.0
HKD1_k127_4025882_3 Phosphate acyltransferases - - - 0.000000000000000000000004776 106.0
HKD1_k127_4025882_4 Phosphopantetheine attachment site - - - 0.00000000000001517 85.0
HKD1_k127_4045643_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1034.0
HKD1_k127_4045643_1 protein histidine kinase activity K03407,K07678 - 2.7.13.3 9.774e-279 877.0
HKD1_k127_4045643_10 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 351.0
HKD1_k127_4045643_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 371.0
HKD1_k127_4045643_12 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
HKD1_k127_4045643_13 Domain of unknown function (DUF4249) - - - 0.000000000000000000000000000000000000000000000000000000000002307 224.0
HKD1_k127_4045643_14 - - - - 0.00000000000000000000000000000000000000000000000000006187 203.0
HKD1_k127_4045643_15 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000137 169.0
HKD1_k127_4045643_16 - - - - 0.000000000000000000000000000000000000003641 158.0
HKD1_k127_4045643_18 - - - - 0.0000000000000000000002992 109.0
HKD1_k127_4045643_19 phosphorelay signal transduction system - - - 0.00000006915 55.0
HKD1_k127_4045643_2 Carboxypeptidase regulatory-like domain - - - 6.172e-207 694.0
HKD1_k127_4045643_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 556.0
HKD1_k127_4045643_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 495.0
HKD1_k127_4045643_5 heat shock protein binding K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 439.0
HKD1_k127_4045643_6 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 456.0
HKD1_k127_4045643_7 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 439.0
HKD1_k127_4045643_8 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
HKD1_k127_4045643_9 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 363.0
HKD1_k127_407134_0 Zinc carboxypeptidase - - - 3.506e-309 968.0
HKD1_k127_407134_1 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 2.305e-283 893.0
HKD1_k127_407134_2 cellulose binding - - - 9.978e-248 780.0
HKD1_k127_407134_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 392.0
HKD1_k127_407134_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 359.0
HKD1_k127_407134_5 Matrixin - - - 0.00000000000000000000000000000000000000000000004389 179.0
HKD1_k127_407134_6 PRC-barrel domain - - - 0.000001508 59.0
HKD1_k127_407134_7 Transposase - - - 0.00002858 55.0
HKD1_k127_4075269_0 peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 593.0
HKD1_k127_4075269_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 524.0
HKD1_k127_4075269_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003404 284.0
HKD1_k127_4075269_3 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000002093 254.0
HKD1_k127_4075269_4 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000007253 163.0
HKD1_k127_4096160_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1485.0
HKD1_k127_4096160_1 serine-type peptidase activity - - - 1.013e-283 897.0
HKD1_k127_4096160_10 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 442.0
HKD1_k127_4096160_11 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
HKD1_k127_4096160_12 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 344.0
HKD1_k127_4096160_13 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
HKD1_k127_4096160_14 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
HKD1_k127_4096160_15 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 325.0
HKD1_k127_4096160_16 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 301.0
HKD1_k127_4096160_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001337 278.0
HKD1_k127_4096160_18 Cytochrome C oxidase, cbb3-type, subunit III K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
HKD1_k127_4096160_19 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000004607 252.0
HKD1_k127_4096160_2 ABC transporter transmembrane region K18890 - - 1.16e-238 752.0
HKD1_k127_4096160_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000002258 228.0
HKD1_k127_4096160_21 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000000001567 194.0
HKD1_k127_4096160_22 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000001624 189.0
HKD1_k127_4096160_23 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_4096160_24 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000001556 185.0
HKD1_k127_4096160_25 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000001735 176.0
HKD1_k127_4096160_26 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000002667 156.0
HKD1_k127_4096160_27 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000006069 152.0
HKD1_k127_4096160_28 Protein conserved in bacteria - - - 0.00000000000000000000000000000000001128 152.0
HKD1_k127_4096160_29 DNA-binding transcription factor activity - - - 0.000000000000000000000000004582 123.0
HKD1_k127_4096160_3 PFAM Protein kinase domain - - - 1.116e-217 711.0
HKD1_k127_4096160_30 Transglycosylase associated protein - - - 0.00000000000000000000003453 115.0
HKD1_k127_4096160_31 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000004304 102.0
HKD1_k127_4096160_32 PFAM Transglycosylase-associated protein - - - 0.000000000000000000007138 95.0
HKD1_k127_4096160_33 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.000000000003105 78.0
HKD1_k127_4096160_34 - - - - 0.0000000000075 73.0
HKD1_k127_4096160_35 - - - - 0.0000000007183 72.0
HKD1_k127_4096160_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 585.0
HKD1_k127_4096160_5 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 501.0
HKD1_k127_4096160_6 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 498.0
HKD1_k127_4096160_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 448.0
HKD1_k127_4096160_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 436.0
HKD1_k127_4096160_9 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 430.0
HKD1_k127_4108157_0 MMPL family - - - 9.545e-285 912.0
HKD1_k127_4108157_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003004 265.0
HKD1_k127_4108157_2 cellulase activity - - - 0.000000000001893 80.0
HKD1_k127_4108157_3 Ricin-type beta-trefoil - - - 0.0000000006569 71.0
HKD1_k127_4108157_4 Ricin-type beta-trefoil - - - 0.00000001459 67.0
HKD1_k127_4136553_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000001456 122.0
HKD1_k127_4136553_1 Bacterial Ig-like domain 2 - - - 0.0000000000000000002507 103.0
HKD1_k127_4136553_2 Helix-turn-helix domain - - - 0.000000000003297 74.0
HKD1_k127_4136553_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00009022 55.0
HKD1_k127_4145724_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1053.0
HKD1_k127_4145724_1 Sortilin, neurotensin receptor 3, - - - 7.85e-255 796.0
HKD1_k127_4145724_2 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.0000000000000000000000000000001148 125.0
HKD1_k127_4176985_0 Cytochrome c-type biogenesis protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 607.0
HKD1_k127_4176985_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
HKD1_k127_4176985_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000001161 144.0
HKD1_k127_4176985_3 CcmB protein K02194 - - 0.0000000000001088 74.0
HKD1_k127_4176985_4 TIGRFAM periplasmic protein K02199 - - 0.00000000002236 75.0
HKD1_k127_4212566_0 esterase - - - 2.621e-215 670.0
HKD1_k127_4212566_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 574.0
HKD1_k127_4212566_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 543.0
HKD1_k127_4212566_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004675 255.0
HKD1_k127_4222246_0 Elongation factor G C-terminus K06207 - - 2.23e-315 977.0
HKD1_k127_4222246_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.371e-248 780.0
HKD1_k127_4222246_10 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 324.0
HKD1_k127_4222246_11 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 324.0
HKD1_k127_4222246_12 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 317.0
HKD1_k127_4222246_13 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000006481 256.0
HKD1_k127_4222246_15 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000001626 133.0
HKD1_k127_4222246_17 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000002401 90.0
HKD1_k127_4222246_18 - - - - 0.00000000000001992 75.0
HKD1_k127_4222246_19 - - - - 0.0000000001822 73.0
HKD1_k127_4222246_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.1e-220 726.0
HKD1_k127_4222246_20 cell adhesion involved in biofilm formation - - - 0.00002849 57.0
HKD1_k127_4222246_3 ABC transporter transmembrane region K11085 - - 1.574e-201 644.0
HKD1_k127_4222246_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 521.0
HKD1_k127_4222246_5 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 512.0
HKD1_k127_4222246_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 411.0
HKD1_k127_4222246_7 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
HKD1_k127_4222246_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 367.0
HKD1_k127_4222246_9 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 353.0
HKD1_k127_4232091_0 chaperone-mediated protein folding - - - 1.319e-210 667.0
HKD1_k127_4232091_1 peptidase K01415,K07386 - 3.4.24.71 9.527e-197 632.0
HKD1_k127_4232091_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 502.0
HKD1_k127_4232091_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 503.0
HKD1_k127_4232091_4 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 302.0
HKD1_k127_4232091_5 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000005105 237.0
HKD1_k127_4232091_6 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000004763 177.0
HKD1_k127_4242071_0 cellulose binding - - - 2.63e-313 996.0
HKD1_k127_4242071_1 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000001187 130.0
HKD1_k127_4242071_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000007453 127.0
HKD1_k127_4242071_3 Beta-lactamase - - - 0.00007561 54.0
HKD1_k127_428644_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1394.0
HKD1_k127_428644_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 546.0
HKD1_k127_428644_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 431.0
HKD1_k127_428644_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 424.0
HKD1_k127_428644_12 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 409.0
HKD1_k127_428644_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HKD1_k127_428644_14 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 374.0
HKD1_k127_428644_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 343.0
HKD1_k127_428644_16 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 324.0
HKD1_k127_428644_17 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 327.0
HKD1_k127_428644_18 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 306.0
HKD1_k127_428644_19 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001652 285.0
HKD1_k127_428644_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 492.0
HKD1_k127_428644_20 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005535 254.0
HKD1_k127_428644_21 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
HKD1_k127_428644_22 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002533 221.0
HKD1_k127_428644_23 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000004201 208.0
HKD1_k127_428644_24 NlpC/P60 family - - - 0.000000000000000000000000000000000000000003716 162.0
HKD1_k127_428644_25 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000005197 166.0
HKD1_k127_428644_27 Belongs to the globin family - - - 0.00000000000000000000000000000000000001693 150.0
HKD1_k127_428644_28 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000001645 132.0
HKD1_k127_428644_29 YMGG-like Gly-zipper - - - 0.00000000000000000000000253 108.0
HKD1_k127_428644_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 480.0
HKD1_k127_428644_30 Redoxin - - - 0.00000000000000000004927 93.0
HKD1_k127_428644_31 Alpha beta hydrolase K01066 - - 0.0000000000002133 76.0
HKD1_k127_428644_32 Redoxin - - - 0.00000000008326 66.0
HKD1_k127_428644_4 cystathionine K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 496.0
HKD1_k127_428644_5 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 483.0
HKD1_k127_428644_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 455.0
HKD1_k127_428644_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 459.0
HKD1_k127_428644_8 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 453.0
HKD1_k127_428644_9 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 454.0
HKD1_k127_4289408_0 Carboxypeptidase regulatory-like domain - - - 0.0 1112.0
HKD1_k127_4289408_1 Protein kinase domain K12132 - 2.7.11.1 3.128e-247 800.0
HKD1_k127_4289408_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
HKD1_k127_4289408_11 - - - - 0.00000000000000000000000000000000000000000000000000000006974 206.0
HKD1_k127_4289408_12 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000007008 201.0
HKD1_k127_4289408_13 - - - - 0.000000000000000000000000000000000000000000000000000001176 198.0
HKD1_k127_4289408_14 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000001949 184.0
HKD1_k127_4289408_15 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000004101 169.0
HKD1_k127_4289408_16 transport - - - 0.000000000000000000000000000000000456 145.0
HKD1_k127_4289408_17 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000007295 124.0
HKD1_k127_4289408_19 cysteine-type peptidase activity K19224,K21471 - - 0.00000003876 63.0
HKD1_k127_4289408_2 efflux transmembrane transporter activity - - - 1.902e-231 741.0
HKD1_k127_4289408_20 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0002536 52.0
HKD1_k127_4289408_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 568.0
HKD1_k127_4289408_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 569.0
HKD1_k127_4289408_5 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 580.0
HKD1_k127_4289408_6 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 445.0
HKD1_k127_4289408_7 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 336.0
HKD1_k127_4289408_8 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007669 286.0
HKD1_k127_4289408_9 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005142 261.0
HKD1_k127_4373122_0 Bacterial membrane protein YfhO - - - 1.029e-261 829.0
HKD1_k127_4373122_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 3.178e-260 809.0
HKD1_k127_4373122_10 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 364.0
HKD1_k127_4373122_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 324.0
HKD1_k127_4373122_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 304.0
HKD1_k127_4373122_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
HKD1_k127_4373122_14 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000001906 213.0
HKD1_k127_4373122_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000002958 207.0
HKD1_k127_4373122_16 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000006347 203.0
HKD1_k127_4373122_17 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000004933 185.0
HKD1_k127_4373122_18 acr, cog1993 K09137 - - 0.0000000000000000000000000000000000000000000001259 173.0
HKD1_k127_4373122_19 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000009464 161.0
HKD1_k127_4373122_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.386e-212 668.0
HKD1_k127_4373122_20 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000001074 133.0
HKD1_k127_4373122_21 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000001006 119.0
HKD1_k127_4373122_22 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000008049 83.0
HKD1_k127_4373122_3 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 591.0
HKD1_k127_4373122_4 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 490.0
HKD1_k127_4373122_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
HKD1_k127_4373122_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 423.0
HKD1_k127_4373122_7 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 422.0
HKD1_k127_4373122_8 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 406.0
HKD1_k127_4373122_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 378.0
HKD1_k127_4388786_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.0000000000000000000000000000000000006671 142.0
HKD1_k127_4388786_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000001044 138.0
HKD1_k127_4388786_2 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000003402 145.0
HKD1_k127_4388786_4 PFAM Helix-turn-helix K07729 - - 0.00000000006531 63.0
HKD1_k127_4388786_5 Regulator of cell autolysis - - - 0.00000001896 67.0
HKD1_k127_4407748_0 amine dehydrogenase activity K17285 - - 6.023e-261 810.0
HKD1_k127_4407748_1 Sugar (and other) transporter - - - 1.131e-206 655.0
HKD1_k127_4407748_2 PFAM AMP-dependent synthetase and ligase K12429,K18660,K18661,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 600.0
HKD1_k127_4407748_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 551.0
HKD1_k127_4407748_4 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 490.0
HKD1_k127_4407748_5 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 377.0
HKD1_k127_4407748_6 tRNA m6t6A37 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000182 234.0
HKD1_k127_4407748_7 - - - - 0.00000000000000000000000000000000000000000000000000000002363 207.0
HKD1_k127_4407748_9 Protein of unknown function (DUF3455) - - - 0.0000000000000000000001593 106.0
HKD1_k127_4421364_0 Gamma-glutamyltranspeptidase - - - 0.0 1122.0
HKD1_k127_4421364_1 MacB-like periplasmic core domain - - - 5.399e-240 772.0
HKD1_k127_4421364_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 555.0
HKD1_k127_4421364_11 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 544.0
HKD1_k127_4421364_12 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 505.0
HKD1_k127_4421364_13 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 517.0
HKD1_k127_4421364_14 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 447.0
HKD1_k127_4421364_15 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 431.0
HKD1_k127_4421364_16 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 422.0
HKD1_k127_4421364_17 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 409.0
HKD1_k127_4421364_18 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
HKD1_k127_4421364_19 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
HKD1_k127_4421364_2 PFAM Circadian clock protein KaiC central region K08482 - - 4.786e-227 721.0
HKD1_k127_4421364_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 318.0
HKD1_k127_4421364_21 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 306.0
HKD1_k127_4421364_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 302.0
HKD1_k127_4421364_23 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 262.0
HKD1_k127_4421364_24 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
HKD1_k127_4421364_25 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HKD1_k127_4421364_26 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002691 257.0
HKD1_k127_4421364_27 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000006728 190.0
HKD1_k127_4421364_29 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000006798 176.0
HKD1_k127_4421364_3 Amidohydrolase family K06015 - 3.5.1.81 2.908e-216 692.0
HKD1_k127_4421364_30 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000002487 163.0
HKD1_k127_4421364_31 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000000000000000000000000002176 161.0
HKD1_k127_4421364_32 - - - - 0.00000000000000000000000000000008184 140.0
HKD1_k127_4421364_33 KaiB K08481 - - 0.00000000000000000000000000001108 123.0
HKD1_k127_4421364_34 - - - - 0.0000000000000000832 83.0
HKD1_k127_4421364_35 - - - - 0.00000000000004811 79.0
HKD1_k127_4421364_37 Helix-turn-helix domain - - - 0.000000000008799 69.0
HKD1_k127_4421364_39 - - - - 0.00000002131 62.0
HKD1_k127_4421364_4 efflux transmembrane transporter activity K02004 - - 8.921e-194 636.0
HKD1_k127_4421364_40 Protein kinase domain K12132 - 2.7.11.1 0.0003695 46.0
HKD1_k127_4421364_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 610.0
HKD1_k127_4421364_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 605.0
HKD1_k127_4421364_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 582.0
HKD1_k127_4421364_8 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 597.0
HKD1_k127_4421364_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 587.0
HKD1_k127_4423724_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.89e-203 641.0
HKD1_k127_4423724_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 598.0
HKD1_k127_4423724_10 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 364.0
HKD1_k127_4423724_11 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 341.0
HKD1_k127_4423724_12 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 359.0
HKD1_k127_4423724_13 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
HKD1_k127_4423724_14 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 342.0
HKD1_k127_4423724_15 efflux transmembrane transporter activity K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 331.0
HKD1_k127_4423724_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 319.0
HKD1_k127_4423724_17 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 311.0
HKD1_k127_4423724_18 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009431 293.0
HKD1_k127_4423724_19 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009883 273.0
HKD1_k127_4423724_2 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 534.0
HKD1_k127_4423724_20 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003449 261.0
HKD1_k127_4423724_21 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003298 253.0
HKD1_k127_4423724_22 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
HKD1_k127_4423724_23 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000002401 238.0
HKD1_k127_4423724_24 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000000000004051 195.0
HKD1_k127_4423724_25 - - - - 0.0000000000000000000000000000000000000000000000008514 185.0
HKD1_k127_4423724_26 - - - - 0.00000000000000000000000000000000000000002391 172.0
HKD1_k127_4423724_27 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000000000000000005726 147.0
HKD1_k127_4423724_28 PAS domain - - - 0.0000000000000000000000000007846 131.0
HKD1_k127_4423724_29 Binds the 23S rRNA K02909 - - 0.000000000000000000000003604 110.0
HKD1_k127_4423724_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 521.0
HKD1_k127_4423724_31 AAA ATPase domain - - - 0.00000000000000000002214 98.0
HKD1_k127_4423724_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 518.0
HKD1_k127_4423724_5 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 508.0
HKD1_k127_4423724_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 484.0
HKD1_k127_4423724_7 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 482.0
HKD1_k127_4423724_8 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 391.0
HKD1_k127_4423724_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HKD1_k127_44713_0 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 1.794e-225 720.0
HKD1_k127_44713_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 471.0
HKD1_k127_44713_10 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001553 259.0
HKD1_k127_44713_11 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000001638 252.0
HKD1_k127_44713_12 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004884 246.0
HKD1_k127_44713_13 DoxX - - - 0.0000000000000000000000000000000000000000000000000000000000000002691 229.0
HKD1_k127_44713_14 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000007627 203.0
HKD1_k127_44713_15 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000003103 191.0
HKD1_k127_44713_16 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000004419 157.0
HKD1_k127_44713_17 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000001165 139.0
HKD1_k127_44713_18 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000002139 128.0
HKD1_k127_44713_19 - - - - 0.0000000000000000000000006979 115.0
HKD1_k127_44713_2 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 454.0
HKD1_k127_44713_20 Lysin motif - - - 0.0000000000000000002962 99.0
HKD1_k127_44713_21 lyase activity - - - 0.000002038 61.0
HKD1_k127_44713_22 HEAT repeats - - - 0.000006164 59.0
HKD1_k127_44713_23 - - - - 0.0004972 46.0
HKD1_k127_44713_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 455.0
HKD1_k127_44713_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 435.0
HKD1_k127_44713_5 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 451.0
HKD1_k127_44713_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 402.0
HKD1_k127_44713_7 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 396.0
HKD1_k127_44713_8 peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 351.0
HKD1_k127_44713_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
HKD1_k127_4476945_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.103e-299 944.0
HKD1_k127_4476945_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.421e-226 714.0
HKD1_k127_4476945_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
HKD1_k127_4479779_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1364.0
HKD1_k127_4479779_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.431e-236 736.0
HKD1_k127_4479779_2 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 299.0
HKD1_k127_4479779_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000002136 178.0
HKD1_k127_4479779_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000004534 173.0
HKD1_k127_4479779_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000655 52.0
HKD1_k127_4506334_0 PglZ domain - - - 1.603e-243 762.0
HKD1_k127_4506334_1 Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 560.0
HKD1_k127_4506334_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 539.0
HKD1_k127_4506334_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 336.0
HKD1_k127_4506334_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
HKD1_k127_4506334_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000001204 248.0
HKD1_k127_4506334_6 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000003194 235.0
HKD1_k127_4506334_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000004041 115.0
HKD1_k127_4506334_8 - - - - 0.00000000000000000007033 95.0
HKD1_k127_4531832_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 481.0
HKD1_k127_4531832_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 413.0
HKD1_k127_4544942_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 344.0
HKD1_k127_4544942_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 291.0
HKD1_k127_4544942_2 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000000000000000000000000000000000000000000006218 238.0
HKD1_k127_4544942_3 FAD dependent oxidoreductase K19813 - 1.1.5.9 0.000000000000000000000000000000000000000000000000003989 195.0
HKD1_k127_4544942_4 Thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000000002589 196.0
HKD1_k127_4544942_5 - - - - 0.0000000000000000000000000000000000009297 146.0
HKD1_k127_4544942_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001638 131.0
HKD1_k127_4544942_7 - - - - 0.00000000000000000000000000009119 127.0
HKD1_k127_4544942_8 Domain of unknown function (DUF2382) - - - 0.000000000000000116 87.0
HKD1_k127_4544942_9 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.0000000002157 75.0
HKD1_k127_456630_0 Sortilin, neurotensin receptor 3, - - - 0.0 1667.0
HKD1_k127_456630_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 5e-324 1013.0
HKD1_k127_456630_10 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 323.0
HKD1_k127_456630_11 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002525 282.0
HKD1_k127_456630_12 PFAM Cache K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000169 242.0
HKD1_k127_456630_13 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000002135 214.0
HKD1_k127_456630_14 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000009523 196.0
HKD1_k127_456630_15 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000004583 176.0
HKD1_k127_456630_16 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000000000000000000000487 173.0
HKD1_k127_456630_18 copper resistance D domain protein K14166 - - 0.000000000000000000000000000001266 138.0
HKD1_k127_456630_19 GntR family transcriptional regulator K15977 - - 0.0000000000000000000000000008894 125.0
HKD1_k127_456630_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.222e-288 899.0
HKD1_k127_456630_20 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000002243 112.0
HKD1_k127_456630_21 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000008461 99.0
HKD1_k127_456630_22 DUF167 K09131 - - 0.00000000000000007426 91.0
HKD1_k127_456630_23 transmembrane signaling receptor activity K03406 - - 0.00000001289 68.0
HKD1_k127_456630_24 - - - - 0.000006916 54.0
HKD1_k127_456630_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 2.615e-249 776.0
HKD1_k127_456630_4 von Willebrand factor (vWF) type A domain - - - 2.719e-218 686.0
HKD1_k127_456630_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 540.0
HKD1_k127_456630_6 peptidase S9 prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 553.0
HKD1_k127_456630_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 395.0
HKD1_k127_456630_8 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 396.0
HKD1_k127_456630_9 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 355.0
HKD1_k127_4625161_0 ASPIC UnbV domain protein - - - 4.124e-271 848.0
HKD1_k127_4625161_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 573.0
HKD1_k127_4625161_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 518.0
HKD1_k127_4625161_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 336.0
HKD1_k127_4625161_4 - - - - 0.000000000000000000000000000000008492 135.0
HKD1_k127_4641497_0 Carbohydrate family 9 binding domain-like - - - 4.089e-255 815.0
HKD1_k127_4641497_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 6.019e-214 672.0
HKD1_k127_4641497_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 381.0
HKD1_k127_4641497_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HKD1_k127_4641497_12 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 396.0
HKD1_k127_4641497_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 365.0
HKD1_k127_4641497_14 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 312.0
HKD1_k127_4641497_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
HKD1_k127_4641497_16 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 293.0
HKD1_k127_4641497_17 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 289.0
HKD1_k127_4641497_18 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002471 275.0
HKD1_k127_4641497_19 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000008242 246.0
HKD1_k127_4641497_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 7.871e-208 664.0
HKD1_k127_4641497_20 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
HKD1_k127_4641497_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004811 253.0
HKD1_k127_4641497_22 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000009854 204.0
HKD1_k127_4641497_23 SURF1 family K14998 - - 0.00000000000000000000000000000000000000000000000000001106 212.0
HKD1_k127_4641497_24 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000003196 190.0
HKD1_k127_4641497_25 NUDIX domain - - - 0.00000000000000000000000000000000000000000004571 167.0
HKD1_k127_4641497_27 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000001304 148.0
HKD1_k127_4641497_29 Penicillinase repressor - - - 0.000000000000000000000000000000000953 140.0
HKD1_k127_4641497_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 614.0
HKD1_k127_4641497_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000001636 132.0
HKD1_k127_4641497_31 Rhodanese Homology Domain - - - 0.00000000000000000000000000000004677 139.0
HKD1_k127_4641497_32 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000117 119.0
HKD1_k127_4641497_33 General stress protein K06884 - - 0.00000000000000000002538 100.0
HKD1_k127_4641497_34 Domain of unknown function (DUF4383) - - - 0.0000000000000000005895 94.0
HKD1_k127_4641497_35 - - - - 0.000000000000000001153 98.0
HKD1_k127_4641497_36 Domain of unknown function (DUF4383) - - - 0.000000000000000003649 98.0
HKD1_k127_4641497_38 Heavy-metal-associated domain K07213 - - 0.000000000001358 70.0
HKD1_k127_4641497_39 Heavy-metal-associated domain - - - 0.000000000748 62.0
HKD1_k127_4641497_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 570.0
HKD1_k127_4641497_40 PBS lyase HEAT-like repeat - - - 0.00007612 53.0
HKD1_k127_4641497_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 557.0
HKD1_k127_4641497_6 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 514.0
HKD1_k127_4641497_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 445.0
HKD1_k127_4641497_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 431.0
HKD1_k127_4641497_9 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 407.0
HKD1_k127_4682002_0 Aldehyde dehydrogenase family K00138 - - 8.225e-275 850.0
HKD1_k127_4682002_1 Amidohydrolase family - - - 5.165e-222 700.0
HKD1_k127_4682002_10 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 375.0
HKD1_k127_4682002_11 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 356.0
HKD1_k127_4682002_12 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 339.0
HKD1_k127_4682002_13 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 348.0
HKD1_k127_4682002_14 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 294.0
HKD1_k127_4682002_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
HKD1_k127_4682002_16 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003859 258.0
HKD1_k127_4682002_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005813 252.0
HKD1_k127_4682002_18 aminotransferase K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000001239 211.0
HKD1_k127_4682002_19 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000001629 205.0
HKD1_k127_4682002_2 efflux transmembrane transporter activity - - - 4.893e-213 690.0
HKD1_k127_4682002_20 - - - - 0.00000000000000000000000000000000000000000000000001178 186.0
HKD1_k127_4682002_21 cobalamin-transporting ATPase activity K02014 - - 0.0000000000000000000000000000000000000000002068 182.0
HKD1_k127_4682002_22 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000002541 171.0
HKD1_k127_4682002_23 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000001983 153.0
HKD1_k127_4682002_24 OmpA family K03640 - - 0.000000000000000000000000000000000000002115 162.0
HKD1_k127_4682002_25 - - - - 0.000000000000000000000000000000000000002735 162.0
HKD1_k127_4682002_26 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000000006505 131.0
HKD1_k127_4682002_27 ketosteroid isomerase - - - 0.00000000000000000000000000000242 132.0
HKD1_k127_4682002_28 - - - - 0.00000000000000000000000000483 119.0
HKD1_k127_4682002_29 Forkhead associated domain - - - 0.00000000000000000000003694 108.0
HKD1_k127_4682002_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 598.0
HKD1_k127_4682002_30 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000002971 103.0
HKD1_k127_4682002_31 PFAM AhpC TSA family - - - 0.0000000000000003822 89.0
HKD1_k127_4682002_33 - - - - 0.0001627 53.0
HKD1_k127_4682002_34 - - - - 0.0001966 51.0
HKD1_k127_4682002_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 605.0
HKD1_k127_4682002_5 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 595.0
HKD1_k127_4682002_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 507.0
HKD1_k127_4682002_7 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 485.0
HKD1_k127_4682002_8 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 462.0
HKD1_k127_4682002_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 435.0
HKD1_k127_4706801_0 PFAM Repeat of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 391.0
HKD1_k127_4706801_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004085 255.0
HKD1_k127_4706801_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000002228 172.0
HKD1_k127_4735965_0 helix_turn_helix isocitrate lyase regulation K13641,K19333 - - 0.000000000000000000000001589 105.0
HKD1_k127_4735965_1 Parallel beta-helix repeats - - - 0.000000000000000006279 95.0
HKD1_k127_4767424_0 Carboxypeptidase regulatory-like domain - - - 2.699e-202 674.0
HKD1_k127_4767424_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 589.0
HKD1_k127_4809977_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 408.0
HKD1_k127_4809977_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 399.0
HKD1_k127_4809977_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003094 294.0
HKD1_k127_4809977_3 Histidine kinase - - - 0.000000000000000000000000000000000003257 156.0
HKD1_k127_4809977_4 glyoxalase III activity - - - 0.00000000000000000000000000000003343 132.0
HKD1_k127_4809977_5 PFAM amidohydrolase - - - 0.0000007245 51.0
HKD1_k127_4844820_0 Protein kinase domain K12132 - 2.7.11.1 8.141e-194 630.0
HKD1_k127_4844820_2 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000006061 88.0
HKD1_k127_5030949_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.021e-264 820.0
HKD1_k127_5030949_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.039e-262 824.0
HKD1_k127_5030949_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 497.0
HKD1_k127_5030949_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 460.0
HKD1_k127_5030949_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 449.0
HKD1_k127_5030949_5 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 416.0
HKD1_k127_5030949_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 329.0
HKD1_k127_5030949_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005365 272.0
HKD1_k127_5030949_8 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 247.0
HKD1_k127_5030949_9 23S rRNA-intervening sequence protein - - - 0.000000000000000000162 93.0
HKD1_k127_5034887_0 transmembrane transporter activity K03296 - - 0.0 1445.0
HKD1_k127_5034887_1 MMPL family K03296 - - 0.0 1124.0
HKD1_k127_5034887_2 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 379.0
HKD1_k127_5034887_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
HKD1_k127_5034887_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008274 244.0
HKD1_k127_5034887_5 MMPL family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000002777 215.0
HKD1_k127_5034887_6 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000002915 162.0
HKD1_k127_5034887_7 - - - - 0.000000000007303 68.0
HKD1_k127_5039519_0 serine-type peptidase activity - - - 1.051e-240 768.0
HKD1_k127_5039519_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 394.0
HKD1_k127_5039519_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
HKD1_k127_5039519_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000008941 184.0
HKD1_k127_5047381_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 420.0
HKD1_k127_5047381_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 351.0
HKD1_k127_5047381_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 361.0
HKD1_k127_5050182_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0 1197.0
HKD1_k127_5050182_1 secondary active sulfate transmembrane transporter activity - - - 1.108e-283 896.0
HKD1_k127_5050182_10 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 587.0
HKD1_k127_5050182_11 NAD(P) transhydrogenase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 535.0
HKD1_k127_5050182_12 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 527.0
HKD1_k127_5050182_13 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 493.0
HKD1_k127_5050182_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 494.0
HKD1_k127_5050182_15 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 447.0
HKD1_k127_5050182_16 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 411.0
HKD1_k127_5050182_17 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 374.0
HKD1_k127_5050182_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 308.0
HKD1_k127_5050182_19 proteinase inhibitor I4 serpin K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
HKD1_k127_5050182_2 Glycogen debranching enzyme - - - 1.654e-272 857.0
HKD1_k127_5050182_20 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001331 303.0
HKD1_k127_5050182_21 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006126 284.0
HKD1_k127_5050182_22 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 278.0
HKD1_k127_5050182_23 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HKD1_k127_5050182_24 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000005803 216.0
HKD1_k127_5050182_25 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000001026 209.0
HKD1_k127_5050182_26 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000001595 202.0
HKD1_k127_5050182_28 - - - - 0.0000000000000000000000000000000000000000103 169.0
HKD1_k127_5050182_29 - - - - 0.0000000000000000000000000000000000000843 151.0
HKD1_k127_5050182_3 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.829e-242 765.0
HKD1_k127_5050182_30 Penicillinase repressor - - - 0.000000000000000000000000000000000005617 141.0
HKD1_k127_5050182_31 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000188 143.0
HKD1_k127_5050182_32 - - - - 0.00000000000000000000000000000000751 147.0
HKD1_k127_5050182_33 - - - - 0.00000000000000000000000000003646 128.0
HKD1_k127_5050182_34 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000769 126.0
HKD1_k127_5050182_35 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000003731 124.0
HKD1_k127_5050182_36 SusD family K21572 - - 0.00000000000000000000000004764 119.0
HKD1_k127_5050182_37 - - - - 0.0000000000000000000003183 105.0
HKD1_k127_5050182_38 - - - - 0.000000000000000000001096 108.0
HKD1_k127_5050182_4 TonB dependent receptor - - - 2.574e-236 766.0
HKD1_k127_5050182_5 Putative modulator of DNA gyrase K03568 - - 3.681e-233 733.0
HKD1_k127_5050182_6 MacB-like periplasmic core domain - - - 3.987e-213 689.0
HKD1_k127_5050182_7 Rieske-like [2Fe-2S] domain - - - 2.32e-203 645.0
HKD1_k127_5050182_8 Putative modulator of DNA gyrase - - - 7.391e-194 619.0
HKD1_k127_5050182_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 584.0
HKD1_k127_5065247_0 Glycogen debranching enzyme - - - 0.0 1286.0
HKD1_k127_5065247_1 carbohydrate binding K21298 - 2.4.1.333 0.0 1210.0
HKD1_k127_5065247_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 557.0
HKD1_k127_5065247_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 321.0
HKD1_k127_5065247_4 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 303.0
HKD1_k127_5065247_5 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000002621 214.0
HKD1_k127_5065247_6 - - - - 0.00000000000000000000000000000000000000000000000000000008724 203.0
HKD1_k127_5065247_7 - - - - 0.000000000000000000000000000000000000000000008065 172.0
HKD1_k127_5073879_0 Aminotransferase class I and II K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 485.0
HKD1_k127_5073879_1 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 441.0
HKD1_k127_5073879_10 belongs to the sigma-70 factor family - - - 0.000475 51.0
HKD1_k127_5073879_2 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003149 284.0
HKD1_k127_5073879_3 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000005897 217.0
HKD1_k127_5073879_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000000006413 181.0
HKD1_k127_5073879_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000003581 175.0
HKD1_k127_5073879_6 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000001952 146.0
HKD1_k127_5073879_7 - - - - 0.0000000002545 68.0
HKD1_k127_5073879_8 - - - - 0.00000001183 63.0
HKD1_k127_5073879_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000005806 58.0
HKD1_k127_5082940_0 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000002817 242.0
HKD1_k127_5100850_0 Tricorn protease homolog K08676 - - 0.0 1452.0
HKD1_k127_5100850_1 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1095.0
HKD1_k127_5100850_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.775e-204 649.0
HKD1_k127_5100850_11 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 1.854e-199 642.0
HKD1_k127_5100850_12 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 597.0
HKD1_k127_5100850_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 599.0
HKD1_k127_5100850_14 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 586.0
HKD1_k127_5100850_15 Nucleoside H+ symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 559.0
HKD1_k127_5100850_16 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 571.0
HKD1_k127_5100850_17 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 522.0
HKD1_k127_5100850_18 PFAM peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 471.0
HKD1_k127_5100850_19 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
HKD1_k127_5100850_2 Involved in the tonB-independent uptake of proteins K03641 - - 9.793e-312 985.0
HKD1_k127_5100850_20 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 433.0
HKD1_k127_5100850_21 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 397.0
HKD1_k127_5100850_22 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
HKD1_k127_5100850_23 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 322.0
HKD1_k127_5100850_24 PFAM Class II aldolase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 311.0
HKD1_k127_5100850_25 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009601 290.0
HKD1_k127_5100850_26 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001007 263.0
HKD1_k127_5100850_27 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000000000000000001858 261.0
HKD1_k127_5100850_28 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000001611 224.0
HKD1_k127_5100850_29 Bacteriocin-protection protein - - - 0.000000000000000000000000000000000000000000000000000000002901 208.0
HKD1_k127_5100850_3 GMC oxidoreductase - - - 4.231e-308 950.0
HKD1_k127_5100850_30 - - - - 0.00000000000000000000000000000000000000000000000000001168 198.0
HKD1_k127_5100850_31 gluconokinase activity K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000001591 194.0
HKD1_k127_5100850_32 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000004861 198.0
HKD1_k127_5100850_33 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000007533 145.0
HKD1_k127_5100850_34 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000001329 152.0
HKD1_k127_5100850_35 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.000000000000000000000000000000000004245 139.0
HKD1_k127_5100850_36 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001237 158.0
HKD1_k127_5100850_37 COG1247 Sortase and related acyltransferases K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.0000000000000000000000000000000004451 137.0
HKD1_k127_5100850_39 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000405 123.0
HKD1_k127_5100850_4 Insulinase (Peptidase family M16) K07263 - - 1.824e-287 913.0
HKD1_k127_5100850_40 Transglycosylase associated protein - - - 0.000000000000000000000000007666 113.0
HKD1_k127_5100850_42 Acetyltransferase (GNAT) domain - - - 0.000000000000000000004533 100.0
HKD1_k127_5100850_44 arabinan catabolic process K17624 - 3.2.1.97 0.000005312 50.0
HKD1_k127_5100850_45 Domain of Unknown Function (DUF350) - - - 0.0001162 50.0
HKD1_k127_5100850_5 glucan 1,4-alpha-glucosidase activity - - - 2.157e-287 892.0
HKD1_k127_5100850_6 Dienelactone hydrolase family - - - 4.416e-284 894.0
HKD1_k127_5100850_7 aminopeptidase N - - - 1.326e-281 880.0
HKD1_k127_5100850_8 PFAM Carbohydrate kinase K00853 - 2.7.1.16 2.207e-244 766.0
HKD1_k127_5100850_9 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.557e-204 653.0
HKD1_k127_5103237_0 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 362.0
HKD1_k127_5103237_1 Domain of unknown function (DUF4062) - - - 0.000000000000000000000000000000000000000000000001632 181.0
HKD1_k127_5103237_2 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000001414 169.0
HKD1_k127_5103237_3 YCII-related domain - - - 0.0000000000000003587 82.0
HKD1_k127_5127587_0 Amino acid permease K03294 - - 0.000000000000000003523 87.0
HKD1_k127_5127587_1 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.00000006866 66.0
HKD1_k127_5129078_0 carbohydrate transmembrane transporter activity K05340,K06216 GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 387.0
HKD1_k127_5129078_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000001461 243.0
HKD1_k127_5129078_2 - - - - 0.00000000000000000000000197 106.0
HKD1_k127_5129078_3 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000001485 111.0
HKD1_k127_5143408_0 secondary active sulfate transmembrane transporter activity - - - 8.91e-312 973.0
HKD1_k127_5143408_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 595.0
HKD1_k127_5143408_2 FlgD Ig-like domain K21449 - - 0.00000000008949 70.0
HKD1_k127_5160513_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1109.0
HKD1_k127_5160513_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.848e-235 771.0
HKD1_k127_5160513_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 339.0
HKD1_k127_5185664_0 siderophore transport K02014 - - 0.0 1113.0
HKD1_k127_5185664_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 508.0
HKD1_k127_5185664_2 homoserine kinase K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000001431 217.0
HKD1_k127_5186776_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1043.0
HKD1_k127_5186776_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 428.0
HKD1_k127_5186776_2 PFAM 2Fe-2S -binding - - - 0.00000000000000000000000000000000000000003985 153.0
HKD1_k127_5186776_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000001953 133.0
HKD1_k127_5186776_4 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000002289 123.0
HKD1_k127_5195740_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1329.0
HKD1_k127_5195740_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.284e-320 992.0
HKD1_k127_5195740_10 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 9.189e-220 726.0
HKD1_k127_5195740_11 Aromatic amino acid lyase K01745 - 4.3.1.3 7.334e-215 679.0
HKD1_k127_5195740_12 DHH family K07462 - - 5.31e-200 638.0
HKD1_k127_5195740_13 SurA N-terminal domain K03770 - 5.2.1.8 9.948e-194 622.0
HKD1_k127_5195740_14 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 604.0
HKD1_k127_5195740_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 573.0
HKD1_k127_5195740_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 563.0
HKD1_k127_5195740_17 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 564.0
HKD1_k127_5195740_18 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 555.0
HKD1_k127_5195740_19 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 535.0
HKD1_k127_5195740_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.052e-289 912.0
HKD1_k127_5195740_20 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 538.0
HKD1_k127_5195740_21 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 535.0
HKD1_k127_5195740_22 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 536.0
HKD1_k127_5195740_23 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 496.0
HKD1_k127_5195740_24 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 487.0
HKD1_k127_5195740_25 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 482.0
HKD1_k127_5195740_26 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 462.0
HKD1_k127_5195740_27 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
HKD1_k127_5195740_28 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 442.0
HKD1_k127_5195740_29 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 442.0
HKD1_k127_5195740_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.807e-288 892.0
HKD1_k127_5195740_30 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 454.0
HKD1_k127_5195740_31 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 446.0
HKD1_k127_5195740_32 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 443.0
HKD1_k127_5195740_33 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 411.0
HKD1_k127_5195740_34 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 402.0
HKD1_k127_5195740_35 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 398.0
HKD1_k127_5195740_36 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 392.0
HKD1_k127_5195740_37 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 379.0
HKD1_k127_5195740_38 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 384.0
HKD1_k127_5195740_39 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 361.0
HKD1_k127_5195740_4 Ftsk_gamma K03466 - - 1.353e-273 863.0
HKD1_k127_5195740_40 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 370.0
HKD1_k127_5195740_41 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 342.0
HKD1_k127_5195740_42 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HKD1_k127_5195740_43 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 325.0
HKD1_k127_5195740_44 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 352.0
HKD1_k127_5195740_45 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 318.0
HKD1_k127_5195740_46 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
HKD1_k127_5195740_47 Met-10+ like-protein K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001834 289.0
HKD1_k127_5195740_48 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004333 266.0
HKD1_k127_5195740_49 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
HKD1_k127_5195740_5 B3/4 domain K01890 - 6.1.1.20 1.808e-262 833.0
HKD1_k127_5195740_50 Arginine K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 265.0
HKD1_k127_5195740_51 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000003445 265.0
HKD1_k127_5195740_52 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
HKD1_k127_5195740_53 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 247.0
HKD1_k127_5195740_54 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000001113 247.0
HKD1_k127_5195740_55 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
HKD1_k127_5195740_56 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004761 232.0
HKD1_k127_5195740_57 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
HKD1_k127_5195740_58 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
HKD1_k127_5195740_59 transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000002961 231.0
HKD1_k127_5195740_6 Endoribonuclease that initiates mRNA decay K18682 - - 5.708e-259 808.0
HKD1_k127_5195740_60 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000006881 217.0
HKD1_k127_5195740_61 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000006341 207.0
HKD1_k127_5195740_62 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000002118 221.0
HKD1_k127_5195740_63 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000009163 196.0
HKD1_k127_5195740_64 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000002938 196.0
HKD1_k127_5195740_65 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000646 185.0
HKD1_k127_5195740_66 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000007798 177.0
HKD1_k127_5195740_67 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000000000000000002787 175.0
HKD1_k127_5195740_68 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000956 167.0
HKD1_k127_5195740_69 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000000000003415 163.0
HKD1_k127_5195740_7 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.561e-253 786.0
HKD1_k127_5195740_70 HIT domain K02503 - - 0.00000000000000000000000000000000000000004398 161.0
HKD1_k127_5195740_71 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000004225 163.0
HKD1_k127_5195740_72 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000001523 151.0
HKD1_k127_5195740_73 - - - - 0.000000000000000000000000000000001198 151.0
HKD1_k127_5195740_74 Domain of unknown function (DUF4321) - - - 0.00000000000000000000000000000001144 129.0
HKD1_k127_5195740_75 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000000000000000815 132.0
HKD1_k127_5195740_76 Outer membrane lipoprotein - - - 0.0000000000000000000000000001944 121.0
HKD1_k127_5195740_77 Ribosomal protein S21 K02970 - - 0.0000000000000000000000000014 116.0
HKD1_k127_5195740_79 Ribosomal protein L35 K02916 - - 0.0000000000000000009276 95.0
HKD1_k127_5195740_8 glucan 1,4-alpha-glucosidase activity - - - 1.185e-250 785.0
HKD1_k127_5195740_80 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000135 91.0
HKD1_k127_5195740_81 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000005435 86.0
HKD1_k127_5195740_82 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000016 74.0
HKD1_k127_5195740_83 - - - - 0.000000002282 66.0
HKD1_k127_5195740_84 cellulase activity K06882 - - 0.00000001805 66.0
HKD1_k127_5195740_9 May be involved in recombinational repair of damaged DNA K03631 - - 9.02e-240 754.0
HKD1_k127_520927_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
HKD1_k127_520927_1 - - - - 0.000000000000000000000000000000005084 134.0
HKD1_k127_520927_2 amino acid activation for nonribosomal peptide biosynthetic process K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000006521 115.0
HKD1_k127_520927_3 ABC-2 family transporter protein - - - 0.00000000000000000000001778 110.0
HKD1_k127_5223771_0 MMPL family K03296 - - 2.471e-245 786.0
HKD1_k127_5223771_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 544.0
HKD1_k127_5223771_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003585 258.0
HKD1_k127_5237234_0 Protein kinase domain K12132 - 2.7.11.1 6.311e-248 803.0
HKD1_k127_5237234_1 Protein export membrane protein - - - 0.00000000000000000000000000000000000000000002992 164.0
HKD1_k127_5237234_2 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001102 104.0
HKD1_k127_5237234_3 Aldo/keto reductase family - - - 0.0000006492 53.0
HKD1_k127_5240201_0 AcrB/AcrD/AcrF family K03296 - - 1.134e-268 839.0
HKD1_k127_5240201_1 ABC transporter K06020 - 3.6.3.25 1.948e-257 805.0
HKD1_k127_5240201_10 - - - - 0.0000000000000000000000000000000000000000002138 169.0
HKD1_k127_5240201_11 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000007974 129.0
HKD1_k127_5240201_12 Erythromycin esterase K06880 - - 0.0000000000000000000005265 110.0
HKD1_k127_5240201_13 - - - - 0.0000000000005679 79.0
HKD1_k127_5240201_14 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.000000000001133 69.0
HKD1_k127_5240201_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 581.0
HKD1_k127_5240201_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 509.0
HKD1_k127_5240201_4 phosphorelay signal transduction system K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 464.0
HKD1_k127_5240201_5 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 349.0
HKD1_k127_5240201_6 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
HKD1_k127_5240201_7 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
HKD1_k127_5240201_8 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000003044 220.0
HKD1_k127_5240201_9 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000001971 203.0
HKD1_k127_5242439_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 553.0
HKD1_k127_5242439_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 519.0
HKD1_k127_5242439_2 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 347.0
HKD1_k127_5242439_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 322.0
HKD1_k127_5242439_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001576 247.0
HKD1_k127_5242439_5 glyoxalase III activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000003311 196.0
HKD1_k127_5242439_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001243 96.0
HKD1_k127_5242439_7 Serine threonine protein kinase - - - 0.0000000239 67.0
HKD1_k127_5243127_0 chitin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
HKD1_k127_5243127_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000001053 122.0
HKD1_k127_5248133_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1179.0
HKD1_k127_5248133_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 7.167e-317 980.0
HKD1_k127_5248133_10 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 351.0
HKD1_k127_5248133_11 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
HKD1_k127_5248133_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 336.0
HKD1_k127_5248133_13 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000002567 265.0
HKD1_k127_5248133_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000001022 211.0
HKD1_k127_5248133_15 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000000001153 201.0
HKD1_k127_5248133_16 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000001611 176.0
HKD1_k127_5248133_17 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000000000004278 157.0
HKD1_k127_5248133_18 - - - - 0.000000000000000000000000000000000005447 142.0
HKD1_k127_5248133_19 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000003822 128.0
HKD1_k127_5248133_2 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 1.289e-293 916.0
HKD1_k127_5248133_22 response regulator, receiver - - - 0.00000003026 59.0
HKD1_k127_5248133_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 9.375e-261 818.0
HKD1_k127_5248133_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 4.389e-203 647.0
HKD1_k127_5248133_5 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 553.0
HKD1_k127_5248133_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 434.0
HKD1_k127_5248133_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 379.0
HKD1_k127_5248133_8 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 368.0
HKD1_k127_5248133_9 Serine dehydratase beta chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 364.0
HKD1_k127_5286748_0 Sortilin, neurotensin receptor 3, - - - 0.0 1336.0
HKD1_k127_5286748_1 TonB dependent receptor K02014 - - 1.986e-201 649.0
HKD1_k127_5286748_10 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 508.0
HKD1_k127_5286748_11 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 458.0
HKD1_k127_5286748_12 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 441.0
HKD1_k127_5286748_13 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 344.0
HKD1_k127_5286748_14 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 338.0
HKD1_k127_5286748_15 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 340.0
HKD1_k127_5286748_16 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
HKD1_k127_5286748_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 316.0
HKD1_k127_5286748_18 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 300.0
HKD1_k127_5286748_19 ErfK ybiS ycfS ynhG family protein K19234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
HKD1_k127_5286748_2 Amidase K01426 - 3.5.1.4 4.816e-200 640.0
HKD1_k127_5286748_20 phosphorelay signal transduction system K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000006589 244.0
HKD1_k127_5286748_21 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000000000000000000000000000000000000000003927 219.0
HKD1_k127_5286748_22 Nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000000000000000007551 216.0
HKD1_k127_5286748_23 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HKD1_k127_5286748_24 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000001577 218.0
HKD1_k127_5286748_25 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000004582 212.0
HKD1_k127_5286748_26 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000003189 190.0
HKD1_k127_5286748_27 - K09700 - - 0.00000000000000000000000000000000000000000003931 164.0
HKD1_k127_5286748_28 Histidine kinase - - - 0.000000000000000000000000000000000000000394 167.0
HKD1_k127_5286748_29 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.0000000000000000000000000000009415 136.0
HKD1_k127_5286748_3 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 593.0
HKD1_k127_5286748_30 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000003554 126.0
HKD1_k127_5286748_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001225 122.0
HKD1_k127_5286748_32 Protein of unknown function (DUF1634) - - - 0.00000000000000000000000001507 115.0
HKD1_k127_5286748_33 - - - - 0.0000000000000000000004243 101.0
HKD1_k127_5286748_34 Protein of unknown function (DUF1569) - - - 0.0000000000000000003899 101.0
HKD1_k127_5286748_36 - - - - 0.00000000000001093 84.0
HKD1_k127_5286748_37 COG1538 Outer membrane protein - - - 0.0000000003382 61.0
HKD1_k127_5286748_38 phosphate-selective porin O and P - - - 0.0000000003713 72.0
HKD1_k127_5286748_39 Chorismate mutase type II K04516 - 5.4.99.5 0.00000002131 61.0
HKD1_k127_5286748_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 591.0
HKD1_k127_5286748_40 Copper binding proteins, plastocyanin/azurin family - - - 0.00000003742 61.0
HKD1_k127_5286748_41 AAA domain - - - 0.0000007392 59.0
HKD1_k127_5286748_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 549.0
HKD1_k127_5286748_6 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 530.0
HKD1_k127_5286748_7 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 520.0
HKD1_k127_5286748_8 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 516.0
HKD1_k127_5286748_9 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 524.0
HKD1_k127_5300798_0 Dehydrogenase K00117 - 1.1.5.2 1.57e-227 726.0
HKD1_k127_5300798_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
HKD1_k127_5300798_10 metalloendopeptidase activity K08602 - - 0.0000000003412 61.0
HKD1_k127_5300798_2 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 459.0
HKD1_k127_5300798_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
HKD1_k127_5300798_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002791 265.0
HKD1_k127_5300798_5 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
HKD1_k127_5300798_6 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000006353 224.0
HKD1_k127_5300798_7 - - - - 0.00000000000000000002663 98.0
HKD1_k127_5300798_8 - - - - 0.0000000000000000005554 94.0
HKD1_k127_5300798_9 - - - - 0.0000000000000308 79.0
HKD1_k127_5303985_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1728.0
HKD1_k127_5303985_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1280.0
HKD1_k127_5303985_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 594.0
HKD1_k127_5303985_11 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 604.0
HKD1_k127_5303985_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 559.0
HKD1_k127_5303985_13 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 528.0
HKD1_k127_5303985_14 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 507.0
HKD1_k127_5303985_15 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 476.0
HKD1_k127_5303985_16 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 465.0
HKD1_k127_5303985_17 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 451.0
HKD1_k127_5303985_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 421.0
HKD1_k127_5303985_19 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 411.0
HKD1_k127_5303985_2 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0 1196.0
HKD1_k127_5303985_20 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 433.0
HKD1_k127_5303985_21 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 398.0
HKD1_k127_5303985_22 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 409.0
HKD1_k127_5303985_23 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 351.0
HKD1_k127_5303985_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 316.0
HKD1_k127_5303985_25 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 309.0
HKD1_k127_5303985_26 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HKD1_k127_5303985_27 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 298.0
HKD1_k127_5303985_28 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
HKD1_k127_5303985_29 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007237 248.0
HKD1_k127_5303985_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 8.347e-306 950.0
HKD1_k127_5303985_30 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000004598 256.0
HKD1_k127_5303985_31 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004126 244.0
HKD1_k127_5303985_32 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000001975 227.0
HKD1_k127_5303985_33 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000004034 229.0
HKD1_k127_5303985_34 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000007807 205.0
HKD1_k127_5303985_35 - - - - 0.000000000000000000000000000000000000000000000000000002219 196.0
HKD1_k127_5303985_36 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000008264 177.0
HKD1_k127_5303985_37 - - - - 0.000000000000000000000000000000000000000000004017 169.0
HKD1_k127_5303985_38 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000039 160.0
HKD1_k127_5303985_39 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000006683 154.0
HKD1_k127_5303985_4 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.69e-266 852.0
HKD1_k127_5303985_40 - - - - 0.00000000000000000000000000009519 115.0
HKD1_k127_5303985_41 BioY family K03523 - - 0.00000000000000000000000004928 124.0
HKD1_k127_5303985_42 Septum formation initiator K05589 - - 0.000000000000000000001061 98.0
HKD1_k127_5303985_43 - - - - 0.0000000000000000004725 93.0
HKD1_k127_5303985_44 - - - - 0.0000000000009115 79.0
HKD1_k127_5303985_46 - - - - 0.00000004475 55.0
HKD1_k127_5303985_47 AI-2E family transporter - - - 0.000003791 59.0
HKD1_k127_5303985_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 6.811e-237 746.0
HKD1_k127_5303985_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.444e-211 670.0
HKD1_k127_5303985_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.43e-204 643.0
HKD1_k127_5303985_8 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 632.0
HKD1_k127_5303985_9 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 612.0
HKD1_k127_5314840_0 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
HKD1_k127_5314840_1 - - - - 0.00000000000000000000000000000000000000000000000000000002923 205.0
HKD1_k127_5314840_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000014 177.0
HKD1_k127_5314840_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000007912 123.0
HKD1_k127_5314840_4 Protein conserved in bacteria - - - 0.0000000000000000000000000001572 123.0
HKD1_k127_5319271_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 395.0
HKD1_k127_5319271_1 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 331.0
HKD1_k127_5319271_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001436 263.0
HKD1_k127_5319271_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005505 274.0
HKD1_k127_5319271_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000003323 156.0
HKD1_k127_5319271_5 - - - - 0.0000000000000000000000000006088 115.0
HKD1_k127_5319271_6 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000001528 64.0
HKD1_k127_5321520_0 Uncharacterized protein family (UPF0051) K09014 - - 7.829e-270 835.0
HKD1_k127_5321520_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 522.0
HKD1_k127_5321520_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 521.0
HKD1_k127_5321520_3 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 413.0
HKD1_k127_5321520_4 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 346.0
HKD1_k127_5321520_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000003655 249.0
HKD1_k127_5321520_6 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000002578 186.0
HKD1_k127_5321520_7 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000626 160.0
HKD1_k127_5321520_8 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000001125 140.0
HKD1_k127_5349552_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 595.0
HKD1_k127_5349552_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 541.0
HKD1_k127_5349552_11 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000007605 59.0
HKD1_k127_5349552_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 456.0
HKD1_k127_5349552_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 403.0
HKD1_k127_5349552_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 398.0
HKD1_k127_5349552_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 353.0
HKD1_k127_5349552_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 317.0
HKD1_k127_5349552_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000002628 228.0
HKD1_k127_5349552_8 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
HKD1_k127_5349552_9 Preprotein translocase subunit K03210 - - 0.00000000000000000000000001957 116.0
HKD1_k127_5361101_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.164e-235 734.0
HKD1_k127_5361101_1 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 571.0
HKD1_k127_5365110_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.625e-221 693.0
HKD1_k127_5365110_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 535.0
HKD1_k127_5365110_10 - - - - 0.000003689 58.0
HKD1_k127_5365110_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 439.0
HKD1_k127_5365110_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 378.0
HKD1_k127_5365110_4 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004881 276.0
HKD1_k127_5365110_6 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000003875 148.0
HKD1_k127_5365110_7 MgtC SapB transporter K07507 - - 0.000000000000000000000000000000002555 138.0
HKD1_k127_5365110_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000001596 78.0
HKD1_k127_5382771_0 4Fe-4S dicluster domain - - - 1.521e-312 970.0
HKD1_k127_5382771_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.027e-259 814.0
HKD1_k127_5382771_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 409.0
HKD1_k127_5382771_11 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 404.0
HKD1_k127_5382771_12 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 379.0
HKD1_k127_5382771_13 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
HKD1_k127_5382771_14 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
HKD1_k127_5382771_15 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 301.0
HKD1_k127_5382771_16 SprT-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000645 237.0
HKD1_k127_5382771_17 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000005642 197.0
HKD1_k127_5382771_18 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000001172 187.0
HKD1_k127_5382771_19 - - - - 0.000000000000000000000000000000000000000000000002587 184.0
HKD1_k127_5382771_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.044e-240 753.0
HKD1_k127_5382771_20 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000001117 167.0
HKD1_k127_5382771_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000004792 156.0
HKD1_k127_5382771_23 - - - - 0.0000000000000000000000000002428 121.0
HKD1_k127_5382771_3 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.871e-208 662.0
HKD1_k127_5382771_4 C-terminus of AA_permease K03294 - - 6.619e-205 650.0
HKD1_k127_5382771_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 599.0
HKD1_k127_5382771_6 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 524.0
HKD1_k127_5382771_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 488.0
HKD1_k127_5382771_8 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 484.0
HKD1_k127_5382771_9 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
HKD1_k127_5438272_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 564.0
HKD1_k127_5438272_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 567.0
HKD1_k127_5438272_10 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000006117 245.0
HKD1_k127_5438272_11 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000162 216.0
HKD1_k127_5438272_12 - - - - 0.000000000000000000000000000000000000000000000000000000006919 218.0
HKD1_k127_5438272_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000001234 196.0
HKD1_k127_5438272_14 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000001956 162.0
HKD1_k127_5438272_15 - - - - 0.000000000000000000000000000000000000001609 153.0
HKD1_k127_5438272_17 Insulinase (Peptidase family M16) - - - 0.000000000000000000000002015 111.0
HKD1_k127_5438272_19 PrcB C-terminal - - - 0.0000000000002116 79.0
HKD1_k127_5438272_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 543.0
HKD1_k127_5438272_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 418.0
HKD1_k127_5438272_4 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 380.0
HKD1_k127_5438272_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 327.0
HKD1_k127_5438272_6 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006995 289.0
HKD1_k127_5438272_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849,K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000198 284.0
HKD1_k127_5438272_8 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000985 259.0
HKD1_k127_5438272_9 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001135 250.0
HKD1_k127_5441792_0 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 409.0
HKD1_k127_5441792_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 349.0
HKD1_k127_5441792_2 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 301.0
HKD1_k127_5441792_3 PFAM O-methyltransferase, family 3 K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000004431 208.0
HKD1_k127_5441792_5 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000004225 133.0
HKD1_k127_5441792_6 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000006083 125.0
HKD1_k127_5480995_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 1.176e-315 998.0
HKD1_k127_5480995_1 TonB-dependent receptor K02014 - - 1.089e-288 914.0
HKD1_k127_5480995_10 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000001411 150.0
HKD1_k127_5480995_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 7.344e-268 832.0
HKD1_k127_5480995_3 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 582.0
HKD1_k127_5480995_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 449.0
HKD1_k127_5480995_5 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 341.0
HKD1_k127_5480995_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 316.0
HKD1_k127_5480995_7 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000001506 206.0
HKD1_k127_5480995_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000009209 179.0
HKD1_k127_5480995_9 SusD family K21572 - - 0.0000000000000000000000000000000000000005237 159.0
HKD1_k127_5504700_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1086.0
HKD1_k127_5504700_1 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 603.0
HKD1_k127_5504700_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 464.0
HKD1_k127_5504700_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
HKD1_k127_5504700_4 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
HKD1_k127_5504700_5 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000001896 162.0
HKD1_k127_550678_0 lipopolysaccharide transport K22110 - - 0.0 1185.0
HKD1_k127_550678_1 GMC oxidoreductase - - - 6.867e-293 906.0
HKD1_k127_550678_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 599.0
HKD1_k127_550678_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 333.0
HKD1_k127_550678_4 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000003522 272.0
HKD1_k127_550678_5 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000001438 198.0
HKD1_k127_5508560_0 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001317 266.0
HKD1_k127_5508560_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000003444 233.0
HKD1_k127_5515638_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 611.0
HKD1_k127_5515638_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 433.0
HKD1_k127_5515638_10 DoxX - - - 0.00001934 48.0
HKD1_k127_5515638_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 296.0
HKD1_k127_5515638_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
HKD1_k127_5515638_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000008064 162.0
HKD1_k127_5515638_5 ECF sigma factor - - - 0.000000000000000000000000000000000003331 145.0
HKD1_k127_5515638_6 Subtilase family - - - 0.000000000000000000000000000000006656 140.0
HKD1_k127_5515638_7 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000003226 105.0
HKD1_k127_5515638_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000678 70.0
HKD1_k127_5515638_9 Metal-sensitive transcriptional repressor - - - 0.000003978 51.0
HKD1_k127_561667_0 cellulose binding - - - 0.0 1269.0
HKD1_k127_561667_1 Peptidase M14, carboxypeptidase A - - - 0.0 1223.0
HKD1_k127_561667_10 - - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD1_k127_561667_11 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000003121 158.0
HKD1_k127_561667_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000004523 162.0
HKD1_k127_561667_13 GrpB protein - - - 0.000000000000000000000000000000000058 140.0
HKD1_k127_561667_14 - - - - 0.000000000000000000232 91.0
HKD1_k127_561667_15 efflux transmembrane transporter activity - - - 0.00000003742 61.0
HKD1_k127_561667_16 - - - - 0.00001009 55.0
HKD1_k127_561667_17 response regulator - - - 0.00004545 51.0
HKD1_k127_561667_18 chitin binding - - - 0.0004623 46.0
HKD1_k127_561667_2 PA14 domain K05349 - 3.2.1.21 0.0 1050.0
HKD1_k127_561667_3 lysine biosynthetic process via aminoadipic acid - - - 1.045e-269 855.0
HKD1_k127_561667_4 Peptidase family M1 domain - - - 4.302e-255 797.0
HKD1_k127_561667_5 Alpha-L-fucosidase K01206 - 3.2.1.51 2.469e-226 712.0
HKD1_k127_561667_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 453.0
HKD1_k127_561667_7 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 409.0
HKD1_k127_561667_8 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004008 246.0
HKD1_k127_561667_9 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000000003675 228.0
HKD1_k127_5705485_0 alginic acid biosynthetic process - - - 4.478e-234 745.0
HKD1_k127_5705485_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 494.0
HKD1_k127_5705485_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 419.0
HKD1_k127_5705485_3 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000026 213.0
HKD1_k127_5705485_4 Tetratricopeptide repeat - - - 0.0000000000205 78.0
HKD1_k127_5705485_5 KaiC - - - 0.0000008814 61.0
HKD1_k127_5705485_6 Autotransporter beta-domain - - - 0.0000351 54.0
HKD1_k127_5755892_0 Amidohydrolase family - - - 5.737e-249 780.0
HKD1_k127_5755892_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
HKD1_k127_5755892_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 444.0
HKD1_k127_5755892_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 420.0
HKD1_k127_5755892_4 Peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000002761 243.0
HKD1_k127_5755892_5 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000003155 132.0
HKD1_k127_5755892_6 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000004287 107.0
HKD1_k127_5768990_0 alpha-galactosidase - - - 5.603e-238 754.0
HKD1_k127_5768990_1 Sodium:solute symporter family - - - 7.46e-230 739.0
HKD1_k127_5768990_10 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000001051 213.0
HKD1_k127_5768990_11 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000001488 134.0
HKD1_k127_5768990_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000001943 126.0
HKD1_k127_5768990_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001763 115.0
HKD1_k127_5768990_14 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000002033 119.0
HKD1_k127_5768990_15 - - - - 0.000000000000002098 87.0
HKD1_k127_5768990_16 Ribosomal protein S21 K02970 - - 0.000000000000005861 76.0
HKD1_k127_5768990_17 metal cluster binding K06940,K18475 - - 0.00000000002681 72.0
HKD1_k127_5768990_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 3.043e-194 613.0
HKD1_k127_5768990_3 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 591.0
HKD1_k127_5768990_4 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 460.0
HKD1_k127_5768990_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 347.0
HKD1_k127_5768990_6 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 310.0
HKD1_k127_5768990_7 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 311.0
HKD1_k127_5768990_8 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000005504 209.0
HKD1_k127_5768990_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000001486 228.0
HKD1_k127_6038177_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000002443 167.0
HKD1_k127_6038177_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000007466 145.0
HKD1_k127_6038177_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000004949 128.0
HKD1_k127_6038177_3 Acetyltransferase (Isoleucine patch superfamily) - - - 0.000000000000000000007387 94.0
HKD1_k127_6048379_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.197e-234 736.0
HKD1_k127_6048379_1 exoribonuclease II activity K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
HKD1_k127_6048379_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 513.0
HKD1_k127_6048379_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 471.0
HKD1_k127_6048379_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 393.0
HKD1_k127_6048379_5 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000006043 232.0
HKD1_k127_6057007_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1088.0
HKD1_k127_6057007_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 469.0
HKD1_k127_6057007_10 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 269.0
HKD1_k127_6057007_11 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000146 258.0
HKD1_k127_6057007_12 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000734 257.0
HKD1_k127_6057007_13 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HKD1_k127_6057007_14 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001648 172.0
HKD1_k127_6057007_15 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000501 160.0
HKD1_k127_6057007_16 - - - - 0.00000000000000000000000000000000000000001118 158.0
HKD1_k127_6057007_18 Pathogenicity locus - - - 0.00000000000000000000000000000002347 128.0
HKD1_k127_6057007_19 - - - - 0.000000000000000000000000001291 113.0
HKD1_k127_6057007_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 425.0
HKD1_k127_6057007_20 Vitamin K epoxide reductase family - - - 0.0000000000000000000000008829 110.0
HKD1_k127_6057007_23 Domain of unknown function (DUF1707) - - - 0.00000000000002246 81.0
HKD1_k127_6057007_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000003763 69.0
HKD1_k127_6057007_25 Transcriptional regulator PadR family protein - - - 0.00002173 54.0
HKD1_k127_6057007_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 369.0
HKD1_k127_6057007_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 366.0
HKD1_k127_6057007_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 333.0
HKD1_k127_6057007_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 336.0
HKD1_k127_6057007_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
HKD1_k127_6057007_8 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005886 279.0
HKD1_k127_6057007_9 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005615 276.0
HKD1_k127_6063467_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1032.0
HKD1_k127_6063467_1 ABC1 family - - - 1.358e-281 875.0
HKD1_k127_6063467_10 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000002295 162.0
HKD1_k127_6063467_11 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000001347 149.0
HKD1_k127_6063467_12 Prolyl oligopeptidase family - - - 0.00000000000001213 73.0
HKD1_k127_6063467_13 Selenoprotein, putative - - - 0.00000000007331 75.0
HKD1_k127_6063467_2 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 573.0
HKD1_k127_6063467_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 504.0
HKD1_k127_6063467_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 489.0
HKD1_k127_6063467_5 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 464.0
HKD1_k127_6063467_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
HKD1_k127_6063467_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 303.0
HKD1_k127_6063467_8 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 254.0
HKD1_k127_6063467_9 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005063 274.0
HKD1_k127_60921_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1035.0
HKD1_k127_60921_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.361e-215 677.0
HKD1_k127_60921_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 518.0
HKD1_k127_60921_11 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 512.0
HKD1_k127_60921_12 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 504.0
HKD1_k127_60921_13 Bacterial dnaA protein K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 507.0
HKD1_k127_60921_14 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 453.0
HKD1_k127_60921_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 437.0
HKD1_k127_60921_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 430.0
HKD1_k127_60921_17 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 419.0
HKD1_k127_60921_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 398.0
HKD1_k127_60921_19 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 385.0
HKD1_k127_60921_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.403e-198 626.0
HKD1_k127_60921_20 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 384.0
HKD1_k127_60921_21 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 346.0
HKD1_k127_60921_22 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 351.0
HKD1_k127_60921_23 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 322.0
HKD1_k127_60921_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 334.0
HKD1_k127_60921_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 329.0
HKD1_k127_60921_26 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 287.0
HKD1_k127_60921_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005625 291.0
HKD1_k127_60921_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008573 258.0
HKD1_k127_60921_29 - - - - 0.000000000000000000000000000000000000000000000000000001995 216.0
HKD1_k127_60921_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 599.0
HKD1_k127_60921_30 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000113 191.0
HKD1_k127_60921_31 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000001929 187.0
HKD1_k127_60921_32 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000002624 179.0
HKD1_k127_60921_33 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000001506 184.0
HKD1_k127_60921_34 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000768 145.0
HKD1_k127_60921_35 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000001717 149.0
HKD1_k127_60921_36 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000004806 126.0
HKD1_k127_60921_37 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000005411 115.0
HKD1_k127_60921_39 - - - - 0.000000000000007323 76.0
HKD1_k127_60921_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 565.0
HKD1_k127_60921_40 chemotaxis K03408 - - 0.000000000002001 74.0
HKD1_k127_60921_41 - - - - 0.00000000001717 76.0
HKD1_k127_60921_42 Roadblock/LC7 domain - - - 0.00006355 52.0
HKD1_k127_60921_43 Tetratricopeptide repeat - - - 0.00008683 54.0
HKD1_k127_60921_44 Roadblock/LC7 domain K07131 - - 0.0002077 53.0
HKD1_k127_60921_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 559.0
HKD1_k127_60921_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 551.0
HKD1_k127_60921_7 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 552.0
HKD1_k127_60921_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 521.0
HKD1_k127_60921_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 515.0
HKD1_k127_6104525_0 neurotransmitter:sodium symporter activity K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 606.0
HKD1_k127_6104525_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 438.0
HKD1_k127_6104525_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 346.0
HKD1_k127_6107531_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 571.0
HKD1_k127_6107531_1 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 555.0
HKD1_k127_6107531_10 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
HKD1_k127_6107531_11 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 267.0
HKD1_k127_6107531_12 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000005925 270.0
HKD1_k127_6107531_13 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000002857 246.0
HKD1_k127_6107531_14 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000001275 237.0
HKD1_k127_6107531_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000001623 228.0
HKD1_k127_6107531_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000003917 216.0
HKD1_k127_6107531_17 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
HKD1_k127_6107531_18 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K06956 - - 0.000000000000000000000000000000000000000000000000000000000005465 234.0
HKD1_k127_6107531_19 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD1_k127_6107531_2 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 561.0
HKD1_k127_6107531_20 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001289 210.0
HKD1_k127_6107531_21 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000004816 195.0
HKD1_k127_6107531_22 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000001477 186.0
HKD1_k127_6107531_23 - - - - 0.0000000000000000000000000000000000000000000002045 193.0
HKD1_k127_6107531_24 chlorophyll binding K03286,K03640 - - 0.0000000000000000000000000000005631 138.0
HKD1_k127_6107531_25 Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000001452 110.0
HKD1_k127_6107531_26 PFAM Beta-lactamase - - - 0.00000000000000000000008488 103.0
HKD1_k127_6107531_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000004064 72.0
HKD1_k127_6107531_28 Domain of unknown function (DUF4412) - - - 0.00000005019 63.0
HKD1_k127_6107531_29 lipid glycosylation K16444 - 2.4.1.310 0.00008862 53.0
HKD1_k127_6107531_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 564.0
HKD1_k127_6107531_30 - - - - 0.0002146 51.0
HKD1_k127_6107531_31 - - - - 0.0006617 51.0
HKD1_k127_6107531_4 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 492.0
HKD1_k127_6107531_5 ABC-type antimicrobial peptide transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 505.0
HKD1_k127_6107531_6 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 430.0
HKD1_k127_6107531_7 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 370.0
HKD1_k127_6107531_8 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006767 285.0
HKD1_k127_6107531_9 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006972 289.0
HKD1_k127_6125310_0 Sortilin, neurotensin receptor 3, - - - 1.016e-270 845.0
HKD1_k127_6125310_1 PQQ enzyme repeat K00117 - 1.1.5.2 8.117e-261 819.0
HKD1_k127_6125310_10 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 331.0
HKD1_k127_6125310_11 Domain of unknown function (DUF4974) K07165 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007824 261.0
HKD1_k127_6125310_12 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD1_k127_6125310_13 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000000005693 196.0
HKD1_k127_6125310_14 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000001317 195.0
HKD1_k127_6125310_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002488 196.0
HKD1_k127_6125310_16 - - - - 0.00000000000000000000000000000000000000000000000000107 194.0
HKD1_k127_6125310_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000001414 192.0
HKD1_k127_6125310_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000000000000000000000000000000003718 180.0
HKD1_k127_6125310_19 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000001584 161.0
HKD1_k127_6125310_2 GMC oxidoreductase K19813 - 1.1.5.9 2.679e-240 755.0
HKD1_k127_6125310_20 glyoxalase III activity - - - 0.000000000000000000000000000000000000001784 159.0
HKD1_k127_6125310_21 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000001261 144.0
HKD1_k127_6125310_22 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000142 127.0
HKD1_k127_6125310_23 - - - - 0.00000000000000000000000001705 116.0
HKD1_k127_6125310_24 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001463 100.0
HKD1_k127_6125310_25 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000008308 87.0
HKD1_k127_6125310_26 Methyltransferase FkbM domain - - - 0.0000000000003999 71.0
HKD1_k127_6125310_27 - - - - 0.0000002585 61.0
HKD1_k127_6125310_28 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00002796 54.0
HKD1_k127_6125310_3 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.836e-218 688.0
HKD1_k127_6125310_4 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 612.0
HKD1_k127_6125310_5 Rieske (2fe-2S) K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 567.0
HKD1_k127_6125310_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 522.0
HKD1_k127_6125310_7 amino acid K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 404.0
HKD1_k127_6125310_8 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
HKD1_k127_6125310_9 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 342.0
HKD1_k127_6129080_0 His Kinase A (phosphoacceptor) domain - - - 2.36e-309 987.0
HKD1_k127_6129080_1 Nitronate monooxygenase - - - 1.86e-207 654.0
HKD1_k127_6129080_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000007815 178.0
HKD1_k127_6129080_11 - - - - 0.00000000000000000000000000000000000001432 152.0
HKD1_k127_6129080_12 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000002261 144.0
HKD1_k127_6129080_13 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000000000199 146.0
HKD1_k127_6129080_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000001979 133.0
HKD1_k127_6129080_15 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000006561 119.0
HKD1_k127_6129080_16 Transcriptional regulator - - - 0.000000000000000000000000005103 122.0
HKD1_k127_6129080_17 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000001689 118.0
HKD1_k127_6129080_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002641 103.0
HKD1_k127_6129080_19 Universal stress protein - - - 0.0000000000000000002075 99.0
HKD1_k127_6129080_2 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 612.0
HKD1_k127_6129080_20 Iron-sulfur cluster assembly protein - - - 0.000000000000000002998 94.0
HKD1_k127_6129080_21 Cupin 2, conserved barrel domain protein - - - 0.00000000000000008424 86.0
HKD1_k127_6129080_22 Domain of Unknown function (DUF542) K07322 - - 0.0000000001151 65.0
HKD1_k127_6129080_23 SCO1/SenC K07152 - - 0.00000001137 68.0
HKD1_k127_6129080_24 - - - - 0.0000003431 59.0
HKD1_k127_6129080_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 444.0
HKD1_k127_6129080_4 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 420.0
HKD1_k127_6129080_5 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.000000000000000000000000000000000000000000000000000000000000000000000759 253.0
HKD1_k127_6129080_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000009845 235.0
HKD1_k127_6129080_7 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000007535 216.0
HKD1_k127_6129080_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
HKD1_k127_6129080_9 cytochrome c oxidase (Subunit II) - - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
HKD1_k127_6133580_0 WD40-like Beta Propeller Repeat - - - 5.133e-237 765.0
HKD1_k127_6133580_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 337.0
HKD1_k127_6133580_2 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 346.0
HKD1_k127_6133580_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001949 198.0
HKD1_k127_6142967_0 Sortilin, neurotensin receptor 3, - - - 0.0 1465.0
HKD1_k127_6142967_1 polysaccharide deacetylase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 579.0
HKD1_k127_6142967_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 409.0
HKD1_k127_6142967_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000005925 215.0
HKD1_k127_6142967_4 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000004167 66.0
HKD1_k127_6144944_0 peptidyl-tyrosine sulfation - - - 0.0 1436.0
HKD1_k127_6144944_1 MFS/sugar transport protein K16211 - - 2.385e-221 696.0
HKD1_k127_6144944_2 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 2.329e-218 695.0
HKD1_k127_6144944_3 hydrolase activity, hydrolyzing O-glycosyl compounds K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 1.283e-201 644.0
HKD1_k127_6144944_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000001328 192.0
HKD1_k127_6145068_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1387.0
HKD1_k127_6145068_1 Outer membrane protein beta-barrel family - - - 0.0 1165.0
HKD1_k127_6145068_10 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 573.0
HKD1_k127_6145068_11 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 567.0
HKD1_k127_6145068_12 phosphatidate phosphatase activity K09474 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 546.0
HKD1_k127_6145068_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 529.0
HKD1_k127_6145068_14 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 512.0
HKD1_k127_6145068_15 Pfam:SusD K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 495.0
HKD1_k127_6145068_16 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 482.0
HKD1_k127_6145068_17 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 436.0
HKD1_k127_6145068_18 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 451.0
HKD1_k127_6145068_19 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 450.0
HKD1_k127_6145068_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.867e-257 807.0
HKD1_k127_6145068_20 Elongation factor Tu domain 2 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 415.0
HKD1_k127_6145068_21 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 381.0
HKD1_k127_6145068_22 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 378.0
HKD1_k127_6145068_23 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 359.0
HKD1_k127_6145068_24 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
HKD1_k127_6145068_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 323.0
HKD1_k127_6145068_26 S4 RNA-binding domain K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
HKD1_k127_6145068_27 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 291.0
HKD1_k127_6145068_28 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 304.0
HKD1_k127_6145068_29 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 282.0
HKD1_k127_6145068_3 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.684e-256 802.0
HKD1_k127_6145068_30 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
HKD1_k127_6145068_31 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002384 257.0
HKD1_k127_6145068_32 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004951 267.0
HKD1_k127_6145068_33 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002709 257.0
HKD1_k127_6145068_34 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001642 259.0
HKD1_k127_6145068_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005057 246.0
HKD1_k127_6145068_36 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000004205 241.0
HKD1_k127_6145068_37 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
HKD1_k127_6145068_38 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000000000000000000000000000000000000000000000000008045 227.0
HKD1_k127_6145068_39 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000005769 224.0
HKD1_k127_6145068_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.27e-251 788.0
HKD1_k127_6145068_40 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
HKD1_k127_6145068_41 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000005715 191.0
HKD1_k127_6145068_42 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000003095 188.0
HKD1_k127_6145068_43 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000000004634 136.0
HKD1_k127_6145068_44 Segregation and condensation complex subunit ScpB - - - 0.0000000000000000000000000000002515 133.0
HKD1_k127_6145068_45 PTS system fructose IIA component K02744 - - 0.000000000000000000000000000003359 124.0
HKD1_k127_6145068_46 Zinc finger domain - - - 0.000000000000000000000000001898 124.0
HKD1_k127_6145068_47 Regulatory protein, FmdB family - - - 0.0000000000000000000000004645 109.0
HKD1_k127_6145068_48 protein secretion K21449 - - 0.0000000000000000000000007601 109.0
HKD1_k127_6145068_49 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000006057 106.0
HKD1_k127_6145068_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.09e-228 715.0
HKD1_k127_6145068_50 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000002914 90.0
HKD1_k127_6145068_51 Transcriptional regulator PadR-like family - - - 0.0000000000000003322 85.0
HKD1_k127_6145068_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.665e-225 704.0
HKD1_k127_6145068_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.708e-204 643.0
HKD1_k127_6145068_8 Competence protein K02238 - - 1.374e-196 637.0
HKD1_k127_6145068_9 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 607.0
HKD1_k127_6146269_0 Involved in the tonB-independent uptake of proteins - - - 0.0 1200.0
HKD1_k127_6146269_1 HELICc2 K03722 - 3.6.4.12 0.0 1149.0
HKD1_k127_6146269_10 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 589.0
HKD1_k127_6146269_11 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 512.0
HKD1_k127_6146269_12 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 499.0
HKD1_k127_6146269_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 407.0
HKD1_k127_6146269_14 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 399.0
HKD1_k127_6146269_15 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 362.0
HKD1_k127_6146269_16 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
HKD1_k127_6146269_17 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 358.0
HKD1_k127_6146269_18 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 337.0
HKD1_k127_6146269_19 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 332.0
HKD1_k127_6146269_2 Required for chromosome condensation and partitioning K03529 - - 9.298e-257 816.0
HKD1_k127_6146269_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 322.0
HKD1_k127_6146269_21 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 307.0
HKD1_k127_6146269_22 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 286.0
HKD1_k127_6146269_23 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 269.0
HKD1_k127_6146269_24 metallochaperone-like domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
HKD1_k127_6146269_25 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001191 248.0
HKD1_k127_6146269_26 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
HKD1_k127_6146269_27 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000001176 228.0
HKD1_k127_6146269_28 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000002062 226.0
HKD1_k127_6146269_29 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000117 232.0
HKD1_k127_6146269_3 nuclear chromosome segregation - - - 9.343e-247 803.0
HKD1_k127_6146269_30 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000539 243.0
HKD1_k127_6146269_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000006031 231.0
HKD1_k127_6146269_32 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000001638 233.0
HKD1_k127_6146269_33 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000001667 222.0
HKD1_k127_6146269_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000008398 209.0
HKD1_k127_6146269_35 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000001067 205.0
HKD1_k127_6146269_36 - - - - 0.00000000000000000000000000000000000000000000000000005212 198.0
HKD1_k127_6146269_37 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000008793 199.0
HKD1_k127_6146269_38 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD1_k127_6146269_39 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000004291 169.0
HKD1_k127_6146269_4 amine dehydrogenase activity K17285 - - 4.011e-242 754.0
HKD1_k127_6146269_40 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000001854 166.0
HKD1_k127_6146269_41 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000005133 167.0
HKD1_k127_6146269_42 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.0000000000000000000000000000000786 142.0
HKD1_k127_6146269_43 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001852 109.0
HKD1_k127_6146269_44 - - - - 0.0000000000000000000000001217 122.0
HKD1_k127_6146269_45 DUF218 domain - - - 0.00000000000000000000000203 116.0
HKD1_k127_6146269_46 - - - - 0.000000000000000002652 95.0
HKD1_k127_6146269_47 - - - - 0.000000000000000009459 89.0
HKD1_k127_6146269_5 (ABC) transporter K06147,K06148 - - 8.413e-214 680.0
HKD1_k127_6146269_50 - - - - 0.0004795 50.0
HKD1_k127_6146269_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.557e-212 671.0
HKD1_k127_6146269_7 - - - - 4.099e-196 621.0
HKD1_k127_6146269_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 2.788e-194 610.0
HKD1_k127_6146269_9 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 578.0
HKD1_k127_6159862_0 phospholipase C - - - 0.0 1111.0
HKD1_k127_6159862_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.49e-309 958.0
HKD1_k127_6159862_10 YceI-like domain - - - 0.0001702 54.0
HKD1_k127_6159862_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.567e-302 942.0
HKD1_k127_6159862_3 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 6.189e-201 644.0
HKD1_k127_6159862_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 546.0
HKD1_k127_6159862_5 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 464.0
HKD1_k127_6159862_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000007393 221.0
HKD1_k127_6159862_7 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
HKD1_k127_6159862_8 protein conserved in bacteria - - - 0.00000000000000000000000001707 121.0
HKD1_k127_6159862_9 Protein of unknown function (DUF2442) - - - 0.00001802 53.0
HKD1_k127_6168895_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 3.887e-256 819.0
HKD1_k127_6168895_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 513.0
HKD1_k127_6168895_10 2 iron, 2 sulfur cluster binding K00087,K03518,K07302,K13483 - 1.17.1.4,1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000002873 176.0
HKD1_k127_6168895_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000001547 172.0
HKD1_k127_6168895_12 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000313 156.0
HKD1_k127_6168895_13 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000002789 151.0
HKD1_k127_6168895_2 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 464.0
HKD1_k127_6168895_3 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 434.0
HKD1_k127_6168895_4 polyketide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 321.0
HKD1_k127_6168895_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000108 284.0
HKD1_k127_6168895_6 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000006166 252.0
HKD1_k127_6168895_7 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002132 251.0
HKD1_k127_6168895_8 alcohol dehydrogenase K18382 - - 0.0000000000000000000000000000000000000000000000000000000000004777 222.0
HKD1_k127_6168895_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000001347 189.0
HKD1_k127_6169716_0 MacB-like periplasmic core domain - - - 1.502e-247 786.0
HKD1_k127_6169716_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000002424 110.0
HKD1_k127_6169716_2 MarR family - - - 0.00004984 51.0
HKD1_k127_6170850_0 domain, Protein K01212,K12287,K20276 - 3.2.1.65 1.621e-290 945.0
HKD1_k127_6170850_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 519.0
HKD1_k127_6170850_2 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 453.0
HKD1_k127_6170850_3 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 331.0
HKD1_k127_6170850_4 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002197 257.0
HKD1_k127_6170850_5 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000009852 233.0
HKD1_k127_6170850_6 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.0000000000000000000000000000000000000003339 157.0
HKD1_k127_6170850_7 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000000000000001896 134.0
HKD1_k127_6170850_8 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000001142 59.0
HKD1_k127_6170850_9 regulator - - - 0.0001122 52.0
HKD1_k127_6173000_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 378.0
HKD1_k127_6173000_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 333.0
HKD1_k127_6173000_2 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000000000000001494 203.0
HKD1_k127_6173000_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000005797 192.0
HKD1_k127_6173000_4 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000001088 173.0
HKD1_k127_6173000_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000002679 109.0
HKD1_k127_6212083_0 Proprotein convertase P-domain - - - 6.33e-226 720.0
HKD1_k127_6212083_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 515.0
HKD1_k127_6212083_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000004328 228.0
HKD1_k127_6212083_3 AAA ATPase domain - - - 0.0000001142 59.0
HKD1_k127_6212083_4 Putative restriction endonuclease - - - 0.000009598 50.0
HKD1_k127_6212083_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00001512 56.0
HKD1_k127_6228406_0 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 469.0
HKD1_k127_6228406_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002829 277.0
HKD1_k127_6228406_2 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000002184 164.0
HKD1_k127_6228406_3 PFAM GtrA family protein - - - 0.0000000000000000000000000006039 121.0
HKD1_k127_6228406_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000001741 93.0
HKD1_k127_6240499_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1028.0
HKD1_k127_6240499_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 3.781e-233 756.0
HKD1_k127_6240499_10 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000009402 183.0
HKD1_k127_6240499_11 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.000000000000000000000000000000000000000000000001763 185.0
HKD1_k127_6240499_12 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000004665 157.0
HKD1_k127_6240499_13 DinB family - - - 0.0000000000000000000000000000000000001252 149.0
HKD1_k127_6240499_14 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000001124 123.0
HKD1_k127_6240499_15 - - - - 0.0000009853 61.0
HKD1_k127_6240499_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00002441 53.0
HKD1_k127_6240499_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00008138 53.0
HKD1_k127_6240499_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 547.0
HKD1_k127_6240499_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 528.0
HKD1_k127_6240499_4 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 494.0
HKD1_k127_6240499_5 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 461.0
HKD1_k127_6240499_6 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 429.0
HKD1_k127_6240499_7 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000008157 229.0
HKD1_k127_6240499_9 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000005571 201.0
HKD1_k127_6250572_0 Phosphoesterase family - - - 1.536e-201 651.0
HKD1_k127_6250572_1 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 613.0
HKD1_k127_6250572_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000585 106.0
HKD1_k127_6250572_3 Domain of unknown function (DUF4115) - - - 0.00002989 55.0
HKD1_k127_627335_0 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 5.606e-266 835.0
HKD1_k127_627335_1 Amidohydrolase family - - - 6.257e-261 815.0
HKD1_k127_627335_10 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007366 246.0
HKD1_k127_627335_11 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000003482 199.0
HKD1_k127_627335_12 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000001155 156.0
HKD1_k127_627335_13 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000001757 97.0
HKD1_k127_627335_14 MacB-like periplasmic core domain - - - 0.00000000000000000005797 101.0
HKD1_k127_627335_2 Peptidase family M28 - - - 1.668e-239 753.0
HKD1_k127_627335_3 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 2.322e-228 711.0
HKD1_k127_627335_4 Peptidase family M28 - - - 2.039e-195 629.0
HKD1_k127_627335_5 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 606.0
HKD1_k127_627335_6 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 503.0
HKD1_k127_627335_7 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 470.0
HKD1_k127_627335_8 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 474.0
HKD1_k127_627335_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 294.0
HKD1_k127_6277629_0 Sugar (and other) transporter K03446 - - 1.885e-231 727.0
HKD1_k127_6277629_1 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 414.0
HKD1_k127_6277629_10 Putative serine dehydratase domain - - - 0.0000000000000000000003414 106.0
HKD1_k127_6277629_11 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.0000000000000000002326 90.0
HKD1_k127_6277629_12 - - - - 0.00000000001538 75.0
HKD1_k127_6277629_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 417.0
HKD1_k127_6277629_3 Pfam:SusD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 419.0
HKD1_k127_6277629_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 361.0
HKD1_k127_6277629_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 366.0
HKD1_k127_6277629_6 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000004427 198.0
HKD1_k127_6277629_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009753 177.0
HKD1_k127_6277629_8 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000004266 171.0
HKD1_k127_6277629_9 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000002832 119.0
HKD1_k127_6300242_0 cellulose binding - - - 0.0 1433.0
HKD1_k127_6300242_1 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 5.781e-280 886.0
HKD1_k127_6300242_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
HKD1_k127_6300242_11 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000007301 223.0
HKD1_k127_6300242_12 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000155 227.0
HKD1_k127_6300242_13 CYTH - - - 0.00000000000000000000000000000000000000000005355 168.0
HKD1_k127_6300242_14 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000005307 156.0
HKD1_k127_6300242_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000005659 60.0
HKD1_k127_6300242_16 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00002032 55.0
HKD1_k127_6300242_2 TonB dependent receptor - - - 1.971e-246 788.0
HKD1_k127_6300242_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 530.0
HKD1_k127_6300242_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 530.0
HKD1_k127_6300242_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 437.0
HKD1_k127_6300242_6 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 430.0
HKD1_k127_6300242_7 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 398.0
HKD1_k127_6300242_8 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 377.0
HKD1_k127_6312382_0 Carboxypeptidase regulatory-like domain - - - 0.0 1401.0
HKD1_k127_6312382_1 cellulose binding - - - 0.0 1360.0
HKD1_k127_6312382_10 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 567.0
HKD1_k127_6312382_11 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 567.0
HKD1_k127_6312382_12 FMN-dependent dehydrogenase K00101,K00467 - 1.1.2.3,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 554.0
HKD1_k127_6312382_13 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 445.0
HKD1_k127_6312382_14 PFAM Major Facilitator Superfamily K08224 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 437.0
HKD1_k127_6312382_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 444.0
HKD1_k127_6312382_16 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 407.0
HKD1_k127_6312382_17 alginic acid biosynthetic process K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 409.0
HKD1_k127_6312382_18 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 379.0
HKD1_k127_6312382_19 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 361.0
HKD1_k127_6312382_2 Acetyl xylan esterase (AXE1) - - - 0.0 1086.0
HKD1_k127_6312382_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 367.0
HKD1_k127_6312382_21 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
HKD1_k127_6312382_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 345.0
HKD1_k127_6312382_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 321.0
HKD1_k127_6312382_24 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 317.0
HKD1_k127_6312382_25 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 309.0
HKD1_k127_6312382_26 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HKD1_k127_6312382_27 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 298.0
HKD1_k127_6312382_28 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 300.0
HKD1_k127_6312382_29 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 298.0
HKD1_k127_6312382_3 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 1.643e-312 971.0
HKD1_k127_6312382_30 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000214 228.0
HKD1_k127_6312382_31 nitrous oxide K19341 - - 0.00000000000000000000000000000000000000000000000000000000000002599 225.0
HKD1_k127_6312382_32 ABC-type multidrug transport system ATPase component K19340 - - 0.0000000000000000000000000000000000000000000000000000000000001091 231.0
HKD1_k127_6312382_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000009611 220.0
HKD1_k127_6312382_34 - - - - 0.000000000000000000000000000000000000000000000000000000001939 212.0
HKD1_k127_6312382_35 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000002867 206.0
HKD1_k127_6312382_36 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000002084 202.0
HKD1_k127_6312382_37 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000002568 173.0
HKD1_k127_6312382_38 Universal stress protein family - - - 0.00000000000000000000000000000000000000001363 169.0
HKD1_k127_6312382_39 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000001649 161.0
HKD1_k127_6312382_4 Spermine/spermidine synthase domain - - - 1.69e-275 871.0
HKD1_k127_6312382_40 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000003833 153.0
HKD1_k127_6312382_41 Glyoxalase-like domain - - - 0.000000000000000000000000000000000001179 143.0
HKD1_k127_6312382_42 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001392 134.0
HKD1_k127_6312382_43 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0000000000000000000000000000003367 129.0
HKD1_k127_6312382_44 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000003836 128.0
HKD1_k127_6312382_45 Belongs to the UPF0312 family - - - 0.000000000000000000000000002193 119.0
HKD1_k127_6312382_46 NosL K19342 - - 0.0000000000000000007971 98.0
HKD1_k127_6312382_47 nuclear chromosome segregation - - - 0.0000000000000001793 90.0
HKD1_k127_6312382_48 - - - - 0.000000000000009447 85.0
HKD1_k127_6312382_5 Amidase K01426 - 3.5.1.4 9.774e-247 775.0
HKD1_k127_6312382_50 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000001179 81.0
HKD1_k127_6312382_51 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000001279 74.0
HKD1_k127_6312382_52 Polymer-forming cytoskeletal - - - 0.0000000000194 70.0
HKD1_k127_6312382_53 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000002746 76.0
HKD1_k127_6312382_55 PFAM CBS domain K04767 - - 0.00003558 54.0
HKD1_k127_6312382_56 - - - - 0.0008754 49.0
HKD1_k127_6312382_6 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 621.0
HKD1_k127_6312382_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 590.0
HKD1_k127_6312382_8 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 572.0
HKD1_k127_6312382_9 thymidine phosphorylase K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 576.0
HKD1_k127_6389918_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 473.0
HKD1_k127_6389918_1 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 475.0
HKD1_k127_6389918_10 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000000006903 187.0
HKD1_k127_6389918_11 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000002372 182.0
HKD1_k127_6389918_12 YCII-related domain K09780 - - 0.0000000000000000000000000000000001436 136.0
HKD1_k127_6389918_13 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000001544 153.0
HKD1_k127_6389918_14 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000001029 125.0
HKD1_k127_6389918_15 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000001602 88.0
HKD1_k127_6389918_16 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000032 66.0
HKD1_k127_6389918_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 460.0
HKD1_k127_6389918_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 452.0
HKD1_k127_6389918_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 377.0
HKD1_k127_6389918_5 ATPase-coupled sulfate transmembrane transporter activity K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
HKD1_k127_6389918_6 protein homotetramerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001352 267.0
HKD1_k127_6389918_7 tungstate binding K15495 - - 0.0000000000000000000000000000000000000000000000000000000000000000006727 239.0
HKD1_k127_6389918_8 Domain of unknown function (DUF4403) - - - 0.000000000000000000000000000000000000000000000000000000000000000006328 255.0
HKD1_k127_6389918_9 PFAM ABC transporter related K02017,K15497 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000005611 245.0
HKD1_k127_6407163_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1310.0
HKD1_k127_6407163_1 Elongation factor G, domain IV K02355 - - 6.58e-321 999.0
HKD1_k127_6407163_10 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 479.0
HKD1_k127_6407163_11 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 464.0
HKD1_k127_6407163_12 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 434.0
HKD1_k127_6407163_13 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 403.0
HKD1_k127_6407163_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
HKD1_k127_6407163_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 319.0
HKD1_k127_6407163_16 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 312.0
HKD1_k127_6407163_17 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
HKD1_k127_6407163_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 311.0
HKD1_k127_6407163_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001221 268.0
HKD1_k127_6407163_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 4.55e-271 854.0
HKD1_k127_6407163_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001544 275.0
HKD1_k127_6407163_21 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002942 226.0
HKD1_k127_6407163_22 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000027 198.0
HKD1_k127_6407163_23 - - - - 0.000000000000000000000000000000000000000000000000003489 187.0
HKD1_k127_6407163_24 trehalose biosynthetic process K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000004911 192.0
HKD1_k127_6407163_25 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000001415 192.0
HKD1_k127_6407163_26 - - - - 0.00000000000000000000000000000000000000000000942 173.0
HKD1_k127_6407163_27 - - - - 0.000000000000000000000000000000002319 138.0
HKD1_k127_6407163_28 Histone deacetylase - - - 0.00000000000000000000000000001205 127.0
HKD1_k127_6407163_29 - - - - 0.0000000000000000000000000006212 120.0
HKD1_k127_6407163_3 Serine hydrolase (FSH1) - - - 3.542e-257 809.0
HKD1_k127_6407163_30 - - - - 0.000000000000000000000000008502 119.0
HKD1_k127_6407163_31 - - - - 0.00000000000000000000000001561 112.0
HKD1_k127_6407163_32 - - - - 0.0000000000000000006464 92.0
HKD1_k127_6407163_34 - - - - 0.0000000000001582 78.0
HKD1_k127_6407163_35 Acetyltransferase (GNAT) domain - - - 0.000001808 57.0
HKD1_k127_6407163_36 Protein of unknown function DUF72 - - - 0.0001754 45.0
HKD1_k127_6407163_4 Amidohydrolase family K06015 - 3.5.1.81 2.467e-216 686.0
HKD1_k127_6407163_5 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 6.156e-204 646.0
HKD1_k127_6407163_6 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 594.0
HKD1_k127_6407163_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 527.0
HKD1_k127_6407163_8 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 506.0
HKD1_k127_6407163_9 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 502.0
HKD1_k127_6423000_0 Heat shock 70 kDa protein K04043 - - 0.0 1064.0
HKD1_k127_6423000_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.026e-235 730.0
HKD1_k127_6423000_10 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 337.0
HKD1_k127_6423000_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 322.0
HKD1_k127_6423000_12 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 324.0
HKD1_k127_6423000_13 Cytidylate kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 312.0
HKD1_k127_6423000_14 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HKD1_k127_6423000_15 pilus organization K07346 - - 0.0000000000000000000000000000000000000000001924 169.0
HKD1_k127_6423000_16 CYTH - - - 0.0000000000000000000000000000000000000001373 163.0
HKD1_k127_6423000_17 Peptidase family M48 - - - 0.0000000000000003057 80.0
HKD1_k127_6423000_18 - - - - 0.000000000000001252 85.0
HKD1_k127_6423000_19 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000004607 67.0
HKD1_k127_6423000_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.194e-228 726.0
HKD1_k127_6423000_22 - - - - 0.000003332 56.0
HKD1_k127_6423000_23 calcineurin phosphoesterase - - - 0.000009642 59.0
HKD1_k127_6423000_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 614.0
HKD1_k127_6423000_4 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 573.0
HKD1_k127_6423000_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 525.0
HKD1_k127_6423000_6 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 526.0
HKD1_k127_6423000_7 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 465.0
HKD1_k127_6423000_8 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 451.0
HKD1_k127_6423000_9 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 347.0
HKD1_k127_6497682_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0 1537.0
HKD1_k127_6497682_1 ABC transporter transmembrane region - - - 1.147e-243 782.0
HKD1_k127_6497682_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 565.0
HKD1_k127_6497682_11 mannonate dehydratase activity K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 527.0
HKD1_k127_6497682_12 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 510.0
HKD1_k127_6497682_13 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 499.0
HKD1_k127_6497682_14 Glucose inhibited division protein A K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 455.0
HKD1_k127_6497682_15 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 439.0
HKD1_k127_6497682_16 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 413.0
HKD1_k127_6497682_17 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 404.0
HKD1_k127_6497682_18 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 332.0
HKD1_k127_6497682_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 293.0
HKD1_k127_6497682_2 glucuronate isomerase K01812 - 5.3.1.12 8.422e-212 668.0
HKD1_k127_6497682_20 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001472 273.0
HKD1_k127_6497682_21 2-dehydro-3-deoxy-phosphogluconate aldolase activity K00874,K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.45,4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000005324 277.0
HKD1_k127_6497682_22 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001564 265.0
HKD1_k127_6497682_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004723 250.0
HKD1_k127_6497682_24 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 238.0
HKD1_k127_6497682_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 228.0
HKD1_k127_6497682_26 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000001747 238.0
HKD1_k127_6497682_27 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000005162 224.0
HKD1_k127_6497682_28 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000007648 214.0
HKD1_k127_6497682_29 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000005434 205.0
HKD1_k127_6497682_3 Amino acid permease K03294 - - 2.664e-199 631.0
HKD1_k127_6497682_30 Peptidase, M28 family - - - 0.0000000000000000000000000000000000000000000000000000003947 221.0
HKD1_k127_6497682_31 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000009579 194.0
HKD1_k127_6497682_32 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000305 139.0
HKD1_k127_6497682_33 FR47-like protein - - - 0.00000000000000000001157 106.0
HKD1_k127_6497682_34 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000001586 98.0
HKD1_k127_6497682_35 Helix-hairpin-helix motif K02237 - - 0.000000000000000002627 92.0
HKD1_k127_6497682_36 - - - - 0.0002564 48.0
HKD1_k127_6497682_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 605.0
HKD1_k127_6497682_5 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 593.0
HKD1_k127_6497682_6 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 600.0
HKD1_k127_6497682_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
HKD1_k127_6497682_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 577.0
HKD1_k127_6497682_9 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 552.0
HKD1_k127_65299_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.367e-255 798.0
HKD1_k127_65299_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.427e-237 747.0
HKD1_k127_65299_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 354.0
HKD1_k127_65299_11 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 357.0
HKD1_k127_65299_12 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 334.0
HKD1_k127_65299_13 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 314.0
HKD1_k127_65299_14 lipopolysaccharide transmembrane transporter activity K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006418 276.0
HKD1_k127_65299_15 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000002456 276.0
HKD1_k127_65299_16 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005078 248.0
HKD1_k127_65299_17 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000376 228.0
HKD1_k127_65299_18 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000003404 218.0
HKD1_k127_65299_19 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000005491 213.0
HKD1_k127_65299_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 8.176e-219 687.0
HKD1_k127_65299_20 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000008361 222.0
HKD1_k127_65299_21 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000000000002836 195.0
HKD1_k127_65299_22 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000001666 175.0
HKD1_k127_65299_23 - - - - 0.0000000000000000000000000000000000000002474 156.0
HKD1_k127_65299_24 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000003832 156.0
HKD1_k127_65299_26 transcriptional regulator - - - 0.0000000004633 66.0
HKD1_k127_65299_27 Polysaccharide biosynthesis C-terminal domain - - - 0.00002161 46.0
HKD1_k127_65299_3 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 9.548e-210 659.0
HKD1_k127_65299_4 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 525.0
HKD1_k127_65299_5 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 506.0
HKD1_k127_65299_6 endo-1,4-beta-xylanase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 454.0
HKD1_k127_65299_7 GIY-YIG type nucleases (URI domain) K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 434.0
HKD1_k127_65299_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 434.0
HKD1_k127_65299_9 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 386.0
HKD1_k127_6542560_0 amino acid K03758 - - 1.556e-231 726.0
HKD1_k127_6542560_1 Arginine K01478 - 3.5.3.6 0.000000000000000000000000000000005328 129.0
HKD1_k127_6542560_2 Putative threonine/serine exporter - - - 0.000000000000000000003302 103.0
HKD1_k127_65506_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 545.0
HKD1_k127_65506_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000004546 159.0
HKD1_k127_65506_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000001164 132.0
HKD1_k127_65506_3 Rod shape-determining protein (MreD) K03571 - - 0.00000008451 63.0
HKD1_k127_6582722_0 Prolyl oligopeptidase family - - - 0.0 1249.0
HKD1_k127_6582722_1 Dienelactone hydrolase family - - - 1.717e-295 928.0
HKD1_k127_6582722_10 DinB family - - - 0.0000000000000000000000000000000000000000000000000131 186.0
HKD1_k127_6582722_11 - - - - 0.000000000000000000000000000000000000000000000251 173.0
HKD1_k127_6582722_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000002475 160.0
HKD1_k127_6582722_13 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000008661 160.0
HKD1_k127_6582722_14 DinB family - - - 0.0000000000000000000000000000000000004809 146.0
HKD1_k127_6582722_15 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000002404 131.0
HKD1_k127_6582722_16 - - - - 0.0000000000000000000000000007921 124.0
HKD1_k127_6582722_17 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000002842 90.0
HKD1_k127_6582722_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000002869 81.0
HKD1_k127_6582722_19 Rhodanese Homology Domain - - - 0.0000000009116 68.0
HKD1_k127_6582722_2 Major facilitator Superfamily K08178 - - 2.807e-196 620.0
HKD1_k127_6582722_3 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 609.0
HKD1_k127_6582722_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 572.0
HKD1_k127_6582722_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 315.0
HKD1_k127_6582722_6 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001498 275.0
HKD1_k127_6582722_7 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
HKD1_k127_6582722_8 NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
HKD1_k127_6582722_9 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000003768 198.0
HKD1_k127_6587884_0 protein histidine kinase activity K03407,K07678 - 2.7.13.3 1.448e-284 893.0
HKD1_k127_6587884_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 511.0
HKD1_k127_6587884_10 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.000000000000000000000000000000000000001053 151.0
HKD1_k127_6587884_11 - - - - 0.00000000000000000000000000000000000001122 150.0
HKD1_k127_6587884_13 - - - - 0.000000000000000000000000000000008115 134.0
HKD1_k127_6587884_15 Rieske [2Fe-2S] domain - - - 0.0000000005243 66.0
HKD1_k127_6587884_2 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 420.0
HKD1_k127_6587884_3 Deoxynucleoside kinase K15519 - 2.7.1.74,2.7.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 344.0
HKD1_k127_6587884_4 coenzyme binding K07071 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
HKD1_k127_6587884_5 Gas vesicle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HKD1_k127_6587884_6 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008961 233.0
HKD1_k127_6587884_7 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.0000000000000000000000000000000000000000005151 158.0
HKD1_k127_6587884_8 Gas vesicle protein K - - - 0.00000000000000000000000000000000000000002246 154.0
HKD1_k127_6587884_9 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000429 157.0
HKD1_k127_6620543_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 438.0
HKD1_k127_6620543_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000000000000000000000004227 221.0
HKD1_k127_6620543_2 nUDIX hydrolase K03574,K08320 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 0.00000000000000000000000000000007278 130.0
HKD1_k127_6660974_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 509.0
HKD1_k127_6660974_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 381.0
HKD1_k127_6660974_2 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 350.0
HKD1_k127_6660974_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 339.0
HKD1_k127_6660974_4 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004606 281.0
HKD1_k127_6660974_5 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
HKD1_k127_6660974_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
HKD1_k127_6660974_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000003056 263.0
HKD1_k127_6668532_0 PFAM Enoyl-CoA hydratase isomerase - - - 3.35e-213 685.0
HKD1_k127_6668532_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 2.622e-205 655.0
HKD1_k127_6668532_10 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000001655 125.0
HKD1_k127_6668532_11 AraC-like ligand binding domain - - - 0.000000000000000000000000001421 115.0
HKD1_k127_6668532_12 LmbE family - - - 0.000000000000000000000007151 116.0
HKD1_k127_6668532_13 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000002715 77.0
HKD1_k127_6668532_14 Protein of unknown function (DUF2934) - - - 0.0002789 50.0
HKD1_k127_6668532_2 Peptidase dimerisation domain - - - 7.591e-201 640.0
HKD1_k127_6668532_3 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 595.0
HKD1_k127_6668532_4 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
HKD1_k127_6668532_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 434.0
HKD1_k127_6668532_6 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 402.0
HKD1_k127_6668532_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 311.0
HKD1_k127_6668532_8 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000006125 266.0
HKD1_k127_6668532_9 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000081 180.0
HKD1_k127_6705621_0 efflux transmembrane transporter activity - - - 0.0 1394.0
HKD1_k127_6705621_1 Protein export membrane protein - - - 7.707e-316 980.0
HKD1_k127_6705621_10 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000202 119.0
HKD1_k127_6705621_11 ABC transporter K01990 - - 0.000000000000000000000000003075 128.0
HKD1_k127_6705621_12 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000001054 100.0
HKD1_k127_6705621_13 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000005154 92.0
HKD1_k127_6705621_2 esterase - - - 5.353e-273 853.0
HKD1_k127_6705621_3 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 494.0
HKD1_k127_6705621_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 363.0
HKD1_k127_6705621_5 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 356.0
HKD1_k127_6705621_6 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 317.0
HKD1_k127_6705621_7 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000000248 181.0
HKD1_k127_6705621_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000001441 144.0
HKD1_k127_6705621_9 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000001557 124.0
HKD1_k127_6804236_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.11e-290 902.0
HKD1_k127_6804236_1 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 427.0
HKD1_k127_6804236_3 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
HKD1_k127_6804236_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 291.0
HKD1_k127_6804236_5 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000946 212.0
HKD1_k127_684538_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 597.0
HKD1_k127_684538_1 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 533.0
HKD1_k127_684538_2 histidine kinase HAMP region domain protein - - - 0.00000008543 63.0
HKD1_k127_6884480_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 607.0
HKD1_k127_691186_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 1.097e-240 772.0
HKD1_k127_691186_1 Pfam L-fucose isomerase, C-terminal domain - - - 2.336e-224 708.0
HKD1_k127_691186_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 336.0
HKD1_k127_691186_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 308.0
HKD1_k127_691186_4 Histidine kinase K07644,K18351 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 314.0
HKD1_k127_691186_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000001858 201.0
HKD1_k127_691186_6 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000002015 188.0
HKD1_k127_691186_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000009842 143.0
HKD1_k127_691186_8 domain, Protein - - - 0.000000000000000000000000000958 120.0
HKD1_k127_691186_9 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000204 117.0
HKD1_k127_6964163_0 Zinc carboxypeptidase - - - 0.0 1137.0
HKD1_k127_6964163_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 383.0
HKD1_k127_6964163_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003092 282.0
HKD1_k127_6981991_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 610.0
HKD1_k127_6981991_1 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000000005326 184.0
HKD1_k127_6981991_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000243 166.0
HKD1_k127_6981991_3 Beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000005675 144.0
HKD1_k127_6981991_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000001134 130.0
HKD1_k127_6981991_6 Domain of unknown function (DUF378) K09779 - - 0.00000000000003265 76.0
HKD1_k127_6981991_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000002749 66.0
HKD1_k127_6981991_8 Periplasmic Protein - - - 0.0000004234 61.0
HKD1_k127_702881_0 ASPIC UnbV domain protein - - - 3.045e-295 918.0
HKD1_k127_702881_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 367.0
HKD1_k127_702881_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 319.0
HKD1_k127_702881_3 HD domain - - - 0.00000000000000000000000000000000001238 146.0
HKD1_k127_702881_4 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000008833 97.0
HKD1_k127_702881_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000001333 56.0
HKD1_k127_7064788_0 Large extracellular alpha-helical protein K06894 - - 0.0 1180.0
HKD1_k127_7064788_1 metal-dependent hydrolase with the TIM-barrel fold - - - 8.251e-298 921.0
HKD1_k127_7064788_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000006161 160.0
HKD1_k127_7064788_11 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000002972 159.0
HKD1_k127_7064788_12 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000002077 142.0
HKD1_k127_7064788_14 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000002753 61.0
HKD1_k127_7064788_2 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 495.0
HKD1_k127_7064788_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 513.0
HKD1_k127_7064788_4 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 357.0
HKD1_k127_7064788_5 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
HKD1_k127_7064788_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000001912 195.0
HKD1_k127_7064788_7 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000000000000000000000000000000000006697 186.0
HKD1_k127_7064788_8 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000001715 176.0
HKD1_k127_7064788_9 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000002265 166.0
HKD1_k127_7066890_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1176.0
HKD1_k127_7066890_1 TonB dependent receptor - - - 7.171e-234 758.0
HKD1_k127_7066890_2 beta-galactosidase activity K05970 - 3.1.1.53 7.125e-200 637.0
HKD1_k127_7066890_3 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 343.0
HKD1_k127_7066890_4 Aminotransferase K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 336.0
HKD1_k127_7071017_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.65e-321 995.0
HKD1_k127_7071017_1 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 4.631e-290 912.0
HKD1_k127_7071017_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 371.0
HKD1_k127_7071017_11 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 363.0
HKD1_k127_7071017_12 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 348.0
HKD1_k127_7071017_13 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
HKD1_k127_7071017_14 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000335 285.0
HKD1_k127_7071017_15 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002414 263.0
HKD1_k127_7071017_16 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 258.0
HKD1_k127_7071017_17 Matrixin - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD1_k127_7071017_18 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
HKD1_k127_7071017_19 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000009022 183.0
HKD1_k127_7071017_2 TonB-dependent receptor - - - 5.326e-256 826.0
HKD1_k127_7071017_20 - - - - 0.0000000000000000000000000000000000402 143.0
HKD1_k127_7071017_21 Matrixin - - - 0.00000000000000000000000000001317 128.0
HKD1_k127_7071017_22 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000004359 123.0
HKD1_k127_7071017_23 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000003884 108.0
HKD1_k127_7071017_24 - - - - 0.000000000000000002094 92.0
HKD1_k127_7071017_3 repeat protein - - - 7.783e-248 781.0
HKD1_k127_7071017_4 Protein kinase domain K12132 - 2.7.11.1 2.295e-212 699.0
HKD1_k127_7071017_5 Voltage gated chloride channel - - - 6.767e-200 638.0
HKD1_k127_7071017_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 543.0
HKD1_k127_7071017_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 524.0
HKD1_k127_7071017_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 490.0
HKD1_k127_7071017_9 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HKD1_k127_7072533_0 ASPIC and UnbV - - - 0.0 1337.0
HKD1_k127_7072533_1 ASPIC and UnbV - - - 0.0 1204.0
HKD1_k127_7072533_10 epimerase K00491,K21572 - 1.14.14.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 493.0
HKD1_k127_7072533_11 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 442.0
HKD1_k127_7072533_12 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 415.0
HKD1_k127_7072533_13 transport - - - 0.000000000000000000000000000000000005987 141.0
HKD1_k127_7072533_14 - - - - 0.0000000000005641 72.0
HKD1_k127_7072533_2 TonB dependent receptor - - - 0.0 1133.0
HKD1_k127_7072533_3 electron transport chain K00347,K03614 - 1.6.5.8 2.834e-310 960.0
HKD1_k127_7072533_4 N-Acetylmuramoyl-L-alanine amidase K01187 - 3.2.1.20 4.919e-279 874.0
HKD1_k127_7072533_5 - - - - 2.865e-266 848.0
HKD1_k127_7072533_6 geranylgeranyl reductase activity K14257 - 1.14.19.49 3.125e-229 726.0
HKD1_k127_7072533_7 asparagine synthase K01953 - 6.3.5.4 8.26e-228 711.0
HKD1_k127_7072533_8 Trehalase K01194 - 3.2.1.28 5.572e-213 676.0
HKD1_k127_7072533_9 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 592.0
HKD1_k127_7102059_0 Tricorn protease PDZ domain K08676 - - 0.0 1063.0
HKD1_k127_7102059_1 carboxylic ester hydrolase activity K03929 - - 1.028e-269 837.0
HKD1_k127_7102059_11 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.0000002473 61.0
HKD1_k127_7102059_2 FMN-dependent dehydrogenase K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 542.0
HKD1_k127_7102059_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 364.0
HKD1_k127_7102059_4 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 356.0
HKD1_k127_7102059_5 - - - - 0.0000000000000000000000000000000000000000000000002389 195.0
HKD1_k127_7102059_6 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000001034 159.0
HKD1_k127_7102059_8 Transcriptional regulator - - - 0.00000000000000000000003688 107.0
HKD1_k127_7102059_9 Sh3 type 3 domain protein - - - 0.00000000000001576 84.0
HKD1_k127_7102394_0 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 463.0
HKD1_k127_7102394_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 316.0
HKD1_k127_7116694_0 TonB dependent receptor - - - 0.0 1248.0
HKD1_k127_7116694_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 430.0
HKD1_k127_7116694_10 - - - - 0.0002752 52.0
HKD1_k127_7116694_2 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 413.0
HKD1_k127_7116694_3 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000001346 196.0
HKD1_k127_7116694_4 PFAM YCII-related domain - - - 0.000000000000000000000000000000000000000000000007812 175.0
HKD1_k127_7116694_5 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000003053 151.0
HKD1_k127_7116694_6 - - - - 0.000000000000000000001676 102.0
HKD1_k127_7116694_7 - - - - 0.000000000000013 86.0
HKD1_k127_7116694_9 - - - - 0.0000107 54.0
HKD1_k127_71192_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.000000000000000001547 87.0
HKD1_k127_71192_1 beta-lactamase - - - 0.000000000001088 72.0
HKD1_k127_71192_2 Beta-lactamase - - - 0.0005265 51.0
HKD1_k127_7128795_0 RecQ zinc-binding K03654 - 3.6.4.12 2.563e-238 744.0
HKD1_k127_7128795_1 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 526.0
HKD1_k127_7128795_10 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
HKD1_k127_7128795_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000002989 193.0
HKD1_k127_7128795_12 - - - - 0.00000000000000000000000000000000000000000000001975 177.0
HKD1_k127_7128795_13 Cupin domain - - - 0.0000000000000000000000000000000000000000000001604 171.0
HKD1_k127_7128795_14 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000587 166.0
HKD1_k127_7128795_15 redox protein regulator of disulfide bond formation K04063 - - 0.00000000000000000000000000000000001862 140.0
HKD1_k127_7128795_16 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000004025 121.0
HKD1_k127_7128795_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 432.0
HKD1_k127_7128795_3 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 423.0
HKD1_k127_7128795_4 Putative RNA methylase family UPF0020 K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 384.0
HKD1_k127_7128795_5 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 355.0
HKD1_k127_7128795_6 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 351.0
HKD1_k127_7128795_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 325.0
HKD1_k127_7128795_8 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 298.0
HKD1_k127_7128795_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002131 271.0
HKD1_k127_7129166_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 2.854e-210 672.0
HKD1_k127_7129166_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000006896 78.0
HKD1_k127_7163707_0 PQQ-like domain K00117 - 1.1.5.2 0.0 1118.0
HKD1_k127_7163707_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 487.0
HKD1_k127_7163707_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 476.0
HKD1_k127_7163707_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 391.0
HKD1_k127_7163707_4 Cytochrome c - - - 0.000000000000000000000000000000000005946 154.0
HKD1_k127_7163707_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002254 118.0
HKD1_k127_7172427_0 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 383.0
HKD1_k127_7172427_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
HKD1_k127_7172427_2 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000002741 251.0
HKD1_k127_7172427_3 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000003615 209.0
HKD1_k127_7186409_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1120.0
HKD1_k127_7186409_1 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 6.4e-323 1012.0
HKD1_k127_7186409_10 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 362.0
HKD1_k127_7186409_11 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 355.0
HKD1_k127_7186409_12 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
HKD1_k127_7186409_13 Starch-binding associating with outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
HKD1_k127_7186409_14 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000008277 249.0
HKD1_k127_7186409_15 Tfp pilus assembly protein tip-associated adhesin - - - 0.00000000000000000000000000000000000000000000000000000000003467 226.0
HKD1_k127_7186409_16 - - - - 0.000000000000000000000000000000000000000000000000000000003131 217.0
HKD1_k127_7186409_17 Transcriptional regulator, gntR family - - - 0.0000000000000000000000000000000000000000000000000001378 201.0
HKD1_k127_7186409_18 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.00000000000000000000000000000000000000000009673 168.0
HKD1_k127_7186409_19 Response regulator receiver K02477 - - 0.000000000000000000000000000000000000000002347 172.0
HKD1_k127_7186409_2 TonB dependent receptor - - - 2.864e-293 935.0
HKD1_k127_7186409_20 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000005189 136.0
HKD1_k127_7186409_21 TonB dependent receptor - - - 0.00000000000000000000000765 108.0
HKD1_k127_7186409_22 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.000000000000002332 90.0
HKD1_k127_7186409_23 - - - - 0.0000000000001886 79.0
HKD1_k127_7186409_3 peptidase - - - 3.912e-293 924.0
HKD1_k127_7186409_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 9.082e-290 903.0
HKD1_k127_7186409_5 Beta-L-arabinofuranosidase, GH127 K09955 - - 6.198e-236 760.0
HKD1_k127_7186409_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 626.0
HKD1_k127_7186409_7 AMP-binding enzyme K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 613.0
HKD1_k127_7186409_8 RagB SusD domain protein K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 566.0
HKD1_k127_7186409_9 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 542.0
HKD1_k127_7201624_0 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000002542 169.0
HKD1_k127_7201624_1 sequence-specific DNA binding K07729 - - 0.000000000000005557 78.0
HKD1_k127_7203691_0 Domain of unknown function (DUF5118) - - - 0.0 1187.0
HKD1_k127_7203691_1 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 452.0
HKD1_k127_7203691_10 PFAM VanZ family protein - - - 0.0009203 51.0
HKD1_k127_7203691_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 350.0
HKD1_k127_7203691_3 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000002286 249.0
HKD1_k127_7203691_4 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000005142 147.0
HKD1_k127_7203691_5 - - - - 0.00000000000000000000000000000001067 138.0
HKD1_k127_7203691_6 transport - - - 0.00000000000000000000000000113 129.0
HKD1_k127_7203691_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000001447 95.0
HKD1_k127_7203691_8 Alkylmercury lyase - - - 0.000000002355 63.0
HKD1_k127_7203691_9 VanZ like family - - - 0.0003019 53.0
HKD1_k127_7204826_0 Uncharacterised protein family (UPF0182) K09118 - - 5.096e-229 739.0
HKD1_k127_7204826_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000002291 166.0
HKD1_k127_7204826_2 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000001614 127.0
HKD1_k127_7204826_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000001032 72.0
HKD1_k127_7209973_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.626e-206 654.0
HKD1_k127_7209973_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 476.0
HKD1_k127_7209973_2 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 476.0
HKD1_k127_7209973_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 354.0
HKD1_k127_7209973_4 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000004554 74.0
HKD1_k127_7219848_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 567.0
HKD1_k127_7219848_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 515.0
HKD1_k127_7219848_2 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 456.0
HKD1_k127_7219848_3 DNA recombination - GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
HKD1_k127_7219848_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
HKD1_k127_7219848_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000001486 120.0
HKD1_k127_7284865_0 Carbohydrate family 9 binding domain-like - - - 0.0 1363.0
HKD1_k127_7284865_1 Amidase K02433 - 6.3.5.6,6.3.5.7 1.903e-298 931.0
HKD1_k127_7284865_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 524.0
HKD1_k127_7284865_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006206 238.0
HKD1_k127_7284865_4 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000001253 215.0
HKD1_k127_7284865_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000003261 163.0
HKD1_k127_7284865_6 phospholipase C - - - 0.00000000000000000302 85.0
HKD1_k127_7288309_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1543.0
HKD1_k127_7288309_1 Sortilin, neurotensin receptor 3, - - - 0.0 1513.0
HKD1_k127_7288309_10 unfolded protein binding K18481 - - 0.00000000000000000000000000000000000000000000002497 180.0
HKD1_k127_7288309_11 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.00000000000000000000000000000000000000000000009126 185.0
HKD1_k127_7288309_12 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000004217 166.0
HKD1_k127_7288309_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000007425 164.0
HKD1_k127_7288309_14 Transcriptional regulator - - - 0.00000000000000000000000000000001515 131.0
HKD1_k127_7288309_17 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000003033 92.0
HKD1_k127_7288309_18 Domain of unknown function (DUF4142) K08995 - - 0.0001502 52.0
HKD1_k127_7288309_2 AcrB/AcrD/AcrF family K03296 - - 5.821e-195 620.0
HKD1_k127_7288309_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 451.0
HKD1_k127_7288309_4 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 408.0
HKD1_k127_7288309_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 391.0
HKD1_k127_7288309_6 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 387.0
HKD1_k127_7288309_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 350.0
HKD1_k127_7288309_8 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HKD1_k127_7288309_9 MOSC domain - - - 0.000000000000000000000000000000000000000000000007331 184.0
HKD1_k127_7291141_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 2025.0
HKD1_k127_7291141_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1296.0
HKD1_k127_7291141_10 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 440.0
HKD1_k127_7291141_11 response to heat K03695,K03696,K03697,K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 422.0
HKD1_k127_7291141_12 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 404.0
HKD1_k127_7291141_13 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 381.0
HKD1_k127_7291141_14 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 341.0
HKD1_k127_7291141_15 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 337.0
HKD1_k127_7291141_16 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
HKD1_k127_7291141_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 324.0
HKD1_k127_7291141_18 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 294.0
HKD1_k127_7291141_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001925 279.0
HKD1_k127_7291141_2 TonB dependent receptor - - - 0.0 1058.0
HKD1_k127_7291141_20 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
HKD1_k127_7291141_21 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000006369 228.0
HKD1_k127_7291141_22 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000007353 201.0
HKD1_k127_7291141_23 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000008346 207.0
HKD1_k127_7291141_24 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000005125 196.0
HKD1_k127_7291141_25 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000009255 186.0
HKD1_k127_7291141_26 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000002108 179.0
HKD1_k127_7291141_27 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000000000000002552 151.0
HKD1_k127_7291141_28 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000004615 120.0
HKD1_k127_7291141_3 TonB-dependent receptor - - - 5e-324 1023.0
HKD1_k127_7291141_30 Peptidase family M48 - - - 0.0000003022 54.0
HKD1_k127_7291141_31 Carboxypeptidase regulatory-like domain - - - 0.0005025 51.0
HKD1_k127_7291141_4 TonB dependent receptor - - - 1.117e-304 968.0
HKD1_k127_7291141_5 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.143e-228 724.0
HKD1_k127_7291141_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.319e-205 685.0
HKD1_k127_7291141_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 565.0
HKD1_k127_7291141_8 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 465.0
HKD1_k127_7291141_9 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 442.0
HKD1_k127_7349861_0 FtsX-like permease family K02004 - - 1.087e-253 819.0
HKD1_k127_7349861_1 IMP dehydrogenase activity K03281 - - 2.887e-237 751.0
HKD1_k127_7349861_10 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000005523 145.0
HKD1_k127_7349861_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000001979 133.0
HKD1_k127_7349861_12 - - - - 0.00000000000000000003702 98.0
HKD1_k127_7349861_13 S23 ribosomal protein - - - 0.000000000000004739 80.0
HKD1_k127_7349861_14 - - - - 0.0000000007464 67.0
HKD1_k127_7349861_15 Glucose / Sorbosone dehydrogenase - - - 0.000001531 56.0
HKD1_k127_7349861_2 Chlorophyllase enzyme - - - 2.645e-216 697.0
HKD1_k127_7349861_3 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 364.0
HKD1_k127_7349861_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 344.0
HKD1_k127_7349861_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 305.0
HKD1_k127_7349861_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007463 279.0
HKD1_k127_7349861_7 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000805 240.0
HKD1_k127_7349861_8 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000001096 227.0
HKD1_k127_7349861_9 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000002784 199.0
HKD1_k127_7361790_0 Luciferase-like monooxygenase - - - 2.703e-195 616.0
HKD1_k127_7361790_1 MacB-like periplasmic core domain - - - 0.00000000003123 66.0
HKD1_k127_7361790_2 WD40-like Beta Propeller Repeat - - - 0.00000000007727 70.0
HKD1_k127_7402013_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.419e-250 803.0
HKD1_k127_7402013_1 nuclear chromosome segregation - - - 2.192e-221 731.0
HKD1_k127_7402013_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000003757 131.0
HKD1_k127_7402013_11 Transcriptional regulator, ArsR family - - - 0.0000000815 54.0
HKD1_k127_7402013_13 zinc metalloprotease K11749 - - 0.000321 51.0
HKD1_k127_7402013_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 417.0
HKD1_k127_7402013_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 369.0
HKD1_k127_7402013_4 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 344.0
HKD1_k127_7402013_5 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 331.0
HKD1_k127_7402013_6 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
HKD1_k127_7402013_7 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006193 285.0
HKD1_k127_7402013_8 - - - - 0.00000000000000000000000000000000001165 143.0
HKD1_k127_7402013_9 - - - - 0.00000000000000000000000000000000006422 145.0
HKD1_k127_748783_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
HKD1_k127_748783_1 Helix-hairpin-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 295.0
HKD1_k127_748783_2 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
HKD1_k127_748783_3 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000001264 254.0
HKD1_k127_748783_4 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003962 244.0
HKD1_k127_748783_5 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02003,K05685 - - 0.0000000000000000000000000000000002494 145.0
HKD1_k127_748783_6 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000005115 132.0
HKD1_k127_748783_7 ErfK ybiS ycfS ynhG family protein K19234 - - 0.0000000000000000000001426 109.0
HKD1_k127_7525644_0 Fructose-bisphosphate aldolase class-II - - - 5.034e-215 676.0
HKD1_k127_7525644_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.282e-214 681.0
HKD1_k127_7525644_10 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001175 257.0
HKD1_k127_7525644_11 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007144 241.0
HKD1_k127_7525644_12 YjbR - - - 0.000000000000000000000000000000000000001189 154.0
HKD1_k127_7525644_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000002231 137.0
HKD1_k127_7525644_14 YtxH-like protein - - - 0.0000000000000000000000000000004086 127.0
HKD1_k127_7525644_15 - - - - 0.0000000000009652 72.0
HKD1_k127_7525644_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 607.0
HKD1_k127_7525644_3 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 581.0
HKD1_k127_7525644_4 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
HKD1_k127_7525644_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
HKD1_k127_7525644_6 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 301.0
HKD1_k127_7525644_7 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 287.0
HKD1_k127_7525644_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001606 299.0
HKD1_k127_7525644_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006004 267.0
HKD1_k127_7561718_0 - - - - 0.00006562 55.0
HKD1_k127_7562229_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 2.613e-197 625.0
HKD1_k127_7562229_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 557.0
HKD1_k127_7562229_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 493.0
HKD1_k127_7562229_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 480.0
HKD1_k127_7562229_4 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 445.0
HKD1_k127_7562229_5 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
HKD1_k127_7562229_6 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000005282 153.0
HKD1_k127_7579121_0 CarboxypepD_reg-like domain - - - 0.0 1397.0
HKD1_k127_7579121_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 5.674e-315 983.0
HKD1_k127_7579121_10 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 500.0
HKD1_k127_7579121_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
HKD1_k127_7579121_12 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 432.0
HKD1_k127_7579121_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 381.0
HKD1_k127_7579121_14 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 342.0
HKD1_k127_7579121_15 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 325.0
HKD1_k127_7579121_16 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 293.0
HKD1_k127_7579121_17 zinc ion binding K04477,K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 301.0
HKD1_k127_7579121_18 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001208 282.0
HKD1_k127_7579121_19 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001803 279.0
HKD1_k127_7579121_2 Putative modulator of DNA gyrase K03568 - - 4.913e-239 751.0
HKD1_k127_7579121_20 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
HKD1_k127_7579121_21 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000001479 253.0
HKD1_k127_7579121_22 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005382 258.0
HKD1_k127_7579121_23 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000002692 224.0
HKD1_k127_7579121_24 - - - - 0.0000000000000000000000000000000000000002502 159.0
HKD1_k127_7579121_25 - - - - 0.00000000000000000000000000000000147 134.0
HKD1_k127_7579121_29 - - - - 0.00000000000142 75.0
HKD1_k127_7579121_3 Sigma-54 interaction domain - - - 1.203e-215 677.0
HKD1_k127_7579121_4 Beta-eliminating lyase K00639 - 2.3.1.29 2.665e-203 639.0
HKD1_k127_7579121_5 Pfam:SusD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 610.0
HKD1_k127_7579121_6 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 612.0
HKD1_k127_7579121_7 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 577.0
HKD1_k127_7579121_8 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 563.0
HKD1_k127_7579121_9 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 542.0
HKD1_k127_7726163_0 Amidohydrolase family - - - 2.904e-208 662.0
HKD1_k127_7726163_1 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 494.0
HKD1_k127_7726163_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000002514 250.0
HKD1_k127_7726163_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004209 235.0
HKD1_k127_7726163_4 - K09004 - - 0.0000000000000000000000000000009512 137.0
HKD1_k127_7726163_5 Periplasmic or secreted lipoprotein - - - 0.00006495 53.0
HKD1_k127_78255_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 8.551e-219 692.0
HKD1_k127_78255_1 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 542.0
HKD1_k127_78255_10 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000114 145.0
HKD1_k127_78255_11 Sigma-70 region 2 K03088 - - 0.0000000000000000000000001835 111.0
HKD1_k127_78255_12 Protein conserved in bacteria - - - 0.0000000000000004056 93.0
HKD1_k127_78255_13 Bacterial Ig-like domain 2 - - - 0.0000000000001856 83.0
HKD1_k127_78255_14 Domain of Unknown Function (DUF350) - - - 0.00000000007678 66.0
HKD1_k127_78255_15 - - - - 0.0000000005323 64.0
HKD1_k127_78255_16 Carboxypeptidase regulatory-like domain - - - 0.0000000007378 73.0
HKD1_k127_78255_17 - - - - 0.0000002981 59.0
HKD1_k127_78255_2 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 476.0
HKD1_k127_78255_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 475.0
HKD1_k127_78255_4 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
HKD1_k127_78255_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 398.0
HKD1_k127_78255_6 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 396.0
HKD1_k127_78255_7 Helix-turn-helix domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 353.0
HKD1_k127_78255_8 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 335.0
HKD1_k127_78255_9 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000000000003913 139.0
HKD1_k127_7868602_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.843e-237 759.0
HKD1_k127_7868602_1 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 477.0
HKD1_k127_7868602_10 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HKD1_k127_7868602_11 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000003743 158.0
HKD1_k127_7868602_12 nitric oxide dioxygenase activity K17247 - - 0.00000000000000000000000000000000000000004758 164.0
HKD1_k127_7868602_13 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000001382 148.0
HKD1_k127_7868602_14 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000002645 131.0
HKD1_k127_7868602_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 427.0
HKD1_k127_7868602_3 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 428.0
HKD1_k127_7868602_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 411.0
HKD1_k127_7868602_5 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
HKD1_k127_7868602_6 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001424 272.0
HKD1_k127_7868602_7 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
HKD1_k127_7868602_8 methyltransferase K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
HKD1_k127_7868602_9 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
HKD1_k127_7958219_0 efflux transmembrane transporter activity - - - 9.959e-222 717.0
HKD1_k127_7958219_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 451.0
HKD1_k127_7958219_10 YjbR - - - 0.000000000000004369 81.0
HKD1_k127_7958219_12 SusD family K21572 - - 0.000003097 59.0
HKD1_k127_7958219_13 Copper binding proteins, plastocyanin/azurin family - - - 0.00002192 55.0
HKD1_k127_7958219_14 Serine aminopeptidase, S33 - - - 0.0005704 48.0
HKD1_k127_7958219_2 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 425.0
HKD1_k127_7958219_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 361.0
HKD1_k127_7958219_4 chlorophyll binding K02557,K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HKD1_k127_7958219_5 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001582 229.0
HKD1_k127_7958219_7 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000009207 171.0
HKD1_k127_7958219_8 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000003355 126.0
HKD1_k127_7958219_9 Protein conserved in bacteria - - - 0.00000000000000000001153 99.0
HKD1_k127_7967088_0 Dehydrogenase - - - 3.073e-318 984.0
HKD1_k127_7967088_1 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 471.0
HKD1_k127_7967088_10 DinB family - - - 0.0000000000000000007268 96.0
HKD1_k127_7967088_2 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 354.0
HKD1_k127_7967088_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003161 300.0
HKD1_k127_7967088_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002857 256.0
HKD1_k127_7967088_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000217 209.0
HKD1_k127_7967088_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000009297 206.0
HKD1_k127_7967088_7 Yip1 domain - - - 0.000000000000000000000000000005402 129.0
HKD1_k127_7967088_8 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000000000000004056 100.0
HKD1_k127_805584_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 423.0
HKD1_k127_805584_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000002837 227.0
HKD1_k127_805584_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000002939 226.0
HKD1_k127_846545_0 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 548.0
HKD1_k127_846545_1 Ammonium Transporter Family K03320,K06580 - - 0.0000000000000000000000000000000000000000000000000000004606 195.0
HKD1_k127_846545_2 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000001339 180.0
HKD1_k127_846545_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000001434 164.0
HKD1_k127_874162_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 505.0
HKD1_k127_874162_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001707 252.0
HKD1_k127_874162_2 - - - - 0.000000000000679 76.0