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Overview

ID MAG01741
Name HKD1_bin.59
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family 2-12-FULL-66-21
Genus
Species
Assembly information
Completeness (%) 92.31
Contamination (%) 4.75
GC content (%) 65.0
N50 (bp) 44,375
Genome size (bp) 6,081,391

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4757

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1004171_0 - - - - 0.000000000000000000000000000000000000000000000000000000001227 216.0
HKD1_k127_1004171_1 - - - - 0.000000000000000000000007722 113.0
HKD1_k127_1004171_3 - - - - 0.000002983 57.0
HKD1_k127_1004171_4 cAMP biosynthetic process - - - 0.00008218 50.0
HKD1_k127_1004171_5 Hep Hag repeat protein K08961 - 4.2.2.20,4.2.2.21 0.00009656 54.0
HKD1_k127_1015379_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.06e-286 911.0
HKD1_k127_1015379_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.036e-243 771.0
HKD1_k127_1015379_10 6 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 389.0
HKD1_k127_1015379_11 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 373.0
HKD1_k127_1015379_12 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 374.0
HKD1_k127_1015379_13 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 369.0
HKD1_k127_1015379_14 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 353.0
HKD1_k127_1015379_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 372.0
HKD1_k127_1015379_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 337.0
HKD1_k127_1015379_17 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000002036 273.0
HKD1_k127_1015379_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005383 268.0
HKD1_k127_1015379_19 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001002 261.0
HKD1_k127_1015379_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 604.0
HKD1_k127_1015379_20 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006054 247.0
HKD1_k127_1015379_21 Putative bacterial lipoprotein (DUF799) - - - 0.000000000000000000000000000000000000000000000000000000000000000001199 232.0
HKD1_k127_1015379_22 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000001212 229.0
HKD1_k127_1015379_23 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000007651 197.0
HKD1_k127_1015379_24 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000001281 205.0
HKD1_k127_1015379_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000004816 169.0
HKD1_k127_1015379_26 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000001155 166.0
HKD1_k127_1015379_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000003885 149.0
HKD1_k127_1015379_28 Cytochrome C assembly protein - - - 0.000000000000000000000000000000003615 139.0
HKD1_k127_1015379_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000005836 123.0
HKD1_k127_1015379_3 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 570.0
HKD1_k127_1015379_30 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000006682 107.0
HKD1_k127_1015379_31 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000159 68.0
HKD1_k127_1015379_32 von Willebrand factor type A domain K07114 - - 0.0000000007877 70.0
HKD1_k127_1015379_33 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000004304 62.0
HKD1_k127_1015379_34 Response regulator, receiver - - - 0.0002773 49.0
HKD1_k127_1015379_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 510.0
HKD1_k127_1015379_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 483.0
HKD1_k127_1015379_6 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 459.0
HKD1_k127_1015379_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 416.0
HKD1_k127_1015379_8 PFAM Response regulator receiver domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 417.0
HKD1_k127_1015379_9 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 404.0
HKD1_k127_1021798_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1613.0
HKD1_k127_1021798_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 474.0
HKD1_k127_1021798_10 Glycogen debranching enzyme - - - 0.000000000000000000000000000000005449 146.0
HKD1_k127_1021798_11 - - - - 0.0000001259 62.0
HKD1_k127_1021798_12 Antibiotic biosynthesis monooxygenase - - - 0.000002584 54.0
HKD1_k127_1021798_2 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 477.0
HKD1_k127_1021798_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 409.0
HKD1_k127_1021798_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 392.0
HKD1_k127_1021798_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 260.0
HKD1_k127_1021798_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000009172 259.0
HKD1_k127_1021798_7 Gaf domain K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000001466 193.0
HKD1_k127_1021798_8 - - - - 0.000000000000000000000000000000000000000000998 165.0
HKD1_k127_1021798_9 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000005671 153.0
HKD1_k127_1042179_0 iron assimilation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 559.0
HKD1_k127_1042179_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 525.0
HKD1_k127_1042179_10 - - - - 0.00000000000000000007025 90.0
HKD1_k127_1042179_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 494.0
HKD1_k127_1042179_3 Glycoside hydrolase family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 497.0
HKD1_k127_1042179_4 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 381.0
HKD1_k127_1042179_5 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 346.0
HKD1_k127_1042179_6 catalase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005475 269.0
HKD1_k127_1042179_7 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000009514 187.0
HKD1_k127_1042179_8 DinB family - - - 0.000000000000000000000000000000000000005704 153.0
HKD1_k127_1042179_9 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000007925 108.0
HKD1_k127_1051019_0 PFAM Type II secretion system protein E K02652 - - 3.578e-229 721.0
HKD1_k127_1051019_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 306.0
HKD1_k127_1051019_2 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 315.0
HKD1_k127_1051019_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000009632 167.0
HKD1_k127_1051019_4 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000001113 138.0
HKD1_k127_1051019_5 Type II secretion system protein G K02456 - - 0.000000000000000000000000000000001504 135.0
HKD1_k127_1051019_6 Pilus assembly protein K02662 - - 0.0000000006219 70.0
HKD1_k127_1051019_7 - - - - 0.000000005393 64.0
HKD1_k127_1051019_8 PFAM Fimbrial assembly family protein K02663 - - 0.000003917 58.0
HKD1_k127_1051019_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00008707 52.0
HKD1_k127_1084237_0 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005437 238.0
HKD1_k127_1084237_1 Acyltransferase family - - - 0.000001744 59.0
HKD1_k127_1094177_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 2.564e-196 632.0
HKD1_k127_1094177_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 509.0
HKD1_k127_1094177_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 492.0
HKD1_k127_1094177_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 393.0
HKD1_k127_1094177_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 376.0
HKD1_k127_1094177_5 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 344.0
HKD1_k127_1094177_6 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000001322 219.0
HKD1_k127_1094177_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000002584 123.0
HKD1_k127_1094177_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000001005 123.0
HKD1_k127_1121691_0 AAA domain K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 604.0
HKD1_k127_1121691_1 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 515.0
HKD1_k127_1121691_10 Arsenical resistance operon trans-acting repressor arsD - - - 0.00003242 49.0
HKD1_k127_1121691_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000036 225.0
HKD1_k127_1121691_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000002144 194.0
HKD1_k127_1121691_4 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000002266 175.0
HKD1_k127_1121691_5 - - - - 0.0000000000000000000000000000000000007486 155.0
HKD1_k127_1121691_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000001147 114.0
HKD1_k127_1121691_7 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000002275 119.0
HKD1_k127_1121691_8 - - - - 0.000000000001834 79.0
HKD1_k127_1121691_9 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000008757 61.0
HKD1_k127_1123296_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.483e-312 974.0
HKD1_k127_1123296_1 efflux transmembrane transporter activity - - - 1.97e-301 938.0
HKD1_k127_1123296_10 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 462.0
HKD1_k127_1123296_11 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 413.0
HKD1_k127_1123296_12 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 382.0
HKD1_k127_1123296_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 342.0
HKD1_k127_1123296_14 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 346.0
HKD1_k127_1123296_15 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
HKD1_k127_1123296_16 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 301.0
HKD1_k127_1123296_17 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HKD1_k127_1123296_18 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
HKD1_k127_1123296_19 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005387 263.0
HKD1_k127_1123296_2 MacB-like periplasmic core domain - - - 1.909e-287 915.0
HKD1_k127_1123296_20 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000001425 241.0
HKD1_k127_1123296_21 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000001402 219.0
HKD1_k127_1123296_22 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000002044 189.0
HKD1_k127_1123296_23 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000006736 189.0
HKD1_k127_1123296_24 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000003397 175.0
HKD1_k127_1123296_25 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000008877 168.0
HKD1_k127_1123296_26 DinB family - - - 0.0000000000000000000000000000000000000000001516 164.0
HKD1_k127_1123296_27 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000001732 164.0
HKD1_k127_1123296_28 methyltransferase activity - - - 0.000000000000000000000000000000000000000003138 167.0
HKD1_k127_1123296_29 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000005114 157.0
HKD1_k127_1123296_3 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 6.242e-269 850.0
HKD1_k127_1123296_30 DinB family - - - 0.0000000000000000000000000000000000000002457 154.0
HKD1_k127_1123296_31 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000004714 127.0
HKD1_k127_1123296_32 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000002686 117.0
HKD1_k127_1123296_33 AntiSigma factor - - - 0.0000000000000000000000001958 118.0
HKD1_k127_1123296_34 Protein of unknown function (DUF1697) - - - 0.000000000000000000000001283 115.0
HKD1_k127_1123296_35 Lysin motif - - - 0.000000000000000000000005015 107.0
HKD1_k127_1123296_36 - - - - 0.00000000000000000003635 102.0
HKD1_k127_1123296_37 ThiS family K03636 - - 0.0000000000000000001298 96.0
HKD1_k127_1123296_38 Pfam Activator of Hsp90 ATPase - - - 0.000000000000001453 82.0
HKD1_k127_1123296_39 - - - - 0.000000000000008189 81.0
HKD1_k127_1123296_4 Beta-lactamase - - - 9.813e-231 733.0
HKD1_k127_1123296_41 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000000193 66.0
HKD1_k127_1123296_42 Helix-turn-helix domain K15539 - - 0.000001357 60.0
HKD1_k127_1123296_5 Insulinase (Peptidase family M16) K07263 - - 1.033e-215 702.0
HKD1_k127_1123296_6 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 622.0
HKD1_k127_1123296_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 549.0
HKD1_k127_1123296_8 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 482.0
HKD1_k127_1123296_9 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 438.0
HKD1_k127_1127245_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.963e-229 734.0
HKD1_k127_1127245_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 603.0
HKD1_k127_1127245_10 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 423.0
HKD1_k127_1127245_11 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 424.0
HKD1_k127_1127245_12 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 420.0
HKD1_k127_1127245_13 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 408.0
HKD1_k127_1127245_14 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 393.0
HKD1_k127_1127245_15 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 373.0
HKD1_k127_1127245_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 358.0
HKD1_k127_1127245_17 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 346.0
HKD1_k127_1127245_18 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 346.0
HKD1_k127_1127245_19 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 349.0
HKD1_k127_1127245_2 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 559.0
HKD1_k127_1127245_20 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 308.0
HKD1_k127_1127245_21 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000039 287.0
HKD1_k127_1127245_22 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 311.0
HKD1_k127_1127245_23 peptidase activity, acting on L-amino acid peptides K14647,K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004831 300.0
HKD1_k127_1127245_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009521 247.0
HKD1_k127_1127245_25 synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000186 249.0
HKD1_k127_1127245_26 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000001109 240.0
HKD1_k127_1127245_27 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000075 238.0
HKD1_k127_1127245_28 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000006321 227.0
HKD1_k127_1127245_29 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000001642 233.0
HKD1_k127_1127245_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 566.0
HKD1_k127_1127245_30 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000004116 220.0
HKD1_k127_1127245_31 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001287 210.0
HKD1_k127_1127245_32 PFAM Type II secretion system F K12510 - - 0.000000000000000000000000000000000000000000000000000000003625 212.0
HKD1_k127_1127245_33 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000008278 216.0
HKD1_k127_1127245_34 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000002603 204.0
HKD1_k127_1127245_35 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000000008754 203.0
HKD1_k127_1127245_36 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000009191 187.0
HKD1_k127_1127245_37 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000001488 182.0
HKD1_k127_1127245_38 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000002385 195.0
HKD1_k127_1127245_39 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000001619 182.0
HKD1_k127_1127245_4 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 546.0
HKD1_k127_1127245_40 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000000006585 184.0
HKD1_k127_1127245_41 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000007042 177.0
HKD1_k127_1127245_42 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000001745 168.0
HKD1_k127_1127245_43 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000003097 184.0
HKD1_k127_1127245_44 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000003177 169.0
HKD1_k127_1127245_45 - - - - 0.00000000000000000000000000000000000000000007297 166.0
HKD1_k127_1127245_46 hydrolase of the alpha beta K07018 - - 0.0000000000000000000000000000000000000000001131 166.0
HKD1_k127_1127245_47 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000000001812 166.0
HKD1_k127_1127245_48 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000005923 158.0
HKD1_k127_1127245_49 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000001379 149.0
HKD1_k127_1127245_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 511.0
HKD1_k127_1127245_50 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000007959 151.0
HKD1_k127_1127245_51 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000006035 144.0
HKD1_k127_1127245_52 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000006948 137.0
HKD1_k127_1127245_53 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000001203 123.0
HKD1_k127_1127245_54 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000008108 121.0
HKD1_k127_1127245_55 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000004558 110.0
HKD1_k127_1127245_56 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000001296 116.0
HKD1_k127_1127245_57 regulation of translation K03530 - - 0.000000000000000000005705 95.0
HKD1_k127_1127245_58 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.00000000000000000002215 93.0
HKD1_k127_1127245_59 Smr domain - - - 0.00000000000000000005144 93.0
HKD1_k127_1127245_6 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 496.0
HKD1_k127_1127245_60 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000008471 93.0
HKD1_k127_1127245_61 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000002244 92.0
HKD1_k127_1127245_62 - - - - 0.0000000000000006927 87.0
HKD1_k127_1127245_63 Ndr family - - - 0.00000000000009079 81.0
HKD1_k127_1127245_64 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000003753 70.0
HKD1_k127_1127245_65 FHA domain - - - 0.0000000000004547 74.0
HKD1_k127_1127245_66 peptidyl-tyrosine sulfation - - - 0.0000009605 60.0
HKD1_k127_1127245_67 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000003435 58.0
HKD1_k127_1127245_68 PFAM response regulator receiver K02282 - - 0.0004874 46.0
HKD1_k127_1127245_7 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 441.0
HKD1_k127_1127245_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 449.0
HKD1_k127_1127245_9 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 443.0
HKD1_k127_1128764_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 380.0
HKD1_k127_1128764_1 D-xylose transmembrane transport K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 349.0
HKD1_k127_1128764_10 Cro/C1-type HTH DNA-binding domain K07729 - - 0.0000000000000002225 80.0
HKD1_k127_1128764_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000005042 64.0
HKD1_k127_1128764_12 Putative prokaryotic signal transducing protein - - - 0.00003554 49.0
HKD1_k127_1128764_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 334.0
HKD1_k127_1128764_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 283.0
HKD1_k127_1128764_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000003504 248.0
HKD1_k127_1128764_5 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000004058 248.0
HKD1_k127_1128764_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000002355 215.0
HKD1_k127_1128764_7 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000008168 108.0
HKD1_k127_1128764_9 Phage integrase family - - - 0.0000000000000000007755 95.0
HKD1_k127_1131848_0 Involved in the tonB-independent uptake of proteins - - - 1.266e-233 742.0
HKD1_k127_1131848_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 531.0
HKD1_k127_1131848_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0002863 53.0
HKD1_k127_1131848_2 Glycosyl hydrolases family 32 K03332 - 3.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 527.0
HKD1_k127_1131848_3 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 430.0
HKD1_k127_1131848_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 350.0
HKD1_k127_1131848_5 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000008865 206.0
HKD1_k127_1131848_6 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000001975 177.0
HKD1_k127_1131848_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000002817 159.0
HKD1_k127_1131848_8 - - - - 0.000000000000000000000000005871 124.0
HKD1_k127_1131848_9 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.0000000000000000000000002876 111.0
HKD1_k127_1142362_0 Putative glucoamylase K13688 - - 0.0 2363.0
HKD1_k127_1142362_1 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 546.0
HKD1_k127_1142362_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 409.0
HKD1_k127_1142362_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 394.0
HKD1_k127_1142362_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 300.0
HKD1_k127_1142362_5 ATP:ADP antiporter activity K01932,K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003378 302.0
HKD1_k127_1142362_6 - - - - 0.0000000000000000000000000006478 113.0
HKD1_k127_1142362_8 PFAM Surface antigen variable number repeat K07277 - - 0.0000008131 61.0
HKD1_k127_1142362_9 - - - - 0.00004956 48.0
HKD1_k127_1143853_0 Cytochrome c-type biogenesis protein K02198 - - 3.387e-233 745.0
HKD1_k127_1143853_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 379.0
HKD1_k127_1143853_10 - - - - 0.00000009415 61.0
HKD1_k127_1143853_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
HKD1_k127_1143853_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
HKD1_k127_1143853_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000007382 217.0
HKD1_k127_1143853_5 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000008452 199.0
HKD1_k127_1143853_6 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000125 167.0
HKD1_k127_1143853_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000001396 126.0
HKD1_k127_1143853_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000003945 115.0
HKD1_k127_1145979_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 6.045e-286 901.0
HKD1_k127_1145979_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.206e-260 810.0
HKD1_k127_1145979_10 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 490.0
HKD1_k127_1145979_11 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 454.0
HKD1_k127_1145979_12 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 433.0
HKD1_k127_1145979_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 453.0
HKD1_k127_1145979_14 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 415.0
HKD1_k127_1145979_15 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 406.0
HKD1_k127_1145979_16 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 396.0
HKD1_k127_1145979_17 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 381.0
HKD1_k127_1145979_18 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 362.0
HKD1_k127_1145979_19 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 357.0
HKD1_k127_1145979_2 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.057e-237 762.0
HKD1_k127_1145979_20 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 343.0
HKD1_k127_1145979_21 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 322.0
HKD1_k127_1145979_22 HMGL-like K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 325.0
HKD1_k127_1145979_23 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 282.0
HKD1_k127_1145979_24 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002416 276.0
HKD1_k127_1145979_25 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001704 265.0
HKD1_k127_1145979_26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
HKD1_k127_1145979_27 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000003977 218.0
HKD1_k127_1145979_28 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000008965 244.0
HKD1_k127_1145979_29 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000000000056 199.0
HKD1_k127_1145979_3 Protein of unknown function, DUF255 K06888 - - 7.597e-211 683.0
HKD1_k127_1145979_30 PHP domain K04477 - - 0.00000000000000000000000000000000000000000000000004279 193.0
HKD1_k127_1145979_31 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000008394 182.0
HKD1_k127_1145979_32 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000002178 162.0
HKD1_k127_1145979_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000008137 142.0
HKD1_k127_1145979_34 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000375 136.0
HKD1_k127_1145979_35 Hydrogenase maturation protease - - - 0.0000000000000000000000000005474 118.0
HKD1_k127_1145979_36 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000002582 114.0
HKD1_k127_1145979_37 ABC-type Na efflux pump, permease K01992 - - 0.000000000000000000000002751 115.0
HKD1_k127_1145979_38 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000005575 110.0
HKD1_k127_1145979_39 Transposase and inactivated derivatives - - - 0.0000000000000000000001224 109.0
HKD1_k127_1145979_4 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 2.044e-209 655.0
HKD1_k127_1145979_40 Virulence factor BrkB K07058 - - 0.00000000000000000001287 103.0
HKD1_k127_1145979_41 carboxylase K01968 - 6.4.1.4 0.000000000000000001447 91.0
HKD1_k127_1145979_42 Protein of unknown function (DUF3485) - - - 0.0000000000000006415 79.0
HKD1_k127_1145979_43 Protein conserved in bacteria K15539 - - 0.000000008412 65.0
HKD1_k127_1145979_44 PLD-like domain - - - 0.0000006288 62.0
HKD1_k127_1145979_46 - K01992 - - 0.00003431 57.0
HKD1_k127_1145979_47 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00004389 46.0
HKD1_k127_1145979_5 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 3.096e-199 631.0
HKD1_k127_1145979_6 TIGRFAM YidE YbjL duplication K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 590.0
HKD1_k127_1145979_7 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 535.0
HKD1_k127_1145979_8 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 501.0
HKD1_k127_1145979_9 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 526.0
HKD1_k127_1148300_0 MacB-like periplasmic core domain - - - 2.174e-312 977.0
HKD1_k127_1148300_1 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 576.0
HKD1_k127_1148300_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005764 266.0
HKD1_k127_1148300_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001013 101.0
HKD1_k127_1148300_4 PFAM glucose-methanol-choline oxidoreductase - - - 0.000000000000000149 79.0
HKD1_k127_1148300_5 DNA-templated transcription, initiation K03088 - - 0.0000003795 54.0
HKD1_k127_1150714_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.889e-208 656.0
HKD1_k127_1150714_1 homocysteine K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
HKD1_k127_1152259_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 261.0
HKD1_k127_1152259_1 Putative porin - - - 0.00000000000000000000000000000002531 142.0
HKD1_k127_1178869_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1176.0
HKD1_k127_1178869_1 TonB-dependent Receptor Plug Domain - - - 2.876e-264 849.0
HKD1_k127_1178869_2 Periplasmic copper-binding protein (NosD) - - - 1.157e-241 760.0
HKD1_k127_1178869_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704,GO:1901575 4.2.1.8 2.346e-199 627.0
HKD1_k127_1178869_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 481.0
HKD1_k127_1178869_5 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 340.0
HKD1_k127_1178869_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 303.0
HKD1_k127_1185099_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.62e-283 898.0
HKD1_k127_1185099_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.622e-272 857.0
HKD1_k127_1185099_10 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 302.0
HKD1_k127_1185099_11 S4 RNA-binding domain K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 295.0
HKD1_k127_1185099_12 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002786 272.0
HKD1_k127_1185099_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005412 255.0
HKD1_k127_1185099_14 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001408 262.0
HKD1_k127_1185099_15 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000001517 220.0
HKD1_k127_1185099_16 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000006278 216.0
HKD1_k127_1185099_17 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000004572 207.0
HKD1_k127_1185099_18 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000001478 181.0
HKD1_k127_1185099_19 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001534 174.0
HKD1_k127_1185099_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.963e-232 732.0
HKD1_k127_1185099_20 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000002511 180.0
HKD1_k127_1185099_21 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000008163 165.0
HKD1_k127_1185099_22 pfam nudix K01515 - 3.6.1.13 0.0000000000000000000000000000000000000004509 154.0
HKD1_k127_1185099_23 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000003983 150.0
HKD1_k127_1185099_24 BioY family K03523 - - 0.0000000000000000000000000000000000512 150.0
HKD1_k127_1185099_25 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000001255 132.0
HKD1_k127_1185099_26 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001247 124.0
HKD1_k127_1185099_27 Belongs to the Fur family K03711 - - 0.0000000000000000000000000003676 126.0
HKD1_k127_1185099_28 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000006663 89.0
HKD1_k127_1185099_29 HAD-hyrolase-like K01560 - 3.8.1.2 0.0000000000000271 82.0
HKD1_k127_1185099_3 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 554.0
HKD1_k127_1185099_30 MoaE protein K03635,K03636,K03637,K03752,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.77,2.8.1.12,4.6.1.17 0.000000000001358 70.0
HKD1_k127_1185099_31 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.00000003414 64.0
HKD1_k127_1185099_32 FAD dependent oxidoreductase K19813 - 1.1.5.9 0.0001822 52.0
HKD1_k127_1185099_4 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 572.0
HKD1_k127_1185099_5 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 499.0
HKD1_k127_1185099_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 469.0
HKD1_k127_1185099_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 453.0
HKD1_k127_1185099_8 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 418.0
HKD1_k127_1185099_9 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 357.0
HKD1_k127_1191118_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HKD1_k127_1191118_1 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 310.0
HKD1_k127_1191118_2 spore germination K03605 - - 0.0000000002227 70.0
HKD1_k127_1217293_0 Carbohydrate-selective porin, OprB family K16079,K16080 - - 4.043e-207 661.0
HKD1_k127_1217293_1 Pfam Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 610.0
HKD1_k127_1217293_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000002837 207.0
HKD1_k127_1217293_11 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000002035 185.0
HKD1_k127_1217293_12 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000008892 187.0
HKD1_k127_1217293_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000000947 165.0
HKD1_k127_1217293_14 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000001266 149.0
HKD1_k127_1217293_15 transcriptional regulator - - - 0.00000000000000000000000000000007745 132.0
HKD1_k127_1217293_16 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000002672 135.0
HKD1_k127_1217293_17 - - - - 0.00000000000000000000000000002667 123.0
HKD1_k127_1217293_18 SURF4 family K15977 - - 0.0000000000000000000000000004787 118.0
HKD1_k127_1217293_19 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000009126 108.0
HKD1_k127_1217293_2 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 621.0
HKD1_k127_1217293_20 DinB superfamily - - - 0.000000000000000000000001578 105.0
HKD1_k127_1217293_21 Domain of unknown function (DUF4260) - - - 0.000000000000000000000002013 107.0
HKD1_k127_1217293_22 efflux transmembrane transporter activity - - - 0.0000000000000000004391 89.0
HKD1_k127_1217293_24 cAMP biosynthetic process K18672 - 2.7.7.85 0.00000000000000005529 86.0
HKD1_k127_1217293_25 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000001982 81.0
HKD1_k127_1217293_26 DinB superfamily - - - 0.0000000000000051 78.0
HKD1_k127_1217293_27 Transposase IS200 like - - - 0.0000000000002416 74.0
HKD1_k127_1217293_28 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000005601 75.0
HKD1_k127_1217293_29 Cation efflux family - - - 0.0000000002142 63.0
HKD1_k127_1217293_3 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 503.0
HKD1_k127_1217293_30 Formiminotransferase-cyclodeaminase - - - 0.0000001946 61.0
HKD1_k127_1217293_31 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000005563 50.0
HKD1_k127_1217293_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 432.0
HKD1_k127_1217293_5 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 406.0
HKD1_k127_1217293_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 314.0
HKD1_k127_1217293_7 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
HKD1_k127_1217293_8 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 256.0
HKD1_k127_1217293_9 Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004234 233.0
HKD1_k127_1251059_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.181e-198 623.0
HKD1_k127_1251059_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 299.0
HKD1_k127_1251059_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000003239 54.0
HKD1_k127_1267625_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.377e-236 745.0
HKD1_k127_1267625_1 amino acid K03294 - - 4.236e-214 674.0
HKD1_k127_1267625_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
HKD1_k127_1267625_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000006232 216.0
HKD1_k127_1267625_12 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000969 163.0
HKD1_k127_1267625_13 OmpA family - - - 0.00000000000000000000000000000000000005178 162.0
HKD1_k127_1267625_14 NUDIX domain - - - 0.0000000000000000000000000000000028 140.0
HKD1_k127_1267625_15 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000006816 136.0
HKD1_k127_1267625_16 PFAM AIG2 family protein - - - 0.0000000000000000401 86.0
HKD1_k127_1267625_17 - K01992 - - 0.00000000000001901 83.0
HKD1_k127_1267625_18 - - - - 0.00000000000007099 83.0
HKD1_k127_1267625_19 23S rRNA-intervening sequence protein - - - 0.0000000005572 66.0
HKD1_k127_1267625_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 417.0
HKD1_k127_1267625_3 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 341.0
HKD1_k127_1267625_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 323.0
HKD1_k127_1267625_5 ATPase activity K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 331.0
HKD1_k127_1267625_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 304.0
HKD1_k127_1267625_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 304.0
HKD1_k127_1267625_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
HKD1_k127_1267625_9 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000003536 260.0
HKD1_k127_1323008_0 Carboxypeptidase regulatory-like domain - - - 1e-323 1020.0
HKD1_k127_1323008_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 606.0
HKD1_k127_1323008_10 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 251.0
HKD1_k127_1323008_11 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000102 259.0
HKD1_k127_1323008_12 response to oxidative stress K08368 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000003384 260.0
HKD1_k127_1323008_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000001402 223.0
HKD1_k127_1323008_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000004412 222.0
HKD1_k127_1323008_15 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000006137 201.0
HKD1_k127_1323008_16 FR47-like protein - - - 0.0000000000000000000000000000000000000495 149.0
HKD1_k127_1323008_17 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000001621 139.0
HKD1_k127_1323008_18 - - - - 0.0000000000000000000000004925 114.0
HKD1_k127_1323008_19 Two component regulator propeller - - - 0.00000000000000004494 96.0
HKD1_k127_1323008_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 495.0
HKD1_k127_1323008_20 Papain family cysteine protease - - - 0.000000000000004467 85.0
HKD1_k127_1323008_21 light absorption - - - 0.0000002339 57.0
HKD1_k127_1323008_23 Transposase - - - 0.0000151 51.0
HKD1_k127_1323008_3 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 501.0
HKD1_k127_1323008_4 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 391.0
HKD1_k127_1323008_5 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 368.0
HKD1_k127_1323008_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 367.0
HKD1_k127_1323008_7 region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 291.0
HKD1_k127_1323008_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009945 282.0
HKD1_k127_1323008_9 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001302 250.0
HKD1_k127_1332944_0 DEAD DEAH box helicase K03724 - - 0.0 1511.0
HKD1_k127_1332944_1 Tricorn protease PDZ domain K08676 - - 0.0 1291.0
HKD1_k127_1332944_10 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 536.0
HKD1_k127_1332944_11 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 526.0
HKD1_k127_1332944_12 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 513.0
HKD1_k127_1332944_13 Rubrerythrin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 514.0
HKD1_k127_1332944_14 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 487.0
HKD1_k127_1332944_15 LUD domain K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 438.0
HKD1_k127_1332944_16 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 408.0
HKD1_k127_1332944_17 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 410.0
HKD1_k127_1332944_18 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 383.0
HKD1_k127_1332944_19 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 377.0
HKD1_k127_1332944_2 4Fe-4S dicluster domain K00184 - - 0.0 1039.0
HKD1_k127_1332944_20 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 373.0
HKD1_k127_1332944_21 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 343.0
HKD1_k127_1332944_22 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
HKD1_k127_1332944_23 Transposase Tn5 dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
HKD1_k127_1332944_24 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 285.0
HKD1_k127_1332944_25 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000915 261.0
HKD1_k127_1332944_26 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000142 256.0
HKD1_k127_1332944_27 conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001418 272.0
HKD1_k127_1332944_28 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002067 263.0
HKD1_k127_1332944_29 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
HKD1_k127_1332944_3 membrane K07027,K14205 - 2.3.2.3 1.094e-255 813.0
HKD1_k127_1332944_30 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000009506 242.0
HKD1_k127_1332944_31 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000002292 235.0
HKD1_k127_1332944_32 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000008171 220.0
HKD1_k127_1332944_34 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000001627 205.0
HKD1_k127_1332944_35 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000008295 190.0
HKD1_k127_1332944_36 phosphorelay sensor kinase activity K02478,K07704 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000005372 203.0
HKD1_k127_1332944_37 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000005051 192.0
HKD1_k127_1332944_38 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000002595 184.0
HKD1_k127_1332944_39 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000006979 175.0
HKD1_k127_1332944_4 Alpha amylase, catalytic domain - - - 1.859e-246 774.0
HKD1_k127_1332944_40 protein tyrosine kinase activity K03593 - - 0.0000000000000000000000000000000000000000000009158 177.0
HKD1_k127_1332944_41 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000003611 169.0
HKD1_k127_1332944_42 Cytochrome c - - - 0.000000000000000000000000000000000000000000003776 178.0
HKD1_k127_1332944_43 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000004259 155.0
HKD1_k127_1332944_44 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000003593 136.0
HKD1_k127_1332944_45 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000001396 136.0
HKD1_k127_1332944_48 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000003123 94.0
HKD1_k127_1332944_49 LUD domain K00782 - - 0.000000000000000001753 94.0
HKD1_k127_1332944_5 Polysulphide reductase, NrfD K00185 - - 2.283e-227 713.0
HKD1_k127_1332944_50 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000007306 91.0
HKD1_k127_1332944_51 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000003602 75.0
HKD1_k127_1332944_52 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000315 72.0
HKD1_k127_1332944_54 of the alpha beta superfamily - - - 0.000001366 59.0
HKD1_k127_1332944_56 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0001857 51.0
HKD1_k127_1332944_57 Acetyltransferase (GNAT) family - - - 0.0004688 51.0
HKD1_k127_1332944_6 efflux transmembrane transporter activity - - - 2.692e-223 719.0
HKD1_k127_1332944_7 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 582.0
HKD1_k127_1332944_8 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 565.0
HKD1_k127_1332944_9 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 561.0
HKD1_k127_1336787_0 succinate dehydrogenase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 365.0
HKD1_k127_1336787_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000001567 234.0
HKD1_k127_1336787_2 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000008688 176.0
HKD1_k127_1339577_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0 1300.0
HKD1_k127_1339577_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 1.013e-315 981.0
HKD1_k127_1339577_10 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 589.0
HKD1_k127_1339577_100 YbbR-like protein - - - 0.0000000000000000000000000000819 130.0
HKD1_k127_1339577_101 abc transporter atp-binding protein K01990,K09697 - 3.6.3.7 0.0000000000000000000000000001625 124.0
HKD1_k127_1339577_102 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000005025 124.0
HKD1_k127_1339577_103 Methyltransferase domain - - - 0.00000000000000000000000001544 119.0
HKD1_k127_1339577_104 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000001815 114.0
HKD1_k127_1339577_105 polysaccharide biosynthetic process - - - 0.00000000000000000000000002428 125.0
HKD1_k127_1339577_106 PFAM von Willebrand factor type A - - - 0.00000000000000000000000003103 124.0
HKD1_k127_1339577_107 O-Antigen ligase K02847 - - 0.00000000000000000000000006717 123.0
HKD1_k127_1339577_108 cheY-homologous receiver domain - - - 0.00000000000000000000000006847 111.0
HKD1_k127_1339577_109 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000001293 111.0
HKD1_k127_1339577_11 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 592.0
HKD1_k127_1339577_111 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000001775 110.0
HKD1_k127_1339577_112 Domain of unknown function (DUF4340) - - - 0.00000000000000000000002573 114.0
HKD1_k127_1339577_113 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000003276 108.0
HKD1_k127_1339577_114 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000003296 99.0
HKD1_k127_1339577_115 Methyltransferase type 12 - - - 0.0000000000000000000008936 104.0
HKD1_k127_1339577_116 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000002412 96.0
HKD1_k127_1339577_117 Tetratricopeptide repeat - - - 0.000000000000000000003254 102.0
HKD1_k127_1339577_118 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000009482 105.0
HKD1_k127_1339577_119 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000164 100.0
HKD1_k127_1339577_12 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 549.0
HKD1_k127_1339577_121 Glycosyl transferases group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.00000000000000000005182 103.0
HKD1_k127_1339577_122 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000006252 91.0
HKD1_k127_1339577_123 Transport permease protein K01992 - - 0.0000000000000000002555 98.0
HKD1_k127_1339577_124 Glycosyltransferase like family 2 K20444 - - 0.0000000000000003107 92.0
HKD1_k127_1339577_125 membrane protein (DUF2079) - - - 0.00000000000000436 89.0
HKD1_k127_1339577_126 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000002777 87.0
HKD1_k127_1339577_128 Tfp pilus assembly protein FimV - - - 0.0000000000001174 83.0
HKD1_k127_1339577_13 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 526.0
HKD1_k127_1339577_130 Methyltransferase domain - - - 0.000000000002106 78.0
HKD1_k127_1339577_131 Dienelactone hydrolase family - - - 0.00000000000335 76.0
HKD1_k127_1339577_132 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000001916 77.0
HKD1_k127_1339577_133 HPr kinase - - - 0.00000000002274 74.0
HKD1_k127_1339577_134 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000001082 65.0
HKD1_k127_1339577_135 methyltransferase - - - 0.000000000631 64.0
HKD1_k127_1339577_136 - K05826 - - 0.0000000007082 63.0
HKD1_k127_1339577_138 23S rRNA-intervening sequence protein - - - 0.00000001237 64.0
HKD1_k127_1339577_14 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 522.0
HKD1_k127_1339577_140 - - - - 0.0000009224 63.0
HKD1_k127_1339577_141 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000001692 57.0
HKD1_k127_1339577_142 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.00002382 51.0
HKD1_k127_1339577_143 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0001065 53.0
HKD1_k127_1339577_144 - - - - 0.0001428 50.0
HKD1_k127_1339577_145 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0001447 55.0
HKD1_k127_1339577_146 oxidoreductase activity - - - 0.0003442 54.0
HKD1_k127_1339577_148 - - - - 0.000695 46.0
HKD1_k127_1339577_15 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 507.0
HKD1_k127_1339577_16 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 497.0
HKD1_k127_1339577_17 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 512.0
HKD1_k127_1339577_18 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 477.0
HKD1_k127_1339577_19 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 471.0
HKD1_k127_1339577_2 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 7.728e-287 897.0
HKD1_k127_1339577_20 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 474.0
HKD1_k127_1339577_21 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 462.0
HKD1_k127_1339577_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 449.0
HKD1_k127_1339577_23 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 431.0
HKD1_k127_1339577_24 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 417.0
HKD1_k127_1339577_25 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 412.0
HKD1_k127_1339577_26 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 403.0
HKD1_k127_1339577_27 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
HKD1_k127_1339577_28 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 390.0
HKD1_k127_1339577_29 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 384.0
HKD1_k127_1339577_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.853e-279 882.0
HKD1_k127_1339577_30 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 366.0
HKD1_k127_1339577_31 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
HKD1_k127_1339577_32 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 372.0
HKD1_k127_1339577_33 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 356.0
HKD1_k127_1339577_34 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 349.0
HKD1_k127_1339577_35 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HKD1_k127_1339577_36 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 329.0
HKD1_k127_1339577_37 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
HKD1_k127_1339577_38 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 327.0
HKD1_k127_1339577_39 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 309.0
HKD1_k127_1339577_4 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.756e-269 861.0
HKD1_k127_1339577_40 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 313.0
HKD1_k127_1339577_41 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 315.0
HKD1_k127_1339577_42 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 304.0
HKD1_k127_1339577_43 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 306.0
HKD1_k127_1339577_44 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 292.0
HKD1_k127_1339577_45 Threonine alanine tRNA ligase second additional domain protein K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004178 290.0
HKD1_k127_1339577_46 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009653 287.0
HKD1_k127_1339577_47 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
HKD1_k127_1339577_48 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008424 287.0
HKD1_k127_1339577_49 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 279.0
HKD1_k127_1339577_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.508e-269 846.0
HKD1_k127_1339577_50 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006902 267.0
HKD1_k127_1339577_51 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006168 258.0
HKD1_k127_1339577_52 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 262.0
HKD1_k127_1339577_53 PFAM glycosyl transferase group 1 K12995,K13668 - 2.4.1.346,2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000002581 267.0
HKD1_k127_1339577_54 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K18824 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
HKD1_k127_1339577_55 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000005227 256.0
HKD1_k127_1339577_56 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001544 253.0
HKD1_k127_1339577_57 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000003642 259.0
HKD1_k127_1339577_58 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001115 248.0
HKD1_k127_1339577_59 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 254.0
HKD1_k127_1339577_6 Protein kinase domain K12132 - 2.7.11.1 1.561e-236 765.0
HKD1_k127_1339577_60 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000187 251.0
HKD1_k127_1339577_61 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000003286 247.0
HKD1_k127_1339577_62 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000001381 231.0
HKD1_k127_1339577_63 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
HKD1_k127_1339577_64 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001682 241.0
HKD1_k127_1339577_65 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001829 232.0
HKD1_k127_1339577_66 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000001148 224.0
HKD1_k127_1339577_67 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000001322 226.0
HKD1_k127_1339577_68 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000003794 218.0
HKD1_k127_1339577_69 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000002677 220.0
HKD1_k127_1339577_7 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.304e-234 748.0
HKD1_k127_1339577_70 - - - - 0.0000000000000000000000000000000000000000000000000000000009705 219.0
HKD1_k127_1339577_71 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000003372 207.0
HKD1_k127_1339577_72 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000001298 203.0
HKD1_k127_1339577_73 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000003393 220.0
HKD1_k127_1339577_74 - - - - 0.00000000000000000000000000000000000000000000000000000381 197.0
HKD1_k127_1339577_75 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000536 199.0
HKD1_k127_1339577_76 - - - - 0.000000000000000000000000000000000000000000000000000006313 195.0
HKD1_k127_1339577_77 Psort location CytoplasmicMembrane, score K01992 - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD1_k127_1339577_78 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000000365 197.0
HKD1_k127_1339577_79 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000954 190.0
HKD1_k127_1339577_8 Alpha amylase, catalytic domain K01176,K01236 - 3.2.1.1,3.2.1.141 3.626e-205 661.0
HKD1_k127_1339577_80 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000001389 191.0
HKD1_k127_1339577_81 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000004207 187.0
HKD1_k127_1339577_82 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000005114 182.0
HKD1_k127_1339577_83 SLBB domain K01991 - - 0.000000000000000000000000000000000000000000007138 174.0
HKD1_k127_1339577_84 - - - - 0.000000000000000000000000000000000000000000008672 169.0
HKD1_k127_1339577_85 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000003027 170.0
HKD1_k127_1339577_86 - - - - 0.0000000000000000000000000000000000000000001313 163.0
HKD1_k127_1339577_87 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000007905 158.0
HKD1_k127_1339577_88 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000005228 144.0
HKD1_k127_1339577_89 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000008069 156.0
HKD1_k127_1339577_9 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 2.347e-195 632.0
HKD1_k127_1339577_90 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000001892 153.0
HKD1_k127_1339577_91 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000005137 150.0
HKD1_k127_1339577_92 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000001565 136.0
HKD1_k127_1339577_93 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000181 142.0
HKD1_k127_1339577_94 Ribosomal protein L11 methyltransferase (PrmA) K11434 - 2.1.1.319 0.000000000000000000000000000000002044 143.0
HKD1_k127_1339577_95 Methyltransferase type 12 - - - 0.0000000000000000000000000000000237 138.0
HKD1_k127_1339577_96 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000002184 127.0
HKD1_k127_1339577_97 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000003221 132.0
HKD1_k127_1339577_98 - - - - 0.000000000000000000000000000002161 124.0
HKD1_k127_1339577_99 oligosaccharyl transferase activity - - - 0.00000000000000000000000000005391 134.0
HKD1_k127_1351605_0 TonB-dependent receptor - - - 2.102e-225 739.0
HKD1_k127_1351605_1 ASPIC and UnbV - - - 3.296e-211 670.0
HKD1_k127_1351605_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
HKD1_k127_1351605_3 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 413.0
HKD1_k127_1351605_4 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 266.0
HKD1_k127_138781_0 Anion-transporting ATPase K01551 - 3.6.3.16 1.461e-214 681.0
HKD1_k127_138781_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 521.0
HKD1_k127_138781_10 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000163 185.0
HKD1_k127_138781_11 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000000000000000007246 142.0
HKD1_k127_138781_12 Arsenical resistance operon trans-acting repressor arsD - - - 0.000000000000000000000000000008235 122.0
HKD1_k127_138781_13 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000165 115.0
HKD1_k127_138781_14 transcriptional regulator, ArsR family protein K03892 - - 0.0000000000000000000007405 101.0
HKD1_k127_138781_15 Domain of unknown function (DUF378) - - - 0.000000000000000001221 87.0
HKD1_k127_138781_16 PFAM Fasciclin domain K19519 - - 0.000000000000000004171 94.0
HKD1_k127_138781_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000001016 99.0
HKD1_k127_138781_18 - - - - 0.0000000001558 63.0
HKD1_k127_138781_2 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 492.0
HKD1_k127_138781_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 375.0
HKD1_k127_138781_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 361.0
HKD1_k127_138781_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
HKD1_k127_138781_6 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD1_k127_138781_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000001412 190.0
HKD1_k127_138781_8 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000005407 185.0
HKD1_k127_138781_9 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000002409 172.0
HKD1_k127_1430621_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 3.943e-231 731.0
HKD1_k127_1430621_1 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 268.0
HKD1_k127_1430621_2 Dodecin K09165 - - 0.000000000000008124 76.0
HKD1_k127_1467492_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 360.0
HKD1_k127_1467492_1 Outer membrane efflux protein - - - 0.0000005399 62.0
HKD1_k127_147223_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 407.0
HKD1_k127_147223_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 311.0
HKD1_k127_147223_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000007754 222.0
HKD1_k127_147223_3 - - - - 0.0000000000000000000000000000000139 139.0
HKD1_k127_147223_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000001008 109.0
HKD1_k127_147223_5 - - - - 0.000000000000000000000003828 111.0
HKD1_k127_147223_6 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000002194 98.0
HKD1_k127_147223_7 - - - - 0.00000000000000002667 91.0
HKD1_k127_147223_8 Adenylate cyclase K01768 - 4.6.1.1 0.0000008507 51.0
HKD1_k127_1482805_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.509e-271 848.0
HKD1_k127_1482805_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 528.0
HKD1_k127_1482805_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 506.0
HKD1_k127_1482805_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 446.0
HKD1_k127_1482805_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 331.0
HKD1_k127_1482805_5 domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001318 241.0
HKD1_k127_1482805_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002939 218.0
HKD1_k127_1482805_7 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000007522 198.0
HKD1_k127_1482805_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000001833 184.0
HKD1_k127_1482805_9 Protein of unknown function (DUF2905) - - - 0.000000000000004291 76.0
HKD1_k127_1488621_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
HKD1_k127_1488621_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 452.0
HKD1_k127_1488621_10 Iron-sulfur cluster-binding domain - - - 0.0000000000000001836 94.0
HKD1_k127_1488621_11 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000004571 85.0
HKD1_k127_1488621_12 - - - - 0.0000000001829 74.0
HKD1_k127_1488621_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 445.0
HKD1_k127_1488621_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 399.0
HKD1_k127_1488621_4 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000001343 211.0
HKD1_k127_1488621_5 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000005499 183.0
HKD1_k127_1488621_6 HWE histidine kinase - - - 0.0000000000000000000000000000000000000007961 167.0
HKD1_k127_1488621_7 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000005463 141.0
HKD1_k127_1488621_8 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000003769 129.0
HKD1_k127_1488621_9 integral membrane protein - - - 0.00000000000000000000008901 114.0
HKD1_k127_1496944_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 538.0
HKD1_k127_1496944_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 477.0
HKD1_k127_1496944_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 398.0
HKD1_k127_1496944_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 325.0
HKD1_k127_1496944_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003103 243.0
HKD1_k127_1496944_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000002459 181.0
HKD1_k127_1496944_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000001362 169.0
HKD1_k127_1496944_7 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000243 158.0
HKD1_k127_1496944_8 Sporulation and spore germination - - - 0.0000000000000000000001418 108.0
HKD1_k127_1496944_9 endonuclease containing a URI domain K07461 - - 0.000000000000000000002994 100.0
HKD1_k127_15967_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 1.882e-267 828.0
HKD1_k127_15967_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 592.0
HKD1_k127_15967_10 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 390.0
HKD1_k127_15967_11 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 383.0
HKD1_k127_15967_12 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 349.0
HKD1_k127_15967_13 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 347.0
HKD1_k127_15967_14 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001827 279.0
HKD1_k127_15967_15 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006717 273.0
HKD1_k127_15967_16 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
HKD1_k127_15967_17 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
HKD1_k127_15967_18 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002637 275.0
HKD1_k127_15967_19 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000004378 258.0
HKD1_k127_15967_2 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 501.0
HKD1_k127_15967_20 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000005737 249.0
HKD1_k127_15967_21 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000004962 213.0
HKD1_k127_15967_22 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000009821 183.0
HKD1_k127_15967_23 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000005484 187.0
HKD1_k127_15967_24 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000001915 190.0
HKD1_k127_15967_25 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000006816 176.0
HKD1_k127_15967_26 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000003396 173.0
HKD1_k127_15967_27 - - - - 0.0000000000000000000000000000000000000000114 165.0
HKD1_k127_15967_28 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001156 156.0
HKD1_k127_15967_29 PaaD-like protein - - - 0.0000000000000000000000000000000002621 136.0
HKD1_k127_15967_3 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 503.0
HKD1_k127_15967_30 Rrf2 family - - - 0.0000000000000000000000000000000004411 136.0
HKD1_k127_15967_31 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000002437 135.0
HKD1_k127_15967_32 Tetratricopeptide repeat - - - 0.00000000000000000000000006279 121.0
HKD1_k127_15967_33 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000004207 109.0
HKD1_k127_15967_34 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000001961 106.0
HKD1_k127_15967_35 Oxidoreductase FAD-binding domain - - - 0.0000000000000000003808 96.0
HKD1_k127_15967_36 - - - - 0.00000000000000008031 88.0
HKD1_k127_15967_37 - - - - 0.000000000001005 79.0
HKD1_k127_15967_38 Glutaredoxin - - - 0.000000002415 60.0
HKD1_k127_15967_4 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 451.0
HKD1_k127_15967_5 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 442.0
HKD1_k127_15967_6 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 428.0
HKD1_k127_15967_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 425.0
HKD1_k127_15967_8 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 404.0
HKD1_k127_15967_9 Deoxyhypusine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 391.0
HKD1_k127_1602962_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 426.0
HKD1_k127_1602962_1 Flavodoxin-like fold K00355 - 1.6.5.2 0.00000000000000000035 90.0
HKD1_k127_1602962_2 Phospholipid methyltransferase - - - 0.0000000000007855 78.0
HKD1_k127_1604457_0 Amidohydrolase family - - - 5.232e-279 864.0
HKD1_k127_1606421_0 cellulase activity - - - 0.00000000000000000000000000000000004359 141.0
HKD1_k127_1606421_1 cellular response to heat K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000013 79.0
HKD1_k127_1606421_2 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000001989 67.0
HKD1_k127_1629965_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.702e-283 879.0
HKD1_k127_1629965_1 PFAM Glycosyl transferase family 2 - - - 3.022e-195 620.0
HKD1_k127_1629965_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 457.0
HKD1_k127_1629965_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 445.0
HKD1_k127_1629965_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 368.0
HKD1_k127_1629965_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 350.0
HKD1_k127_1629965_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001342 278.0
HKD1_k127_1629965_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000001041 90.0
HKD1_k127_1631147_0 cellulose binding - - - 7.199e-204 646.0
HKD1_k127_1631147_1 RibD C-terminal domain - - - 0.000000000000000000000000000003482 128.0
HKD1_k127_1651985_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 605.0
HKD1_k127_1651985_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000006921 206.0
HKD1_k127_1651985_2 Bacterial Ig-like domain (group 3) - - - 0.000000000000003842 90.0
HKD1_k127_1651985_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000004756 81.0
HKD1_k127_1651985_4 Cytochrome c-type biogenesis protein K02198 - - 0.00000000001717 67.0
HKD1_k127_1651985_5 Pectate lyase K21606 - 3.2.1.202 0.000001733 61.0
HKD1_k127_1663112_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002117 233.0
HKD1_k127_1663112_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000309 150.0
HKD1_k127_1663112_2 COG3209 Rhs family protein - - - 0.000000000000000000000000000000002262 144.0
HKD1_k127_1663112_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000008134 102.0
HKD1_k127_1663112_4 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000187 90.0
HKD1_k127_1663112_5 Cold shock protein domain - - - 0.0000000000002003 73.0
HKD1_k127_1720544_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000004573 136.0
HKD1_k127_1720544_1 Type II transport protein GspH K08084 - - 0.0000001732 60.0
HKD1_k127_1720544_3 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00001041 48.0
HKD1_k127_1720544_4 pilus assembly protein PilW K02672 - - 0.0001025 54.0
HKD1_k127_1744906_0 COGs COG1740 Ni Fe-hydrogenase I small subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 533.0
HKD1_k127_1744906_1 COGs COG0374 Ni Fe-hydrogenase I large subunit K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 478.0
HKD1_k127_1744906_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006884 283.0
HKD1_k127_18251_0 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006224 277.0
HKD1_k127_1837079_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.344e-262 816.0
HKD1_k127_1837079_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 5.433e-244 784.0
HKD1_k127_1837079_10 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
HKD1_k127_1837079_11 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002136 267.0
HKD1_k127_1837079_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 235.0
HKD1_k127_1837079_13 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000006196 224.0
HKD1_k127_1837079_14 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000001929 234.0
HKD1_k127_1837079_15 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000005178 190.0
HKD1_k127_1837079_16 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000001513 139.0
HKD1_k127_1837079_17 Redoxin - - - 0.0000000000000000000000001385 109.0
HKD1_k127_1837079_18 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000001251 100.0
HKD1_k127_1837079_19 AhpC/TSA family - - - 0.000001007 54.0
HKD1_k127_1837079_2 Polysulphide reductase, NrfD K00185 - - 9.124e-208 657.0
HKD1_k127_1837079_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 449.0
HKD1_k127_1837079_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 407.0
HKD1_k127_1837079_5 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 402.0
HKD1_k127_1837079_6 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 368.0
HKD1_k127_1837079_7 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 357.0
HKD1_k127_1837079_8 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 348.0
HKD1_k127_1837079_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 324.0
HKD1_k127_188126_0 Receptor family ligand binding region K01999 - - 1.434e-221 688.0
HKD1_k127_188126_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 559.0
HKD1_k127_188126_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 502.0
HKD1_k127_188126_3 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009951 287.0
HKD1_k127_2016034_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 403.0
HKD1_k127_2016034_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.00000000000000000000000000000000000000000006166 163.0
HKD1_k127_2016034_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000002544 158.0
HKD1_k127_2016034_3 - - - - 0.0000000000000007041 80.0
HKD1_k127_2019771_0 elongation factor Tu domain 2 protein K02355 - - 7.592e-222 708.0
HKD1_k127_2019771_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.209e-221 700.0
HKD1_k127_2019771_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 285.0
HKD1_k127_2019771_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005012 282.0
HKD1_k127_2019771_12 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 278.0
HKD1_k127_2019771_13 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005424 263.0
HKD1_k127_2019771_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000002289 233.0
HKD1_k127_2019771_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000006572 215.0
HKD1_k127_2019771_16 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000329 207.0
HKD1_k127_2019771_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000002782 183.0
HKD1_k127_2019771_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000396 175.0
HKD1_k127_2019771_19 - - - - 0.00000000000000000000000000000000000000000000003422 193.0
HKD1_k127_2019771_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 612.0
HKD1_k127_2019771_20 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000005256 168.0
HKD1_k127_2019771_21 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000001597 134.0
HKD1_k127_2019771_22 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000004478 137.0
HKD1_k127_2019771_23 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000001309 131.0
HKD1_k127_2019771_24 Pfam:N_methyl_2 - - - 0.00000000000000000003285 96.0
HKD1_k127_2019771_25 Helix-hairpin-helix motif - - - 0.000000000000000000332 100.0
HKD1_k127_2019771_26 Pfam:N_methyl_2 - - - 0.0000000000000000006648 93.0
HKD1_k127_2019771_27 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001075 87.0
HKD1_k127_2019771_28 Thioredoxin - - - 0.00000000000000009358 93.0
HKD1_k127_2019771_29 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000007364 80.0
HKD1_k127_2019771_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 540.0
HKD1_k127_2019771_30 Pfam:N_methyl_2 - - - 0.0000000000001541 81.0
HKD1_k127_2019771_31 Ribosomal protein L36 K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002398 64.0
HKD1_k127_2019771_32 Yip1 domain - - - 0.00000000005797 73.0
HKD1_k127_2019771_33 long-chain fatty acid transporting porin activity K06076 - - 0.000000003054 68.0
HKD1_k127_2019771_34 VKc - - - 0.00001484 57.0
HKD1_k127_2019771_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 499.0
HKD1_k127_2019771_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 474.0
HKD1_k127_2019771_6 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 430.0
HKD1_k127_2019771_7 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 324.0
HKD1_k127_2019771_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 318.0
HKD1_k127_2019771_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 296.0
HKD1_k127_2035788_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.029e-292 905.0
HKD1_k127_2035788_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 2.347e-286 898.0
HKD1_k127_2035788_10 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 384.0
HKD1_k127_2035788_11 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 297.0
HKD1_k127_2035788_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004581 246.0
HKD1_k127_2035788_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000277 224.0
HKD1_k127_2035788_14 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000008469 196.0
HKD1_k127_2035788_15 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000322 189.0
HKD1_k127_2035788_16 - - - - 0.0000000000000000000000000000000000000003249 161.0
HKD1_k127_2035788_17 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000009814 141.0
HKD1_k127_2035788_18 Iodothyronine deiodinase - - - 0.00000000000000000000000000001359 121.0
HKD1_k127_2035788_19 - - - - 0.00000000000000000000000000009168 134.0
HKD1_k127_2035788_2 Carboxypeptidase regulatory-like domain - - - 2.482e-286 917.0
HKD1_k127_2035788_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000001473 107.0
HKD1_k127_2035788_21 Stress-responsive transcriptional regulator - - - 0.000000000000005082 76.0
HKD1_k127_2035788_22 Beta-propeller repeat - - - 0.00000000000002227 87.0
HKD1_k127_2035788_23 - - - - 0.0000000000000486 84.0
HKD1_k127_2035788_24 - - - - 0.00000000002823 68.0
HKD1_k127_2035788_25 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000005168 69.0
HKD1_k127_2035788_26 TonB dependent receptor - - - 0.0000039 60.0
HKD1_k127_2035788_27 Kunitz/Bovine pancreatic trypsin inhibitor domain K16628 GO:0001704,GO:0001706,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005581,GO:0005590,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005793,GO:0005798,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006996,GO:0007275,GO:0007369,GO:0007492,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009888,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0022607,GO:0030020,GO:0030134,GO:0030135,GO:0030154,GO:0030198,GO:0030934,GO:0031012,GO:0031090,GO:0031410,GO:0031974,GO:0031982,GO:0032501,GO:0032502,GO:0032991,GO:0033116,GO:0035987,GO:0042802,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048598,GO:0048646,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0061024,GO:0062023,GO:0065003,GO:0070013,GO:0071840,GO:0090114,GO:0097708,GO:0098588,GO:0098644,GO:0098648,GO:0098652,GO:0099080 - 0.0000426 55.0
HKD1_k127_2035788_3 Glucodextranase, domain N K01178 - 3.2.1.3 4.086e-218 698.0
HKD1_k127_2035788_4 Trehalase K01194 - 3.2.1.28 4.21e-205 656.0
HKD1_k127_2035788_5 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 585.0
HKD1_k127_2035788_6 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 543.0
HKD1_k127_2035788_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 479.0
HKD1_k127_2035788_8 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 410.0
HKD1_k127_2035788_9 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 415.0
HKD1_k127_2042766_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1452.0
HKD1_k127_2042766_1 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1239.0
HKD1_k127_2042766_10 Peptidase M56, BlaR1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 316.0
HKD1_k127_2042766_11 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 275.0
HKD1_k127_2042766_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001457 259.0
HKD1_k127_2042766_13 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000009664 236.0
HKD1_k127_2042766_14 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000136 226.0
HKD1_k127_2042766_15 Sigma-54 interaction domain K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000002466 253.0
HKD1_k127_2042766_16 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004488 205.0
HKD1_k127_2042766_17 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000002488 208.0
HKD1_k127_2042766_18 Universal stress protein family - - - 0.000000000000000000000000000000000000004025 154.0
HKD1_k127_2042766_19 Penicillinase repressor - - - 0.0000000000000000000000000000001602 134.0
HKD1_k127_2042766_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 7.896e-211 671.0
HKD1_k127_2042766_20 Winged helix DNA-binding domain - - - 0.000000000000000000000000001867 115.0
HKD1_k127_2042766_21 Subtilase family - - - 0.0000000000000000000000000473 117.0
HKD1_k127_2042766_22 - - - - 0.00000000000000000000000004887 110.0
HKD1_k127_2042766_24 ubiE/COQ5 methyltransferase family - - - 0.000000175 63.0
HKD1_k127_2042766_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 6.975e-194 614.0
HKD1_k127_2042766_4 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 513.0
HKD1_k127_2042766_5 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
HKD1_k127_2042766_6 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 332.0
HKD1_k127_2042766_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 322.0
HKD1_k127_2042766_8 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 338.0
HKD1_k127_2042766_9 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 316.0
HKD1_k127_2048230_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0 1211.0
HKD1_k127_2048230_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 541.0
HKD1_k127_2048230_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 362.0
HKD1_k127_2048230_3 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 376.0
HKD1_k127_2048230_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000002073 161.0
HKD1_k127_2048230_5 VIT family - - - 0.000000000000000000000007836 102.0
HKD1_k127_2049497_0 acetylesterase activity - - - 0.0000000000000000000000000000000000000001139 166.0
HKD1_k127_2049497_1 - - - - 0.0000000000000000000000000000000000000006072 154.0
HKD1_k127_2049497_2 Adenylate cyclase - - - 0.0000000000000000000000000000000001658 141.0
HKD1_k127_2049497_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000005115 122.0
HKD1_k127_2049497_4 PFAM peptidase - - - 0.000000000000641 69.0
HKD1_k127_2055092_0 cellulose binding - - - 0.0 1260.0
HKD1_k127_2055092_1 Sortilin, neurotensin receptor 3, - - - 0.0 1234.0
HKD1_k127_2055092_10 Amidase K01426 - 3.5.1.4 1.864e-194 620.0
HKD1_k127_2055092_11 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 592.0
HKD1_k127_2055092_12 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 605.0
HKD1_k127_2055092_13 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 576.0
HKD1_k127_2055092_14 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 556.0
HKD1_k127_2055092_15 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 558.0
HKD1_k127_2055092_16 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 514.0
HKD1_k127_2055092_17 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 504.0
HKD1_k127_2055092_18 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 465.0
HKD1_k127_2055092_19 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 451.0
HKD1_k127_2055092_2 cellulose binding - - - 0.0 1045.0
HKD1_k127_2055092_20 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 430.0
HKD1_k127_2055092_21 mismatched DNA binding K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 415.0
HKD1_k127_2055092_22 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 392.0
HKD1_k127_2055092_23 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 389.0
HKD1_k127_2055092_24 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 386.0
HKD1_k127_2055092_25 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 366.0
HKD1_k127_2055092_26 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 370.0
HKD1_k127_2055092_27 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 359.0
HKD1_k127_2055092_28 KR domain K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 349.0
HKD1_k127_2055092_29 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 338.0
HKD1_k127_2055092_3 Sortilin, neurotensin receptor 3, - - - 1.567e-312 989.0
HKD1_k127_2055092_30 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 345.0
HKD1_k127_2055092_31 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 357.0
HKD1_k127_2055092_32 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 318.0
HKD1_k127_2055092_33 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 316.0
HKD1_k127_2055092_34 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 302.0
HKD1_k127_2055092_35 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 314.0
HKD1_k127_2055092_36 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002097 295.0
HKD1_k127_2055092_37 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009041 271.0
HKD1_k127_2055092_38 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
HKD1_k127_2055092_39 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006753 242.0
HKD1_k127_2055092_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 5.723e-306 949.0
HKD1_k127_2055092_40 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006337 255.0
HKD1_k127_2055092_41 tRNA m6t6A37 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000104 229.0
HKD1_k127_2055092_42 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
HKD1_k127_2055092_43 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005692 253.0
HKD1_k127_2055092_44 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000006798 230.0
HKD1_k127_2055092_45 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000001966 229.0
HKD1_k127_2055092_46 Single Cache domain 2 K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000003348 238.0
HKD1_k127_2055092_47 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000004501 230.0
HKD1_k127_2055092_48 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000001159 220.0
HKD1_k127_2055092_49 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000006518 220.0
HKD1_k127_2055092_5 Belongs to the UPF0441 family - - - 1.83e-277 883.0
HKD1_k127_2055092_50 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000003774 207.0
HKD1_k127_2055092_51 RNA pseudouridylate synthase K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000001373 207.0
HKD1_k127_2055092_52 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000002343 200.0
HKD1_k127_2055092_53 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000000002205 179.0
HKD1_k127_2055092_54 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000003329 180.0
HKD1_k127_2055092_55 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000005065 162.0
HKD1_k127_2055092_56 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000007459 155.0
HKD1_k127_2055092_57 - - - - 0.0000000000000000000000000000000000000003926 166.0
HKD1_k127_2055092_58 DoxX - - - 0.0000000000000000000000000000000000001608 145.0
HKD1_k127_2055092_59 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000007099 132.0
HKD1_k127_2055092_6 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.038e-275 856.0
HKD1_k127_2055092_60 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000002098 132.0
HKD1_k127_2055092_62 Transglycosylase associated protein - - - 0.00000000000000000000000000003961 118.0
HKD1_k127_2055092_63 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000001046 120.0
HKD1_k127_2055092_64 TIGRFAM VWFA-related Acidobacterial domain K07114 - - 0.00000000000000000000000005442 121.0
HKD1_k127_2055092_65 - - - - 0.0000000000000000000003455 107.0
HKD1_k127_2055092_67 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000002081 90.0
HKD1_k127_2055092_68 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000000002587 88.0
HKD1_k127_2055092_69 GtrA-like protein - - - 0.000000000000005087 83.0
HKD1_k127_2055092_7 lysine biosynthetic process via aminoadipic acid - - - 5.581e-241 771.0
HKD1_k127_2055092_70 Polymer-forming cytoskeletal - - - 0.00000000000006796 80.0
HKD1_k127_2055092_71 Transcriptional regulator - - - 0.00000000003359 67.0
HKD1_k127_2055092_72 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000002832 65.0
HKD1_k127_2055092_73 cheY-homologous receiver domain - - - 0.0000000104 62.0
HKD1_k127_2055092_74 PBS lyase HEAT-like repeat - - - 0.00000001554 66.0
HKD1_k127_2055092_75 - - - - 0.0000001961 65.0
HKD1_k127_2055092_76 TIGRFAM VWFA-related Acidobacterial domain K07114 - - 0.000008615 57.0
HKD1_k127_2055092_77 oxidoreductase activity - - - 0.00001964 57.0
HKD1_k127_2055092_79 - - - - 0.0003099 54.0
HKD1_k127_2055092_8 efflux transmembrane transporter activity - - - 1.564e-206 672.0
HKD1_k127_2055092_9 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 2.249e-202 645.0
HKD1_k127_2058104_0 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 302.0
HKD1_k127_2058104_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000002571 142.0
HKD1_k127_2061467_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1051.0
HKD1_k127_2061467_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 9.363e-294 915.0
HKD1_k127_2061467_10 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 497.0
HKD1_k127_2061467_11 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 475.0
HKD1_k127_2061467_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 466.0
HKD1_k127_2061467_13 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 449.0
HKD1_k127_2061467_14 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 398.0
HKD1_k127_2061467_15 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 387.0
HKD1_k127_2061467_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 356.0
HKD1_k127_2061467_17 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 356.0
HKD1_k127_2061467_18 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 320.0
HKD1_k127_2061467_19 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 300.0
HKD1_k127_2061467_2 serine-type peptidase activity - - - 2.022e-254 815.0
HKD1_k127_2061467_20 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
HKD1_k127_2061467_21 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 301.0
HKD1_k127_2061467_22 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002897 275.0
HKD1_k127_2061467_23 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001049 283.0
HKD1_k127_2061467_24 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005756 269.0
HKD1_k127_2061467_25 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 259.0
HKD1_k127_2061467_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002009 259.0
HKD1_k127_2061467_27 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008789 253.0
HKD1_k127_2061467_28 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000001348 210.0
HKD1_k127_2061467_29 - - - - 0.000000000000000000000000000000000000000000000000007239 190.0
HKD1_k127_2061467_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.901e-250 792.0
HKD1_k127_2061467_30 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000001805 182.0
HKD1_k127_2061467_31 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000000000000084 165.0
HKD1_k127_2061467_32 - - - - 0.0000000000000000000000000000000000000002415 163.0
HKD1_k127_2061467_33 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000007325 149.0
HKD1_k127_2061467_34 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000113 154.0
HKD1_k127_2061467_35 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000005769 141.0
HKD1_k127_2061467_36 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.000000000000000000000000000000004107 133.0
HKD1_k127_2061467_37 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.000000000000000000000000000000009727 132.0
HKD1_k127_2061467_38 CYTH K05873 - 4.6.1.1 0.00000000000000000000006807 105.0
HKD1_k127_2061467_39 2 iron, 2 sulfur cluster binding K13643 - - 0.0000000000000000000005382 101.0
HKD1_k127_2061467_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.083e-213 670.0
HKD1_k127_2061467_40 Endoribonuclease L-PSP - - - 0.000000000000000000007915 98.0
HKD1_k127_2061467_41 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000009287 98.0
HKD1_k127_2061467_42 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'- monophosphates containing purine bases are preferred to those containing pyrimidine bases - GO:0001558,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030307,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040008,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045927,GO:0046434,GO:0046483,GO:0046700,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0055086,GO:0065007,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000002807 78.0
HKD1_k127_2061467_43 Bacterial regulatory proteins, tetR family K22108 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000005693 78.0
HKD1_k127_2061467_44 PrcB C-terminal - - - 0.0000000000007579 77.0
HKD1_k127_2061467_46 Domain of unknown function (DUF4870) - - - 0.00000007542 63.0
HKD1_k127_2061467_47 Peptidase_C39 like family - - - 0.000002406 61.0
HKD1_k127_2061467_48 23S rRNA-intervening sequence protein - - - 0.000002807 51.0
HKD1_k127_2061467_49 Protein of unknown function (DUF2934) - - - 0.00006777 50.0
HKD1_k127_2061467_5 Cytochrome c - - - 1.238e-196 621.0
HKD1_k127_2061467_50 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.0005623 44.0
HKD1_k127_2061467_6 Thiolase, C-terminal domain - - - 3.554e-195 614.0
HKD1_k127_2061467_7 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 555.0
HKD1_k127_2061467_8 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 537.0
HKD1_k127_2061467_9 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 508.0
HKD1_k127_2061694_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 452.0
HKD1_k127_2061694_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 346.0
HKD1_k127_2061694_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000001055 258.0
HKD1_k127_2061694_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000009236 149.0
HKD1_k127_2061694_4 PFAM O-methyltransferase - - - 0.000000000000000000000000000009509 126.0
HKD1_k127_2061694_5 cheY-homologous receiver domain - - - 0.0000000000001845 74.0
HKD1_k127_2061694_6 ATP-binding region ATPase domain protein - - - 0.00001163 54.0
HKD1_k127_2075577_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 388.0
HKD1_k127_2075577_1 general secretion pathway protein K02456,K02650 - - 0.0000000000000000002188 100.0
HKD1_k127_2075577_2 PFAM Ig domain protein group 1 domain protein - - - 0.000003836 57.0
HKD1_k127_2090089_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 628.0
HKD1_k127_2090089_1 - - - - 0.000000001998 61.0
HKD1_k127_2099067_0 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000008668 141.0
HKD1_k127_2102168_0 phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 606.0
HKD1_k127_2102168_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 424.0
HKD1_k127_2134649_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 452.0
HKD1_k127_2134649_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000006849 146.0
HKD1_k127_2134649_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000001493 136.0
HKD1_k127_2134649_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000001305 58.0
HKD1_k127_2153913_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 477.0
HKD1_k127_2153913_1 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000004499 241.0
HKD1_k127_2153913_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000001389 166.0
HKD1_k127_2153913_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000001167 88.0
HKD1_k127_216321_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.607e-231 727.0
HKD1_k127_216321_1 Glycosyl hydrolases family 2, TIM barrel domain - - - 2.266e-222 706.0
HKD1_k127_216321_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 568.0
HKD1_k127_216321_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 400.0
HKD1_k127_216321_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
HKD1_k127_216321_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007774 260.0
HKD1_k127_216321_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000001727 183.0
HKD1_k127_216321_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000002295 96.0
HKD1_k127_216321_8 serine-type endopeptidase activity K20276 - - 0.000000000000003992 84.0
HKD1_k127_216321_9 Ami_2 - - - 0.0000000000004605 83.0
HKD1_k127_2234484_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 8.197e-321 1002.0
HKD1_k127_2234484_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.761e-259 826.0
HKD1_k127_2234484_10 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 351.0
HKD1_k127_2234484_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 327.0
HKD1_k127_2234484_12 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 317.0
HKD1_k127_2234484_13 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 286.0
HKD1_k127_2234484_14 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009588 284.0
HKD1_k127_2234484_15 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
HKD1_k127_2234484_16 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
HKD1_k127_2234484_17 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001616 226.0
HKD1_k127_2234484_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000008231 226.0
HKD1_k127_2234484_19 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000008328 175.0
HKD1_k127_2234484_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 586.0
HKD1_k127_2234484_20 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000014 161.0
HKD1_k127_2234484_21 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000005113 154.0
HKD1_k127_2234484_22 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000007978 154.0
HKD1_k127_2234484_23 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000000004584 131.0
HKD1_k127_2234484_24 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000006914 133.0
HKD1_k127_2234484_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000002477 115.0
HKD1_k127_2234484_26 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000002928 128.0
HKD1_k127_2234484_27 Lipopolysaccharide-assembly - - - 0.00000000000000000000004338 106.0
HKD1_k127_2234484_28 Ribosomal L32p protein family K02911 - - 0.000000000000000000006924 93.0
HKD1_k127_2234484_29 Ribosomal protein S20 K02968 - - 0.000000000002695 69.0
HKD1_k127_2234484_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 531.0
HKD1_k127_2234484_30 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.000000000005878 75.0
HKD1_k127_2234484_31 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000137 76.0
HKD1_k127_2234484_32 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000007026 70.0
HKD1_k127_2234484_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 466.0
HKD1_k127_2234484_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 473.0
HKD1_k127_2234484_6 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 430.0
HKD1_k127_2234484_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 416.0
HKD1_k127_2234484_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 419.0
HKD1_k127_2234484_9 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
HKD1_k127_2254625_0 Sodium:solute symporter family - - - 8.579e-300 930.0
HKD1_k127_2254625_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.757e-298 925.0
HKD1_k127_2254625_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000001868 102.0
HKD1_k127_2254625_11 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000004162 96.0
HKD1_k127_2254625_13 Tetratricopeptide TPR_2 repeat protein - - - 0.00000001015 66.0
HKD1_k127_2254625_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.323e-248 786.0
HKD1_k127_2254625_3 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 370.0
HKD1_k127_2254625_4 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002132 257.0
HKD1_k127_2254625_5 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000009205 223.0
HKD1_k127_2254625_6 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000002277 172.0
HKD1_k127_2254625_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000003043 143.0
HKD1_k127_2254625_8 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000003607 112.0
HKD1_k127_2254625_9 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000289 108.0
HKD1_k127_2258130_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.205e-283 885.0
HKD1_k127_2258130_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 526.0
HKD1_k127_2258130_10 membrane organization - - - 0.00001964 57.0
HKD1_k127_2258130_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 309.0
HKD1_k127_2258130_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004788 262.0
HKD1_k127_2258130_4 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000001327 179.0
HKD1_k127_2258130_5 G/U mismatch-specific uracil-DNA glycosylase activity K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.0000000000000000000000000000000000000000000002909 175.0
HKD1_k127_2258130_6 EVE domain - - - 0.00000000000000000000000000000000000000000001187 167.0
HKD1_k127_2258130_7 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.000000000000000000005587 103.0
HKD1_k127_2258130_8 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000009571 67.0
HKD1_k127_2258130_9 Histidine kinase - - - 0.0000000104 65.0
HKD1_k127_2270902_0 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000001401 206.0
HKD1_k127_2270902_1 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000002838 188.0
HKD1_k127_2270902_2 - - - - 0.0000000000000000000000001651 123.0
HKD1_k127_2270902_3 - - - - 0.000000000000000000000000698 121.0
HKD1_k127_2270902_5 hmm pf04305 - - - 0.00001868 49.0
HKD1_k127_2274965_0 transmembrane transporter activity K03296 - - 3.337e-255 822.0
HKD1_k127_2274965_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 593.0
HKD1_k127_2274965_10 23S rRNA-intervening sequence protein - - - 0.00000000000001668 88.0
HKD1_k127_2274965_11 Outer membrane efflux protein - - - 0.00000003878 65.0
HKD1_k127_2274965_2 Magnesium chelatase, subunit ChlI K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 469.0
HKD1_k127_2274965_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 432.0
HKD1_k127_2274965_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 389.0
HKD1_k127_2274965_5 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 297.0
HKD1_k127_2274965_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
HKD1_k127_2274965_7 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000007941 196.0
HKD1_k127_2274965_8 Adenylate cyclase - - - 0.000000000000000000001093 109.0
HKD1_k127_2274965_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.000000000000000000001165 109.0
HKD1_k127_2289192_0 Tetratricopeptide repeats K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 431.0
HKD1_k127_2289192_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001337 237.0
HKD1_k127_2289192_2 lactoylglutathione lyase activity - - - 0.0002559 44.0
HKD1_k127_2289192_3 Cupin 2, conserved barrel domain protein - - - 0.0006055 49.0
HKD1_k127_2329992_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 513.0
HKD1_k127_2329992_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 357.0
HKD1_k127_2340212_0 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 1.468e-226 715.0
HKD1_k127_2340212_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
HKD1_k127_2340212_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000003879 77.0
HKD1_k127_2340212_4 PFAM Class II aldolase adducin K03077 - 5.1.3.4 0.00000000009463 70.0
HKD1_k127_2350501_0 TIGRFAM YD repeat protein - - - 0.000000000000000000000000000000000000000000000000000000001108 230.0
HKD1_k127_2350501_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000004406 162.0
HKD1_k127_2364893_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1814.0
HKD1_k127_2364893_1 PLD-like domain - - - 1.888e-224 711.0
HKD1_k127_2364893_2 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000001416 155.0
HKD1_k127_2364893_3 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000388 125.0
HKD1_k127_2364893_5 Domain of unknown function (DUF4115) - - - 0.0002029 53.0
HKD1_k127_2453797_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1268.0
HKD1_k127_2453797_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 4.967e-317 983.0
HKD1_k127_2453797_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 390.0
HKD1_k127_2453797_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 342.0
HKD1_k127_2453797_12 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
HKD1_k127_2453797_13 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 299.0
HKD1_k127_2453797_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004675 279.0
HKD1_k127_2453797_15 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000133 278.0
HKD1_k127_2453797_16 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
HKD1_k127_2453797_17 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
HKD1_k127_2453797_18 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000155 227.0
HKD1_k127_2453797_19 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000001408 216.0
HKD1_k127_2453797_2 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 5.113e-263 818.0
HKD1_k127_2453797_20 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000007702 216.0
HKD1_k127_2453797_21 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001175 201.0
HKD1_k127_2453797_22 - - - - 0.0000000000000000000000000000000000000000000000000000003365 206.0
HKD1_k127_2453797_23 PFAM Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000003116 203.0
HKD1_k127_2453797_24 Dna alkylation repair - - - 0.00000000000000000000000000000000000000883 158.0
HKD1_k127_2453797_25 Methyltransferase domain - - - 0.0000000000000000000000000000000000006435 153.0
HKD1_k127_2453797_26 Chlorophyll synthase, ChlG K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000003977 122.0
HKD1_k127_2453797_27 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000004379 120.0
HKD1_k127_2453797_28 Tetratricopeptide repeat - - - 0.000000000000000007642 95.0
HKD1_k127_2453797_29 phytol kinase 2, chloroplastic K15892 GO:0000003,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006714,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0007275,GO:0008150,GO:0008152,GO:0009719,GO:0009725,GO:0009737,GO:0009791,GO:0009908,GO:0009987,GO:0010033,GO:0016093,GO:0016301,GO:0016310,GO:0016487,GO:0016740,GO:0016772,GO:0016773,GO:0016999,GO:0017144,GO:0022414,GO:0032501,GO:0032502,GO:0033993,GO:0034308,GO:0042221,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0052668,GO:0052669,GO:0052670,GO:0052671,GO:0052673,GO:0061458,GO:0071704,GO:0090567,GO:0097305,GO:0099402,GO:1901615,GO:1901700 2.7.1.216 0.000000001745 70.0
HKD1_k127_2453797_3 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 617.0
HKD1_k127_2453797_30 DivIVA protein K04074 - - 0.00000007365 56.0
HKD1_k127_2453797_31 PBS lyase HEAT-like repeat - - - 0.000111 54.0
HKD1_k127_2453797_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 582.0
HKD1_k127_2453797_5 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 567.0
HKD1_k127_2453797_6 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 543.0
HKD1_k127_2453797_7 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
HKD1_k127_2453797_8 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 441.0
HKD1_k127_2453797_9 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 393.0
HKD1_k127_248177_0 Protein of unknown function (DUF1343) - - - 3.828e-246 787.0
HKD1_k127_248177_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 351.0
HKD1_k127_248177_10 Tetratricopeptide repeat - - - 0.00000000000000000000001833 105.0
HKD1_k127_248177_11 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000002981 84.0
HKD1_k127_248177_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 331.0
HKD1_k127_248177_3 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 308.0
HKD1_k127_248177_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
HKD1_k127_248177_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000001765 254.0
HKD1_k127_248177_6 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000009255 212.0
HKD1_k127_248177_7 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000003089 158.0
HKD1_k127_248177_8 Diguanylate cyclase - - - 0.00000000000000000000000000005081 131.0
HKD1_k127_248177_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000002696 123.0
HKD1_k127_2521132_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000001225 62.0
HKD1_k127_2527186_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 497.0
HKD1_k127_2527186_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
HKD1_k127_2527186_2 Protein of unknown function (DUF2905) - - - 0.00000000000001251 84.0
HKD1_k127_2527186_3 Belongs to the universal stress protein A family - - - 0.000000000000255 71.0
HKD1_k127_2527186_4 Phosphoesterase K07095 - - 0.000000000004222 74.0
HKD1_k127_254255_0 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 620.0
HKD1_k127_254255_1 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 589.0
HKD1_k127_254255_10 SNARE associated Golgi protein - - - 0.00001498 54.0
HKD1_k127_254255_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 405.0
HKD1_k127_254255_3 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 356.0
HKD1_k127_254255_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 342.0
HKD1_k127_254255_5 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 321.0
HKD1_k127_254255_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000006548 180.0
HKD1_k127_254255_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000002842 159.0
HKD1_k127_254255_8 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000316 166.0
HKD1_k127_254255_9 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000002274 107.0
HKD1_k127_2570406_0 Pfam L-fucose isomerase, C-terminal domain - - - 1.563e-214 677.0
HKD1_k127_2570406_1 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 2.969e-196 629.0
HKD1_k127_2570406_2 PFAM glycosyl transferase family 51 K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 425.0
HKD1_k127_2570406_3 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
HKD1_k127_2570406_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000001859 259.0
HKD1_k127_2570406_5 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000008135 221.0
HKD1_k127_2570406_6 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001994 192.0
HKD1_k127_2570406_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000001966 149.0
HKD1_k127_2570406_8 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.000000000000000000000003659 107.0
HKD1_k127_2576553_0 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 340.0
HKD1_k127_2576553_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000002917 186.0
HKD1_k127_2576553_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000001294 88.0
HKD1_k127_2576553_3 AI-2E family transporter - - - 0.00000000001345 69.0
HKD1_k127_2605227_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 582.0
HKD1_k127_2605227_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 351.0
HKD1_k127_2605227_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000001119 205.0
HKD1_k127_2605227_3 TatD related DNase K03424 - - 0.0007647 44.0
HKD1_k127_2650104_0 Tricorn protease homolog K08676 - - 1.418e-290 914.0
HKD1_k127_2650104_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 578.0
HKD1_k127_2650104_2 aspartic-type endopeptidase activity K06985 - - 0.000000000000000000000000000000000000000000000000000000000002331 228.0
HKD1_k127_2650104_3 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000007531 150.0
HKD1_k127_2650104_4 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000001072 124.0
HKD1_k127_2650104_5 von Willebrand factor, type A K07114 - - 0.0000000000000000000000002858 118.0
HKD1_k127_2722362_0 PFAM Glucuronate isomerase K01812 - 5.3.1.12 2.314e-207 654.0
HKD1_k127_2722362_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 9.164e-194 615.0
HKD1_k127_2722362_10 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
HKD1_k127_2722362_11 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 359.0
HKD1_k127_2722362_12 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
HKD1_k127_2722362_13 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HKD1_k127_2722362_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
HKD1_k127_2722362_15 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000001064 227.0
HKD1_k127_2722362_16 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000003424 203.0
HKD1_k127_2722362_17 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K04567,K10716 - 6.1.1.6 0.0000000000000000000000000004979 120.0
HKD1_k127_2722362_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 591.0
HKD1_k127_2722362_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 612.0
HKD1_k127_2722362_4 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 576.0
HKD1_k127_2722362_5 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 501.0
HKD1_k127_2722362_6 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 466.0
HKD1_k127_2722362_7 Glycosyl hydrolases family 28 K01184 - 3.2.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
HKD1_k127_2722362_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 426.0
HKD1_k127_2722362_9 Pfam pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 370.0
HKD1_k127_2876305_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 426.0
HKD1_k127_2876305_1 PFAM EAL domain, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 376.0
HKD1_k127_2961227_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 624.0
HKD1_k127_2961227_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 593.0
HKD1_k127_2961227_10 repeat-containing protein - - - 0.000000004289 63.0
HKD1_k127_2961227_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000006053 55.0
HKD1_k127_2961227_12 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0001799 49.0
HKD1_k127_2961227_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 405.0
HKD1_k127_2961227_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 368.0
HKD1_k127_2961227_4 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000004099 230.0
HKD1_k127_2961227_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000007545 174.0
HKD1_k127_2961227_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000001188 174.0
HKD1_k127_2961227_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000005817 131.0
HKD1_k127_2961227_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000002217 111.0
HKD1_k127_2961227_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000009875 111.0
HKD1_k127_300383_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1075.0
HKD1_k127_300383_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.37e-270 850.0
HKD1_k127_300383_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000003501 89.0
HKD1_k127_300383_11 Cupredoxin-like domain K00376 - 1.7.2.4 0.0000000007278 64.0
HKD1_k127_300383_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 607.0
HKD1_k127_300383_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 504.0
HKD1_k127_300383_4 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003016 291.0
HKD1_k127_300383_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000003251 230.0
HKD1_k127_300383_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000003447 224.0
HKD1_k127_300383_7 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000002646 172.0
HKD1_k127_300383_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001248 141.0
HKD1_k127_300383_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000296 134.0
HKD1_k127_3024087_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 1.833e-244 771.0
HKD1_k127_3024087_1 Predicted membrane protein (DUF2339) - - - 1.17e-240 789.0
HKD1_k127_3024087_10 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 341.0
HKD1_k127_3024087_11 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003065 285.0
HKD1_k127_3024087_12 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002609 254.0
HKD1_k127_3024087_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000004685 202.0
HKD1_k127_3024087_14 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000005772 206.0
HKD1_k127_3024087_15 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000001124 202.0
HKD1_k127_3024087_16 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.00000000000000000000000000000000000000000000000005447 184.0
HKD1_k127_3024087_17 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000208 171.0
HKD1_k127_3024087_18 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000006102 155.0
HKD1_k127_3024087_19 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000004447 140.0
HKD1_k127_3024087_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 559.0
HKD1_k127_3024087_20 Protein kinase domain - - - 0.00000000000000000000000000000000257 140.0
HKD1_k127_3024087_21 Ferredoxin - - - 0.00000000000000000000000000000513 132.0
HKD1_k127_3024087_22 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000008147 124.0
HKD1_k127_3024087_23 DoxX-like family - - - 0.00000000000000000000004446 102.0
HKD1_k127_3024087_24 response regulator, receiver - - - 0.0000000000000000001131 101.0
HKD1_k127_3024087_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001252 69.0
HKD1_k127_3024087_26 helix_turn_helix, Lux Regulon - - - 0.0000000000628 68.0
HKD1_k127_3024087_27 Protein kinase domain - - - 0.0000000006782 65.0
HKD1_k127_3024087_28 Involved in the tonB-independent uptake of proteins - - - 0.000000004148 69.0
HKD1_k127_3024087_29 Protein kinase domain - - - 0.000003105 54.0
HKD1_k127_3024087_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 463.0
HKD1_k127_3024087_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 426.0
HKD1_k127_3024087_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 415.0
HKD1_k127_3024087_6 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 395.0
HKD1_k127_3024087_7 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 372.0
HKD1_k127_3024087_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 351.0
HKD1_k127_3024087_9 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 336.0
HKD1_k127_3027830_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 574.0
HKD1_k127_3027830_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
HKD1_k127_3027830_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HKD1_k127_3027830_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000002147 143.0
HKD1_k127_3032532_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 337.0
HKD1_k127_3032532_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 336.0
HKD1_k127_3032532_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000003709 143.0
HKD1_k127_3032532_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000004882 80.0
HKD1_k127_3032532_4 Transcriptional regulator, GntR family - - - 0.00000002186 62.0
HKD1_k127_3035120_0 peptidyl-tyrosine sulfation - - - 3.583e-206 658.0
HKD1_k127_3035120_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000007641 201.0
HKD1_k127_3035120_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000874 79.0
HKD1_k127_3035120_3 ASPIC and UnbV - - - 0.00000189 50.0
HKD1_k127_3054221_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1373.0
HKD1_k127_3054221_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 554.0
HKD1_k127_3054221_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 349.0
HKD1_k127_3054221_3 amine dehydrogenase activity K09815 - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
HKD1_k127_3069458_0 MacB-like periplasmic core domain - - - 1.217e-228 735.0
HKD1_k127_3069458_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000018 232.0
HKD1_k127_3069458_2 - - - - 0.00000000000000000000000000000000000000000000002277 172.0
HKD1_k127_3069458_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000104 158.0
HKD1_k127_3069458_4 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000008907 148.0
HKD1_k127_3069458_5 EthD domain - - - 0.0000000000000000000000000003794 118.0
HKD1_k127_3069458_7 - - - - 0.0000000000000001366 85.0
HKD1_k127_3069458_8 PFAM CAAX amino terminal protease family - - - 0.000000000000000368 87.0
HKD1_k127_3084609_0 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 378.0
HKD1_k127_3084609_1 Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000996 273.0
HKD1_k127_3084609_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
HKD1_k127_3084609_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000003983 179.0
HKD1_k127_3084609_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000001647 134.0
HKD1_k127_3084609_5 drug resistance transporter K07552 - - 0.000000000000000000000000000001865 128.0
HKD1_k127_3092514_0 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 525.0
HKD1_k127_3092514_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
HKD1_k127_3092514_10 SnoaL-like domain - - - 0.0000001645 59.0
HKD1_k127_3092514_11 - - - - 0.0000002808 60.0
HKD1_k127_3092514_12 - - - - 0.0006272 49.0
HKD1_k127_3092514_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 440.0
HKD1_k127_3092514_3 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 338.0
HKD1_k127_3092514_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000003747 202.0
HKD1_k127_3092514_5 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000001317 188.0
HKD1_k127_3092514_7 Protein of unknown function (DUF2892) - - - 0.00000000000000001518 83.0
HKD1_k127_3092514_8 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000005471 70.0
HKD1_k127_3092514_9 Protein of unknown function (DUF2959) - - - 0.0000001464 61.0
HKD1_k127_3092967_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 370.0
HKD1_k127_3118152_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 333.0
HKD1_k127_3118152_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 298.0
HKD1_k127_3118152_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004313 239.0
HKD1_k127_3118152_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000003456 209.0
HKD1_k127_3119850_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 426.0
HKD1_k127_3119850_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 371.0
HKD1_k127_3119850_2 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000009437 253.0
HKD1_k127_3119850_4 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000009072 227.0
HKD1_k127_3123683_0 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 1.343e-261 846.0
HKD1_k127_3123683_1 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 607.0
HKD1_k127_3123683_10 histone H2A K63-linked ubiquitination K02283 - - 0.0000000000000000000000000000000008396 140.0
HKD1_k127_3123683_11 PFAM Transcriptional - - - 0.00000000000000007996 91.0
HKD1_k127_3123683_12 AlkA N-terminal domain K01247,K13529 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000000001135 68.0
HKD1_k127_3123683_13 Pectinesterase - - - 0.000006327 51.0
HKD1_k127_3123683_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 548.0
HKD1_k127_3123683_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 510.0
HKD1_k127_3123683_4 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 413.0
HKD1_k127_3123683_5 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 406.0
HKD1_k127_3123683_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 352.0
HKD1_k127_3123683_7 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 340.0
HKD1_k127_3123683_8 histone H2A K63-linked ubiquitination K01768,K03220,K10914 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000002407 202.0
HKD1_k127_3123683_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000163 163.0
HKD1_k127_3131016_1 CarboxypepD_reg-like domain - - - 0.0000002755 59.0
HKD1_k127_3132066_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 572.0
HKD1_k127_3132066_1 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000000000000000000000000001201 124.0
HKD1_k127_3136011_0 Multicopper oxidase K22348 - 1.16.3.3 9.171e-238 747.0
HKD1_k127_3136011_1 AcrB/AcrD/AcrF family - - - 8.157e-200 640.0
HKD1_k127_3136011_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 341.0
HKD1_k127_3136011_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000001484 196.0
HKD1_k127_3136011_4 Acid phosphatase homologues - - - 0.0000000000000000000008368 106.0
HKD1_k127_3156764_0 - - - - 1.651e-240 754.0
HKD1_k127_3156764_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000000000000000004105 217.0
HKD1_k127_3156764_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000002445 163.0
HKD1_k127_3156764_3 methyltransferase activity - - - 0.0000000000000000000000000000000000000004018 160.0
HKD1_k127_3156764_4 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000009572 133.0
HKD1_k127_3156764_5 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0007574 51.0
HKD1_k127_3161017_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.525e-257 806.0
HKD1_k127_3161017_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
HKD1_k127_3161017_2 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 526.0
HKD1_k127_3161017_3 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 451.0
HKD1_k127_3161017_4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001351 275.0
HKD1_k127_3174401_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 542.0
HKD1_k127_3174401_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 507.0
HKD1_k127_3174401_10 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 332.0
HKD1_k127_3174401_11 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 295.0
HKD1_k127_3174401_12 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 285.0
HKD1_k127_3174401_13 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001224 291.0
HKD1_k127_3174401_14 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001826 280.0
HKD1_k127_3174401_15 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
HKD1_k127_3174401_16 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005258 286.0
HKD1_k127_3174401_17 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000597 264.0
HKD1_k127_3174401_18 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003116 262.0
HKD1_k127_3174401_19 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004255 264.0
HKD1_k127_3174401_2 phosphopantetheine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 414.0
HKD1_k127_3174401_20 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 260.0
HKD1_k127_3174401_21 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000004491 223.0
HKD1_k127_3174401_22 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000009347 213.0
HKD1_k127_3174401_23 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000003579 217.0
HKD1_k127_3174401_24 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000000193 199.0
HKD1_k127_3174401_25 Chemotaxis protein CheR K00575,K13486 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000006368 196.0
HKD1_k127_3174401_26 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000001267 202.0
HKD1_k127_3174401_28 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000006441 193.0
HKD1_k127_3174401_29 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000002098 186.0
HKD1_k127_3174401_3 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 400.0
HKD1_k127_3174401_30 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000004588 184.0
HKD1_k127_3174401_31 Cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000131 180.0
HKD1_k127_3174401_32 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000001762 171.0
HKD1_k127_3174401_33 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000004932 174.0
HKD1_k127_3174401_34 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000001646 135.0
HKD1_k127_3174401_35 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000096 141.0
HKD1_k127_3174401_36 COG0489 ATPases involved in chromosome partitioning K00903 - 2.7.10.2 0.0000000000000000000000000000007707 132.0
HKD1_k127_3174401_37 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000001229 95.0
HKD1_k127_3174401_38 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.00000000000000006288 95.0
HKD1_k127_3174401_39 O-antigen ligase like membrane protein - - - 0.00000000000000009979 93.0
HKD1_k127_3174401_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 387.0
HKD1_k127_3174401_40 response regulator receiver K13599 - - 0.0000000000000007121 82.0
HKD1_k127_3174401_41 VanZ like family - - - 0.0000000000003238 82.0
HKD1_k127_3174401_42 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000009037 73.0
HKD1_k127_3174401_43 Methyltransferase domain - - - 0.0000000000009878 78.0
HKD1_k127_3174401_44 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000001611 61.0
HKD1_k127_3174401_45 Fibronectin type 3 domain - - - 0.00000000333 70.0
HKD1_k127_3174401_46 VanZ like family - - - 0.0000008402 62.0
HKD1_k127_3174401_47 Phosphopantetheine attachment site K02078 - - 0.000004037 52.0
HKD1_k127_3174401_48 DUF218 domain - - - 0.00001588 55.0
HKD1_k127_3174401_49 asparagine synthase - - - 0.00003489 57.0
HKD1_k127_3174401_5 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 391.0
HKD1_k127_3174401_50 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000514 56.0
HKD1_k127_3174401_51 Beta-L-arabinofuranosidase, GH127 - - - 0.00006285 51.0
HKD1_k127_3174401_52 TonB dependent receptor - - - 0.0006229 51.0
HKD1_k127_3174401_6 Phosphoserine phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 382.0
HKD1_k127_3174401_7 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 358.0
HKD1_k127_3174401_8 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 353.0
HKD1_k127_3174401_9 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
HKD1_k127_3174813_0 FAD linked oxidases, C-terminal domain K06911 - - 0.0 1212.0
HKD1_k127_3174813_1 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1091.0
HKD1_k127_3174813_10 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 602.0
HKD1_k127_3174813_11 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 565.0
HKD1_k127_3174813_12 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 552.0
HKD1_k127_3174813_13 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 520.0
HKD1_k127_3174813_14 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 481.0
HKD1_k127_3174813_15 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 463.0
HKD1_k127_3174813_16 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 461.0
HKD1_k127_3174813_17 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
HKD1_k127_3174813_18 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 444.0
HKD1_k127_3174813_19 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 409.0
HKD1_k127_3174813_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.884e-296 922.0
HKD1_k127_3174813_20 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 407.0
HKD1_k127_3174813_21 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HKD1_k127_3174813_22 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 376.0
HKD1_k127_3174813_23 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
HKD1_k127_3174813_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 373.0
HKD1_k127_3174813_25 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HKD1_k127_3174813_26 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 312.0
HKD1_k127_3174813_27 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000451 293.0
HKD1_k127_3174813_28 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
HKD1_k127_3174813_29 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005488 261.0
HKD1_k127_3174813_3 TIGRFAM glycogen debranching enzyme - - - 2.496e-279 874.0
HKD1_k127_3174813_30 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001289 255.0
HKD1_k127_3174813_31 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008084 252.0
HKD1_k127_3174813_32 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000002237 243.0
HKD1_k127_3174813_33 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000003334 237.0
HKD1_k127_3174813_34 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000304 220.0
HKD1_k127_3174813_35 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000001356 224.0
HKD1_k127_3174813_36 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000001162 219.0
HKD1_k127_3174813_37 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000001172 212.0
HKD1_k127_3174813_38 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000001963 208.0
HKD1_k127_3174813_39 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000008505 215.0
HKD1_k127_3174813_4 WD40-like Beta Propeller Repeat - - - 3.005e-239 776.0
HKD1_k127_3174813_40 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000002089 207.0
HKD1_k127_3174813_41 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000001091 175.0
HKD1_k127_3174813_42 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000005958 173.0
HKD1_k127_3174813_43 Membrane - - - 0.0000000000000000000000000000000000000000002205 174.0
HKD1_k127_3174813_44 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000645 162.0
HKD1_k127_3174813_45 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000004704 162.0
HKD1_k127_3174813_46 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000006383 166.0
HKD1_k127_3174813_47 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000007632 156.0
HKD1_k127_3174813_48 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000002896 134.0
HKD1_k127_3174813_49 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000002916 138.0
HKD1_k127_3174813_5 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.033e-231 733.0
HKD1_k127_3174813_50 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000004016 131.0
HKD1_k127_3174813_51 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000597 121.0
HKD1_k127_3174813_53 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000006626 115.0
HKD1_k127_3174813_54 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000002392 103.0
HKD1_k127_3174813_55 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000001151 100.0
HKD1_k127_3174813_56 ankyrin repeats - - - 0.00001257 56.0
HKD1_k127_3174813_57 YtxH-like protein - - - 0.00002735 50.0
HKD1_k127_3174813_58 Patatin-like phospholipase K07001 - - 0.0001016 55.0
HKD1_k127_3174813_59 Tetratricopeptide repeat - - - 0.0001791 53.0
HKD1_k127_3174813_6 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.233e-230 723.0
HKD1_k127_3174813_7 Beta-L-arabinofuranosidase, GH127 K09955 - - 5.839e-222 707.0
HKD1_k127_3174813_8 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 1.308e-207 661.0
HKD1_k127_3174813_9 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.54e-201 636.0
HKD1_k127_3181596_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 399.0
HKD1_k127_3181596_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000002989 101.0
HKD1_k127_3181596_2 Phosphoesterase family - - - 0.00000000000000000001061 96.0
HKD1_k127_3181596_3 - - - - 0.0001282 51.0
HKD1_k127_3184272_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 577.0
HKD1_k127_3184272_1 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 526.0
HKD1_k127_3184272_10 - - - - 0.0000000000000000000000000000004402 124.0
HKD1_k127_3184272_11 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000002105 117.0
HKD1_k127_3184272_13 Enoyl-(Acyl carrier protein) reductase K00059,K19550 - 1.1.1.100 0.000000003353 60.0
HKD1_k127_3184272_14 Membrane - - - 0.000024 55.0
HKD1_k127_3184272_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 523.0
HKD1_k127_3184272_3 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 371.0
HKD1_k127_3184272_4 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
HKD1_k127_3184272_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 295.0
HKD1_k127_3184272_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 251.0
HKD1_k127_3184272_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000002577 217.0
HKD1_k127_3184272_8 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000009599 209.0
HKD1_k127_3184272_9 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000001319 168.0
HKD1_k127_3191317_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 612.0
HKD1_k127_3191317_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 497.0
HKD1_k127_3191317_10 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000003929 131.0
HKD1_k127_3191317_11 - - - - 0.000000005215 66.0
HKD1_k127_3191317_12 Class III cytochrome C family - - - 0.00000004907 63.0
HKD1_k127_3191317_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 447.0
HKD1_k127_3191317_3 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 443.0
HKD1_k127_3191317_4 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
HKD1_k127_3191317_5 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 313.0
HKD1_k127_3191317_6 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 312.0
HKD1_k127_3191317_7 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
HKD1_k127_3191317_8 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
HKD1_k127_3191317_9 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000001781 209.0
HKD1_k127_3195583_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 3.262e-293 910.0
HKD1_k127_3195583_1 Formate dehydrogenase N, transmembrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 458.0
HKD1_k127_3227659_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001194 288.0
HKD1_k127_3227659_1 PFAM peptidase S49 K04773 - - 0.000003302 53.0
HKD1_k127_3229251_0 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 500.0
HKD1_k127_3229251_1 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 371.0
HKD1_k127_3229251_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009229 241.0
HKD1_k127_324440_0 Fibronectin type III-like domain K05349 - 3.2.1.21 2.778e-199 635.0
HKD1_k127_3246812_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 457.0
HKD1_k127_3246812_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 381.0
HKD1_k127_3246812_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 355.0
HKD1_k127_3246812_3 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004268 254.0
HKD1_k127_3246812_4 Peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
HKD1_k127_3246812_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000003398 204.0
HKD1_k127_3246812_6 Lipase (class 3) K01046 - 3.1.1.3 0.00000000000000000000000000000000000000004904 164.0
HKD1_k127_3290199_0 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000001233 111.0
HKD1_k127_3292716_0 Amino acid permease - - - 2.751e-248 788.0
HKD1_k127_3292716_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.426e-233 730.0
HKD1_k127_3292716_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 439.0
HKD1_k127_3292716_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
HKD1_k127_3292716_4 cystathionine K01760 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 0.0000000002753 61.0
HKD1_k127_3315382_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1353.0
HKD1_k127_3315382_1 cellulose binding - - - 0.0 1257.0
HKD1_k127_3315382_10 peptidase K01415,K07386 - 3.4.24.71 1.901e-250 792.0
HKD1_k127_3315382_100 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000006611 106.0
HKD1_k127_3315382_101 Phosphotransferase System K11189 - - 0.00000000000000000001689 95.0
HKD1_k127_3315382_102 membrane - - - 0.00000000000000000021 97.0
HKD1_k127_3315382_103 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.000000000000000001668 98.0
HKD1_k127_3315382_104 GntR family transcriptional regulator K07979 - - 0.000000000000000002551 89.0
HKD1_k127_3315382_105 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000005583 89.0
HKD1_k127_3315382_106 lipopolysaccharide transport K09774 - - 0.000000000000000005845 99.0
HKD1_k127_3315382_107 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000005607 91.0
HKD1_k127_3315382_108 DoxX-like family - - - 0.00000000000000006911 84.0
HKD1_k127_3315382_109 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000009652 72.0
HKD1_k127_3315382_11 Peptidase S46 - - - 3.494e-226 723.0
HKD1_k127_3315382_110 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000002494 76.0
HKD1_k127_3315382_111 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000062 76.0
HKD1_k127_3315382_112 - - - - 0.000000001085 68.0
HKD1_k127_3315382_113 Protein of unknown function (DUF465) - - - 0.000000002365 61.0
HKD1_k127_3315382_114 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000002916 68.0
HKD1_k127_3315382_115 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000001883 65.0
HKD1_k127_3315382_117 methyltransferase activity - - - 0.000004138 57.0
HKD1_k127_3315382_118 STAS domain - - - 0.000005543 54.0
HKD1_k127_3315382_119 - - - - 0.00001705 54.0
HKD1_k127_3315382_12 Amidase K01426 - 3.5.1.4 3.909e-218 692.0
HKD1_k127_3315382_120 TonB C terminal K03832 - - 0.00003438 54.0
HKD1_k127_3315382_121 Nitrate reductase delta subunit - - - 0.00004623 53.0
HKD1_k127_3315382_122 - - - - 0.0002145 49.0
HKD1_k127_3315382_13 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.623e-204 646.0
HKD1_k127_3315382_14 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 1.521e-195 620.0
HKD1_k127_3315382_15 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 625.0
HKD1_k127_3315382_16 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 602.0
HKD1_k127_3315382_17 sigma factor activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 578.0
HKD1_k127_3315382_18 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 571.0
HKD1_k127_3315382_19 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 567.0
HKD1_k127_3315382_2 Tricorn protease homolog - - - 0.0 1246.0
HKD1_k127_3315382_20 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 527.0
HKD1_k127_3315382_21 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 512.0
HKD1_k127_3315382_22 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 468.0
HKD1_k127_3315382_23 Formate dehydrogenase N, transmembrane K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 447.0
HKD1_k127_3315382_24 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 441.0
HKD1_k127_3315382_25 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 433.0
HKD1_k127_3315382_26 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 422.0
HKD1_k127_3315382_27 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 418.0
HKD1_k127_3315382_28 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 411.0
HKD1_k127_3315382_29 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 383.0
HKD1_k127_3315382_3 Dienelactone hydrolase family - - - 0.0 1142.0
HKD1_k127_3315382_30 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 388.0
HKD1_k127_3315382_31 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 394.0
HKD1_k127_3315382_32 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 374.0
HKD1_k127_3315382_33 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 370.0
HKD1_k127_3315382_34 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 359.0
HKD1_k127_3315382_35 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 365.0
HKD1_k127_3315382_36 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 357.0
HKD1_k127_3315382_37 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 362.0
HKD1_k127_3315382_38 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 360.0
HKD1_k127_3315382_39 Common central domain of tyrosinase K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 337.0
HKD1_k127_3315382_4 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1129.0
HKD1_k127_3315382_40 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 327.0
HKD1_k127_3315382_41 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 344.0
HKD1_k127_3315382_42 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 330.0
HKD1_k127_3315382_43 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
HKD1_k127_3315382_44 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 312.0
HKD1_k127_3315382_45 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
HKD1_k127_3315382_46 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 323.0
HKD1_k127_3315382_47 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 318.0
HKD1_k127_3315382_48 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 297.0
HKD1_k127_3315382_49 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 302.0
HKD1_k127_3315382_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1104.0
HKD1_k127_3315382_50 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 292.0
HKD1_k127_3315382_51 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 292.0
HKD1_k127_3315382_52 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 292.0
HKD1_k127_3315382_53 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009587 295.0
HKD1_k127_3315382_54 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007665 284.0
HKD1_k127_3315382_55 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001816 266.0
HKD1_k127_3315382_56 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000007576 264.0
HKD1_k127_3315382_57 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004568 271.0
HKD1_k127_3315382_58 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
HKD1_k127_3315382_59 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000375 253.0
HKD1_k127_3315382_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 0.0 1092.0
HKD1_k127_3315382_60 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001282 231.0
HKD1_k127_3315382_61 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000001657 231.0
HKD1_k127_3315382_62 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
HKD1_k127_3315382_63 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000006314 224.0
HKD1_k127_3315382_64 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
HKD1_k127_3315382_65 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000001283 214.0
HKD1_k127_3315382_66 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000002008 210.0
HKD1_k127_3315382_67 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000002289 207.0
HKD1_k127_3315382_68 BadF/BadG/BcrA/BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000009413 213.0
HKD1_k127_3315382_69 - K07112 - - 0.000000000000000000000000000000000000000000000000000000001925 206.0
HKD1_k127_3315382_7 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.032e-267 848.0
HKD1_k127_3315382_70 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000005393 229.0
HKD1_k127_3315382_71 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000003746 194.0
HKD1_k127_3315382_72 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000002339 197.0
HKD1_k127_3315382_73 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000198 180.0
HKD1_k127_3315382_74 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000001107 168.0
HKD1_k127_3315382_75 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000008467 172.0
HKD1_k127_3315382_76 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000001192 161.0
HKD1_k127_3315382_77 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000004653 161.0
HKD1_k127_3315382_78 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000005616 157.0
HKD1_k127_3315382_79 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.00000000000000000000000000000000000002552 159.0
HKD1_k127_3315382_8 amine dehydrogenase activity - - - 9.407e-263 840.0
HKD1_k127_3315382_80 YCII-related domain - - - 0.00000000000000000000000000000000000003163 153.0
HKD1_k127_3315382_81 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000001154 146.0
HKD1_k127_3315382_82 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000312 142.0
HKD1_k127_3315382_83 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000001635 149.0
HKD1_k127_3315382_84 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000005401 143.0
HKD1_k127_3315382_85 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000003172 136.0
HKD1_k127_3315382_86 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000000000008387 129.0
HKD1_k127_3315382_87 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001772 126.0
HKD1_k127_3315382_89 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000001067 128.0
HKD1_k127_3315382_9 Phospholipase D. Active site motifs. - - - 4.398e-258 824.0
HKD1_k127_3315382_90 - - - - 0.0000000000000000000000000001575 124.0
HKD1_k127_3315382_91 - - - - 0.000000000000000000000000001407 117.0
HKD1_k127_3315382_92 Protease prsW family - - - 0.000000000000000000000000002035 124.0
HKD1_k127_3315382_93 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000001824 116.0
HKD1_k127_3315382_94 Universal bacterial protein YeaZ K14742 - - 0.0000000000000000000000007029 113.0
HKD1_k127_3315382_95 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.0000000000000000000000009274 121.0
HKD1_k127_3315382_96 PHP domain protein - - - 0.000000000000000000000001476 119.0
HKD1_k127_3315382_97 - - - - 0.00000000000000000000007379 109.0
HKD1_k127_3315382_98 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000146 103.0
HKD1_k127_3315382_99 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000001601 100.0
HKD1_k127_3338458_0 cellulose binding - - - 0.0 1293.0
HKD1_k127_3338458_1 Insulinase (Peptidase family M16) K07263 - - 0.0 1184.0
HKD1_k127_3338458_10 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000001301 168.0
HKD1_k127_3338458_11 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000001883 135.0
HKD1_k127_3338458_12 Peptidase M16 K07263 - - 0.0000000000000000000000000000000564 134.0
HKD1_k127_3338458_13 C-terminal domain of alpha-glycerophosphate oxidase - - - 0.00000000000000000000000007406 111.0
HKD1_k127_3338458_14 Phosphoglycerate mutase family - - - 0.000000000000003509 83.0
HKD1_k127_3338458_15 PFAM AsmA family K07289 - - 0.0000000000004779 82.0
HKD1_k127_3338458_16 Transposase IS200 like K07491 - - 0.00007719 51.0
HKD1_k127_3338458_2 Domain of unknown function (DUF5117) - - - 0.0 1121.0
HKD1_k127_3338458_3 efflux transmembrane transporter activity - - - 8.325e-281 906.0
HKD1_k127_3338458_4 aminopeptidase activity K07004 - - 7e-250 789.0
HKD1_k127_3338458_5 protein secretion by the type I secretion system K11085 - - 2.9e-246 776.0
HKD1_k127_3338458_6 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 509.0
HKD1_k127_3338458_7 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 507.0
HKD1_k127_3338458_8 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 491.0
HKD1_k127_3338458_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 293.0
HKD1_k127_3416132_0 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 2.518e-237 757.0
HKD1_k127_3416132_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 465.0
HKD1_k127_3416132_10 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000000000007911 149.0
HKD1_k127_3416132_11 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000002145 151.0
HKD1_k127_3416132_12 - - - - 0.0000000000000000000000000000003274 135.0
HKD1_k127_3416132_13 - - - - 0.0000000000000001852 86.0
HKD1_k127_3416132_14 Bacterial Ig-like domain 2 - - - 0.00000000000000812 85.0
HKD1_k127_3416132_15 - - - - 0.00000000000006136 84.0
HKD1_k127_3416132_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 398.0
HKD1_k127_3416132_3 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 328.0
HKD1_k127_3416132_4 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009056 241.0
HKD1_k127_3416132_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001913 247.0
HKD1_k127_3416132_6 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000002205 210.0
HKD1_k127_3416132_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000001189 220.0
HKD1_k127_3416132_8 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000006491 192.0
HKD1_k127_3416132_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000001178 173.0
HKD1_k127_3453082_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 396.0
HKD1_k127_3453082_1 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000009262 182.0
HKD1_k127_3453082_2 Haem-binding domain - - - 0.00000000000000000000007093 106.0
HKD1_k127_347016_0 Ankyrin repeats (3 copies) - - - 1.388e-201 641.0
HKD1_k127_347016_1 catalase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 508.0
HKD1_k127_347016_10 Peptidase family M54 - - - 0.0000000000000000000000000000000000000000000000000000000000001924 222.0
HKD1_k127_347016_11 - - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
HKD1_k127_347016_12 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000005958 181.0
HKD1_k127_347016_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000008325 171.0
HKD1_k127_347016_14 TIR domain - - - 0.000000000000000000000000000000000008842 155.0
HKD1_k127_347016_15 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000528 122.0
HKD1_k127_347016_16 serine threonine protein kinase - - - 0.0000000000000000000002494 112.0
HKD1_k127_347016_17 - - - - 0.00000000000000000007665 100.0
HKD1_k127_347016_18 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.000001417 62.0
HKD1_k127_347016_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 485.0
HKD1_k127_347016_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 455.0
HKD1_k127_347016_4 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 432.0
HKD1_k127_347016_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 422.0
HKD1_k127_347016_6 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
HKD1_k127_347016_7 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 254.0
HKD1_k127_347016_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
HKD1_k127_347016_9 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002488 230.0
HKD1_k127_3482301_0 cellulose binding - - - 3.759e-271 871.0
HKD1_k127_3482301_1 hydrolase, family 3 K05349 - 3.2.1.21 1.597e-261 826.0
HKD1_k127_3482301_10 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 294.0
HKD1_k127_3482301_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000223 271.0
HKD1_k127_3482301_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000002273 249.0
HKD1_k127_3482301_13 Thermolysin metallopeptidase, alpha-helical domain K01400 GO:0005575,GO:0005576 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000001712 250.0
HKD1_k127_3482301_14 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000003243 217.0
HKD1_k127_3482301_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001434 211.0
HKD1_k127_3482301_16 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000002032 192.0
HKD1_k127_3482301_17 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000001841 193.0
HKD1_k127_3482301_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000003177 169.0
HKD1_k127_3482301_19 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000003903 171.0
HKD1_k127_3482301_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 606.0
HKD1_k127_3482301_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000002605 153.0
HKD1_k127_3482301_21 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000007968 150.0
HKD1_k127_3482301_22 Penicillinase repressor - - - 0.0000000000000000000000000000000002257 135.0
HKD1_k127_3482301_23 Putative adhesin - - - 0.0000000000000000000000000001088 129.0
HKD1_k127_3482301_24 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000001681 83.0
HKD1_k127_3482301_25 - - - - 0.0000000001391 71.0
HKD1_k127_3482301_26 TK COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000002952 59.0
HKD1_k127_3482301_27 FAST kinase - GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.0002758 45.0
HKD1_k127_3482301_28 shape-determining protein MreD K03571 - - 0.0003048 51.0
HKD1_k127_3482301_29 HEAT repeat - - - 0.0009644 52.0
HKD1_k127_3482301_3 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 555.0
HKD1_k127_3482301_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 508.0
HKD1_k127_3482301_5 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 501.0
HKD1_k127_3482301_6 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 494.0
HKD1_k127_3482301_7 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 472.0
HKD1_k127_3482301_8 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 407.0
HKD1_k127_3482301_9 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 307.0
HKD1_k127_3582475_0 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 368.0
HKD1_k127_3582475_1 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000001992 199.0
HKD1_k127_3582475_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000004197 118.0
HKD1_k127_3582475_3 Protein of unknown function (DUF3108) - - - 0.0000004289 61.0
HKD1_k127_3582770_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.727e-242 773.0
HKD1_k127_3582770_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.439e-207 656.0
HKD1_k127_3582770_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 341.0
HKD1_k127_3582770_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 320.0
HKD1_k127_3582770_12 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 318.0
HKD1_k127_3582770_13 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005345 289.0
HKD1_k127_3582770_14 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009782 262.0
HKD1_k127_3582770_15 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000007241 232.0
HKD1_k127_3582770_16 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
HKD1_k127_3582770_17 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
HKD1_k127_3582770_18 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000008421 242.0
HKD1_k127_3582770_19 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000004653 213.0
HKD1_k127_3582770_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.206e-201 645.0
HKD1_k127_3582770_20 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000007301 201.0
HKD1_k127_3582770_21 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000002729 179.0
HKD1_k127_3582770_22 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000001247 176.0
HKD1_k127_3582770_23 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000008143 156.0
HKD1_k127_3582770_24 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000009572 158.0
HKD1_k127_3582770_25 nuclear chromosome segregation - - - 0.000000000000000000000000000000001534 151.0
HKD1_k127_3582770_26 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000001803 132.0
HKD1_k127_3582770_27 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.0000000000000000000000003846 111.0
HKD1_k127_3582770_28 - - - - 0.00000000000000000001583 94.0
HKD1_k127_3582770_29 phosphoesterases, related to the Icc protein - - - 0.00000000000000002848 87.0
HKD1_k127_3582770_3 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 559.0
HKD1_k127_3582770_30 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000001161 66.0
HKD1_k127_3582770_4 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 415.0
HKD1_k127_3582770_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 402.0
HKD1_k127_3582770_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 394.0
HKD1_k127_3582770_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 383.0
HKD1_k127_3582770_8 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 378.0
HKD1_k127_3582770_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 357.0
HKD1_k127_3585794_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 337.0
HKD1_k127_360577_0 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001845 261.0
HKD1_k127_360577_1 Ion channel - - - 0.000000000000000000000000000000000000000000165 164.0
HKD1_k127_360783_0 Zinc carboxypeptidase - - - 0.0 1095.0
HKD1_k127_360783_1 pathogenesis - - - 8.286e-258 858.0
HKD1_k127_360783_10 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 413.0
HKD1_k127_360783_11 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 385.0
HKD1_k127_360783_12 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 381.0
HKD1_k127_360783_13 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 351.0
HKD1_k127_360783_14 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 351.0
HKD1_k127_360783_15 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0071704,GO:1901564 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 343.0
HKD1_k127_360783_16 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 310.0
HKD1_k127_360783_17 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 297.0
HKD1_k127_360783_18 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 296.0
HKD1_k127_360783_19 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004495 271.0
HKD1_k127_360783_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 3.801e-256 805.0
HKD1_k127_360783_20 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001203 257.0
HKD1_k127_360783_21 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000000000000000003911 185.0
HKD1_k127_360783_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000001159 161.0
HKD1_k127_360783_23 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000008455 133.0
HKD1_k127_360783_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000003676 136.0
HKD1_k127_360783_25 von Willebrand factor, type A - - - 0.0000000000000000000000000001026 126.0
HKD1_k127_360783_26 Psort location Cytoplasmic, score 8.96 K07397 - - 0.000000000000000000000001056 108.0
HKD1_k127_360783_27 DNA-sulfur modification-associated - - - 0.00000000000000005511 93.0
HKD1_k127_360783_28 AraC family transcriptional regulator - - - 0.000000002015 68.0
HKD1_k127_360783_29 BON domain K04065 - - 0.00000000289 68.0
HKD1_k127_360783_3 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 6.965e-220 707.0
HKD1_k127_360783_30 - - - - 0.00000008492 63.0
HKD1_k127_360783_31 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0000003943 54.0
HKD1_k127_360783_32 - - - - 0.000008518 51.0
HKD1_k127_360783_33 - - - - 0.00001111 55.0
HKD1_k127_360783_34 - - - - 0.00004647 53.0
HKD1_k127_360783_4 Carbon starvation protein CstA K06200 - - 1.92e-218 693.0
HKD1_k127_360783_5 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 3.313e-211 722.0
HKD1_k127_360783_6 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 606.0
HKD1_k127_360783_7 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 555.0
HKD1_k127_360783_8 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 451.0
HKD1_k127_360783_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 427.0
HKD1_k127_3641256_0 Peptidase family M28 - - - 8.607e-206 654.0
HKD1_k127_3641256_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 554.0
HKD1_k127_3641256_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001747 269.0
HKD1_k127_3641256_3 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000002639 133.0
HKD1_k127_3641256_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000218 95.0
HKD1_k127_3641256_5 Protein of unknown function (DUF1653) - - - 0.0001671 51.0
HKD1_k127_3641256_6 Subtilase family - - - 0.0007951 50.0
HKD1_k127_3669336_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 1.482e-218 700.0
HKD1_k127_3669336_1 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 540.0
HKD1_k127_3669336_10 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.00000000000000000000000000000001941 146.0
HKD1_k127_3669336_11 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000004332 89.0
HKD1_k127_3669336_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000001555 87.0
HKD1_k127_3669336_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.00001895 55.0
HKD1_k127_3669336_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 505.0
HKD1_k127_3669336_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 522.0
HKD1_k127_3669336_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 486.0
HKD1_k127_3669336_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 393.0
HKD1_k127_3669336_6 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 355.0
HKD1_k127_3669336_7 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000005051 237.0
HKD1_k127_3669336_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000003076 226.0
HKD1_k127_3669336_9 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000001443 211.0
HKD1_k127_3681775_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.205e-209 660.0
HKD1_k127_3681775_1 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
HKD1_k127_3681775_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 484.0
HKD1_k127_3681775_3 receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 434.0
HKD1_k127_3906197_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 4.951e-284 893.0
HKD1_k127_3906197_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.515e-266 838.0
HKD1_k127_3906197_10 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000001685 87.0
HKD1_k127_3906197_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.232e-218 696.0
HKD1_k127_3906197_3 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 563.0
HKD1_k127_3906197_4 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 452.0
HKD1_k127_3906197_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000003078 230.0
HKD1_k127_3906197_6 Exonuclease K07502 - - 0.00000000000000000000000000000000000000000000008426 189.0
HKD1_k127_3906197_7 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000004319 152.0
HKD1_k127_3906197_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000003985 138.0
HKD1_k127_3906197_9 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001045 114.0
HKD1_k127_3920631_0 Pfam L-fucose isomerase, C-terminal domain - - - 9.984e-216 683.0
HKD1_k127_3920631_1 PFAM Major facilitator superfamily K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 526.0
HKD1_k127_3920631_10 E-Z type HEAT repeats - - - 0.0000000003161 74.0
HKD1_k127_3920631_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 440.0
HKD1_k127_3920631_3 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 425.0
HKD1_k127_3920631_4 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 357.0
HKD1_k127_3920631_5 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 334.0
HKD1_k127_3920631_6 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 323.0
HKD1_k127_3920631_7 Dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000003098 261.0
HKD1_k127_3920631_8 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002659 229.0
HKD1_k127_3920631_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000009297 82.0
HKD1_k127_3961777_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1136.0
HKD1_k127_3961777_1 nitrite transmembrane transporter activity - - - 0.0 1037.0
HKD1_k127_3961777_10 Heavy-metal resistance - - - 0.000002233 57.0
HKD1_k127_3961777_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 2.592e-215 689.0
HKD1_k127_3961777_3 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 497.0
HKD1_k127_3961777_4 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 461.0
HKD1_k127_3961777_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 287.0
HKD1_k127_3961777_6 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
HKD1_k127_3961777_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000002036 146.0
HKD1_k127_3961777_8 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000001948 123.0
HKD1_k127_39978_1 cellulase activity - - - 0.00006409 54.0
HKD1_k127_39978_2 cellulase activity - - - 0.0001254 50.0
HKD1_k127_4030993_0 MacB-like periplasmic core domain - - - 0.0 1038.0
HKD1_k127_4030993_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 558.0
HKD1_k127_4030993_10 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
HKD1_k127_4030993_11 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000001827 158.0
HKD1_k127_4030993_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000006393 142.0
HKD1_k127_4030993_13 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000004384 121.0
HKD1_k127_4030993_14 - - - - 0.0000000000000001937 85.0
HKD1_k127_4030993_15 Glucose / Sorbosone dehydrogenase - - - 0.0000000000006517 78.0
HKD1_k127_4030993_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 432.0
HKD1_k127_4030993_3 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 331.0
HKD1_k127_4030993_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 278.0
HKD1_k127_4030993_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005407 286.0
HKD1_k127_4030993_6 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001726 276.0
HKD1_k127_4030993_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006095 290.0
HKD1_k127_4030993_8 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000006573 230.0
HKD1_k127_4030993_9 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000001846 226.0
HKD1_k127_4031363_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.652e-206 650.0
HKD1_k127_4031363_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 553.0
HKD1_k127_4031363_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 518.0
HKD1_k127_4031363_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 447.0
HKD1_k127_4031363_4 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 423.0
HKD1_k127_4031363_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 330.0
HKD1_k127_4031363_6 CoA-binding protein K06929 - - 0.00000000000000000000000000000000009286 139.0
HKD1_k127_4031363_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000003761 99.0
HKD1_k127_4031363_8 acyl carrier protein - - - 0.0000000000004532 74.0
HKD1_k127_4032840_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 2.622e-257 814.0
HKD1_k127_4032840_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.761e-245 780.0
HKD1_k127_4032840_10 Extracellular repeat protein, HAF family - - - 0.00000000000000000003721 103.0
HKD1_k127_4032840_11 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000001469 90.0
HKD1_k127_4032840_12 energy transducer activity K02487,K03832,K06596 - - 0.0000000000000005264 84.0
HKD1_k127_4032840_13 - - - - 0.0000008977 53.0
HKD1_k127_4032840_14 Transcriptional regulatory protein, C terminal - - - 0.00007671 46.0
HKD1_k127_4032840_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 519.0
HKD1_k127_4032840_3 PFAM glycoside hydrolase, family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 340.0
HKD1_k127_4032840_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 338.0
HKD1_k127_4032840_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001853 233.0
HKD1_k127_4032840_6 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000001277 211.0
HKD1_k127_4032840_7 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000002248 167.0
HKD1_k127_4032840_8 - - - - 0.000000000000000000000000000003446 125.0
HKD1_k127_4032840_9 Cytochrome c554 and c-prime - - - 0.000000000000000000003336 101.0
HKD1_k127_4037833_0 Succinyl-CoA ligase like flavodoxin domain - - - 1.066e-261 834.0
HKD1_k127_4037833_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 568.0
HKD1_k127_4037833_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000001884 161.0
HKD1_k127_4037833_11 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000005595 160.0
HKD1_k127_4037833_12 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000003541 137.0
HKD1_k127_4037833_13 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.00000000000000000000000000003221 122.0
HKD1_k127_4037833_14 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000008784 105.0
HKD1_k127_4037833_15 NifU-like domain - - - 0.00000000000000006908 83.0
HKD1_k127_4037833_16 negative regulation of growth - - - 0.0000000000005495 71.0
HKD1_k127_4037833_18 - - - - 0.0000004624 60.0
HKD1_k127_4037833_2 COGs COG3387 Glucoamylase and related glycosyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 564.0
HKD1_k127_4037833_3 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 552.0
HKD1_k127_4037833_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 481.0
HKD1_k127_4037833_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 328.0
HKD1_k127_4037833_6 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 296.0
HKD1_k127_4037833_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003112 243.0
HKD1_k127_4037833_8 FAD binding domain K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000000000005326 174.0
HKD1_k127_4037833_9 Universal stress protein family - - - 0.0000000000000000000000000000000000000000005612 161.0
HKD1_k127_4056579_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 564.0
HKD1_k127_4056579_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 473.0
HKD1_k127_4056579_2 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 433.0
HKD1_k127_4056579_3 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 407.0
HKD1_k127_4056579_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 350.0
HKD1_k127_4056579_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 328.0
HKD1_k127_4056579_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
HKD1_k127_4056579_7 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000000007634 136.0
HKD1_k127_4059459_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 594.0
HKD1_k127_4059459_1 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 447.0
HKD1_k127_4059459_10 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 309.0
HKD1_k127_4059459_11 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 290.0
HKD1_k127_4059459_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004631 282.0
HKD1_k127_4059459_13 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001222 286.0
HKD1_k127_4059459_14 CARDB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003858 272.0
HKD1_k127_4059459_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
HKD1_k127_4059459_16 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000005748 235.0
HKD1_k127_4059459_17 - K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000002285 235.0
HKD1_k127_4059459_18 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000005645 207.0
HKD1_k127_4059459_19 peptidase M36 K01417 - - 0.00000000000000000000000000000000000000000000000000000003563 226.0
HKD1_k127_4059459_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 420.0
HKD1_k127_4059459_20 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000000000005544 166.0
HKD1_k127_4059459_21 Sporulation initiation inhibitor K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.00000000000000000000000000000000000002789 161.0
HKD1_k127_4059459_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000001243 89.0
HKD1_k127_4059459_23 DinB superfamily - - - 0.0000000000000002313 85.0
HKD1_k127_4059459_24 Putative Ig domain - - - 0.0000000000000005966 94.0
HKD1_k127_4059459_25 Protein of unknown function, DUF481 K07283 - - 0.00000000007843 74.0
HKD1_k127_4059459_26 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000006138 73.0
HKD1_k127_4059459_27 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000001024 60.0
HKD1_k127_4059459_28 Membrane - - - 0.0000003519 59.0
HKD1_k127_4059459_29 glyoxalase III activity - - - 0.0001524 52.0
HKD1_k127_4059459_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 408.0
HKD1_k127_4059459_30 Response regulator receiver K03413 - - 0.0002385 53.0
HKD1_k127_4059459_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 398.0
HKD1_k127_4059459_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 371.0
HKD1_k127_4059459_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
HKD1_k127_4059459_7 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 355.0
HKD1_k127_4059459_8 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 332.0
HKD1_k127_4059459_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 307.0
HKD1_k127_4067534_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 390.0
HKD1_k127_4067534_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000001453 174.0
HKD1_k127_4067534_2 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.0000000000000000004565 100.0
HKD1_k127_407752_0 Glutaryl-7-ACA acylase K06978 - - 1.605e-316 979.0
HKD1_k127_407752_1 MacB-like periplasmic core domain - - - 1.611e-309 970.0
HKD1_k127_407752_10 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 599.0
HKD1_k127_407752_11 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 535.0
HKD1_k127_407752_12 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 520.0
HKD1_k127_407752_13 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 510.0
HKD1_k127_407752_14 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 501.0
HKD1_k127_407752_15 amidase activity K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 482.0
HKD1_k127_407752_16 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 479.0
HKD1_k127_407752_17 Chase2 domain K01768,K07814 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 442.0
HKD1_k127_407752_18 RND efflux system, outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 422.0
HKD1_k127_407752_19 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 412.0
HKD1_k127_407752_2 Aldehyde dehydrogenase family K00138 - - 2.912e-279 866.0
HKD1_k127_407752_20 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 403.0
HKD1_k127_407752_21 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 395.0
HKD1_k127_407752_22 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 399.0
HKD1_k127_407752_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 399.0
HKD1_k127_407752_25 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 386.0
HKD1_k127_407752_26 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 387.0
HKD1_k127_407752_27 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 368.0
HKD1_k127_407752_28 PFAM Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 376.0
HKD1_k127_407752_29 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 392.0
HKD1_k127_407752_3 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 4.415e-265 842.0
HKD1_k127_407752_30 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 385.0
HKD1_k127_407752_31 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 359.0
HKD1_k127_407752_32 GHMP kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 351.0
HKD1_k127_407752_33 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 337.0
HKD1_k127_407752_34 Nadph-dependent fmn reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 332.0
HKD1_k127_407752_35 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 324.0
HKD1_k127_407752_36 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 317.0
HKD1_k127_407752_37 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 320.0
HKD1_k127_407752_38 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 304.0
HKD1_k127_407752_39 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 296.0
HKD1_k127_407752_4 Sodium:solute symporter family - - - 1.104e-214 683.0
HKD1_k127_407752_40 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
HKD1_k127_407752_41 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
HKD1_k127_407752_42 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
HKD1_k127_407752_43 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002898 278.0
HKD1_k127_407752_44 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009489 265.0
HKD1_k127_407752_45 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
HKD1_k127_407752_46 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003557 258.0
HKD1_k127_407752_47 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001799 248.0
HKD1_k127_407752_48 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003243 235.0
HKD1_k127_407752_49 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000006455 239.0
HKD1_k127_407752_5 Protein tyrosine kinase K12132 - 2.7.11.1 3.158e-209 688.0
HKD1_k127_407752_50 - - - - 0.00000000000000000000000000000000000000000000000000000000000001727 237.0
HKD1_k127_407752_51 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000002122 215.0
HKD1_k127_407752_52 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000002888 211.0
HKD1_k127_407752_53 domain, Protein K15125 - - 0.0000000000000000000000000000000000000000000000000000004328 223.0
HKD1_k127_407752_54 Protein conserved in bacteria K09959 - - 0.0000000000000000000000000000000000000000000000000007672 194.0
HKD1_k127_407752_55 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000109 184.0
HKD1_k127_407752_56 phosphohistidine phosphatase, SixA - - - 0.0000000000000000000000000000000000000000000000001446 193.0
HKD1_k127_407752_57 O-methyltransferase family 3 - - - 0.0000000000000000000000000000000000000000000001744 175.0
HKD1_k127_407752_58 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000001131 177.0
HKD1_k127_407752_59 conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000003369 187.0
HKD1_k127_407752_6 Carbohydrate family 9 binding domain-like - - - 1.474e-207 676.0
HKD1_k127_407752_60 - - - - 0.00000000000000000000000000000000000000000008833 163.0
HKD1_k127_407752_61 - - - - 0.0000000000000000000000000000000000000000008086 168.0
HKD1_k127_407752_62 Peptidase M60-like family - - - 0.000000000000000000000000000000000000000002847 171.0
HKD1_k127_407752_63 TIR domain - - - 0.000000000000000000000000000000000000000004211 172.0
HKD1_k127_407752_64 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001674 163.0
HKD1_k127_407752_66 OmpA family - - - 0.00000000000000000000000000000000000007494 151.0
HKD1_k127_407752_67 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000817 149.0
HKD1_k127_407752_68 methyltransferase - - - 0.000000000000000000000000000000006479 141.0
HKD1_k127_407752_69 GYD domain - - - 0.0000000000000000000000000000003521 124.0
HKD1_k127_407752_7 Peptidase family M28 - - - 4.592e-206 656.0
HKD1_k127_407752_70 FecR protein - - - 0.0000000000000000000000000000007475 127.0
HKD1_k127_407752_71 Protein of unknown function (DUF3788) - - - 0.00000000000000000000000000001558 122.0
HKD1_k127_407752_72 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000005399 118.0
HKD1_k127_407752_73 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000001911 119.0
HKD1_k127_407752_74 Trypsin K04771 - 3.4.21.107 0.00000000000000000000002167 115.0
HKD1_k127_407752_75 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000005265 106.0
HKD1_k127_407752_76 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000003849 91.0
HKD1_k127_407752_77 cytochrome c K00368 - 1.7.2.1 0.000000000000000000579 95.0
HKD1_k127_407752_78 - - - - 0.000000000000000005244 93.0
HKD1_k127_407752_79 multi-organism process K03195 - - 0.00000000000000006576 89.0
HKD1_k127_407752_8 Cystathionine beta-synthase K01697 - 4.2.1.22 1.794e-202 639.0
HKD1_k127_407752_80 STAS domain K04749 - - 0.000000000000001054 81.0
HKD1_k127_407752_81 Protein of unknown function (DUF3309) - - - 0.000000000000007518 74.0
HKD1_k127_407752_82 Surface antigen - - - 0.00000000000005611 84.0
HKD1_k127_407752_83 Heat shock protein DnaJ domain protein - - - 0.000000000000512 79.0
HKD1_k127_407752_84 Tetratricopeptide repeat - - - 0.000000000008312 78.0
HKD1_k127_407752_85 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000002283 72.0
HKD1_k127_407752_86 YceI-like domain - - - 0.000000007817 64.0
HKD1_k127_407752_87 Type VI secretion system VasI, EvfG, VC_A0118 K11909 - - 0.00000003243 65.0
HKD1_k127_407752_88 PFAM Ig domain protein, group 2 domain protein - - - 0.00000009888 64.0
HKD1_k127_407752_89 SnoaL-like polyketide cyclase - - - 0.000003436 55.0
HKD1_k127_407752_9 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 610.0
HKD1_k127_407752_90 Cupredoxin-like domain - - - 0.000008218 53.0
HKD1_k127_407752_91 antisigma factor binding K04749,K20978 - - 0.0000126 52.0
HKD1_k127_407752_92 pyrroloquinoline quinone binding - - - 0.00006766 51.0
HKD1_k127_407752_93 CAAX protease self-immunity - - - 0.0001053 53.0
HKD1_k127_407752_94 Belongs to the sulfur carrier protein TusA family - - - 0.0001731 53.0
HKD1_k127_4099648_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
HKD1_k127_4099648_1 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000004678 152.0
HKD1_k127_4122935_0 Tricorn protease homolog K08676 - - 0.0 1269.0
HKD1_k127_4122935_1 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 0.0 1229.0
HKD1_k127_4122935_10 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 524.0
HKD1_k127_4122935_11 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 521.0
HKD1_k127_4122935_12 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 522.0
HKD1_k127_4122935_13 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 493.0
HKD1_k127_4122935_14 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 490.0
HKD1_k127_4122935_15 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 485.0
HKD1_k127_4122935_16 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 439.0
HKD1_k127_4122935_17 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 378.0
HKD1_k127_4122935_18 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 382.0
HKD1_k127_4122935_19 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 373.0
HKD1_k127_4122935_2 Carboxypeptidase regulatory-like domain - - - 0.0 1221.0
HKD1_k127_4122935_20 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 364.0
HKD1_k127_4122935_21 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 346.0
HKD1_k127_4122935_22 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 329.0
HKD1_k127_4122935_23 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 336.0
HKD1_k127_4122935_24 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 297.0
HKD1_k127_4122935_25 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 321.0
HKD1_k127_4122935_26 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
HKD1_k127_4122935_27 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 289.0
HKD1_k127_4122935_28 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 285.0
HKD1_k127_4122935_29 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
HKD1_k127_4122935_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1155.0
HKD1_k127_4122935_30 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
HKD1_k127_4122935_31 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HKD1_k127_4122935_32 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002345 267.0
HKD1_k127_4122935_33 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000533 246.0
HKD1_k127_4122935_34 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000007517 248.0
HKD1_k127_4122935_35 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000001768 250.0
HKD1_k127_4122935_36 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 240.0
HKD1_k127_4122935_37 DNA recombination-mediator protein A K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002062 252.0
HKD1_k127_4122935_38 Surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000194 261.0
HKD1_k127_4122935_39 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000319 242.0
HKD1_k127_4122935_4 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.503e-250 784.0
HKD1_k127_4122935_40 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000002448 237.0
HKD1_k127_4122935_41 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000003938 244.0
HKD1_k127_4122935_42 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000003734 214.0
HKD1_k127_4122935_43 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000001832 207.0
HKD1_k127_4122935_44 phosphorelay sensor kinase activity K07710,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000003303 211.0
HKD1_k127_4122935_45 PFAM Binding-protein-dependent transport K02033 - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
HKD1_k127_4122935_46 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000001338 201.0
HKD1_k127_4122935_47 - - - - 0.0000000000000000000000000000000000000000000000000008542 190.0
HKD1_k127_4122935_48 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000002837 204.0
HKD1_k127_4122935_49 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000003128 177.0
HKD1_k127_4122935_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.882e-221 714.0
HKD1_k127_4122935_50 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000002135 163.0
HKD1_k127_4122935_51 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000007525 164.0
HKD1_k127_4122935_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000005079 150.0
HKD1_k127_4122935_53 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000001466 144.0
HKD1_k127_4122935_54 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000004846 131.0
HKD1_k127_4122935_55 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000001574 143.0
HKD1_k127_4122935_56 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000007321 128.0
HKD1_k127_4122935_57 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000002694 132.0
HKD1_k127_4122935_58 PFAM NLP P60 protein - - - 0.0000000000000000000000000008502 126.0
HKD1_k127_4122935_59 Protein conserved in bacteria - - - 0.000000000000000000000000001232 117.0
HKD1_k127_4122935_6 C-terminus of AA_permease K03294 - - 1.393e-220 694.0
HKD1_k127_4122935_60 radical SAM domain protein - - - 0.000000000000000000000000276 120.0
HKD1_k127_4122935_61 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000003101 110.0
HKD1_k127_4122935_62 response regulator - - - 0.00000000000000000000003387 106.0
HKD1_k127_4122935_63 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000003403 96.0
HKD1_k127_4122935_65 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000006532 94.0
HKD1_k127_4122935_66 Periplasmic or secreted lipoprotein - - - 0.000000000000000001678 97.0
HKD1_k127_4122935_67 Fibronectin type 3 domain - - - 0.00000000000000001552 96.0
HKD1_k127_4122935_68 Biotin lipoyl attachment - - - 0.0000000000000003474 92.0
HKD1_k127_4122935_69 - - - - 0.0000000000000007277 89.0
HKD1_k127_4122935_7 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.516e-202 638.0
HKD1_k127_4122935_70 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000162 82.0
HKD1_k127_4122935_71 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000004405 83.0
HKD1_k127_4122935_72 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000003878 79.0
HKD1_k127_4122935_73 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000009643 71.0
HKD1_k127_4122935_74 Major Facilitator Superfamily - - - 0.00000000006093 75.0
HKD1_k127_4122935_75 DNA binding domain, excisionase family - - - 0.0000000001753 64.0
HKD1_k127_4122935_76 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000222 69.0
HKD1_k127_4122935_77 - - - - 0.000000001651 66.0
HKD1_k127_4122935_78 Acetyltransferase (GNAT) domain - - - 0.000000008819 65.0
HKD1_k127_4122935_79 TIGRFAM amino acid adenylation domain - - - 0.00000002714 66.0
HKD1_k127_4122935_8 ABC transporter C-terminal domain K06158 - - 1.329e-201 647.0
HKD1_k127_4122935_81 fOG TPR repeat - - - 0.0000003422 58.0
HKD1_k127_4122935_82 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000005911 58.0
HKD1_k127_4122935_84 CAAX protease self-immunity K01266,K07052 - 3.4.11.19 0.0001112 53.0
HKD1_k127_4122935_85 Putative zinc-finger - - - 0.0006577 50.0
HKD1_k127_4122935_86 cytochrome C peroxidase - - - 0.000776 48.0
HKD1_k127_4122935_9 TIGRFAM amidase, hydantoinase carbamoylase K02083,K06016,K18151 - 3.5.1.116,3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 530.0
HKD1_k127_4131114_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 481.0
HKD1_k127_4131114_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
HKD1_k127_4131114_2 SIS domain - - - 0.000000000000000000000000000000000000000000000004379 178.0
HKD1_k127_4131114_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000001224 155.0
HKD1_k127_4131114_4 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000361 143.0
HKD1_k127_4131114_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000004946 139.0
HKD1_k127_4131114_6 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000003588 85.0
HKD1_k127_4140166_0 Radical SAM - - - 0.0 1124.0
HKD1_k127_4140166_1 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 599.0
HKD1_k127_4140166_10 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 283.0
HKD1_k127_4140166_11 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002047 271.0
HKD1_k127_4140166_12 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
HKD1_k127_4140166_13 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000003729 212.0
HKD1_k127_4140166_14 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000004036 192.0
HKD1_k127_4140166_15 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000003512 188.0
HKD1_k127_4140166_16 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000001383 179.0
HKD1_k127_4140166_17 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000001997 181.0
HKD1_k127_4140166_18 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000002433 177.0
HKD1_k127_4140166_19 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000001983 153.0
HKD1_k127_4140166_2 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 509.0
HKD1_k127_4140166_20 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000001608 153.0
HKD1_k127_4140166_21 methyltransferase - - - 0.00000000000000000000000000000158 132.0
HKD1_k127_4140166_22 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000000003161 129.0
HKD1_k127_4140166_23 O-Antigen ligase - - - 0.00000000000000000001455 106.0
HKD1_k127_4140166_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000005808 94.0
HKD1_k127_4140166_26 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000001771 90.0
HKD1_k127_4140166_27 Pregnancy-associated plasma protein-A - - - 0.0000000000006323 83.0
HKD1_k127_4140166_28 Histidine kinase K02484,K07656 - 2.7.13.3 0.00000000001907 73.0
HKD1_k127_4140166_29 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase K09809 - 2.7.8.12 0.0000000001364 73.0
HKD1_k127_4140166_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 451.0
HKD1_k127_4140166_30 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000007928 71.0
HKD1_k127_4140166_31 PLD-like domain - - - 0.00000001413 68.0
HKD1_k127_4140166_32 Phospholipase D family member 6 K16862 GO:0000003,GO:0000578,GO:0003002,GO:0003006,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004620,GO:0004630,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005789,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007028,GO:0007049,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007350,GO:0007351,GO:0007389,GO:0008053,GO:0008081,GO:0008150,GO:0008152,GO:0008358,GO:0008595,GO:0008610,GO:0008654,GO:0009058,GO:0009790,GO:0009798,GO:0009880,GO:0009892,GO:0009948,GO:0009952,GO:0009987,GO:0009994,GO:0010468,GO:0010605,GO:0010629,GO:0010635,GO:0010636,GO:0010638,GO:0010821,GO:0010822,GO:0012505,GO:0016020,GO:0016043,GO:0016070,GO:0016298,GO:0016458,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019222,GO:0019637,GO:0019867,GO:0019953,GO:0021700,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0030154,GO:0030717,GO:0030719,GO:0031047,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0031984,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033043,GO:0034587,GO:0034641,GO:0034660,GO:0035282,GO:0035755,GO:0035770,GO:0036464,GO:0042175,GO:0042578,GO:0042802,GO:0042803,GO:0043046,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044728,GO:0045017,GO:0045495,GO:0046473,GO:0046474,GO:0046483,GO:0046486,GO:0046983,GO:0048232,GO:0048284,GO:0048468,GO:0048469,GO:0048477,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051276,GO:0051321,GO:0051704,GO:0060255,GO:0060293,GO:0061024,GO:0061025,GO:0061982,GO:0061988,GO:0065007,GO:0070192,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090407,GO:0090501,GO:0090502,GO:0098588,GO:0098805,GO:0098827,GO:0140098,GO:1901360,GO:1901576,GO:1903046,GO:1990904 - 0.0000002946 64.0
HKD1_k127_4140166_33 peptidase C11 clostripain - - - 0.00002438 58.0
HKD1_k127_4140166_4 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 437.0
HKD1_k127_4140166_5 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 417.0
HKD1_k127_4140166_6 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 369.0
HKD1_k127_4140166_7 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 310.0
HKD1_k127_4140166_8 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006075 304.0
HKD1_k127_4140166_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001837 284.0
HKD1_k127_4146374_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1096.0
HKD1_k127_4146374_1 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 7.447e-265 853.0
HKD1_k127_4146374_10 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 494.0
HKD1_k127_4146374_11 acetyl-CoA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 489.0
HKD1_k127_4146374_12 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 423.0
HKD1_k127_4146374_13 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 424.0
HKD1_k127_4146374_14 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 409.0
HKD1_k127_4146374_15 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 390.0
HKD1_k127_4146374_16 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 303.0
HKD1_k127_4146374_17 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
HKD1_k127_4146374_18 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000001254 182.0
HKD1_k127_4146374_19 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000003284 175.0
HKD1_k127_4146374_2 CarboxypepD_reg-like domain - - - 2.605e-241 766.0
HKD1_k127_4146374_20 DinB superfamily - - - 0.0000000000000000000000000000000000000000000006745 171.0
HKD1_k127_4146374_21 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000001438 184.0
HKD1_k127_4146374_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000007902 148.0
HKD1_k127_4146374_23 Transposase - - - 0.000000000000000001561 85.0
HKD1_k127_4146374_3 Carboxypeptidase regulatory-like domain - - - 1.118e-238 778.0
HKD1_k127_4146374_4 radical SAM domain protein K22318 - - 4.516e-229 722.0
HKD1_k127_4146374_5 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 1.009e-225 709.0
HKD1_k127_4146374_6 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 2.094e-206 647.0
HKD1_k127_4146374_7 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.298e-194 627.0
HKD1_k127_4146374_8 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
HKD1_k127_4146374_9 Major facilitator superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 534.0
HKD1_k127_4166762_0 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000007676 232.0
HKD1_k127_4166762_1 helix_turn_helix, Lux Regulon K07684,K07693 - - 0.0003237 50.0
HKD1_k127_4183577_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 5.101e-194 629.0
HKD1_k127_41900_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 483.0
HKD1_k127_41900_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 452.0
HKD1_k127_41900_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
HKD1_k127_41900_3 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
HKD1_k127_41900_4 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
HKD1_k127_41900_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000001417 129.0
HKD1_k127_4208952_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 540.0
HKD1_k127_4208952_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
HKD1_k127_4208952_2 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.00000000000000000000000000000000000000000001071 169.0
HKD1_k127_4208952_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000001321 126.0
HKD1_k127_4208952_4 Lysin motif - - - 0.00000000000000000000000153 108.0
HKD1_k127_420910_0 DEAD DEAH box K03724 - - 0.0 1918.0
HKD1_k127_420910_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.348e-275 869.0
HKD1_k127_420910_10 Signal transducing histidine kinase, homodimeric K02487,K03407,K06596 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 598.0
HKD1_k127_420910_11 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 535.0
HKD1_k127_420910_12 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 550.0
HKD1_k127_420910_13 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 542.0
HKD1_k127_420910_14 Peptidase, M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 538.0
HKD1_k127_420910_15 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 504.0
HKD1_k127_420910_16 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 495.0
HKD1_k127_420910_17 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 470.0
HKD1_k127_420910_18 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 454.0
HKD1_k127_420910_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 476.0
HKD1_k127_420910_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.767e-251 805.0
HKD1_k127_420910_20 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 415.0
HKD1_k127_420910_21 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
HKD1_k127_420910_22 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 397.0
HKD1_k127_420910_23 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 392.0
HKD1_k127_420910_24 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 385.0
HKD1_k127_420910_25 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 376.0
HKD1_k127_420910_26 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 377.0
HKD1_k127_420910_27 WD40-like Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 367.0
HKD1_k127_420910_28 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 349.0
HKD1_k127_420910_29 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 348.0
HKD1_k127_420910_3 Phosphate acyltransferases K01897 - 6.2.1.3 4.864e-247 788.0
HKD1_k127_420910_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 319.0
HKD1_k127_420910_31 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001917 301.0
HKD1_k127_420910_32 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003522 288.0
HKD1_k127_420910_33 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
HKD1_k127_420910_34 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001497 288.0
HKD1_k127_420910_35 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006159 280.0
HKD1_k127_420910_36 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002454 281.0
HKD1_k127_420910_37 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000041 272.0
HKD1_k127_420910_38 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000007473 268.0
HKD1_k127_420910_39 polysaccharide deacetylase K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
HKD1_k127_420910_4 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 4.97e-247 777.0
HKD1_k127_420910_40 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002149 260.0
HKD1_k127_420910_41 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007365 257.0
HKD1_k127_420910_42 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009197 269.0
HKD1_k127_420910_43 PAS domain containing protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000004793 254.0
HKD1_k127_420910_44 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000003767 255.0
HKD1_k127_420910_45 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000004996 237.0
HKD1_k127_420910_46 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
HKD1_k127_420910_47 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
HKD1_k127_420910_48 - - - - 0.0000000000000000000000000000000000000000000000000000000000007077 216.0
HKD1_k127_420910_49 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000003721 214.0
HKD1_k127_420910_5 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.938e-230 728.0
HKD1_k127_420910_50 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000002405 219.0
HKD1_k127_420910_51 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000004255 207.0
HKD1_k127_420910_52 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000008915 213.0
HKD1_k127_420910_53 lyase activity K03301 - - 0.000000000000000000000000000000000000000000000000000000441 220.0
HKD1_k127_420910_54 phosphatidylcholine synthase K01004 - 2.7.8.24 0.000000000000000000000000000000000000000000000000008918 188.0
HKD1_k127_420910_55 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000009933 177.0
HKD1_k127_420910_56 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000004426 161.0
HKD1_k127_420910_57 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000663 156.0
HKD1_k127_420910_58 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000000000007379 154.0
HKD1_k127_420910_59 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575,K02661 - 2.1.1.80 0.0000000000000000000000000000000000002376 152.0
HKD1_k127_420910_6 efflux transmembrane transporter activity - - - 2.772e-225 723.0
HKD1_k127_420910_60 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000001592 143.0
HKD1_k127_420910_61 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000008194 157.0
HKD1_k127_420910_62 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000007029 150.0
HKD1_k127_420910_63 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000001376 139.0
HKD1_k127_420910_64 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000006015 145.0
HKD1_k127_420910_65 - - - - 0.0000000000000000000000000000003602 139.0
HKD1_k127_420910_66 DoxX - - - 0.000000000000000000000000000001538 124.0
HKD1_k127_420910_67 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000001363 130.0
HKD1_k127_420910_68 Tetratricopeptide repeat - - - 0.0000000000000000000000000006999 130.0
HKD1_k127_420910_69 - - - - 0.000000000000000000000000001001 117.0
HKD1_k127_420910_7 PFAM Radical SAM - - - 6.011e-220 694.0
HKD1_k127_420910_70 - - - - 0.000000000000000000000000002513 116.0
HKD1_k127_420910_71 - - - - 0.0000000000000000000000005535 117.0
HKD1_k127_420910_72 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000008094 118.0
HKD1_k127_420910_73 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000002093 118.0
HKD1_k127_420910_74 - - - - 0.00000000000000000000002307 106.0
HKD1_k127_420910_75 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.000000000000000000003138 109.0
HKD1_k127_420910_76 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000208 94.0
HKD1_k127_420910_77 Belongs to the GPAT DAPAT family K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.00000000000000000008419 102.0
HKD1_k127_420910_78 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000005359 98.0
HKD1_k127_420910_79 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576 3.5.99.10 0.00000000000000002938 95.0
HKD1_k127_420910_8 Lamin Tail Domain K07004 - - 2.522e-217 713.0
HKD1_k127_420910_80 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000004172 88.0
HKD1_k127_420910_81 response regulator, receiver - - - 0.0000000000000002919 84.0
HKD1_k127_420910_82 protein transport - - - 0.0000000000001261 74.0
HKD1_k127_420910_83 chemotaxis protein K03408 - - 0.0000000000001878 80.0
HKD1_k127_420910_85 Regulatory protein, FmdB family - - - 0.00000000009672 64.0
HKD1_k127_420910_86 Tetratricopeptide repeat - - - 0.000000000537 72.0
HKD1_k127_420910_87 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000003341 56.0
HKD1_k127_420910_88 endoribonuclease L-PSP - - - 0.0000002965 63.0
HKD1_k127_420910_89 PFAM Lysylphosphatidylglycerol synthetase K07027 - - 0.000002014 60.0
HKD1_k127_420910_9 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 583.0
HKD1_k127_4217513_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.468e-199 632.0
HKD1_k127_4217513_1 Pfam Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 255.0
HKD1_k127_4232125_0 Autotransporter beta-domain - - - 1.804e-260 897.0
HKD1_k127_4232125_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 7.351e-225 726.0
HKD1_k127_4232125_10 chlorophyll binding K03286,K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000004017 235.0
HKD1_k127_4232125_11 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
HKD1_k127_4232125_12 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001177 206.0
HKD1_k127_4232125_13 - - - - 0.000000000000000000000000000000000000000001319 168.0
HKD1_k127_4232125_14 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000005784 148.0
HKD1_k127_4232125_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000997 139.0
HKD1_k127_4232125_16 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000002863 133.0
HKD1_k127_4232125_17 membrane - - - 0.00000000000000000000000008187 116.0
HKD1_k127_4232125_18 hydroperoxide reductase activity - - - 0.0000000000000000000000003116 108.0
HKD1_k127_4232125_19 Haem-binding domain - - - 0.00000000000000000000000321 111.0
HKD1_k127_4232125_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 627.0
HKD1_k127_4232125_20 GyrI-like small molecule binding domain - - - 0.000000000000000000000142 108.0
HKD1_k127_4232125_22 hydroperoxide reductase activity - - - 0.000000000000000004986 92.0
HKD1_k127_4232125_24 ACT domain protein - - - 0.0000000006118 65.0
HKD1_k127_4232125_26 - - - - 0.000001389 53.0
HKD1_k127_4232125_27 subunit of a heme lyase K02200 - - 0.0001812 47.0
HKD1_k127_4232125_28 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.0003507 45.0
HKD1_k127_4232125_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 488.0
HKD1_k127_4232125_4 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 372.0
HKD1_k127_4232125_5 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 395.0
HKD1_k127_4232125_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 371.0
HKD1_k127_4232125_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 302.0
HKD1_k127_4232125_8 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003809 261.0
HKD1_k127_4232125_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005043 249.0
HKD1_k127_423667_0 CarboxypepD_reg-like domain - - - 3.05e-212 697.0
HKD1_k127_423667_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 606.0
HKD1_k127_423667_10 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 467.0
HKD1_k127_423667_11 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 436.0
HKD1_k127_423667_12 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 435.0
HKD1_k127_423667_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 439.0
HKD1_k127_423667_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 404.0
HKD1_k127_423667_15 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 413.0
HKD1_k127_423667_16 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 400.0
HKD1_k127_423667_17 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 385.0
HKD1_k127_423667_18 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 387.0
HKD1_k127_423667_19 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
HKD1_k127_423667_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 552.0
HKD1_k127_423667_20 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 383.0
HKD1_k127_423667_21 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 376.0
HKD1_k127_423667_22 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 375.0
HKD1_k127_423667_23 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 395.0
HKD1_k127_423667_24 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 370.0
HKD1_k127_423667_25 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 354.0
HKD1_k127_423667_26 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 347.0
HKD1_k127_423667_27 methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
HKD1_k127_423667_28 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 308.0
HKD1_k127_423667_29 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 305.0
HKD1_k127_423667_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 570.0
HKD1_k127_423667_30 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 298.0
HKD1_k127_423667_31 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 285.0
HKD1_k127_423667_32 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 257.0
HKD1_k127_423667_33 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000001826 255.0
HKD1_k127_423667_34 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000005732 262.0
HKD1_k127_423667_35 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000001111 254.0
HKD1_k127_423667_36 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000006753 242.0
HKD1_k127_423667_37 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001644 245.0
HKD1_k127_423667_38 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000001953 221.0
HKD1_k127_423667_39 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000001137 205.0
HKD1_k127_423667_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 559.0
HKD1_k127_423667_40 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000005039 198.0
HKD1_k127_423667_41 Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing - - - 0.00000000000000000000000000000000000000000000000008 196.0
HKD1_k127_423667_42 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000001146 190.0
HKD1_k127_423667_43 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000002163 190.0
HKD1_k127_423667_44 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000001995 177.0
HKD1_k127_423667_45 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000002831 175.0
HKD1_k127_423667_46 MFS_1 like family - - - 0.00000000000000000000000000000000000000000008566 181.0
HKD1_k127_423667_47 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000002166 149.0
HKD1_k127_423667_48 thioesterase K07107 - - 0.00000000000000000000000000000000000001378 147.0
HKD1_k127_423667_49 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000009505 149.0
HKD1_k127_423667_5 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 517.0
HKD1_k127_423667_50 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000001238 153.0
HKD1_k127_423667_51 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000156 143.0
HKD1_k127_423667_52 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000001796 139.0
HKD1_k127_423667_53 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000021 124.0
HKD1_k127_423667_54 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000000001205 122.0
HKD1_k127_423667_55 PASTA domain K12132 - 2.7.11.1 0.0000000000000000000000003769 114.0
HKD1_k127_423667_56 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000001041 107.0
HKD1_k127_423667_57 Tetratricopeptide repeat K05807 - - 0.00000000000000000000002878 111.0
HKD1_k127_423667_58 - - - - 0.0000000000000000000001044 115.0
HKD1_k127_423667_59 oxidoreductase activity - - - 0.0000000000000000000004219 111.0
HKD1_k127_423667_6 PFAM ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 513.0
HKD1_k127_423667_60 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000474 108.0
HKD1_k127_423667_61 oxidoreductase activity - - - 0.00000000000000001823 97.0
HKD1_k127_423667_62 TPR repeat - - - 0.0000000000000002343 92.0
HKD1_k127_423667_63 regulatory protein, MerR - - - 0.0000000000002242 80.0
HKD1_k127_423667_64 Periplasmic copper-binding protein (NosD) - - - 0.00003364 56.0
HKD1_k127_423667_65 Acetyl-coenzyme A transporter 1 K08218 - - 0.00004835 51.0
HKD1_k127_423667_66 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.00007189 53.0
HKD1_k127_423667_67 Methyltransferase domain - - - 0.00008696 53.0
HKD1_k127_423667_68 Tetratricopeptide TPR_2 repeat protein - - - 0.0002365 53.0
HKD1_k127_423667_69 Sel1-like repeats. K07126 - - 0.0004116 53.0
HKD1_k127_423667_7 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 506.0
HKD1_k127_423667_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 491.0
HKD1_k127_423667_9 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 479.0
HKD1_k127_4248107_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000000002085 139.0
HKD1_k127_4248107_1 Belongs to the 'phage' integrase family - - - 0.0000000005493 71.0
HKD1_k127_4248107_2 domain, Protein K07277,K07278,K21449 - - 0.00000002065 65.0
HKD1_k127_4248107_3 - - - - 0.00001582 54.0
HKD1_k127_4248107_4 Belongs to the 'phage' integrase family - - - 0.00002025 51.0
HKD1_k127_4267691_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.032e-262 842.0
HKD1_k127_4267691_1 Peptidase family M1 domain K01256 - 3.4.11.2 6.846e-242 776.0
HKD1_k127_4267691_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002411 268.0
HKD1_k127_4267691_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000782 256.0
HKD1_k127_4267691_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 245.0
HKD1_k127_4267691_13 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000001005 248.0
HKD1_k127_4267691_14 diguanylate cyclase - - - 0.00000000000000000000000000000000009645 144.0
HKD1_k127_4267691_15 Dienelactone hydrolase family - - - 0.0000000000000000000000000001298 124.0
HKD1_k127_4267691_16 Protein of unknown function (DUF3810) - - - 0.000000000000000000000000000344 128.0
HKD1_k127_4267691_17 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000001887 125.0
HKD1_k127_4267691_18 calcium- and calmodulin-responsive adenylate cyclase activity K11005,K11029 GO:0001906,GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0006873,GO:0006874,GO:0006875,GO:0007204,GO:0008150,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0019725,GO:0019835,GO:0030003,GO:0031640,GO:0035821,GO:0042592,GO:0044179,GO:0044364,GO:0044419,GO:0044764,GO:0048878,GO:0050801,GO:0051480,GO:0051704,GO:0051715,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0098771 4.6.1.1 0.000000000000000000000002211 114.0
HKD1_k127_4267691_19 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000005289 74.0
HKD1_k127_4267691_2 Dienelactone hydrolase family - - - 3.531e-237 754.0
HKD1_k127_4267691_20 Protein conserved in bacteria K15539 - - 0.0000000006372 69.0
HKD1_k127_4267691_21 - - - - 0.00001387 56.0
HKD1_k127_4267691_22 Belongs to the ompA family K03286 - - 0.0001147 45.0
HKD1_k127_4267691_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 532.0
HKD1_k127_4267691_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 498.0
HKD1_k127_4267691_5 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 478.0
HKD1_k127_4267691_6 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 404.0
HKD1_k127_4267691_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 369.0
HKD1_k127_4267691_8 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 320.0
HKD1_k127_4267691_9 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 292.0
HKD1_k127_4269297_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000424 221.0
HKD1_k127_4269297_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000001778 216.0
HKD1_k127_4269297_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000009575 203.0
HKD1_k127_4269297_3 cheY-homologous receiver domain - - - 0.0000000000000001841 87.0
HKD1_k127_4302856_0 Multicopper oxidase K06324 - 1.16.3.3 1.483e-236 750.0
HKD1_k127_4302856_1 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 322.0
HKD1_k127_4302856_2 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 301.0
HKD1_k127_4302856_3 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
HKD1_k127_4302856_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000003806 235.0
HKD1_k127_4302856_5 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000001053 142.0
HKD1_k127_4302856_6 ABC-type antimicrobial peptide transport system, permease component - - - 0.0000000000000000000000000000001417 130.0
HKD1_k127_4328584_0 Aspartyl protease - - - 0.0000000000000000000000000000000000000000003396 172.0
HKD1_k127_4328584_1 TonB C terminal K03646 - - 0.0000000000000000000000000005645 118.0
HKD1_k127_4332440_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 471.0
HKD1_k127_4495482_0 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 485.0
HKD1_k127_4495482_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 383.0
HKD1_k127_4495482_10 - - - - 0.000000000000000000000000000000000000000000004272 168.0
HKD1_k127_4495482_11 Yip1 domain - - - 0.0000000000000000000000000000000000000000002183 165.0
HKD1_k127_4495482_12 Protein of unknown function, DUF393 - - - 0.000000000000000000000000004573 115.0
HKD1_k127_4495482_13 membrane - - - 0.00000000000000000003385 94.0
HKD1_k127_4495482_14 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000002795 101.0
HKD1_k127_4495482_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000002554 85.0
HKD1_k127_4495482_16 - - - - 0.00000000000241 72.0
HKD1_k127_4495482_17 Major facilitator superfamily - - - 0.00000000002243 66.0
HKD1_k127_4495482_2 Domain of unknown function DUF1828 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 322.0
HKD1_k127_4495482_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001842 272.0
HKD1_k127_4495482_4 recombinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007248 271.0
HKD1_k127_4495482_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
HKD1_k127_4495482_6 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000007077 232.0
HKD1_k127_4495482_7 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000002282 239.0
HKD1_k127_4495482_8 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000001448 225.0
HKD1_k127_4495482_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000001584 199.0
HKD1_k127_4518494_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 4.391e-242 777.0
HKD1_k127_4518494_1 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 606.0
HKD1_k127_4518494_10 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001331 261.0
HKD1_k127_4518494_11 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000001279 187.0
HKD1_k127_4518494_12 Ferredoxin - - - 0.0000000000000000008831 100.0
HKD1_k127_4518494_13 Redoxin - - - 0.00000000000002009 77.0
HKD1_k127_4518494_14 Alkyl hydroperoxide reductase - - - 0.0004132 44.0
HKD1_k127_4518494_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 513.0
HKD1_k127_4518494_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 458.0
HKD1_k127_4518494_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 441.0
HKD1_k127_4518494_5 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 407.0
HKD1_k127_4518494_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 388.0
HKD1_k127_4518494_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 398.0
HKD1_k127_4518494_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 332.0
HKD1_k127_4518494_9 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 342.0
HKD1_k127_4519476_0 Glycogen debranching enzyme - - - 0.0 1283.0
HKD1_k127_4519476_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1252.0
HKD1_k127_4519476_10 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 607.0
HKD1_k127_4519476_11 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 521.0
HKD1_k127_4519476_12 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 467.0
HKD1_k127_4519476_13 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 473.0
HKD1_k127_4519476_14 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 432.0
HKD1_k127_4519476_15 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 400.0
HKD1_k127_4519476_16 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 411.0
HKD1_k127_4519476_17 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 360.0
HKD1_k127_4519476_18 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 331.0
HKD1_k127_4519476_19 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 329.0
HKD1_k127_4519476_2 MacB-like periplasmic core domain - - - 1.923e-301 945.0
HKD1_k127_4519476_20 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 303.0
HKD1_k127_4519476_21 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000039 276.0
HKD1_k127_4519476_22 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002972 253.0
HKD1_k127_4519476_23 membrane - - - 0.0000000000000000000000000000000000000000000000000000000004727 209.0
HKD1_k127_4519476_24 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000004438 215.0
HKD1_k127_4519476_25 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000001286 178.0
HKD1_k127_4519476_26 - - - - 0.00000000000000000000000000000000000000701 146.0
HKD1_k127_4519476_27 epimerase - - - 0.0000000000000000000000000000000004133 142.0
HKD1_k127_4519476_28 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000004028 134.0
HKD1_k127_4519476_29 - - - - 0.00000000000000000000000000000001365 131.0
HKD1_k127_4519476_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.906e-275 861.0
HKD1_k127_4519476_30 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000007978 136.0
HKD1_k127_4519476_31 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000004637 125.0
HKD1_k127_4519476_32 hydroperoxide reductase activity K01607 - 4.1.1.44 0.00000000000000000000000000002312 119.0
HKD1_k127_4519476_33 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000001754 120.0
HKD1_k127_4519476_34 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000003244 107.0
HKD1_k127_4519476_35 - - - - 0.000000000000000000000004092 111.0
HKD1_k127_4519476_36 - - - - 0.00000000000000000000003491 108.0
HKD1_k127_4519476_37 ATP synthase delta (OSCP) subunit K02113 - - 0.00000000000000001153 88.0
HKD1_k127_4519476_38 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000000000000001235 82.0
HKD1_k127_4519476_39 ATP synthase subunit C K02110 - - 0.0000000000000001001 82.0
HKD1_k127_4519476_4 serine dehydratase beta chain K01752 - 4.3.1.17 9.346e-256 803.0
HKD1_k127_4519476_41 Domain of unknown function (DUF4136) - - - 0.000000002972 65.0
HKD1_k127_4519476_42 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.000009166 53.0
HKD1_k127_4519476_43 Ankyrin repeats (many copies) - - - 0.00004715 56.0
HKD1_k127_4519476_44 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.00006899 55.0
HKD1_k127_4519476_45 spectrin binding - - - 0.0001896 54.0
HKD1_k127_4519476_46 nuclease activity - - - 0.0008605 49.0
HKD1_k127_4519476_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.409e-233 728.0
HKD1_k127_4519476_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.289e-227 712.0
HKD1_k127_4519476_7 efflux transmembrane transporter activity - - - 6.381e-208 677.0
HKD1_k127_4519476_8 Fumarase C C-terminus K01744 - 4.3.1.1 2.667e-206 650.0
HKD1_k127_4519476_9 Tfp pilus assembly protein FimV - - - 6.956e-205 653.0
HKD1_k127_4562237_0 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 460.0
HKD1_k127_4562237_1 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000000000000000000001919 165.0
HKD1_k127_4562237_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000004928 164.0
HKD1_k127_4626771_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1349.0
HKD1_k127_4626771_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 407.0
HKD1_k127_4626771_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 382.0
HKD1_k127_4626771_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 322.0
HKD1_k127_4626771_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000002608 169.0
HKD1_k127_4626771_5 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000002156 172.0
HKD1_k127_4626771_6 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0007807 45.0
HKD1_k127_466553_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 586.0
HKD1_k127_466553_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 314.0
HKD1_k127_466553_2 8-amino-7-oxononanoate synthase activity K00639,K00652,K10915 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000002798 263.0
HKD1_k127_4683753_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 609.0
HKD1_k127_4683753_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 560.0
HKD1_k127_4683753_10 - - - - 0.00000000000000001234 92.0
HKD1_k127_4683753_11 phosphorelay signal transduction system - - - 0.0000000000001143 79.0
HKD1_k127_4683753_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 518.0
HKD1_k127_4683753_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 352.0
HKD1_k127_4683753_4 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000707 294.0
HKD1_k127_4683753_5 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HKD1_k127_4683753_6 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000004157 211.0
HKD1_k127_4683753_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000005942 179.0
HKD1_k127_4683753_8 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000004743 156.0
HKD1_k127_4683753_9 histone methyltransferase activity (H3-K4 specific) K09186,K09188,K22197 - 2.1.1.43 0.000000000000000000000000003397 122.0
HKD1_k127_4719996_0 response regulator - - - 2.951e-197 623.0
HKD1_k127_4719996_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 521.0
HKD1_k127_4719996_10 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000004614 153.0
HKD1_k127_4719996_11 OmpA family - - - 0.0000000000000000000000000000000002226 143.0
HKD1_k127_4719996_12 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000005858 131.0
HKD1_k127_4719996_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000005605 133.0
HKD1_k127_4719996_14 FecR protein - - - 0.000000000000000000000000002173 118.0
HKD1_k127_4719996_16 - - - - 0.000000000000003871 86.0
HKD1_k127_4719996_18 - - - - 0.00000000003378 70.0
HKD1_k127_4719996_2 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 481.0
HKD1_k127_4719996_21 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0004854 50.0
HKD1_k127_4719996_22 domain protein - - - 0.0008268 51.0
HKD1_k127_4719996_23 - - - - 0.0009361 52.0
HKD1_k127_4719996_3 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 384.0
HKD1_k127_4719996_4 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 366.0
HKD1_k127_4719996_5 Chase2 domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000006138 231.0
HKD1_k127_4719996_6 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000004438 169.0
HKD1_k127_4719996_7 Domain of unknown function (DUF4034) - - - 0.0000000000000000000000000000000000000000759 169.0
HKD1_k127_4719996_8 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000007964 153.0
HKD1_k127_4719996_9 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000002993 151.0
HKD1_k127_4723397_0 Bacterial extracellular solute-binding protein K02027 - - 1.124e-200 635.0
HKD1_k127_4723397_1 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 499.0
HKD1_k127_4723397_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 479.0
HKD1_k127_4723397_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000003436 164.0
HKD1_k127_4723397_4 TOBE domain K10112 - - 0.0000001623 53.0
HKD1_k127_4730018_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 5.986e-260 819.0
HKD1_k127_4730018_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 571.0
HKD1_k127_4730018_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
HKD1_k127_4730018_3 pfam rok - - - 0.00000000000000000000000000000000000000000000000001894 195.0
HKD1_k127_4730018_4 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0000000000000000004087 103.0
HKD1_k127_4730018_5 ASPIC and UnbV - - - 0.00000003371 65.0
HKD1_k127_47632_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 500.0
HKD1_k127_47632_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 402.0
HKD1_k127_47632_2 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 315.0
HKD1_k127_47632_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
HKD1_k127_47632_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000004941 98.0
HKD1_k127_4829490_0 serine-type peptidase activity - - - 0.0 1131.0
HKD1_k127_4829490_1 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1066.0
HKD1_k127_4829490_2 MacB-like periplasmic core domain - - - 0.0 1040.0
HKD1_k127_4829490_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002021 283.0
HKD1_k127_4829490_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000308 191.0
HKD1_k127_4829490_5 CoA binding domain K06929 - - 0.000000000000000000000000000000003308 135.0
HKD1_k127_4864224_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1365.0
HKD1_k127_4864224_1 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 4.232e-215 684.0
HKD1_k127_4864224_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 338.0
HKD1_k127_4864224_11 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 333.0
HKD1_k127_4864224_12 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 293.0
HKD1_k127_4864224_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 294.0
HKD1_k127_4864224_14 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 291.0
HKD1_k127_4864224_15 Peptidase S9 prolyl oligopeptidase active site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003345 282.0
HKD1_k127_4864224_16 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
HKD1_k127_4864224_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000001501 215.0
HKD1_k127_4864224_18 PFAM Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000001975 203.0
HKD1_k127_4864224_19 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000002911 174.0
HKD1_k127_4864224_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.94e-201 638.0
HKD1_k127_4864224_20 - - - - 0.000000003484 69.0
HKD1_k127_4864224_3 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 8.996e-197 625.0
HKD1_k127_4864224_4 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.319e-195 621.0
HKD1_k127_4864224_5 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 613.0
HKD1_k127_4864224_6 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 539.0
HKD1_k127_4864224_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 466.0
HKD1_k127_4864224_8 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 410.0
HKD1_k127_4864224_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 389.0
HKD1_k127_4891510_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 589.0
HKD1_k127_4891510_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 469.0
HKD1_k127_4891510_10 - - - - 0.000000000000064 86.0
HKD1_k127_4891510_2 Polysaccharide pyruvyl transferase K16710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 306.0
HKD1_k127_4891510_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 296.0
HKD1_k127_4891510_4 BtpA family K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002694 286.0
HKD1_k127_4891510_5 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
HKD1_k127_4891510_6 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
HKD1_k127_4891510_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004833 224.0
HKD1_k127_4891510_8 Belongs to the carbohydrate kinase PfkB family K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.213 0.000000000000000000000000002041 123.0
HKD1_k127_4891510_9 - - - - 0.000000000000001168 89.0
HKD1_k127_4912724_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1198.0
HKD1_k127_4912724_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 441.0
HKD1_k127_4912724_10 DNA-templated transcription, initiation K03088 - - 0.00005348 53.0
HKD1_k127_4912724_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 425.0
HKD1_k127_4912724_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 392.0
HKD1_k127_4912724_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
HKD1_k127_4912724_5 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000002601 159.0
HKD1_k127_4912724_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000003706 130.0
HKD1_k127_4912724_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000551 125.0
HKD1_k127_4912724_8 Belongs to the Nudix hydrolase family - - - 0.0000000000000001897 87.0
HKD1_k127_4912724_9 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000006047 57.0
HKD1_k127_4919493_0 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000000002439 178.0
HKD1_k127_4919493_1 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000008109 117.0
HKD1_k127_4919493_2 pyridoxamine 5-phosphate - - - 0.0000000000000000001736 94.0
HKD1_k127_4994866_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 7.35e-289 899.0
HKD1_k127_4994866_1 PFAM Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 578.0
HKD1_k127_4994866_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000009132 189.0
HKD1_k127_4994866_3 Belongs to the UPF0235 family K09131 - - 0.0000002482 55.0
HKD1_k127_5032136_0 photosystem II stabilization - - - 5.345e-247 779.0
HKD1_k127_5049115_0 Amidohydrolase family - - - 1.609e-227 712.0
HKD1_k127_5049115_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 506.0
HKD1_k127_5049115_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 404.0
HKD1_k127_5057624_0 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K02805,K13017,K18653 - 2.6.1.104,2.6.1.59,2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 476.0
HKD1_k127_5057624_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 366.0
HKD1_k127_5057624_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 296.0
HKD1_k127_5057624_3 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002877 243.0
HKD1_k127_5057624_4 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000002509 223.0
HKD1_k127_5057624_5 - - - - 0.000000000000000000000000000000000001312 159.0
HKD1_k127_5057624_6 Probably functions as a manganese efflux pump - - - 0.0000000000000000000005893 110.0
HKD1_k127_5057624_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000002737 81.0
HKD1_k127_5063817_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 469.0
HKD1_k127_5063817_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 322.0
HKD1_k127_5063817_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000004179 218.0
HKD1_k127_5063817_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000002909 196.0
HKD1_k127_5063817_4 B3/4 domain - - - 0.00000000000000000000000000000002246 136.0
HKD1_k127_5063817_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000008705 86.0
HKD1_k127_5104561_0 Sortilin, neurotensin receptor 3, - - - 0.0 1327.0
HKD1_k127_5104561_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1016.0
HKD1_k127_5104561_10 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
HKD1_k127_5104561_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000009594 228.0
HKD1_k127_5104561_12 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
HKD1_k127_5104561_13 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000002487 214.0
HKD1_k127_5104561_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000009399 175.0
HKD1_k127_5104561_15 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000000000000000000000000002326 180.0
HKD1_k127_5104561_16 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000004996 162.0
HKD1_k127_5104561_17 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000008339 149.0
HKD1_k127_5104561_18 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000009114 128.0
HKD1_k127_5104561_19 - - - - 0.00000000000000000000000000000001096 130.0
HKD1_k127_5104561_2 Acetolactate synthase K00156,K01652 - 1.2.5.1,2.2.1.6 2.06e-244 769.0
HKD1_k127_5104561_20 - - - - 0.0000000000000000000000000003399 119.0
HKD1_k127_5104561_21 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000004013 119.0
HKD1_k127_5104561_22 - - - - 0.0000000000000000003959 90.0
HKD1_k127_5104561_23 negative regulation of transcription, DNA-templated - - - 0.000000000000000006998 94.0
HKD1_k127_5104561_24 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000009001 77.0
HKD1_k127_5104561_25 - - - - 0.0000003296 57.0
HKD1_k127_5104561_26 CARDB - - - 0.00000052 57.0
HKD1_k127_5104561_27 Belongs to the UPF0337 (CsbD) family - - - 0.000007018 51.0
HKD1_k127_5104561_3 Proposed role in polysaccahride synthesis K07077 - - 6.639e-220 694.0
HKD1_k127_5104561_4 PFAM peptidase - - - 1.655e-203 650.0
HKD1_k127_5104561_5 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 551.0
HKD1_k127_5104561_6 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 462.0
HKD1_k127_5104561_7 Amidase K01426,K21801 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 460.0
HKD1_k127_5104561_8 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 363.0
HKD1_k127_5104561_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 324.0
HKD1_k127_5173309_0 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000003166 135.0
HKD1_k127_5173309_1 - - - - 0.000000000000000000000000001019 119.0
HKD1_k127_5173309_2 PFAM Helix-turn-helix K07729 - - 0.000000000000000002196 86.0
HKD1_k127_5173309_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000005018 78.0
HKD1_k127_5173309_4 Peptidase family M48 - - - 0.000000000000001227 83.0
HKD1_k127_5183381_0 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 455.0
HKD1_k127_5183381_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
HKD1_k127_5183381_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000287 203.0
HKD1_k127_5183381_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08738 - - 0.00000000000000000000000000000000000000000000000000005117 192.0
HKD1_k127_5183381_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000003036 74.0
HKD1_k127_5221629_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 517.0
HKD1_k127_5221629_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 458.0
HKD1_k127_5221629_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 414.0
HKD1_k127_5221629_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000002511 214.0
HKD1_k127_5221629_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000001168 209.0
HKD1_k127_5221629_5 proteolysis - - - 0.0000000000000000000000000000002057 132.0
HKD1_k127_5237643_0 Methionine synthase K00548 - 2.1.1.13 0.0 1495.0
HKD1_k127_5237643_1 metallocarboxypeptidase activity K14054 - - 0.0 1218.0
HKD1_k127_5237643_10 Oligopeptidase F K08602 - - 2.199e-209 671.0
HKD1_k127_5237643_11 radical SAM domain protein - - - 1.033e-206 656.0
HKD1_k127_5237643_12 PFAM Prolyl oligopeptidase family - - - 6.592e-202 649.0
HKD1_k127_5237643_13 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 573.0
HKD1_k127_5237643_14 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 512.0
HKD1_k127_5237643_15 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 486.0
HKD1_k127_5237643_16 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 467.0
HKD1_k127_5237643_17 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 461.0
HKD1_k127_5237643_18 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 413.0
HKD1_k127_5237643_19 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 410.0
HKD1_k127_5237643_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1082.0
HKD1_k127_5237643_20 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 392.0
HKD1_k127_5237643_21 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 399.0
HKD1_k127_5237643_22 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 412.0
HKD1_k127_5237643_23 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 406.0
HKD1_k127_5237643_24 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 387.0
HKD1_k127_5237643_25 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 371.0
HKD1_k127_5237643_26 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 352.0
HKD1_k127_5237643_27 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 338.0
HKD1_k127_5237643_28 aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 334.0
HKD1_k127_5237643_29 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 335.0
HKD1_k127_5237643_3 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 8.184e-317 996.0
HKD1_k127_5237643_30 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 330.0
HKD1_k127_5237643_31 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 323.0
HKD1_k127_5237643_32 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 319.0
HKD1_k127_5237643_33 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 321.0
HKD1_k127_5237643_34 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 298.0
HKD1_k127_5237643_35 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 289.0
HKD1_k127_5237643_36 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 303.0
HKD1_k127_5237643_37 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
HKD1_k127_5237643_38 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 301.0
HKD1_k127_5237643_39 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000008119 265.0
HKD1_k127_5237643_4 Glutamine synthetase type III K01915 - 6.3.1.2 7.256e-309 963.0
HKD1_k127_5237643_40 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
HKD1_k127_5237643_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001966 237.0
HKD1_k127_5237643_42 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000002804 243.0
HKD1_k127_5237643_43 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
HKD1_k127_5237643_44 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000006628 238.0
HKD1_k127_5237643_45 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000351 228.0
HKD1_k127_5237643_46 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000005119 227.0
HKD1_k127_5237643_47 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000005684 204.0
HKD1_k127_5237643_48 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000008006 205.0
HKD1_k127_5237643_49 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000003229 211.0
HKD1_k127_5237643_5 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 1.423e-279 872.0
HKD1_k127_5237643_50 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000000000000000003064 200.0
HKD1_k127_5237643_51 Nicotinamide mononucleotide transporter - - - 0.00000000000000000000000000000000000000000000000000001446 198.0
HKD1_k127_5237643_52 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000001538 198.0
HKD1_k127_5237643_53 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000002688 196.0
HKD1_k127_5237643_54 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000008013 195.0
HKD1_k127_5237643_55 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000002118 192.0
HKD1_k127_5237643_56 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000002812 200.0
HKD1_k127_5237643_57 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000006824 171.0
HKD1_k127_5237643_58 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000001368 177.0
HKD1_k127_5237643_59 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000002456 175.0
HKD1_k127_5237643_6 topoisomerase K02469 - 5.99.1.3 1.493e-279 886.0
HKD1_k127_5237643_60 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000003943 163.0
HKD1_k127_5237643_61 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000004215 148.0
HKD1_k127_5237643_62 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000009016 150.0
HKD1_k127_5237643_63 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000001672 139.0
HKD1_k127_5237643_64 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000001636 146.0
HKD1_k127_5237643_65 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000004766 140.0
HKD1_k127_5237643_66 TOBE domain - - - 0.000000000000000000000000000000005084 134.0
HKD1_k127_5237643_67 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000001393 134.0
HKD1_k127_5237643_68 COG1555 DNA uptake protein and related DNA-binding proteins - - - 0.00000000000000000000000000000001951 145.0
HKD1_k127_5237643_69 DinB superfamily - - - 0.00000000000000000000000000000008562 130.0
HKD1_k127_5237643_7 PFAM LmbE family protein K22136 - - 9.94e-273 869.0
HKD1_k127_5237643_70 BMC domain - - - 0.0000000000000000000000000000001035 128.0
HKD1_k127_5237643_71 WHG domain - - - 0.00000000000000000000000000001344 126.0
HKD1_k127_5237643_72 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000002204 121.0
HKD1_k127_5237643_73 FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000002561 128.0
HKD1_k127_5237643_74 metal cluster binding - - - 0.000000000000000000000000003423 119.0
HKD1_k127_5237643_75 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000107 97.0
HKD1_k127_5237643_76 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.00000000000000000005991 104.0
HKD1_k127_5237643_77 helix_turn_helix, mercury resistance - - - 0.000000000000000001724 93.0
HKD1_k127_5237643_78 hyperosmotic response - - - 0.00000000000002101 85.0
HKD1_k127_5237643_79 - - - - 0.0000000000004319 74.0
HKD1_k127_5237643_8 AcrB/AcrD/AcrF family K03296 - - 1.183e-236 786.0
HKD1_k127_5237643_80 Alanine racemase - - - 0.0000000000005705 70.0
HKD1_k127_5237643_81 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000001026 66.0
HKD1_k127_5237643_9 serine-type peptidase activity K01278 - 3.4.14.5 1.18e-224 718.0
HKD1_k127_5263857_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1043.0
HKD1_k127_5263857_1 MacB-like periplasmic core domain - - - 0.0 1036.0
HKD1_k127_5263857_10 Protein kinase domain K12132 - 2.7.11.1 4.536e-231 748.0
HKD1_k127_5263857_11 peptidyl-tyrosine sulfation - - - 4.999e-231 726.0
HKD1_k127_5263857_12 PFAM glycoside hydrolase family 1 K05350 - 3.2.1.21 5.652e-229 718.0
HKD1_k127_5263857_13 Receptor family ligand binding region - - - 1.294e-224 711.0
HKD1_k127_5263857_14 peptidase activity, acting on L-amino acid peptides K09607 - - 2.616e-217 703.0
HKD1_k127_5263857_15 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 5.637e-217 704.0
HKD1_k127_5263857_16 Amidohydrolase family - - - 1.346e-202 640.0
HKD1_k127_5263857_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 563.0
HKD1_k127_5263857_18 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 594.0
HKD1_k127_5263857_19 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 544.0
HKD1_k127_5263857_2 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1018.0
HKD1_k127_5263857_20 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 499.0
HKD1_k127_5263857_21 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 494.0
HKD1_k127_5263857_22 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 501.0
HKD1_k127_5263857_23 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 498.0
HKD1_k127_5263857_24 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 447.0
HKD1_k127_5263857_25 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 396.0
HKD1_k127_5263857_26 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 385.0
HKD1_k127_5263857_27 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 376.0
HKD1_k127_5263857_28 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 374.0
HKD1_k127_5263857_29 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 349.0
HKD1_k127_5263857_3 Hydrolase CocE NonD family - - - 9.232e-307 950.0
HKD1_k127_5263857_30 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 345.0
HKD1_k127_5263857_31 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 344.0
HKD1_k127_5263857_32 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 343.0
HKD1_k127_5263857_33 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 346.0
HKD1_k127_5263857_35 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 333.0
HKD1_k127_5263857_36 RES - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 301.0
HKD1_k127_5263857_37 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007353 278.0
HKD1_k127_5263857_38 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005437 291.0
HKD1_k127_5263857_39 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005015 270.0
HKD1_k127_5263857_4 Malate synthase K01638 - 2.3.3.9 1.671e-299 929.0
HKD1_k127_5263857_40 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003674 273.0
HKD1_k127_5263857_41 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002673 252.0
HKD1_k127_5263857_42 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000326 269.0
HKD1_k127_5263857_43 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD1_k127_5263857_44 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000001141 232.0
HKD1_k127_5263857_45 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000001093 237.0
HKD1_k127_5263857_46 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
HKD1_k127_5263857_47 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000000006743 231.0
HKD1_k127_5263857_48 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD1_k127_5263857_49 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000186 226.0
HKD1_k127_5263857_5 ASPIC and UnbV - - - 8.941e-263 827.0
HKD1_k127_5263857_50 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000004048 225.0
HKD1_k127_5263857_51 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000002794 214.0
HKD1_k127_5263857_52 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000005204 207.0
HKD1_k127_5263857_53 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002308 205.0
HKD1_k127_5263857_54 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000002833 209.0
HKD1_k127_5263857_55 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000000000000000001145 190.0
HKD1_k127_5263857_56 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000004645 184.0
HKD1_k127_5263857_57 - - - - 0.000000000000000000000000000000000000000000000001297 181.0
HKD1_k127_5263857_58 LysM domain - - - 0.000000000000000000000000000000000000000000000431 174.0
HKD1_k127_5263857_59 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000006421 173.0
HKD1_k127_5263857_6 Voltage gated chloride channel - - - 2.032e-254 805.0
HKD1_k127_5263857_60 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000002628 160.0
HKD1_k127_5263857_61 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000297 150.0
HKD1_k127_5263857_62 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000003819 136.0
HKD1_k127_5263857_63 negative regulation of transcription, DNA-templated K10947 - - 0.0000000000000000000000000004331 119.0
HKD1_k127_5263857_64 methyltransferase - - - 0.000000000000000000000000003956 119.0
HKD1_k127_5263857_65 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000007907 109.0
HKD1_k127_5263857_66 Psort location Cytoplasmic, score - - - 0.0000000000000552 84.0
HKD1_k127_5263857_67 membrane - - - 0.0000000000004815 78.0
HKD1_k127_5263857_68 Domain of unknown function (DUF4386) - - - 0.000000000001547 74.0
HKD1_k127_5263857_69 Cupin domain - - - 0.0000000001539 73.0
HKD1_k127_5263857_7 alpha beta alpha domain I K01835 - 5.4.2.2 1.354e-250 783.0
HKD1_k127_5263857_70 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00007279 50.0
HKD1_k127_5263857_8 amine dehydrogenase activity - - - 1.074e-239 759.0
HKD1_k127_5263857_9 B12 binding domain - - - 4.188e-233 729.0
HKD1_k127_5286477_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.046e-283 894.0
HKD1_k127_5286477_1 Dehydrogenase E1 component K11381 - 1.2.4.4 1.486e-277 889.0
HKD1_k127_5286477_10 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000002933 243.0
HKD1_k127_5286477_11 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000002582 218.0
HKD1_k127_5286477_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000002686 193.0
HKD1_k127_5286477_13 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000006478 139.0
HKD1_k127_5286477_14 - - - - 0.0000000000000000000000000000000001449 141.0
HKD1_k127_5286477_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000005641 136.0
HKD1_k127_5286477_16 Thioredoxin domain - - - 0.000000000000000000000000000001562 126.0
HKD1_k127_5286477_17 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.0000000000000000000000000004576 117.0
HKD1_k127_5286477_18 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.000000000000000000000001316 106.0
HKD1_k127_5286477_19 Gas vesicle protein K - - - 0.000000000000000000008724 102.0
HKD1_k127_5286477_2 GTP-binding protein TypA K06207 - - 9.122e-265 829.0
HKD1_k127_5286477_20 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000004786 96.0
HKD1_k127_5286477_21 Gas vesicle - - - 0.00000000000000001453 92.0
HKD1_k127_5286477_22 Histone deacetylase domain - - - 0.00000000000000004499 86.0
HKD1_k127_5286477_23 Thioredoxin domain - - - 0.000000000000000102 81.0
HKD1_k127_5286477_24 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000001184 85.0
HKD1_k127_5286477_25 - - - - 0.0000000000001394 81.0
HKD1_k127_5286477_26 HEAT repeats - - - 0.0000000000103 76.0
HKD1_k127_5286477_27 - - - - 0.00000000008574 66.0
HKD1_k127_5286477_29 - - - - 0.00000002381 66.0
HKD1_k127_5286477_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.53e-227 721.0
HKD1_k127_5286477_30 - - - - 0.00000144 57.0
HKD1_k127_5286477_31 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000004053 57.0
HKD1_k127_5286477_32 Gas vesicle protein - - - 0.0000532 49.0
HKD1_k127_5286477_4 His Kinase A (phosphoacceptor) domain - - - 2.391e-194 629.0
HKD1_k127_5286477_5 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 376.0
HKD1_k127_5286477_6 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
HKD1_k127_5286477_7 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 309.0
HKD1_k127_5286477_8 MarC family integral membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000006453 239.0
HKD1_k127_5286477_9 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000005009 231.0
HKD1_k127_5337702_0 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 357.0
HKD1_k127_5337702_1 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
HKD1_k127_5337702_2 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
HKD1_k127_5337702_3 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000004106 186.0
HKD1_k127_5337702_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000004101 173.0
HKD1_k127_5337702_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000002076 112.0
HKD1_k127_5337702_6 Patatin-like phospholipase - - - 0.000000000000000000007014 108.0
HKD1_k127_5386735_0 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 505.0
HKD1_k127_5393953_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.493e-231 743.0
HKD1_k127_5393953_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 396.0
HKD1_k127_5393953_2 imidazolonepropionase activity K15358 - 3.5.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003896 284.0
HKD1_k127_5393953_3 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000497 274.0
HKD1_k127_5393953_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000003756 115.0
HKD1_k127_5471783_0 metallopeptidase activity K01183 - 3.2.1.14 0.0 1069.0
HKD1_k127_5471783_1 secondary active sulfate transmembrane transporter activity K03321 - - 8.801e-278 863.0
HKD1_k127_5471783_2 Beta-galactosidase - - - 5.4e-205 651.0
HKD1_k127_5471783_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000001255 155.0
HKD1_k127_5471783_4 - K01865 - 5.4.4.1 0.000000000000000003363 91.0
HKD1_k127_5471783_6 - - - - 0.00004461 47.0
HKD1_k127_5492348_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 437.0
HKD1_k127_5492348_1 enoyl-CoA hydratase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HKD1_k127_5492348_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 332.0
HKD1_k127_5492348_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000003389 115.0
HKD1_k127_5501457_0 Sortilin, neurotensin receptor 3, - - - 0.0 1335.0
HKD1_k127_5501457_1 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1188.0
HKD1_k127_5501457_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 567.0
HKD1_k127_5501457_11 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 518.0
HKD1_k127_5501457_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 519.0
HKD1_k127_5501457_13 Aspartate alanine antiporter family protein 1 K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 511.0
HKD1_k127_5501457_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 468.0
HKD1_k127_5501457_15 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 463.0
HKD1_k127_5501457_16 Flavin-binding monooxygenase-like K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 449.0
HKD1_k127_5501457_17 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 456.0
HKD1_k127_5501457_18 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 437.0
HKD1_k127_5501457_19 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 426.0
HKD1_k127_5501457_2 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1049.0
HKD1_k127_5501457_20 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 426.0
HKD1_k127_5501457_21 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 416.0
HKD1_k127_5501457_22 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 409.0
HKD1_k127_5501457_23 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 409.0
HKD1_k127_5501457_24 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 394.0
HKD1_k127_5501457_25 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
HKD1_k127_5501457_26 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 370.0
HKD1_k127_5501457_27 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 347.0
HKD1_k127_5501457_28 PFAM Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 334.0
HKD1_k127_5501457_29 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 329.0
HKD1_k127_5501457_3 PFAM glycoside hydrolase 15-related K01178 - 3.2.1.3 5e-324 1010.0
HKD1_k127_5501457_30 Fe-S cluster domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
HKD1_k127_5501457_31 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 319.0
HKD1_k127_5501457_32 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005576 286.0
HKD1_k127_5501457_33 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000003238 260.0
HKD1_k127_5501457_34 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002157 233.0
HKD1_k127_5501457_35 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000002621 227.0
HKD1_k127_5501457_36 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000001723 225.0
HKD1_k127_5501457_37 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000000000000000000000000000000000000000000006709 222.0
HKD1_k127_5501457_38 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000007853 223.0
HKD1_k127_5501457_39 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000983 203.0
HKD1_k127_5501457_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.119e-310 957.0
HKD1_k127_5501457_40 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000005819 192.0
HKD1_k127_5501457_41 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000001294 192.0
HKD1_k127_5501457_42 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000001354 184.0
HKD1_k127_5501457_43 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000003595 192.0
HKD1_k127_5501457_44 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000002055 197.0
HKD1_k127_5501457_45 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000001608 188.0
HKD1_k127_5501457_46 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000088 202.0
HKD1_k127_5501457_47 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000001253 178.0
HKD1_k127_5501457_48 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000003776 184.0
HKD1_k127_5501457_49 Glycosyltransferase family 9 (heptosyltransferase) K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000005454 182.0
HKD1_k127_5501457_5 MacB-like periplasmic core domain - - - 2.359e-266 846.0
HKD1_k127_5501457_50 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000000000000000002115 163.0
HKD1_k127_5501457_51 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000001539 167.0
HKD1_k127_5501457_52 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000006895 175.0
HKD1_k127_5501457_53 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000001179 176.0
HKD1_k127_5501457_54 sigma factor antagonist activity K03458,K04757 - 2.7.11.1 0.000000000000000000000000000000000000002127 157.0
HKD1_k127_5501457_55 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000001786 157.0
HKD1_k127_5501457_56 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000367 138.0
HKD1_k127_5501457_57 TIGRFAM hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000966 139.0
HKD1_k127_5501457_58 DRTGG domain - - - 0.0000000000000000000000000001049 118.0
HKD1_k127_5501457_59 methyltransferase activity - - - 0.000000000000000000000107 104.0
HKD1_k127_5501457_6 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 8.202e-231 730.0
HKD1_k127_5501457_60 DRTGG domain - - - 0.0000000000000000009924 91.0
HKD1_k127_5501457_62 response to abiotic stimulus K03086,K06867,K06886 - - 0.0000000000000003988 81.0
HKD1_k127_5501457_63 cAMP biosynthetic process K03641 - - 0.00000000000005582 86.0
HKD1_k127_5501457_64 glycoside hydrolase family 2 sugar binding - - - 0.00000000000008104 78.0
HKD1_k127_5501457_65 response to abiotic stimulus K03086,K06867,K06886 - - 0.0000000000001089 76.0
HKD1_k127_5501457_66 PIN domain - - - 0.000000000001136 76.0
HKD1_k127_5501457_67 Preprotein translocase SecG subunit K03075 - - 0.0000000002561 66.0
HKD1_k127_5501457_7 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.524e-203 649.0
HKD1_k127_5501457_8 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 584.0
HKD1_k127_5501457_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 568.0
HKD1_k127_560106_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 318.0
HKD1_k127_560106_1 - - - - 0.000000000000000000000000000000000000000007922 158.0
HKD1_k127_5608095_0 hydrolase, family 3 K05349 - 3.2.1.21 2.06e-295 930.0
HKD1_k127_5608095_1 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.0000000000000000000000006239 108.0
HKD1_k127_5626249_0 MacB-like periplasmic core domain - - - 0.0 1049.0
HKD1_k127_5626249_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 4.762e-307 957.0
HKD1_k127_5626249_10 TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 421.0
HKD1_k127_5626249_11 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 417.0
HKD1_k127_5626249_12 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
HKD1_k127_5626249_13 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 311.0
HKD1_k127_5626249_14 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 284.0
HKD1_k127_5626249_15 PFAM Disulphide bond formation protein DsbB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003451 282.0
HKD1_k127_5626249_16 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 244.0
HKD1_k127_5626249_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001962 259.0
HKD1_k127_5626249_18 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000009198 190.0
HKD1_k127_5626249_19 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000008251 190.0
HKD1_k127_5626249_2 Oxidoreductase - - - 1.786e-270 845.0
HKD1_k127_5626249_20 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000001925 190.0
HKD1_k127_5626249_21 WYL domain K13572 - - 0.0000000000000000000000000000000000000000001031 173.0
HKD1_k127_5626249_22 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000007378 141.0
HKD1_k127_5626249_23 nuclease activity - - - 0.00000000000000000000000000000000001115 142.0
HKD1_k127_5626249_24 Putative restriction endonuclease - - - 0.0000000000000000000000000000001617 131.0
HKD1_k127_5626249_25 - - - - 0.00000000000000000000001067 107.0
HKD1_k127_5626249_26 - - - - 0.000000000000000005203 89.0
HKD1_k127_5626249_28 TIGRFAM TonB K03832 - - 0.000000000002914 74.0
HKD1_k127_5626249_29 Bacterial Ig-like domain 2 - - - 0.0000001432 63.0
HKD1_k127_5626249_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 9.421e-218 687.0
HKD1_k127_5626249_32 TPR repeat - - - 0.0001156 54.0
HKD1_k127_5626249_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.085e-196 633.0
HKD1_k127_5626249_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 593.0
HKD1_k127_5626249_6 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 572.0
HKD1_k127_5626249_7 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 575.0
HKD1_k127_5626249_8 Nucleoside H+ symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 480.0
HKD1_k127_5626249_9 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 461.0
HKD1_k127_5655872_0 Di-haem oxidoreductase, putative peroxidase - - - 3.692e-236 739.0
HKD1_k127_5655872_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 585.0
HKD1_k127_5655872_10 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 320.0
HKD1_k127_5655872_11 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 332.0
HKD1_k127_5655872_12 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004218 301.0
HKD1_k127_5655872_13 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
HKD1_k127_5655872_14 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001374 267.0
HKD1_k127_5655872_15 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009735 244.0
HKD1_k127_5655872_16 serine-type endopeptidase activity K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000002554 241.0
HKD1_k127_5655872_17 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002178 234.0
HKD1_k127_5655872_18 - - - - 0.0000000000000000000000000000000000000000009743 181.0
HKD1_k127_5655872_19 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000001724 151.0
HKD1_k127_5655872_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 516.0
HKD1_k127_5655872_20 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000009936 152.0
HKD1_k127_5655872_21 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000001246 126.0
HKD1_k127_5655872_22 metalloendopeptidase activity K03799 - - 0.000000000000000000000000003654 126.0
HKD1_k127_5655872_24 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000004478 81.0
HKD1_k127_5655872_25 Peptidase M56 K03646 - - 0.000000001482 66.0
HKD1_k127_5655872_26 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000007156 60.0
HKD1_k127_5655872_27 - - - - 0.0002447 49.0
HKD1_k127_5655872_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 516.0
HKD1_k127_5655872_4 Pectinesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 490.0
HKD1_k127_5655872_5 amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 468.0
HKD1_k127_5655872_6 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 423.0
HKD1_k127_5655872_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
HKD1_k127_5655872_8 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 385.0
HKD1_k127_5655872_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 336.0
HKD1_k127_5671224_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 375.0
HKD1_k127_5671224_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 292.0
HKD1_k127_5671224_2 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000002963 213.0
HKD1_k127_5686240_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.124e-294 924.0
HKD1_k127_5686240_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 4.891e-210 668.0
HKD1_k127_5686240_10 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 421.0
HKD1_k127_5686240_11 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 381.0
HKD1_k127_5686240_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 347.0
HKD1_k127_5686240_13 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 325.0
HKD1_k127_5686240_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 323.0
HKD1_k127_5686240_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 307.0
HKD1_k127_5686240_16 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001677 283.0
HKD1_k127_5686240_17 Domain of unknown function (DUF1835) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004874 242.0
HKD1_k127_5686240_18 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000007662 218.0
HKD1_k127_5686240_19 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000006368 217.0
HKD1_k127_5686240_2 PFAM Alcohol dehydrogenase GroES-like - - - 1.587e-206 646.0
HKD1_k127_5686240_20 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000002297 201.0
HKD1_k127_5686240_21 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000003252 191.0
HKD1_k127_5686240_22 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000015 151.0
HKD1_k127_5686240_23 Domain of unknown function (DUF4142) - - - 0.000000000000000000000000007361 119.0
HKD1_k127_5686240_24 membrane K08995 - - 0.0000000000001871 80.0
HKD1_k127_5686240_25 23S rRNA-intervening sequence protein - - - 0.000000000008962 70.0
HKD1_k127_5686240_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 605.0
HKD1_k127_5686240_4 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 491.0
HKD1_k127_5686240_5 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 486.0
HKD1_k127_5686240_6 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 427.0
HKD1_k127_5686240_7 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 426.0
HKD1_k127_5686240_8 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 415.0
HKD1_k127_5686240_9 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 400.0
HKD1_k127_5689289_0 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 565.0
HKD1_k127_5689289_1 NmrA-like family K07118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 315.0
HKD1_k127_5689289_3 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000006172 152.0
HKD1_k127_5689289_4 PFAM Rieske 2Fe-2S domain K05710 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000007063 115.0
HKD1_k127_5689289_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000001371 114.0
HKD1_k127_5718688_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 392.0
HKD1_k127_5718688_1 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000324 147.0
HKD1_k127_5718688_2 - - - - 0.00000006579 54.0
HKD1_k127_5780819_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 508.0
HKD1_k127_5780819_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 394.0
HKD1_k127_5780819_12 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000001897 159.0
HKD1_k127_5780819_13 Fic/DOC family K07341 - - 0.00000000000000000000000000000000000000002287 157.0
HKD1_k127_5780819_14 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000000000000000000000000000000000002318 158.0
HKD1_k127_5780819_15 Thioesterase - - - 0.00000000000000000000000000000000000000005023 160.0
HKD1_k127_5780819_16 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000001374 152.0
HKD1_k127_5780819_17 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000003051 153.0
HKD1_k127_5780819_18 OsmC-like protein - - - 0.00000000000000000000000000000000000001195 148.0
HKD1_k127_5780819_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 363.0
HKD1_k127_5780819_20 ASCH - - - 0.0000000000000000000000000000000001373 136.0
HKD1_k127_5780819_21 - - - - 0.000000000000000000000000000000001069 134.0
HKD1_k127_5780819_22 metal-dependent membrane protease - - - 0.000000000000000000000000000000001393 141.0
HKD1_k127_5780819_23 DinB family - - - 0.000000000000000000000000000000004507 134.0
HKD1_k127_5780819_24 transferase activity, transferring acyl groups K03824 - - 0.00000000000000000000000000000003874 137.0
HKD1_k127_5780819_25 - - - - 0.000000000000000000000000000566 114.0
HKD1_k127_5780819_26 Phospholipid methyltransferase - - - 0.0000000000000000000000008522 111.0
HKD1_k127_5780819_27 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000001321 108.0
HKD1_k127_5780819_28 - - - - 0.00000000000000000000168 102.0
HKD1_k127_5780819_29 DinB family - - - 0.00000000000000000006145 100.0
HKD1_k127_5780819_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 372.0
HKD1_k127_5780819_30 RNA polymerase sigma factor K03088 - - 0.00000000000000001447 89.0
HKD1_k127_5780819_31 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000005168 80.0
HKD1_k127_5780819_32 COG0671 Membrane-associated phospholipid phosphatase - - - 0.00000000000000009887 91.0
HKD1_k127_5780819_33 - - - - 0.0000000000000001323 86.0
HKD1_k127_5780819_34 RibD C-terminal domain - - - 0.0000000000000002966 78.0
HKD1_k127_5780819_35 DinB superfamily - - - 0.00000000000001651 81.0
HKD1_k127_5780819_37 Protein of unknown function (DUF3795) - - - 0.0000000000002683 76.0
HKD1_k127_5780819_38 Protein of unknown function (DUF3995) - - - 0.0000000000006334 76.0
HKD1_k127_5780819_39 SnoaL-like domain - - - 0.0000000000008622 74.0
HKD1_k127_5780819_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002955 226.0
HKD1_k127_5780819_40 NnrU protein - - - 0.000000000001043 74.0
HKD1_k127_5780819_41 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.000000000001108 69.0
HKD1_k127_5780819_42 translation initiation factor activity K06996 - - 0.0000000002031 71.0
HKD1_k127_5780819_43 - - - - 0.0000006943 58.0
HKD1_k127_5780819_44 - - - - 0.0002762 52.0
HKD1_k127_5780819_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000006402 222.0
HKD1_k127_5780819_6 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000958 209.0
HKD1_k127_5780819_7 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000034 200.0
HKD1_k127_5780819_8 methyltransferase activity K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000009785 204.0
HKD1_k127_5780819_9 - - - - 0.00000000000000000000000000000000000000000000001904 176.0
HKD1_k127_5924128_0 GMC oxidoreductase - - - 1.529e-252 788.0
HKD1_k127_5924128_1 Prolyl oligopeptidase - - - 1.036e-195 629.0
HKD1_k127_5924128_10 PFAM membrane protein of K08972 - - 0.000000000000000000000000002585 114.0
HKD1_k127_5924128_11 - - - - 0.00000001204 62.0
HKD1_k127_5924128_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 424.0
HKD1_k127_5924128_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 428.0
HKD1_k127_5924128_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 372.0
HKD1_k127_5924128_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 329.0
HKD1_k127_5924128_6 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000007244 223.0
HKD1_k127_5924128_7 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000001453 195.0
HKD1_k127_5924128_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000592 171.0
HKD1_k127_5924128_9 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000000001312 128.0
HKD1_k127_593334_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 434.0
HKD1_k127_593334_1 - - - - 0.00000000000000000000000000000000000000000000001701 188.0
HKD1_k127_593334_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000004658 126.0
HKD1_k127_6037220_0 beta-glucosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 464.0
HKD1_k127_6037220_1 Flavodoxin-like fold K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004294 266.0
HKD1_k127_6037220_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000000001014 230.0
HKD1_k127_6037220_3 - - - - 0.00000000000000000000000000000000000000000000000000004833 196.0
HKD1_k127_6037220_4 - - - - 0.0000000000000375 79.0
HKD1_k127_6037220_6 - - - - 0.0009153 44.0
HKD1_k127_6038734_0 Peptidase M14, carboxypeptidase A - - - 0.0 1400.0
HKD1_k127_6038734_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1242.0
HKD1_k127_6038734_10 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 346.0
HKD1_k127_6038734_11 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 308.0
HKD1_k127_6038734_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HKD1_k127_6038734_13 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000004191 245.0
HKD1_k127_6038734_14 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000001476 203.0
HKD1_k127_6038734_15 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000114 180.0
HKD1_k127_6038734_16 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000168 153.0
HKD1_k127_6038734_17 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000003413 111.0
HKD1_k127_6038734_19 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000001934 95.0
HKD1_k127_6038734_2 Belongs to the ClpA ClpB family K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1174.0
HKD1_k127_6038734_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000007361 103.0
HKD1_k127_6038734_21 COGs COG2929 conserved K09803 - - 0.0000000000000002873 83.0
HKD1_k127_6038734_22 methyltransferase activity - - - 0.0000000000000003079 86.0
HKD1_k127_6038734_24 Carboxypeptidase regulatory-like domain - - - 0.0005817 44.0
HKD1_k127_6038734_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 2.005e-280 879.0
HKD1_k127_6038734_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.22e-226 716.0
HKD1_k127_6038734_5 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 592.0
HKD1_k127_6038734_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
HKD1_k127_6038734_7 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 408.0
HKD1_k127_6038734_8 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 364.0
HKD1_k127_6038734_9 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
HKD1_k127_6040436_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 405.0
HKD1_k127_6040436_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000003832 248.0
HKD1_k127_6040436_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000009551 166.0
HKD1_k127_6040436_3 T4-like virus tail tube protein gp19 - - - 0.0000000000000001869 81.0
HKD1_k127_6040436_4 Psort location CytoplasmicMembrane, score K02237 - - 0.0000000000000004392 85.0
HKD1_k127_6040436_5 beta-fructofuranosidase activity - - - 0.00001498 54.0
HKD1_k127_6040436_6 Type II transport protein GspH K08084 - - 0.0003244 53.0
HKD1_k127_6042117_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 611.0
HKD1_k127_6059164_0 Oligopeptide transporter OPT - - - 2.502e-242 768.0
HKD1_k127_6059164_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 576.0
HKD1_k127_6059164_2 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 453.0
HKD1_k127_6059164_3 Histidine kinase internal region K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004641 269.0
HKD1_k127_6059164_4 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
HKD1_k127_6059164_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000001753 212.0
HKD1_k127_6059164_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000001114 205.0
HKD1_k127_6059164_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000001352 180.0
HKD1_k127_6059164_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000002057 157.0
HKD1_k127_6069613_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.015e-276 853.0
HKD1_k127_6069613_1 Putative zincin peptidase - - - 0.000002298 56.0
HKD1_k127_6089063_0 Major facilitator Superfamily K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 516.0
HKD1_k127_6089063_1 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
HKD1_k127_6089063_10 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001257 208.0
HKD1_k127_6089063_11 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000734 205.0
HKD1_k127_6089063_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000003107 177.0
HKD1_k127_6089063_13 DinB family - - - 0.00000000000000000000000000000000000000000002566 173.0
HKD1_k127_6089063_14 EF-hand domain pair - - - 0.00000008402 61.0
HKD1_k127_6089063_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0003231 53.0
HKD1_k127_6089063_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 473.0
HKD1_k127_6089063_3 PFAM Glycosyl transferase, group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 444.0
HKD1_k127_6089063_4 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 423.0
HKD1_k127_6089063_5 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 407.0
HKD1_k127_6089063_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 363.0
HKD1_k127_6089063_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 346.0
HKD1_k127_6089063_8 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000372 266.0
HKD1_k127_6089063_9 deacetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000009718 211.0
HKD1_k127_6097591_0 Fibronectin type III-like domain K05349 - 3.2.1.21 1.945e-308 970.0
HKD1_k127_6097591_1 Tricorn protease homolog K08676 - - 1.688e-212 665.0
HKD1_k127_6097591_2 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000008859 250.0
HKD1_k127_6097591_3 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 262.0
HKD1_k127_6097591_4 - - - - 0.0000005465 61.0
HKD1_k127_6101451_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1177.0
HKD1_k127_6101451_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 438.0
HKD1_k127_6101451_10 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 291.0
HKD1_k127_6101451_11 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 285.0
HKD1_k127_6101451_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 300.0
HKD1_k127_6101451_13 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
HKD1_k127_6101451_14 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002822 264.0
HKD1_k127_6101451_15 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
HKD1_k127_6101451_16 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005852 253.0
HKD1_k127_6101451_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000001732 234.0
HKD1_k127_6101451_18 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000004351 245.0
HKD1_k127_6101451_19 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000276 235.0
HKD1_k127_6101451_2 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 430.0
HKD1_k127_6101451_20 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000006552 212.0
HKD1_k127_6101451_21 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000001156 183.0
HKD1_k127_6101451_22 - - - - 0.000000000000000000000000000000009536 133.0
HKD1_k127_6101451_23 Phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000001539 123.0
HKD1_k127_6101451_24 recA bacterial DNA recombination protein - - - 0.0000000000000000000003974 105.0
HKD1_k127_6101451_25 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000332 103.0
HKD1_k127_6101451_26 - - - - 0.0000000000000000003989 92.0
HKD1_k127_6101451_27 Domain of unknown function (DUF4956) - - - 0.000000000000006788 85.0
HKD1_k127_6101451_29 von Willebrand factor, type A K07114 - - 0.00000007641 66.0
HKD1_k127_6101451_3 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 400.0
HKD1_k127_6101451_30 Disulphide bond corrector protein DsbC - - - 0.0000003208 58.0
HKD1_k127_6101451_31 PFAM CHAD domain containing protein - - - 0.000004764 58.0
HKD1_k127_6101451_32 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00002823 53.0
HKD1_k127_6101451_33 Calcineurin-like phosphoesterase - - - 0.00004116 48.0
HKD1_k127_6101451_34 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000738 50.0
HKD1_k127_6101451_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 410.0
HKD1_k127_6101451_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 368.0
HKD1_k127_6101451_6 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
HKD1_k127_6101451_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 359.0
HKD1_k127_6101451_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 325.0
HKD1_k127_6101451_9 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 316.0
HKD1_k127_6102279_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 514.0
HKD1_k127_6102279_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 473.0
HKD1_k127_6102279_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 453.0
HKD1_k127_6102279_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000007604 172.0
HKD1_k127_6102279_4 PFAM Stress-induced bacterial acidophilic repeat motif K06884 - - 0.00000000000002041 79.0
HKD1_k127_6103728_0 Carbamoyltransferase C-terminus K00612 - - 4.675e-225 715.0
HKD1_k127_6103728_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 386.0
HKD1_k127_6103728_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000352 237.0
HKD1_k127_6103728_11 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000008551 228.0
HKD1_k127_6103728_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
HKD1_k127_6103728_13 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000001244 213.0
HKD1_k127_6103728_14 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000334 182.0
HKD1_k127_6103728_15 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000005508 177.0
HKD1_k127_6103728_16 glucosamine-1-phosphate N-acetyltransferase activity K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000005815 149.0
HKD1_k127_6103728_17 slime layer polysaccharide biosynthetic process K06871,K16710 - - 0.000000000000000000000000000000000007505 151.0
HKD1_k127_6103728_18 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000002015 143.0
HKD1_k127_6103728_19 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000003106 136.0
HKD1_k127_6103728_2 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
HKD1_k127_6103728_20 Methyltransferase domain - - - 0.00000000000000000000000000004949 126.0
HKD1_k127_6103728_21 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000003253 112.0
HKD1_k127_6103728_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000003505 118.0
HKD1_k127_6103728_23 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000008148 113.0
HKD1_k127_6103728_24 Methyltransferase domain - - - 0.0000000000000000000006059 105.0
HKD1_k127_6103728_25 lipolytic protein G-D-S-L family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000002869 93.0
HKD1_k127_6103728_26 domain protein - - - 0.000000000000001068 89.0
HKD1_k127_6103728_27 GDSL-like Lipase/Acylhydrolase - - - 0.000000000009826 76.0
HKD1_k127_6103728_28 - - - - 0.00000000001034 77.0
HKD1_k127_6103728_29 glycosyl transferase family 2 K07011 - - 0.0000000003935 72.0
HKD1_k127_6103728_3 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 337.0
HKD1_k127_6103728_30 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001151 72.0
HKD1_k127_6103728_31 Lysylphosphatidylglycerol synthase TM region - - - 0.0000006961 61.0
HKD1_k127_6103728_32 - - - - 0.000004681 57.0
HKD1_k127_6103728_33 Uncharacterized membrane protein (DUF2298) - - - 0.00008699 56.0
HKD1_k127_6103728_4 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 339.0
HKD1_k127_6103728_5 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 300.0
HKD1_k127_6103728_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008962 265.0
HKD1_k127_6103728_7 transferase activity, transferring glycosyl groups K11740,K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002509 271.0
HKD1_k127_6103728_8 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003633 261.0
HKD1_k127_6103728_9 O-acyltransferase activity K00633 - 2.3.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001858 241.0
HKD1_k127_6125987_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.68e-293 919.0
HKD1_k127_6125987_1 peptidase K07386 - - 8.342e-266 841.0
HKD1_k127_6125987_10 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 417.0
HKD1_k127_6125987_11 Sigma-54 interaction domain K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 405.0
HKD1_k127_6125987_12 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 364.0
HKD1_k127_6125987_13 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 370.0
HKD1_k127_6125987_14 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 351.0
HKD1_k127_6125987_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
HKD1_k127_6125987_16 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 330.0
HKD1_k127_6125987_17 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 325.0
HKD1_k127_6125987_18 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 324.0
HKD1_k127_6125987_19 ATPase activity K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 302.0
HKD1_k127_6125987_2 Asparagine synthase K01953 - 6.3.5.4 4.32e-224 713.0
HKD1_k127_6125987_20 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 297.0
HKD1_k127_6125987_21 Serine aminopeptidase, S33 K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 289.0
HKD1_k127_6125987_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009159 285.0
HKD1_k127_6125987_23 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000003771 259.0
HKD1_k127_6125987_24 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007394 254.0
HKD1_k127_6125987_25 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002674 258.0
HKD1_k127_6125987_26 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006232 249.0
HKD1_k127_6125987_27 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000008758 215.0
HKD1_k127_6125987_28 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000007574 213.0
HKD1_k127_6125987_29 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002509 209.0
HKD1_k127_6125987_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 1.23e-215 678.0
HKD1_k127_6125987_30 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000007078 198.0
HKD1_k127_6125987_31 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000002247 208.0
HKD1_k127_6125987_32 Uncharacterised protein family UPF0052 - - - 0.00000000000000000000000000000000000000000000000000004237 201.0
HKD1_k127_6125987_33 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000114 195.0
HKD1_k127_6125987_34 - - - - 0.000000000000000000000000000000000000000000000104 177.0
HKD1_k127_6125987_35 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000001783 176.0
HKD1_k127_6125987_36 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000001021 168.0
HKD1_k127_6125987_37 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000003023 163.0
HKD1_k127_6125987_38 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000003597 177.0
HKD1_k127_6125987_39 DinB family - - - 0.000000000000000000000000000000000000000006179 161.0
HKD1_k127_6125987_4 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 574.0
HKD1_k127_6125987_40 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000001504 160.0
HKD1_k127_6125987_41 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000009167 145.0
HKD1_k127_6125987_42 membrane - - - 0.000000000000000000000000000000000000229 149.0
HKD1_k127_6125987_43 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.0000000000000000000000000000000009487 151.0
HKD1_k127_6125987_44 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000003278 137.0
HKD1_k127_6125987_45 4Fe-4S binding domain - - - 0.00000000000000000000000000000002356 127.0
HKD1_k127_6125987_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000001327 126.0
HKD1_k127_6125987_47 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000001031 120.0
HKD1_k127_6125987_48 Methanol dehydrogenase K06872 - - 0.00000000000000000000000000001964 129.0
HKD1_k127_6125987_49 outer membrane efflux protein - - - 0.00000000000000000000000000003167 134.0
HKD1_k127_6125987_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 502.0
HKD1_k127_6125987_50 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000004478 128.0
HKD1_k127_6125987_51 transcriptional regulator - - - 0.000000000000000000002971 103.0
HKD1_k127_6125987_52 Phosphopantetheine attachment site - - - 0.000000000000000000008616 96.0
HKD1_k127_6125987_53 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000001393 103.0
HKD1_k127_6125987_54 nucleotidyltransferase activity - - - 0.00000000000000000011 102.0
HKD1_k127_6125987_55 - - - - 0.0000000000000000004014 92.0
HKD1_k127_6125987_56 Transferase hexapeptide repeat - - - 0.00000000000000001027 93.0
HKD1_k127_6125987_57 helix_turn_helix isocitrate lyase regulation K13641 - - 0.0000000000000001675 90.0
HKD1_k127_6125987_58 - - - - 0.0000000000000002727 82.0
HKD1_k127_6125987_59 General stress protein K06884 - - 0.000000000000004226 78.0
HKD1_k127_6125987_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 501.0
HKD1_k127_6125987_60 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000002243 78.0
HKD1_k127_6125987_61 - - - - 0.0000000000002181 82.0
HKD1_k127_6125987_63 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001255 62.0
HKD1_k127_6125987_64 Peptidase m28 - - - 0.000000122 64.0
HKD1_k127_6125987_65 AntiSigma factor - - - 0.0000004783 60.0
HKD1_k127_6125987_66 - - - - 0.0000005363 57.0
HKD1_k127_6125987_67 aspartic-type endopeptidase activity K06985,K07272,K20543,K21007 - - 0.000001702 61.0
HKD1_k127_6125987_68 - - - - 0.000009363 58.0
HKD1_k127_6125987_69 Hexapeptide repeat of succinyl-transferase - - - 0.00002252 55.0
HKD1_k127_6125987_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 483.0
HKD1_k127_6125987_70 - - - - 0.0002864 53.0
HKD1_k127_6125987_71 cellulase activity - - - 0.0002978 53.0
HKD1_k127_6125987_8 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 429.0
HKD1_k127_6125987_9 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 430.0
HKD1_k127_6127159_0 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 6.678e-270 858.0
HKD1_k127_6127159_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 4.975e-266 846.0
HKD1_k127_6127159_10 - - - - 0.0009439 51.0
HKD1_k127_6127159_2 Carbohydrate family 9 binding domain-like - - - 8.01e-197 643.0
HKD1_k127_6127159_3 PFAM Dynamin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 515.0
HKD1_k127_6127159_4 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 299.0
HKD1_k127_6127159_5 SMART metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000002591 191.0
HKD1_k127_6127159_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000001045 166.0
HKD1_k127_6127159_7 antisigma factor binding - - - 0.000000000003898 76.0
HKD1_k127_6127159_8 fatty acid desaturase - - - 0.000000000005535 76.0
HKD1_k127_6127159_9 - - - - 0.000004704 52.0
HKD1_k127_6128161_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1269.0
HKD1_k127_6128161_1 imidazolonepropionase activity K00466 - 1.13.12.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 616.0
HKD1_k127_6128161_2 Pfam Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 376.0
HKD1_k127_6128161_3 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002418 264.0
HKD1_k127_6128161_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000001279 146.0
HKD1_k127_6128161_5 Carboxypeptidase regulatory-like domain - - - 0.000000004012 69.0
HKD1_k127_6128161_6 Amidohydrolase family - - - 0.0000003583 51.0
HKD1_k127_6128161_7 Polymer-forming cytoskeletal - - - 0.0004318 53.0
HKD1_k127_6177581_0 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 454.0
HKD1_k127_6177600_0 Acetyl-CoA carboxylase, central region - - - 0.0 1963.0
HKD1_k127_6177600_1 Ketoacyl-synthetase C-terminal extension - - - 0.0 1069.0
HKD1_k127_6177600_2 MacB-like periplasmic core domain - - - 2.839e-226 729.0
HKD1_k127_6177600_3 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 511.0
HKD1_k127_6177600_4 Enoyl-(Acyl carrier protein) reductase K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 310.0
HKD1_k127_6177600_5 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000000000000005843 148.0
HKD1_k127_6177600_6 Tyrosine phosphatase family - - - 0.0000000000000000000001027 106.0
HKD1_k127_6178072_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 411.0
HKD1_k127_6178072_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004324 288.0
HKD1_k127_6179735_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 318.0
HKD1_k127_6179735_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000006422 186.0
HKD1_k127_6184199_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.806e-269 850.0
HKD1_k127_6184199_1 Domain of unknown function (DUF362) - - - 2.605e-220 689.0
HKD1_k127_6184199_10 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 458.0
HKD1_k127_6184199_11 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 455.0
HKD1_k127_6184199_12 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 424.0
HKD1_k127_6184199_13 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 409.0
HKD1_k127_6184199_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 409.0
HKD1_k127_6184199_15 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 364.0
HKD1_k127_6184199_16 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 343.0
HKD1_k127_6184199_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
HKD1_k127_6184199_18 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 344.0
HKD1_k127_6184199_19 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 333.0
HKD1_k127_6184199_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.256e-216 684.0
HKD1_k127_6184199_20 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 314.0
HKD1_k127_6184199_21 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 301.0
HKD1_k127_6184199_22 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001863 293.0
HKD1_k127_6184199_23 Caenorhabditis protein of unknown function, DUF268 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 250.0
HKD1_k127_6184199_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
HKD1_k127_6184199_25 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000001356 224.0
HKD1_k127_6184199_26 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000004143 225.0
HKD1_k127_6184199_27 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000002202 186.0
HKD1_k127_6184199_28 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000002548 148.0
HKD1_k127_6184199_29 Phosphoesterase K07098 - - 0.0000000000000000000000000000000000001359 153.0
HKD1_k127_6184199_3 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 595.0
HKD1_k127_6184199_30 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000004691 119.0
HKD1_k127_6184199_31 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000183 100.0
HKD1_k127_6184199_32 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000002344 101.0
HKD1_k127_6184199_33 - - - - 0.0000000000000000001333 93.0
HKD1_k127_6184199_34 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000001281 59.0
HKD1_k127_6184199_35 Peptidase M56 - - - 0.000000001341 70.0
HKD1_k127_6184199_36 - - - - 0.000000237 53.0
HKD1_k127_6184199_37 PBS lyase HEAT-like repeat - - - 0.0001032 55.0
HKD1_k127_6184199_38 Probably involved in nutrient binding - - - 0.0005975 53.0
HKD1_k127_6184199_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 592.0
HKD1_k127_6184199_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 567.0
HKD1_k127_6184199_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 538.0
HKD1_k127_6184199_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 518.0
HKD1_k127_6184199_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 486.0
HKD1_k127_6184199_9 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 468.0
HKD1_k127_6205341_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 590.0
HKD1_k127_6205341_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 548.0
HKD1_k127_6205341_10 - - - - 0.00000000000000000000000000000000000000000000000001484 183.0
HKD1_k127_6205341_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000003812 179.0
HKD1_k127_6205341_14 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000004018 183.0
HKD1_k127_6205341_15 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000001055 162.0
HKD1_k127_6205341_16 Membrane - - - 0.0000000000000000000000000000006076 127.0
HKD1_k127_6205341_17 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000001538 124.0
HKD1_k127_6205341_18 WG containing repeat - - - 0.00000000000000000000000004191 115.0
HKD1_k127_6205341_19 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000001053 111.0
HKD1_k127_6205341_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 465.0
HKD1_k127_6205341_20 - - - - 0.000000000000000000000003336 108.0
HKD1_k127_6205341_21 - - - - 0.000000000002306 76.0
HKD1_k127_6205341_22 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000002393 73.0
HKD1_k127_6205341_23 translation initiation factor activity K06996 - - 0.0000000003068 64.0
HKD1_k127_6205341_24 KWG Leptospira - - - 0.0000000005572 66.0
HKD1_k127_6205341_25 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000004976 68.0
HKD1_k127_6205341_26 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.0000004715 59.0
HKD1_k127_6205341_27 Baseplate J-like protein - - - 0.000004897 59.0
HKD1_k127_6205341_28 TIR domain - - - 0.00003207 54.0
HKD1_k127_6205341_29 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0003248 47.0
HKD1_k127_6205341_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 413.0
HKD1_k127_6205341_4 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
HKD1_k127_6205341_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001087 277.0
HKD1_k127_6205341_6 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002049 255.0
HKD1_k127_6205341_7 Signal Transduction Histidine Kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001398 249.0
HKD1_k127_6205341_8 s cog2930 - - - 0.000000000000000000000000000000000000000000000000000000000000001584 230.0
HKD1_k127_6205341_9 KWG Leptospira - - - 0.0000000000000000000000000000000000000000000000000000000000003381 225.0
HKD1_k127_6210785_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 511.0
HKD1_k127_6210785_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 440.0
HKD1_k127_6210785_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 424.0
HKD1_k127_6210785_3 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000003878 81.0
HKD1_k127_6238183_0 Peptidase M14, carboxypeptidase A - - - 0.0 1102.0
HKD1_k127_6238183_1 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 523.0
HKD1_k127_6238183_2 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 369.0
HKD1_k127_6238183_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 255.0
HKD1_k127_6238183_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001615 261.0
HKD1_k127_6238183_5 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000203 230.0
HKD1_k127_6238183_6 oxidoreductase activity - - - 0.0000000000000000000000000006345 130.0
HKD1_k127_6238183_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000009351 97.0
HKD1_k127_6319168_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000001715 138.0
HKD1_k127_6319168_1 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 0.0000000000003057 83.0
HKD1_k127_6319168_2 antisigma factor binding K04749 - - 0.000000004514 64.0
HKD1_k127_6321856_0 cellulose binding - - - 2.547e-301 967.0
HKD1_k127_6321856_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 508.0
HKD1_k127_6321856_10 - - - - 0.000000000000000000000000000000004648 131.0
HKD1_k127_6321856_11 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000001525 117.0
HKD1_k127_6321856_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000002976 116.0
HKD1_k127_6321856_13 Protein of unknown function (DUF504) - - - 0.00000000000000006994 83.0
HKD1_k127_6321856_14 COG0745 Response regulators consisting of a CheY-like - - - 0.0000000000000001309 91.0
HKD1_k127_6321856_15 Cold shock protein domain - - - 0.0000000000000002521 80.0
HKD1_k127_6321856_16 GDSL-like Lipase/Acylhydrolase - - - 0.000008092 57.0
HKD1_k127_6321856_2 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 440.0
HKD1_k127_6321856_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 420.0
HKD1_k127_6321856_4 NADP Oxidoreductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 350.0
HKD1_k127_6321856_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 359.0
HKD1_k127_6321856_6 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 333.0
HKD1_k127_6321856_7 4Fe-4S binding domain K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 304.0
HKD1_k127_6321856_8 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004108 251.0
HKD1_k127_6321856_9 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000003406 167.0
HKD1_k127_6322970_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 6.16e-234 735.0
HKD1_k127_6322970_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 321.0
HKD1_k127_6322970_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000828 250.0
HKD1_k127_6322970_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000001391 204.0
HKD1_k127_6322970_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000004711 164.0
HKD1_k127_6322970_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000001835 136.0
HKD1_k127_6322970_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000001901 86.0
HKD1_k127_6322970_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000007536 74.0
HKD1_k127_6322970_8 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.0000001155 56.0
HKD1_k127_6322970_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00004131 49.0
HKD1_k127_6332978_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 509.0
HKD1_k127_6332978_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
HKD1_k127_6332978_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
HKD1_k127_6332978_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001441 273.0
HKD1_k127_6332978_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000008848 171.0
HKD1_k127_6332978_5 Leucine carboxyl methyltransferase - - - 0.00000000000000007621 83.0
HKD1_k127_6336692_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 3.242e-313 971.0
HKD1_k127_6336692_1 Electron transfer flavoprotein-ubiquinone K00311 - 1.5.5.1 1.712e-236 747.0
HKD1_k127_6336692_10 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 323.0
HKD1_k127_6336692_11 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 293.0
HKD1_k127_6336692_12 D-arabinono-1,4-lactone oxidase K00103 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016491,GO:0016627,GO:0016632,GO:0019752,GO:0019852,GO:0019853,GO:0030312,GO:0042364,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046364,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0080049,GO:1901576 1.1.3.8 0.00000000000000000000000000000000000000000000000000000000000001276 232.0
HKD1_k127_6336692_13 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000008786 221.0
HKD1_k127_6336692_14 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000001013 216.0
HKD1_k127_6336692_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000006494 188.0
HKD1_k127_6336692_16 arsR family - - - 0.000000000000000000000000002527 119.0
HKD1_k127_6336692_17 Cupin 2, conserved barrel - - - 0.00000000000000000000000001413 113.0
HKD1_k127_6336692_18 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000007772 87.0
HKD1_k127_6336692_19 SnoaL-like polyketide cyclase - - - 0.000000000004355 72.0
HKD1_k127_6336692_2 Amidohydrolase family K06015 - 3.5.1.81 1.398e-211 672.0
HKD1_k127_6336692_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 550.0
HKD1_k127_6336692_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 541.0
HKD1_k127_6336692_5 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 468.0
HKD1_k127_6336692_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 463.0
HKD1_k127_6336692_7 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 439.0
HKD1_k127_6336692_8 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 381.0
HKD1_k127_6336692_9 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 364.0
HKD1_k127_6339903_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 599.0
HKD1_k127_6339903_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 554.0
HKD1_k127_6339903_2 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 356.0
HKD1_k127_6339903_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
HKD1_k127_6339903_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 300.0
HKD1_k127_6339903_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007449 276.0
HKD1_k127_6339903_6 AAA domain - - - 0.00000000000000000000000000000000004569 144.0
HKD1_k127_6339903_7 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.0000000000000000000000000000000000811 150.0
HKD1_k127_6339903_8 Two component regulator propeller - - - 0.0000002111 63.0
HKD1_k127_639269_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 380.0
HKD1_k127_639269_1 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 344.0
HKD1_k127_639269_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000003731 241.0
HKD1_k127_639269_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000007274 201.0
HKD1_k127_639269_4 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000001147 130.0
HKD1_k127_639269_5 phosphorelay signal transduction system K14987 - - 0.0000000000000000000000000001076 120.0
HKD1_k127_639330_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1020.0
HKD1_k127_639330_1 BON domain K04065 - - 0.000000000000000000000000000000000000000000000000000000000008756 216.0
HKD1_k127_639330_2 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000004248 119.0
HKD1_k127_639330_3 Protein of unknown function (DUF1269) - - - 0.0000000000000000000006421 104.0
HKD1_k127_639330_4 excinuclease ABC activity K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000302 56.0
HKD1_k127_6400730_0 Acyl transferase domain - - - 0.0 2006.0
HKD1_k127_6400730_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1251.0
HKD1_k127_6400730_10 Pyridoxal-phosphate dependent enzyme - - - 2.225e-208 659.0
HKD1_k127_6400730_11 Amidohydrolase family K06015 - 3.5.1.81 3.503e-196 628.0
HKD1_k127_6400730_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 567.0
HKD1_k127_6400730_13 COG0044 Dihydroorotase and related cyclic amidohydrolases K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 531.0
HKD1_k127_6400730_14 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 513.0
HKD1_k127_6400730_15 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 503.0
HKD1_k127_6400730_16 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 498.0
HKD1_k127_6400730_17 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 511.0
HKD1_k127_6400730_18 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 462.0
HKD1_k127_6400730_19 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 451.0
HKD1_k127_6400730_2 Carboxypeptidase regulatory-like domain - - - 0.0 1116.0
HKD1_k127_6400730_20 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 432.0
HKD1_k127_6400730_21 fatty acid beta-oxidation using acyl-CoA dehydrogenase K00248,K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006575,GO:0006577,GO:0006579,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009437,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0034641,GO:0036094,GO:0042219,GO:0042413,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:0097164,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 421.0
HKD1_k127_6400730_22 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 394.0
HKD1_k127_6400730_23 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 393.0
HKD1_k127_6400730_24 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 387.0
HKD1_k127_6400730_25 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 385.0
HKD1_k127_6400730_26 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 367.0
HKD1_k127_6400730_27 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 359.0
HKD1_k127_6400730_28 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 354.0
HKD1_k127_6400730_29 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 341.0
HKD1_k127_6400730_3 Cysteine-rich domain - - - 3.354e-289 902.0
HKD1_k127_6400730_30 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 305.0
HKD1_k127_6400730_31 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
HKD1_k127_6400730_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002918 270.0
HKD1_k127_6400730_33 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005517 265.0
HKD1_k127_6400730_34 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
HKD1_k127_6400730_35 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
HKD1_k127_6400730_36 Adventurous gliding motility protein R - - - 0.000000000000000000000000000000000000000000000000000000003039 213.0
HKD1_k127_6400730_37 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000007679 205.0
HKD1_k127_6400730_38 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000005071 186.0
HKD1_k127_6400730_39 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000127 177.0
HKD1_k127_6400730_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.155e-286 889.0
HKD1_k127_6400730_40 YCII-related domain - - - 0.00000000000000000000000000000000000000000000678 168.0
HKD1_k127_6400730_41 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000004222 182.0
HKD1_k127_6400730_42 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000003816 147.0
HKD1_k127_6400730_43 - - - - 0.00000000000000000000000000000000002567 151.0
HKD1_k127_6400730_44 GrpB protein - - - 0.00000000000000000000000000000000005153 140.0
HKD1_k127_6400730_45 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000006328 132.0
HKD1_k127_6400730_47 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.00000000000000000000000002778 124.0
HKD1_k127_6400730_48 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000004894 111.0
HKD1_k127_6400730_49 von Willebrand factor, type A - - - 0.00000000000000000002026 103.0
HKD1_k127_6400730_5 lysine biosynthetic process via aminoadipic acid - - - 1.396e-268 844.0
HKD1_k127_6400730_51 Polyhydroxyalkanoate granule-associated protein - - - 0.000000000000000001937 89.0
HKD1_k127_6400730_52 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000408 88.0
HKD1_k127_6400730_53 Diacylglycerol kinase K19302 - 3.6.1.27 0.000000000000000007567 91.0
HKD1_k127_6400730_54 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000005542 92.0
HKD1_k127_6400730_56 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000001872 67.0
HKD1_k127_6400730_57 - - - - 0.0000000003066 74.0
HKD1_k127_6400730_6 oxidoreductase activity - - - 5.139e-257 811.0
HKD1_k127_6400730_7 COG3119 Arylsulfatase A and related enzymes - - - 9.703e-254 797.0
HKD1_k127_6400730_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 3.806e-246 775.0
HKD1_k127_6400730_9 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.592e-220 694.0
HKD1_k127_6404553_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 4.376e-269 844.0
HKD1_k127_6404553_1 Peptidase dimerisation domain - - - 9.112e-229 715.0
HKD1_k127_6404553_10 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000009933 200.0
HKD1_k127_6404553_11 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000000000000000000000000000000000000000000000009667 195.0
HKD1_k127_6404553_12 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.00000000000000000000000000000000000000000000001542 172.0
HKD1_k127_6404553_13 Penicillinase repressor - - - 0.000000000000000000000000000005751 123.0
HKD1_k127_6404553_14 - - - - 0.000000000000000000000000002451 115.0
HKD1_k127_6404553_15 Protein of unknown function (DUF3124) - - - 0.00000000000000000001757 97.0
HKD1_k127_6404553_16 - - - - 0.000000000000002829 80.0
HKD1_k127_6404553_17 thiolester hydrolase activity K06889 - - 0.0000002702 63.0
HKD1_k127_6404553_18 Acetyltransferase K00633,K00661 - 2.3.1.18,2.3.1.79 0.00009728 45.0
HKD1_k127_6404553_19 - - - - 0.0003507 45.0
HKD1_k127_6404553_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 506.0
HKD1_k127_6404553_3 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HKD1_k127_6404553_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 351.0
HKD1_k127_6404553_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 346.0
HKD1_k127_6404553_6 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 277.0
HKD1_k127_6404553_7 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002992 276.0
HKD1_k127_6404553_8 light absorption - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 269.0
HKD1_k127_6404553_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000007647 234.0
HKD1_k127_6431794_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000006855 175.0
HKD1_k127_6431794_1 Glycine zipper 2TM domain - - - 0.0000000000000000000005831 104.0
HKD1_k127_6469932_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1162.0
HKD1_k127_6469932_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 5.769e-291 915.0
HKD1_k127_6469932_10 chaperone-mediated protein folding - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 291.0
HKD1_k127_6469932_11 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
HKD1_k127_6469932_12 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009134 280.0
HKD1_k127_6469932_13 pectinesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001791 267.0
HKD1_k127_6469932_14 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000000000000000000005513 203.0
HKD1_k127_6469932_15 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000001943 200.0
HKD1_k127_6469932_16 Lipase (class 3) K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000002264 207.0
HKD1_k127_6469932_17 Ferric uptake regulator family K22297 - - 0.000000000000000000000000000000000000000000000000000005546 194.0
HKD1_k127_6469932_18 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000002553 176.0
HKD1_k127_6469932_19 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000000000000000000000002496 180.0
HKD1_k127_6469932_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 585.0
HKD1_k127_6469932_20 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000002566 184.0
HKD1_k127_6469932_21 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000259 182.0
HKD1_k127_6469932_22 Transposase - - - 0.000000000000000000000000000000000000000000001263 176.0
HKD1_k127_6469932_23 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000001209 169.0
HKD1_k127_6469932_24 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000001014 183.0
HKD1_k127_6469932_25 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000002231 168.0
HKD1_k127_6469932_26 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000134 152.0
HKD1_k127_6469932_27 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000105 154.0
HKD1_k127_6469932_28 - - - - 0.000000000000000000000000000000365 132.0
HKD1_k127_6469932_29 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000001346 122.0
HKD1_k127_6469932_3 phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 565.0
HKD1_k127_6469932_30 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000003676 126.0
HKD1_k127_6469932_31 Trypsin-like serine protease - - - 0.000000000000000000000000000728 124.0
HKD1_k127_6469932_32 - - - - 0.000000000000000000000000001501 120.0
HKD1_k127_6469932_33 Protein chain release factor B K15034 - - 0.000000000000000000000000002748 116.0
HKD1_k127_6469932_34 Belongs to the universal stress protein A family - - - 0.00000000000000000000000002992 120.0
HKD1_k127_6469932_35 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000003143 112.0
HKD1_k127_6469932_36 membrane - - - 0.0000000000000000000000112 108.0
HKD1_k127_6469932_37 PFAM Beta-propeller repeat - - - 0.0000000000000000000000411 116.0
HKD1_k127_6469932_38 membrane - - - 0.000000000000000000003041 101.0
HKD1_k127_6469932_39 peptide chain release factor K15034 - - 0.0000000000000000002199 92.0
HKD1_k127_6469932_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 464.0
HKD1_k127_6469932_40 Protein of unknown function (DUF2905) - - - 0.00000000000007417 74.0
HKD1_k127_6469932_41 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000002389 66.0
HKD1_k127_6469932_42 response regulator, receiver - - - 0.0000001733 59.0
HKD1_k127_6469932_43 P-type ATPase K01537 - 3.6.3.8 0.000005866 54.0
HKD1_k127_6469932_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 392.0
HKD1_k127_6469932_6 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 380.0
HKD1_k127_6469932_7 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 375.0
HKD1_k127_6469932_8 Serine dehydrogenase proteinase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD1_k127_6469932_9 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 308.0
HKD1_k127_6470530_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 542.0
HKD1_k127_6470530_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 464.0
HKD1_k127_6470530_10 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 337.0
HKD1_k127_6470530_11 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 325.0
HKD1_k127_6470530_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 325.0
HKD1_k127_6470530_13 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 321.0
HKD1_k127_6470530_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006158 279.0
HKD1_k127_6470530_15 Putative esterase K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009736 267.0
HKD1_k127_6470530_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HKD1_k127_6470530_17 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001266 246.0
HKD1_k127_6470530_18 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006549 254.0
HKD1_k127_6470530_19 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000261 239.0
HKD1_k127_6470530_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 462.0
HKD1_k127_6470530_20 esterase - - - 0.00000000000000000000000000000000000000000000000000000000002217 213.0
HKD1_k127_6470530_21 YCII-related domain - - - 0.0000000000000000000000000000000000007377 145.0
HKD1_k127_6470530_22 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000001084 139.0
HKD1_k127_6470530_23 - - - - 0.0000000000000000000000000000007129 131.0
HKD1_k127_6470530_25 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000000004646 115.0
HKD1_k127_6470530_26 OsmC-like protein K04063 - - 0.0000000000000000000000005105 109.0
HKD1_k127_6470530_27 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.00000000000000000000006801 107.0
HKD1_k127_6470530_28 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000002085 98.0
HKD1_k127_6470530_29 Transglycosylase associated protein - - - 0.00000000000000000002173 92.0
HKD1_k127_6470530_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
HKD1_k127_6470530_30 Acid phosphatase homologues - - - 0.0000000000000000005886 98.0
HKD1_k127_6470530_31 lysyltransferase activity K07027 - - 0.0000000003913 73.0
HKD1_k127_6470530_32 Domain of unknown function (DUF4203) - - - 0.000004589 56.0
HKD1_k127_6470530_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 417.0
HKD1_k127_6470530_5 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 406.0
HKD1_k127_6470530_6 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 386.0
HKD1_k127_6470530_7 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
HKD1_k127_6470530_8 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 371.0
HKD1_k127_6470530_9 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 334.0
HKD1_k127_6473631_0 - - - - 0.0 1657.0
HKD1_k127_6473631_1 peptidyl-serine autophosphorylation - - - 1.024e-282 916.0
HKD1_k127_6473631_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 520.0
HKD1_k127_6473631_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 472.0
HKD1_k127_6473631_12 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 478.0
HKD1_k127_6473631_13 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 451.0
HKD1_k127_6473631_14 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 404.0
HKD1_k127_6473631_15 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 393.0
HKD1_k127_6473631_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 398.0
HKD1_k127_6473631_17 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 386.0
HKD1_k127_6473631_18 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 387.0
HKD1_k127_6473631_19 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 333.0
HKD1_k127_6473631_2 chaperone-mediated protein folding K12132 - 2.7.11.1 1.439e-271 865.0
HKD1_k127_6473631_20 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 340.0
HKD1_k127_6473631_21 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
HKD1_k127_6473631_22 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 335.0
HKD1_k127_6473631_23 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 314.0
HKD1_k127_6473631_24 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 302.0
HKD1_k127_6473631_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 305.0
HKD1_k127_6473631_26 hydrolase family 20, catalytic K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
HKD1_k127_6473631_27 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001432 271.0
HKD1_k127_6473631_28 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
HKD1_k127_6473631_29 serine-type peptidase activity - GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009393 278.0
HKD1_k127_6473631_3 intracellular protein transport - - - 5.271e-260 830.0
HKD1_k127_6473631_30 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
HKD1_k127_6473631_31 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
HKD1_k127_6473631_32 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000003966 207.0
HKD1_k127_6473631_33 - - - - 0.000000000000000000000000000000000000000000000000000000001944 209.0
HKD1_k127_6473631_34 - - - - 0.00000000000000000000000000000000000000000000000000002573 191.0
HKD1_k127_6473631_35 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000003945 200.0
HKD1_k127_6473631_36 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000001166 192.0
HKD1_k127_6473631_37 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000002556 178.0
HKD1_k127_6473631_38 Metal dependent phosphohydrolases with conserved 'HD' motif. K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000005776 167.0
HKD1_k127_6473631_4 Epoxide hydrolase N terminus K01253,K21159 - 3.3.2.9 1.309e-204 651.0
HKD1_k127_6473631_40 - - - - 0.00000000000000000000000000000000000003774 152.0
HKD1_k127_6473631_41 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000005776 161.0
HKD1_k127_6473631_42 Putative lumazine-binding - - - 0.000000000000000000000000000000009083 132.0
HKD1_k127_6473631_43 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000001164 132.0
HKD1_k127_6473631_44 - - - - 0.0000000000000000000000000004128 120.0
HKD1_k127_6473631_45 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001903 107.0
HKD1_k127_6473631_46 MerR, DNA binding K13639 - - 0.0000000000000000000002188 102.0
HKD1_k127_6473631_47 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000003254 96.0
HKD1_k127_6473631_48 - - - - 0.000000000000000000132 101.0
HKD1_k127_6473631_49 ECF sigma factor - - - 0.0000000000000000002026 98.0
HKD1_k127_6473631_5 Epoxide hydrolase N terminus K21159 - - 1.048e-194 616.0
HKD1_k127_6473631_50 Cupin 2, conserved barrel domain protein - - - 0.000000000000000001609 95.0
HKD1_k127_6473631_51 Cold shock protein domain - - - 0.00000000000000001864 87.0
HKD1_k127_6473631_52 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000001036 78.0
HKD1_k127_6473631_53 - - - - 0.0000000000008623 76.0
HKD1_k127_6473631_54 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000006742 72.0
HKD1_k127_6473631_55 - - - - 0.0000000003037 66.0
HKD1_k127_6473631_57 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000004038 52.0
HKD1_k127_6473631_58 cAMP biosynthetic process - - - 0.00005465 50.0
HKD1_k127_6473631_59 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.0003638 46.0
HKD1_k127_6473631_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 617.0
HKD1_k127_6473631_7 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 610.0
HKD1_k127_6473631_8 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 631.0
HKD1_k127_6473631_9 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 591.0
HKD1_k127_6510764_0 conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008353 271.0
HKD1_k127_6510764_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000001809 218.0
HKD1_k127_6510764_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001959 191.0
HKD1_k127_6515823_0 cellulose binding - - - 0.0 1360.0
HKD1_k127_6515823_1 4Fe-4S dicluster domain K00184 - - 0.0 1135.0
HKD1_k127_6515823_10 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 551.0
HKD1_k127_6515823_11 Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 537.0
HKD1_k127_6515823_12 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 523.0
HKD1_k127_6515823_13 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 468.0
HKD1_k127_6515823_14 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 440.0
HKD1_k127_6515823_15 protease-associated PA domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 421.0
HKD1_k127_6515823_16 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 412.0
HKD1_k127_6515823_17 - K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 408.0
HKD1_k127_6515823_18 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 368.0
HKD1_k127_6515823_19 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 354.0
HKD1_k127_6515823_2 Dienelactone hydrolase family - - - 1.217e-242 774.0
HKD1_k127_6515823_20 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 353.0
HKD1_k127_6515823_21 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 364.0
HKD1_k127_6515823_22 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
HKD1_k127_6515823_23 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 350.0
HKD1_k127_6515823_24 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 323.0
HKD1_k127_6515823_25 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
HKD1_k127_6515823_26 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 314.0
HKD1_k127_6515823_27 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000323 286.0
HKD1_k127_6515823_28 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001019 262.0
HKD1_k127_6515823_29 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 262.0
HKD1_k127_6515823_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 1.803e-228 737.0
HKD1_k127_6515823_30 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002682 254.0
HKD1_k127_6515823_31 SMART ATPase, AAA type, core K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000001539 253.0
HKD1_k127_6515823_32 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000009833 248.0
HKD1_k127_6515823_33 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000004641 243.0
HKD1_k127_6515823_34 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000007275 213.0
HKD1_k127_6515823_35 Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000194 211.0
HKD1_k127_6515823_36 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000001344 199.0
HKD1_k127_6515823_37 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
HKD1_k127_6515823_38 PFAM 2Fe-2S -binding K00256,K03518,K07302,K07303,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000009066 190.0
HKD1_k127_6515823_39 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000004596 171.0
HKD1_k127_6515823_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.846e-203 640.0
HKD1_k127_6515823_40 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000007674 161.0
HKD1_k127_6515823_41 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000002571 153.0
HKD1_k127_6515823_42 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000002111 147.0
HKD1_k127_6515823_43 DinB family - - - 0.000000000000000000000000000000000003044 144.0
HKD1_k127_6515823_44 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000001005 151.0
HKD1_k127_6515823_45 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000002762 139.0
HKD1_k127_6515823_46 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000001131 139.0
HKD1_k127_6515823_47 Trehalose utilisation - - - 0.00000000000000000000000000000001815 142.0
HKD1_k127_6515823_48 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000392 126.0
HKD1_k127_6515823_49 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000009803 136.0
HKD1_k127_6515823_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 4.046e-203 659.0
HKD1_k127_6515823_50 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000254 124.0
HKD1_k127_6515823_51 peptidase activity K06889 - - 0.00000000000000000000000000647 123.0
HKD1_k127_6515823_52 receptor K02014 - - 0.00000000000000000000001472 117.0
HKD1_k127_6515823_53 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000002269 95.0
HKD1_k127_6515823_55 - - - - 0.0000000000000000006433 93.0
HKD1_k127_6515823_56 - - - - 0.000000000000000001748 92.0
HKD1_k127_6515823_57 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000005018 78.0
HKD1_k127_6515823_58 WD40-like Beta Propeller Repeat - - - 0.00000000000001095 88.0
HKD1_k127_6515823_59 cell adhesion involved in biofilm formation - - - 0.00000000000005754 86.0
HKD1_k127_6515823_6 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 615.0
HKD1_k127_6515823_60 Secretin N-terminal domain K12282 - - 0.00000000000006563 84.0
HKD1_k127_6515823_61 tetratricopeptide repeat - - - 0.0000000000002561 82.0
HKD1_k127_6515823_62 SnoaL-like polyketide cyclase - - - 0.0000000001006 68.0
HKD1_k127_6515823_63 Transcriptional regulator, arsR - - - 0.0000000004525 63.0
HKD1_k127_6515823_64 PFAM regulatory protein ArsR - - - 0.000000003733 67.0
HKD1_k127_6515823_65 Domain of unknown function (DUF4390) - - - 0.00000003359 62.0
HKD1_k127_6515823_66 Family membership - - - 0.00005983 56.0
HKD1_k127_6515823_67 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0001064 53.0
HKD1_k127_6515823_7 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 610.0
HKD1_k127_6515823_8 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 572.0
HKD1_k127_6515823_9 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 569.0
HKD1_k127_6589098_0 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 409.0
HKD1_k127_6589098_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 408.0
HKD1_k127_6589098_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 373.0
HKD1_k127_6589098_3 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001869 271.0
HKD1_k127_6589098_4 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007622 248.0
HKD1_k127_6589098_5 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000001927 244.0
HKD1_k127_6589098_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
HKD1_k127_6589098_7 - - - - 0.00000000000000000000000000000000000000000003161 172.0
HKD1_k127_6589098_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000001211 82.0
HKD1_k127_6589098_9 - - - - 0.0002192 53.0
HKD1_k127_6590344_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 8.955e-284 886.0
HKD1_k127_6590344_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.7e-209 672.0
HKD1_k127_6590344_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 345.0
HKD1_k127_6590344_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 336.0
HKD1_k127_6590344_12 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 302.0
HKD1_k127_6590344_13 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000006059 254.0
HKD1_k127_6590344_14 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001446 263.0
HKD1_k127_6590344_15 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000007423 248.0
HKD1_k127_6590344_16 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
HKD1_k127_6590344_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000006122 229.0
HKD1_k127_6590344_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000004219 212.0
HKD1_k127_6590344_19 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000002266 204.0
HKD1_k127_6590344_2 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 624.0
HKD1_k127_6590344_20 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000152 173.0
HKD1_k127_6590344_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000002442 160.0
HKD1_k127_6590344_22 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000001238 145.0
HKD1_k127_6590344_23 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000001318 138.0
HKD1_k127_6590344_24 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000001716 110.0
HKD1_k127_6590344_25 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000000001141 99.0
HKD1_k127_6590344_26 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000001005 82.0
HKD1_k127_6590344_27 23S rRNA-intervening sequence protein - - - 0.000002042 53.0
HKD1_k127_6590344_28 Glycolate oxidase subunit K00104 - 1.1.3.15 0.000146 48.0
HKD1_k127_6590344_29 AntiSigma factor - - - 0.000189 51.0
HKD1_k127_6590344_3 peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 600.0
HKD1_k127_6590344_30 PFAM PKD domain containing protein - - - 0.0008255 49.0
HKD1_k127_6590344_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 578.0
HKD1_k127_6590344_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 528.0
HKD1_k127_6590344_6 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 494.0
HKD1_k127_6590344_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
HKD1_k127_6590344_8 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 398.0
HKD1_k127_6590344_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 393.0
HKD1_k127_6642314_0 Glycogen debranching enzyme - - - 1.543e-246 766.0
HKD1_k127_6642314_1 serine dehydratase beta chain K01752 - 4.3.1.17 2.104e-241 758.0
HKD1_k127_6642314_2 Alpha amylase, catalytic domain - - - 1.026e-219 690.0
HKD1_k127_6642314_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 541.0
HKD1_k127_6642314_4 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 526.0
HKD1_k127_6642314_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 473.0
HKD1_k127_6642314_6 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 430.0
HKD1_k127_6642314_7 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001426 285.0
HKD1_k127_6642314_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000001586 156.0
HKD1_k127_679323_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 519.0
HKD1_k127_679323_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 408.0
HKD1_k127_679323_11 - - - - 0.000000000001101 76.0
HKD1_k127_679323_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 409.0
HKD1_k127_679323_3 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000032 238.0
HKD1_k127_679323_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000501 196.0
HKD1_k127_679323_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000004383 205.0
HKD1_k127_679323_6 O-Antigen ligase K18814 - - 0.000000000000000000000000000000000000000000009221 177.0
HKD1_k127_679323_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000003044 133.0
HKD1_k127_679323_8 Cold shock K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000004271 117.0
HKD1_k127_679323_9 Trm112p-like protein K09791 - - 0.0000000000000000003111 88.0
HKD1_k127_6851416_0 Sodium:solute symporter family - - - 1.95e-239 752.0
HKD1_k127_6851416_1 - - - - 0.00000000000003162 83.0
HKD1_k127_6851416_2 Type II secretion system protein G K02456 - - 0.0003855 43.0
HKD1_k127_7004117_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 453.0
HKD1_k127_7004117_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000002456 181.0
HKD1_k127_7004117_2 integral membrane protein - - - 0.000000000000000000000000000000003711 143.0
HKD1_k127_7004117_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000002301 137.0
HKD1_k127_7004117_4 - - - - 0.00000000000000000000000000007071 134.0
HKD1_k127_7004117_5 methyltransferase - - - 0.000000007394 69.0
HKD1_k127_7004117_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00002856 46.0
HKD1_k127_7044938_0 Sodium:solute symporter family K03307 - - 1.31e-226 714.0
HKD1_k127_7044938_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 592.0
HKD1_k127_7044938_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000001281 100.0
HKD1_k127_7044938_12 - - - - 0.00000000005825 64.0
HKD1_k127_7044938_13 Haem-NO-binding - - - 0.0005415 49.0
HKD1_k127_7044938_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 428.0
HKD1_k127_7044938_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
HKD1_k127_7044938_4 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HKD1_k127_7044938_5 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 266.0
HKD1_k127_7044938_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000003731 222.0
HKD1_k127_7044938_7 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000001225 193.0
HKD1_k127_7044938_8 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000001149 180.0
HKD1_k127_7044938_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000199 138.0
HKD1_k127_7047924_0 FAD linked oxidases, C-terminal domain - - - 0.0 1276.0
HKD1_k127_7047924_1 Sortilin, neurotensin receptor 3, - - - 0.0 1208.0
HKD1_k127_7047924_10 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 514.0
HKD1_k127_7047924_11 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 494.0
HKD1_k127_7047924_12 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 434.0
HKD1_k127_7047924_13 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 447.0
HKD1_k127_7047924_14 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 437.0
HKD1_k127_7047924_15 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 437.0
HKD1_k127_7047924_16 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 429.0
HKD1_k127_7047924_17 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 392.0
HKD1_k127_7047924_18 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 388.0
HKD1_k127_7047924_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
HKD1_k127_7047924_2 Thiamine pyrophosphate enzyme, central domain K00156 - 1.2.5.1 4.948e-302 935.0
HKD1_k127_7047924_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 321.0
HKD1_k127_7047924_21 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
HKD1_k127_7047924_22 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002378 272.0
HKD1_k127_7047924_23 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001294 267.0
HKD1_k127_7047924_24 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000009473 209.0
HKD1_k127_7047924_25 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000004175 218.0
HKD1_k127_7047924_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000001724 218.0
HKD1_k127_7047924_27 Periplasmic binding protein-like domain K10439 - - 0.00000000000000000000000000000000000000000000000000002082 203.0
HKD1_k127_7047924_28 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000002823 196.0
HKD1_k127_7047924_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000001723 170.0
HKD1_k127_7047924_3 glycoside hydrolase family 38 K01191 - 3.2.1.24 1.649e-286 916.0
HKD1_k127_7047924_30 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000001028 100.0
HKD1_k127_7047924_31 COG0845 Membrane-fusion protein - - - 0.000000000003901 78.0
HKD1_k127_7047924_32 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000398 72.0
HKD1_k127_7047924_4 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 587.0
HKD1_k127_7047924_5 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 597.0
HKD1_k127_7047924_6 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 552.0
HKD1_k127_7047924_7 Major facilitator Superfamily K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 531.0
HKD1_k127_7047924_8 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 534.0
HKD1_k127_7047924_9 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 521.0
HKD1_k127_7074694_0 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000001042 114.0
HKD1_k127_7074694_1 - - - - 0.000000000000000000000005341 113.0
HKD1_k127_7074694_2 GIY-YIG catalytic domain - - - 0.0000000000000000001944 90.0
HKD1_k127_7086501_0 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 498.0
HKD1_k127_7086501_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 357.0
HKD1_k127_7086501_2 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000000000001568 145.0
HKD1_k127_7086501_3 ROK family - - - 0.00000000000000000000000001251 124.0
HKD1_k127_7086501_4 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000001355 123.0
HKD1_k127_7086501_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000002262 91.0
HKD1_k127_7092376_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1129.0
HKD1_k127_7092376_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1127.0
HKD1_k127_7092376_10 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 573.0
HKD1_k127_7092376_11 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 541.0
HKD1_k127_7092376_12 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 535.0
HKD1_k127_7092376_13 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 551.0
HKD1_k127_7092376_14 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 511.0
HKD1_k127_7092376_15 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 414.0
HKD1_k127_7092376_16 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 384.0
HKD1_k127_7092376_17 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 341.0
HKD1_k127_7092376_18 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 329.0
HKD1_k127_7092376_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 299.0
HKD1_k127_7092376_2 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1111.0
HKD1_k127_7092376_20 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 295.0
HKD1_k127_7092376_21 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003644 285.0
HKD1_k127_7092376_22 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001332 274.0
HKD1_k127_7092376_23 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003144 278.0
HKD1_k127_7092376_24 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000004473 265.0
HKD1_k127_7092376_25 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000003001 236.0
HKD1_k127_7092376_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000005425 219.0
HKD1_k127_7092376_27 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000003925 213.0
HKD1_k127_7092376_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000002599 210.0
HKD1_k127_7092376_29 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000001314 195.0
HKD1_k127_7092376_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 7.954e-321 1009.0
HKD1_k127_7092376_30 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000006926 191.0
HKD1_k127_7092376_31 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000004555 185.0
HKD1_k127_7092376_32 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000007146 179.0
HKD1_k127_7092376_33 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000001518 170.0
HKD1_k127_7092376_34 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000002056 178.0
HKD1_k127_7092376_35 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000084 175.0
HKD1_k127_7092376_36 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000004997 158.0
HKD1_k127_7092376_37 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000101 158.0
HKD1_k127_7092376_38 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000012 139.0
HKD1_k127_7092376_39 oxidoreductase activity - - - 0.0000000000000000000000000000004175 141.0
HKD1_k127_7092376_4 MacB-like periplasmic core domain - - - 4.503e-268 850.0
HKD1_k127_7092376_40 Domain of unknown function (DUF4824) - - - 0.0000000000000000000000000000007405 136.0
HKD1_k127_7092376_41 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000284 100.0
HKD1_k127_7092376_42 - - - - 0.0000000000000000000005013 106.0
HKD1_k127_7092376_43 CAAX protease self-immunity K07052 - - 0.0000000000000000001782 100.0
HKD1_k127_7092376_44 - - - - 0.000000000000000001135 92.0
HKD1_k127_7092376_45 - - - - 0.0000000000000326 74.0
HKD1_k127_7092376_46 PBS lyase HEAT-like repeat - - - 0.000000000000417 81.0
HKD1_k127_7092376_47 - - - - 0.000000000004252 78.0
HKD1_k127_7092376_48 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000002586 71.0
HKD1_k127_7092376_49 outer membrane autotransporter barrel domain protein - - - 0.0000001939 61.0
HKD1_k127_7092376_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 1.148e-243 760.0
HKD1_k127_7092376_6 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.844e-233 733.0
HKD1_k127_7092376_7 Sodium:solute symporter family K03307 - - 4.061e-233 733.0
HKD1_k127_7092376_8 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 2.32e-222 695.0
HKD1_k127_7092376_9 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 8.113e-211 670.0
HKD1_k127_7100903_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1356.0
HKD1_k127_7100903_1 ASPIC and UnbV - - - 3.593e-238 749.0
HKD1_k127_7100903_10 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 362.0
HKD1_k127_7100903_11 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 332.0
HKD1_k127_7100903_12 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 287.0
HKD1_k127_7100903_13 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000267 267.0
HKD1_k127_7100903_14 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001812 245.0
HKD1_k127_7100903_15 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000517 245.0
HKD1_k127_7100903_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005399 244.0
HKD1_k127_7100903_17 - - - - 0.00000000000000000000000000000000000000000000006601 184.0
HKD1_k127_7100903_18 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000001197 136.0
HKD1_k127_7100903_19 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000002652 124.0
HKD1_k127_7100903_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 632.0
HKD1_k127_7100903_20 - - - - 0.00000000000000000000001559 118.0
HKD1_k127_7100903_21 cheY-homologous receiver domain - - - 0.0000000000000000002137 94.0
HKD1_k127_7100903_22 Belongs to the UPF0102 family K07460 - - 0.000000000000000001448 92.0
HKD1_k127_7100903_23 PFAM PEGA domain - - - 0.000000000000001201 92.0
HKD1_k127_7100903_24 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.00000000000001955 81.0
HKD1_k127_7100903_25 Protein tyrosine kinase - - - 0.0000000000001001 85.0
HKD1_k127_7100903_26 Domain of unknown function (DUF1844) - - - 0.0000000000003315 72.0
HKD1_k127_7100903_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 544.0
HKD1_k127_7100903_4 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 482.0
HKD1_k127_7100903_5 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 501.0
HKD1_k127_7100903_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
HKD1_k127_7100903_7 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 461.0
HKD1_k127_7100903_8 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 432.0
HKD1_k127_7100903_9 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 422.0
HKD1_k127_7106720_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1230.0
HKD1_k127_7106720_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 5.049e-199 645.0
HKD1_k127_7106720_10 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 318.0
HKD1_k127_7106720_11 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 331.0
HKD1_k127_7106720_12 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000038 285.0
HKD1_k127_7106720_13 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003317 304.0
HKD1_k127_7106720_14 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000001207 220.0
HKD1_k127_7106720_15 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000000001529 185.0
HKD1_k127_7106720_16 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000002027 183.0
HKD1_k127_7106720_17 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000000000000000000000001815 159.0
HKD1_k127_7106720_18 BMC domain - - - 0.0000000000000000000000000000001432 127.0
HKD1_k127_7106720_19 Pkd domain containing protein - - - 0.000000000000000000002723 112.0
HKD1_k127_7106720_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 570.0
HKD1_k127_7106720_20 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000003261 92.0
HKD1_k127_7106720_21 peptidase A24A prepilin type IV K02278 - 3.4.23.43 0.0000000000002637 78.0
HKD1_k127_7106720_22 TadE-like protein - - - 0.00000001414 63.0
HKD1_k127_7106720_23 acetyltransferase involved in intracellular survival and related acetyltransferases - - - 0.0000004604 62.0
HKD1_k127_7106720_24 pathogenesis - - - 0.000003713 62.0
HKD1_k127_7106720_25 Protein of unknown function (DUF1634) - - - 0.000004154 53.0
HKD1_k127_7106720_26 Flp Fap pilin component - - - 0.00006997 49.0
HKD1_k127_7106720_27 Flp Fap pilin component - - - 0.0001298 51.0
HKD1_k127_7106720_28 His Kinase A (phosphoacceptor) domain - - - 0.0002911 52.0
HKD1_k127_7106720_3 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 544.0
HKD1_k127_7106720_4 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 462.0
HKD1_k127_7106720_5 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 441.0
HKD1_k127_7106720_6 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 428.0
HKD1_k127_7106720_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 419.0
HKD1_k127_7106720_8 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 389.0
HKD1_k127_7106720_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 344.0
HKD1_k127_7117985_0 PFAM Integrase catalytic K07497 - - 0.0000000000000000000000000000003234 126.0
HKD1_k127_7117985_1 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000006754 121.0
HKD1_k127_7117985_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000002127 72.0
HKD1_k127_7117985_3 - - - - 0.0002915 50.0
HKD1_k127_7126505_0 cellulose binding - - - 0.0 1119.0
HKD1_k127_7126505_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 1.28e-275 862.0
HKD1_k127_7126505_2 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 6.854e-259 810.0
HKD1_k127_7126505_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 531.0
HKD1_k127_7126505_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 519.0
HKD1_k127_7126505_5 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000000007944 102.0
HKD1_k127_7126505_6 amine dehydrogenase activity - - - 0.000001236 61.0
HKD1_k127_7138680_0 metallocarboxypeptidase activity K14054 - - 0.0 1144.0
HKD1_k127_7138680_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 6.112e-256 799.0
HKD1_k127_7138680_10 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 483.0
HKD1_k127_7138680_11 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 411.0
HKD1_k127_7138680_12 Crystallin, zeta (quinone reductase) K00344 GO:0000166,GO:0003008,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003960,GO:0005198,GO:0005212,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006805,GO:0007600,GO:0007601,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032501,GO:0036094,GO:0042178,GO:0042221,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050877,GO:0050896,GO:0050953,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070402,GO:0070887,GO:0071466,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 334.0
HKD1_k127_7138680_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 331.0
HKD1_k127_7138680_14 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 318.0
HKD1_k127_7138680_15 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
HKD1_k127_7138680_16 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 282.0
HKD1_k127_7138680_17 Ectoine utilization protein EutC K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001771 265.0
HKD1_k127_7138680_18 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002363 257.0
HKD1_k127_7138680_19 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
HKD1_k127_7138680_2 helicase activity - - - 1.329e-254 813.0
HKD1_k127_7138680_20 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000002296 237.0
HKD1_k127_7138680_21 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
HKD1_k127_7138680_22 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000003597 228.0
HKD1_k127_7138680_23 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
HKD1_k127_7138680_24 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000001064 211.0
HKD1_k127_7138680_25 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000486 216.0
HKD1_k127_7138680_26 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000008067 194.0
HKD1_k127_7138680_27 Anabaena sensory rhodopsin transducer - - - 0.0000000000000000000000000000000000000000000000001538 181.0
HKD1_k127_7138680_28 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000009068 184.0
HKD1_k127_7138680_29 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000001198 170.0
HKD1_k127_7138680_3 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 6.699e-211 662.0
HKD1_k127_7138680_30 WYL domain K13572 - - 0.000000000000000000000000000000000000000000702 171.0
HKD1_k127_7138680_31 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000007328 158.0
HKD1_k127_7138680_32 Phospholipid methyltransferase - - - 0.00000000000000000000000000000001118 136.0
HKD1_k127_7138680_33 cheY-homologous receiver domain - - - 0.000000000000000000000000761 112.0
HKD1_k127_7138680_34 Belongs to the peptidase S8 family - - - 0.00000000000000000000006508 115.0
HKD1_k127_7138680_35 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000003558 105.0
HKD1_k127_7138680_36 RNA recognition motif - - - 0.00000000000000001398 90.0
HKD1_k127_7138680_37 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000579 92.0
HKD1_k127_7138680_38 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.000000000000001459 87.0
HKD1_k127_7138680_39 - - - - 0.00000000000000387 85.0
HKD1_k127_7138680_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.766e-198 624.0
HKD1_k127_7138680_40 - - - - 0.00000000002599 66.0
HKD1_k127_7138680_41 sensory perception of sound - - - 0.00000752 52.0
HKD1_k127_7138680_42 UPF0391 membrane protein - - - 0.0001312 47.0
HKD1_k127_7138680_5 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 575.0
HKD1_k127_7138680_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 567.0
HKD1_k127_7138680_7 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 524.0
HKD1_k127_7138680_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 482.0
HKD1_k127_7138680_9 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 476.0
HKD1_k127_7169273_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 1.128e-225 708.0
HKD1_k127_7169273_1 mandelate racemase muconate lactonizing K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000006502 252.0
HKD1_k127_7170468_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.114e-261 816.0
HKD1_k127_7170468_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.29e-210 689.0
HKD1_k127_7170468_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000005921 200.0
HKD1_k127_7170468_11 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000001415 186.0
HKD1_k127_7170468_12 PFAM FRG domain - - - 0.000000000000000000000000000136 117.0
HKD1_k127_7170468_13 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000001436 115.0
HKD1_k127_7170468_14 Helix-turn-helix domain K15539 - - 0.0000000000000000004033 97.0
HKD1_k127_7170468_15 AAA ATPase domain - - - 0.0000000009889 70.0
HKD1_k127_7170468_16 - - - - 0.000000006051 59.0
HKD1_k127_7170468_17 Glycosyltransferase family 87 K13671 - - 0.000002348 59.0
HKD1_k127_7170468_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 590.0
HKD1_k127_7170468_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 532.0
HKD1_k127_7170468_4 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 474.0
HKD1_k127_7170468_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 458.0
HKD1_k127_7170468_6 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 455.0
HKD1_k127_7170468_7 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001379 286.0
HKD1_k127_7170468_8 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
HKD1_k127_7170468_9 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000001137 233.0
HKD1_k127_7172588_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 6.827e-265 839.0
HKD1_k127_7172588_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 2.462e-238 766.0
HKD1_k127_7172588_10 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 352.0
HKD1_k127_7172588_11 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
HKD1_k127_7172588_12 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 318.0
HKD1_k127_7172588_13 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 317.0
HKD1_k127_7172588_14 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 314.0
HKD1_k127_7172588_15 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 297.0
HKD1_k127_7172588_16 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008482 297.0
HKD1_k127_7172588_17 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001834 282.0
HKD1_k127_7172588_18 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000004316 252.0
HKD1_k127_7172588_19 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005978 257.0
HKD1_k127_7172588_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 591.0
HKD1_k127_7172588_20 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000007999 253.0
HKD1_k127_7172588_21 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000376 244.0
HKD1_k127_7172588_22 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000001094 233.0
HKD1_k127_7172588_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000008518 229.0
HKD1_k127_7172588_24 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000001656 219.0
HKD1_k127_7172588_25 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.0000000000000000000000000000000000000000000000000000000001061 216.0
HKD1_k127_7172588_26 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000006589 190.0
HKD1_k127_7172588_27 Transposase - - - 0.00000000000000000000000000000000000000000000002172 183.0
HKD1_k127_7172588_28 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000006448 154.0
HKD1_k127_7172588_29 6,7-dimethyl-8-ribityllumazine synthase K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000001213 147.0
HKD1_k127_7172588_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 559.0
HKD1_k127_7172588_30 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000000000000000000000000959 137.0
HKD1_k127_7172588_31 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000008521 113.0
HKD1_k127_7172588_32 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000002098 94.0
HKD1_k127_7172588_33 - - - - 0.00000000000000004499 86.0
HKD1_k127_7172588_34 unfolded protein binding K06142 - - 0.0000000000001563 79.0
HKD1_k127_7172588_35 TonB C terminal - - - 0.000000005152 68.0
HKD1_k127_7172588_36 Predicted membrane protein (DUF2085) - - - 0.00000001742 63.0
HKD1_k127_7172588_37 bacterial OsmY and nodulation domain K04065 - - 0.00001029 55.0
HKD1_k127_7172588_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 501.0
HKD1_k127_7172588_5 acyl-CoA dehydrogenase activity K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 458.0
HKD1_k127_7172588_6 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 416.0
HKD1_k127_7172588_7 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 399.0
HKD1_k127_7172588_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 396.0
HKD1_k127_7172588_9 Surface antigen variable number K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 393.0
HKD1_k127_7238585_0 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 596.0
HKD1_k127_7238585_1 - - - - 0.000000000000000000000000000000000000000000000000000000000008555 218.0
HKD1_k127_7238585_2 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
HKD1_k127_7238585_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000001266 166.0
HKD1_k127_7238585_4 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000001274 130.0
HKD1_k127_7238585_5 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000004534 124.0
HKD1_k127_7247266_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 4.647e-197 627.0
HKD1_k127_7247266_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 467.0
HKD1_k127_7247266_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 451.0
HKD1_k127_7247266_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 293.0
HKD1_k127_7247266_4 Evidence 5 No homology to any previously reported sequences K09005 - - 0.000000000000000000000000001355 126.0
HKD1_k127_7247266_5 Glycosyl transferase family 41 - - - 0.00000000000003953 83.0
HKD1_k127_7247266_6 Belongs to the ompA family K03286 - - 0.0001147 45.0
HKD1_k127_7265883_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1186.0
HKD1_k127_7265883_1 ABC transporter, transmembrane K18890 - - 4.985e-208 662.0
HKD1_k127_7265883_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
HKD1_k127_7265883_11 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 372.0
HKD1_k127_7265883_12 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 343.0
HKD1_k127_7265883_13 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 322.0
HKD1_k127_7265883_14 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 320.0
HKD1_k127_7265883_15 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 311.0
HKD1_k127_7265883_16 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 306.0
HKD1_k127_7265883_17 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 292.0
HKD1_k127_7265883_18 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005787 303.0
HKD1_k127_7265883_19 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 283.0
HKD1_k127_7265883_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.815e-203 653.0
HKD1_k127_7265883_20 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003673 286.0
HKD1_k127_7265883_21 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 260.0
HKD1_k127_7265883_22 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002866 280.0
HKD1_k127_7265883_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
HKD1_k127_7265883_24 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 260.0
HKD1_k127_7265883_25 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000002734 249.0
HKD1_k127_7265883_26 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004812 236.0
HKD1_k127_7265883_27 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
HKD1_k127_7265883_28 Male sterility protein K15891 - 1.1.1.354 0.00000000000000000000000000000000000000000000000000000000001634 218.0
HKD1_k127_7265883_29 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000002235 208.0
HKD1_k127_7265883_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.936e-197 645.0
HKD1_k127_7265883_30 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000003018 218.0
HKD1_k127_7265883_31 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000004181 212.0
HKD1_k127_7265883_32 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000001168 212.0
HKD1_k127_7265883_33 PFAM Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000008012 188.0
HKD1_k127_7265883_34 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000002339 196.0
HKD1_k127_7265883_35 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000001209 187.0
HKD1_k127_7265883_36 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000002335 190.0
HKD1_k127_7265883_37 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000004348 175.0
HKD1_k127_7265883_38 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000002253 152.0
HKD1_k127_7265883_39 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000002884 151.0
HKD1_k127_7265883_4 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 578.0
HKD1_k127_7265883_41 S1 P1 Nuclease - - - 0.0000000000000000000000000000000000501 147.0
HKD1_k127_7265883_42 peptidase - - - 0.000000000000000000000000000000001777 145.0
HKD1_k127_7265883_43 MgtC family K07507 - - 0.000000000000000000000000000000002706 133.0
HKD1_k127_7265883_44 DinB family - - - 0.00000000000000000000000003535 113.0
HKD1_k127_7265883_45 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000002561 95.0
HKD1_k127_7265883_46 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002955 85.0
HKD1_k127_7265883_47 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.000000000000000005592 89.0
HKD1_k127_7265883_48 PFAM von Willebrand factor type A K07114 - - 0.00000000000000002505 93.0
HKD1_k127_7265883_49 3D domain - - - 0.000000000000002167 85.0
HKD1_k127_7265883_5 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 543.0
HKD1_k127_7265883_50 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000006734 82.0
HKD1_k127_7265883_51 Belongs to the eIF-2B alpha beta delta subunits family - - - 0.00000000000001781 86.0
HKD1_k127_7265883_52 Hsp20/alpha crystallin family K13993 - - 0.0000000000003813 75.0
HKD1_k127_7265883_53 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000003247 70.0
HKD1_k127_7265883_54 - - - - 0.00000000002084 72.0
HKD1_k127_7265883_55 Matrixin - - - 0.0000000001765 74.0
HKD1_k127_7265883_56 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000003026 61.0
HKD1_k127_7265883_58 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000005215 58.0
HKD1_k127_7265883_59 nuclear chromosome segregation - - - 0.0000000853 64.0
HKD1_k127_7265883_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 528.0
HKD1_k127_7265883_60 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00001887 55.0
HKD1_k127_7265883_61 - - - - 0.0001275 48.0
HKD1_k127_7265883_7 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 515.0
HKD1_k127_7265883_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 451.0
HKD1_k127_7265883_9 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 463.0
HKD1_k127_7273704_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000667 209.0
HKD1_k127_7273704_1 PFAM ATP-binding region - - - 0.000000000000000000002624 96.0
HKD1_k127_7273704_2 Response regulator receiver - - - 0.00000000004026 70.0
HKD1_k127_7273704_3 Archease protein family (MTH1598/TM1083) - - - 0.00001866 48.0
HKD1_k127_7376645_0 permease K03303 - - 7.919e-209 655.0
HKD1_k127_7376645_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 339.0
HKD1_k127_7468256_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 552.0
HKD1_k127_7468256_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 497.0
HKD1_k127_7468256_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 412.0
HKD1_k127_7468256_11 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 342.0
HKD1_k127_7468256_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 342.0
HKD1_k127_7468256_13 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 326.0
HKD1_k127_7468256_14 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 329.0
HKD1_k127_7468256_15 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 332.0
HKD1_k127_7468256_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 316.0
HKD1_k127_7468256_17 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 306.0
HKD1_k127_7468256_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005892 284.0
HKD1_k127_7468256_19 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009712 270.0
HKD1_k127_7468256_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 487.0
HKD1_k127_7468256_20 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000134 260.0
HKD1_k127_7468256_21 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000008879 249.0
HKD1_k127_7468256_22 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000001387 184.0
HKD1_k127_7468256_23 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000155 183.0
HKD1_k127_7468256_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000001161 164.0
HKD1_k127_7468256_25 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000000003468 147.0
HKD1_k127_7468256_26 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000006097 143.0
HKD1_k127_7468256_27 Yqey-like protein K09117 - - 0.000000000000000000000000000000000005956 141.0
HKD1_k127_7468256_28 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000006754 141.0
HKD1_k127_7468256_29 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000002112 135.0
HKD1_k127_7468256_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 453.0
HKD1_k127_7468256_30 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000001377 128.0
HKD1_k127_7468256_31 PAP2 superfamily - - - 0.00000000000000000000000008507 117.0
HKD1_k127_7468256_32 Acetyltransferase (GNAT) domain - - - 0.00000000000000001383 94.0
HKD1_k127_7468256_33 Evidence 5 No homology to any previously reported sequences - - - 0.000000001638 65.0
HKD1_k127_7468256_34 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000004815 67.0
HKD1_k127_7468256_35 Type II secretory pathway, component HofQ K02666 - - 0.00006495 53.0
HKD1_k127_7468256_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 451.0
HKD1_k127_7468256_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 439.0
HKD1_k127_7468256_6 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 455.0
HKD1_k127_7468256_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 422.0
HKD1_k127_7468256_8 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 421.0
HKD1_k127_7468256_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 409.0
HKD1_k127_7474805_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1556.0
HKD1_k127_7474805_1 AcrB/AcrD/AcrF family - - - 0.0 1194.0
HKD1_k127_7474805_10 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 571.0
HKD1_k127_7474805_100 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
HKD1_k127_7474805_101 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000008061 154.0
HKD1_k127_7474805_102 acid phosphatase activity - - - 0.000000000000000000000000000000000004874 155.0
HKD1_k127_7474805_103 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000007244 150.0
HKD1_k127_7474805_104 - - - - 0.00000000000000000000000000000000001096 141.0
HKD1_k127_7474805_105 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000002386 139.0
HKD1_k127_7474805_106 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000007224 143.0
HKD1_k127_7474805_107 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000006697 134.0
HKD1_k127_7474805_108 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000002191 141.0
HKD1_k127_7474805_109 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000004028 127.0
HKD1_k127_7474805_11 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 575.0
HKD1_k127_7474805_110 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000004301 136.0
HKD1_k127_7474805_111 Biogenesis protein - - - 0.0000000000000000000000000000001775 134.0
HKD1_k127_7474805_112 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000009558 130.0
HKD1_k127_7474805_113 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000001287 127.0
HKD1_k127_7474805_114 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001309 132.0
HKD1_k127_7474805_115 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000003093 122.0
HKD1_k127_7474805_116 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000249 126.0
HKD1_k127_7474805_117 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000008023 118.0
HKD1_k127_7474805_118 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000001709 113.0
HKD1_k127_7474805_119 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000009036 115.0
HKD1_k127_7474805_12 DNA polymerase X K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 551.0
HKD1_k127_7474805_120 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000001742 121.0
HKD1_k127_7474805_121 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000002556 110.0
HKD1_k127_7474805_122 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000002166 103.0
HKD1_k127_7474805_123 - - - - 0.00000000000000000000006038 109.0
HKD1_k127_7474805_124 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000001801 107.0
HKD1_k127_7474805_125 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K10810 - 2.5.1.3,5.3.99.10 0.000000000000000000001307 106.0
HKD1_k127_7474805_126 Sulfurtransferase - - - 0.000000000000000002026 87.0
HKD1_k127_7474805_127 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000001388 87.0
HKD1_k127_7474805_129 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000008606 91.0
HKD1_k127_7474805_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 540.0
HKD1_k127_7474805_130 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000166 89.0
HKD1_k127_7474805_131 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.0000000000000003909 88.0
HKD1_k127_7474805_132 Regulatory protein, FmdB family - - - 0.0000000000000007663 79.0
HKD1_k127_7474805_133 Helix-turn-helix domain K15539 - - 0.000000000000007565 85.0
HKD1_k127_7474805_134 KH domain - - - 0.000000000000008559 79.0
HKD1_k127_7474805_135 Rhs element Vgr protein - - - 0.00000000000001948 77.0
HKD1_k127_7474805_136 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000005093 86.0
HKD1_k127_7474805_137 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001612 73.0
HKD1_k127_7474805_138 radical SAM domain protein - - - 0.0000000000001721 83.0
HKD1_k127_7474805_139 Bacterial regulatory protein, Fis family - - - 0.0000000000001772 72.0
HKD1_k127_7474805_14 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 545.0
HKD1_k127_7474805_140 SNARE associated Golgi protein - - - 0.0000000000004649 74.0
HKD1_k127_7474805_141 Fimbrial assembly protein (PilN) K02663 - - 0.000000000001868 80.0
HKD1_k127_7474805_142 Tetratricopeptide repeats - - - 0.00000000000393 74.0
HKD1_k127_7474805_143 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000007128 73.0
HKD1_k127_7474805_144 - - - - 0.00000000002599 66.0
HKD1_k127_7474805_145 universal stress protein - - - 0.0000000001419 72.0
HKD1_k127_7474805_146 Heat induced stress protein YflT - - - 0.000000002825 65.0
HKD1_k127_7474805_147 - - - - 0.000000004868 71.0
HKD1_k127_7474805_148 Heavy-metal resistance - - - 0.0000006412 57.0
HKD1_k127_7474805_149 - - - - 0.0000009654 61.0
HKD1_k127_7474805_15 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 529.0
HKD1_k127_7474805_150 FeoA K04758 - - 0.000001692 56.0
HKD1_k127_7474805_151 Pilus assembly protein, PilP K02665 - - 0.00001281 55.0
HKD1_k127_7474805_152 - - - - 0.00003142 55.0
HKD1_k127_7474805_153 RDD family - - - 0.00006746 55.0
HKD1_k127_7474805_154 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0002514 54.0
HKD1_k127_7474805_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 515.0
HKD1_k127_7474805_17 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 503.0
HKD1_k127_7474805_18 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 509.0
HKD1_k127_7474805_19 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 497.0
HKD1_k127_7474805_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.927e-287 915.0
HKD1_k127_7474805_20 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 480.0
HKD1_k127_7474805_21 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 456.0
HKD1_k127_7474805_22 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 443.0
HKD1_k127_7474805_23 HYR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 468.0
HKD1_k127_7474805_24 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
HKD1_k127_7474805_25 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 442.0
HKD1_k127_7474805_26 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 433.0
HKD1_k127_7474805_27 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
HKD1_k127_7474805_28 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 434.0
HKD1_k127_7474805_29 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 436.0
HKD1_k127_7474805_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.635e-284 891.0
HKD1_k127_7474805_30 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 419.0
HKD1_k127_7474805_31 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 418.0
HKD1_k127_7474805_32 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 417.0
HKD1_k127_7474805_33 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 406.0
HKD1_k127_7474805_34 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 391.0
HKD1_k127_7474805_35 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 389.0
HKD1_k127_7474805_36 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 376.0
HKD1_k127_7474805_37 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 353.0
HKD1_k127_7474805_38 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 376.0
HKD1_k127_7474805_39 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 354.0
HKD1_k127_7474805_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 6.928e-255 796.0
HKD1_k127_7474805_40 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 355.0
HKD1_k127_7474805_41 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 360.0
HKD1_k127_7474805_42 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 346.0
HKD1_k127_7474805_43 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 342.0
HKD1_k127_7474805_44 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 335.0
HKD1_k127_7474805_45 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 326.0
HKD1_k127_7474805_46 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 333.0
HKD1_k127_7474805_47 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
HKD1_k127_7474805_48 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 319.0
HKD1_k127_7474805_49 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 332.0
HKD1_k127_7474805_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.26e-228 721.0
HKD1_k127_7474805_50 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 318.0
HKD1_k127_7474805_51 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 316.0
HKD1_k127_7474805_52 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 307.0
HKD1_k127_7474805_53 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 306.0
HKD1_k127_7474805_54 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 305.0
HKD1_k127_7474805_55 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 301.0
HKD1_k127_7474805_56 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 299.0
HKD1_k127_7474805_57 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 295.0
HKD1_k127_7474805_58 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 297.0
HKD1_k127_7474805_59 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 298.0
HKD1_k127_7474805_6 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 4.802e-227 715.0
HKD1_k127_7474805_60 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 286.0
HKD1_k127_7474805_61 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 303.0
HKD1_k127_7474805_62 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001136 297.0
HKD1_k127_7474805_63 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
HKD1_k127_7474805_64 peptidoglycan-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000867 271.0
HKD1_k127_7474805_65 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000009646 277.0
HKD1_k127_7474805_66 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000407 281.0
HKD1_k127_7474805_67 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004803 264.0
HKD1_k127_7474805_68 allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
HKD1_k127_7474805_69 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 270.0
HKD1_k127_7474805_7 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.13e-217 689.0
HKD1_k127_7474805_70 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 262.0
HKD1_k127_7474805_71 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000006256 260.0
HKD1_k127_7474805_72 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009161 256.0
HKD1_k127_7474805_73 Xaa-Pro dipeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000006356 243.0
HKD1_k127_7474805_74 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000002687 218.0
HKD1_k127_7474805_75 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000001643 214.0
HKD1_k127_7474805_76 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000003569 224.0
HKD1_k127_7474805_77 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000001439 203.0
HKD1_k127_7474805_78 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001929 208.0
HKD1_k127_7474805_79 Pfam:AHS1 - - - 0.00000000000000000000000000000000000000000000000000000004802 203.0
HKD1_k127_7474805_8 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.074e-203 658.0
HKD1_k127_7474805_80 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000007172 211.0
HKD1_k127_7474805_81 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000002714 204.0
HKD1_k127_7474805_82 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000004556 203.0
HKD1_k127_7474805_83 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000000000603 196.0
HKD1_k127_7474805_84 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000007244 191.0
HKD1_k127_7474805_85 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000001692 189.0
HKD1_k127_7474805_86 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000005576 188.0
HKD1_k127_7474805_87 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000007167 181.0
HKD1_k127_7474805_88 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000004205 185.0
HKD1_k127_7474805_89 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000008973 178.0
HKD1_k127_7474805_9 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 602.0
HKD1_k127_7474805_90 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000001366 193.0
HKD1_k127_7474805_91 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000005097 181.0
HKD1_k127_7474805_92 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000005443 169.0
HKD1_k127_7474805_93 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000001355 165.0
HKD1_k127_7474805_95 oxidase subunit K08738 - - 0.0000000000000000000000000000000000000009186 167.0
HKD1_k127_7474805_96 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000001139 156.0
HKD1_k127_7474805_97 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000002346 151.0
HKD1_k127_7474805_98 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000282 147.0
HKD1_k127_7474805_99 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000001497 143.0
HKD1_k127_7479640_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 452.0
HKD1_k127_7479640_1 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 347.0
HKD1_k127_7479640_2 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00001983 49.0
HKD1_k127_7480484_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 354.0
HKD1_k127_7480484_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 304.0
HKD1_k127_7480484_2 Tetratricopeptide repeat - - - 0.0000000000000000000001871 106.0
HKD1_k127_7480484_3 Cytochrome c554 and c-prime - - - 0.00000000000000002174 88.0
HKD1_k127_7484591_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 2.922e-291 906.0
HKD1_k127_7484591_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.409e-288 924.0
HKD1_k127_7484591_10 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 352.0
HKD1_k127_7484591_11 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 306.0
HKD1_k127_7484591_12 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 306.0
HKD1_k127_7484591_13 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 298.0
HKD1_k127_7484591_14 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 284.0
HKD1_k127_7484591_15 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001973 274.0
HKD1_k127_7484591_16 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003739 276.0
HKD1_k127_7484591_17 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000572 291.0
HKD1_k127_7484591_18 Cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001954 257.0
HKD1_k127_7484591_19 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009378 265.0
HKD1_k127_7484591_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 1.035e-212 682.0
HKD1_k127_7484591_20 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001072 244.0
HKD1_k127_7484591_21 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
HKD1_k127_7484591_22 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000003824 218.0
HKD1_k127_7484591_23 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000007102 208.0
HKD1_k127_7484591_24 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000008592 204.0
HKD1_k127_7484591_25 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000005829 190.0
HKD1_k127_7484591_26 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000001057 197.0
HKD1_k127_7484591_27 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000003992 186.0
HKD1_k127_7484591_28 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000005285 175.0
HKD1_k127_7484591_29 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000001122 177.0
HKD1_k127_7484591_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 501.0
HKD1_k127_7484591_30 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000134 177.0
HKD1_k127_7484591_31 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000002029 152.0
HKD1_k127_7484591_32 Transcription termination factor nusG - - - 0.000000000000000000000000000000001238 136.0
HKD1_k127_7484591_33 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000002297 143.0
HKD1_k127_7484591_34 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000006016 143.0
HKD1_k127_7484591_35 Belongs to the ompA family - - - 0.00000000000000000000000000000003111 134.0
HKD1_k127_7484591_36 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000001624 134.0
HKD1_k127_7484591_37 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000008767 123.0
HKD1_k127_7484591_38 DoxX K15977 - - 0.00000000000000000000000001678 114.0
HKD1_k127_7484591_39 PFAM PEGA domain - - - 0.00000000000000000000000004681 126.0
HKD1_k127_7484591_4 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 494.0
HKD1_k127_7484591_40 Protein of unknown function (DUF1326) - - - 0.00000000000000000002115 99.0
HKD1_k127_7484591_41 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000001598 76.0
HKD1_k127_7484591_42 PFAM Amino acid-binding ACT - - - 0.00000000002061 69.0
HKD1_k127_7484591_43 - - - - 0.0000000005228 66.0
HKD1_k127_7484591_44 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000001926 59.0
HKD1_k127_7484591_45 Protein of unknown function (DUF1059) - - - 0.000002418 58.0
HKD1_k127_7484591_46 Endonuclease Exonuclease Phosphatase - - - 0.000003527 58.0
HKD1_k127_7484591_47 Stress responsive A/B Barrel Domain - - - 0.000148 51.0
HKD1_k127_7484591_48 - - - - 0.0009521 49.0
HKD1_k127_7484591_5 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 468.0
HKD1_k127_7484591_6 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 441.0
HKD1_k127_7484591_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 421.0
HKD1_k127_7484591_8 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 379.0
HKD1_k127_7484591_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 390.0
HKD1_k127_7498883_0 Dienelactone hydrolase family - - - 9.613e-244 772.0
HKD1_k127_7498883_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 7.963e-227 736.0
HKD1_k127_7498883_2 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 4.988e-202 654.0
HKD1_k127_7498883_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 464.0
HKD1_k127_7498883_4 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 356.0
HKD1_k127_7498883_5 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000003728 152.0
HKD1_k127_7498883_6 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000000003612 165.0
HKD1_k127_7498883_7 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000001065 149.0
HKD1_k127_7498883_8 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000007121 112.0
HKD1_k127_7547521_0 Glycogen debranching enzyme - - - 3.743e-236 754.0
HKD1_k127_7547521_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 467.0
HKD1_k127_7547521_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00008191 48.0
HKD1_k127_7605152_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 381.0
HKD1_k127_7605152_1 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000000000003517 159.0
HKD1_k127_7629603_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 524.0
HKD1_k127_7629603_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 404.0
HKD1_k127_7629603_2 NmrA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 335.0
HKD1_k127_7629603_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
HKD1_k127_7629603_4 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001402 237.0
HKD1_k127_7629603_5 membrane - - - 0.000000000000008515 75.0
HKD1_k127_7629603_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000149 66.0
HKD1_k127_7629603_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000007661 55.0
HKD1_k127_7780754_0 Cytochrome c - - - 0.0 1138.0
HKD1_k127_7780754_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 4.897e-268 838.0
HKD1_k127_7780754_10 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 408.0
HKD1_k127_7780754_11 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 404.0
HKD1_k127_7780754_12 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 373.0
HKD1_k127_7780754_13 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 319.0
HKD1_k127_7780754_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HKD1_k127_7780754_15 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007635 264.0
HKD1_k127_7780754_16 - - - - 0.0000000000000000000000000000000000000000000000000000002873 216.0
HKD1_k127_7780754_17 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000001952 211.0
HKD1_k127_7780754_18 - - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD1_k127_7780754_19 - - - - 0.00000000000000000000000000000000000000000000000000205 194.0
HKD1_k127_7780754_2 competence protein COMEC - - - 1.962e-232 757.0
HKD1_k127_7780754_20 DinB superfamily - - - 0.000000000000000000000000000000000000000000000002941 179.0
HKD1_k127_7780754_21 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000004019 189.0
HKD1_k127_7780754_22 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000209 177.0
HKD1_k127_7780754_23 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000001114 177.0
HKD1_k127_7780754_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000004216 138.0
HKD1_k127_7780754_25 Peptidoglycan-binding domain 1 protein K01207,K01447,K03806,K11066 - 3.2.1.52,3.5.1.28 0.000000000000000000000000000000315 139.0
HKD1_k127_7780754_26 MacB-like periplasmic core domain - - - 0.00000000000000000000000000009198 131.0
HKD1_k127_7780754_27 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000009379 125.0
HKD1_k127_7780754_29 - - - - 0.0000000000000000000008577 109.0
HKD1_k127_7780754_3 Fungalysin metallopeptidase (M36) - - - 2.207e-221 722.0
HKD1_k127_7780754_30 cytochrome C peroxidase - - - 0.0000000000000000001145 95.0
HKD1_k127_7780754_31 - - - - 0.00000000000114 74.0
HKD1_k127_7780754_32 - - - - 0.000000000006211 77.0
HKD1_k127_7780754_33 MacB-like periplasmic core domain - - - 0.0000000003053 61.0
HKD1_k127_7780754_34 Pregnancy-associated plasma protein-A - - - 0.0005888 46.0
HKD1_k127_7780754_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 595.0
HKD1_k127_7780754_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 577.0
HKD1_k127_7780754_6 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 585.0
HKD1_k127_7780754_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 540.0
HKD1_k127_7780754_8 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 464.0
HKD1_k127_7780754_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 443.0
HKD1_k127_7823849_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 456.0
HKD1_k127_7823849_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 442.0
HKD1_k127_7823849_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 397.0
HKD1_k127_7823849_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006122 282.0
HKD1_k127_7823849_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000003536 232.0
HKD1_k127_7823849_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
HKD1_k127_7823849_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001775 205.0
HKD1_k127_7823849_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000005953 161.0
HKD1_k127_7823849_8 chaperone-mediated protein folding - - - 0.0000000000000002513 93.0
HKD1_k127_7823849_9 Preprotein translocase, YajC subunit K03210 - - 0.00000000000005549 77.0
HKD1_k127_7824297_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000004963 166.0
HKD1_k127_7824297_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000004391 145.0
HKD1_k127_7824297_2 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.000000000000000000000000000009913 122.0
HKD1_k127_7833715_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 455.0
HKD1_k127_7833715_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 375.0
HKD1_k127_7833715_2 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 357.0
HKD1_k127_7833715_3 gtp cyclohydrolase K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 261.0
HKD1_k127_7833715_4 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000009073 205.0
HKD1_k127_7833715_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000001114 150.0
HKD1_k127_7847416_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 7.212e-298 920.0
HKD1_k127_7847416_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 7.527e-294 923.0
HKD1_k127_7847416_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 425.0
HKD1_k127_7847416_11 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 398.0
HKD1_k127_7847416_12 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 325.0
HKD1_k127_7847416_13 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 296.0
HKD1_k127_7847416_14 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006431 290.0
HKD1_k127_7847416_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002558 291.0
HKD1_k127_7847416_16 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
HKD1_k127_7847416_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 253.0
HKD1_k127_7847416_18 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000007402 250.0
HKD1_k127_7847416_19 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000299 236.0
HKD1_k127_7847416_2 Cyclic nucleotide-monophosphate binding domain - - - 2.173e-197 625.0
HKD1_k127_7847416_20 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
HKD1_k127_7847416_21 transcriptional regulator K22106 - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
HKD1_k127_7847416_22 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001994 224.0
HKD1_k127_7847416_23 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000004447 213.0
HKD1_k127_7847416_24 - - - - 0.00000000000000000000000000000000000000000000000000002163 195.0
HKD1_k127_7847416_26 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000009144 173.0
HKD1_k127_7847416_28 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000002632 152.0
HKD1_k127_7847416_29 Doxx family - - - 0.00000000000000000000000000000000000003135 148.0
HKD1_k127_7847416_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 637.0
HKD1_k127_7847416_30 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000004904 145.0
HKD1_k127_7847416_31 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000002859 141.0
HKD1_k127_7847416_32 secondary active sulfate transmembrane transporter activity - - - 0.000000000000000000000000000002905 128.0
HKD1_k127_7847416_33 AntiSigma factor - - - 0.0000000000000000000000007485 116.0
HKD1_k127_7847416_34 Pfam:DUF2029 - - - 0.00000000000000000000004199 112.0
HKD1_k127_7847416_35 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000001988 110.0
HKD1_k127_7847416_36 methyltransferase - - - 0.00000000000000007468 89.0
HKD1_k127_7847416_37 - - - - 0.0000000000000001193 83.0
HKD1_k127_7847416_38 PGAP1-like protein - - - 0.000000011 66.0
HKD1_k127_7847416_39 Protein of unknown function (DUF1059) - - - 0.00000004452 56.0
HKD1_k127_7847416_4 acyl-CoA dehydrogenase activity K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 588.0
HKD1_k127_7847416_40 Putative zinc-finger - - - 0.0000001281 62.0
HKD1_k127_7847416_41 PFAM Integrase core domain K07497 - - 0.0005311 42.0
HKD1_k127_7847416_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 592.0
HKD1_k127_7847416_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 489.0
HKD1_k127_7847416_7 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 475.0
HKD1_k127_7847416_8 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 467.0
HKD1_k127_7847416_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 428.0
HKD1_k127_7863811_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1274.0
HKD1_k127_7863811_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.387e-287 906.0
HKD1_k127_7863811_10 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 8.394e-202 650.0
HKD1_k127_7863811_11 ATP-dependent DNA helicase K03657 - 3.6.4.12 3.957e-195 633.0
HKD1_k127_7863811_12 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
HKD1_k127_7863811_13 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 508.0
HKD1_k127_7863811_14 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 492.0
HKD1_k127_7863811_15 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 500.0
HKD1_k127_7863811_16 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 487.0
HKD1_k127_7863811_17 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
HKD1_k127_7863811_18 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 468.0
HKD1_k127_7863811_19 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 462.0
HKD1_k127_7863811_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.045e-273 862.0
HKD1_k127_7863811_20 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
HKD1_k127_7863811_21 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
HKD1_k127_7863811_22 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 376.0
HKD1_k127_7863811_23 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 384.0
HKD1_k127_7863811_24 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 364.0
HKD1_k127_7863811_25 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 358.0
HKD1_k127_7863811_26 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 360.0
HKD1_k127_7863811_27 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 340.0
HKD1_k127_7863811_28 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 324.0
HKD1_k127_7863811_29 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HKD1_k127_7863811_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.646e-262 822.0
HKD1_k127_7863811_30 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
HKD1_k127_7863811_31 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 299.0
HKD1_k127_7863811_32 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001233 295.0
HKD1_k127_7863811_33 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004646 291.0
HKD1_k127_7863811_34 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001876 280.0
HKD1_k127_7863811_35 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
HKD1_k127_7863811_36 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 281.0
HKD1_k127_7863811_37 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 269.0
HKD1_k127_7863811_38 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003715 265.0
HKD1_k127_7863811_39 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001338 263.0
HKD1_k127_7863811_4 amino acid - - - 1.526e-250 790.0
HKD1_k127_7863811_40 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000001479 260.0
HKD1_k127_7863811_41 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
HKD1_k127_7863811_42 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001936 216.0
HKD1_k127_7863811_43 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000001121 196.0
HKD1_k127_7863811_44 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000005595 190.0
HKD1_k127_7863811_45 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000006392 174.0
HKD1_k127_7863811_46 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000009155 142.0
HKD1_k127_7863811_47 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000001974 134.0
HKD1_k127_7863811_48 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000002676 131.0
HKD1_k127_7863811_49 - - - - 0.0000000000000000000000000000008928 131.0
HKD1_k127_7863811_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.117e-232 728.0
HKD1_k127_7863811_50 Regulatory protein, FmdB - - - 0.0000000000000000000000008777 106.0
HKD1_k127_7863811_51 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000003867 110.0
HKD1_k127_7863811_52 - - - - 0.000000000000000000000004915 114.0
HKD1_k127_7863811_53 - - - - 0.0000000000000000000001107 104.0
HKD1_k127_7863811_54 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000111 100.0
HKD1_k127_7863811_55 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000004909 100.0
HKD1_k127_7863811_56 Tetratricopeptide repeat - - - 0.00000000000000004947 89.0
HKD1_k127_7863811_57 Domain of unknown function (DUF4136) - - - 0.0000000000000003522 86.0
HKD1_k127_7863811_58 R3H domain protein K06346 - - 0.000000000000001101 82.0
HKD1_k127_7863811_59 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000001473 85.0
HKD1_k127_7863811_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.104e-230 722.0
HKD1_k127_7863811_60 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002064 73.0
HKD1_k127_7863811_61 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000007849 75.0
HKD1_k127_7863811_62 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000002456 66.0
HKD1_k127_7863811_63 - - - - 0.000000009902 64.0
HKD1_k127_7863811_64 long-chain fatty acid transport protein - - - 0.000006509 58.0
HKD1_k127_7863811_65 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000009469 56.0
HKD1_k127_7863811_66 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00001758 52.0
HKD1_k127_7863811_7 alpha-galactosidase - - - 1.625e-228 727.0
HKD1_k127_7863811_8 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 2.788e-224 717.0
HKD1_k127_7863811_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.632e-217 684.0
HKD1_k127_7942703_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.338e-291 915.0
HKD1_k127_7942703_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
HKD1_k127_7959750_0 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 508.0
HKD1_k127_7959750_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
HKD1_k127_7959750_2 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000000001641 181.0
HKD1_k127_7959750_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000001033 98.0
HKD1_k127_7959750_4 TIGRFAM pentapeptide MXKDX repeat protein - - - 0.00002766 52.0
HKD1_k127_7979844_0 Patatin-like phospholipase - - - 3.662e-206 674.0
HKD1_k127_7979844_1 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 495.0
HKD1_k127_7979844_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 289.0
HKD1_k127_7979844_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006816 242.0
HKD1_k127_7979844_4 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000001754 135.0
HKD1_k127_7979844_5 - - - - 0.000000000000002559 85.0
HKD1_k127_7979844_6 alpha beta - - - 0.00000000000003412 85.0
HKD1_k127_7979844_7 RDD family - - - 0.0000001949 65.0
HKD1_k127_7979844_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000302 52.0
HKD1_k127_7979844_9 membrane protein domain - - - 0.00003636 58.0
HKD1_k127_7988500_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 285.0
HKD1_k127_7988500_1 - - - - 0.0000000000000000000000000000000000000000000000002368 185.0
HKD1_k127_7988500_2 Amidohydrolase family - - - 0.000000000000000000000000000000001516 139.0
HKD1_k127_7988500_3 - - - - 0.00000000000000000000000000000001752 131.0
HKD1_k127_7993728_0 Heat shock 70 kDa protein K04043 - - 1.027e-304 945.0
HKD1_k127_7993728_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 308.0
HKD1_k127_7993728_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 294.0
HKD1_k127_7993728_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000004321 228.0
HKD1_k127_7993728_4 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000002521 205.0
HKD1_k127_7993728_5 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000001224 155.0
HKD1_k127_7993728_6 - - - - 0.0000000000000000000000000000000000389 141.0
HKD1_k127_8034102_0 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 383.0
HKD1_k127_8034102_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000006356 204.0
HKD1_k127_8034102_2 cyclohydrolase - - - 0.00000000000000000000000009952 114.0
HKD1_k127_82130_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 544.0
HKD1_k127_82130_1 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 350.0
HKD1_k127_82130_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 321.0
HKD1_k127_82130_3 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000001421 199.0
HKD1_k127_82130_4 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000000001156 178.0
HKD1_k127_83117_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 556.0
HKD1_k127_83117_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 379.0
HKD1_k127_83117_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 361.0
HKD1_k127_83117_3 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005129 280.0
HKD1_k127_83117_4 response regulator K02481,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001855 265.0
HKD1_k127_83117_5 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000001536 143.0
HKD1_k127_83117_6 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000005443 135.0
HKD1_k127_83117_7 von Willebrand factor, type A - - - 0.000000000000000000000000006384 128.0
HKD1_k127_83117_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0001234 54.0
HKD1_k127_942849_0 ATPase of the PP-loop superfamily implicated in cell cycle control - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 567.0
HKD1_k127_942849_1 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 475.0
HKD1_k127_942849_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 363.0
HKD1_k127_942849_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
HKD1_k127_942849_4 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007665 256.0
HKD1_k127_942849_5 ATPase of the PP-loop superfamily implicated in cell cycle control - - - 0.0000000004006 61.0
HKD1_k127_99724_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 593.0
HKD1_k127_99724_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 476.0
HKD1_k127_99724_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 408.0
HKD1_k127_99724_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 340.0
HKD1_k127_99724_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 331.0
HKD1_k127_99724_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 319.0
HKD1_k127_99724_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000000006202 198.0
HKD1_k127_99724_7 protein conserved in bacteria K03749 - - 0.0001681 52.0
HKD1_k127_99724_8 Tetratricopeptide repeat - - - 0.0005671 49.0