Overview

ID MAG01742
Name HKD1_bin.6
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus OLB17
Species
Assembly information
Completeness (%) 63.65
Contamination (%) 1.14
GC content (%) 52.0
N50 (bp) 6,395
Genome size (bp) 2,630,394

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2305

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1013173_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.988e-227 717.0
HKD1_k127_1013173_1 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000001616 237.0
HKD1_k127_1013173_2 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000001011 104.0
HKD1_k127_1013173_3 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.000000000000000000001831 109.0
HKD1_k127_1013173_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000005201 95.0
HKD1_k127_1014632_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 342.0
HKD1_k127_1014632_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001697 276.0
HKD1_k127_1014632_2 - - - - 0.00000000000000000000000000000000000000004588 172.0
HKD1_k127_1014632_3 - - - - 0.0000000000000000000000000003629 121.0
HKD1_k127_1014632_4 Glycosyl Transferase K19002 - 2.4.1.337 0.00000000000000000000001261 115.0
HKD1_k127_1022584_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 477.0
HKD1_k127_1022584_1 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001876 280.0
HKD1_k127_1022584_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006627 267.0
HKD1_k127_1022584_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009358 258.0
HKD1_k127_1022584_4 Beta/gamma crystallins - - - 0.00000000000000000000000000001218 131.0
HKD1_k127_1022584_5 oxidoreductase activity K07114 - - 0.000000001256 71.0
HKD1_k127_1022584_6 - - - - 0.0000003248 52.0
HKD1_k127_1022584_7 - - - - 0.0000926 49.0
HKD1_k127_1023392_0 Belongs to the aldehyde dehydrogenase family K00128,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 5.922e-227 711.0
HKD1_k127_1023392_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 423.0
HKD1_k127_1027334_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 569.0
HKD1_k127_1027334_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
HKD1_k127_1056839_0 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HKD1_k127_1056839_1 - - - - 0.000000000000000000000000000000000008808 142.0
HKD1_k127_105756_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.573e-211 667.0
HKD1_k127_105756_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000005909 100.0
HKD1_k127_1067898_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21344 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000296 261.0
HKD1_k127_1067898_1 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001423 235.0
HKD1_k127_1067898_2 Methyltransferase domain - - - 0.0000000000000000000000000459 116.0
HKD1_k127_1067898_3 PFAM Polysaccharide biosynthesis protein - - - 0.0000000001686 70.0
HKD1_k127_1069316_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 542.0
HKD1_k127_1069316_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 410.0
HKD1_k127_1069316_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000004375 229.0
HKD1_k127_1069316_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000001031 159.0
HKD1_k127_1069316_4 Rossmann-like domain - - - 0.000000000000000000000000000002116 131.0
HKD1_k127_1069316_5 - - - - 0.0007961 44.0
HKD1_k127_107182_0 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 558.0
HKD1_k127_107182_1 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 269.0
HKD1_k127_107182_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
HKD1_k127_107182_3 Nickel-containing superoxide dismutase K00518 - 1.15.1.1 0.00000000000000000000000000000000000000000007738 163.0
HKD1_k127_107182_4 - K07018 - - 0.0000000000000000000000000000000000000003122 156.0
HKD1_k127_107182_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000007638 133.0
HKD1_k127_107182_6 Acyl-CoA hydrolase K10806 - - 0.0000000000000000000000000009785 116.0
HKD1_k127_107182_7 - - - - 0.0000000000000000001871 89.0
HKD1_k127_1074282_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000006128 256.0
HKD1_k127_1074282_1 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.0000000000000000000000000000000002083 136.0
HKD1_k127_1084424_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 399.0
HKD1_k127_1084424_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
HKD1_k127_1084424_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000002347 195.0
HKD1_k127_1084424_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000003402 194.0
HKD1_k127_1084424_4 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000001333 155.0
HKD1_k127_1084424_5 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000006386 148.0
HKD1_k127_1086479_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 454.0
HKD1_k127_1086479_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 369.0
HKD1_k127_1086479_2 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002477 236.0
HKD1_k127_1086479_3 HNH endonuclease - - - 0.00000000000000000000000000000000003916 140.0
HKD1_k127_1086479_4 - - - - 0.00000000000000000000000000009705 123.0
HKD1_k127_1086479_5 - - - - 0.00000000000000001934 87.0
HKD1_k127_1087809_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000007934 188.0
HKD1_k127_1087809_1 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000000000005867 146.0
HKD1_k127_1087809_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000003577 147.0
HKD1_k127_1087809_3 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 0.0000000000000002054 81.0
HKD1_k127_1099258_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 344.0
HKD1_k127_1099258_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 337.0
HKD1_k127_1099258_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 333.0
HKD1_k127_1099258_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 308.0
HKD1_k127_1099258_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 293.0
HKD1_k127_1099258_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
HKD1_k127_1099258_6 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000001506 216.0
HKD1_k127_1099258_7 - - - - 0.00000000000000000000000000000000000000000000000000000088 199.0
HKD1_k127_1099258_8 Yip1 domain - - - 0.00000000000786 75.0
HKD1_k127_1111678_0 glutamate--cysteine ligase - - - 1.686e-203 652.0
HKD1_k127_1111678_1 Succinylglutamate desuccinylase / Aspartoacylase family K05526 - 3.5.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000296 273.0
HKD1_k127_1111678_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000001934 189.0
HKD1_k127_1111678_3 - - - - 0.0000000000000000000000000000000000000000000002889 176.0
HKD1_k127_1113154_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 484.0
HKD1_k127_1113154_1 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000002819 210.0
HKD1_k127_1113154_2 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000001212 183.0
HKD1_k127_1113154_3 -acetyltransferase - - - 0.00000000000000000000001005 107.0
HKD1_k127_1113154_4 - - - - 0.000000000000003653 84.0
HKD1_k127_1113520_0 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000001438 207.0
HKD1_k127_1113520_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000003586 185.0
HKD1_k127_1113520_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000009209 179.0
HKD1_k127_1113520_3 - - - - 0.0000000000000000002196 91.0
HKD1_k127_1130777_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.946e-320 989.0
HKD1_k127_1130777_1 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 349.0
HKD1_k127_1130777_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 265.0
HKD1_k127_1130777_3 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000001115 217.0
HKD1_k127_1130777_4 Uncharacterized protein family UPF0016 - - - 0.000000000000000000255 90.0
HKD1_k127_1130777_5 Adenylate cyclase K01768 - 4.6.1.1 0.0001691 51.0
HKD1_k127_113804_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 497.0
HKD1_k127_113804_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000856 168.0
HKD1_k127_113804_2 Glycogen debranching enzyme N terminal - - - 0.000000000000000000005552 94.0
HKD1_k127_1143895_0 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
HKD1_k127_1143895_1 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000001033 164.0
HKD1_k127_1143895_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000006973 130.0
HKD1_k127_1143895_3 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000014 95.0
HKD1_k127_1155485_0 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.0000000000000000000000001575 116.0
HKD1_k127_1155485_1 LppP/LprE lipoprotein - - - 0.00000000004425 67.0
HKD1_k127_1155485_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000002978 64.0
HKD1_k127_1167356_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 518.0
HKD1_k127_1167356_1 Polysaccharide lyase family 4, domain III - - - 0.00000000000000000000000000000000000000000000000000009339 213.0
HKD1_k127_1168441_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 359.0
HKD1_k127_1168441_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000246 166.0
HKD1_k127_1168441_2 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000834 161.0
HKD1_k127_1168441_3 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000004918 65.0
HKD1_k127_1168772_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 361.0
HKD1_k127_1168772_1 PFAM Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 356.0
HKD1_k127_1168772_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000006238 179.0
HKD1_k127_1172654_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
HKD1_k127_1172654_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001747 293.0
HKD1_k127_1177089_0 Lytic transglycosylase catalytic K08307 - - 0.00000000185 70.0
HKD1_k127_1177089_1 (FHA) domain - - - 0.000000005668 68.0
HKD1_k127_1180980_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 562.0
HKD1_k127_1180980_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 480.0
HKD1_k127_1180980_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 328.0
HKD1_k127_1180980_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009414 286.0
HKD1_k127_1180980_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000004244 226.0
HKD1_k127_1180980_5 Zinc carboxypeptidase - - - 0.0000000000000000000000001707 111.0
HKD1_k127_1180980_6 serine threonine protein kinase - - - 0.00007506 54.0
HKD1_k127_1230881_0 protein secretion by the type I secretion system K11085 - - 3.432e-215 679.0
HKD1_k127_1230881_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0002075 48.0
HKD1_k127_1240692_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 291.0
HKD1_k127_1240692_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002968 301.0
HKD1_k127_1249431_0 Peptidase S46 - - - 5.182e-197 634.0
HKD1_k127_1249431_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 387.0
HKD1_k127_1249431_2 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000004214 220.0
HKD1_k127_1249431_3 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000002878 94.0
HKD1_k127_1250187_0 elongation factor G domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 526.0
HKD1_k127_1250187_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000006771 73.0
HKD1_k127_1254326_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 487.0
HKD1_k127_1254326_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 361.0
HKD1_k127_1254326_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000005395 254.0
HKD1_k127_1254326_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000006116 115.0
HKD1_k127_1254326_5 Protein of unknown function (DUF3618) - - - 0.000000000000000003729 96.0
HKD1_k127_1254326_7 Transcriptional regulator antitoxin, MazE K07172 - - 0.0000000009938 63.0
HKD1_k127_1256488_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 614.0
HKD1_k127_1256488_1 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 461.0
HKD1_k127_1256488_2 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 332.0
HKD1_k127_1256488_3 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002286 262.0
HKD1_k127_1256488_4 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000003074 180.0
HKD1_k127_1256488_5 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 0.0000000000000000000000000000000000000000000002976 172.0
HKD1_k127_1256488_6 LUD domain K00782 - - 0.000000000000000000002984 102.0
HKD1_k127_1257841_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 476.0
HKD1_k127_1257841_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 345.0
HKD1_k127_1257841_2 PFAM Acetyltransferase (GNAT) family K06976 - - 0.0000000000000001428 90.0
HKD1_k127_1257841_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000007132 79.0
HKD1_k127_1258146_0 Carboxyl transferase domain - - - 3.141e-209 659.0
HKD1_k127_1258146_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 360.0
HKD1_k127_1258146_2 EVE domain - - - 0.000000000000000000000000000000000000000000005656 166.0
HKD1_k127_127745_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000008367 283.0
HKD1_k127_127745_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000005563 147.0
HKD1_k127_127745_2 Belongs to the Nudix hydrolase family - - - 0.000000000000008687 81.0
HKD1_k127_127745_3 - - - - 0.00000000000001399 79.0
HKD1_k127_127745_4 metalloendopeptidase activity K06834,K08609,K08610 GO:0000003,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009566,GO:0009987,GO:0009988,GO:0016020,GO:0016787,GO:0019538,GO:0019953,GO:0022414,GO:0035036,GO:0043170,GO:0044238,GO:0044464,GO:0044703,GO:0051704,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000003187 77.0
HKD1_k127_1283861_0 Male sterility protein K01897 - 6.2.1.3 2.403e-318 1011.0
HKD1_k127_1283861_1 Glycosyl hydrolase family 47 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 331.0
HKD1_k127_1289308_0 PFAM peptidase T2 asparaginase 2 K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000001893 254.0
HKD1_k127_1289308_1 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000000000000002631 190.0
HKD1_k127_1289308_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000001135 167.0
HKD1_k127_1289308_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000003549 161.0
HKD1_k127_1289308_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000001033 71.0
HKD1_k127_12987_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 473.0
HKD1_k127_12987_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 325.0
HKD1_k127_12987_2 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.000000000000000000000000000000000000000003811 161.0
HKD1_k127_12987_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000002066 135.0
HKD1_k127_12987_4 von Willebrand factor, type A - - - 0.0000000000000000000000000002051 126.0
HKD1_k127_1309405_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HKD1_k127_1309405_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 315.0
HKD1_k127_1317453_0 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000001254 91.0
HKD1_k127_1317453_1 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.000000000000006549 82.0
HKD1_k127_1328227_0 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000019 222.0
HKD1_k127_1328227_1 Parallel beta-helix repeats K12287 - - 0.00000000000000000000000000000000000000000000000000000000003428 232.0
HKD1_k127_1328227_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000002037 162.0
HKD1_k127_1328227_3 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000000001649 144.0
HKD1_k127_1328227_4 Domain of unknown function (DUF5050) - - - 0.000000000000000000000008226 115.0
HKD1_k127_1328227_5 Tetratricopeptide repeat - - - 0.00000000000000000000009977 108.0
HKD1_k127_1328227_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000009891 102.0
HKD1_k127_1328227_7 Cell wall-associated hydrolase (invasion-associated protein) K21471 - - 0.0000000000002101 79.0
HKD1_k127_1343876_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000002781 149.0
HKD1_k127_1343876_1 Bacitracin ABC transporter permease K19302 - 3.6.1.27 0.000000000000000000292 94.0
HKD1_k127_134795_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 558.0
HKD1_k127_134795_1 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 503.0
HKD1_k127_134795_10 metallocarboxypeptidase activity K07752 GO:0006937,GO:0008150,GO:0044057,GO:0050789,GO:0051239,GO:0065007,GO:0090257 3.4.17.22 0.0003046 53.0
HKD1_k127_134795_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 428.0
HKD1_k127_134795_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001343 290.0
HKD1_k127_134795_4 Biopterin-dependent aromatic amino acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000002584 216.0
HKD1_k127_134795_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000002904 184.0
HKD1_k127_134795_6 Protein of unknown function (DUF4199) - - - 0.0000000000000000000000000000000000000000001795 164.0
HKD1_k127_134795_7 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000008231 152.0
HKD1_k127_134795_8 PFAM Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000009333 132.0
HKD1_k127_134795_9 Protein conserved in bacteria - - - 0.000000000000000000001855 95.0
HKD1_k127_1356247_0 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 1.23e-317 987.0
HKD1_k127_1356247_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 8.783e-278 874.0
HKD1_k127_1356247_2 Involved in the tonB-independent uptake of proteins K01730 - 4.2.2.6 1.229e-231 723.0
HKD1_k127_1356247_3 Sialate O-acetylesterase K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 588.0
HKD1_k127_1356247_4 isomerase K01820 - 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 310.0
HKD1_k127_1356247_5 Domain of unknown function (DUF1961) - - - 0.00000000000000000000000002855 115.0
HKD1_k127_1374326_0 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 395.0
HKD1_k127_1374326_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000002059 206.0
HKD1_k127_1374326_2 - - - - 0.00000000000000000000000000000000000000000000000004352 198.0
HKD1_k127_1374326_3 Multicopper oxidase - - - 0.00000000000000000000000000000000006458 150.0
HKD1_k127_1374326_4 N-acetyltransferase K00675 - 2.3.1.118 0.0000000000000000000000026 113.0
HKD1_k127_1376612_0 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 413.0
HKD1_k127_1376612_1 Phage integrase, N-terminal SAM-like domain K14059 - - 0.000000000000000000000000000000000000001019 159.0
HKD1_k127_1376612_2 PFAM TPR repeat-containing protein - - - 0.0003142 52.0
HKD1_k127_1387719_0 transferase activity, transferring acyl groups K14658,K17840,K18815 - 2.3.1.59,2.3.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 499.0
HKD1_k127_1387719_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 424.0
HKD1_k127_1387719_2 Competence protein J (ComJ) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000004971 55.0
HKD1_k127_1392076_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.97e-246 775.0
HKD1_k127_1392076_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 483.0
HKD1_k127_1392076_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001161 242.0
HKD1_k127_1392076_11 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000002462 200.0
HKD1_k127_1392076_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000001471 164.0
HKD1_k127_1392076_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000154 168.0
HKD1_k127_1392076_14 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000003937 164.0
HKD1_k127_1392076_15 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000004551 153.0
HKD1_k127_1392076_16 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000003624 133.0
HKD1_k127_1392076_17 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000006229 126.0
HKD1_k127_1392076_18 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000002161 102.0
HKD1_k127_1392076_19 Lipopolysaccharide-assembly - - - 0.0000000000000000003608 94.0
HKD1_k127_1392076_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 436.0
HKD1_k127_1392076_20 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000008237 80.0
HKD1_k127_1392076_21 zinc-ribbon domain - - - 0.00000000002688 73.0
HKD1_k127_1392076_22 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.000000007333 65.0
HKD1_k127_1392076_3 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 407.0
HKD1_k127_1392076_4 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 402.0
HKD1_k127_1392076_5 PFAM Na-Ca exchanger integrin-beta4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 415.0
HKD1_k127_1392076_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 368.0
HKD1_k127_1392076_7 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 302.0
HKD1_k127_1392076_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
HKD1_k127_1392076_9 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002181 244.0
HKD1_k127_139383_0 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 421.0
HKD1_k127_139383_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 336.0
HKD1_k127_139383_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
HKD1_k127_139383_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000001382 184.0
HKD1_k127_139383_4 Glyoxalase - - - 0.0000000000000000000000000000000000000000000002722 169.0
HKD1_k127_139383_5 Tetratricopeptide repeat - - - 0.00000000000000000000000001727 119.0
HKD1_k127_139383_6 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000006623 106.0
HKD1_k127_139383_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000001639 78.0
HKD1_k127_1400939_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 456.0
HKD1_k127_1400939_1 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 314.0
HKD1_k127_1400939_2 Protein of unknown function (DUF1203) - - - 0.000000000000000000000001224 107.0
HKD1_k127_1400939_3 MerR HTH family regulatory protein - - - 0.000000000583 69.0
HKD1_k127_1409863_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
HKD1_k127_1409863_1 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 366.0
HKD1_k127_1409863_2 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 272.0
HKD1_k127_1409863_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009519 264.0
HKD1_k127_1409863_4 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000000003371 145.0
HKD1_k127_1409863_5 von Willebrand factor, type A K07114,K12511 - - 0.00000000000000000000000000000000003532 146.0
HKD1_k127_1409863_6 ABC transporter, (ATP-binding protein) K06861 - - 0.000000000000000000000000000000001299 130.0
HKD1_k127_1409863_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000001753 121.0
HKD1_k127_1409863_8 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.00000000000000000000009953 102.0
HKD1_k127_1409863_9 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000001956 87.0
HKD1_k127_1445336_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.45e-210 668.0
HKD1_k127_1445336_1 Glycosyl Hydrolase Family 88 - - - 2.78e-202 639.0
HKD1_k127_1445336_2 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 535.0
HKD1_k127_1445336_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
HKD1_k127_1445336_4 Involved in the anomeric conversion of L-rhamnose K03534 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.32 0.0000000000000000000000000000000000000001497 152.0
HKD1_k127_1445336_5 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000002448 132.0
HKD1_k127_146872_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 383.0
HKD1_k127_146872_1 PFAM Binding-protein-dependent transport system inner membrane component K02033,K15581,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 325.0
HKD1_k127_146872_2 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.00000002837 57.0
HKD1_k127_146872_3 ABC transporter substrate-binding protein K15580 - - 0.0000004963 58.0
HKD1_k127_1480370_0 spore germination - - - 0.00000000000000000000000000000000417 135.0
HKD1_k127_1480370_1 Tyrosine phosphatase family - - - 0.0000000000000000000002279 106.0
HKD1_k127_1480370_2 Domain of unknown function (DUF4956) - - - 0.0000000002453 71.0
HKD1_k127_1500290_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 420.0
HKD1_k127_1500290_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 395.0
HKD1_k127_1500290_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000004326 235.0
HKD1_k127_1500290_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000002326 226.0
HKD1_k127_1506811_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 312.0
HKD1_k127_1506811_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 308.0
HKD1_k127_1506811_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000006222 154.0
HKD1_k127_1521802_0 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
HKD1_k127_1521802_1 MafB19-like deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000006692 212.0
HKD1_k127_1521802_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000002314 194.0
HKD1_k127_1521802_3 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.0000000000000000000000000000000000000000009596 160.0
HKD1_k127_1521802_4 Thioredoxin - - - 0.00000000000000000000000000000000000004091 159.0
HKD1_k127_1521802_5 Zinc-binding dehydrogenase - - - 0.0000005909 54.0
HKD1_k127_1521802_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0005507 48.0
HKD1_k127_154182_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 514.0
HKD1_k127_154182_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000008754 195.0
HKD1_k127_154182_2 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000002295 157.0
HKD1_k127_154182_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001797 128.0
HKD1_k127_154182_4 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000002524 93.0
HKD1_k127_1542210_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
HKD1_k127_1542210_1 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000002647 212.0
HKD1_k127_1542210_2 TraB family K09973 - - 0.00000000000000000000000000000000000000007289 157.0
HKD1_k127_1542210_3 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000004209 150.0
HKD1_k127_1545598_0 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 351.0
HKD1_k127_1545598_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 297.0
HKD1_k127_1545598_2 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 297.0
HKD1_k127_1545598_3 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 277.0
HKD1_k127_1545598_4 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000238 243.0
HKD1_k127_1545598_5 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000001125 86.0
HKD1_k127_1556417_0 asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 352.0
HKD1_k127_1556417_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
HKD1_k127_1556417_2 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000054 133.0
HKD1_k127_1556417_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000001199 127.0
HKD1_k127_158765_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.671e-209 665.0
HKD1_k127_158765_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 348.0
HKD1_k127_158765_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
HKD1_k127_158765_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000007137 139.0
HKD1_k127_158765_4 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000001398 86.0
HKD1_k127_158765_5 metal-dependent membrane protease K07052 - - 0.0000000000009013 79.0
HKD1_k127_158765_6 iron ion homeostasis - - - 0.00000000002845 76.0
HKD1_k127_1606761_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 311.0
HKD1_k127_1606761_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 268.0
HKD1_k127_1606761_2 dehydrogenase, E1 component K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004134 265.0
HKD1_k127_1606761_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000007729 99.0
HKD1_k127_1606761_4 Chaperone of endosialidase - - - 0.00000003124 67.0
HKD1_k127_161926_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 350.0
HKD1_k127_161926_1 PAAR motif - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
HKD1_k127_161926_2 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000000000000000000002534 169.0
HKD1_k127_161926_3 Domain of unknown function (DUF4123) - - - 0.0000000000000000000000000000000005653 137.0
HKD1_k127_161926_4 - - - - 0.000000000000000000000001088 111.0
HKD1_k127_161926_5 Domain of unknown function (DUF4123) - - - 0.0000004367 57.0
HKD1_k127_163321_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.514e-246 768.0
HKD1_k127_163321_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 437.0
HKD1_k127_163321_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 390.0
HKD1_k127_163321_3 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 323.0
HKD1_k127_163321_4 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000002072 177.0
HKD1_k127_163321_5 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000000005066 132.0
HKD1_k127_163321_6 3D domain protein - - - 0.0000000000000001358 87.0
HKD1_k127_163321_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000003283 79.0
HKD1_k127_1667743_0 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 4.422e-307 964.0
HKD1_k127_1667743_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.991e-304 960.0
HKD1_k127_1667743_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000001373 207.0
HKD1_k127_1667743_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000005653 137.0
HKD1_k127_1667743_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001146 118.0
HKD1_k127_1667743_5 - - - - 0.0000000000000001937 85.0
HKD1_k127_1674618_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000009117 209.0
HKD1_k127_1674618_1 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000004093 126.0
HKD1_k127_1674618_2 Domain of unknown function (DUF4126) - - - 0.000000000000000001068 89.0
HKD1_k127_16787_0 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
HKD1_k127_16787_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
HKD1_k127_16787_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001799 224.0
HKD1_k127_16787_3 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000005049 181.0
HKD1_k127_16787_4 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000002729 181.0
HKD1_k127_16787_5 nuclease - - - 0.000000000000000000007292 102.0
HKD1_k127_1750906_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007605 250.0
HKD1_k127_1750906_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000004074 100.0
HKD1_k127_1750906_2 - - - - 0.0000007894 59.0
HKD1_k127_176505_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 466.0
HKD1_k127_176505_1 - - - - 0.000000000000000000000000000000000009334 145.0
HKD1_k127_176505_2 NfeD-like C-terminal, partner-binding - - - 0.000000000000001394 83.0
HKD1_k127_1770848_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
HKD1_k127_1770848_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000002812 184.0
HKD1_k127_1770848_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000008324 184.0
HKD1_k127_1770848_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000002844 154.0
HKD1_k127_1770848_4 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000001431 130.0
HKD1_k127_1770848_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000007956 111.0
HKD1_k127_1770848_6 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000005308 105.0
HKD1_k127_1770848_7 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000004349 95.0
HKD1_k127_1770848_8 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000009418 68.0
HKD1_k127_178105_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
HKD1_k127_178105_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000001112 176.0
HKD1_k127_178105_2 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000005829 68.0
HKD1_k127_178105_3 - - - - 0.0000000005077 68.0
HKD1_k127_178105_4 ketosteroid isomerase - - - 0.00000003286 64.0
HKD1_k127_180669_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 493.0
HKD1_k127_180669_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000001497 163.0
HKD1_k127_180669_2 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000002213 55.0
HKD1_k127_1833751_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.646e-205 649.0
HKD1_k127_1833751_1 Metal-dependent phosphohydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002754 273.0
HKD1_k127_1833751_2 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
HKD1_k127_1833751_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.000000000000000000000000000000000000000000003291 167.0
HKD1_k127_1833751_4 LexA DNA binding domain K01356 - 3.4.21.88 0.0000000000009374 78.0
HKD1_k127_186057_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.305e-227 712.0
HKD1_k127_186057_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 495.0
HKD1_k127_186057_2 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 428.0
HKD1_k127_186057_3 COG3668 Plasmid stabilization system protein - - - 0.000000000000000006742 84.0
HKD1_k127_186057_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000704 65.0
HKD1_k127_186057_5 PhoH-like protein K06217 - - 0.0000000001628 66.0
HKD1_k127_19119_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000004288 224.0
HKD1_k127_19119_1 PFAM Forkhead-associated protein - - - 0.000000000000000000001167 102.0
HKD1_k127_19119_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000003304 76.0
HKD1_k127_19119_3 RDD family - - - 0.00000000131 65.0
HKD1_k127_19119_4 Forkhead associated domain - - - 0.00000211 61.0
HKD1_k127_1915463_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 429.0
HKD1_k127_1915463_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 374.0
HKD1_k127_1915463_2 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000005155 169.0
HKD1_k127_1915463_3 integral membrane protein - - - 0.00000000001915 74.0
HKD1_k127_1919988_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000009665 168.0
HKD1_k127_1919988_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000002346 93.0
HKD1_k127_192290_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 433.0
HKD1_k127_192290_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002371 264.0
HKD1_k127_192290_2 O-Antigen ligase K02847 - - 0.0000000000000000000000000000003897 138.0
HKD1_k127_192290_3 SMART Tetratricopeptide domain protein - - - 0.00000009258 64.0
HKD1_k127_192290_4 Parallel beta-helix repeats - - - 0.000004427 54.0
HKD1_k127_192290_5 polysaccharide lyase family 8 domain protein K01727 GO:0005575,GO:0005576 4.2.2.1 0.000006107 59.0
HKD1_k127_1946532_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 2.305e-203 640.0
HKD1_k127_1946532_1 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 390.0
HKD1_k127_1946532_2 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000001213 207.0
HKD1_k127_1946532_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.000006978 48.0
HKD1_k127_1953434_0 Amidohydrolase family K01464 - 3.5.2.2 9.102e-200 632.0
HKD1_k127_1953434_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
HKD1_k127_1953434_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000004946 266.0
HKD1_k127_1953434_3 GTP cyclohydrolase II - - - 0.00000000000000000000000000000000000000000000000000000008247 200.0
HKD1_k127_1953434_4 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000001345 91.0
HKD1_k127_1953434_5 Domain of unknown function (DUF4440) - - - 0.00000000000001671 80.0
HKD1_k127_1954951_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 520.0
HKD1_k127_1954951_1 Polysaccharide biosynthesis/export protein - - - 0.00000000000001328 85.0
HKD1_k127_1954951_2 G-rich domain on putative tyrosine kinase - - - 0.00000004649 61.0
HKD1_k127_2035353_0 carbohydrate transport K10544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 372.0
HKD1_k127_2035353_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
HKD1_k127_2035353_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 316.0
HKD1_k127_2035353_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003791 280.0
HKD1_k127_2035353_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000186 206.0
HKD1_k127_2035353_5 ABC transporter K02056 - 3.6.3.17 0.00000000000003154 72.0
HKD1_k127_2035353_6 - - - - 0.0004003 48.0
HKD1_k127_2035926_0 Forkhead associated domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 339.0
HKD1_k127_2035926_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000002649 176.0
HKD1_k127_2035926_2 O-Antigen ligase - - - 0.000000004329 68.0
HKD1_k127_2035926_3 Domain of unknown function (DUF4190) - - - 0.0002073 50.0
HKD1_k127_2035926_4 SPTR CHU large protein - - - 0.0002602 51.0
HKD1_k127_2064306_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000002144 191.0
HKD1_k127_2064306_1 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000001485 105.0
HKD1_k127_2064306_2 - - - - 0.0000000000000000001618 90.0
HKD1_k127_207271_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 508.0
HKD1_k127_207271_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 326.0
HKD1_k127_207271_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000001554 83.0
HKD1_k127_207912_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 7.165e-265 839.0
HKD1_k127_207912_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 462.0
HKD1_k127_207912_2 DinB superfamily - - - 0.0000000000000000000000000002914 121.0
HKD1_k127_207912_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000001712 70.0
HKD1_k127_207912_4 Tetratricopeptide repeat - - - 0.00000002167 65.0
HKD1_k127_2079517_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 506.0
HKD1_k127_2079517_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 374.0
HKD1_k127_2079517_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004816 272.0
HKD1_k127_2079517_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000006246 176.0
HKD1_k127_2079517_4 Belongs to the TPP enzyme family K01637,K01652 - 2.2.1.6,4.1.3.1 0.000000003034 64.0
HKD1_k127_2089_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 490.0
HKD1_k127_2089_1 elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 497.0
HKD1_k127_2089_2 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 414.0
HKD1_k127_2089_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 327.0
HKD1_k127_2089_4 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
HKD1_k127_2089_5 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000006351 139.0
HKD1_k127_2089_6 Belongs to the dihydrofolate reductase family K00287 - 1.5.1.3 0.00000000000000000000000000000002502 131.0
HKD1_k127_2089_7 Protein of unknown function (DUF2442) - - - 0.00000000000000000009335 91.0
HKD1_k127_2107924_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 441.0
HKD1_k127_2107924_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000001388 234.0
HKD1_k127_2121649_0 ketoglutarate semialdehyde dehydrogenase K14519 - 1.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 559.0
HKD1_k127_2121649_1 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 403.0
HKD1_k127_2121649_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000001391 125.0
HKD1_k127_2128460_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 593.0
HKD1_k127_2132666_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 518.0
HKD1_k127_2132666_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000002045 173.0
HKD1_k127_2132666_2 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000002607 153.0
HKD1_k127_214785_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.361e-218 694.0
HKD1_k127_214785_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 602.0
HKD1_k127_214785_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000007502 180.0
HKD1_k127_214785_11 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000003827 172.0
HKD1_k127_214785_12 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000000000000001159 175.0
HKD1_k127_214785_13 - - - - 0.000000000000000000000000000000000000000004003 161.0
HKD1_k127_214785_14 sequence-specific DNA binding K03719 - - 0.0000000000000000000000000000000000000002165 154.0
HKD1_k127_214785_15 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000000000204 149.0
HKD1_k127_214785_16 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000455 150.0
HKD1_k127_214785_17 XRE family transcriptional regulator K21498 - - 0.0000000000000000000000000000005176 123.0
HKD1_k127_214785_18 Vitamin K epoxide reductase - - - 0.000000000001256 74.0
HKD1_k127_214785_19 - - - - 0.00000003811 61.0
HKD1_k127_214785_2 PFAM DeoC LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 563.0
HKD1_k127_214785_20 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.000004691 55.0
HKD1_k127_214785_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 542.0
HKD1_k127_214785_4 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 436.0
HKD1_k127_214785_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 430.0
HKD1_k127_214785_6 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 379.0
HKD1_k127_214785_7 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 360.0
HKD1_k127_214785_8 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000631 266.0
HKD1_k127_214785_9 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000007131 203.0
HKD1_k127_215310_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 5e-324 1010.0
HKD1_k127_215310_1 radical SAM domain protein - - - 8.799e-277 864.0
HKD1_k127_215310_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 416.0
HKD1_k127_215310_3 Voltage-dependent anion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 290.0
HKD1_k127_215310_4 Subtilase family K14645 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000003158 207.0
HKD1_k127_215310_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000004053 119.0
HKD1_k127_215310_6 Predicted membrane protein (DUF2085) - - - 0.00000000000000000007828 96.0
HKD1_k127_215310_8 - - - - 0.0000005163 55.0
HKD1_k127_2155092_0 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 509.0
HKD1_k127_2155092_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 504.0
HKD1_k127_2155092_2 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000000000008038 164.0
HKD1_k127_2155092_3 - - - - 0.0007376 51.0
HKD1_k127_2156191_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 402.0
HKD1_k127_2156191_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989,K21400 GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006464,GO:0006520,GO:0006549,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008838,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0031406,GO:0032787,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.263,3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
HKD1_k127_2156191_2 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 350.0
HKD1_k127_2156191_3 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 328.0
HKD1_k127_2156191_4 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001594 265.0
HKD1_k127_2156191_5 Superoxide dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000183 211.0
HKD1_k127_2156191_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000001932 190.0
HKD1_k127_2156191_7 Hemerythrin HHE cation binding domain - - - 0.0000000000000000003863 101.0
HKD1_k127_2156191_8 Transglycosylase associated protein - - - 0.0000000000000000003999 90.0
HKD1_k127_2156191_9 Periplasmic or secreted lipoprotein - - - 0.00000009044 65.0
HKD1_k127_2173639_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000004509 196.0
HKD1_k127_2173639_1 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate K11103 - - 0.0000000000000000000000000000000000000000000004666 168.0
HKD1_k127_2175912_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000002271 259.0
HKD1_k127_2175912_1 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000006229 151.0
HKD1_k127_2175912_2 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000004258 113.0
HKD1_k127_2177579_0 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 432.0
HKD1_k127_2177579_1 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
HKD1_k127_2177579_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
HKD1_k127_2177579_3 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000007159 233.0
HKD1_k127_2177579_4 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000001625 169.0
HKD1_k127_2177579_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000001433 137.0
HKD1_k127_2177579_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03116,K03117 - - 0.000003768 55.0
HKD1_k127_2180158_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.033e-228 720.0
HKD1_k127_2180158_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000002003 152.0
HKD1_k127_2190202_0 Carboxypeptidase regulatory-like domain - - - 8.706e-229 739.0
HKD1_k127_2190202_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD1_k127_2211816_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1109.0
HKD1_k127_2211816_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 404.0
HKD1_k127_2211816_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000006438 154.0
HKD1_k127_2211816_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000001305 94.0
HKD1_k127_2211816_2 Belongs to the ClpA ClpB family K03695,K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 400.0
HKD1_k127_2211816_3 ABC-type hemin transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 331.0
HKD1_k127_2211816_4 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 310.0
HKD1_k127_2211816_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 305.0
HKD1_k127_2211816_6 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 289.0
HKD1_k127_2211816_7 abc transporter (atp-binding protein) K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006748 282.0
HKD1_k127_2211816_8 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
HKD1_k127_2211816_9 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000001176 177.0
HKD1_k127_2215850_0 Rhs Element Vgr Protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 587.0
HKD1_k127_2215850_1 Domain of unknown function (DUF4123) - - - 0.0000000000000000000000000000000000000003511 154.0
HKD1_k127_2215850_2 ABC-2 family transporter protein K01992 - - 0.000000000000008248 75.0
HKD1_k127_2215850_3 Domain of unknown function (DUF4123) - - - 0.00000000002217 72.0
HKD1_k127_2238635_0 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000000000000006032 242.0
HKD1_k127_2238635_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000003338 218.0
HKD1_k127_2238635_2 Putative Ig domain - - - 0.0000000000000000000000000000001561 143.0
HKD1_k127_2238635_3 - - - - 0.000002375 54.0
HKD1_k127_2238635_4 SMART Tetratricopeptide - - - 0.000005188 57.0
HKD1_k127_2240344_0 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 325.0
HKD1_k127_2240344_1 PFAM Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
HKD1_k127_2240344_2 PFAM Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000001641 139.0
HKD1_k127_2240918_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 522.0
HKD1_k127_2240918_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 388.0
HKD1_k127_2240918_2 Belongs to the UPF0102 family K07460 - - 0.000000000000000461 84.0
HKD1_k127_2244764_0 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 322.0
HKD1_k127_2244764_1 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000004009 209.0
HKD1_k127_2244764_2 Subtilase family - - - 0.00000000000001423 75.0
HKD1_k127_2261699_0 Alcohol dehydrogenase GroES-associated K18369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 456.0
HKD1_k127_2261699_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 268.0
HKD1_k127_2261699_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000001556 195.0
HKD1_k127_2261699_3 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000004449 188.0
HKD1_k127_2261699_4 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000002937 162.0
HKD1_k127_2261699_5 Cyclase dehydrase - - - 0.0000000000000000001564 95.0
HKD1_k127_2299390_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1199.0
HKD1_k127_2299390_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
HKD1_k127_2299390_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000002447 102.0
HKD1_k127_2299390_11 von Willebrand factor type A domain protein K07114 - - 0.00006231 55.0
HKD1_k127_2299390_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00009347 49.0
HKD1_k127_2299390_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003865 277.0
HKD1_k127_2299390_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 264.0
HKD1_k127_2299390_4 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000006067 248.0
HKD1_k127_2299390_5 Acetyltransferase (GNAT) domain K03829 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000000000000000000002626 216.0
HKD1_k127_2299390_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000001916 160.0
HKD1_k127_2299390_7 - - - - 0.0000000000000000000000000000000002881 144.0
HKD1_k127_2299390_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000001021 123.0
HKD1_k127_2299390_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000004022 119.0
HKD1_k127_2300937_0 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 534.0
HKD1_k127_2300937_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000003849 174.0
HKD1_k127_2300937_2 Thioesterase superfamily - - - 0.000000000000000002174 90.0
HKD1_k127_2307482_0 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00001097 57.0
HKD1_k127_2307482_1 ATP-dependent protease La (LON) domain K01338 - 3.4.21.53 0.0001492 49.0
HKD1_k127_2310981_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 403.0
HKD1_k127_2310981_1 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.00000000000000000000000000000000000000000000000000005239 195.0
HKD1_k127_2310981_2 Monogalactosyldiacylglycerol (MGDG) synthase K03715 - 2.4.1.46 0.00000000000000000000000000000000002844 149.0
HKD1_k127_2310981_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000332 143.0
HKD1_k127_2310981_5 PFAM YcfA-like protein - - - 0.000000000000000001351 86.0
HKD1_k127_2331739_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 452.0
HKD1_k127_2331739_1 Alpha/beta hydrolase family K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 424.0
HKD1_k127_2331739_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 342.0
HKD1_k127_2331739_3 Domain of unknown function (DUF4919) - - - 0.000000000000000000002201 103.0
HKD1_k127_2331739_4 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000003568 92.0
HKD1_k127_2331739_5 peptidyl-tyrosine sulfation - - - 0.00000000000071 80.0
HKD1_k127_2331739_6 Domain of unknown function (DUF4386) - - - 0.00000000002712 73.0
HKD1_k127_234786_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001127 281.0
HKD1_k127_234786_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HKD1_k127_234786_2 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000004297 244.0
HKD1_k127_234786_3 Regulates arginine biosynthesis genes K03402 - - 0.0000000639 57.0
HKD1_k127_2378413_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 4.045e-208 658.0
HKD1_k127_2378413_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 307.0
HKD1_k127_2423591_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 301.0
HKD1_k127_2423591_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 293.0
HKD1_k127_2423591_2 cell redox homeostasis K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001046 272.0
HKD1_k127_2445222_0 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 557.0
HKD1_k127_2445222_1 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 510.0
HKD1_k127_2478713_0 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 454.0
HKD1_k127_2478713_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000002646 107.0
HKD1_k127_2484004_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 459.0
HKD1_k127_2484004_1 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 342.0
HKD1_k127_2484004_2 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000002129 110.0
HKD1_k127_2484004_3 ferrochelatase activity K01772 GO:0001932,GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004325,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006066,GO:0006091,GO:0006417,GO:0006446,GO:0006629,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008198,GO:0008202,GO:0008203,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009589,GO:0009605,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0010999,GO:0016020,GO:0016043,GO:0016125,GO:0016829,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019866,GO:0020037,GO:0022607,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030350,GO:0031090,GO:0031323,GO:0031326,GO:0031399,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032268,GO:0032501,GO:0032502,GO:0033013,GO:0033014,GO:0034101,GO:0034248,GO:0034377,GO:0034379,GO:0034641,GO:0042168,GO:0042325,GO:0042440,GO:0042592,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0046872,GO:0046906,GO:0046914,GO:0046984,GO:0048037,GO:0048513,GO:0048534,GO:0048583,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051246,GO:0051536,GO:0051537,GO:0051540,GO:0051606,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060255,GO:0065003,GO:0065005,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071825,GO:0071827,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0097006,GO:0097159,GO:0098771,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902652,GO:2000112 4.99.1.1,4.99.1.9 0.00000000000000000001603 93.0
HKD1_k127_25088_0 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000003752 169.0
HKD1_k127_25088_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000008862 123.0
HKD1_k127_25088_2 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000009122 60.0
HKD1_k127_2523425_0 pfam nudix - - - 0.00000000000000000000000000004855 124.0
HKD1_k127_2523425_1 multi-organism process K03195 - - 0.000000000006262 77.0
HKD1_k127_2523425_2 lysine biosynthetic process via aminoadipic acid - - - 0.000001615 60.0
HKD1_k127_2535678_0 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 8.164e-229 725.0
HKD1_k127_2535678_1 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 535.0
HKD1_k127_2535678_2 D-galactarate dehydratase Altronate K01685,K01708 - 4.2.1.42,4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 393.0
HKD1_k127_2535678_3 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 362.0
HKD1_k127_2535678_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 353.0
HKD1_k127_2535678_5 glucosamine-6-phosphate deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
HKD1_k127_2535678_6 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
HKD1_k127_2535678_7 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000004708 104.0
HKD1_k127_2535678_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000006545 75.0
HKD1_k127_2535678_9 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.000000001621 64.0
HKD1_k127_2579109_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 506.0
HKD1_k127_2579109_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000007706 148.0
HKD1_k127_2579109_2 - - - - 0.0000002301 59.0
HKD1_k127_2589173_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 324.0
HKD1_k127_2589173_1 'Xanthine and CO dehydrogenases maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 309.0
HKD1_k127_2589173_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000008481 218.0
HKD1_k127_2589173_3 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000005218 209.0
HKD1_k127_2589173_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000006741 168.0
HKD1_k127_2620631_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 566.0
HKD1_k127_2620631_1 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000003405 154.0
HKD1_k127_2620631_2 acetyltransferase K03828 - - 0.0000000000000000000000000000000000007644 144.0
HKD1_k127_2620631_3 - - - - 0.000000000000000000000000000000000006431 143.0
HKD1_k127_2633814_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 580.0
HKD1_k127_2633814_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 460.0
HKD1_k127_2633814_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 417.0
HKD1_k127_2633814_3 COG1606 ATP-utilizing enzymes of the PP-loop superfamily K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003743 258.0
HKD1_k127_2633814_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000006485 169.0
HKD1_k127_2633814_5 Aminotransferase class-V - - - 0.00000000000000001902 87.0
HKD1_k127_2633814_6 Tetratricopeptide repeats - - - 0.00005781 55.0
HKD1_k127_264734_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 456.0
HKD1_k127_264734_1 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 338.0
HKD1_k127_264734_2 - - - - 0.0000000000000000000000000000000000000000000005179 173.0
HKD1_k127_2729920_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 359.0
HKD1_k127_2729920_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 350.0
HKD1_k127_2729920_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002505 282.0
HKD1_k127_2729920_3 Lipocalin-like domain - - - 0.00000000000000000000469 101.0
HKD1_k127_2729920_4 Stress responsive A/B Barrel Domain - - - 0.000000000000006313 78.0
HKD1_k127_2743959_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.007e-284 885.0
HKD1_k127_2743959_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 394.0
HKD1_k127_2743959_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 289.0
HKD1_k127_277884_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 499.0
HKD1_k127_277884_1 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 402.0
HKD1_k127_277884_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001394 183.0
HKD1_k127_2779046_0 Hydrolase - - - 2.293e-212 670.0
HKD1_k127_2779046_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000001111 250.0
HKD1_k127_2779046_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000004905 70.0
HKD1_k127_282673_0 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 556.0
HKD1_k127_282673_1 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
HKD1_k127_282673_2 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000001925 96.0
HKD1_k127_282673_3 Protein of unknown function (DUF3060) - - - 0.00003596 52.0
HKD1_k127_2827_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 543.0
HKD1_k127_2827_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 425.0
HKD1_k127_2827_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000002946 160.0
HKD1_k127_2827_3 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000002451 147.0
HKD1_k127_2827_4 Amidohydrolase family - - - 0.00000000000000272 81.0
HKD1_k127_2840323_0 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 3.593e-196 623.0
HKD1_k127_2840323_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000002058 129.0
HKD1_k127_2840323_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000008876 117.0
HKD1_k127_2842852_0 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 507.0
HKD1_k127_2842852_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000003684 113.0
HKD1_k127_2842852_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000007206 83.0
HKD1_k127_284777_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 417.0
HKD1_k127_284777_1 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000008149 168.0
HKD1_k127_284777_2 OmpA family - - - 0.000000000000000000000000000003321 132.0
HKD1_k127_284777_3 response regulator K02282 - - 0.000000000000000000000000003351 116.0
HKD1_k127_284777_4 Domain of unknown function (DUF4136) - - - 0.0005426 49.0
HKD1_k127_2849640_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 554.0
HKD1_k127_2849640_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000002817 191.0
HKD1_k127_2849640_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000008833 153.0
HKD1_k127_2849640_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000005124 125.0
HKD1_k127_2849640_4 Polymer-forming cytoskeletal - - - 0.000000000000000003482 93.0
HKD1_k127_2860539_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 1.951e-291 913.0
HKD1_k127_2860539_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 481.0
HKD1_k127_2860539_2 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 436.0
HKD1_k127_2860539_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
HKD1_k127_2860539_4 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000001897 214.0
HKD1_k127_2860539_5 Acid phosphatase homologues - - - 0.00000000000000000000000000000000001703 146.0
HKD1_k127_2860539_6 Tetratricopeptide repeat - - - 0.00000000001621 74.0
HKD1_k127_2860539_7 ResB protein required for cytochrome c K07399 - - 0.000000004203 66.0
HKD1_k127_2868296_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 427.0
HKD1_k127_2868296_1 - - - - 0.00000000000000000000000000000000000000008794 154.0
HKD1_k127_2868296_2 - - - - 0.0000000000000008973 83.0
HKD1_k127_2884117_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
HKD1_k127_2884117_1 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000002363 199.0
HKD1_k127_2884117_2 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000004816 194.0
HKD1_k127_2884117_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000001634 127.0
HKD1_k127_2977342_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000003095 242.0
HKD1_k127_2977342_1 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000103 175.0
HKD1_k127_2977342_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.22 0.0000000000000000000000000000000000000000001771 168.0
HKD1_k127_2977342_3 metallopeptidase activity - - - 0.0000000000000000000002871 105.0
HKD1_k127_2977342_4 Ribosomal protein L11 methyltransferase (PrmA) K11434 - 2.1.1.319 0.000000000000001469 88.0
HKD1_k127_300654_0 ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 379.0
HKD1_k127_300654_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000007939 210.0
HKD1_k127_300654_2 Fibronectin-binding protein - - - 0.00000000000000000000000000000000000000000000000001309 198.0
HKD1_k127_300654_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000001311 200.0
HKD1_k127_300654_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000001777 141.0
HKD1_k127_300654_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000256 103.0
HKD1_k127_300654_6 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000001761 95.0
HKD1_k127_300654_7 RDD family - - - 0.000009481 58.0
HKD1_k127_3029677_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 514.0
HKD1_k127_3029677_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 389.0
HKD1_k127_3029677_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000003197 185.0
HKD1_k127_3029677_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000002661 186.0
HKD1_k127_3029677_4 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000008571 164.0
HKD1_k127_3029677_5 Domain of unknown function (DUF4440) - - - 0.0000000000000000001802 94.0
HKD1_k127_3029677_6 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000006576 63.0
HKD1_k127_3029903_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006201 275.0
HKD1_k127_3029903_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000004382 130.0
HKD1_k127_3029903_2 Iron permease FTR1 family K07243 - - 0.00007975 52.0
HKD1_k127_3034386_0 - - - - 0.00000000000000000000000000000000000002633 160.0
HKD1_k127_3034386_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000005025 134.0
HKD1_k127_3034386_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.00002923 55.0
HKD1_k127_3034386_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0008178 50.0
HKD1_k127_3052705_1 TPR Domain containing protein K12600 - - 0.000000000000001107 90.0
HKD1_k127_3052705_3 translation factor activity, non-nucleic acid binding K20804 GO:0000003,GO:0000209,GO:0001654,GO:0001709,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002682,GO:0002683,GO:0003002,GO:0003006,GO:0003008,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007398,GO:0007399,GO:0007422,GO:0007423,GO:0007444,GO:0007472,GO:0007476,GO:0007498,GO:0007552,GO:0007560,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008052,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0008289,GO:0008356,GO:0008593,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009966,GO:0009967,GO:0009987,GO:0010160,GO:0010646,GO:0010647,GO:0016020,GO:0016043,GO:0016360,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019827,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0023051,GO:0023056,GO:0030154,GO:0030707,GO:0030718,GO:0030855,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0033036,GO:0035091,GO:0035107,GO:0035114,GO:0035120,GO:0035203,GO:0035204,GO:0035220,GO:0035239,GO:0035295,GO:0036211,GO:0042478,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045165,GO:0045314,GO:0045595,GO:0045596,GO:0045610,GO:0045611,GO:0045613,GO:0045614,GO:0045664,GO:0045747,GO:0046532,GO:0046872,GO:0046914,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048580,GO:0048581,GO:0048583,GO:0048584,GO:0048609,GO:0048645,GO:0048646,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048749,GO:0048856,GO:0048859,GO:0048869,GO:0050767,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0051093,GO:0051179,GO:0051239,GO:0051241,GO:0051259,GO:0051260,GO:0051301,GO:0051704,GO:0051960,GO:0060284,GO:0060429,GO:0060562,GO:0060581,GO:0060582,GO:0061630,GO:0061659,GO:0065003,GO:0065007,GO:0070647,GO:0071704,GO:0071840,GO:0071944,GO:0098727,GO:0140096,GO:1901564,GO:1901981,GO:1903706,GO:1903707,GO:2000026,GO:2000027 2.3.2.31 0.0001325 51.0
HKD1_k127_3054817_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.674e-259 807.0
HKD1_k127_3054817_1 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 415.0
HKD1_k127_3054817_2 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001668 258.0
HKD1_k127_3054817_3 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000004511 64.0
HKD1_k127_3060650_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 389.0
HKD1_k127_3060650_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 363.0
HKD1_k127_3060650_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 310.0
HKD1_k127_3060650_3 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 302.0
HKD1_k127_3060650_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001012 283.0
HKD1_k127_3060650_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000007912 123.0
HKD1_k127_3062061_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.614e-249 775.0
HKD1_k127_3062061_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 623.0
HKD1_k127_3062061_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000001057 203.0
HKD1_k127_3062061_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000003181 133.0
HKD1_k127_3062288_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 369.0
HKD1_k127_3062288_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000003021 180.0
HKD1_k127_3062288_2 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000004535 151.0
HKD1_k127_3062288_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000004113 132.0
HKD1_k127_3064231_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 3.223e-260 812.0
HKD1_k127_3064231_1 of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000002398 264.0
HKD1_k127_3064231_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001054 163.0
HKD1_k127_3064231_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000308 104.0
HKD1_k127_3064231_4 Domain of unknown function (DUF1844) - - - 0.000000000002109 74.0
HKD1_k127_3078055_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002095 161.0
HKD1_k127_3091937_0 FAD dependent oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 566.0
HKD1_k127_3091937_1 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000003288 201.0
HKD1_k127_3091937_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000001386 168.0
HKD1_k127_3111639_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 443.0
HKD1_k127_3111639_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 459.0
HKD1_k127_3111639_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000001167 119.0
HKD1_k127_3111639_11 - - - - 0.000000000000000000000533 108.0
HKD1_k127_3111639_12 oxidoreductase activity K08282,K16260 - 2.7.11.1 0.00000000000009885 81.0
HKD1_k127_3111639_13 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000002512 63.0
HKD1_k127_3111639_14 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.000000143 62.0
HKD1_k127_3111639_15 - - - - 0.0001546 46.0
HKD1_k127_3111639_2 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002033 281.0
HKD1_k127_3111639_3 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000003461 262.0
HKD1_k127_3111639_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001238 254.0
HKD1_k127_3111639_5 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
HKD1_k127_3111639_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000002964 210.0
HKD1_k127_3111639_7 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000001714 191.0
HKD1_k127_3111639_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000003814 171.0
HKD1_k127_3111639_9 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000000000000000000000000005777 172.0
HKD1_k127_3111888_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1456.0
HKD1_k127_3111888_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 295.0
HKD1_k127_3111888_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000007298 210.0
HKD1_k127_3111888_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000002269 205.0
HKD1_k127_3111888_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000007555 168.0
HKD1_k127_3111888_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000005858 151.0
HKD1_k127_3111888_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000002258 108.0
HKD1_k127_3111888_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000003944 81.0
HKD1_k127_3121720_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.603e-278 877.0
HKD1_k127_3121720_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 512.0
HKD1_k127_3121720_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HKD1_k127_3121720_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000007584 212.0
HKD1_k127_3121720_4 PFAM regulatory protein TetR K13770 - - 0.0000000000000000000000000000000000000000000002676 174.0
HKD1_k127_3121720_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000001436 92.0
HKD1_k127_3121720_6 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000003455 96.0
HKD1_k127_3125991_0 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000005326 218.0
HKD1_k127_3125991_1 DoxX K15977 - - 0.00000000000000000000000000000001141 135.0
HKD1_k127_3125991_2 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000001984 91.0
HKD1_k127_3127062_0 TonB-dependent receptor - - - 2.758e-213 700.0
HKD1_k127_3127062_1 Carboxypeptidase regulatory-like domain - - - 6.75e-207 674.0
HKD1_k127_3157250_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1046.0
HKD1_k127_3157250_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.863e-240 753.0
HKD1_k127_3157250_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000002553 170.0
HKD1_k127_3157250_3 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000002723 102.0
HKD1_k127_3183205_0 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 581.0
HKD1_k127_3183205_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 490.0
HKD1_k127_3183205_2 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 488.0
HKD1_k127_3183205_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 440.0
HKD1_k127_3183205_4 Biotin-requiring enzyme - - - 0.000000000000000000002084 100.0
HKD1_k127_3183205_5 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000007219 55.0
HKD1_k127_3183205_6 - - - - 0.0000707 51.0
HKD1_k127_31976_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.652e-214 677.0
HKD1_k127_31976_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001224 281.0
HKD1_k127_3241497_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 430.0
HKD1_k127_3241497_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 387.0
HKD1_k127_3241497_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
HKD1_k127_3241497_3 FR47-like protein - - - 0.000000000000000000000000000000000000001067 153.0
HKD1_k127_3241497_4 COG1278 Cold shock proteins K03704 - - 0.0000000000000000000000009379 105.0
HKD1_k127_3241497_5 Glycosyl hydrolase-like 10 - - - 0.0000000000000000547 85.0
HKD1_k127_3241497_6 - - - - 0.0000000000000001753 83.0
HKD1_k127_3241497_7 Tetratricopeptide repeat - - - 0.0005873 52.0
HKD1_k127_3277095_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.511e-212 678.0
HKD1_k127_3277095_1 PhoQ Sensor K07640 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007337 281.0
HKD1_k127_3277095_2 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.0000000000000000000000000000000000000000000000000000009653 207.0
HKD1_k127_3277095_3 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000001154 109.0
HKD1_k127_3277095_4 - - - - 0.000000000000000001209 90.0
HKD1_k127_3278451_0 phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 550.0
HKD1_k127_3278451_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000825 193.0
HKD1_k127_3278451_2 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000001459 99.0
HKD1_k127_3278451_3 general stress protein - - - 0.000000000000000001167 91.0
HKD1_k127_3278451_4 tigr00255 - - - 0.000000002441 58.0
HKD1_k127_3297760_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 550.0
HKD1_k127_3297760_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 372.0
HKD1_k127_3297760_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000003276 130.0
HKD1_k127_3297760_3 Methyltransferase FkbM domain - - - 0.0000000000000000000000000008583 124.0
HKD1_k127_3297760_4 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000000000005919 108.0
HKD1_k127_3297760_5 Glycosyl transferase group 1 - - - 0.000000000000000000002295 107.0
HKD1_k127_33249_0 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 410.0
HKD1_k127_33249_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 357.0
HKD1_k127_33249_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000007889 50.0
HKD1_k127_3326081_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 4.307e-223 728.0
HKD1_k127_3326081_1 PFAM ABC transporter related K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 559.0
HKD1_k127_3326081_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 544.0
HKD1_k127_3326081_3 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 539.0
HKD1_k127_3326081_4 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 482.0
HKD1_k127_3326081_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 439.0
HKD1_k127_3326081_6 Penicillinase repressor - - - 0.000000000000000000000002779 107.0
HKD1_k127_3326081_7 - - - - 0.0000000000000000000001584 106.0
HKD1_k127_3326081_8 TIGRFAM TonB K03832 - - 0.0000001768 64.0
HKD1_k127_3326081_9 metalloendopeptidase activity K03799 - - 0.0000004281 61.0
HKD1_k127_3365098_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 598.0
HKD1_k127_3365098_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 272.0
HKD1_k127_3365098_2 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
HKD1_k127_3365098_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000899 145.0
HKD1_k127_3365098_4 PFAM SNARE associated Golgi protein K03975 - - 0.000000009379 66.0
HKD1_k127_3421462_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007871 283.0
HKD1_k127_3421462_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000001738 97.0
HKD1_k127_3421462_3 - - - - 0.000000000003607 74.0
HKD1_k127_3428577_0 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 1.976e-302 947.0
HKD1_k127_3428577_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 565.0
HKD1_k127_3428577_2 Oligogalacturonate lyase K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 437.0
HKD1_k127_3428577_3 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 418.0
HKD1_k127_3428577_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 413.0
HKD1_k127_3428577_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 322.0
HKD1_k127_3428577_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
HKD1_k127_3428577_7 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000001829 166.0
HKD1_k127_3428577_8 L-arabinokinase-like K12446 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009506,GO:0009702,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0030054,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0055044,GO:0071704 2.7.1.46 0.000000000002251 68.0
HKD1_k127_3438961_0 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002403 304.0
HKD1_k127_3438961_1 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000000000000002428 227.0
HKD1_k127_3438961_2 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000008456 72.0
HKD1_k127_3443752_0 Histidine kinase K02480,K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 455.0
HKD1_k127_3443752_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000001209 187.0
HKD1_k127_3443752_2 PFAM Hemolysin-type calcium-binding repeat (2 copies) K20276 - - 0.00000000000000001225 87.0
HKD1_k127_3443752_3 helix_turn_helix, Lux Regulon - - - 0.000000000000003668 80.0
HKD1_k127_3447244_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000001019 208.0
HKD1_k127_3447244_1 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000001092 191.0
HKD1_k127_3447244_2 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.0000000000000000000000000000000000000518 147.0
HKD1_k127_3447244_3 ResB-like family K07399 - - 0.00000000000000000000000000000504 136.0
HKD1_k127_3447244_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000002258 115.0
HKD1_k127_3447244_5 Penicillin amidase - - - 0.00000000000000000002602 100.0
HKD1_k127_3481277_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
HKD1_k127_3481277_1 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000001598 175.0
HKD1_k127_3481277_2 Glycosyltransferase Family 4 K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000006536 104.0
HKD1_k127_3481277_3 Glycosyltransferase Family 4 K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000001513 96.0
HKD1_k127_3481277_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000003699 72.0
HKD1_k127_3481277_5 Hep Hag repeat protein K21449 - - 0.0000002997 55.0
HKD1_k127_34933_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005649 276.0
HKD1_k127_34933_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000002667 190.0
HKD1_k127_34933_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000001409 179.0
HKD1_k127_34933_3 Zn peptidase K21686 - - 0.0000000000000000000000002375 114.0
HKD1_k127_34933_5 - - - - 0.00007752 54.0
HKD1_k127_34933_6 CarboxypepD_reg-like domain - - - 0.0001873 50.0
HKD1_k127_3493748_0 hydrolase family 92 - - - 1.713e-305 970.0
HKD1_k127_3493748_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 475.0
HKD1_k127_3493748_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
HKD1_k127_3493748_3 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000373 177.0
HKD1_k127_3508378_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 379.0
HKD1_k127_3508378_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 342.0
HKD1_k127_3508378_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 344.0
HKD1_k127_3508378_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000002344 225.0
HKD1_k127_3508378_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002616 208.0
HKD1_k127_3508378_5 domain protein - - - 0.000000000000000000000000000000000000533 158.0
HKD1_k127_3508378_6 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000002307 106.0
HKD1_k127_3508378_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000002197 68.0
HKD1_k127_3508378_8 Protein of unknown function (DUF433) - - - 0.0002279 49.0
HKD1_k127_3536433_0 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003755 273.0
HKD1_k127_3536433_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007654 254.0
HKD1_k127_3536433_2 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000005939 171.0
HKD1_k127_3536433_3 Helix-hairpin-helix class 2 (Pol1 family) motifs K02335 - 2.7.7.7 0.0000000000000000000000000000000000001576 144.0
HKD1_k127_356116_0 Hydrolase CocE NonD family - - - 9.065e-315 975.0
HKD1_k127_356116_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.078e-265 824.0
HKD1_k127_356116_2 Domain of unknown function (DUF5118) - - - 9.738e-245 784.0
HKD1_k127_356116_3 Berberine and berberine like - - - 6.841e-199 629.0
HKD1_k127_356116_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 514.0
HKD1_k127_356116_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004399 266.0
HKD1_k127_356116_6 YtxH-like protein - - - 0.000000007052 63.0
HKD1_k127_356116_7 - - - - 0.0000002593 59.0
HKD1_k127_3590842_0 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 495.0
HKD1_k127_3590842_1 OmpA family - - - 0.000000000000000000000002552 115.0
HKD1_k127_3590842_2 von Willebrand factor, type A - - - 0.0000001252 58.0
HKD1_k127_3629097_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003439 264.0
HKD1_k127_3629097_1 Universal stress protein family - - - 0.00000000000000001413 88.0
HKD1_k127_3629097_2 Pfam:N_methyl_2 - - - 0.000005543 54.0
HKD1_k127_3699054_0 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 577.0
HKD1_k127_3699054_1 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000002153 219.0
HKD1_k127_3699054_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000006523 185.0
HKD1_k127_3699054_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000001646 126.0
HKD1_k127_37170_0 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 555.0
HKD1_k127_37170_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000006504 182.0
HKD1_k127_37170_2 - - - - 0.0000000000000000001944 90.0
HKD1_k127_37170_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000001989 65.0
HKD1_k127_3718358_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
HKD1_k127_3718358_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005833 277.0
HKD1_k127_3718358_2 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.000000000000000000000000000000000000000000000000000002788 196.0
HKD1_k127_3718358_3 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000007777 120.0
HKD1_k127_3718358_4 Belongs to the ompA family - - - 0.00000000000000000000000521 115.0
HKD1_k127_3718358_5 Putative regulatory protein - - - 0.00000000000000000003964 93.0
HKD1_k127_3718358_6 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000004056 99.0
HKD1_k127_3719178_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 390.0
HKD1_k127_3719178_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000118 172.0
HKD1_k127_3719178_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000005157 68.0
HKD1_k127_3726545_0 Cytochrome C and Quinol oxidase polypeptide I - - - 1.111e-311 970.0
HKD1_k127_3726545_1 CHASE3 domain - - - 4.882e-223 709.0
HKD1_k127_3726545_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000005496 151.0
HKD1_k127_3726545_11 Protein of unknown function (DUF2934) - - - 0.000000000000000000003563 100.0
HKD1_k127_3726545_12 Universal stress protein family - - - 0.00000000000000000002378 96.0
HKD1_k127_3726545_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.873e-198 633.0
HKD1_k127_3726545_3 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 583.0
HKD1_k127_3726545_4 glutamate-1-semialdehyde 2,1-aminomutase activity K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 514.0
HKD1_k127_3726545_5 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 437.0
HKD1_k127_3726545_6 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 381.0
HKD1_k127_3726545_7 type VI secretion protein K11900,K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 374.0
HKD1_k127_3726545_8 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000002288 256.0
HKD1_k127_3726545_9 Erythromycin esterase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001232 243.0
HKD1_k127_3774827_0 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000003654 220.0
HKD1_k127_3774827_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000009457 152.0
HKD1_k127_3774827_2 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.00000008266 63.0
HKD1_k127_3774827_3 Parallel beta-helix repeats - - - 0.00007403 48.0
HKD1_k127_3794018_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
HKD1_k127_3794018_1 Pilus assembly protein, PilO K02664 - - 0.0004594 51.0
HKD1_k127_3812269_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 553.0
HKD1_k127_3812269_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 362.0
HKD1_k127_3812269_2 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
HKD1_k127_3812269_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000002431 129.0
HKD1_k127_3812269_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001486 104.0
HKD1_k127_3812269_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000006938 87.0
HKD1_k127_3842608_0 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 420.0
HKD1_k127_3842608_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 292.0
HKD1_k127_3842608_2 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005865 282.0
HKD1_k127_3842608_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002496 253.0
HKD1_k127_3842608_4 Putative methyltransferase K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000004572 231.0
HKD1_k127_3842608_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000001486 157.0
HKD1_k127_3842608_6 - - - - 0.000000000000000000000000001025 124.0
HKD1_k127_3842608_7 Rhomboid family - - - 0.00000000000000000000002538 110.0
HKD1_k127_3842608_8 von Willebrand factor (vWF) type A domain - - - 0.00009527 48.0
HKD1_k127_3851468_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009944 282.0
HKD1_k127_3851468_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000004745 183.0
HKD1_k127_3851468_2 metallopeptidase activity K03592 - - 0.00000000000000678 89.0
HKD1_k127_3934930_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 464.0
HKD1_k127_3934930_1 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 344.0
HKD1_k127_3934930_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002124 248.0
HKD1_k127_3934930_3 Histidine kinase K07710 - 2.7.13.3 0.00000000000568 79.0
HKD1_k127_3946707_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 376.0
HKD1_k127_3946707_1 Belongs to the glycosyl hydrolase 1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 287.0
HKD1_k127_3946707_2 Fumarate reductase flavoprotein C-term K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 269.0
HKD1_k127_3946707_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000003122 245.0
HKD1_k127_3946707_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000001342 170.0
HKD1_k127_395904_0 Peptidase family M3 K01392 - 3.4.24.15 1.199e-213 682.0
HKD1_k127_395904_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001881 269.0
HKD1_k127_395904_2 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000517 231.0
HKD1_k127_395904_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000005 214.0
HKD1_k127_395904_4 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.00000000000000000000000000000002469 129.0
HKD1_k127_395904_5 Domain of unknown function (DUF4440) - - - 0.00000000000000000000002916 104.0
HKD1_k127_4022415_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.959e-250 785.0
HKD1_k127_4022415_1 Tricorn protease C1 domain K08676 - - 0.00000000000001078 74.0
HKD1_k127_4031115_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000006628 231.0
HKD1_k127_4031115_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000002574 164.0
HKD1_k127_4031115_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000002798 162.0
HKD1_k127_4031115_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000008456 151.0
HKD1_k127_4031115_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000001977 117.0
HKD1_k127_4031115_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000005876 125.0
HKD1_k127_4031115_6 OmpA family - - - 0.0000000000000000000000001171 119.0
HKD1_k127_4034814_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 381.0
HKD1_k127_4034814_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000001394 183.0
HKD1_k127_4034814_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000001974 171.0
HKD1_k127_4034814_3 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000006208 170.0
HKD1_k127_4034814_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.00004567 47.0
HKD1_k127_4047878_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 352.0
HKD1_k127_4047878_1 DoxX - - - 0.0000000000000000000000000000000000000000000003727 176.0
HKD1_k127_4047878_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000003603 167.0
HKD1_k127_4047878_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000002265 147.0
HKD1_k127_4047878_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000008493 125.0
HKD1_k127_4053322_0 ChrR Cupin-like domain - - - 0.000000000000000000000000002331 117.0
HKD1_k127_4056906_0 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 439.0
HKD1_k127_4056906_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 317.0
HKD1_k127_4056906_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 303.0
HKD1_k127_4104785_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
HKD1_k127_4104785_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 377.0
HKD1_k127_4104785_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000001815 179.0
HKD1_k127_4104785_3 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000002242 142.0
HKD1_k127_4104785_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000003752 143.0
HKD1_k127_4104785_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000002205 106.0
HKD1_k127_4104785_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000003218 84.0
HKD1_k127_4104785_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000004319 74.0
HKD1_k127_4123122_0 Tricorn protease C1 domain K08676 - - 0.0 1121.0
HKD1_k127_4123122_1 TonB dependent receptor - - - 0.000000002007 69.0
HKD1_k127_4138223_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 445.0
HKD1_k127_4138223_1 Iron-regulated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002134 252.0
HKD1_k127_4138223_2 - - - - 0.0000000000000000000000000000000000000000000000000000001711 200.0
HKD1_k127_4138223_3 Iron-regulated protein - - - 0.0000000000000000000000000000000923 128.0
HKD1_k127_4140851_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 473.0
HKD1_k127_4140851_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 440.0
HKD1_k127_4140851_2 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000001743 179.0
HKD1_k127_4140851_3 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000003729 106.0
HKD1_k127_41435_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 365.0
HKD1_k127_41435_1 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 302.0
HKD1_k127_41435_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003991 229.0
HKD1_k127_41435_3 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000568 218.0
HKD1_k127_41435_4 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.00000000000006329 73.0
HKD1_k127_41435_5 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000003106 59.0
HKD1_k127_4143691_0 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 278.0
HKD1_k127_4143691_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000001602 209.0
HKD1_k127_4143691_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000005168 217.0
HKD1_k127_4143691_3 TIGR02453 family - - - 0.0000000000000000000000000000000000000000000000000000000402 203.0
HKD1_k127_4143691_4 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000003961 176.0
HKD1_k127_4143691_5 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000002633 169.0
HKD1_k127_4143691_6 Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000004868 151.0
HKD1_k127_4143691_7 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.00000000000000000004362 93.0
HKD1_k127_4184564_0 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 598.0
HKD1_k127_4184564_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 338.0
HKD1_k127_4184564_2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.0000568 48.0
HKD1_k127_4184564_3 transcriptional regulator, ArsR family - - - 0.0009183 48.0
HKD1_k127_4212317_0 Carboxypeptidase regulatory-like domain - - - 1.86e-243 781.0
HKD1_k127_4212317_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 370.0
HKD1_k127_4212474_0 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 446.0
HKD1_k127_4212474_1 chlorophyll binding - - - 0.00000000000000000000000000000000000000008053 169.0
HKD1_k127_4212474_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000171 114.0
HKD1_k127_4212474_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000001364 102.0
HKD1_k127_4221_0 Psort location CytoplasmicMembrane, score 10.00 K02445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 507.0
HKD1_k127_4221_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000003299 121.0
HKD1_k127_4221_2 - - - - 0.000003879 54.0
HKD1_k127_4221947_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 348.0
HKD1_k127_4221947_1 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 258.0
HKD1_k127_4221947_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000001326 176.0
HKD1_k127_4221947_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000003166 109.0
HKD1_k127_4223394_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 347.0
HKD1_k127_4223394_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 347.0
HKD1_k127_4223394_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
HKD1_k127_4223394_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000001241 154.0
HKD1_k127_4240694_0 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 352.0
HKD1_k127_4240694_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 334.0
HKD1_k127_4240694_10 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000003445 99.0
HKD1_k127_4240694_11 TPR repeat - - - 0.000000002104 68.0
HKD1_k127_4240694_12 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000002943 53.0
HKD1_k127_4240694_13 Recombinase zinc beta ribbon domain - - - 0.000008878 51.0
HKD1_k127_4240694_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
HKD1_k127_4240694_3 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000009564 224.0
HKD1_k127_4240694_4 LemA family K03744 - - 0.000000000000000000000000000000000000000005469 162.0
HKD1_k127_4240694_5 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000001326 144.0
HKD1_k127_4240694_6 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000005088 134.0
HKD1_k127_4240694_7 BMC - - - 0.0000000000000000000000000000000006397 132.0
HKD1_k127_4240694_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000000000001004 128.0
HKD1_k127_4240694_9 TPM domain K06872 - - 0.00000000000000000000007544 110.0
HKD1_k127_424429_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000003088 150.0
HKD1_k127_424429_1 AntiSigma factor - - - 0.00001582 54.0
HKD1_k127_424429_2 Polymer-forming cytoskeletal - - - 0.00009002 54.0
HKD1_k127_4260522_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
HKD1_k127_4260522_1 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000003016 164.0
HKD1_k127_4260522_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000007085 55.0
HKD1_k127_4264582_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 331.0
HKD1_k127_4264582_1 Transcriptional regulator - - - 0.00000000015 67.0
HKD1_k127_4264582_2 - - - - 0.00000002573 58.0
HKD1_k127_4275924_0 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 483.0
HKD1_k127_4275924_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 362.0
HKD1_k127_4275924_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000268 228.0
HKD1_k127_4275924_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000003183 179.0
HKD1_k127_4277046_0 Phosphate acyltransferases K01897 - 6.2.1.3 7.08e-232 746.0
HKD1_k127_4277046_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 501.0
HKD1_k127_4277046_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 411.0
HKD1_k127_4277046_3 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 387.0
HKD1_k127_4277046_4 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 361.0
HKD1_k127_4277046_5 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 333.0
HKD1_k127_4277046_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000001829 101.0
HKD1_k127_4281070_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 565.0
HKD1_k127_4281070_1 Male sterility protein K02473 - 5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 351.0
HKD1_k127_4281070_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HKD1_k127_4281070_3 Periplasmic binding protein domain K02058,K10543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 321.0
HKD1_k127_4281070_4 transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000002474 226.0
HKD1_k127_4281070_5 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000006562 119.0
HKD1_k127_4286051_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 472.0
HKD1_k127_4286051_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000008353 231.0
HKD1_k127_4286051_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000003354 86.0
HKD1_k127_4286051_3 - - - - 0.0000000000002571 79.0
HKD1_k127_4287356_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 559.0
HKD1_k127_4287356_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 509.0
HKD1_k127_4287356_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001059 256.0
HKD1_k127_4299758_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 311.0
HKD1_k127_4299758_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000001474 201.0
HKD1_k127_4299758_2 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000002405 99.0
HKD1_k127_4301909_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 599.0
HKD1_k127_4301909_1 FAD linked oxidase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 433.0
HKD1_k127_4301909_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 422.0
HKD1_k127_4301909_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 372.0
HKD1_k127_4301909_4 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 316.0
HKD1_k127_4301909_5 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 299.0
HKD1_k127_4301909_6 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000002265 219.0
HKD1_k127_4301909_7 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000009709 197.0
HKD1_k127_4301909_8 DinB superfamily - - - 0.000000000000000000000000000000001764 135.0
HKD1_k127_4301909_9 - - - - 0.000000000000000000000000000000004862 131.0
HKD1_k127_431350_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 352.0
HKD1_k127_431350_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000001414 201.0
HKD1_k127_43331_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 469.0
HKD1_k127_43331_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 260.0
HKD1_k127_43331_2 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000000000000003695 149.0
HKD1_k127_43331_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0008150,GO:0040007 - 0.000008844 51.0
HKD1_k127_436058_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000007163 269.0
HKD1_k127_436058_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645,K17734 - - 0.000000000000000000000000000000000000000000000000288 194.0
HKD1_k127_436058_2 domain, Protein - - - 0.00000000000000000001332 108.0
HKD1_k127_4373553_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000002407 240.0
HKD1_k127_4373553_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000001973 104.0
HKD1_k127_4373553_3 Fibronectin type 3 domain - - - 0.0004705 50.0
HKD1_k127_439975_0 cystathionine gamma-synthase activity K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 489.0
HKD1_k127_439975_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 382.0
HKD1_k127_439975_2 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 318.0
HKD1_k127_439975_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000004957 57.0
HKD1_k127_4424273_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 597.0
HKD1_k127_4424273_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 477.0
HKD1_k127_4424273_2 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000085 284.0
HKD1_k127_4424273_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002238 255.0
HKD1_k127_4424273_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003143 197.0
HKD1_k127_4424273_5 - - - - 0.00000000000000000000003748 101.0
HKD1_k127_4429032_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.463e-232 741.0
HKD1_k127_4429032_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 568.0
HKD1_k127_4429032_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000003647 196.0
HKD1_k127_4429032_11 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000001846 171.0
HKD1_k127_4429032_12 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000104 114.0
HKD1_k127_4429032_13 - - - - 0.00000000004502 73.0
HKD1_k127_4429032_14 PBS lyase K22221 - - 0.0005664 51.0
HKD1_k127_4429032_2 Sulfatase maturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 519.0
HKD1_k127_4429032_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 409.0
HKD1_k127_4429032_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
HKD1_k127_4429032_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 342.0
HKD1_k127_4429032_6 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005646 287.0
HKD1_k127_4429032_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000007932 235.0
HKD1_k127_4429032_8 DSHCT - - - 0.0000000000000000000000000000000000000000000000000000000000008509 233.0
HKD1_k127_4429032_9 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000001198 214.0
HKD1_k127_4438881_0 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 470.0
HKD1_k127_4438881_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 349.0
HKD1_k127_4438881_10 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000007941 117.0
HKD1_k127_4438881_11 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001475 94.0
HKD1_k127_4438881_13 YGGT family K02221 - - 0.000002371 57.0
HKD1_k127_4438881_2 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 325.0
HKD1_k127_4438881_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001797 239.0
HKD1_k127_4438881_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000006589 220.0
HKD1_k127_4438881_5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.00000000000000000000000000000000000000000000003426 181.0
HKD1_k127_4438881_6 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000711 171.0
HKD1_k127_4438881_7 response regulator - - - 0.0000000000000000000000000000000000000000007314 161.0
HKD1_k127_4438881_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001048 145.0
HKD1_k127_4438881_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000002406 136.0
HKD1_k127_4502615_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 595.0
HKD1_k127_4502615_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 307.0
HKD1_k127_4502615_3 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 261.0
HKD1_k127_4502615_4 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002641 259.0
HKD1_k127_4502615_6 self proteolysis - - - 0.00000005293 65.0
HKD1_k127_4518612_0 Smr domain - - - 0.0000000000000000000000001462 110.0
HKD1_k127_4553047_0 Uncharacterized protein family (UPF0051) K09014 - - 1.071e-202 635.0
HKD1_k127_4553047_1 Transcriptional regulator - - - 0.00000000000000000000000001226 115.0
HKD1_k127_4560960_0 IPT/TIG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002461 260.0
HKD1_k127_4560960_1 RHS Repeat - - - 0.00000000000000000000003893 111.0
HKD1_k127_4594612_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000004911 162.0
HKD1_k127_4594612_1 peptidyl-tyrosine sulfation - - - 0.00000000000007679 81.0
HKD1_k127_4594612_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.0000000002481 61.0
HKD1_k127_463278_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002342 309.0
HKD1_k127_463278_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 260.0
HKD1_k127_463278_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000009163 243.0
HKD1_k127_463278_3 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000006379 170.0
HKD1_k127_464484_0 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 472.0
HKD1_k127_464484_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000001198 220.0
HKD1_k127_464484_2 transcriptional regulator RpiR family - - - 0.0000000000000000000007918 107.0
HKD1_k127_464484_3 sequence-specific DNA binding - - - 0.00000001819 63.0
HKD1_k127_4662598_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
HKD1_k127_4662598_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002093 280.0
HKD1_k127_4662598_2 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000004471 190.0
HKD1_k127_4712248_0 PFAM Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 485.0
HKD1_k127_4712248_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
HKD1_k127_4712248_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009626 242.0
HKD1_k127_4712248_3 - - - - 0.0000000000000000000000000000000000000000000000003719 187.0
HKD1_k127_4712248_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000001446 181.0
HKD1_k127_4712248_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000001043 139.0
HKD1_k127_4753799_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008947 239.0
HKD1_k127_4753799_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000001198 201.0
HKD1_k127_4753799_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000008285 130.0
HKD1_k127_478301_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 359.0
HKD1_k127_478301_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000002069 117.0
HKD1_k127_4789806_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 482.0
HKD1_k127_4789806_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
HKD1_k127_4789806_2 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000002037 211.0
HKD1_k127_4789806_3 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000859 167.0
HKD1_k127_4789806_4 peptidyl-tyrosine sulfation - - - 0.00000000001221 77.0
HKD1_k127_4789806_5 isomerase activity K06998 - 5.3.3.17 0.0000005097 53.0
HKD1_k127_4851945_0 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003244 245.0
HKD1_k127_4851945_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
HKD1_k127_4851945_2 - - - - 0.00000000000000000000000000000000000000000000000001512 193.0
HKD1_k127_4851945_3 YwiC-like protein - - - 0.0000000000000000000000000000000000002949 151.0
HKD1_k127_4851945_4 - - - - 0.000000000000000000001048 100.0
HKD1_k127_4851945_5 oxidoreductase activity - - - 0.0000000000000000004475 94.0
HKD1_k127_4855924_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 558.0
HKD1_k127_4855924_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000005839 106.0
HKD1_k127_4855924_2 repeat-containing protein - - - 0.0004695 54.0
HKD1_k127_4930009_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 463.0
HKD1_k127_4930009_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000002484 176.0
HKD1_k127_4930009_2 Antibiotic biosynthesis monooxygenase - - - 0.00000000808 63.0
HKD1_k127_497633_0 Metalloenzyme superfamily K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 440.0
HKD1_k127_497633_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
HKD1_k127_497633_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 345.0
HKD1_k127_497633_3 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 342.0
HKD1_k127_497633_4 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000003068 272.0
HKD1_k127_497633_5 - - - - 0.00000000000000000000000000000000005256 138.0
HKD1_k127_497633_6 PFAM Phosphoribosyltransferase - - - 0.000000000000000000006974 96.0
HKD1_k127_5040307_0 general secretion pathway protein K02456 - - 0.00000000000000000000006606 107.0
HKD1_k127_5040307_1 Pfam:N_methyl_2 K02456 - - 0.000000000000000007538 86.0
HKD1_k127_5040307_2 Secretin and TonB N terminus short domain K02453 - - 0.0000000000000007301 91.0
HKD1_k127_5044076_0 PFAM Uncharacterised BCR, COG1649 K01179,K04618,K07346,K12685,K17734 - 1.1.3.9,3.2.1.4 0.00000000001599 74.0
HKD1_k127_5044076_1 Pilus assembly protein PilX K02673 - - 0.00003903 56.0
HKD1_k127_504732_0 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 267.0
HKD1_k127_504732_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000001728 242.0
HKD1_k127_504732_2 Belongs to the R-transferase family K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000001686 205.0
HKD1_k127_504732_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000003298 192.0
HKD1_k127_504732_4 - - - - 0.00000000000000000000000000000001218 135.0
HKD1_k127_504732_5 Prokaryotic cytochrome b561 - - - 0.00000000000000000000001672 101.0
HKD1_k127_5049616_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 426.0
HKD1_k127_5049616_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 337.0
HKD1_k127_5049616_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 324.0
HKD1_k127_5049616_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000001983 186.0
HKD1_k127_5049616_4 - - - - 0.0000000000000000002264 88.0
HKD1_k127_5055051_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
HKD1_k127_5055051_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000001441 197.0
HKD1_k127_5055051_2 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000008021 151.0
HKD1_k127_5055051_3 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0004157 50.0
HKD1_k127_5064655_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000004202 183.0
HKD1_k127_5064655_1 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.000000000001177 72.0
HKD1_k127_5064780_0 Pyridine nucleotide-disulphide oxidoreductase - - - 6.296e-202 646.0
HKD1_k127_5064780_1 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 291.0
HKD1_k127_5064780_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008622 281.0
HKD1_k127_5064780_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000003927 215.0
HKD1_k127_5070152_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1236.0
HKD1_k127_5070152_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 492.0
HKD1_k127_5070152_10 Ankyrin repeats (many copies) K06867 - - 0.00000000002772 75.0
HKD1_k127_5070152_11 FecR protein - - - 0.0001766 53.0
HKD1_k127_5070152_2 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HKD1_k127_5070152_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000001042 222.0
HKD1_k127_5070152_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000004064 140.0
HKD1_k127_5070152_5 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000004971 138.0
HKD1_k127_5070152_6 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000311 134.0
HKD1_k127_5070152_7 recombinase activity K06400 - - 0.00000000000000000000000002715 111.0
HKD1_k127_5070152_8 Thioredoxin-like - - - 0.000000000000000000000009603 110.0
HKD1_k127_5070152_9 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000001221 94.0
HKD1_k127_5081134_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 5.062e-214 670.0
HKD1_k127_5081134_1 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 584.0
HKD1_k127_5081134_2 Pfam:T6SS_VasB K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 311.0
HKD1_k127_5081134_3 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000001806 161.0
HKD1_k127_5081134_4 TIGRFAM Type VI secretion system, lysozyme-related K11897 - - 0.0000000000000000000000000000000331 132.0
HKD1_k127_5081134_5 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000002364 70.0
HKD1_k127_5082402_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 415.0
HKD1_k127_5082402_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
HKD1_k127_5082402_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001311 279.0
HKD1_k127_5082402_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000002605 264.0
HKD1_k127_5082402_4 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000001128 205.0
HKD1_k127_5082402_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000001963 124.0
HKD1_k127_5082402_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00006856 55.0
HKD1_k127_5103295_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.978e-232 728.0
HKD1_k127_5103295_1 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 424.0
HKD1_k127_5103295_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001205 277.0
HKD1_k127_5103295_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000006484 121.0
HKD1_k127_5103295_4 VanZ like family - - - 0.000000000000000000002405 101.0
HKD1_k127_5103295_5 cAMP biosynthetic process - - - 0.0001643 45.0
HKD1_k127_5111761_0 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000001922 235.0
HKD1_k127_5111761_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
HKD1_k127_5111761_2 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000005652 157.0
HKD1_k127_5111761_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000003265 142.0
HKD1_k127_5111761_4 Chlorite dismutase - - - 0.000000000000000000000000000000002715 135.0
HKD1_k127_5111761_5 - - - - 0.00000005316 64.0
HKD1_k127_5111761_6 - - - - 0.00002681 51.0
HKD1_k127_5129512_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000001269 183.0
HKD1_k127_5129512_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000004124 173.0
HKD1_k127_5129512_3 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000009243 131.0
HKD1_k127_5142992_0 alpha-L-rhamnosidase - - - 3.717e-246 785.0
HKD1_k127_5142992_1 Beta-eliminating lyase K01668 - 4.1.99.2 1.122e-231 724.0
HKD1_k127_5142992_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 587.0
HKD1_k127_5142992_3 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 580.0
HKD1_k127_5142992_4 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 568.0
HKD1_k127_5142992_5 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000002647 209.0
HKD1_k127_5148841_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 591.0
HKD1_k127_5148841_1 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 466.0
HKD1_k127_5148841_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007368 274.0
HKD1_k127_5148841_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000002164 118.0
HKD1_k127_5148841_4 Belongs to the UPF0234 family K09767 - - 0.000000000000008248 75.0
HKD1_k127_5159064_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004072 284.0
HKD1_k127_5159064_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000001723 228.0
HKD1_k127_5159064_2 Caspase domain - - - 0.00000000142 71.0
HKD1_k127_5175020_0 - - - - 0.00000000000000000000000000000000006654 150.0
HKD1_k127_5175020_1 Stage II sporulation protein - - - 0.0000000000000000000002781 108.0
HKD1_k127_5175020_2 domain protein K01637,K20276 - 4.1.3.1 0.0000000000002986 79.0
HKD1_k127_5182432_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 5.285e-198 630.0
HKD1_k127_5182432_1 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 576.0
HKD1_k127_5182432_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 467.0
HKD1_k127_5182432_3 PFAM HypF finger K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 431.0
HKD1_k127_5182432_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001993 257.0
HKD1_k127_5182432_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000002129 110.0
HKD1_k127_5182523_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 2.242e-300 936.0
HKD1_k127_5182523_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 474.0
HKD1_k127_5182523_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000001062 64.0
HKD1_k127_5182523_11 Pfam:N_methyl_2 - - - 0.00000007341 54.0
HKD1_k127_5182523_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 449.0
HKD1_k127_5182523_3 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
HKD1_k127_5182523_4 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009637 266.0
HKD1_k127_5182523_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000009775 256.0
HKD1_k127_5182523_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000001297 243.0
HKD1_k127_5182523_7 D,D-heptose 1,7-bisphosphate phosphatase K03273,K15669 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.71,3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000003996 181.0
HKD1_k127_5182523_8 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000001981 150.0
HKD1_k127_5182523_9 GDP-mannose 4,6 dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000007425 112.0
HKD1_k127_5194957_0 protein conserved in bacteria - - - 1.541e-201 643.0
HKD1_k127_5194957_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 1.715e-198 633.0
HKD1_k127_5194957_2 Myo-inositol-1-phosphate synthase GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 473.0
HKD1_k127_5194957_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 433.0
HKD1_k127_5194957_4 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 428.0
HKD1_k127_5194957_5 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
HKD1_k127_5194957_6 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000528 183.0
HKD1_k127_5194957_7 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000002746 96.0
HKD1_k127_5194957_8 Domain of unknown function (DUF202) K00389 - - 0.000000000000002353 81.0
HKD1_k127_520665_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000004791 265.0
HKD1_k127_520665_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000001048 229.0
HKD1_k127_520665_2 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000292 115.0
HKD1_k127_5207941_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 546.0
HKD1_k127_5207941_1 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006408 298.0
HKD1_k127_5222403_0 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
HKD1_k127_5234277_0 lipopolysaccharide transport K22110 - - 0.0 1352.0
HKD1_k127_5234277_1 choline dehydrogenase activity - - - 1.826e-250 781.0
HKD1_k127_5234277_10 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000009344 184.0
HKD1_k127_5234277_11 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000001578 147.0
HKD1_k127_5234277_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 604.0
HKD1_k127_5234277_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 507.0
HKD1_k127_5234277_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 396.0
HKD1_k127_5234277_5 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HKD1_k127_5234277_6 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
HKD1_k127_5234277_7 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000006312 211.0
HKD1_k127_5234277_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001567 188.0
HKD1_k127_5234277_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000007298 186.0
HKD1_k127_5243327_0 transporter - - - 7.997e-233 746.0
HKD1_k127_5243327_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000003924 98.0
HKD1_k127_5243327_2 lysyltransferase activity K01531,K07027,K20468 - 3.6.3.2 0.00000006283 61.0
HKD1_k127_5254731_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 539.0
HKD1_k127_5254731_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 451.0
HKD1_k127_5254731_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 334.0
HKD1_k127_5254731_3 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000000000002414 142.0
HKD1_k127_5254731_4 Transposase IS200 like K07491 - - 0.0000000000000000000001078 102.0
HKD1_k127_5254731_5 peptidyl-tyrosine sulfation - - - 0.0002248 52.0
HKD1_k127_5263748_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.097e-301 945.0
HKD1_k127_5263748_1 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 451.0
HKD1_k127_5263748_2 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 308.0
HKD1_k127_5263748_3 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000003592 203.0
HKD1_k127_5263748_4 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000001475 189.0
HKD1_k127_5263748_5 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000002966 99.0
HKD1_k127_5263748_6 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000000000004844 79.0
HKD1_k127_5263748_7 polygalacturonase activity K13925 - - 0.000000002575 70.0
HKD1_k127_5270151_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 322.0
HKD1_k127_5270151_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000003062 198.0
HKD1_k127_5270151_2 Hep Hag repeat protein - - - 0.00000000000000001061 98.0
HKD1_k127_5274207_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 422.0
HKD1_k127_5274207_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005132 288.0
HKD1_k127_5274207_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000002041 78.0
HKD1_k127_5274207_3 - - - - 0.00001275 47.0
HKD1_k127_5288921_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 608.0
HKD1_k127_5288921_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 382.0
HKD1_k127_5288921_2 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000001405 201.0
HKD1_k127_5288921_3 Pfam:N_methyl_2 - - - 0.0001846 49.0
HKD1_k127_5290559_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1094.0
HKD1_k127_5290559_1 Protein of unknown function (DUF3142) - - - 0.000000002014 70.0
HKD1_k127_5290559_2 - - - - 0.000000002744 71.0
HKD1_k127_5320253_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.552e-234 738.0
HKD1_k127_5320253_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 524.0
HKD1_k127_5320253_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000001565 108.0
HKD1_k127_5320253_4 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.000000000005925 70.0
HKD1_k127_533342_0 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
HKD1_k127_533342_1 Pilus assembly protein PilX K02673 - - 0.000000000001622 81.0
HKD1_k127_533342_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000009131 57.0
HKD1_k127_5335731_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 580.0
HKD1_k127_5335731_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 412.0
HKD1_k127_5335731_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
HKD1_k127_5335731_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000005803 181.0
HKD1_k127_5335731_4 membrane protein (DUF2127) - - - 0.00000000000000003173 86.0
HKD1_k127_5339935_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
HKD1_k127_5339935_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001248 203.0
HKD1_k127_5339935_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000004037 159.0
HKD1_k127_5339935_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000002753 139.0
HKD1_k127_5339935_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000001503 112.0
HKD1_k127_5339935_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000007387 94.0
HKD1_k127_5339935_6 Psort location Cytoplasmic, score 8.87 K06960 - - 0.000000000000000001782 88.0
HKD1_k127_5339935_7 - - - - 0.00002399 50.0
HKD1_k127_5341997_0 A-macroglobulin receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 367.0
HKD1_k127_5343778_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 334.0
HKD1_k127_5343778_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000256 274.0
HKD1_k127_5343778_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000003412 183.0
HKD1_k127_5359271_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.218e-257 812.0
HKD1_k127_5359271_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 600.0
HKD1_k127_5359271_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000003313 175.0
HKD1_k127_5359271_11 Biotin-requiring enzyme K02160 - - 0.00000000000000000000000000000000000003308 149.0
HKD1_k127_5359271_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000001328 124.0
HKD1_k127_5359271_13 rRNA binding K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001363 126.0
HKD1_k127_5359271_14 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000228 123.0
HKD1_k127_5359271_15 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000003432 89.0
HKD1_k127_5359271_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004425 74.0
HKD1_k127_5359271_17 Ribosomal protein L30 K02907 - - 0.000000000000005759 76.0
HKD1_k127_5359271_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 467.0
HKD1_k127_5359271_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 432.0
HKD1_k127_5359271_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 298.0
HKD1_k127_5359271_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
HKD1_k127_5359271_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000002656 215.0
HKD1_k127_5359271_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000008451 211.0
HKD1_k127_5359271_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000001833 179.0
HKD1_k127_5359271_9 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000002687 178.0
HKD1_k127_5366738_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 1.646e-200 631.0
HKD1_k127_5366738_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000005161 175.0
HKD1_k127_5366738_2 Belongs to the 'phage' integrase family - - - 0.000000000003279 70.0
HKD1_k127_5367831_0 amino acid - - - 1.607e-238 754.0
HKD1_k127_5367831_1 PFAM Peptidase S10, serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 536.0
HKD1_k127_5367831_2 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 374.0
HKD1_k127_5367831_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002279 272.0
HKD1_k127_5367831_4 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000001236 158.0
HKD1_k127_5367831_5 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000001931 160.0
HKD1_k127_5367831_6 Probable zinc-ribbon domain - - - 0.0000000000000000000000003117 109.0
HKD1_k127_5367831_7 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000008113 77.0
HKD1_k127_5367831_8 protein import - - - 0.000000001693 70.0
HKD1_k127_5367831_9 PFAM Polysaccharide export protein K01991 - - 0.0000005351 61.0
HKD1_k127_5370552_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000002781 200.0
HKD1_k127_5370552_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000001641 56.0
HKD1_k127_5370552_2 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000952 47.0
HKD1_k127_5381854_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 343.0
HKD1_k127_5381854_1 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001965 280.0
HKD1_k127_5400084_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 398.0
HKD1_k127_5400084_1 chaperone-mediated protein folding K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 316.0
HKD1_k127_5404485_0 class II (D K K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 595.0
HKD1_k127_5404485_1 protein secretion by the type I secretion system K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 354.0
HKD1_k127_5404485_2 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001901 242.0
HKD1_k127_540933_0 cellulose binding - - - 2.298e-308 964.0
HKD1_k127_540933_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.062e-224 715.0
HKD1_k127_540933_10 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000002019 73.0
HKD1_k127_540933_11 Tetratricopeptide repeat - - - 0.00002617 55.0
HKD1_k127_540933_2 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 478.0
HKD1_k127_540933_3 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
HKD1_k127_540933_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000624 188.0
HKD1_k127_540933_5 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000002301 174.0
HKD1_k127_540933_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000001323 104.0
HKD1_k127_540933_7 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000004121 107.0
HKD1_k127_540933_8 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000002569 85.0
HKD1_k127_540933_9 TIGRFAM TonB family K03832 - - 0.00000000000001901 83.0
HKD1_k127_5416457_0 - - - - 0.00000000000000000000000000000000000000000000006222 175.0
HKD1_k127_5416457_1 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000001251 136.0
HKD1_k127_5416457_2 Putative zinc ribbon domain - - - 0.0000000000000000009883 88.0
HKD1_k127_5452476_0 Rhamnogalacturonate lyase K18195 GO:0005575,GO:0005576 4.2.2.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 593.0
HKD1_k127_5452476_1 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 554.0
HKD1_k127_5452476_2 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 475.0
HKD1_k127_5452476_3 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 248.0
HKD1_k127_5463220_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 337.0
HKD1_k127_5463220_1 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.00000000000000000000000000000000000000000000000000004247 192.0
HKD1_k127_5463220_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000002665 73.0
HKD1_k127_5463220_3 PFAM Fimbrial assembly family protein K02663 - - 0.0000001295 61.0
HKD1_k127_5463220_4 general secretion pathway protein - - - 0.0007475 51.0
HKD1_k127_5466408_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 396.0
HKD1_k127_5466408_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 338.0
HKD1_k127_5466408_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000019 244.0
HKD1_k127_5466408_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000001537 192.0
HKD1_k127_5466408_4 R3H domain protein K06346 - - 0.00000000000000000138 91.0
HKD1_k127_5466408_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000003912 66.0
HKD1_k127_5510984_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 465.0
HKD1_k127_5510984_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 379.0
HKD1_k127_5510984_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000004918 232.0
HKD1_k127_5510984_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000003041 199.0
HKD1_k127_5510984_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000369 184.0
HKD1_k127_5510984_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000005244 155.0
HKD1_k127_5512462_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003317 238.0
HKD1_k127_5521639_0 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
HKD1_k127_5521639_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000384 96.0
HKD1_k127_5521639_2 Multicopper oxidase K22350 - 1.16.3.3 0.0000008209 63.0
HKD1_k127_5546418_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 579.0
HKD1_k127_5546418_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 306.0
HKD1_k127_5546418_2 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000003852 204.0
HKD1_k127_5546418_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000001922 89.0
HKD1_k127_5546418_4 dnaJ homolog subfamily C member 30-like K19374 - - 0.0000000000000119 84.0
HKD1_k127_5546418_5 Biopolymer transport protein K03559 - - 0.0000000000008347 74.0
HKD1_k127_5556620_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004588 274.0
HKD1_k127_5556620_1 serine-type peptidase activity K06889 - - 0.00000000000000000000007202 98.0
HKD1_k127_5580724_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
HKD1_k127_5580724_1 Transglutaminase-like - - - 0.0000004184 62.0
HKD1_k127_5604853_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 388.0
HKD1_k127_5604853_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 338.0
HKD1_k127_5604853_2 Forkhead associated domain K01990,K21397 - - 0.000005687 57.0
HKD1_k127_561864_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 439.0
HKD1_k127_561864_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 357.0
HKD1_k127_561864_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 332.0
HKD1_k127_561864_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 323.0
HKD1_k127_561864_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 319.0
HKD1_k127_561864_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001127 295.0
HKD1_k127_561864_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001214 230.0
HKD1_k127_561864_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000002929 58.0
HKD1_k127_5619269_0 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 448.0
HKD1_k127_5619269_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000002729 163.0
HKD1_k127_5619269_2 RDD family - - - 0.0000000000000000000000000000000000000003149 160.0
HKD1_k127_5619269_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000001588 120.0
HKD1_k127_5619269_4 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000003859 80.0
HKD1_k127_5619269_5 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0000006437 54.0
HKD1_k127_5619458_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 296.0
HKD1_k127_5619458_1 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001388 254.0
HKD1_k127_5619458_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
HKD1_k127_5619458_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000002615 207.0
HKD1_k127_5619458_4 Pfam RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000002044 211.0
HKD1_k127_5619458_5 glyoxalase III activity K02005 - - 0.0000000000000000000000000000000000000000000000009624 181.0
HKD1_k127_5619458_6 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000001905 175.0
HKD1_k127_5619458_7 domain, Protein K21449 - - 0.000000000000000000000000000000004545 147.0
HKD1_k127_5641854_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 592.0
HKD1_k127_5641854_1 nadh flavin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 460.0
HKD1_k127_5641854_2 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000005873 187.0
HKD1_k127_5641854_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000008436 186.0
HKD1_k127_5655636_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 474.0
HKD1_k127_5655636_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000005705 114.0
HKD1_k127_5672668_0 peptidase K07386 - - 2.236e-257 810.0
HKD1_k127_5672668_1 Protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000000000000000002987 179.0
HKD1_k127_5672668_2 SMART Chromosomal replication initiator DnaA domain - - - 0.000000000002877 68.0
HKD1_k127_5672668_3 Restriction endonuclease-like protein K07454 - - 0.0003889 48.0
HKD1_k127_5745750_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 496.0
HKD1_k127_5745750_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000003717 219.0
HKD1_k127_5745750_2 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000001212 193.0
HKD1_k127_5745750_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000002247 126.0
HKD1_k127_5794940_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 291.0
HKD1_k127_5794940_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000001027 202.0
HKD1_k127_5794940_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000004259 78.0
HKD1_k127_5794940_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000191 50.0
HKD1_k127_5832166_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 457.0
HKD1_k127_5832166_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000003617 63.0
HKD1_k127_5836789_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 473.0
HKD1_k127_5836789_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
HKD1_k127_5836789_2 Protein of unknown function DUF72 - - - 0.000000000000000000001137 96.0
HKD1_k127_5879260_0 CO dehydrogenase flavoprotein C-terminal domain K03519,K11178 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 440.0
HKD1_k127_5879260_1 2Fe-2S iron-sulfur cluster binding domain K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 315.0
HKD1_k127_5879260_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
HKD1_k127_5879260_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000499 272.0
HKD1_k127_5879260_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000005062 190.0
HKD1_k127_5879260_5 peptidase activity - - - 0.00000000000000000000000000000000000000000000001988 190.0
HKD1_k127_5879260_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.0000000000000000000000000000000000009586 142.0
HKD1_k127_5879260_7 - - - - 0.000000000000000007009 98.0
HKD1_k127_5879260_9 (FHA) domain - - - 0.000001853 61.0
HKD1_k127_5885143_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 439.0
HKD1_k127_5885143_1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000002585 114.0
HKD1_k127_5885143_2 - - - - 0.00000000000003526 79.0
HKD1_k127_5885143_3 Serine threonine protein kinase K08884 - 2.7.11.1 0.0003798 44.0
HKD1_k127_6040138_0 cellulose binding - - - 0.0 1208.0
HKD1_k127_6040138_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 567.0
HKD1_k127_6040138_2 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 464.0
HKD1_k127_6040138_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 385.0
HKD1_k127_6040138_4 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 308.0
HKD1_k127_6040138_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000001123 159.0
HKD1_k127_6040138_6 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000001497 151.0
HKD1_k127_6040138_7 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.000000000000000000000000002753 117.0
HKD1_k127_6040138_8 Domain of Unknown Function (DUF350) - - - 0.000000000000000004418 86.0
HKD1_k127_604441_0 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 363.0
HKD1_k127_604441_1 ABC transporter K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 351.0
HKD1_k127_604441_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
HKD1_k127_604441_3 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
HKD1_k127_604441_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000003269 233.0
HKD1_k127_604441_5 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000003704 166.0
HKD1_k127_604441_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000007217 156.0
HKD1_k127_604441_7 Phosphate-selective porin O and P - - - 0.0000000000002 83.0
HKD1_k127_6055186_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1350.0
HKD1_k127_6055186_1 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1239.0
HKD1_k127_6055186_10 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 336.0
HKD1_k127_6055186_11 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
HKD1_k127_6055186_12 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004706 287.0
HKD1_k127_6055186_13 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
HKD1_k127_6055186_15 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000009148 142.0
HKD1_k127_6055186_16 - - - - 0.0000000000042 76.0
HKD1_k127_6055186_17 electron transfer activity K03737,K05337 - 1.2.7.1 0.0001029 55.0
HKD1_k127_6055186_2 serine dehydratase beta chain K01752 - 4.3.1.17 1.048e-243 763.0
HKD1_k127_6055186_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 582.0
HKD1_k127_6055186_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 541.0
HKD1_k127_6055186_5 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 469.0
HKD1_k127_6055186_6 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 423.0
HKD1_k127_6055186_7 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
HKD1_k127_6055186_8 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 397.0
HKD1_k127_6055186_9 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HKD1_k127_6078438_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.601e-253 793.0
HKD1_k127_6078438_1 CAAX protease self-immunity - - - 0.000000000000000000000000000002826 128.0
HKD1_k127_6084850_0 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 439.0
HKD1_k127_6084850_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
HKD1_k127_6084850_10 transmembrane transporter activity - - - 0.0000000000000000000005117 106.0
HKD1_k127_6084850_11 LytTr DNA-binding domain - - - 0.00000000000000000001221 102.0
HKD1_k127_6084850_12 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000002414 75.0
HKD1_k127_6084850_13 Domain of unknown function (DUF4136) - - - 0.000005221 56.0
HKD1_k127_6084850_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
HKD1_k127_6084850_3 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000007315 196.0
HKD1_k127_6084850_4 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000452 196.0
HKD1_k127_6084850_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000005859 186.0
HKD1_k127_6084850_6 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000008138 176.0
HKD1_k127_6084850_7 Transposase IS200 like - - - 0.00000000000000000000000000000000000000004179 156.0
HKD1_k127_6084850_8 Putative lumazine-binding - - - 0.0000000000000000000000000000000000001131 147.0
HKD1_k127_6084850_9 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000006647 131.0
HKD1_k127_608556_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 312.0
HKD1_k127_608556_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 292.0
HKD1_k127_608556_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 293.0
HKD1_k127_608556_3 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 302.0
HKD1_k127_608556_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000001652 209.0
HKD1_k127_608556_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000004411 211.0
HKD1_k127_608556_6 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000002117 153.0
HKD1_k127_608556_7 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000003044 132.0
HKD1_k127_6092485_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 558.0
HKD1_k127_6092485_1 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 529.0
HKD1_k127_6092485_2 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 395.0
HKD1_k127_6092485_3 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 387.0
HKD1_k127_6092485_4 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006837 218.0
HKD1_k127_6092485_5 Stage II sporulation protein M - - - 0.000000000000000000000000003587 115.0
HKD1_k127_6106839_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 629.0
HKD1_k127_6106839_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 422.0
HKD1_k127_6106839_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000004475 216.0
HKD1_k127_6112127_0 Glycosyl hydrolases family 15 - - - 6.791e-204 653.0
HKD1_k127_6112127_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 423.0
HKD1_k127_6112127_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 396.0
HKD1_k127_6112127_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
HKD1_k127_6112127_4 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009531 266.0
HKD1_k127_6112127_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000002744 219.0
HKD1_k127_6112127_6 Belongs to the Nudix hydrolase family - - - 0.00000000000000008377 83.0
HKD1_k127_6112127_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000004062 66.0
HKD1_k127_6115643_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008909 259.0
HKD1_k127_6115643_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000004451 181.0
HKD1_k127_6115643_2 UPF0314 protein - - - 0.000000000000000000000000000000000000000000000001134 181.0
HKD1_k127_6115643_3 RmlD substrate binding domain K01711 - 4.2.1.47 0.00000000000000467 74.0
HKD1_k127_6115643_4 - - - - 0.00000000008782 72.0
HKD1_k127_6115643_5 ABC transporter related K01990 - - 0.000000003682 67.0
HKD1_k127_6115643_6 Domain of unknown function (DUF4149) - - - 0.0001691 51.0
HKD1_k127_6134759_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 424.0
HKD1_k127_6134759_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000007938 186.0
HKD1_k127_6134759_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000001263 122.0
HKD1_k127_6134759_3 - - - - 0.0000000000000004296 88.0
HKD1_k127_6134759_4 PspA/IM30 family K03969 - - 0.00006771 53.0
HKD1_k127_6148256_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 246.0
HKD1_k127_6148256_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000721 141.0
HKD1_k127_6148256_2 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000007425 138.0
HKD1_k127_6148256_3 Redoxin K03564 - 1.11.1.15 0.000000000000000003855 83.0
HKD1_k127_6148256_4 Rhodanese Homology Domain - - - 0.0000139 52.0
HKD1_k127_6155410_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 409.0
HKD1_k127_6155410_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000003179 158.0
HKD1_k127_6155410_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000001702 129.0
HKD1_k127_6181257_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 466.0
HKD1_k127_6181257_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 331.0
HKD1_k127_6181257_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000647 288.0
HKD1_k127_6181257_3 peptidyl-tyrosine sulfation - - - 0.000000023 65.0
HKD1_k127_6181294_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
HKD1_k127_6181294_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
HKD1_k127_6181294_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000009651 158.0
HKD1_k127_6181294_3 Sigma-70, region 4 K03088 - - 0.000000003487 59.0
HKD1_k127_6181294_4 PFAM Uncharacterised protein domain Spy-rel - - - 0.0001472 51.0
HKD1_k127_6207595_0 Tricorn protease PDZ domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 353.0
HKD1_k127_6207595_1 CHY zinc finger - - - 0.00000000000000000000000000000000000000000001813 166.0
HKD1_k127_6207595_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000001281 164.0
HKD1_k127_6207595_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000007095 132.0
HKD1_k127_6207595_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000002831 110.0
HKD1_k127_6207595_5 Tetratricopeptide repeat - - - 0.00000000001648 78.0
HKD1_k127_6214443_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 475.0
HKD1_k127_6214443_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 356.0
HKD1_k127_6220873_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 319.0
HKD1_k127_6220873_1 DoxX K16937 - 1.8.5.2 0.0000000000000000000001359 98.0
HKD1_k127_6220873_2 - - - - 0.00002518 55.0
HKD1_k127_6220873_3 - - - - 0.00008185 48.0
HKD1_k127_6261340_0 Sodium:sulfate symporter transmembrane region K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 434.0
HKD1_k127_6261340_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0007687 49.0
HKD1_k127_6279380_0 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 395.0
HKD1_k127_6279380_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
HKD1_k127_6279380_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000004451 137.0
HKD1_k127_6279380_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000008892 109.0
HKD1_k127_6279380_4 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000005144 93.0
HKD1_k127_6279380_5 COG3209 Rhs family protein - - - 0.000000000002804 77.0
HKD1_k127_6285395_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 404.0
HKD1_k127_6285395_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000003255 229.0
HKD1_k127_6285395_2 Lecithin:cholesterol acyltransferase - - - 0.0000000000000000000000000000000000000001717 167.0
HKD1_k127_6285395_3 30S ribosomal protein Thx K19033 - - 0.0001073 46.0
HKD1_k127_630714_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 413.0
HKD1_k127_630714_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 288.0
HKD1_k127_630714_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000001392 225.0
HKD1_k127_630714_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000002916 168.0
HKD1_k127_630714_4 penicillin-binding protein - - - 0.000000000000000000000000000000000000000001096 176.0
HKD1_k127_630714_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000003002 156.0
HKD1_k127_630714_6 S23 ribosomal protein - - - 0.000000000000000000000000000007551 122.0
HKD1_k127_6339224_0 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000001409 179.0
HKD1_k127_6339224_1 Amino-transferase class IV - - - 0.000000000000000000000000000008787 126.0
HKD1_k127_6339224_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.00004881 55.0
HKD1_k127_6347152_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 379.0
HKD1_k127_6347152_1 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 350.0
HKD1_k127_6347152_2 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 341.0
HKD1_k127_6347152_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003209 291.0
HKD1_k127_6347152_4 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000004752 172.0
HKD1_k127_6347152_5 Polymorphic membrane protein, Chlamydia - - - 0.00000000000000000000000000118 132.0
HKD1_k127_6363390_0 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000001017 202.0
HKD1_k127_6364435_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 405.0
HKD1_k127_6364435_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 379.0
HKD1_k127_6364435_2 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000003958 127.0
HKD1_k127_6364435_3 Lanthionine synthetase C family protein - - - 0.000001062 61.0
HKD1_k127_6364435_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00002301 49.0
HKD1_k127_6368153_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 332.0
HKD1_k127_6368153_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 304.0
HKD1_k127_6368153_2 Cell division protein FtsQ K03589 - - 0.0000000001476 71.0
HKD1_k127_6429047_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.786e-227 717.0
HKD1_k127_6429047_1 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 284.0
HKD1_k127_6429047_2 PFAM AhpC TSA family - - - 0.0000000000000000000000000000000000000000000000001362 183.0
HKD1_k127_6429047_3 6-phosphogluconolactonase activity - - - 0.0000002051 59.0
HKD1_k127_6430165_0 type VI secretion protein, VC_A0114 family K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008165 283.0
HKD1_k127_6430165_1 metal cluster binding - - - 0.000000000000000000000000000000000000000000000000004324 191.0
HKD1_k127_6430165_2 histone H2A K63-linked ubiquitination - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000007692 74.0
HKD1_k127_6430165_3 Lytic transglycosylase catalytic K08307 - - 0.0001777 46.0
HKD1_k127_6434425_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
HKD1_k127_6434425_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000001411 159.0
HKD1_k127_6434425_2 Transcriptional - - - 0.0000000000000000000000000000000000001854 145.0
HKD1_k127_6434425_3 PFAM Cysteine-rich secretory protein family - - - 0.000000000000000000000000000544 119.0
HKD1_k127_6445933_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.508e-210 679.0
HKD1_k127_6445933_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 516.0
HKD1_k127_6445933_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 438.0
HKD1_k127_6445933_3 Putative metallopeptidase - - - 0.000000000000000000000000000000000000000000002326 176.0
HKD1_k127_6445933_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000001876 166.0
HKD1_k127_6445933_5 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000006566 138.0
HKD1_k127_6445933_6 - - - - 0.0009509 49.0
HKD1_k127_6458554_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 323.0
HKD1_k127_6458554_1 DNA repair exonuclease K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005809 264.0
HKD1_k127_6458554_2 ATP-dependent protease La (LON) domain K01338 - 3.4.21.53 0.0000000000000000000004713 100.0
HKD1_k127_6458554_3 nucleic acid phosphodiester bond hydrolysis K07576,K07577 - - 0.000000001281 59.0
HKD1_k127_6460375_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 481.0
HKD1_k127_6460375_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 468.0
HKD1_k127_6460375_2 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 449.0
HKD1_k127_6460375_3 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 366.0
HKD1_k127_6460375_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
HKD1_k127_6460375_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
HKD1_k127_6460375_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 274.0
HKD1_k127_6460375_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000006805 264.0
HKD1_k127_6460375_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000000000000000000001787 207.0
HKD1_k127_6460375_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000002298 200.0
HKD1_k127_6461024_0 - - - - 0.000000000000000000000000000000000000000000000005701 175.0
HKD1_k127_6461024_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000005726 170.0
HKD1_k127_6461024_2 - - - - 0.000000000000000000000000000000000000002051 153.0
HKD1_k127_6461024_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000003894 111.0
HKD1_k127_6461024_4 Methyltransferase domain - - - 0.00000000000000000000000001873 110.0
HKD1_k127_6461024_5 signal transduction histidine kinase - - - 0.0000000000000000002562 102.0
HKD1_k127_6461024_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0005265 51.0
HKD1_k127_6496929_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 379.0
HKD1_k127_6496929_1 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000692 216.0
HKD1_k127_6496929_2 surface antigen variable number - - - 0.00000000000000000000000000000000001143 154.0
HKD1_k127_6496929_3 - K05826 - - 0.00001196 50.0
HKD1_k127_6496939_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 556.0
HKD1_k127_6496939_1 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 398.0
HKD1_k127_6496939_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 348.0
HKD1_k127_6501526_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 503.0
HKD1_k127_6501526_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000005214 180.0
HKD1_k127_6501526_2 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000002647 166.0
HKD1_k127_6501526_3 polyketide cyclase - - - 0.0000000000000000000004512 98.0
HKD1_k127_6505241_0 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000003135 148.0
HKD1_k127_6505241_1 transcriptional regulator K07662 - - 0.0000000000000000000000000000000000002007 142.0
HKD1_k127_6505241_2 Heavy-metal resistance - - - 0.0000000000000113 80.0
HKD1_k127_6525772_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 485.0
HKD1_k127_6525772_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 402.0
HKD1_k127_6525772_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002598 269.0
HKD1_k127_6525772_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000006314 106.0
HKD1_k127_6525772_4 - - - - 0.000000000000003554 86.0
HKD1_k127_6528515_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 489.0
HKD1_k127_6528515_1 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 481.0
HKD1_k127_6528515_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 362.0
HKD1_k127_6528515_3 Glycosyl transferases group 1 - - - 0.0000000000000000001821 89.0
HKD1_k127_6541150_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.662e-197 624.0
HKD1_k127_6541150_1 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 370.0
HKD1_k127_6541150_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000324 103.0
HKD1_k127_6541150_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000008544 102.0
HKD1_k127_6553174_0 Tricorn protease homolog - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 597.0
HKD1_k127_6553174_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 260.0
HKD1_k127_6553174_2 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000199 235.0
HKD1_k127_6553174_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000567 211.0
HKD1_k127_6553174_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000003774 164.0
HKD1_k127_6553174_5 AI-2E family transporter - - - 0.0000000000000000000000000000001973 138.0
HKD1_k127_6564082_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 347.0
HKD1_k127_6564082_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000161 197.0
HKD1_k127_6564082_2 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000002186 178.0
HKD1_k127_6567272_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.204e-267 833.0
HKD1_k127_6567272_1 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 1.92e-222 697.0
HKD1_k127_6567272_2 DNA polymerase IV (family X) K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 522.0
HKD1_k127_6567272_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 411.0
HKD1_k127_6567272_4 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000001287 206.0
HKD1_k127_6567272_5 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.0000000000000000000000000000000000000000000000000949 186.0
HKD1_k127_6567272_6 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000001928 177.0
HKD1_k127_6567272_7 PFAM Cold-shock protein, DNA-binding - - - 0.0000000000000000000000000003016 118.0
HKD1_k127_6567272_8 Universal stress protein family - - - 0.000000000000000000001548 100.0
HKD1_k127_6567272_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000001141 75.0
HKD1_k127_6570775_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 407.0
HKD1_k127_6570775_1 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 351.0
HKD1_k127_6570775_2 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000001336 158.0
HKD1_k127_6570775_3 Protein of unknown function (DUF433) - - - 0.000000000000000002453 87.0
HKD1_k127_6570775_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000008783 79.0
HKD1_k127_6570775_5 - - - - 0.00000000005621 65.0
HKD1_k127_660541_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 3.379e-274 862.0
HKD1_k127_660541_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
HKD1_k127_660541_2 nitrite transmembrane transporter activity - - - 0.000000000000000000001912 97.0
HKD1_k127_6623378_0 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 323.0
HKD1_k127_6623378_1 Arginase family K01479 - 3.5.3.8 0.000000000000000001608 97.0
HKD1_k127_6635222_0 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000001805 117.0
HKD1_k127_6635222_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000003243 53.0
HKD1_k127_6667519_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 352.0
HKD1_k127_6667519_1 Tetratricopeptide repeats K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 346.0
HKD1_k127_6667519_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002808 288.0
HKD1_k127_6667519_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001347 186.0
HKD1_k127_6667519_4 Tetratricopeptide repeats - - - 0.000000000000004932 78.0
HKD1_k127_6679962_0 Glycogen debranching enzyme - - - 1.225e-208 664.0
HKD1_k127_6679962_1 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003904 283.0
HKD1_k127_6679962_2 DoxX - - - 0.00000000000000000000000000000000000000000004469 164.0
HKD1_k127_6679962_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000181 166.0
HKD1_k127_6744026_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 572.0
HKD1_k127_6744026_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 486.0
HKD1_k127_6744026_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 357.0
HKD1_k127_6744026_3 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140,K22187 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 292.0
HKD1_k127_6758639_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 541.0
HKD1_k127_6758639_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 372.0
HKD1_k127_6758639_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000004579 136.0
HKD1_k127_6758639_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000007286 84.0
HKD1_k127_6758639_5 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000606 52.0
HKD1_k127_6768372_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.351e-201 636.0
HKD1_k127_6768372_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 544.0
HKD1_k127_6768372_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
HKD1_k127_6768372_3 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.0000000000000000000000000000000001089 142.0
HKD1_k127_6768372_4 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000005721 83.0
HKD1_k127_6768372_5 - - - - 0.0000000001631 65.0
HKD1_k127_6768372_6 Permease, YjgP YjgQ family K11720 - - 0.00000002779 67.0
HKD1_k127_6827896_0 Thiosulfate reductase cytochrome B subunit (Membrane anchoring - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 263.0
HKD1_k127_6827896_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002111 253.0
HKD1_k127_6827896_2 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000003795 182.0
HKD1_k127_6827896_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000009536 158.0
HKD1_k127_6827896_4 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000005341 153.0
HKD1_k127_6827896_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000003606 141.0
HKD1_k127_6827896_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000001075 94.0
HKD1_k127_6832058_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003625 276.0
HKD1_k127_6832058_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.00000000000000000000000000000002623 134.0
HKD1_k127_6832058_2 Tetratricopeptide repeat K20543 - - 0.000002754 60.0
HKD1_k127_6859463_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.856e-195 617.0
HKD1_k127_6859463_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 413.0
HKD1_k127_6859463_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000001986 164.0
HKD1_k127_6859463_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000005702 135.0
HKD1_k127_6859463_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000003502 109.0
HKD1_k127_6859463_5 PFAM ABC transporter related K06020 - 3.6.3.25 0.00000000000003324 72.0
HKD1_k127_6872339_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 2.605e-247 775.0
HKD1_k127_6872339_1 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 533.0
HKD1_k127_6872339_2 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 376.0
HKD1_k127_6872339_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000001586 190.0
HKD1_k127_6872339_4 Peptidase family M23 - - - 0.000000000000000000000324 103.0
HKD1_k127_6872339_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000005699 102.0
HKD1_k127_6872339_6 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000001219 101.0
HKD1_k127_6872339_7 - - - - 0.0000000007441 72.0
HKD1_k127_688699_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 559.0
HKD1_k127_688699_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 512.0
HKD1_k127_688699_2 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000007384 190.0
HKD1_k127_688699_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.00000000000000000000000004898 111.0
HKD1_k127_688699_4 Rhodanese Homology Domain - - - 0.0000000000008244 69.0
HKD1_k127_6943388_0 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 370.0
HKD1_k127_6943388_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000008761 177.0
HKD1_k127_6943388_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000001548 118.0
HKD1_k127_6973646_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 566.0
HKD1_k127_6973646_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 299.0
HKD1_k127_6973646_10 N-terminal region of micro-spherule protein K11674 GO:0000123,GO:0000228,GO:0000785,GO:0000790,GO:0002151,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005783,GO:0005844,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010521,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0012505,GO:0016043,GO:0016569,GO:0016570,GO:0016573,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0030234,GO:0030425,GO:0031011,GO:0031248,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033202,GO:0034046,GO:0034708,GO:0035097,GO:0036211,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043086,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043543,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044463,GO:0044464,GO:0044665,GO:0045934,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051338,GO:0051348,GO:0051972,GO:0051974,GO:0060255,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070603,GO:0070717,GO:0071339,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097346,GO:0097447,GO:0097458,GO:0098772,GO:0120025,GO:0120038,GO:1900180,GO:1900182,GO:1901363,GO:1901564,GO:1902493,GO:1902494,GO:1903827,GO:1903829,GO:1904356,GO:1904357,GO:1904749,GO:1904751,GO:1904949,GO:1990234,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251 - 0.0001027 53.0
HKD1_k127_6973646_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 274.0
HKD1_k127_6973646_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000001736 119.0
HKD1_k127_6973646_4 response regulator - - - 0.000000000000000000002045 100.0
HKD1_k127_6973646_5 Iron dependent repressor, N-terminal DNA binding domain - - - 0.000000000000000000008142 98.0
HKD1_k127_6973646_6 - - - - 0.00000000000000001185 87.0
HKD1_k127_6973646_7 Universal stress protein family - - - 0.00000000000000008128 86.0
HKD1_k127_6973646_8 PA14 domain - - - 0.0000000000000003792 91.0
HKD1_k127_6973646_9 Protein of unknown function (DUF402) K07586 - - 0.0000000000002 76.0
HKD1_k127_7043133_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1393.0
HKD1_k127_7043133_1 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 5.244e-320 1002.0
HKD1_k127_7043133_2 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 432.0
HKD1_k127_7043133_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 368.0
HKD1_k127_7043133_4 Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000002517 239.0
HKD1_k127_7043133_5 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000514 135.0
HKD1_k127_7043133_6 protein N-acetylglucosaminyltransferase activity K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00000000000001842 87.0
HKD1_k127_7043133_7 Leucine-rich repeat (LRR) protein - - - 0.00001443 53.0
HKD1_k127_7043133_8 Homodimerisation domain of SGTA K16365 GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006620,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0015031,GO:0015833,GO:0016192,GO:0032947,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0090150 - 0.000706 49.0
HKD1_k127_7049250_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 578.0
HKD1_k127_7049250_1 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000001567 163.0
HKD1_k127_7049250_3 Protease with the C-terminal PDZ domain - - - 0.0003964 53.0
HKD1_k127_7049451_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 500.0
HKD1_k127_7049451_1 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004338 238.0
HKD1_k127_7049451_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000001653 136.0
HKD1_k127_7049451_3 Tetratricopeptide repeat - - - 0.0000000000003194 74.0
HKD1_k127_7056572_0 TonB dependent receptor K16090 - - 1.887e-208 674.0
HKD1_k127_7056572_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.125e-206 661.0
HKD1_k127_7056572_2 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 375.0
HKD1_k127_7056572_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000004002 229.0
HKD1_k127_7056572_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000002297 207.0
HKD1_k127_7056572_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000002896 168.0
HKD1_k127_7056572_6 PFAM HD domain - - - 0.000000000000000000000000000000006291 136.0
HKD1_k127_7056572_7 Chaperone protein DNAj K03686 GO:0000003,GO:0000740,GO:0000741,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006457,GO:0006458,GO:0006996,GO:0006997,GO:0007275,GO:0007349,GO:0008150,GO:0008219,GO:0009553,GO:0009558,GO:0009559,GO:0009561,GO:0009653,GO:0009856,GO:0009987,GO:0010197,GO:0010198,GO:0010623,GO:0012501,GO:0016043,GO:0022414,GO:0030154,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0048229,GO:0048284,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051084,GO:0051085,GO:0051704,GO:0061024,GO:0061025,GO:0061077,GO:0071840,GO:0090174 - 0.000002938 60.0
HKD1_k127_7056572_8 peptidyl-tyrosine sulfation - - - 0.00002064 57.0
HKD1_k127_7056572_9 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.0003142 52.0
HKD1_k127_7058823_0 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 434.0
HKD1_k127_7058823_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005507 250.0
HKD1_k127_7058823_2 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000000000006548 203.0
HKD1_k127_7058823_3 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.0000000000000000000000000000000000003868 155.0
HKD1_k127_7058823_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000008322 52.0
HKD1_k127_7058823_5 Copper binding periplasmic protein CusF - - - 0.0003502 49.0
HKD1_k127_7065917_0 PFAM aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 510.0
HKD1_k127_7065917_1 UDP-glucose 4-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
HKD1_k127_7065917_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 295.0
HKD1_k127_7065917_3 - - - - 0.0000000000000000000000000000000000000000000319 166.0
HKD1_k127_7065917_4 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000002589 111.0
HKD1_k127_7077560_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 569.0
HKD1_k127_7077560_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 299.0
HKD1_k127_7077560_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000009827 266.0
HKD1_k127_7077560_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000857 177.0
HKD1_k127_7092631_0 COG3209 Rhs family protein - - - 0.000000000002921 77.0
HKD1_k127_7094691_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 365.0
HKD1_k127_7094691_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000001124 247.0
HKD1_k127_7094691_2 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000000000001732 180.0
HKD1_k127_7094691_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000003544 115.0
HKD1_k127_7098545_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
HKD1_k127_7098545_1 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008695 206.0
HKD1_k127_7098545_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000009957 124.0
HKD1_k127_7098545_3 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000002302 60.0
HKD1_k127_7099454_0 Tricorn protease C1 domain K08676 - - 3.229e-202 647.0
HKD1_k127_7099454_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000003939 169.0
HKD1_k127_7109560_0 - - - - 0.00000000000001003 84.0
HKD1_k127_7109560_1 SdpI/YhfL protein family - - - 0.000000001302 63.0
HKD1_k127_7110073_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 358.0
HKD1_k127_7110073_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000001064 241.0
HKD1_k127_7110073_2 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000003725 107.0
HKD1_k127_7110073_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00000005813 64.0
HKD1_k127_7110301_0 silver ion transport K15726 - - 2.264e-269 861.0
HKD1_k127_7110301_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 419.0
HKD1_k127_7110301_2 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001784 248.0
HKD1_k127_7110301_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001212 246.0
HKD1_k127_7110301_4 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000001219 204.0
HKD1_k127_7110301_5 PFAM Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000262 181.0
HKD1_k127_7110301_6 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000005796 86.0
HKD1_k127_7110301_7 - - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00001053 55.0
HKD1_k127_7120294_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.714e-203 643.0
HKD1_k127_7120294_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 393.0
HKD1_k127_7120294_10 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000002347 138.0
HKD1_k127_7120294_11 Membrane K00368 - 1.7.2.1 0.00000000000000000000000000001374 122.0
HKD1_k127_7120294_12 Cupredoxin-like domain - - - 0.000000000000000000000001125 108.0
HKD1_k127_7120294_13 NIPSNAP family containing protein - - - 0.000000000000000000000005542 105.0
HKD1_k127_7120294_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000004715 59.0
HKD1_k127_7120294_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000002722 53.0
HKD1_k127_7120294_2 Belongs to the N(4) N(6)-methyltransferase family K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 385.0
HKD1_k127_7120294_3 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 357.0
HKD1_k127_7120294_4 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
HKD1_k127_7120294_5 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 289.0
HKD1_k127_7120294_6 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000004726 224.0
HKD1_k127_7120294_7 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000011 202.0
HKD1_k127_7120294_8 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000998 165.0
HKD1_k127_7120294_9 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000002621 160.0
HKD1_k127_7120876_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 441.0
HKD1_k127_7120876_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004677 275.0
HKD1_k127_7122972_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 421.0
HKD1_k127_7122972_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
HKD1_k127_7122972_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000007038 189.0
HKD1_k127_7122972_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000009171 145.0
HKD1_k127_7122972_4 Ribosomal protein L35 K02916 - - 0.0000000000000000008298 87.0
HKD1_k127_7127238_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 489.0
HKD1_k127_7127238_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 442.0
HKD1_k127_7137702_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 554.0
HKD1_k127_7137702_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 459.0
HKD1_k127_7137702_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 394.0
HKD1_k127_7137702_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 311.0
HKD1_k127_7137702_4 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000001189 183.0
HKD1_k127_7137702_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000007539 168.0
HKD1_k127_7137702_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000006917 156.0
HKD1_k127_7137702_7 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.00000000000000000000000000000000000001416 155.0
HKD1_k127_7156079_0 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 332.0
HKD1_k127_7156079_1 DNA/RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
HKD1_k127_7166216_0 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001271 293.0
HKD1_k127_7166216_1 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000002417 193.0
HKD1_k127_7166216_2 peptidase K01415,K07386 - 3.4.24.71 0.00000000000000000000000007145 111.0
HKD1_k127_7166216_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0002695 52.0
HKD1_k127_7166216_4 Tetratricopeptide repeat - - - 0.0005702 51.0
HKD1_k127_7180013_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.241e-227 718.0
HKD1_k127_7180013_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 416.0
HKD1_k127_7180013_2 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 278.0
HKD1_k127_7180013_3 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000002892 186.0
HKD1_k127_7180013_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000001198 75.0
HKD1_k127_7197012_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 380.0
HKD1_k127_7197012_1 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
HKD1_k127_7197012_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
HKD1_k127_7197012_3 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000004043 152.0
HKD1_k127_7197012_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000002292 137.0
HKD1_k127_7197012_5 EthD domain - - - 0.00000000000000000000000000000002568 129.0
HKD1_k127_7197012_6 - - - - 0.000000000000000000000000000001453 131.0
HKD1_k127_7197012_7 - - - - 0.000000000000000000000000002314 116.0
HKD1_k127_7197012_8 Nuclease A inhibitor-like protein - - - 0.0000000000000002466 84.0
HKD1_k127_7197012_9 - - - - 0.00000000000002747 78.0
HKD1_k127_7205400_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 507.0
HKD1_k127_7205400_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 302.0
HKD1_k127_7205400_10 PFAM Pilus assembly protein PilO K02664 - - 0.0000000005077 68.0
HKD1_k127_7205400_2 Polyprenyl synthetase K13789 GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000009931 242.0
HKD1_k127_7205400_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000001657 254.0
HKD1_k127_7205400_4 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000004664 229.0
HKD1_k127_7205400_5 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K16048 - - 0.0000000000000000000000000000000000000000000000672 173.0
HKD1_k127_7205400_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001758 173.0
HKD1_k127_7205400_7 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000893 145.0
HKD1_k127_7205400_8 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000005225 102.0
HKD1_k127_7205400_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000306 75.0
HKD1_k127_7210040_0 Alpha/beta hydrolase family - - - 9.426e-241 758.0
HKD1_k127_7210040_1 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 338.0
HKD1_k127_7210040_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 330.0
HKD1_k127_7210040_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000004934 142.0
HKD1_k127_7210040_4 PIN domain - - - 0.0000000000000000000000002627 111.0
HKD1_k127_7210040_5 Transglycosylase SLT domain K08309 - - 0.000000000000000000000006 108.0
HKD1_k127_7210040_6 aspartic-type endopeptidase activity - - - 0.0001154 55.0
HKD1_k127_7210040_7 Cell division cycle K03350 GO:0000003,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0000375,GO:0000377,GO:0000398,GO:0001775,GO:0003002,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005680,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0007049,GO:0007088,GO:0007091,GO:0007275,GO:0007338,GO:0007343,GO:0007346,GO:0007389,GO:0008150,GO:0008152,GO:0008283,GO:0008356,GO:0008380,GO:0009056,GO:0009057,GO:0009566,GO:0009798,GO:0009948,GO:0009949,GO:0009952,GO:0009987,GO:0010467,GO:0010498,GO:0010564,GO:0010965,GO:0015630,GO:0016070,GO:0016071,GO:0016192,GO:0016567,GO:0016740,GO:0017156,GO:0019538,GO:0019787,GO:0019899,GO:0019902,GO:0019903,GO:0019941,GO:0019953,GO:0022402,GO:0022414,GO:0030163,GO:0031145,GO:0031461,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044784,GO:0045055,GO:0046483,GO:0046903,GO:0048519,GO:0048856,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0051603,GO:0051704,GO:0051726,GO:0051783,GO:0051983,GO:0060467,GO:0060468,GO:0060471,GO:0061630,GO:0061659,GO:0065001,GO:0065007,GO:0070013,GO:0070647,GO:0070979,GO:0071704,GO:0080154,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903047,GO:1905818,GO:1990234,GO:2000241,GO:2000242 - 0.0002013 54.0
HKD1_k127_7213019_0 diphthine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 535.0
HKD1_k127_7213019_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 353.0
HKD1_k127_7213019_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 298.0
HKD1_k127_7213019_3 HD domain - - - 0.00000000000000000000000000000000000000000000000002362 195.0
HKD1_k127_7213019_4 cytochrome - - - 0.0000000000000000000000000000000000001472 149.0
HKD1_k127_7213019_5 MerR, DNA binding - - - 0.000000000000000000000000000000002066 135.0
HKD1_k127_7213019_6 - - - - 0.0000000000000000000000000008806 121.0
HKD1_k127_7213019_7 - - - - 0.000000000000000000000000006017 124.0
HKD1_k127_7213019_8 Glycosyl hydrolase family 1 - - - 0.000000000000000007208 85.0
HKD1_k127_7213019_9 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000001894 53.0
HKD1_k127_7230446_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 576.0
HKD1_k127_7230446_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 531.0
HKD1_k127_7230446_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002481 282.0
HKD1_k127_7230446_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000002328 164.0
HKD1_k127_7230446_4 Methyltransferase K08316 - 2.1.1.171 0.000001851 55.0
HKD1_k127_7231173_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 364.0
HKD1_k127_7231173_1 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000048 78.0
HKD1_k127_7231173_2 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000006631 68.0
HKD1_k127_7242488_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 394.0
HKD1_k127_7242488_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000003898 192.0
HKD1_k127_7242488_2 SpoIVB peptidase S55 - - - 0.00002911 49.0
HKD1_k127_7248777_0 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008262 284.0
HKD1_k127_7248777_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000005069 228.0
HKD1_k127_7248777_2 - - - - 0.00000000006374 66.0
HKD1_k127_7252088_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.642e-198 638.0
HKD1_k127_7252088_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 585.0
HKD1_k127_7252088_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 357.0
HKD1_k127_7252088_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 349.0
HKD1_k127_7252088_4 - - - - 0.00000000000000000002075 100.0
HKD1_k127_7266494_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 329.0
HKD1_k127_7266494_1 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 269.0
HKD1_k127_7266494_2 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000001116 237.0
HKD1_k127_7266494_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000002993 104.0
HKD1_k127_7266494_4 peptidase - - - 0.00000002047 56.0
HKD1_k127_7266494_5 Plasmid stabilization system - - - 0.000001435 54.0
HKD1_k127_7280493_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.647e-313 976.0
HKD1_k127_7280493_1 PFAM RecF RecN SMC N terminal domain K03546 - - 0.0000000000000000000000000000000000000000000000001163 201.0
HKD1_k127_7280493_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000008126 177.0
HKD1_k127_7280493_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.0000000000000000000000000000001763 127.0
HKD1_k127_7280493_4 Sigma-70 region 2 K03088 - - 0.000000000000000003076 92.0
HKD1_k127_7280493_5 - - - - 0.000000000000002951 79.0
HKD1_k127_7280493_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000103 69.0
HKD1_k127_7280493_7 Putative adhesin - - - 0.000001524 60.0
HKD1_k127_7291775_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 439.0
HKD1_k127_7291775_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000007035 143.0
HKD1_k127_7291775_2 Transposase IS200 like - - - 0.000000000000000000006871 98.0
HKD1_k127_7291775_3 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000009905 84.0
HKD1_k127_7291775_4 Protein of unknown function (DUF4019) - - - 0.0000000000002 76.0
HKD1_k127_7300238_0 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 341.0
HKD1_k127_7300238_1 Calcineurin-like phosphoesterase - - - 0.000000000000000002809 87.0
HKD1_k127_7344595_0 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000008242 222.0
HKD1_k127_7344595_1 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000006697 186.0
HKD1_k127_7344595_2 nuclear chromosome segregation - - - 0.0000000000005757 82.0
HKD1_k127_7344595_3 Domain of unknown function (DUF4440) - - - 0.000001456 57.0
HKD1_k127_7345812_0 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 448.0
HKD1_k127_7345812_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000006708 176.0
HKD1_k127_7345812_2 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000002407 57.0
HKD1_k127_7390439_0 - - - - 0.000000000000000000000000000000000000000005144 163.0
HKD1_k127_7390439_1 spermidine synthase K00797 - 2.5.1.16 0.00000000001237 72.0
HKD1_k127_7396802_0 virulence factor MVIN family protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 428.0
HKD1_k127_7396802_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000002182 220.0
HKD1_k127_7396802_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
HKD1_k127_739687_0 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 503.0
HKD1_k127_739687_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 414.0
HKD1_k127_739687_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007909 278.0
HKD1_k127_739687_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000006451 248.0
HKD1_k127_739687_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000332 202.0
HKD1_k127_739687_5 lytic transglycosylase activity K03194 - - 0.00000000000008249 84.0
HKD1_k127_739687_6 triphosphatase activity - - - 0.0000000002976 68.0
HKD1_k127_7400806_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004607 261.0
HKD1_k127_7400806_1 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000004987 207.0
HKD1_k127_7404270_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1096.0
HKD1_k127_7404270_1 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 560.0
HKD1_k127_7404270_2 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000116 233.0
HKD1_k127_7404270_3 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.000000000000000000000007816 101.0
HKD1_k127_7444715_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 349.0
HKD1_k127_7444715_1 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000001852 180.0
HKD1_k127_7460539_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 344.0
HKD1_k127_7460539_1 PFAM Sulfite exporter TauE SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000001687 240.0
HKD1_k127_7460539_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000003546 75.0
HKD1_k127_7460539_3 Domain of unknown function (DUF4350) - - - 0.000000000002405 79.0
HKD1_k127_7460539_4 pathogenesis - - - 0.00000008033 64.0
HKD1_k127_7460539_5 Domain of unknown function (DUF4129) - - - 0.00000325 59.0
HKD1_k127_7468249_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 546.0
HKD1_k127_7468249_1 COG0467 RecA-superfamily ATPases implicated in signal K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 539.0
HKD1_k127_7468249_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 362.0
HKD1_k127_7468249_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500,K11755 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 332.0
HKD1_k127_7468249_4 Belongs to the PRA-CH family K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003506 256.0
HKD1_k127_7468249_5 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000001577 217.0
HKD1_k127_7468249_6 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000001309 179.0
HKD1_k127_7468582_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 283.0
HKD1_k127_7468582_1 (GNAT) family K22441 - 2.3.1.57 0.0000000000000000000000000000000000008676 146.0
HKD1_k127_7468582_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000003183 105.0
HKD1_k127_7468582_3 chaperone-mediated protein folding - - - 0.000000005438 59.0
HKD1_k127_748589_0 Amidohydrolase family K06015 - 3.5.1.81 1.519e-223 705.0
HKD1_k127_7487393_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000054 184.0
HKD1_k127_7487393_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000005864 154.0
HKD1_k127_7487393_2 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000006284 122.0
HKD1_k127_7504589_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 408.0
HKD1_k127_7504589_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 294.0
HKD1_k127_7504589_2 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000001428 114.0
HKD1_k127_7504589_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000007525 115.0
HKD1_k127_7504761_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 505.0
HKD1_k127_7504761_1 7TM-HD extracellular K07037 - - 0.000000000002884 79.0
HKD1_k127_7508738_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.467e-269 835.0
HKD1_k127_7508738_1 EamA-like transporter family - - - 0.0000000000000000002179 93.0
HKD1_k127_7533528_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000005215 257.0
HKD1_k127_7533528_1 - - - - 0.0000000179 59.0
HKD1_k127_7533528_2 Protein of unknown function (DUF3108) - - - 0.000471 53.0
HKD1_k127_75340_0 DNA RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HKD1_k127_75340_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000009147 224.0
HKD1_k127_75340_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000007774 203.0
HKD1_k127_75340_3 - - - - 0.000000000000000000000000000000000000000000000000000258 190.0
HKD1_k127_75340_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000002004 182.0
HKD1_k127_75340_5 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000002452 111.0
HKD1_k127_75340_6 Copper binding periplasmic protein CusF - - - 0.00006981 52.0
HKD1_k127_7553516_0 Pregnancy-associated plasma protein-A - - - 0.0 1094.0
HKD1_k127_7553516_1 amine dehydrogenase activity - - - 4.264e-250 791.0
HKD1_k127_7553516_10 - - - - 0.000001079 62.0
HKD1_k127_7553516_11 Bacterial SH3 domain homologues - - - 0.00003683 53.0
HKD1_k127_7553516_2 PFAM Na-Ca exchanger integrin-beta4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 400.0
HKD1_k127_7553516_3 Domain of unknown function (DUF4280) - - - 0.000000000000000000000000000000000000000000000000007431 183.0
HKD1_k127_7553516_4 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000006442 150.0
HKD1_k127_7553516_5 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000001842 139.0
HKD1_k127_7553516_6 - - - - 0.00000000000000000003022 92.0
HKD1_k127_7553516_7 - - - - 0.0000000000000001129 95.0
HKD1_k127_7553516_8 Belongs to the peptidase S8 family - - - 0.000000004361 70.0
HKD1_k127_7556269_0 cellulose binding - - - 2.258e-208 662.0
HKD1_k127_7556269_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 434.0
HKD1_k127_7556269_10 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000003056 126.0
HKD1_k127_7556269_2 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001195 251.0
HKD1_k127_7556269_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000005143 239.0
HKD1_k127_7556269_4 Endoribonuclease L-PSP K15067 - 3.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000006154 224.0
HKD1_k127_7556269_5 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000003589 196.0
HKD1_k127_7556269_6 DoxX - - - 0.000000000000000000000000000000000000000000000000007121 185.0
HKD1_k127_7556269_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003056 178.0
HKD1_k127_7556269_8 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000001005 171.0
HKD1_k127_7556269_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000007518 169.0
HKD1_k127_7561859_0 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 368.0
HKD1_k127_7561859_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000002238 255.0
HKD1_k127_7585968_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000002368 185.0
HKD1_k127_7585968_1 mRNA binding - - - 0.00000000000000000000000003161 109.0
HKD1_k127_7585968_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000004144 102.0
HKD1_k127_7585968_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000007793 97.0
HKD1_k127_7585968_4 GyrI-like small molecule binding domain - - - 0.000000000005311 74.0
HKD1_k127_7585968_5 domain, Protein - - - 0.0000000002041 70.0
HKD1_k127_7585968_6 lactoylglutathione lyase activity - - - 0.0000000002919 64.0
HKD1_k127_7585968_7 Putative zinc-finger - - - 0.00001554 55.0
HKD1_k127_7585968_8 Putative adhesin - - - 0.00006901 54.0
HKD1_k127_7592857_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 245.0
HKD1_k127_7592857_1 FAD dependent oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000002981 145.0
HKD1_k127_7592857_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000003628 121.0
HKD1_k127_7592857_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000009322 104.0
HKD1_k127_7592857_4 - - - - 0.0000000761 63.0
HKD1_k127_7592857_5 - - - - 0.00001509 56.0
HKD1_k127_7605251_0 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 576.0
HKD1_k127_7605251_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 380.0
HKD1_k127_7605251_2 Pectic acid lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 340.0
HKD1_k127_7607454_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140,K22187 - 1.2.1.18,1.2.1.27 1.305e-234 734.0
HKD1_k127_7607454_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 301.0
HKD1_k127_7607454_2 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000004278 183.0
HKD1_k127_7607454_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000002468 163.0
HKD1_k127_7646602_0 PFAM Type II secretion system protein E K02652 - - 2.608e-211 670.0
HKD1_k127_7646602_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HKD1_k127_7646602_2 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000005128 243.0
HKD1_k127_7646602_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000004156 201.0
HKD1_k127_7646602_4 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000001286 155.0
HKD1_k127_7646602_5 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000002793 141.0
HKD1_k127_7646602_6 Protein of unknown function, DUF417 - - - 0.000000000000000000000000000000003724 134.0
HKD1_k127_7646602_7 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.000000000000000000000000000001501 123.0
HKD1_k127_7646602_8 von Willebrand factor, type A - - - 0.000000000000003012 85.0
HKD1_k127_7667531_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 1.438e-256 807.0
HKD1_k127_7667531_1 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 398.0
HKD1_k127_7667531_2 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 318.0
HKD1_k127_7683418_0 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 387.0
HKD1_k127_7683418_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000001927 155.0
HKD1_k127_7683418_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000006939 76.0
HKD1_k127_7683418_3 SMART Tetratricopeptide - - - 0.000006058 51.0
HKD1_k127_7683418_4 Domain of unknown function (DUF4349) - - - 0.0001952 52.0
HKD1_k127_7685206_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 485.0
HKD1_k127_7685206_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 331.0
HKD1_k127_7710612_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.126e-198 632.0
HKD1_k127_7710612_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
HKD1_k127_7710612_2 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 321.0
HKD1_k127_7710612_3 PFAM Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000175 250.0
HKD1_k127_7710612_4 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000005579 198.0
HKD1_k127_7710612_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000343 162.0
HKD1_k127_7710612_6 Haem-binding domain - - - 0.0000000000000000000000000000007671 126.0
HKD1_k127_7710612_7 Cysteine-rich secretory protein family - - - 0.0000000000000000000007678 101.0
HKD1_k127_7713374_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 365.0
HKD1_k127_7713374_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000391 158.0
HKD1_k127_7713374_2 - - - - 0.0000000000000000000000000000000001156 145.0
HKD1_k127_7752540_0 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
HKD1_k127_7752540_1 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000001457 179.0
HKD1_k127_7752540_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000117 168.0
HKD1_k127_7752540_3 von Willebrand factor, type A - - - 0.000000000000000009454 95.0
HKD1_k127_7752540_4 Carboxypeptidase regulatory-like domain - - - 0.00000009954 62.0
HKD1_k127_7783814_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 308.0
HKD1_k127_7783814_1 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000201 179.0
HKD1_k127_7783814_2 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000001513 131.0
HKD1_k127_7783814_3 cytochrome oxidase assembly K02259 - - 0.000000000000000000417 91.0
HKD1_k127_7786712_0 oxidoreductase activity K12511 - - 0.0000000000000000000000000594 121.0
HKD1_k127_7786712_1 Domain of unknown function (DUF305) - - - 0.00000000000007489 79.0
HKD1_k127_7786712_2 - - - - 0.00000000835 61.0
HKD1_k127_7808259_0 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 347.0
HKD1_k127_7808259_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 265.0
HKD1_k127_7808259_2 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000001695 155.0
HKD1_k127_7808259_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000002536 78.0
HKD1_k127_7821822_0 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 355.0
HKD1_k127_7821822_1 YCII-related domain - - - 0.0000000000000000000000000000000000000000289 161.0
HKD1_k127_7821822_2 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000339 143.0
HKD1_k127_7821822_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000007778 113.0
HKD1_k127_7822591_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 283.0
HKD1_k127_7876508_0 Hydrolase - - - 1.224e-257 806.0
HKD1_k127_7876508_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000009761 219.0
HKD1_k127_7876508_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001718 181.0
HKD1_k127_792948_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 455.0
HKD1_k127_792948_1 Cupredoxin-like domain K00376 - 1.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 383.0
HKD1_k127_792948_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000008603 186.0
HKD1_k127_7951183_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000003349 198.0
HKD1_k127_7951183_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000006955 193.0
HKD1_k127_7951183_2 DinB family - - - 0.00000000000000000000000000000000000000000000003767 173.0
HKD1_k127_7951183_3 Multidrug transporter MatE K03327 - - 0.00000000000000000000000000000000000000001728 156.0
HKD1_k127_79991_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 572.0
HKD1_k127_79991_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 356.0
HKD1_k127_79991_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004334 258.0
HKD1_k127_79991_3 - - - - 0.0000000000000000000000000000000001878 137.0
HKD1_k127_79991_4 response regulator - - - 0.0000000000001108 72.0
HKD1_k127_800917_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 563.0
HKD1_k127_800917_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000001509 59.0
HKD1_k127_8021593_0 Belongs to the aldehyde dehydrogenase family K00128,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 422.0
HKD1_k127_8021593_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000009325 172.0
HKD1_k127_847970_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 490.0
HKD1_k127_847970_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000005956 238.0
HKD1_k127_847970_2 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000005373 232.0
HKD1_k127_847970_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000001977 158.0
HKD1_k127_847970_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000007185 127.0
HKD1_k127_847970_5 ThiS family K03154 - - 0.000000000001784 69.0
HKD1_k127_847970_6 - - - - 0.00000000009686 72.0
HKD1_k127_847970_7 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0005623 44.0
HKD1_k127_85960_0 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000509 152.0
HKD1_k127_86453_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 612.0
HKD1_k127_86453_1 peptidase - - - 0.00000000000000000000000000000000000000000005422 182.0
HKD1_k127_86453_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000001799 138.0
HKD1_k127_880208_0 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000362 269.0
HKD1_k127_880208_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000005911 154.0
HKD1_k127_897679_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000008032 171.0
HKD1_k127_897679_1 - - - - 0.00000000000000000000000000000000003511 148.0
HKD1_k127_897679_2 Glycosyltransferase like family 2 - - - 0.000000000000000000002303 96.0
HKD1_k127_900255_0 FAD-NAD(P)-binding K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 590.0
HKD1_k127_900255_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 454.0
HKD1_k127_900255_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
HKD1_k127_900255_3 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000003517 158.0
HKD1_k127_900255_4 cheY-homologous receiver domain - - - 0.0000000000000000000007406 100.0
HKD1_k127_900255_5 - - - - 0.0000000000000000007642 90.0
HKD1_k127_900255_6 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase K07777 - 2.7.13.3 0.0000000003295 63.0
HKD1_k127_900255_7 Histidine kinase - - - 0.0000000479 60.0
HKD1_k127_906442_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 329.0
HKD1_k127_927766_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 434.0
HKD1_k127_927766_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002406 279.0
HKD1_k127_927766_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000001334 97.0
HKD1_k127_927766_11 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000001176 87.0
HKD1_k127_927766_13 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000182 72.0
HKD1_k127_927766_14 competence protein - - - 0.000000000533 66.0
HKD1_k127_927766_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000002959 62.0
HKD1_k127_927766_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000007496 193.0
HKD1_k127_927766_3 - - - - 0.00000000000000000000000000000000000000000000006011 174.0
HKD1_k127_927766_4 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000006879 150.0
HKD1_k127_927766_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000003678 139.0
HKD1_k127_927766_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002686 131.0
HKD1_k127_927766_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000001864 125.0
HKD1_k127_927766_8 anaphase-promoting complex binding K02033 - - 0.000000000000000000000000005548 125.0
HKD1_k127_927766_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000001782 113.0
HKD1_k127_952935_0 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 1.025e-216 685.0
HKD1_k127_952935_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 295.0
HKD1_k127_952935_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003536 276.0
HKD1_k127_952935_3 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.00000003029 60.0
HKD1_k127_952935_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000119 49.0
HKD1_k127_95443_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 556.0
HKD1_k127_95443_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 410.0
HKD1_k127_95443_10 Thioredoxin - - - 0.00000004537 62.0
HKD1_k127_95443_11 Belongs to the UPF0232 family - - - 0.0003772 49.0
HKD1_k127_95443_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
HKD1_k127_95443_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 296.0
HKD1_k127_95443_4 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 299.0
HKD1_k127_95443_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 290.0
HKD1_k127_95443_6 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000003154 185.0
HKD1_k127_95443_7 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.000000000000000000000000000000000000003299 162.0
HKD1_k127_95443_8 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000792 139.0
HKD1_k127_95443_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000011 82.0
HKD1_k127_990182_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 340.0
HKD1_k127_990182_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 332.0
HKD1_k127_990182_2 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000002952 156.0
HKD1_k127_990182_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000001802 108.0