Overview

ID MAG01743
Name HKD1_bin.61
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_D
Class UBA1144
Order UBA2774
Family UBA2774
Genus 2-12-FULL-53-21
Species
Assembly information
Completeness (%) 91.28
Contamination (%) 2.42
GC content (%) 52.0
N50 (bp) 8,341
Genome size (bp) 2,610,825

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2428

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1014865_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 457.0
HKD1_k127_1014865_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 425.0
HKD1_k127_1014865_10 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000002937 139.0
HKD1_k127_1014865_11 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000006019 139.0
HKD1_k127_1014865_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000003213 132.0
HKD1_k127_1014865_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000006074 111.0
HKD1_k127_1014865_14 Gliding motility-associated protein GldC - - - 0.000000000000000000000005214 109.0
HKD1_k127_1014865_15 integral membrane protein - - - 0.00000000000000000003194 98.0
HKD1_k127_1014865_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 353.0
HKD1_k127_1014865_3 PFAM Methyltransferase K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
HKD1_k127_1014865_4 Enoyl-CoA hydratase/isomerase K01661,K07536 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000001142 254.0
HKD1_k127_1014865_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
HKD1_k127_1014865_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001809 237.0
HKD1_k127_1014865_7 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000003441 230.0
HKD1_k127_1014865_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000006892 216.0
HKD1_k127_1014865_9 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000002124 186.0
HKD1_k127_1054052_0 Belongs to the AAA ATPase family K13525 - - 3.259e-246 779.0
HKD1_k127_1054052_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
HKD1_k127_1054052_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000002193 237.0
HKD1_k127_1054052_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000168 184.0
HKD1_k127_1054052_4 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0003405 46.0
HKD1_k127_1096921_0 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 536.0
HKD1_k127_1096921_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 474.0
HKD1_k127_1096921_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 357.0
HKD1_k127_1096921_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000002851 189.0
HKD1_k127_1096921_4 - - - - 0.00000000000000002036 94.0
HKD1_k127_1096921_5 - - - - 0.00000000000000008396 91.0
HKD1_k127_1096921_6 Protein of unknown function (DUF861) - - - 0.000000000000001447 81.0
HKD1_k127_1096921_7 domain, Protein - - - 0.0000000001113 72.0
HKD1_k127_1096921_8 Polyphosphate kinase 2 (PPK2) - - - 0.00002496 49.0
HKD1_k127_1100043_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 526.0
HKD1_k127_1100043_1 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 491.0
HKD1_k127_1100043_2 (Hpt) domain - - - 0.00000000000001168 78.0
HKD1_k127_1106100_1 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 475.0
HKD1_k127_1106100_2 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 377.0
HKD1_k127_1106100_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000003293 231.0
HKD1_k127_1106100_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000009934 124.0
HKD1_k127_1106100_5 - - - - 0.0000000000000000000000008769 114.0
HKD1_k127_1106100_7 Lysylphosphatidylglycerol synthase TM region - - - 0.00000002273 56.0
HKD1_k127_1106100_8 Putative zinc-finger - - - 0.00006771 53.0
HKD1_k127_1126164_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 399.0
HKD1_k127_1126164_1 Aspartyl Asparaginyl beta-hydroxylase K00476,K12979 - 1.14.11.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
HKD1_k127_1126164_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000003191 166.0
HKD1_k127_1126164_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000001674 125.0
HKD1_k127_1126164_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000011 113.0
HKD1_k127_1137777_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 562.0
HKD1_k127_1137777_1 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 399.0
HKD1_k127_1137777_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000001266 234.0
HKD1_k127_1137777_3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000388 188.0
HKD1_k127_1139706_0 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 550.0
HKD1_k127_1139706_1 Adventurous gliding motility protein R - - - 0.000000000000000000000000000000000000000000000000000002994 204.0
HKD1_k127_1139706_2 COG0003 Oxyanion-translocating ATPase K01551 - 3.6.3.16 0.0000000000000000000000000005757 125.0
HKD1_k127_1146862_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 567.0
HKD1_k127_1146862_1 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 533.0
HKD1_k127_1146862_2 Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 441.0
HKD1_k127_1146862_3 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006105 282.0
HKD1_k127_1146862_4 pyridoxamine 5-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000003665 185.0
HKD1_k127_1146862_5 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000001228 175.0
HKD1_k127_1146862_6 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000007058 147.0
HKD1_k127_1146862_7 RDD family - - - 0.0000000000000001205 91.0
HKD1_k127_1146862_8 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000004375 58.0
HKD1_k127_1146862_9 RDD family - - - 0.0004635 51.0
HKD1_k127_1168471_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.891e-276 869.0
HKD1_k127_1168471_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 504.0
HKD1_k127_1168471_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 380.0
HKD1_k127_1168471_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
HKD1_k127_1168471_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 346.0
HKD1_k127_1168471_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000001404 181.0
HKD1_k127_1168471_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000003905 121.0
HKD1_k127_1168471_7 Essential cell division protein K03589 - - 0.000003599 55.0
HKD1_k127_1177542_0 Sodium/hydrogen exchanger family K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 406.0
HKD1_k127_1177542_1 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002486 230.0
HKD1_k127_1177542_2 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000003476 140.0
HKD1_k127_1177542_3 Sodium/hydrogen exchanger family K11105 - - 0.00000000007094 67.0
HKD1_k127_1192105_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 493.0
HKD1_k127_1192105_1 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000007435 213.0
HKD1_k127_1192105_2 Sporulation initiation inhibitor protein Soj K03496 - - 0.0000000000000000000000000000000000000000000000000000004012 203.0
HKD1_k127_1192105_3 glyoxalase III activity - - - 0.0000000000000000000000000000000001084 139.0
HKD1_k127_1192105_4 Replication initiation and membrane attachment K02086 - - 0.0002232 53.0
HKD1_k127_1201041_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 415.0
HKD1_k127_1201041_1 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001041 192.0
HKD1_k127_1201041_2 - - - - 0.000000000000001707 79.0
HKD1_k127_1201041_3 - - - - 0.0000000000002445 78.0
HKD1_k127_1215029_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 389.0
HKD1_k127_1215029_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 338.0
HKD1_k127_1215029_2 AMP-binding enzyme - - - 0.00000911 57.0
HKD1_k127_1222643_0 Molecular chaperone. Has ATPase activity K04079 - - 1.746e-236 747.0
HKD1_k127_1222643_1 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 443.0
HKD1_k127_1222643_2 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 422.0
HKD1_k127_1222643_3 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000001396 168.0
HKD1_k127_12341_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 515.0
HKD1_k127_1248473_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 437.0
HKD1_k127_1248473_1 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 329.0
HKD1_k127_1248473_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 323.0
HKD1_k127_1248473_3 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000005024 164.0
HKD1_k127_1248473_4 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000001606 171.0
HKD1_k127_1248473_5 Belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.00000000000000000000000000000000000006023 147.0
HKD1_k127_125244_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 301.0
HKD1_k127_125244_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002366 290.0
HKD1_k127_125244_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003677 272.0
HKD1_k127_125244_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
HKD1_k127_125244_4 Protein conserved in bacteria K09986 - - 0.000000000000000000007437 98.0
HKD1_k127_125244_5 outer membrane efflux protein - - - 0.00000000009961 74.0
HKD1_k127_1270615_0 - - - - 0.000000000000000000000000000000000000000000000004216 186.0
HKD1_k127_1270615_1 phospholipase Carboxylesterase - - - 0.0000000000000003008 92.0
HKD1_k127_1270615_2 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000008402 81.0
HKD1_k127_1278575_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 299.0
HKD1_k127_1278575_1 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000004067 182.0
HKD1_k127_1278575_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000003327 138.0
HKD1_k127_1278575_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000008825 143.0
HKD1_k127_1278575_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000002797 92.0
HKD1_k127_1282108_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1458.0
HKD1_k127_1282108_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 421.0
HKD1_k127_1282108_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 370.0
HKD1_k127_1282108_3 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
HKD1_k127_1282108_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 332.0
HKD1_k127_1282108_5 Domain of unknown function DUF302 - - - 0.000000000000000000000006545 106.0
HKD1_k127_1285179_0 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
HKD1_k127_1285179_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000008062 213.0
HKD1_k127_1293099_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain - - - 0.000000000000000000000000001182 117.0
HKD1_k127_1293099_1 lipolytic protein G-D-S-L family - - - 0.000001738 58.0
HKD1_k127_1295710_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 466.0
HKD1_k127_1295710_1 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
HKD1_k127_1295710_2 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000003226 194.0
HKD1_k127_1295710_3 GIY-YIG catalytic domain - - - 0.0000000000000000000000000301 108.0
HKD1_k127_1295710_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000009254 103.0
HKD1_k127_1295710_5 endonuclease containing a URI domain K07461 - - 0.0000001912 53.0
HKD1_k127_1304817_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HKD1_k127_1304817_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 342.0
HKD1_k127_1323253_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 392.0
HKD1_k127_1323253_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 383.0
HKD1_k127_1323253_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 342.0
HKD1_k127_1323253_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000001517 225.0
HKD1_k127_1323253_4 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000007829 157.0
HKD1_k127_1323253_5 Protein conserved in bacteria - - - 0.00000000000000009043 86.0
HKD1_k127_1333804_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1365.0
HKD1_k127_1333804_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 426.0
HKD1_k127_1333804_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000002063 149.0
HKD1_k127_1333804_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000008262 104.0
HKD1_k127_1337512_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 566.0
HKD1_k127_1337512_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 561.0
HKD1_k127_1337512_2 rRNA (guanine-N2-)-methyltransferase activity K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 470.0
HKD1_k127_1337512_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 GO:0003674,GO:0004857,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008428,GO:0009892,GO:0009894,GO:0009895,GO:0010605,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0032069,GO:0032074,GO:0043086,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1902369 - 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
HKD1_k127_1337512_4 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0000000000000000000000000000000000000000001204 164.0
HKD1_k127_1337512_5 B12 binding domain - - - 0.0000000001121 70.0
HKD1_k127_1337512_6 Belongs to the 'phage' integrase family - - - 0.000001828 51.0
HKD1_k127_1355941_0 thiolester hydrolase activity K06889 - - 0.000000000000001557 87.0
HKD1_k127_1355941_1 peptidase K06889 - - 0.0009086 50.0
HKD1_k127_1362585_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 381.0
HKD1_k127_1362585_1 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0060255,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000005601 206.0
HKD1_k127_1362585_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000001107 205.0
HKD1_k127_1362585_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.0000000000000000000000000000000000000000000000007833 177.0
HKD1_k127_1362585_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000003872 128.0
HKD1_k127_143319_0 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 447.0
HKD1_k127_143319_1 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 317.0
HKD1_k127_143319_2 response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005915 248.0
HKD1_k127_1437407_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000009768 128.0
HKD1_k127_1437407_1 Tetratricopeptide repeat - - - 0.00000003015 64.0
HKD1_k127_1437407_2 Putative zinc-finger - - - 0.000003349 51.0
HKD1_k127_1437407_3 Curli production assembly/transport component CsgG - - - 0.00006439 55.0
HKD1_k127_1476151_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 358.0
HKD1_k127_1476151_1 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002266 281.0
HKD1_k127_1476151_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000004521 204.0
HKD1_k127_1476151_3 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000000000000000000005819 149.0
HKD1_k127_1476151_4 Tetratricopeptide repeat - - - 0.00000000000000000004518 98.0
HKD1_k127_1494624_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 441.0
HKD1_k127_1494624_1 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 430.0
HKD1_k127_1494624_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 269.0
HKD1_k127_1494624_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000104 221.0
HKD1_k127_1494624_4 phosphorelay sensor kinase activity K07708,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001123 208.0
HKD1_k127_1494624_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000001972 192.0
HKD1_k127_1494624_6 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.000000001204 69.0
HKD1_k127_1506631_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 555.0
HKD1_k127_1506631_1 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
HKD1_k127_1514758_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 5.434e-270 839.0
HKD1_k127_1514758_1 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
HKD1_k127_1514758_2 PFAM Cache K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000002907 244.0
HKD1_k127_1514758_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000965 70.0
HKD1_k127_1516059_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000007372 201.0
HKD1_k127_1516059_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000002305 155.0
HKD1_k127_1516059_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000005856 114.0
HKD1_k127_1531495_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 313.0
HKD1_k127_1531495_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 297.0
HKD1_k127_1531495_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000001603 97.0
HKD1_k127_1531495_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000004362 93.0
HKD1_k127_1531495_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000006191 88.0
HKD1_k127_1545819_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.151e-268 836.0
HKD1_k127_1545819_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000488 154.0
HKD1_k127_1545819_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.00000000000000000000000000005028 126.0
HKD1_k127_1545819_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000002198 85.0
HKD1_k127_1552974_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 478.0
HKD1_k127_1552974_1 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 363.0
HKD1_k127_1563637_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 601.0
HKD1_k127_1563637_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 310.0
HKD1_k127_1563637_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000007301 258.0
HKD1_k127_1563637_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006054 237.0
HKD1_k127_1563637_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000009526 110.0
HKD1_k127_1563637_5 - - - - 0.000000000002031 69.0
HKD1_k127_1563637_6 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00005272 48.0
HKD1_k127_1565450_0 - - - - 0.000000000000000000000000000000000000000000000001893 179.0
HKD1_k127_1565450_1 - - - - 0.00000000000000000000000000000000005321 136.0
HKD1_k127_1573783_0 AcrB/AcrD/AcrF family - - - 0.0 1107.0
HKD1_k127_1573783_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 404.0
HKD1_k127_1573783_2 LysM domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 359.0
HKD1_k127_1573783_3 with different specificities (related to short-chain alcohol K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 306.0
HKD1_k127_1573783_4 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000005098 151.0
HKD1_k127_1594192_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 493.0
HKD1_k127_1594192_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 329.0
HKD1_k127_1594192_2 EamA-like transporter family - - - 0.000000000008519 74.0
HKD1_k127_1594833_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 467.0
HKD1_k127_1594833_1 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000005095 149.0
HKD1_k127_1594833_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000003607 112.0
HKD1_k127_1594833_3 Cytochrome C oxidase, cbb3-type, subunit III K02305 - - 0.0000000000000000000000476 102.0
HKD1_k127_1594833_4 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000003782 73.0
HKD1_k127_1613372_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 542.0
HKD1_k127_1613372_1 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 449.0
HKD1_k127_1613372_10 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000009727 251.0
HKD1_k127_1613372_11 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001187 227.0
HKD1_k127_1613372_12 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000003395 203.0
HKD1_k127_1613372_13 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000003142 176.0
HKD1_k127_1613372_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000002017 174.0
HKD1_k127_1613372_15 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000002341 188.0
HKD1_k127_1613372_16 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000003553 172.0
HKD1_k127_1613372_17 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000006162 140.0
HKD1_k127_1613372_18 Cold-Shock Protein K03704 - - 0.0000000000000000000000005766 105.0
HKD1_k127_1613372_19 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000006601 123.0
HKD1_k127_1613372_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 347.0
HKD1_k127_1613372_20 PFAM Iron-binding zinc finger CDGSH type - - - 0.000000000000000000006185 97.0
HKD1_k127_1613372_21 - - - - 0.00000000000001077 80.0
HKD1_k127_1613372_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000002563 53.0
HKD1_k127_1613372_23 EamA-like transporter family - - - 0.000009455 53.0
HKD1_k127_1613372_24 - - - - 0.000014 56.0
HKD1_k127_1613372_3 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 328.0
HKD1_k127_1613372_4 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 296.0
HKD1_k127_1613372_5 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 284.0
HKD1_k127_1613372_6 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000375 270.0
HKD1_k127_1613372_7 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002258 263.0
HKD1_k127_1613372_8 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 251.0
HKD1_k127_1613372_9 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009345 258.0
HKD1_k127_1616522_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 541.0
HKD1_k127_1616522_1 Sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 421.0
HKD1_k127_1616522_2 LmbE family - - - 0.000000000000000000000000000000000000000000000000006024 189.0
HKD1_k127_1616522_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000003391 137.0
HKD1_k127_1616522_4 Fusaric acid resistance protein-like K15547 - - 0.000008637 59.0
HKD1_k127_1653813_0 COG0714 MoxR-like ATPases K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 417.0
HKD1_k127_1653813_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004805 287.0
HKD1_k127_1653813_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000154 261.0
HKD1_k127_1653813_3 Domain of unknown function (DUF4381) - - - 0.0000000000000000000000000001964 119.0
HKD1_k127_1653813_4 PFAM von Willebrand factor type A K07114 - - 0.0000000003534 64.0
HKD1_k127_166338_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000004233 123.0
HKD1_k127_166338_1 RadC-like JAB domain K03630 - - 0.000000000000000000001221 97.0
HKD1_k127_166338_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000222 62.0
HKD1_k127_166338_3 Cation efflux family - - - 0.0003215 45.0
HKD1_k127_1663980_0 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 458.0
HKD1_k127_1663980_1 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 435.0
HKD1_k127_1663980_2 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 323.0
HKD1_k127_1663980_3 radical SAM K21312 - 1.17.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 293.0
HKD1_k127_1663980_4 PFAM DsrE DsrF-like family - - - 0.000000000000000000000000000000000000000001591 161.0
HKD1_k127_1663980_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000007767 100.0
HKD1_k127_1663980_6 Transcriptional Regulator, XRE family with Cupin sensor - - - 0.00000000000000009983 85.0
HKD1_k127_1742315_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 287.0
HKD1_k127_1742315_1 - - - - 0.00000000000000000000000000000000005296 136.0
HKD1_k127_1742315_2 - - - - 0.000000000000000000000000000000001189 136.0
HKD1_k127_1742315_3 Lecithin:cholesterol acyltransferase - - - 0.0000000000000000000000007824 119.0
HKD1_k127_1742315_4 Protein of unknown function (DUF3574) - - - 0.00000000009707 66.0
HKD1_k127_1742315_5 tetR family - - - 0.000000005175 60.0
HKD1_k127_1742315_6 Protein of unknown function (DUF3574) - - - 0.00002135 48.0
HKD1_k127_1748407_0 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HKD1_k127_1748407_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000003512 206.0
HKD1_k127_1748407_2 acyl-coa hydrolase K01073 - 3.1.2.20 0.00000000000000000000000000000199 126.0
HKD1_k127_177085_0 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 395.0
HKD1_k127_177085_1 Succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000003882 233.0
HKD1_k127_177085_2 PFAM Cytochrome c - - - 0.000000000000000000000000000003196 127.0
HKD1_k127_177085_3 lipolytic protein G-D-S-L family - - - 0.0000000000000002231 92.0
HKD1_k127_177085_4 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000007958 86.0
HKD1_k127_177085_6 - - - - 0.000000000002485 71.0
HKD1_k127_177085_7 - - - - 0.00001716 49.0
HKD1_k127_177085_8 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00004878 52.0
HKD1_k127_1792791_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.269e-285 896.0
HKD1_k127_1792791_1 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000001378 154.0
HKD1_k127_1807219_0 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 523.0
HKD1_k127_1807219_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 339.0
HKD1_k127_1807219_2 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 264.0
HKD1_k127_1807219_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002566 267.0
HKD1_k127_1807219_4 NTPase - - - 0.0000000000000000000000000000000000000000005774 163.0
HKD1_k127_1807219_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000003887 72.0
HKD1_k127_1807219_6 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.00000000004025 69.0
HKD1_k127_1824001_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 517.0
HKD1_k127_1824001_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
HKD1_k127_1824001_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000006004 132.0
HKD1_k127_1824001_11 response regulator, receiver - - - 0.000000000000000000002186 100.0
HKD1_k127_1824001_12 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000001392 87.0
HKD1_k127_1824001_13 Thaumatin family - - - 0.00000000001794 77.0
HKD1_k127_1824001_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 351.0
HKD1_k127_1824001_3 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 346.0
HKD1_k127_1824001_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
HKD1_k127_1824001_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008007 283.0
HKD1_k127_1824001_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003103 250.0
HKD1_k127_1824001_7 FES K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000008837 241.0
HKD1_k127_1824001_8 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000000000026 162.0
HKD1_k127_1824001_9 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000001505 154.0
HKD1_k127_1859682_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
HKD1_k127_1859682_1 heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007089 257.0
HKD1_k127_1859682_2 PHP domain protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000005623 192.0
HKD1_k127_1859682_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000001969 160.0
HKD1_k127_1859682_4 Domain of unknown function (DUF1844) - - - 0.0000000000000000003652 91.0
HKD1_k127_1862936_0 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD1_k127_1862936_1 GGDEF domain K02657 - - 0.0000000000000000000001459 99.0
HKD1_k127_1865937_0 PFAM Glycosyl K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 366.0
HKD1_k127_1865937_1 OsmC-like protein - - - 0.0000000000000000002434 93.0
HKD1_k127_1865937_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000001406 57.0
HKD1_k127_1865937_3 CoA-ligase K02381 - - 0.0002483 50.0
HKD1_k127_1889779_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000006903 215.0
HKD1_k127_1889779_1 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000001677 190.0
HKD1_k127_1889898_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 499.0
HKD1_k127_1889898_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 387.0
HKD1_k127_1889898_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001057 207.0
HKD1_k127_1889898_11 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000009736 191.0
HKD1_k127_1889898_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000009727 182.0
HKD1_k127_1889898_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000006559 181.0
HKD1_k127_1889898_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000003431 169.0
HKD1_k127_1889898_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000966 159.0
HKD1_k127_1889898_16 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001995 152.0
HKD1_k127_1889898_17 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000133 143.0
HKD1_k127_1889898_18 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000002204 145.0
HKD1_k127_1889898_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000001046 139.0
HKD1_k127_1889898_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 369.0
HKD1_k127_1889898_20 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000005569 128.0
HKD1_k127_1889898_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000002502 117.0
HKD1_k127_1889898_22 Luciferase-like monooxygenase - - - 0.0000000000000000000000000001013 121.0
HKD1_k127_1889898_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001154 109.0
HKD1_k127_1889898_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000004866 105.0
HKD1_k127_1889898_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000006407 107.0
HKD1_k127_1889898_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000008997 94.0
HKD1_k127_1889898_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001268 65.0
HKD1_k127_1889898_28 Ribosomal L29 protein K02904 - - 0.0000001064 58.0
HKD1_k127_1889898_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
HKD1_k127_1889898_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 293.0
HKD1_k127_1889898_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HKD1_k127_1889898_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001718 255.0
HKD1_k127_1889898_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000003053 225.0
HKD1_k127_1889898_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001064 211.0
HKD1_k127_1889898_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000008729 200.0
HKD1_k127_1903027_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 485.0
HKD1_k127_1903027_1 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000002612 171.0
HKD1_k127_1903027_2 - - - - 0.000000000001382 75.0
HKD1_k127_1903464_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 546.0
HKD1_k127_1903464_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000005839 231.0
HKD1_k127_1903464_2 protein conserved in bacteria containing thioredoxin-like domain - - - 0.000000000000000000000000000000000000001409 155.0
HKD1_k127_1944233_0 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
HKD1_k127_1944233_1 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000009487 193.0
HKD1_k127_1951288_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 395.0
HKD1_k127_1951288_1 MgsA AAA+ ATPase C terminal K07452,K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
HKD1_k127_1951288_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 255.0
HKD1_k127_1951288_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000897 251.0
HKD1_k127_1951288_4 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000003439 195.0
HKD1_k127_1951288_5 NUDIX domain - - - 0.0000000000000000000000000000000000000000000006722 172.0
HKD1_k127_1951288_6 MaoC like domain - - - 0.00000000000000000000000000001478 124.0
HKD1_k127_1951288_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000002741 126.0
HKD1_k127_1951288_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000001726 117.0
HKD1_k127_1951288_9 Cytochrome c K12263 - - 0.000000000000000001257 90.0
HKD1_k127_1953036_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.057e-224 723.0
HKD1_k127_1953036_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 454.0
HKD1_k127_1953036_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 445.0
HKD1_k127_196229_0 regulator of chromosome condensation, RCC1 - - - 0.00000000000004273 83.0
HKD1_k127_196229_1 domain, Protein - - - 0.00000009961 65.0
HKD1_k127_1978070_0 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000001097 219.0
HKD1_k127_1978070_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000005071 212.0
HKD1_k127_1978070_2 TIGRFAM Protein of - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000003928 104.0
HKD1_k127_1978070_3 ERCC4 domain K10896 - - 0.0003196 46.0
HKD1_k127_199001_0 Major facilitator superfamily K08170 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 400.0
HKD1_k127_199001_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003416 286.0
HKD1_k127_199001_2 Glycosyl hydrolase family 67 C-terminus - - - 0.000000000000000000000009092 108.0
HKD1_k127_199001_3 Transposase - - - 0.0000000000000000000000167 102.0
HKD1_k127_199001_4 Belongs to the 'phage' integrase family - - - 0.00000004765 57.0
HKD1_k127_199001_5 - - - - 0.0000004664 58.0
HKD1_k127_2014349_0 Thi4 family K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 365.0
HKD1_k127_2014349_1 - - - - 0.000000000000003747 77.0
HKD1_k127_2014349_2 - - - - 0.00000000000896 76.0
HKD1_k127_2023609_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 2.753e-235 757.0
HKD1_k127_2023609_1 diguanylate cyclase - - - 0.0000000000000006564 83.0
HKD1_k127_2051986_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.863e-260 817.0
HKD1_k127_2051986_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 625.0
HKD1_k127_2051986_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000002122 199.0
HKD1_k127_2051986_11 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000001614 192.0
HKD1_k127_2051986_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000009578 141.0
HKD1_k127_2051986_14 PspC domain - - - 0.0000000000000000000758 90.0
HKD1_k127_2051986_15 FAD binding domain - - - 0.0000000000000000001776 91.0
HKD1_k127_2051986_17 YsiA-like protein, C-terminal region K13770 - - 0.000000000000000007209 92.0
HKD1_k127_2051986_18 metal-binding protein (DUF2103) - - - 0.00000000000004773 76.0
HKD1_k127_2051986_19 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000024 81.0
HKD1_k127_2051986_2 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 545.0
HKD1_k127_2051986_20 Peptidogalycan biosysnthesis/recognition - - - 0.000000000006323 73.0
HKD1_k127_2051986_21 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000003624 63.0
HKD1_k127_2051986_22 Cytochrome P460 - - - 0.000002418 57.0
HKD1_k127_2051986_3 ABC transporter K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 426.0
HKD1_k127_2051986_4 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 320.0
HKD1_k127_2051986_5 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 306.0
HKD1_k127_2051986_6 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002881 268.0
HKD1_k127_2051986_7 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006585 263.0
HKD1_k127_2051986_8 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001115 248.0
HKD1_k127_2051986_9 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000003106 199.0
HKD1_k127_2055477_0 Cupin K01569 - 4.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
HKD1_k127_2055477_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000001641 188.0
HKD1_k127_2055477_2 - - - - 0.00000006584 62.0
HKD1_k127_2083740_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 5.907e-203 650.0
HKD1_k127_2083740_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 483.0
HKD1_k127_2083740_10 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000002489 175.0
HKD1_k127_2083740_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000167 165.0
HKD1_k127_2083740_12 CHAT domain - - - 0.0000000000000000000000000000000004221 140.0
HKD1_k127_2083740_13 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000005615 114.0
HKD1_k127_2083740_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 472.0
HKD1_k127_2083740_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 302.0
HKD1_k127_2083740_4 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
HKD1_k127_2083740_5 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 256.0
HKD1_k127_2083740_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HKD1_k127_2083740_7 PFAM luciferase-like - - - 0.0000000000000000000000000000000000000000000000000000000002854 214.0
HKD1_k127_2083740_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000002106 176.0
HKD1_k127_2083740_9 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000009828 178.0
HKD1_k127_2102462_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 429.0
HKD1_k127_2102462_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 385.0
HKD1_k127_2102462_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001971 251.0
HKD1_k127_2102462_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004392 261.0
HKD1_k127_2102462_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000001325 211.0
HKD1_k127_2102462_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000002334 81.0
HKD1_k127_2140936_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 312.0
HKD1_k127_2140936_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
HKD1_k127_2140936_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000007839 147.0
HKD1_k127_2140936_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000003046 143.0
HKD1_k127_2140936_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000006579 54.0
HKD1_k127_2140936_5 Psort location CytoplasmicMembrane, score - - - 0.0000008634 55.0
HKD1_k127_2148147_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 495.0
HKD1_k127_2148147_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 469.0
HKD1_k127_2148147_2 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 358.0
HKD1_k127_2148147_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 327.0
HKD1_k127_2148147_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD1_k127_2148147_5 PFAM Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
HKD1_k127_2148147_6 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007136 280.0
HKD1_k127_2148147_7 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000009665 207.0
HKD1_k127_2148147_8 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000001411 169.0
HKD1_k127_2148147_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000002705 154.0
HKD1_k127_215409_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 582.0
HKD1_k127_215409_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000001487 254.0
HKD1_k127_215409_2 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000007631 196.0
HKD1_k127_215409_3 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000002929 202.0
HKD1_k127_215409_4 Bacterial type II/III secretion system short domain K02453 - - 0.0000000000000000000000000000000000000003553 168.0
HKD1_k127_215409_5 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000008596 91.0
HKD1_k127_2159001_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 238.0
HKD1_k127_2159001_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000008539 124.0
HKD1_k127_2182996_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 419.0
HKD1_k127_2182996_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
HKD1_k127_2182996_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003135 271.0
HKD1_k127_2182996_3 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HKD1_k127_2190021_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 392.0
HKD1_k127_2190021_1 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
HKD1_k127_2190021_2 KR domain K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000002899 196.0
HKD1_k127_2190021_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000003992 126.0
HKD1_k127_2190021_4 Dihydroneopterin aldolase K07589 - 5.1.99.7 0.000000000000000000000000002473 114.0
HKD1_k127_2254225_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18299 - - 0.0 1264.0
HKD1_k127_2254225_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 404.0
HKD1_k127_2254225_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 289.0
HKD1_k127_2254225_3 PFAM Outer membrane efflux protein K18300 - - 0.000000000000000000000000000000001566 135.0
HKD1_k127_2254225_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000000003797 97.0
HKD1_k127_2254225_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000003121 101.0
HKD1_k127_2325151_0 Protein of unknown function (DUF1254) - - - 2.809e-199 630.0
HKD1_k127_2325151_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 593.0
HKD1_k127_2325151_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 366.0
HKD1_k127_2325151_3 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 330.0
HKD1_k127_2325151_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000001607 199.0
HKD1_k127_2325151_5 Protein of unknown function (DUF1634) - - - 0.0000000000000000000000005995 109.0
HKD1_k127_2325151_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000008728 104.0
HKD1_k127_2325151_7 MazG-like family - - - 0.0000000000000000001077 93.0
HKD1_k127_2325151_8 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000001343 90.0
HKD1_k127_2342253_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 432.0
HKD1_k127_2342253_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 287.0
HKD1_k127_2362782_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 559.0
HKD1_k127_2362782_1 of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 555.0
HKD1_k127_2362782_10 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000001107 200.0
HKD1_k127_2362782_11 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000005357 126.0
HKD1_k127_2362782_12 - - - - 0.000000000000000000278 96.0
HKD1_k127_2362782_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 367.0
HKD1_k127_2362782_3 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 341.0
HKD1_k127_2362782_4 pfam abc K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 321.0
HKD1_k127_2362782_5 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 302.0
HKD1_k127_2362782_6 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 305.0
HKD1_k127_2362782_7 COGs COG2343 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 243.0
HKD1_k127_2362782_8 Bacterial transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000004897 233.0
HKD1_k127_2362782_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000009871 214.0
HKD1_k127_2370253_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009227 282.0
HKD1_k127_2370253_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HKD1_k127_2370253_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000002918 206.0
HKD1_k127_2370253_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000003391 160.0
HKD1_k127_2370253_4 PFAM transglutaminase domain protein - - - 0.0000000000000002216 91.0
HKD1_k127_2397901_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
HKD1_k127_2397901_1 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000001547 213.0
HKD1_k127_2397901_2 S-adenosylmethionine synthetase (AdoMet synthetase) - - - 0.0000000000000000000000000000000000000000000000000000007078 198.0
HKD1_k127_2397901_3 - - - - 0.0000000000000000000004112 98.0
HKD1_k127_2397901_4 signal-transduction protein containing cAMP-binding and CBS domains K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000002194 59.0
HKD1_k127_2397901_5 PFAM CheB methylesterase K13924 - 2.1.1.80,3.1.1.61 0.00004849 48.0
HKD1_k127_2430133_0 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 531.0
HKD1_k127_2430133_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 430.0
HKD1_k127_2430133_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
HKD1_k127_2430133_3 Histidine kinase K02482,K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000853 191.0
HKD1_k127_2430133_4 YHS domain - - - 0.0000000000000000000000000000000000000002645 155.0
HKD1_k127_2430133_5 Cupin - - - 0.000000000000000000000000000000003827 132.0
HKD1_k127_2430133_6 protein with SCP PR1 domains - - - 0.00000000000000000000000000002192 123.0
HKD1_k127_2430133_7 Cupin - - - 0.00000000000000000000000005901 112.0
HKD1_k127_2430133_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000005593 74.0
HKD1_k127_2468742_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 382.0
HKD1_k127_2468742_1 response regulator, receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 325.0
HKD1_k127_2468742_2 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 333.0
HKD1_k127_2468742_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K19707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 322.0
HKD1_k127_2468742_4 Alginate export K16081 - - 0.000000000000000000000000000000000000000000000001128 191.0
HKD1_k127_2468742_5 - - - - 0.0000000000000000000000000000000000000000000009672 174.0
HKD1_k127_2468742_6 transcriptional regulator - - - 0.00000000000000000000000051 108.0
HKD1_k127_2468742_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000008372 108.0
HKD1_k127_2468742_8 hydrolase activity, acting on ester bonds - - - 0.00000000002863 68.0
HKD1_k127_2468742_9 - - - - 0.000000001274 68.0
HKD1_k127_2492243_0 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 329.0
HKD1_k127_2492243_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 312.0
HKD1_k127_2492243_2 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000002494 202.0
HKD1_k127_2492243_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000001521 102.0
HKD1_k127_2492243_4 - - - - 0.000000000001725 71.0
HKD1_k127_2492301_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 0.0 1115.0
HKD1_k127_2492301_1 PFAM methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.000000000000000009011 85.0
HKD1_k127_2506005_0 DNA polymerase A domain K02335 - 2.7.7.7 1.584e-268 853.0
HKD1_k127_2521574_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
HKD1_k127_2526204_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 554.0
HKD1_k127_2526204_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000001336 187.0
HKD1_k127_2526204_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000003376 179.0
HKD1_k127_2526204_3 Protein of unknown function (DUF3426) - - - 0.00001259 57.0
HKD1_k127_25267_0 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 614.0
HKD1_k127_25267_1 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
HKD1_k127_25267_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000003642 199.0
HKD1_k127_25267_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000002715 192.0
HKD1_k127_25267_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000002057 140.0
HKD1_k127_25267_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000123 106.0
HKD1_k127_25267_6 - - - - 0.00000000000000000000005565 107.0
HKD1_k127_25267_7 zinc-ribbon domain - - - 0.0000000000009867 76.0
HKD1_k127_25267_8 function. Source PGD - - - 0.00000009592 61.0
HKD1_k127_25267_9 nitrite reductase K00368 - 1.7.2.1 0.00006657 55.0
HKD1_k127_2537628_0 DnaJ central domain - - - 0.0000000005851 73.0
HKD1_k127_2541017_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 590.0
HKD1_k127_2541017_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 427.0
HKD1_k127_2541017_10 Protein of unknown function (DUF1318) K09978 - - 0.00000000000000002022 91.0
HKD1_k127_2541017_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 393.0
HKD1_k127_2541017_3 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 375.0
HKD1_k127_2541017_4 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001842 258.0
HKD1_k127_2541017_5 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000006535 211.0
HKD1_k127_2541017_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000003238 191.0
HKD1_k127_2541017_7 YicC domain protein - - - 0.00000000000000000000000000000000000000000000162 175.0
HKD1_k127_2541017_8 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000009716 121.0
HKD1_k127_2541017_9 Protein involved in outer membrane biogenesis K09800 - - 0.0000000000000000001246 102.0
HKD1_k127_2549567_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.937e-228 721.0
HKD1_k127_2549567_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 462.0
HKD1_k127_2549567_10 EamA-like transporter family - - - 0.00000001246 66.0
HKD1_k127_2549567_2 Sodium transporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
HKD1_k127_2549567_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000003762 222.0
HKD1_k127_2549567_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000616 203.0
HKD1_k127_2549567_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000002845 193.0
HKD1_k127_2549567_6 LysE type translocator - - - 0.000000000000000000000000000000000000001284 154.0
HKD1_k127_2549567_7 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000002015 96.0
HKD1_k127_2549567_8 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000002612 71.0
HKD1_k127_2549567_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000129 72.0
HKD1_k127_2561658_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 328.0
HKD1_k127_2561697_0 diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000000000005719 183.0
HKD1_k127_2561697_1 Calcineurin-like phosphoesterase superfamily domain K07313 - 3.1.3.16 0.000000000000000000000000000000000000001798 156.0
HKD1_k127_2561697_2 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000002018 134.0
HKD1_k127_260283_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.788e-274 854.0
HKD1_k127_260283_1 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 393.0
HKD1_k127_2620551_0 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 311.0
HKD1_k127_2620551_1 - K01992 - - 0.000000000000000000000000000000114 127.0
HKD1_k127_2620551_2 Domain of unknown function (DUF4340) - - - 0.00000006208 62.0
HKD1_k127_2623917_0 Arginyl tRNA synthetase N terminal domain K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 533.0
HKD1_k127_2623917_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
HKD1_k127_2623917_2 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.000000000000000000000000000000000000007748 153.0
HKD1_k127_2623917_3 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000003383 137.0
HKD1_k127_2623917_4 Tol-Pal system TolA K03646 - - 0.0000000335 66.0
HKD1_k127_2623917_5 peptidoglycan binding - - - 0.0005335 50.0
HKD1_k127_264744_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00033,K00616,K01810,K08300,K13810 - 1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9 0.0 1033.0
HKD1_k127_264744_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 601.0
HKD1_k127_264744_10 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000003897 231.0
HKD1_k127_264744_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000001433 205.0
HKD1_k127_264744_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000003201 208.0
HKD1_k127_264744_13 Haloacid dehalogenase-like hydrolase K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000000003398 196.0
HKD1_k127_264744_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000004813 188.0
HKD1_k127_264744_15 Alpha/beta hydrolase family - - - 0.00000000000009652 81.0
HKD1_k127_264744_16 It is involved in the biological process described with metabolic process K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009790,GO:0009792,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0032501,GO:0032502,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0048856,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000001283 72.0
HKD1_k127_264744_17 MarR family transcriptional regulator - - - 0.0000002005 59.0
HKD1_k127_264744_2 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 485.0
HKD1_k127_264744_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 473.0
HKD1_k127_264744_4 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 371.0
HKD1_k127_264744_5 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 318.0
HKD1_k127_264744_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
HKD1_k127_264744_7 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 308.0
HKD1_k127_264744_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
HKD1_k127_264744_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000004562 243.0
HKD1_k127_2657231_0 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 583.0
HKD1_k127_2657231_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 293.0
HKD1_k127_2657231_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 301.0
HKD1_k127_2657231_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000005031 236.0
HKD1_k127_2657231_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000001358 183.0
HKD1_k127_2657231_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000004567 141.0
HKD1_k127_2657231_6 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000001085 135.0
HKD1_k127_2657231_8 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000005846 79.0
HKD1_k127_2657231_9 Flavin containing amine oxidoreductase - - - 0.00002069 51.0
HKD1_k127_2672452_0 PFAM ribonuclease II K01147 - 3.1.13.1 6.398e-221 695.0
HKD1_k127_2672452_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 629.0
HKD1_k127_2672452_2 Receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 276.0
HKD1_k127_2672452_3 ubiE/COQ5 methyltransferase family K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
HKD1_k127_2672452_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003639 248.0
HKD1_k127_2672452_5 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000007641 209.0
HKD1_k127_2672452_6 Methyltransferase FkbM domain - - - 0.00000000000000009835 91.0
HKD1_k127_2699279_0 - K19341 - - 0.00000000000000000000000000000000000000000000000000000007425 203.0
HKD1_k127_2699279_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000004295 185.0
HKD1_k127_2699279_2 NosL K19342 - - 0.0000000000000000000001231 107.0
HKD1_k127_2699279_3 IMP dehydrogenase activity K04767 - - 0.00000000000000000002754 97.0
HKD1_k127_2699279_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000002607 87.0
HKD1_k127_2699279_5 Universal stress protein family K11932 - - 0.000000000001888 73.0
HKD1_k127_2703628_0 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000000000009322 148.0
HKD1_k127_2703628_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000003212 141.0
HKD1_k127_2703628_2 binds to the 23S rRNA K02922 - - 0.00000000000000000000000000000000001496 134.0
HKD1_k127_2703628_3 - - - - 0.00000000000000000000000000000001216 128.0
HKD1_k127_2703628_4 ATP synthase subunit C K02124 - - 0.00000000000000000000000000001121 119.0
HKD1_k127_2703628_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000001278 116.0
HKD1_k127_2716488_0 - - - - 0.000000000000000000000000000000000000000000000000000000007014 217.0
HKD1_k127_2716488_1 Heat shock 70 kDa protein - - - 0.000000001102 68.0
HKD1_k127_2765880_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 594.0
HKD1_k127_2765880_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 371.0
HKD1_k127_2765880_2 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 314.0
HKD1_k127_2765880_3 Glutathione S-transferase, C-terminal domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 292.0
HKD1_k127_2765880_4 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
HKD1_k127_2765880_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000002247 146.0
HKD1_k127_2765880_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000001505 144.0
HKD1_k127_2805795_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.204e-205 671.0
HKD1_k127_2805795_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 5.009e-202 641.0
HKD1_k127_2805795_10 major facilitator superfamily - - - 0.0000000000000000000000000000000000003438 155.0
HKD1_k127_2805795_11 Protein of unknown function (DUF559) - - - 0.000000000000000002259 86.0
HKD1_k127_2805795_13 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00001336 48.0
HKD1_k127_2805795_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 491.0
HKD1_k127_2805795_3 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000008068 243.0
HKD1_k127_2805795_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000008403 237.0
HKD1_k127_2805795_5 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000002615 215.0
HKD1_k127_2805795_6 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000003815 184.0
HKD1_k127_2805795_7 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000005341 183.0
HKD1_k127_2805795_8 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000006465 171.0
HKD1_k127_2805795_9 nucleic acid binding K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000002173 171.0
HKD1_k127_2833671_0 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.00000000000000000000000000000000000000000000000000000002141 205.0
HKD1_k127_2833671_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000002891 75.0
HKD1_k127_287911_0 Ndr family K00433,K01055 - 1.11.1.10,3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000001185 248.0
HKD1_k127_287911_1 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000006488 207.0
HKD1_k127_287911_2 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000004407 139.0
HKD1_k127_287911_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.0000000000001765 71.0
HKD1_k127_2934207_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1763.0
HKD1_k127_2934207_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1053.0
HKD1_k127_2934207_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.611e-279 874.0
HKD1_k127_2934207_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 621.0
HKD1_k127_2944083_0 tail specific protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 540.0
HKD1_k127_2944083_1 oligopeptide transport system permease protein OppB K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 334.0
HKD1_k127_2944083_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 286.0
HKD1_k127_2944083_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000002782 232.0
HKD1_k127_2944083_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000004605 112.0
HKD1_k127_2944083_5 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000003606 78.0
HKD1_k127_2982193_0 PFAM methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 441.0
HKD1_k127_298904_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 318.0
HKD1_k127_298904_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000002705 154.0
HKD1_k127_2993296_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 613.0
HKD1_k127_2993296_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 503.0
HKD1_k127_2993296_10 - - - - 0.000002192 58.0
HKD1_k127_2993296_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
HKD1_k127_2993296_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 288.0
HKD1_k127_2993296_4 Sigma-70 factor, region 1.2 K03086,K03087 GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000001833 215.0
HKD1_k127_2993296_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000001771 188.0
HKD1_k127_2993296_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000002522 126.0
HKD1_k127_2993296_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000001061 103.0
HKD1_k127_2993296_9 Phosphopantetheine attachment site K02078 - - 0.00000000263 61.0
HKD1_k127_3016435_0 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 349.0
HKD1_k127_3016435_1 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000002254 95.0
HKD1_k127_303612_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 322.0
HKD1_k127_3064824_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 468.0
HKD1_k127_3064824_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 454.0
HKD1_k127_3064824_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 428.0
HKD1_k127_3064824_3 DNA topological change K03168,K07479 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
HKD1_k127_3064824_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000003464 190.0
HKD1_k127_3064824_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000002456 79.0
HKD1_k127_3078488_0 serine threonine protein kinase - - - 0.0001081 48.0
HKD1_k127_3089795_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000006538 211.0
HKD1_k127_3089795_1 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000006067 67.0
HKD1_k127_309979_0 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 407.0
HKD1_k127_309979_1 Cell division inhibitor - - - 0.000000000000000000000000000000000000000000000000001472 187.0
HKD1_k127_309979_2 SEC-C Motif Domain Protein - - - 0.00000000000000000000003311 113.0
HKD1_k127_309979_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000005398 60.0
HKD1_k127_3109323_0 Protein of unknown function (DUF1152) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006181 248.0
HKD1_k127_3109323_1 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000000000000003592 186.0
HKD1_k127_3109323_2 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.000000002774 66.0
HKD1_k127_3109323_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0001474 50.0
HKD1_k127_311059_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 547.0
HKD1_k127_311059_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 435.0
HKD1_k127_311059_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000002044 206.0
HKD1_k127_311059_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000001168 137.0
HKD1_k127_311059_4 Periplasmic binding protein K07121 - - 0.000000000000000000001585 108.0
HKD1_k127_311059_5 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000001648 64.0
HKD1_k127_311059_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0005888 47.0
HKD1_k127_3128491_0 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 358.0
HKD1_k127_3128491_1 Belongs to the 'phage' integrase family - - - 0.00000000000000003179 90.0
HKD1_k127_3147468_0 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 306.0
HKD1_k127_3151812_0 4Fe-4S binding domain - - - 1.745e-261 828.0
HKD1_k127_3151812_1 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 559.0
HKD1_k127_3151812_10 Anti-sigma-K factor rskA - - - 0.00000000000000000002477 100.0
HKD1_k127_3151812_11 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.0000000000000000001047 98.0
HKD1_k127_3151812_13 Biotin-lipoyl like - - - 0.000002064 51.0
HKD1_k127_3151812_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 459.0
HKD1_k127_3151812_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 376.0
HKD1_k127_3151812_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 301.0
HKD1_k127_3151812_5 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000003315 220.0
HKD1_k127_3151812_6 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000007419 217.0
HKD1_k127_3151812_7 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002744 206.0
HKD1_k127_3151812_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000003418 144.0
HKD1_k127_3151812_9 cytochrome c oxidase K02862 - - 0.000000000000000000000000000001074 125.0
HKD1_k127_3167285_0 chorismate synthase activity K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 444.0
HKD1_k127_3167285_1 Aminotransferase class I and II K00639,K21784 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 369.0
HKD1_k127_3167285_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000001642 140.0
HKD1_k127_3181436_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 440.0
HKD1_k127_3181436_1 Multicopper oxidase K04753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 334.0
HKD1_k127_3181436_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002775 266.0
HKD1_k127_3181436_3 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000003855 151.0
HKD1_k127_3201790_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 6.886e-223 697.0
HKD1_k127_3201790_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 492.0
HKD1_k127_3201790_2 PFAM Repeat of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 336.0
HKD1_k127_3201790_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
HKD1_k127_3201790_4 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002106 258.0
HKD1_k127_3201790_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.00000000000000000000000000000000000000000000000001724 188.0
HKD1_k127_3201790_6 ThiJ PfpI - - - 0.00000000000000000000000008817 109.0
HKD1_k127_3201790_7 - - - - 0.00000000000000003368 89.0
HKD1_k127_3201790_8 DJ-1/PfpI family - - - 0.0000000000000002711 79.0
HKD1_k127_3201790_9 - - - - 0.00000002259 64.0
HKD1_k127_3222021_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1035.0
HKD1_k127_3222021_1 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 550.0
HKD1_k127_3222021_10 Thioesterase superfamily - - - 0.0000000000000000000001404 104.0
HKD1_k127_3222021_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 366.0
HKD1_k127_3222021_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001048 277.0
HKD1_k127_3222021_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003067 264.0
HKD1_k127_3222021_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001668 245.0
HKD1_k127_3222021_6 Transglycosylase K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000003237 221.0
HKD1_k127_3222021_7 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000007274 168.0
HKD1_k127_3222021_8 - - - - 0.00000000000000000000000000000000000154 154.0
HKD1_k127_3222021_9 Psort location CytoplasmicMembrane, score 10.00 K03310 - - 0.000000000000000000000000007592 111.0
HKD1_k127_3229169_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
HKD1_k127_3229169_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 408.0
HKD1_k127_3229169_10 Di-haem oxidoreductase, putative peroxidase - - - 0.000000006279 59.0
HKD1_k127_3229169_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0000166,GO:0003674,GO:0005215,GO:0005315,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008144,GO:0008150,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0017076,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035303,GO:0035435,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 399.0
HKD1_k127_3229169_3 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 389.0
HKD1_k127_3229169_4 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002777 232.0
HKD1_k127_3229169_5 Imelysin - - - 0.0000000000000000000000000000000000000000000000004133 186.0
HKD1_k127_3229169_6 Thiol oxidoreductase - - - 0.0000000000000000000000000000000000001625 142.0
HKD1_k127_3229169_7 Domain of unknown function (DUF4186) - - - 0.00000000000000000000000000000000004817 138.0
HKD1_k127_3229169_8 Thiol oxidoreductase - - - 0.00000000000000000000000000000000228 134.0
HKD1_k127_3229169_9 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000006598 106.0
HKD1_k127_3291646_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 3.804e-312 996.0
HKD1_k127_3291646_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000004188 139.0
HKD1_k127_3291646_2 Major facilitator superfamily - - - 0.0000000000000000000006636 96.0
HKD1_k127_3291646_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000006238 94.0
HKD1_k127_3291646_4 Transporter K08368 - - 0.0000000002065 65.0
HKD1_k127_336481_0 Aminotransferase class-III - - - 1.991e-194 618.0
HKD1_k127_336481_1 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002539 249.0
HKD1_k127_336481_2 FAD binding domain - - - 0.000000000000000000000000001081 125.0
HKD1_k127_336481_3 Belongs to the UPF0312 family - - - 0.0000000004135 69.0
HKD1_k127_3370115_0 Nitrous oxide reductase K00376 - 1.7.2.4 1.697e-295 921.0
HKD1_k127_3370115_1 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 362.0
HKD1_k127_3370115_2 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005591 280.0
HKD1_k127_3370115_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000002377 231.0
HKD1_k127_3370115_4 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0005777 48.0
HKD1_k127_3370115_5 - K19341 - - 0.0006972 44.0
HKD1_k127_3374784_0 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001754 274.0
HKD1_k127_3374784_1 - - - - 0.0000000000000000000000000000000000000000000000002265 178.0
HKD1_k127_3374784_2 - - - - 0.0000000000000000000000000000000000000000000000007763 175.0
HKD1_k127_3374784_3 - - - - 0.0000000000000000000000000000000000004098 140.0
HKD1_k127_3374784_4 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000002985 72.0
HKD1_k127_3381651_0 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 437.0
HKD1_k127_3381651_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 385.0
HKD1_k127_3381651_2 Tetratricopeptide repeat - - - 0.0000000000000000000001454 106.0
HKD1_k127_3387158_0 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 416.0
HKD1_k127_3395942_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 414.0
HKD1_k127_3395942_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 408.0
HKD1_k127_3395942_10 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000001531 107.0
HKD1_k127_3395942_11 COG1145 Ferredoxin - - - 0.0000000000000000001298 98.0
HKD1_k127_3395942_12 regulatory protein, arsR - - - 0.000000000000000008964 86.0
HKD1_k127_3395942_13 Transcriptional regulator ArsR family - - - 0.00000000000002125 79.0
HKD1_k127_3395942_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
HKD1_k127_3395942_3 Chalcone and stilbene synthases, N-terminal domain K16167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 340.0
HKD1_k127_3395942_4 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 340.0
HKD1_k127_3395942_5 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 322.0
HKD1_k127_3395942_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 269.0
HKD1_k127_3395942_7 protein conserved in bacteria K16168 - - 0.000000000000000000000000000000000000000000001953 171.0
HKD1_k127_3395942_8 DoxX K15977 - - 0.000000000000000000000000000000000000000000008028 167.0
HKD1_k127_3395942_9 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.00000000000000000000000000000002136 130.0
HKD1_k127_3401337_0 DisA bacterial checkpoint controller nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 235.0
HKD1_k127_3401337_1 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000000000000000000000000000001128 205.0
HKD1_k127_3401337_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000004468 188.0
HKD1_k127_3401337_3 acetyltransferase - - - 0.0000000000000000000000000000004846 128.0
HKD1_k127_3401337_4 Ecdysteroid kinase - - - 0.000000000000000001017 93.0
HKD1_k127_3401337_5 - - - - 0.00000000000003003 81.0
HKD1_k127_3401337_6 - - - - 0.00004836 53.0
HKD1_k127_3401488_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.093e-213 672.0
HKD1_k127_3401488_1 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 439.0
HKD1_k127_3401488_2 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000003765 121.0
HKD1_k127_3401488_3 - - - - 0.00000033 57.0
HKD1_k127_3419304_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 587.0
HKD1_k127_3419304_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 549.0
HKD1_k127_3419304_2 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 466.0
HKD1_k127_3419304_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 351.0
HKD1_k127_3419310_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
HKD1_k127_3419310_1 - - - - 0.00000000000000000000000000000000000000000000000000002296 190.0
HKD1_k127_3419310_2 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000000000000000002276 165.0
HKD1_k127_3419310_3 - - - - 0.0000000000000000000000000000000001076 138.0
HKD1_k127_3419310_5 Hint domain - - - 0.0003097 51.0
HKD1_k127_3431950_0 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 362.0
HKD1_k127_3431950_1 PFAM ABC transporter related K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 335.0
HKD1_k127_3431950_2 - - - - 0.0000000000000000000000000000000000004535 151.0
HKD1_k127_3444145_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1731.0
HKD1_k127_3444145_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 597.0
HKD1_k127_3444145_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 481.0
HKD1_k127_3444145_3 S-acyltransferase activity K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 387.0
HKD1_k127_3444145_4 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002363 286.0
HKD1_k127_3444145_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000006422 186.0
HKD1_k127_346531_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 393.0
HKD1_k127_346531_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009193 276.0
HKD1_k127_346531_2 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000002615 135.0
HKD1_k127_346531_3 energy transducer activity K03832 - - 0.0000005263 51.0
HKD1_k127_3496128_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.864e-297 937.0
HKD1_k127_3496128_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 591.0
HKD1_k127_3496128_10 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.00000000000000002177 85.0
HKD1_k127_3496128_2 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 522.0
HKD1_k127_3496128_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 502.0
HKD1_k127_3496128_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 499.0
HKD1_k127_3496128_5 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 415.0
HKD1_k127_3496128_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001038 273.0
HKD1_k127_3496128_7 haloacid dehalogenase-like hydrolase K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000005038 269.0
HKD1_k127_3496128_8 helix_turn_helix, mercury resistance - - - 0.000000000000000000000005605 104.0
HKD1_k127_3496128_9 TonB C terminal K03832 - - 0.000000000000000000002029 106.0
HKD1_k127_3511552_0 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000002034 155.0
HKD1_k127_3524784_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 503.0
HKD1_k127_3524784_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000001641 108.0
HKD1_k127_3524784_2 beta-lactamase domain protein - - - 0.000000006356 57.0
HKD1_k127_3538150_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K18660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 550.0
HKD1_k127_3538150_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000001674 170.0
HKD1_k127_3538158_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 388.0
HKD1_k127_3538158_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 308.0
HKD1_k127_3538158_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001126 241.0
HKD1_k127_3540764_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 240.0
HKD1_k127_3540764_1 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000007898 156.0
HKD1_k127_3540764_2 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000003189 127.0
HKD1_k127_3552939_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 2.208e-208 666.0
HKD1_k127_3552939_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 523.0
HKD1_k127_3552939_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 312.0
HKD1_k127_3552939_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000961 237.0
HKD1_k127_3552939_4 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000004591 182.0
HKD1_k127_3552939_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000001777 163.0
HKD1_k127_3552939_6 - - - - 0.000001254 58.0
HKD1_k127_3571139_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 515.0
HKD1_k127_3571139_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 499.0
HKD1_k127_3571139_2 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 412.0
HKD1_k127_3571139_3 Major Facilitator K08196,K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 394.0
HKD1_k127_3571139_4 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 385.0
HKD1_k127_3571139_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000007614 201.0
HKD1_k127_3571139_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000002095 174.0
HKD1_k127_3571139_7 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000001573 139.0
HKD1_k127_3571139_8 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000007768 112.0
HKD1_k127_3571139_9 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000007925 108.0
HKD1_k127_3617657_0 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002345 272.0
HKD1_k127_3617657_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000001496 225.0
HKD1_k127_3617657_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000002896 147.0
HKD1_k127_36198_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1025.0
HKD1_k127_36198_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 552.0
HKD1_k127_36198_2 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 364.0
HKD1_k127_36198_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 298.0
HKD1_k127_36198_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000004335 245.0
HKD1_k127_3676739_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000002701 97.0
HKD1_k127_3676739_1 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000001862 66.0
HKD1_k127_3676739_2 - - - - 0.0000001384 63.0
HKD1_k127_3676739_4 Glycosyltransferase like family 2 - - - 0.00002839 55.0
HKD1_k127_3677528_0 PFAM ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 481.0
HKD1_k127_3677528_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 348.0
HKD1_k127_3677528_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000008774 190.0
HKD1_k127_3677528_3 cyclic nucleotide binding K01420,K10716,K10914,K16922 - - 0.000000000000000000000000000000000000000000001257 174.0
HKD1_k127_3677528_4 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000403 148.0
HKD1_k127_3677528_5 COG1651 Protein-disulfide isomerase K21990 - - 0.00000000000000000000000000018 122.0
HKD1_k127_3677528_6 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.0000000000000000000000001318 124.0
HKD1_k127_3677528_7 Thioredoxin - - - 0.00000000000002483 76.0
HKD1_k127_3677528_8 Protein of unknown function (DUF2892) - - - 0.000000000002569 69.0
HKD1_k127_3688077_0 PFAM Sugar isomerase (SIS) - - - 2.6e-247 764.0
HKD1_k127_3688077_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 490.0
HKD1_k127_3689929_0 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000000000266 210.0
HKD1_k127_3705226_0 Heat shock 70 kDa protein K04043 - - 1.994e-267 837.0
HKD1_k127_3705226_1 Elongation factor Tu domain 2 K02355 - - 2.908e-222 708.0
HKD1_k127_3705226_2 Binds the 23S rRNA K02909 - - 0.00000000000000000000006085 99.0
HKD1_k127_3705226_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000005802 83.0
HKD1_k127_3705226_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000001305 59.0
HKD1_k127_3706858_0 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 468.0
HKD1_k127_3706858_1 'glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 432.0
HKD1_k127_3706858_2 DNA excision - - - 0.0000000000000000000000000000000000003518 147.0
HKD1_k127_3708058_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 295.0
HKD1_k127_3708058_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001699 211.0
HKD1_k127_3708058_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000001735 175.0
HKD1_k127_3708058_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000002314 162.0
HKD1_k127_3708058_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000003296 50.0
HKD1_k127_3733788_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0 1350.0
HKD1_k127_3733788_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0 1058.0
HKD1_k127_3733788_2 Malate synthase K01638 - 2.3.3.9 2.198e-295 955.0
HKD1_k127_3733788_3 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 532.0
HKD1_k127_3733788_4 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001876 280.0
HKD1_k127_3733788_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002496 285.0
HKD1_k127_3733788_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000001041 90.0
HKD1_k127_3733788_7 Protein of unknown function (DUF2934) - - - 0.00000000004284 65.0
HKD1_k127_3753227_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001258 230.0
HKD1_k127_3779257_0 AsmA-like C-terminal region - - - 0.0000000000004922 82.0
HKD1_k127_3792139_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 488.0
HKD1_k127_3792139_1 ADP-glyceromanno-heptose 6-epimerase activity K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 320.0
HKD1_k127_3792139_2 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
HKD1_k127_3792139_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
HKD1_k127_385846_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 486.0
HKD1_k127_385846_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 477.0
HKD1_k127_385846_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
HKD1_k127_385846_3 4Fe-4S single cluster domain K22227 - - 0.00000000000000000000000000000000004488 135.0
HKD1_k127_385846_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000006002 130.0
HKD1_k127_385846_5 PFAM Colicin V production protein K03558 - - 0.0000000005937 68.0
HKD1_k127_3896471_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 484.0
HKD1_k127_3896471_1 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 388.0
HKD1_k127_3896471_10 YCII-related domain - - - 0.0000000000000000000000000000000000009994 144.0
HKD1_k127_3896471_11 TQO small subunit DoxD K15977 - - 0.000000000000000008422 89.0
HKD1_k127_3896471_12 Leucine carboxyl methyltransferase - - - 0.00003428 49.0
HKD1_k127_3896471_2 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 316.0
HKD1_k127_3896471_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 321.0
HKD1_k127_3896471_4 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 293.0
HKD1_k127_3896471_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000001082 183.0
HKD1_k127_3896471_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000917 164.0
HKD1_k127_3896471_7 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000001655 153.0
HKD1_k127_3896471_8 RibD C-terminal domain - - - 0.000000000000000000000000000000000000009484 151.0
HKD1_k127_3896471_9 PFAM Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000002724 158.0
HKD1_k127_3897785_0 Predicted ATPase of the ABC class - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 625.0
HKD1_k127_3897785_1 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 296.0
HKD1_k127_3897785_2 Glycosyl transferase family 11 - - - 0.0000000000000000000000000000000000000000000000000000000002995 215.0
HKD1_k127_3897785_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000006149 213.0
HKD1_k127_3897785_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000123 120.0
HKD1_k127_3897785_5 Methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000002299 96.0
HKD1_k127_3897785_6 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000002419 70.0
HKD1_k127_3923806_0 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000000000000000000000000000000000000000001149 242.0
HKD1_k127_3923806_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000006863 184.0
HKD1_k127_3923806_2 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000005064 141.0
HKD1_k127_3923806_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000002172 89.0
HKD1_k127_3923806_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00003745 46.0
HKD1_k127_3933975_0 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 450.0
HKD1_k127_3933975_1 DNA polymerase beta K07076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 397.0
HKD1_k127_3933975_2 Beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003297 248.0
HKD1_k127_3933975_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000009142 196.0
HKD1_k127_3937343_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 470.0
HKD1_k127_3937343_1 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000000008002 93.0
HKD1_k127_3958742_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.295e-254 805.0
HKD1_k127_3958742_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 4.523e-221 704.0
HKD1_k127_3958742_2 Sulfatase - - - 0.000000000000000000000000000000000000001968 162.0
HKD1_k127_3958742_3 - - - - 0.000000000000000000000000000000006399 134.0
HKD1_k127_3958742_4 - - - - 0.000000000002792 68.0
HKD1_k127_3959606_0 Alpha beta hydrolase K00433,K01055 - 1.11.1.10,3.1.1.24 0.00000000000000000000000000000000000000000000000000000002206 206.0
HKD1_k127_3959606_1 Haloacid dehalogenase-like hydrolase K02566 - - 0.000000000000000000000000000000000000000000000000007102 190.0
HKD1_k127_3959606_2 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000000000000000000002249 95.0
HKD1_k127_3982366_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 319.0
HKD1_k127_3982366_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000002259 226.0
HKD1_k127_3982366_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000001225 82.0
HKD1_k127_3982366_3 Glycine zipper - - - 0.000000000001834 79.0
HKD1_k127_4007859_0 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 427.0
HKD1_k127_4007859_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 430.0
HKD1_k127_4007859_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 420.0
HKD1_k127_4007859_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 348.0
HKD1_k127_4007859_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 341.0
HKD1_k127_4007859_5 Belongs to the ClpX chaperone family K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 331.0
HKD1_k127_4007859_6 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 320.0
HKD1_k127_4007859_7 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 316.0
HKD1_k127_4007859_8 isomerase K03770 - 5.2.1.8 0.00000000000000886 86.0
HKD1_k127_4017529_0 Belongs to the MCM family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 392.0
HKD1_k127_4017529_1 COG1522 Transcriptional regulators K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 361.0
HKD1_k127_4017529_2 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000000000000000000000000000000371 186.0
HKD1_k127_4048727_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 1.404e-204 645.0
HKD1_k127_4048727_1 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 557.0
HKD1_k127_4048727_2 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 419.0
HKD1_k127_4048727_3 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 312.0
HKD1_k127_4048727_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000006441 214.0
HKD1_k127_4048727_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003675 187.0
HKD1_k127_4048727_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000002295 173.0
HKD1_k127_4048727_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000005612 161.0
HKD1_k127_4048727_8 Protein of unknown function (DUF3891) - - - 0.000000000000000000000000000000343 134.0
HKD1_k127_4048727_9 methyltransferase - - - 0.000000000000001376 87.0
HKD1_k127_4051393_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 448.0
HKD1_k127_4051393_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 427.0
HKD1_k127_4051393_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 391.0
HKD1_k127_4051393_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001066 237.0
HKD1_k127_4051393_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000004079 188.0
HKD1_k127_4051393_5 - - - - 0.00000000000000000003292 101.0
HKD1_k127_4051393_6 F420H(2)-dependent quinone reductase - - - 0.0000000000000000001556 93.0
HKD1_k127_4051393_8 Iron-containing redox enzyme - - - 0.0009135 49.0
HKD1_k127_4083492_0 nucleotidase K01082 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0004441,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009628,GO:0009651,GO:0009987,GO:0016053,GO:0016311,GO:0016312,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0023052,GO:0035556,GO:0042538,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046030,GO:0046394,GO:0048015,GO:0048017,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052829,GO:0065007,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
HKD1_k127_4083492_1 aldo-keto reductase (NADP) activity K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000001458 165.0
HKD1_k127_4083492_2 Aldo/keto reductase family - - - 0.0000000000000000000006507 101.0
HKD1_k127_4099416_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000146 236.0
HKD1_k127_4099416_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000002134 227.0
HKD1_k127_4099416_2 - - - - 0.00000000000000000000000000000000000000000000002014 177.0
HKD1_k127_4099416_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000004254 123.0
HKD1_k127_4109995_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 462.0
HKD1_k127_4109995_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
HKD1_k127_4109995_2 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008854 257.0
HKD1_k127_4109995_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002021 248.0
HKD1_k127_4109995_4 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001747 241.0
HKD1_k127_4109995_5 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
HKD1_k127_4109995_6 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000001483 208.0
HKD1_k127_4109995_7 - - - - 0.0000000000000000004769 94.0
HKD1_k127_4111699_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 587.0
HKD1_k127_4111699_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
HKD1_k127_4111699_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000003386 116.0
HKD1_k127_4114499_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.174e-311 967.0
HKD1_k127_4114499_1 FAD linked oxidases, C-terminal domain K06911 - - 0.0000000000000000000000000001078 123.0
HKD1_k127_4115796_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 6.909e-252 782.0
HKD1_k127_4115796_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 581.0
HKD1_k127_4115796_10 of nitrite reductase and ring-hydroxylating K05710 - - 0.00000000000000000000001911 102.0
HKD1_k127_4115796_11 transcriptional regulator - - - 0.000000000000000003213 89.0
HKD1_k127_4115796_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 576.0
HKD1_k127_4115796_3 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 385.0
HKD1_k127_4115796_4 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
HKD1_k127_4115796_5 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 316.0
HKD1_k127_4115796_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000002576 246.0
HKD1_k127_4115796_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000003464 202.0
HKD1_k127_4115796_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000001895 153.0
HKD1_k127_4115796_9 - - - - 0.0000000000000000000000000004259 116.0
HKD1_k127_4129777_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 582.0
HKD1_k127_4129777_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 480.0
HKD1_k127_4129777_2 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 409.0
HKD1_k127_4129777_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 400.0
HKD1_k127_4129777_4 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
HKD1_k127_4129777_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002684 285.0
HKD1_k127_4129777_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000008236 154.0
HKD1_k127_4129777_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000003145 91.0
HKD1_k127_4133713_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 325.0
HKD1_k127_4133713_1 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
HKD1_k127_4133713_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 286.0
HKD1_k127_4133713_3 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007265 278.0
HKD1_k127_4133713_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000002124 196.0
HKD1_k127_4133713_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000003862 193.0
HKD1_k127_4133713_6 Phospholipid N-methyltransferase - - - 0.000000000000000000000000000000000000009149 152.0
HKD1_k127_4151476_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 391.0
HKD1_k127_4151476_2 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000000003659 114.0
HKD1_k127_4154171_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.648e-205 654.0
HKD1_k127_4154171_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
HKD1_k127_4154171_2 Glycoprotease family - - - 0.00000000000000000000000000000000000000000001184 171.0
HKD1_k127_4154171_3 ACT domain K01653 - 2.2.1.6 0.0000000000000000000002394 98.0
HKD1_k127_4167896_0 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.00000000000000000000000000000000000000003404 167.0
HKD1_k127_4167896_1 Lysin motif - - - 0.000000000000007969 82.0
HKD1_k127_4167896_2 lipolytic protein G-D-S-L family - - - 0.0000000003701 70.0
HKD1_k127_4167896_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000002989 65.0
HKD1_k127_4167896_4 Polysaccharide biosynthesis protein - - - 0.0000002829 57.0
HKD1_k127_418447_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 424.0
HKD1_k127_418447_1 Histidine kinase K02482,K18143 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000203 198.0
HKD1_k127_418447_2 Transglycosylase associated protein - - - 0.0000000000000000000000007995 106.0
HKD1_k127_418447_3 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000004926 104.0
HKD1_k127_4227925_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 8.471e-313 973.0
HKD1_k127_4227925_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.075e-203 651.0
HKD1_k127_4227925_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
HKD1_k127_4227925_11 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000002655 167.0
HKD1_k127_4227925_12 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000001103 165.0
HKD1_k127_4227925_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000004069 149.0
HKD1_k127_4227925_14 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000002962 146.0
HKD1_k127_4227925_15 NUDIX domain - - - 0.000000000000000000000000000005052 126.0
HKD1_k127_4227925_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 539.0
HKD1_k127_4227925_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 440.0
HKD1_k127_4227925_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 344.0
HKD1_k127_4227925_5 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
HKD1_k127_4227925_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
HKD1_k127_4227925_7 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003652 262.0
HKD1_k127_4227925_8 PFAM ABC transporter related K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000001716 225.0
HKD1_k127_4227925_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000008513 214.0
HKD1_k127_422872_0 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000002867 287.0
HKD1_k127_422872_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000006468 215.0
HKD1_k127_422872_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000008784 147.0
HKD1_k127_422872_3 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000006685 143.0
HKD1_k127_422872_4 Heavy-metal resistance - - - 0.000000009479 62.0
HKD1_k127_422872_5 Putative zinc-finger - - - 0.00001191 54.0
HKD1_k127_4239873_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 574.0
HKD1_k127_4239873_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000002213 258.0
HKD1_k127_4239873_2 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000002188 166.0
HKD1_k127_4239873_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000001807 160.0
HKD1_k127_4242382_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001164 301.0
HKD1_k127_4242382_1 GAF domain - - - 0.00000000000000000000000000000000000000000000001425 195.0
HKD1_k127_4256000_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.0 1059.0
HKD1_k127_4256000_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 593.0
HKD1_k127_4256000_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006172 261.0
HKD1_k127_4256000_11 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000002977 221.0
HKD1_k127_4256000_12 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000539 177.0
HKD1_k127_4256000_13 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000000000000000000000000000000000000000005847 173.0
HKD1_k127_4256000_14 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000002321 162.0
HKD1_k127_4256000_15 - - - - 0.0000000000000000000000000000000000024 149.0
HKD1_k127_4256000_16 PFAM Acetyltransferase (GNAT) family K03830 - - 0.0000000000000000000000000000003657 128.0
HKD1_k127_4256000_17 Acetyltransferase (GNAT) domain K03830 - - 0.000000000000000000000000000001062 127.0
HKD1_k127_4256000_18 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000001648 127.0
HKD1_k127_4256000_19 SpoIIAA-like - - - 0.0000000000000000000000000001091 121.0
HKD1_k127_4256000_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 452.0
HKD1_k127_4256000_20 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000004142 93.0
HKD1_k127_4256000_21 Cytochrome oxidase maturation protein - - - 0.00000000000525 70.0
HKD1_k127_4256000_3 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 465.0
HKD1_k127_4256000_4 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 410.0
HKD1_k127_4256000_5 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 385.0
HKD1_k127_4256000_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 355.0
HKD1_k127_4256000_7 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 336.0
HKD1_k127_4256000_8 Methyltransferase type 11 K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 301.0
HKD1_k127_4256000_9 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001822 282.0
HKD1_k127_4266261_0 Histidine kinase K07646 - 2.7.13.3 8.611e-214 677.0
HKD1_k127_4266261_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000001049 244.0
HKD1_k127_4266261_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000008236 205.0
HKD1_k127_4270792_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002284 267.0
HKD1_k127_4270792_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000468 255.0
HKD1_k127_4270792_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000008037 164.0
HKD1_k127_4270792_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000002855 115.0
HKD1_k127_4270792_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000002054 96.0
HKD1_k127_4270792_5 Heavy-metal resistance - - - 0.0000006321 57.0
HKD1_k127_4270792_6 Heavy-metal resistance - - - 0.0002285 50.0
HKD1_k127_4292311_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 436.0
HKD1_k127_4292311_1 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
HKD1_k127_4292311_2 Glycosyl transferases group 1 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 349.0
HKD1_k127_4292311_3 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 337.0
HKD1_k127_4292311_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000001141 174.0
HKD1_k127_4292311_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000002412 151.0
HKD1_k127_4292311_6 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000009435 135.0
HKD1_k127_4292311_7 O-Antigen ligase - - - 0.0000000000000000000000001515 113.0
HKD1_k127_4292311_8 glycosyl transferase family 2 K00786 - - 0.000000000000000000000003686 115.0
HKD1_k127_4296262_0 Cation transporter/ATPase, N-terminus K01531,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 0.0 1318.0
HKD1_k127_4296262_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 375.0
HKD1_k127_4296262_10 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000002791 171.0
HKD1_k127_4296262_11 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000002238 157.0
HKD1_k127_4296262_12 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000005642 146.0
HKD1_k127_4296262_13 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000006085 122.0
HKD1_k127_4296262_14 - - - - 0.00000000000000000000000004503 111.0
HKD1_k127_4296262_15 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000002421 93.0
HKD1_k127_4296262_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000003859 79.0
HKD1_k127_4296262_17 ECF sigma factor K03088 - - 0.00000000000001899 75.0
HKD1_k127_4296262_18 Anti-sigma-K factor rskA - - - 0.0000000000002703 78.0
HKD1_k127_4296262_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000001598 69.0
HKD1_k127_4296262_2 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 347.0
HKD1_k127_4296262_20 antibiotic catabolic process - - - 0.0005953 46.0
HKD1_k127_4296262_3 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001227 256.0
HKD1_k127_4296262_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
HKD1_k127_4296262_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002451 244.0
HKD1_k127_4296262_6 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000008401 224.0
HKD1_k127_4296262_7 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000003834 200.0
HKD1_k127_4296262_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000006295 175.0
HKD1_k127_4296262_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000121 171.0
HKD1_k127_4309073_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.722e-242 758.0
HKD1_k127_4309073_1 NurA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 336.0
HKD1_k127_4309073_2 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000001062 206.0
HKD1_k127_4309073_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000001102 173.0
HKD1_k127_4309073_4 HAS barrel domain - - - 0.000000000000000000000000000000000001441 148.0
HKD1_k127_4335244_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K01507,K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 499.0
HKD1_k127_4335244_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 412.0
HKD1_k127_4335244_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000004826 213.0
HKD1_k127_4335244_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000003796 154.0
HKD1_k127_4346071_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1034.0
HKD1_k127_4346071_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.03e-311 967.0
HKD1_k127_4346071_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 447.0
HKD1_k127_4346071_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 428.0
HKD1_k127_4346071_12 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 362.0
HKD1_k127_4346071_13 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 331.0
HKD1_k127_4346071_14 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 311.0
HKD1_k127_4346071_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 276.0
HKD1_k127_4346071_16 Helix-hairpin-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 280.0
HKD1_k127_4346071_17 methyltransferase K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
HKD1_k127_4346071_18 phosphate transporter K16331 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000002729 206.0
HKD1_k127_4346071_19 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000003812 179.0
HKD1_k127_4346071_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 2.294e-264 833.0
HKD1_k127_4346071_20 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000004278 169.0
HKD1_k127_4346071_21 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000002483 158.0
HKD1_k127_4346071_22 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000002453 156.0
HKD1_k127_4346071_23 - - - - 0.0000000000000000000009754 100.0
HKD1_k127_4346071_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 6.011e-228 711.0
HKD1_k127_4346071_4 Amino acid permease K16238 - - 3.068e-207 667.0
HKD1_k127_4346071_5 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 2.477e-206 659.0
HKD1_k127_4346071_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 584.0
HKD1_k127_4346071_7 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 558.0
HKD1_k127_4346071_8 transferase activity, transferring glycosyl groups K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 527.0
HKD1_k127_4346071_9 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 445.0
HKD1_k127_4346791_0 2 heme-binding sites K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 482.0
HKD1_k127_4346791_1 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 467.0
HKD1_k127_4346791_2 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.000000000000000001511 101.0
HKD1_k127_4346791_3 Domain of unknown function (DUF4405) - - - 0.00000001708 60.0
HKD1_k127_4357881_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD1_k127_4366091_0 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1890.0
HKD1_k127_4366091_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 353.0
HKD1_k127_4368082_0 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
HKD1_k127_4368082_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000001104 251.0
HKD1_k127_4368082_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000002978 233.0
HKD1_k127_4368082_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000004622 109.0
HKD1_k127_4411074_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 508.0
HKD1_k127_4411074_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 370.0
HKD1_k127_4411074_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000004733 103.0
HKD1_k127_4411074_12 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000009924 91.0
HKD1_k127_4411074_13 - - - - 0.00000000000000001685 82.0
HKD1_k127_4411074_14 - - - - 0.0000000000000000304 81.0
HKD1_k127_4411074_15 - - - - 0.00000000000000138 76.0
HKD1_k127_4411074_17 - - - - 0.000000000000007021 83.0
HKD1_k127_4411074_18 Cell wall-associated hydrolase - - - 0.00000000000003974 73.0
HKD1_k127_4411074_19 - - - - 0.00000000000391 67.0
HKD1_k127_4411074_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009852 264.0
HKD1_k127_4411074_20 - - - - 0.0000000005226 60.0
HKD1_k127_4411074_21 ORF located using Blastx - - - 0.000000001039 59.0
HKD1_k127_4411074_22 Vacuole effluxer Atg22 like K06902 - - 0.00000001284 57.0
HKD1_k127_4411074_24 - - - - 0.0000002535 56.0
HKD1_k127_4411074_25 - - - - 0.000004629 49.0
HKD1_k127_4411074_3 - - - - 0.00000000000000000000000000000000000000000000001478 171.0
HKD1_k127_4411074_4 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000002367 142.0
HKD1_k127_4411074_5 - - - - 0.0000000000000000000000000000001095 126.0
HKD1_k127_4411074_7 - - - - 0.00000000000000000000000001599 110.0
HKD1_k127_4411074_8 - - - - 0.000000000000000000000004918 108.0
HKD1_k127_4411074_9 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000006293 106.0
HKD1_k127_4412476_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.964e-253 800.0
HKD1_k127_4412476_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 570.0
HKD1_k127_4412476_10 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000262 210.0
HKD1_k127_4412476_11 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
HKD1_k127_4412476_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000001541 204.0
HKD1_k127_4412476_13 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000009616 195.0
HKD1_k127_4412476_14 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000000000003062 177.0
HKD1_k127_4412476_15 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000008924 177.0
HKD1_k127_4412476_16 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000001616 175.0
HKD1_k127_4412476_17 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000002454 169.0
HKD1_k127_4412476_18 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000004503 167.0
HKD1_k127_4412476_19 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000001255 146.0
HKD1_k127_4412476_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 572.0
HKD1_k127_4412476_20 Surface antigen K07277 - - 0.000000000000000000000000000002551 129.0
HKD1_k127_4412476_21 Thioredoxin-like - - - 0.00000000000000000000000000004455 123.0
HKD1_k127_4412476_22 Domain of unknown function (DUF4442) K02614 - - 0.00000000000000000000002799 104.0
HKD1_k127_4412476_23 Regulatory protein, FmdB family - - - 0.000000008316 59.0
HKD1_k127_4412476_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 509.0
HKD1_k127_4412476_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 474.0
HKD1_k127_4412476_5 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 407.0
HKD1_k127_4412476_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
HKD1_k127_4412476_7 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 359.0
HKD1_k127_4412476_8 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
HKD1_k127_4412476_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002371 264.0
HKD1_k127_4421022_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 520.0
HKD1_k127_4421022_1 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 426.0
HKD1_k127_4421022_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000007767 252.0
HKD1_k127_4421022_3 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000003254 211.0
HKD1_k127_4421022_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000004557 118.0
HKD1_k127_4421022_5 protein conserved in bacteria - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000001946 93.0
HKD1_k127_4421022_6 Transcriptional regulator - - - 0.000002144 56.0
HKD1_k127_4421709_0 Putative Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 409.0
HKD1_k127_4423446_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
HKD1_k127_4423446_1 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000003809 106.0
HKD1_k127_4423446_2 RHS Repeat - - - 0.000000000000000000000008699 106.0
HKD1_k127_4448075_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 440.0
HKD1_k127_4448075_1 involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009464 274.0
HKD1_k127_4448075_2 TupA-like ATPgrasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000001769 247.0
HKD1_k127_4448075_3 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000000000000000000008375 196.0
HKD1_k127_4448075_4 Lipase (class 3) K01046 - 3.1.1.3 0.000000000000000000003101 106.0
HKD1_k127_4448075_5 Neurotransmitter-gated ion-channel ligand binding domain - - - 0.000000000000000000003949 97.0
HKD1_k127_4453587_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001133 223.0
HKD1_k127_4453587_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000008363 207.0
HKD1_k127_4453587_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000009814 199.0
HKD1_k127_4453587_3 pathogenesis - - - 0.00000000000000000000000000000000001409 156.0
HKD1_k127_4453587_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00001745 55.0
HKD1_k127_4453587_6 PFAM Glycosyl transferases group 1 - - - 0.0007138 53.0
HKD1_k127_4467523_0 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 437.0
HKD1_k127_4467523_1 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000006261 201.0
HKD1_k127_4517438_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 392.0
HKD1_k127_4517438_1 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000002313 154.0
HKD1_k127_4517438_2 PFAM SMP-30 Gluconolaconase - - - 0.00000001066 61.0
HKD1_k127_4517438_3 Membrane transport protein K07088 - - 0.00008419 48.0
HKD1_k127_4547748_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.053e-209 657.0
HKD1_k127_4547748_1 Belongs to the TPP enzyme family K01568 - 4.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 584.0
HKD1_k127_4547748_2 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 339.0
HKD1_k127_4547748_3 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 325.0
HKD1_k127_4547748_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000003361 77.0
HKD1_k127_4547748_5 cAMP biosynthetic process K03641 - - 0.0002882 52.0
HKD1_k127_4556083_0 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
HKD1_k127_4556083_1 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000003609 211.0
HKD1_k127_4556083_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000004864 202.0
HKD1_k127_4556083_3 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000008208 189.0
HKD1_k127_4556083_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000003756 71.0
HKD1_k127_4559519_0 heme ABC exporter, ATP-binding protein CcmA K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000007563 226.0
HKD1_k127_4559519_1 3-beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.000000000000000000000000000000000000000000000000000000000244 215.0
HKD1_k127_4614231_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1052.0
HKD1_k127_4614231_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 386.0
HKD1_k127_4614231_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000163 158.0
HKD1_k127_4614231_3 Dodecin - - - 0.000000000000004616 76.0
HKD1_k127_4639784_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 461.0
HKD1_k127_4639784_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001981 276.0
HKD1_k127_4639784_2 HlyD family secretion protein K07798,K15727 - - 0.00000000000000000000000000000000000000000001088 175.0
HKD1_k127_4639784_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.000000000000000000000000000000000000003264 154.0
HKD1_k127_4642541_0 Aminotransferase, class I K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 544.0
HKD1_k127_4642541_1 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 419.0
HKD1_k127_4642541_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000005403 177.0
HKD1_k127_4642541_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000002426 171.0
HKD1_k127_4642541_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000009011 85.0
HKD1_k127_4656886_0 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
HKD1_k127_4656886_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
HKD1_k127_4656886_2 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 273.0
HKD1_k127_4656886_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000009627 188.0
HKD1_k127_4656886_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000001528 130.0
HKD1_k127_4656886_5 xyloglucan:xyloglucosyl transferase activity - - - 0.0004873 52.0
HKD1_k127_4668298_0 signal-transduction protein containing cAMP-binding and CBS domains K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000000000000000000000000001179 143.0
HKD1_k127_4668298_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000007001 141.0
HKD1_k127_4668559_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 446.0
HKD1_k127_4668559_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004276 272.0
HKD1_k127_4668559_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000429 170.0
HKD1_k127_4668559_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000002632 152.0
HKD1_k127_4668559_4 ACT domain K00928 - 2.7.2.4 0.0000000000000000000008278 96.0
HKD1_k127_4731368_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
HKD1_k127_4731368_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000009305 207.0
HKD1_k127_4731368_2 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000000000000000000000001318 187.0
HKD1_k127_4731368_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000003981 174.0
HKD1_k127_4731368_4 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000003156 122.0
HKD1_k127_4731368_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.00001617 50.0
HKD1_k127_4736030_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 426.0
HKD1_k127_4736030_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 312.0
HKD1_k127_4736030_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000006072 68.0
HKD1_k127_4774949_0 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000007941 226.0
HKD1_k127_4774949_1 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000000000004562 181.0
HKD1_k127_4792560_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.813e-241 754.0
HKD1_k127_4792560_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 466.0
HKD1_k127_4792560_2 plastoquinone (Complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 365.0
HKD1_k127_4792560_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
HKD1_k127_4792560_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
HKD1_k127_4792560_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000001972 218.0
HKD1_k127_4792560_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000006509 221.0
HKD1_k127_4792560_7 Hydrogenase 4 membrane K12140 - - 0.0000000000001579 79.0
HKD1_k127_4792560_8 Major facilitator Superfamily K08151,K08153 - - 0.0004631 45.0
HKD1_k127_4792560_9 cellular response to DNA damage stimulus - - - 0.0005997 43.0
HKD1_k127_4807454_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.503e-251 783.0
HKD1_k127_4807454_1 carboxylase, biotin carboxylase K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 545.0
HKD1_k127_4807454_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 513.0
HKD1_k127_4807454_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 329.0
HKD1_k127_4807454_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000005475 237.0
HKD1_k127_4807454_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000002329 227.0
HKD1_k127_4807454_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000006026 172.0
HKD1_k127_4807454_8 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.000000000000000000000008718 108.0
HKD1_k127_4807454_9 - - - - 0.00000000000000001817 90.0
HKD1_k127_4840760_0 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000000000001662 192.0
HKD1_k127_4840760_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000008332 123.0
HKD1_k127_4840760_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000005728 85.0
HKD1_k127_4842476_0 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 354.0
HKD1_k127_4842476_1 nUDIX hydrolase K01515,K03574,K19710 - 2.7.7.53,3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000013 205.0
HKD1_k127_4851393_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.261e-214 677.0
HKD1_k127_4851393_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 353.0
HKD1_k127_4851393_2 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
HKD1_k127_4851393_3 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006725 278.0
HKD1_k127_4851393_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000414 132.0
HKD1_k127_4851393_5 - - - - 0.000000000000000000000000000412 118.0
HKD1_k127_4851393_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000007102 69.0
HKD1_k127_4931518_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000001471 151.0
HKD1_k127_4941303_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 509.0
HKD1_k127_4941303_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
HKD1_k127_4941303_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000001467 65.0
HKD1_k127_4951404_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000009242 143.0
HKD1_k127_4951404_1 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000002619 103.0
HKD1_k127_4951404_2 intracellular chloride channel activity K05027,K05030 - - 0.0003324 53.0
HKD1_k127_4964963_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 574.0
HKD1_k127_4964963_1 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 432.0
HKD1_k127_4964963_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 368.0
HKD1_k127_4964963_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001835 236.0
HKD1_k127_4964963_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000002254 242.0
HKD1_k127_4976023_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 334.0
HKD1_k127_4976023_1 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000005876 132.0
HKD1_k127_4976914_0 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 292.0
HKD1_k127_4976914_1 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000002 203.0
HKD1_k127_4976914_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000007584 184.0
HKD1_k127_4976914_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000006103 175.0
HKD1_k127_498329_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 421.0
HKD1_k127_498329_1 tpr repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002455 273.0
HKD1_k127_498329_2 PFAM Resolvase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
HKD1_k127_498329_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000009419 213.0
HKD1_k127_498329_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000004019 176.0
HKD1_k127_498329_5 PBS lyase - - - 0.00000000000000001326 98.0
HKD1_k127_498329_7 Phage integrase, N-terminal SAM-like domain - - - 0.000000000002951 72.0
HKD1_k127_498329_8 Domain of unknown function (DUF3943) - - - 0.0002654 48.0
HKD1_k127_4983633_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 368.0
HKD1_k127_4983633_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 363.0
HKD1_k127_4983633_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000004706 207.0
HKD1_k127_4983633_3 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000008869 189.0
HKD1_k127_4983633_4 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000079 191.0
HKD1_k127_4983633_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000004003 87.0
HKD1_k127_4983633_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000009005 81.0
HKD1_k127_4991260_0 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 573.0
HKD1_k127_4991260_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 437.0
HKD1_k127_4991260_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 309.0
HKD1_k127_4991260_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001953 233.0
HKD1_k127_4991260_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000001645 132.0
HKD1_k127_4991260_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000002386 57.0
HKD1_k127_4991260_7 Hydrolase K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - 0.0005664 51.0
HKD1_k127_4999999_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000455 267.0
HKD1_k127_4999999_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000007268 249.0
HKD1_k127_5010514_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.524e-210 674.0
HKD1_k127_5010514_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
HKD1_k127_5010514_2 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 336.0
HKD1_k127_5010514_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001648 279.0
HKD1_k127_5010514_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000009065 211.0
HKD1_k127_5010514_5 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000000008153 158.0
HKD1_k127_5010514_6 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000000004851 113.0
HKD1_k127_5010514_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000003651 78.0
HKD1_k127_5013634_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005555 249.0
HKD1_k127_5013634_1 PFAM DinB family - - - 0.000000000000000000000000000000000000000000000000000000003852 204.0
HKD1_k127_5013634_2 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000003161 183.0
HKD1_k127_5013634_3 COG1278 Cold shock proteins K03704 - - 0.0000000000000000000000001923 107.0
HKD1_k127_5013634_4 Diadenylate cyclase - - - 0.00000002905 65.0
HKD1_k127_5027770_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 340.0
HKD1_k127_5027770_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 330.0
HKD1_k127_5027770_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000025 281.0
HKD1_k127_5027770_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000003815 150.0
HKD1_k127_5034649_0 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003871 265.0
HKD1_k127_5034649_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320,K14728 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000002372 254.0
HKD1_k127_5034649_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000004679 228.0
HKD1_k127_5034649_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000004432 197.0
HKD1_k127_5034649_4 Lactonase, 7-bladed beta-propeller K07004 - - 0.00000001621 66.0
HKD1_k127_5084890_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 515.0
HKD1_k127_5084890_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 363.0
HKD1_k127_5084890_2 response regulator receiver K02479,K07692 - - 0.000000000001102 76.0
HKD1_k127_5087091_0 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 526.0
HKD1_k127_5087091_1 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 488.0
HKD1_k127_5087091_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 332.0
HKD1_k127_5087091_3 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
HKD1_k127_5087091_4 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000144 193.0
HKD1_k127_5087091_5 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000001363 130.0
HKD1_k127_5087091_6 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000003059 123.0
HKD1_k127_5101359_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 9.386e-216 679.0
HKD1_k127_5101359_1 Carbon-nitrogen hydrolase K18282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002109 259.0
HKD1_k127_5101359_2 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000001044 234.0
HKD1_k127_5101359_3 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000983 111.0
HKD1_k127_5102596_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001928 276.0
HKD1_k127_5102596_1 Acyl carrier protein phosphodiesterase K08682 - 3.1.4.14 0.000000000000000000000000000000000000000000000000000000001239 207.0
HKD1_k127_5102596_2 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000005835 173.0
HKD1_k127_5102596_3 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.00000000000000000000000000000000000000001197 157.0
HKD1_k127_5137160_0 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 345.0
HKD1_k127_5137160_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 310.0
HKD1_k127_5137160_2 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000009886 143.0
HKD1_k127_5137160_3 - - - - 0.00000000000000008728 84.0
HKD1_k127_5137160_4 - - - - 0.000000000001128 78.0
HKD1_k127_5137160_5 Fimbrial assembly family protein K02461 - - 0.00001458 57.0
HKD1_k127_5137160_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.00003816 53.0
HKD1_k127_515226_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.583e-300 937.0
HKD1_k127_515226_1 GTP-binding protein TypA K06207 - - 2.169e-237 748.0
HKD1_k127_515226_10 Sulfotransferase family - - - 0.00000000006374 66.0
HKD1_k127_515226_11 Hydroxysteroid dehydrogenase-like protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000002124 62.0
HKD1_k127_515226_12 - - - - 0.000003222 49.0
HKD1_k127_515226_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03407,K03642,K06182,K08372,K12065 - 2.7.13.3,5.4.99.21 0.00001987 55.0
HKD1_k127_515226_14 - - - - 0.0006689 46.0
HKD1_k127_515226_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.143e-227 721.0
HKD1_k127_515226_3 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000267 287.0
HKD1_k127_515226_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009754 263.0
HKD1_k127_515226_5 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
HKD1_k127_515226_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000009578 141.0
HKD1_k127_515226_7 - - - - 0.0000000000000000000000003515 106.0
HKD1_k127_515226_8 Sulfotransferase family - - - 0.000000000000004191 76.0
HKD1_k127_515226_9 Sulfotransferase family - - - 0.00000000000008035 75.0
HKD1_k127_5223524_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 541.0
HKD1_k127_5223524_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 437.0
HKD1_k127_5223524_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 387.0
HKD1_k127_5223524_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000114 231.0
HKD1_k127_5223524_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000002203 177.0
HKD1_k127_5223524_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000005549 145.0
HKD1_k127_5223524_6 - - - - 0.00000000000000002244 85.0
HKD1_k127_5223524_7 - - - - 0.00000006013 61.0
HKD1_k127_5248029_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0 1416.0
HKD1_k127_5248029_1 glycogen debranching - - - 5.19e-293 913.0
HKD1_k127_5248029_10 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 326.0
HKD1_k127_5248029_11 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
HKD1_k127_5248029_12 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008824 282.0
HKD1_k127_5248029_13 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001702 235.0
HKD1_k127_5248029_14 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000001858 222.0
HKD1_k127_5248029_15 - - - - 0.00000000000000000000000000000000000000000000000000001366 192.0
HKD1_k127_5248029_16 Haem-degrading - - - 0.00000000000000000000000000000000001697 141.0
HKD1_k127_5248029_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002548 128.0
HKD1_k127_5248029_18 integral membrane protein - - - 0.00000000000000000000000000002184 125.0
HKD1_k127_5248029_19 - - - - 0.000000000476 63.0
HKD1_k127_5248029_2 choline dehydrogenase activity - - - 2.03e-257 802.0
HKD1_k127_5248029_20 Putative zinc-finger - - - 0.00000003653 58.0
HKD1_k127_5248029_21 - - - - 0.0000009344 54.0
HKD1_k127_5248029_3 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 573.0
HKD1_k127_5248029_4 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 584.0
HKD1_k127_5248029_5 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 519.0
HKD1_k127_5248029_6 PFAM RNA polymerase sigma factor 54, interaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 512.0
HKD1_k127_5248029_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
HKD1_k127_5248029_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 383.0
HKD1_k127_5248029_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
HKD1_k127_5253076_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 4.5e-307 957.0
HKD1_k127_5253076_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 593.0
HKD1_k127_5253076_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 437.0
HKD1_k127_5253076_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 382.0
HKD1_k127_5253076_4 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
HKD1_k127_5253076_5 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
HKD1_k127_5253076_6 Tetratricopeptide repeat - - - 0.000000000000000003138 95.0
HKD1_k127_5258665_0 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000007661 115.0
HKD1_k127_5258665_1 - - - - 0.0000000000000000000007113 106.0
HKD1_k127_5280772_0 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
HKD1_k127_5280772_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 291.0
HKD1_k127_5280772_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000004011 160.0
HKD1_k127_5280772_3 Phosphotransferase system mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000001483 52.0
HKD1_k127_5289699_0 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 483.0
HKD1_k127_5289699_1 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 459.0
HKD1_k127_5289699_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 364.0
HKD1_k127_5295232_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 490.0
HKD1_k127_5310857_0 PFAM Carbon starvation protein CstA K06200 - - 3.608e-223 707.0
HKD1_k127_5310857_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001109 203.0
HKD1_k127_5342534_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.832e-218 683.0
HKD1_k127_5342534_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 291.0
HKD1_k127_5342534_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 266.0
HKD1_k127_5342534_3 CoA-binding protein K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000003498 220.0
HKD1_k127_5342534_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000005515 201.0
HKD1_k127_5342534_5 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000002003 201.0
HKD1_k127_5366565_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
HKD1_k127_5366565_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HKD1_k127_5366565_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000002652 199.0
HKD1_k127_5366565_3 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000001394 165.0
HKD1_k127_5366565_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000006367 146.0
HKD1_k127_5366565_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.00000000000000000007669 103.0
HKD1_k127_5370502_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
HKD1_k127_5370502_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 265.0
HKD1_k127_5370502_2 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000003339 209.0
HKD1_k127_5370502_3 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000005606 150.0
HKD1_k127_5381868_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 561.0
HKD1_k127_5381868_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 329.0
HKD1_k127_5381868_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 324.0
HKD1_k127_5382876_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.835e-230 727.0
HKD1_k127_5382876_1 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 326.0
HKD1_k127_5382876_2 glycosyl transferase family - - - 0.000000000000000000000000000000000000000000000000001372 202.0
HKD1_k127_5382876_3 Domain of unknown function (DUF4340) - - - 0.0002743 47.0
HKD1_k127_5394331_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.659e-266 833.0
HKD1_k127_5394331_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 493.0
HKD1_k127_5394331_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 297.0
HKD1_k127_5394331_3 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000007851 226.0
HKD1_k127_5394331_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000002527 133.0
HKD1_k127_5436078_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 478.0
HKD1_k127_5436078_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.00000000000000000000000000000000000000000003547 167.0
HKD1_k127_5436078_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000007057 132.0
HKD1_k127_5493156_0 to orf3 of fosmid clone 4B7mr3 - - - 3.393e-236 734.0
HKD1_k127_5493156_1 Protein of unknown function (DUF354) K09726 - - 1.356e-211 660.0
HKD1_k127_5493156_2 - - - - 0.0000000001863 61.0
HKD1_k127_5493156_3 - - - - 0.00005796 52.0
HKD1_k127_5510407_0 Nacht domain - - - 0.0000000000000000000000157 115.0
HKD1_k127_5510407_1 Histidine kinase - - - 0.00003487 47.0
HKD1_k127_5510407_2 - - - - 0.00003666 56.0
HKD1_k127_5519275_0 Sigma-54 interaction domain K11384 - - 7.861e-196 621.0
HKD1_k127_5519275_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 303.0
HKD1_k127_5519275_2 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000576 109.0
HKD1_k127_5530598_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.559e-213 674.0
HKD1_k127_5530598_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 391.0
HKD1_k127_5530598_2 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
HKD1_k127_5530598_3 - - - - 0.000000000000000000000000000000000000000000005162 168.0
HKD1_k127_5530598_4 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.00000000000000000000000000000000000000007724 156.0
HKD1_k127_5530598_5 - - - - 0.00000000000000000000000000000000000001498 150.0
HKD1_k127_556533_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 503.0
HKD1_k127_556533_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 304.0
HKD1_k127_556533_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 264.0
HKD1_k127_556533_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000002224 182.0
HKD1_k127_556533_4 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000003654 188.0
HKD1_k127_556533_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001655 164.0
HKD1_k127_556533_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001736 165.0
HKD1_k127_556533_7 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000004359 141.0
HKD1_k127_556533_8 - - - - 0.00000000000000000000000004027 111.0
HKD1_k127_5573134_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.599e-267 834.0
HKD1_k127_5573134_1 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 577.0
HKD1_k127_5573134_2 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 467.0
HKD1_k127_5573134_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 303.0
HKD1_k127_5573134_4 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000001657 100.0
HKD1_k127_5573134_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000001319 53.0
HKD1_k127_5573486_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.387e-199 637.0
HKD1_k127_5573486_1 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000346 255.0
HKD1_k127_5573486_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000005467 139.0
HKD1_k127_5573486_3 CAAX protease self-immunity K07052 - - 0.0000001108 61.0
HKD1_k127_560874_0 Cytochrome c - - - 0.00000000000000000000000000000000000000008066 156.0
HKD1_k127_5683112_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 323.0
HKD1_k127_5683112_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000006163 205.0
HKD1_k127_5683112_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000147 165.0
HKD1_k127_5683112_3 Lysin motif - - - 0.00000000000000000000000000000000000000211 155.0
HKD1_k127_5683112_4 Pfam:DUF385 - - - 0.0000000000000000000000000000000000006601 144.0
HKD1_k127_5683112_5 TfoX N-terminal domain - - - 0.0000000000000000000000000000003097 125.0
HKD1_k127_5683112_6 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000003938 124.0
HKD1_k127_5683112_7 energy transducer activity K03832 - - 0.0000000000000000000000001657 115.0
HKD1_k127_5683112_8 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000001333 105.0
HKD1_k127_5683112_9 Diacylglycerol kinase catalytic domain - - - 0.0003393 52.0
HKD1_k127_5702908_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 503.0
HKD1_k127_5702908_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000003371 255.0
HKD1_k127_5702908_2 Peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.00000006672 63.0
HKD1_k127_5702908_3 PFAM ASPIC UnbV domain protein - - - 0.0002477 48.0
HKD1_k127_5709302_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 391.0
HKD1_k127_5709302_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000009474 156.0
HKD1_k127_5709302_2 - - - - 0.000000000000000000000005223 105.0
HKD1_k127_5771838_0 iron ion homeostasis K02015 - - 0.00000000000000000000000001345 110.0
HKD1_k127_578060_0 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 420.0
HKD1_k127_578060_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000002702 130.0
HKD1_k127_5784990_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 463.0
HKD1_k127_5784990_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 329.0
HKD1_k127_5784990_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
HKD1_k127_5784990_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
HKD1_k127_5784990_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000004553 237.0
HKD1_k127_5784990_5 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000006932 243.0
HKD1_k127_5784990_6 dehydratase - - - 0.00000000000000000000000000000000000003178 154.0
HKD1_k127_5784990_7 Extracellular nuclease - - - 0.00000000000000000000000000001152 127.0
HKD1_k127_5787933_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 565.0
HKD1_k127_5787933_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003466 275.0
HKD1_k127_5787933_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000004502 153.0
HKD1_k127_5787933_3 HEAT repeats - - - 0.00001612 52.0
HKD1_k127_5790840_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1306.0
HKD1_k127_5790840_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 546.0
HKD1_k127_5790840_2 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 321.0
HKD1_k127_5790840_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 306.0
HKD1_k127_5790840_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000004823 172.0
HKD1_k127_5790840_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000007021 162.0
HKD1_k127_5790840_6 Thioredoxin-like K02199,K03671 - - 0.0000000000000000000000000000000000362 141.0
HKD1_k127_5790840_7 subunit of a heme lyase K02200 - - 0.000000000000000000000001715 109.0
HKD1_k127_5790840_8 monooxygenase activity - - - 0.000000000000000000000007798 107.0
HKD1_k127_581885_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 402.0
HKD1_k127_581885_1 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 336.0
HKD1_k127_581885_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002153 266.0
HKD1_k127_581885_3 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002854 244.0
HKD1_k127_581885_4 phosphoesterase, PA-phosphatase related - - - 0.00000000000000001185 91.0
HKD1_k127_5842683_0 - - - - 1.741e-223 693.0
HKD1_k127_5842683_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000005265 173.0
HKD1_k127_5842683_2 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000002128 151.0
HKD1_k127_5885873_0 Belongs to the peptidase S16 family - - - 5.317e-250 795.0
HKD1_k127_5885873_1 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 273.0
HKD1_k127_5885873_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
HKD1_k127_5885873_3 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000000000000000001362 188.0
HKD1_k127_5885873_4 Rdx family K07401 - - 0.000000000000000000000000000000000001838 139.0
HKD1_k127_5885873_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000004699 143.0
HKD1_k127_5885873_6 membrane - - - 0.0000000000000000000000000000001048 128.0
HKD1_k127_5885873_7 Protein tyrosine kinase - - - 0.00000000000000000000001388 105.0
HKD1_k127_5885873_8 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000008913 72.0
HKD1_k127_5886090_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 479.0
HKD1_k127_5886090_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 443.0
HKD1_k127_5886090_10 wide pore channel activity K07267 - - 0.000000000000000000000000000000003505 140.0
HKD1_k127_5886090_11 Cupin-like domain - - - 0.00000000000000000000001036 111.0
HKD1_k127_5886090_12 - - - - 0.0000000000000000000005784 103.0
HKD1_k127_5886090_13 Uncharacterised nucleotidyltransferase - - - 0.00000000002315 75.0
HKD1_k127_5886090_14 Ion channel K10716 - - 0.000001113 59.0
HKD1_k127_5886090_15 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000005952 54.0
HKD1_k127_5886090_16 competence protein F - - - 0.0008146 43.0
HKD1_k127_5886090_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 443.0
HKD1_k127_5886090_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 420.0
HKD1_k127_5886090_4 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 387.0
HKD1_k127_5886090_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 310.0
HKD1_k127_5886090_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 296.0
HKD1_k127_5886090_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007742 255.0
HKD1_k127_5886090_8 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008219 233.0
HKD1_k127_5886090_9 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000001356 186.0
HKD1_k127_5891837_0 Glycogen debranching enzyme - - - 0.0 1255.0
HKD1_k127_5891837_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.45e-322 1007.0
HKD1_k127_5891837_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 336.0
HKD1_k127_5891837_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000066 287.0
HKD1_k127_5891837_4 peptidase activity - - - 0.00000000000000000000000000000000000000307 159.0
HKD1_k127_5891837_5 - - - - 0.0000000000000000000000002152 110.0
HKD1_k127_5891837_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000004462 90.0
HKD1_k127_5895375_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 306.0
HKD1_k127_5895375_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002603 278.0
HKD1_k127_5895375_2 YCII-related domain - - - 0.00000000000000000000005921 101.0
HKD1_k127_5910078_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 356.0
HKD1_k127_5910078_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 348.0
HKD1_k127_5910078_2 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000002817 119.0
HKD1_k127_5910078_3 - - - - 0.000000000000003214 79.0
HKD1_k127_5910078_4 Belongs to the Dps family K04047 - - 0.000000000000007841 75.0
HKD1_k127_5948370_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1480.0
HKD1_k127_5948370_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007935 273.0
HKD1_k127_5948370_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0008703 43.0
HKD1_k127_5948370_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000005396 173.0
HKD1_k127_5948370_3 - - - - 0.00000000000000000000000000000000000000000003756 170.0
HKD1_k127_5948370_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000006355 132.0
HKD1_k127_5948370_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002317 133.0
HKD1_k127_5948370_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03591,K03749 - - 0.00000000006352 68.0
HKD1_k127_5948370_7 Transcriptional regulatory protein, C terminal - - - 0.0000005218 58.0
HKD1_k127_5948370_8 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.000003416 57.0
HKD1_k127_5948370_9 general secretion pathway protein K02650 - - 0.000004075 57.0
HKD1_k127_5961404_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.506e-267 848.0
HKD1_k127_5961404_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 392.0
HKD1_k127_5961404_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000001335 228.0
HKD1_k127_5961404_3 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000001078 164.0
HKD1_k127_5961404_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000003294 93.0
HKD1_k127_597303_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000039 276.0
HKD1_k127_597303_1 copper resistance K07245,K14166 - - 0.000000000000000000000000000000000000000000003053 176.0
HKD1_k127_597303_2 response to copper ion K07156,K14166 - - 0.00000000000000000000000000000009792 128.0
HKD1_k127_597303_3 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000001825 120.0
HKD1_k127_6044888_0 glycosyl transferase family - - - 0.0000000000009367 76.0
HKD1_k127_6044888_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0002017 51.0
HKD1_k127_6065618_0 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
HKD1_k127_6065618_1 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000008014 151.0
HKD1_k127_6065618_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0000000000000000000000000006682 116.0
HKD1_k127_6065618_3 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.000000000000003558 78.0
HKD1_k127_6077989_0 O-methyltransferase - - - 0.00000000000000000000000000000000000000003082 164.0
HKD1_k127_6077989_1 Ester cyclase - - - 0.000000000000000000000000000000000000002466 150.0
HKD1_k127_6077989_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000005173 104.0
HKD1_k127_6077989_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000006145 101.0
HKD1_k127_6077989_4 RDD family - - - 0.0000000000000000006313 94.0
HKD1_k127_6077989_5 - - - - 0.00000000746 66.0
HKD1_k127_6077989_6 antibiotic catabolic process - - - 0.00001053 49.0
HKD1_k127_6090525_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.063e-295 919.0
HKD1_k127_6090525_1 peptidase U62 modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 517.0
HKD1_k127_6090525_10 Protein of unknown function (DUF1232) - - - 0.000000000000000000001752 99.0
HKD1_k127_6090525_11 Major facilitator superfamily K08170 - - 0.00000000000000006226 87.0
HKD1_k127_6090525_12 Major Facilitator Superfamily - - - 0.0000000001276 67.0
HKD1_k127_6090525_13 Major Facilitator Superfamily - - - 0.00000003031 56.0
HKD1_k127_6090525_14 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000007087 61.0
HKD1_k127_6090525_15 phosphate-selective porin O and P - - - 0.0000007855 53.0
HKD1_k127_6090525_2 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 295.0
HKD1_k127_6090525_3 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 290.0
HKD1_k127_6090525_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
HKD1_k127_6090525_5 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000004246 191.0
HKD1_k127_6090525_6 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000001029 188.0
HKD1_k127_6090525_7 major facilitator superfamily K08170 - - 0.0000000000000000000000000003639 120.0
HKD1_k127_6090525_8 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000007778 111.0
HKD1_k127_6090525_9 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003685 106.0
HKD1_k127_6117477_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.269e-277 877.0
HKD1_k127_6117477_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 419.0
HKD1_k127_6117477_2 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 340.0
HKD1_k127_6117477_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000001714 117.0
HKD1_k127_6117477_4 signal-transduction protein containing cAMP-binding and CBS domains K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000000000004889 98.0
HKD1_k127_6117477_5 Cytochrome c - - - 0.0000001316 53.0
HKD1_k127_6117477_6 AMP binding - - - 0.0000897 53.0
HKD1_k127_6186096_0 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 545.0
HKD1_k127_6186096_1 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000008345 222.0
HKD1_k127_6186096_2 Redoxin - - - 0.000000000000000000000000000000000000002311 151.0
HKD1_k127_6186096_4 Redoxin - - - 0.00000000004024 64.0
HKD1_k127_6228413_0 TIGRFAM Ammonium transporter K03320 - - 1.289e-199 632.0
HKD1_k127_6228413_1 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000001333 230.0
HKD1_k127_6228413_2 MarR family - - - 0.0000000000000000000000000000000003259 138.0
HKD1_k127_6228413_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000002707 123.0
HKD1_k127_6228413_4 Evidence 4 Homologs of previously reported genes of K15977 - - 0.0000000000000000000000007891 109.0
HKD1_k127_6228413_5 ISXO2-like transposase domain K07488 - - 0.00000000000000000003622 99.0
HKD1_k127_6228413_6 Beta-lactamase - - - 0.0000000000003333 74.0
HKD1_k127_6228413_7 Beta-lactamase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000007842 62.0
HKD1_k127_6229437_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 534.0
HKD1_k127_6229437_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 411.0
HKD1_k127_6229437_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 323.0
HKD1_k127_6229437_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000009598 257.0
HKD1_k127_6229437_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000006802 147.0
HKD1_k127_6229437_5 Lytic transglycolase K20628 - - 0.000000003998 60.0
HKD1_k127_6235603_0 Protein of unknown function (DUF3141) - - - 1.74e-203 646.0
HKD1_k127_6246463_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1140.0
HKD1_k127_6246463_1 aminopeptidase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 405.0
HKD1_k127_6246463_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
HKD1_k127_6246463_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000002561 188.0
HKD1_k127_6246463_4 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000005908 182.0
HKD1_k127_6246463_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000004187 177.0
HKD1_k127_6246463_6 YGGT family K02221 - - 0.000000000000000000000000000001561 123.0
HKD1_k127_6246463_7 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000144 117.0
HKD1_k127_6246463_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000174 64.0
HKD1_k127_6246463_9 Belongs to the UPF0235 family K09131 - - 0.00000001415 57.0
HKD1_k127_6252818_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 341.0
HKD1_k127_6252818_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 321.0
HKD1_k127_6252818_2 ChaB K06197 - - 0.00000000000000000000000001993 109.0
HKD1_k127_6252818_3 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000003566 102.0
HKD1_k127_6252818_4 UPF0391 membrane protein - - - 0.000000000000003926 77.0
HKD1_k127_6252818_5 Protein of unknown function (DUF3309) - - - 0.00000000000009496 72.0
HKD1_k127_6252818_6 Transcriptional regulator - - - 0.00001003 50.0
HKD1_k127_6252818_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.0001792 48.0
HKD1_k127_6252818_8 response regulator receiver K02481,K07714,K10943 - - 0.0008481 45.0
HKD1_k127_6303226_0 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000004597 105.0
HKD1_k127_6303226_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000005963 58.0
HKD1_k127_6303765_0 PHB de-polymerase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 422.0
HKD1_k127_6303765_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 317.0
HKD1_k127_6303765_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000428 133.0
HKD1_k127_6315992_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 292.0
HKD1_k127_6315992_1 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000007551 247.0
HKD1_k127_6315992_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000384 246.0
HKD1_k127_6315992_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000002332 238.0
HKD1_k127_6315992_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000005188 234.0
HKD1_k127_6315992_5 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000003823 198.0
HKD1_k127_6315992_6 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000005084 172.0
HKD1_k127_6315992_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000009207 107.0
HKD1_k127_6315992_8 Glycosyl transferases group 1 - - - 0.00000000000000000002326 106.0
HKD1_k127_6315992_9 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000009938 63.0
HKD1_k127_6330232_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 338.0
HKD1_k127_6330232_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000004416 225.0
HKD1_k127_6330232_2 VWA domain containing CoxE-like protein K09989 - - 0.000000000000000000000000004501 111.0
HKD1_k127_6330232_3 protein-disulfide reductase activity - - - 0.000000000007691 73.0
HKD1_k127_6341908_0 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000009441 152.0
HKD1_k127_6341908_1 diguanylate cyclase - - - 0.0000000000000000000000000000000002422 141.0
HKD1_k127_6341908_2 Diguanylate cyclase - - - 0.00002443 47.0
HKD1_k127_6342474_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 571.0
HKD1_k127_6342474_1 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 422.0
HKD1_k127_6342474_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007475 265.0
HKD1_k127_6345722_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 389.0
HKD1_k127_6345722_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002382 254.0
HKD1_k127_6345722_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000004676 193.0
HKD1_k127_6346500_0 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 519.0
HKD1_k127_6346500_1 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 467.0
HKD1_k127_6346500_2 - - - - 0.000000000000000000000000000000000000000000000002286 183.0
HKD1_k127_6346500_3 Flagellar Motor Protein K02557 - - 0.0000000000000000000000000000000000000000001873 165.0
HKD1_k127_6346500_4 lipolytic protein G-D-S-L family - - - 0.0000000000001418 83.0
HKD1_k127_6350323_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000001595 165.0
HKD1_k127_6350323_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000004372 147.0
HKD1_k127_6350323_2 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.00000000000000000000000001647 112.0
HKD1_k127_6350323_3 Tetratricopeptide repeat - - - 0.0000000000000000000000001378 109.0
HKD1_k127_6352744_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 493.0
HKD1_k127_6352744_1 to be involved in C-type cytochrome biogenesis K04084 - 1.8.1.8 0.000000000001275 75.0
HKD1_k127_6387762_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 4.684e-231 739.0
HKD1_k127_6387762_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 525.0
HKD1_k127_6387762_2 RNB K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 313.0
HKD1_k127_6387762_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000003185 171.0
HKD1_k127_6387762_4 membrane-associated Zn-dependent proteases 1 - - - 0.00000000000000000000000000004063 119.0
HKD1_k127_6387762_5 Family of unknown function (DUF5329) - - - 0.0000000000000000000000000008334 116.0
HKD1_k127_6435797_0 oligoendopeptidase F K08602 - - 3.076e-200 640.0
HKD1_k127_6435797_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 522.0
HKD1_k127_6435797_10 - - - - 0.000002905 53.0
HKD1_k127_6435797_11 - - - - 0.00003134 48.0
HKD1_k127_6435797_12 EamA-like transporter family - - - 0.0009684 46.0
HKD1_k127_6435797_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 456.0
HKD1_k127_6435797_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000004612 234.0
HKD1_k127_6435797_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000007743 194.0
HKD1_k127_6435797_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.0000000000000000000000000000000000000000000001679 175.0
HKD1_k127_6435797_6 GatB Yqey domain protein K09117 - - 0.00000000000000000000000000000000002491 140.0
HKD1_k127_6435797_7 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000001068 129.0
HKD1_k127_6435797_8 C4-type zinc ribbon domain K07164 - - 0.000000000001037 70.0
HKD1_k127_6435797_9 Bacterial type II/III secretion system short domain K02453 - - 0.0000008623 56.0
HKD1_k127_6464594_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 6.857e-220 711.0
HKD1_k127_6464594_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.575e-218 692.0
HKD1_k127_6464594_10 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000001392 165.0
HKD1_k127_6464594_11 adenosyltransferase K00798 - 2.5.1.17 0.0000000005569 61.0
HKD1_k127_6464594_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 597.0
HKD1_k127_6464594_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 464.0
HKD1_k127_6464594_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HKD1_k127_6464594_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 423.0
HKD1_k127_6464594_6 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
HKD1_k127_6464594_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 313.0
HKD1_k127_6464594_8 Methyltransferase domain K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000727 213.0
HKD1_k127_6464594_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000002112 176.0
HKD1_k127_6479481_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 357.0
HKD1_k127_6479481_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000002197 193.0
HKD1_k127_6479481_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000002832 120.0
HKD1_k127_6479481_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000001822 79.0
HKD1_k127_6479481_4 zinc-ribbon domain - - - 0.00000397 49.0
HKD1_k127_6500028_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K01286,K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 561.0
HKD1_k127_6500028_1 Alpha/beta hydrolase family K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 404.0
HKD1_k127_6500028_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000002068 202.0
HKD1_k127_6500028_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000004234 189.0
HKD1_k127_6500028_4 Aromatic acid exporter family member 1 - - - 0.0000000000000000000000000000002489 129.0
HKD1_k127_6500028_5 - - - - 0.00000000000000000006071 94.0
HKD1_k127_6500028_6 PFAM Collagen triple helix repeat (20 copies) - - - 0.00000000000298 78.0
HKD1_k127_6500028_7 amine dehydrogenase activity - - - 0.000001328 51.0
HKD1_k127_6501758_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 481.0
HKD1_k127_6501758_1 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 355.0
HKD1_k127_6501758_2 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320,K14728 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000172 237.0
HKD1_k127_6501758_3 thioesterase - - - 0.00000000000000000000000000000000000000000000004076 174.0
HKD1_k127_6501758_4 - - - - 0.000000000000007906 83.0
HKD1_k127_6501758_5 PurA ssDNA and RNA-binding protein K21772 GO:0000003,GO:0000075,GO:0000228,GO:0000278,GO:0000781,GO:0000784,GO:0000900,GO:0000981,GO:0001067,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003691,GO:0003697,GO:0003700,GO:0003705,GO:0003723,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005662,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006355,GO:0006357,GO:0006417,GO:0006725,GO:0006807,GO:0006915,GO:0006996,GO:0007049,GO:0007093,GO:0007275,GO:0007276,GO:0007281,GO:0007346,GO:0007399,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0012501,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0030371,GO:0030425,GO:0030894,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031935,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032392,GO:0032422,GO:0032501,GO:0032502,GO:0032504,GO:0032508,GO:0032991,GO:0032993,GO:0033043,GO:0033044,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0035770,GO:0036464,GO:0036477,GO:0040012,GO:0042127,GO:0042162,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043601,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044463,GO:0044464,GO:0044703,GO:0045182,GO:0045495,GO:0045786,GO:0045892,GO:0045930,GO:0045934,GO:0046332,GO:0046483,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051276,GO:0051704,GO:0051726,GO:0060255,GO:0060293,GO:0060968,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097447,GO:0097458,GO:0098687,GO:0120025,GO:0120038,GO:0140110,GO:1901360,GO:1901363,GO:1901576,GO:1902275,GO:1902679,GO:1903047,GO:1903506,GO:1903507,GO:1990124,GO:1990837,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000002589 62.0
HKD1_k127_6501758_6 Methylamine utilisation protein MauE - - - 0.00000001012 63.0
HKD1_k127_6504345_0 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000001279 186.0
HKD1_k127_6504345_1 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000003059 144.0
HKD1_k127_6504345_3 general secretion pathway protein K02246,K02247,K02456,K02457,K02458,K10924 - - 0.0000005755 58.0
HKD1_k127_6504345_4 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000003319 56.0
HKD1_k127_651626_0 PAS fold - - - 0.0 1268.0
HKD1_k127_651626_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 6.36e-240 743.0
HKD1_k127_651626_2 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 478.0
HKD1_k127_6527539_0 DEAD DEAH box helicase K03724 - - 0.0 1746.0
HKD1_k127_6527539_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.123e-278 870.0
HKD1_k127_6527539_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000007288 116.0
HKD1_k127_6527539_11 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000001759 87.0
HKD1_k127_6527539_12 AmiS/UreI family transporter K22112 - - 0.00000000000008596 78.0
HKD1_k127_6527539_13 Acetoacetate decarboxylase (ADC) - - - 0.00000002739 65.0
HKD1_k127_6527539_14 Acetoacetate decarboxylase (ADC) - - - 0.000198 53.0
HKD1_k127_6527539_2 K+ potassium transporter K03549 - - 2.568e-208 666.0
HKD1_k127_6527539_3 Bacterial protein of unknown function (DUF853) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 371.0
HKD1_k127_6527539_4 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 323.0
HKD1_k127_6527539_5 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
HKD1_k127_6527539_6 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
HKD1_k127_6527539_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000007226 214.0
HKD1_k127_6527539_8 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000009659 159.0
HKD1_k127_6527539_9 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000008475 144.0
HKD1_k127_6552167_0 4Fe-4S dicluster domain K00184 - - 1.378e-229 743.0
HKD1_k127_6552167_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000009043 207.0
HKD1_k127_6552167_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000005848 148.0
HKD1_k127_6552167_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000002402 145.0
HKD1_k127_6552167_4 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000001691 123.0
HKD1_k127_6552167_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0003245 43.0
HKD1_k127_6554204_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 598.0
HKD1_k127_6554204_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
HKD1_k127_6554204_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 306.0
HKD1_k127_6554204_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003862 282.0
HKD1_k127_6554204_4 TRAM domain K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 271.0
HKD1_k127_6554204_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000007759 187.0
HKD1_k127_6554204_6 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000001634 155.0
HKD1_k127_6561295_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.174e-237 739.0
HKD1_k127_6561295_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.396e-231 724.0
HKD1_k127_6561295_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000299 202.0
HKD1_k127_6561295_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000005335 161.0
HKD1_k127_6561295_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000004988 144.0
HKD1_k127_6561295_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000001141 121.0
HKD1_k127_6561295_14 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000003787 112.0
HKD1_k127_6561295_15 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000001509 107.0
HKD1_k127_6561295_16 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000188 110.0
HKD1_k127_6561295_17 - - - - 0.00000000000000000000002718 113.0
HKD1_k127_6561295_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000157 85.0
HKD1_k127_6561295_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 544.0
HKD1_k127_6561295_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 519.0
HKD1_k127_6561295_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 407.0
HKD1_k127_6561295_5 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 392.0
HKD1_k127_6561295_6 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
HKD1_k127_6561295_7 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 298.0
HKD1_k127_6561295_8 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
HKD1_k127_6561295_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
HKD1_k127_6567477_0 serine-type peptidase activity K08676 - - 0.0 1095.0
HKD1_k127_6574864_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 362.0
HKD1_k127_6574864_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 357.0
HKD1_k127_6574864_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 298.0
HKD1_k127_6574864_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000449 117.0
HKD1_k127_6574864_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000005815 116.0
HKD1_k127_6574864_5 GIY-YIG type nucleases (URI domain) K07461 - - 0.000000000000162 71.0
HKD1_k127_6574864_6 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000318 58.0
HKD1_k127_6574864_7 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000006236 68.0
HKD1_k127_6574864_8 GIY-YIG catalytic domain K07461 - - 0.000002178 49.0
HKD1_k127_660362_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004588 274.0
HKD1_k127_660362_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000002473 206.0
HKD1_k127_660362_2 COG2801 Transposase and inactivated derivatives - - - 0.0000000114 57.0
HKD1_k127_660362_3 Belongs to the 'phage' integrase family - - - 0.0000001061 58.0
HKD1_k127_6643511_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000003089 177.0
HKD1_k127_6643511_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000008467 121.0
HKD1_k127_6663070_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 460.0
HKD1_k127_6663070_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
HKD1_k127_6663070_2 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 313.0
HKD1_k127_6663070_3 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004042 252.0
HKD1_k127_6663070_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000005785 183.0
HKD1_k127_6663070_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000001576 166.0
HKD1_k127_6663070_6 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000002826 157.0
HKD1_k127_6689719_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 516.0
HKD1_k127_6689719_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 415.0
HKD1_k127_6689719_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000224 138.0
HKD1_k127_6689719_11 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000001864 104.0
HKD1_k127_6689719_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 406.0
HKD1_k127_6689719_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 291.0
HKD1_k127_6689719_4 Anthranilate synthase component I, N terminal region K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000004653 238.0
HKD1_k127_6689719_5 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000001046 190.0
HKD1_k127_6689719_6 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000002086 190.0
HKD1_k127_6689719_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000003215 150.0
HKD1_k127_6689719_8 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000103 153.0
HKD1_k127_6689719_9 Cation efflux family - - - 0.00000000000000000000000000000000001638 139.0
HKD1_k127_6732375_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
HKD1_k127_6732375_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 301.0
HKD1_k127_6732375_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000003028 205.0
HKD1_k127_6732375_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000002527 179.0
HKD1_k127_6732375_4 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000000000000009968 108.0
HKD1_k127_6732375_5 response to hydrogen peroxide K08985 - - 0.0000000000000001651 82.0
HKD1_k127_6732375_6 - - - - 0.00000000001872 67.0
HKD1_k127_6732375_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000004035 64.0
HKD1_k127_6732375_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000282 70.0
HKD1_k127_6732375_9 Lysin motif K06194 - - 0.000000006469 69.0
HKD1_k127_6789292_0 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 413.0
HKD1_k127_6789292_1 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 377.0
HKD1_k127_6789292_2 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 373.0
HKD1_k127_6789292_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
HKD1_k127_6789292_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HKD1_k127_6789292_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000002846 140.0
HKD1_k127_6789292_6 Metal-sensitive transcriptional repressor - - - 0.000000000000000000000001384 105.0
HKD1_k127_6789292_7 Tetratricopeptide TPR_2 - - - 0.0000000000000000002781 98.0
HKD1_k127_6789682_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 459.0
HKD1_k127_6789682_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000418 231.0
HKD1_k127_6789682_2 O-Antigen ligase K02847 - - 0.000000000000000005702 93.0
HKD1_k127_6789682_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000007053 64.0
HKD1_k127_6813815_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 475.0
HKD1_k127_6813815_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 292.0
HKD1_k127_6813815_2 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006828 251.0
HKD1_k127_6813815_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000005974 185.0
HKD1_k127_6813815_4 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000004198 124.0
HKD1_k127_6824270_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 398.0
HKD1_k127_6824270_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 358.0
HKD1_k127_6824270_2 PFAM Alcohol dehydrogenase, zinc-binding K18369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001265 288.0
HKD1_k127_6824270_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000003344 204.0
HKD1_k127_6824270_4 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000002595 140.0
HKD1_k127_6824270_5 - - - - 0.0006388 50.0
HKD1_k127_6831543_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 604.0
HKD1_k127_6831543_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 525.0
HKD1_k127_6831543_10 Jag_N K06346 - - 0.000000000003747 75.0
HKD1_k127_6831543_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 364.0
HKD1_k127_6831543_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 297.0
HKD1_k127_6831543_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 300.0
HKD1_k127_6831543_5 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001238 273.0
HKD1_k127_6831543_6 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000007658 267.0
HKD1_k127_6831543_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000001816 238.0
HKD1_k127_6831543_8 MafB19-like deaminase K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000003577 174.0
HKD1_k127_6831543_9 Transcription factor zinc-finger K09981 - - 0.0000000000000001071 84.0
HKD1_k127_6864917_0 Large extracellular alpha-helical protein - - - 4.448e-256 814.0
HKD1_k127_6864917_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 356.0
HKD1_k127_6864917_2 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000001067 240.0
HKD1_k127_6864917_3 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000832 224.0
HKD1_k127_6864917_4 Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus K07261 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034645,GO:0042221,GO:0042493,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0050896,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000003769 218.0
HKD1_k127_6864917_5 - - - - 0.0000000000000000000000000000000000000000005105 163.0
HKD1_k127_6864917_6 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000003495 139.0
HKD1_k127_6864917_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000001538 124.0
HKD1_k127_6864917_8 pyrroloquinoline quinone binding - - - 0.0000000000000000192 89.0
HKD1_k127_6864917_9 Psort location CytoplasmicMembrane, score - - - 0.0000004439 56.0
HKD1_k127_6903545_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 593.0
HKD1_k127_6903545_1 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002481 282.0
HKD1_k127_6903545_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000001461 191.0
HKD1_k127_6903545_3 PFAM Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000002151 166.0
HKD1_k127_6903545_4 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000002385 128.0
HKD1_k127_6914690_0 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 481.0
HKD1_k127_6914690_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000001717 149.0
HKD1_k127_6914690_2 PFAM Cobalt transport protein K02008 - - 0.0000000000000000000000000000000008698 141.0
HKD1_k127_6914690_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000666 126.0
HKD1_k127_6914690_4 Belongs to the Fur family K03711 - - 0.000000000000000000000176 103.0
HKD1_k127_6935141_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 533.0
HKD1_k127_6935141_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 315.0
HKD1_k127_6935141_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 313.0
HKD1_k127_6935141_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001502 243.0
HKD1_k127_6935141_4 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
HKD1_k127_6935141_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000004776 104.0
HKD1_k127_6935141_6 PFAM AsmA family K07289 - - 0.00003567 58.0
HKD1_k127_6935141_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0001034 49.0
HKD1_k127_6955532_0 PFAM glycosyl transferase family 51 K05367 - 2.4.1.129 5.897e-213 681.0
HKD1_k127_6955532_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 488.0
HKD1_k127_6955532_2 PFAM glycosyl transferase family 51 K05367 - 2.4.1.129 0.000000000000007397 77.0
HKD1_k127_6955532_3 Cytochrome c mono- and diheme variants - - - 0.00000000007519 67.0
HKD1_k127_697039_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.229e-211 664.0
HKD1_k127_697039_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004294 295.0
HKD1_k127_697039_2 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005788 278.0
HKD1_k127_697039_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000004203 113.0
HKD1_k127_697039_4 Protein of unknown function (DUF2905) - - - 0.0000000000000000001545 90.0
HKD1_k127_697039_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000002729 94.0
HKD1_k127_7032424_0 Pfam Sulfatase K01137 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 512.0
HKD1_k127_7032424_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 410.0
HKD1_k127_7032424_2 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
HKD1_k127_7044107_0 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 357.0
HKD1_k127_7044107_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000005808 196.0
HKD1_k127_7044107_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000204 109.0
HKD1_k127_7073322_0 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
HKD1_k127_7073322_1 ABC transporter, transmembrane region K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 274.0
HKD1_k127_7073322_2 GHMP kinases C terminal K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000019 257.0
HKD1_k127_7073322_3 MobA-like NTP transferase domain K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000001483 174.0
HKD1_k127_7081461_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 526.0
HKD1_k127_7081461_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 388.0
HKD1_k127_7081461_2 - - - - 0.00000006636 55.0
HKD1_k127_7088472_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000004542 183.0
HKD1_k127_7102044_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1055.0
HKD1_k127_7102044_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 7.886e-214 671.0
HKD1_k127_7102044_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 421.0
HKD1_k127_7102044_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000003904 252.0
HKD1_k127_7102044_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000004206 226.0
HKD1_k127_7102044_5 domain protein - - - 0.000000000000000000000000000000000000000000000000000001403 199.0
HKD1_k127_7102044_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000002484 174.0
HKD1_k127_7102044_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000003059 127.0
HKD1_k127_7102044_8 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000001655 111.0
HKD1_k127_7102044_9 Tetratricopeptide repeat K01768 - 4.6.1.1 0.00000000000007366 85.0
HKD1_k127_7119180_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003263 250.0
HKD1_k127_7119180_1 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000002016 138.0
HKD1_k127_7175295_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 494.0
HKD1_k127_7175295_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 368.0
HKD1_k127_7175295_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 341.0
HKD1_k127_7175295_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 324.0
HKD1_k127_7175295_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001042 278.0
HKD1_k127_7175295_5 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000002317 221.0
HKD1_k127_7178848_0 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 601.0
HKD1_k127_7178848_1 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 290.0
HKD1_k127_7178848_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
HKD1_k127_7178848_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000003832 244.0
HKD1_k127_7178848_4 Domains LysM, LysM, NLPC_P60 K19223 - - 0.00000000000000000000000000004453 119.0
HKD1_k127_7178848_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000004148 57.0
HKD1_k127_7199880_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000002259 174.0
HKD1_k127_7199880_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000001988 108.0
HKD1_k127_7199880_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000002036 101.0
HKD1_k127_7229480_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000005478 216.0
HKD1_k127_7229480_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000005746 220.0
HKD1_k127_7229480_2 Pfam:DUF2029 K00728 - 2.4.1.109 0.00000000000000000000000000000002762 140.0
HKD1_k127_7240442_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1437.0
HKD1_k127_724828_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000269 255.0
HKD1_k127_724828_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000354 244.0
HKD1_k127_724828_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000004959 184.0
HKD1_k127_724828_3 - - - - 0.000003965 49.0
HKD1_k127_7278519_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 452.0
HKD1_k127_7278519_1 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
HKD1_k127_7294786_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1226.0
HKD1_k127_7294786_1 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 3.932e-274 852.0
HKD1_k127_7294786_10 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 348.0
HKD1_k127_7294786_11 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
HKD1_k127_7294786_12 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 289.0
HKD1_k127_7294786_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
HKD1_k127_7294786_14 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000007076 113.0
HKD1_k127_7294786_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000008904 97.0
HKD1_k127_7294786_16 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000326 74.0
HKD1_k127_7294786_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 577.0
HKD1_k127_7294786_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 528.0
HKD1_k127_7294786_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 503.0
HKD1_k127_7294786_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 432.0
HKD1_k127_7294786_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 411.0
HKD1_k127_7294786_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 390.0
HKD1_k127_7294786_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 362.0
HKD1_k127_7294786_9 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 352.0
HKD1_k127_7308604_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.067e-213 674.0
HKD1_k127_7308604_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.678e-199 633.0
HKD1_k127_7308604_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000006146 78.0
HKD1_k127_7326995_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
HKD1_k127_7326995_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008809 265.0
HKD1_k127_7326995_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HKD1_k127_7326995_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001372 255.0
HKD1_k127_7326995_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000005311 162.0
HKD1_k127_7326995_5 - - - - 0.000000000000001078 87.0
HKD1_k127_7347380_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 407.0
HKD1_k127_7347380_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 302.0
HKD1_k127_7347380_2 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000001109 209.0
HKD1_k127_7347380_3 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000001666 157.0
HKD1_k127_7347380_5 - - - - 0.00000003341 56.0
HKD1_k127_7347380_6 Psort location Cytoplasmic, score 8.96 - - - 0.00006381 46.0
HKD1_k127_7357327_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582,K16201 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001841 274.0
HKD1_k127_7357327_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000007361 160.0
HKD1_k127_7357327_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000001718 75.0
HKD1_k127_7357327_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000005357 67.0
HKD1_k127_7357327_4 Bulb-type mannose-specific lectin - - - 0.000000005347 66.0
HKD1_k127_7357327_5 PFAM OmpA MotB domain protein K03640 - - 0.000000005776 64.0
HKD1_k127_7377889_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 538.0
HKD1_k127_7377889_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004958 273.0
HKD1_k127_7377889_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000002416 250.0
HKD1_k127_7377889_3 PFAM YbbR family protein - - - 0.0000000000000000000000000000001727 136.0
HKD1_k127_7377889_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000003739 66.0
HKD1_k127_7380663_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000005619 154.0
HKD1_k127_7390443_0 amidohydrolase K07045,K10220,K22213 - 4.1.1.52,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HKD1_k127_7390443_1 AIR synthase related protein, N-terminal domain K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 300.0
HKD1_k127_7390443_2 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.00000000000000000000000000000003001 134.0
HKD1_k127_7390443_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000005948 123.0
HKD1_k127_7390443_4 Putative regulatory protein - - - 0.000004848 55.0
HKD1_k127_7390585_0 AMP-binding enzyme C-terminal domain K00666 - - 1.676e-249 780.0
HKD1_k127_7390585_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 424.0
HKD1_k127_7390585_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004396 281.0
HKD1_k127_7390585_3 COG COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000001409 141.0
HKD1_k127_739308_0 NhaP-type Na H and K H - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 590.0
HKD1_k127_739308_1 NhaP-type Na H and K H - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 457.0
HKD1_k127_739308_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 439.0
HKD1_k127_739308_3 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 390.0
HKD1_k127_739308_4 NhaP-type Na H and K H - - - 0.00000000000000000000000000000000000000000000647 166.0
HKD1_k127_739308_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000003559 157.0
HKD1_k127_739308_6 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000747 134.0
HKD1_k127_739308_7 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.00000000000000000000000000001861 123.0
HKD1_k127_739308_8 PFAM CBS domain containing protein - - - 0.0000000001763 67.0
HKD1_k127_739308_9 - - - - 0.0000001051 57.0
HKD1_k127_740142_0 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 507.0
HKD1_k127_7428033_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1254.0
HKD1_k127_7428033_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 483.0
HKD1_k127_7428033_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 366.0
HKD1_k127_7428033_3 Dehydroquinase class II K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000108 184.0
HKD1_k127_7428033_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000008118 168.0
HKD1_k127_7428033_5 Tetratricopeptide repeat - - - 0.00000001625 63.0
HKD1_k127_7441254_0 oligoendopeptidase F - - - 0.00000000000000000000002303 114.0
HKD1_k127_7441254_1 sequence-specific DNA binding K18831 - - 0.00000000000002355 78.0
HKD1_k127_7449489_0 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 339.0
HKD1_k127_7449489_1 heme binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 319.0
HKD1_k127_7449489_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000009731 229.0
HKD1_k127_7449489_3 glyoxalase III activity - - - 0.000000000000000000000000004215 117.0
HKD1_k127_7449489_4 glyoxalase III activity - - - 0.00000000000000000000000002068 113.0
HKD1_k127_7449489_5 - - - - 0.00000000000000000000005335 106.0
HKD1_k127_7449489_6 DNA-binding transcription factor activity - - - 0.00000000000000000000009296 100.0
HKD1_k127_7449489_7 peptidase activity K01286 - 3.4.16.4 0.000000000000000000001243 100.0
HKD1_k127_7449489_8 - - - - 0.000000000000000003003 88.0
HKD1_k127_7487505_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 449.0
HKD1_k127_7487505_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
HKD1_k127_7487505_2 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000008112 153.0
HKD1_k127_753152_0 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 344.0
HKD1_k127_753152_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 286.0
HKD1_k127_753152_2 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000004022 148.0
HKD1_k127_753152_3 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.000000000000000016 82.0
HKD1_k127_753152_4 - - - - 0.0000000000000004454 83.0
HKD1_k127_753152_5 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.000000000197 61.0
HKD1_k127_7554691_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K19548 - 1.1.1.385 0.000000000000000000000000000000000000000000000000000000000000002606 226.0
HKD1_k127_7554691_1 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
HKD1_k127_7554691_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000001633 98.0
HKD1_k127_7566400_0 Circularly permuted ATP-grasp type 2 - - - 5.585e-230 719.0
HKD1_k127_7566400_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 398.0
HKD1_k127_7566400_2 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
HKD1_k127_7566400_3 Major facilitator Superfamily K03762,K12226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 305.0
HKD1_k127_7566400_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008597 265.0
HKD1_k127_7566400_5 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
HKD1_k127_7566400_6 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
HKD1_k127_7566400_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000208 117.0
HKD1_k127_7566400_8 SprT-like family - - - 0.000000000000001916 87.0
HKD1_k127_7566400_9 - - - - 0.00000000004099 74.0
HKD1_k127_7567441_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 591.0
HKD1_k127_7567441_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 301.0
HKD1_k127_7567441_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
HKD1_k127_7567441_3 COG0084 Mg-dependent DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
HKD1_k127_7567441_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000035 195.0
HKD1_k127_7567441_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000009024 72.0
HKD1_k127_7567441_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000002753 52.0
HKD1_k127_7567526_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 539.0
HKD1_k127_7567526_1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 338.0
HKD1_k127_7567526_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000004636 138.0
HKD1_k127_7567526_3 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000003549 49.0
HKD1_k127_7570506_0 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 303.0
HKD1_k127_7570506_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000001358 237.0
HKD1_k127_7570506_2 Major facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000009224 224.0
HKD1_k127_7570506_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000008741 117.0
HKD1_k127_7570506_4 - - - - 0.0000000000000008836 79.0
HKD1_k127_7570506_5 MarR family - - - 0.00000000000006134 78.0
HKD1_k127_7581342_0 Belongs to the ClpA ClpB family K03694 - - 9.672e-264 831.0
HKD1_k127_7581342_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
HKD1_k127_7581342_2 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 284.0
HKD1_k127_7581342_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000802 217.0
HKD1_k127_7581342_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000004982 178.0
HKD1_k127_7581342_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000001315 121.0
HKD1_k127_7581342_7 protein conserved in bacteria K09919 - - 0.0000000000000000000000004275 108.0
HKD1_k127_7581342_8 Transcription factor zinc-finger K09981 - - 0.0000000000007706 76.0
HKD1_k127_7591765_0 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 423.0
HKD1_k127_7591765_1 PFAM Pilus assembly protein PilO K02664 - - 0.0000000000000000000000004885 112.0
HKD1_k127_7591765_2 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000006444 76.0
HKD1_k127_7591765_3 assembly protein K02665 - - 0.0000000004778 68.0
HKD1_k127_7643847_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000009486 152.0
HKD1_k127_7643847_1 Methyltransferase domain K15256 - - 0.000000000000000000000000000009117 128.0
HKD1_k127_7658753_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1055.0
HKD1_k127_7658753_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 291.0
HKD1_k127_7658753_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
HKD1_k127_7658753_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001714 191.0
HKD1_k127_7658753_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000002716 149.0
HKD1_k127_7658753_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000006872 136.0
HKD1_k127_7658753_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000009727 54.0
HKD1_k127_7664765_0 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000002759 196.0
HKD1_k127_7664765_1 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000002414 160.0
HKD1_k127_7675812_0 CHAD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003302 290.0
HKD1_k127_7675812_1 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002346 280.0
HKD1_k127_7675812_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001586 250.0
HKD1_k127_7675812_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
HKD1_k127_7675812_4 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000007392 176.0
HKD1_k127_7675812_5 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000003337 153.0
HKD1_k127_7675812_6 CYTH - - - 0.00000000000000000000000000000000004657 149.0
HKD1_k127_7675812_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000007297 130.0
HKD1_k127_7676551_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 452.0
HKD1_k127_7676551_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 344.0
HKD1_k127_7676551_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004738 250.0
HKD1_k127_7677129_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 3.963e-260 831.0
HKD1_k127_7677129_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 460.0
HKD1_k127_7677129_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 358.0
HKD1_k127_7677129_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 340.0
HKD1_k127_7677129_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000004487 166.0
HKD1_k127_7677129_5 Phosphomethylpyrimidine kinase K00941 GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 0.0000000000000000000000000000009527 123.0
HKD1_k127_7677129_6 dehydratase K01724 - 4.2.1.96 0.00000000000000000000001383 102.0
HKD1_k127_7685480_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000004087 177.0
HKD1_k127_7685480_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000006174 104.0
HKD1_k127_7685480_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000002805 84.0
HKD1_k127_7685480_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000004358 84.0
HKD1_k127_7685480_4 - - - - 0.0000005218 58.0
HKD1_k127_7685480_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00001542 50.0
HKD1_k127_7685480_6 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0001348 45.0
HKD1_k127_768698_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.731e-213 678.0
HKD1_k127_768698_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 323.0
HKD1_k127_768698_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000003114 124.0
HKD1_k127_7709353_0 Pyruvate kinase K00873 - 2.7.1.40 7.215e-201 647.0
HKD1_k127_7709353_1 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 604.0
HKD1_k127_7709353_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 554.0
HKD1_k127_7709353_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 435.0
HKD1_k127_7709353_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000001402 209.0
HKD1_k127_7709353_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000195 155.0
HKD1_k127_7709353_6 transcriptional regulator - - - 0.00000000000000000000000000000000000003791 148.0
HKD1_k127_7709353_7 Integrase core domain K07497 - - 0.00000000000000000000000009493 107.0
HKD1_k127_7709353_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000009363 87.0
HKD1_k127_7709353_9 Vitamin K-dependent gamma-carboxylase - - - 0.0003126 51.0
HKD1_k127_7723659_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.928e-235 755.0
HKD1_k127_7723659_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HKD1_k127_7723659_2 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000001168 97.0
HKD1_k127_7723659_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000151 82.0
HKD1_k127_7744142_0 E1-E2 ATPase K17686 - 3.6.3.54 9.435e-265 835.0
HKD1_k127_7744142_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 459.0
HKD1_k127_7744142_2 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 408.0
HKD1_k127_7744142_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001033 183.0
HKD1_k127_7744142_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000001008 173.0
HKD1_k127_7744142_5 Cupredoxin-like domain - - - 0.000000000000000000000000000000000002938 141.0
HKD1_k127_7744142_6 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000003374 106.0
HKD1_k127_7768244_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
HKD1_k127_7768244_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000008694 59.0
HKD1_k127_7768244_2 MgtC family K07507 - - 0.0000663 50.0
HKD1_k127_7791604_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 3.942e-203 644.0
HKD1_k127_7791604_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000001047 126.0
HKD1_k127_7794396_0 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 423.0
HKD1_k127_7794396_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002265 186.0
HKD1_k127_7816598_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 559.0
HKD1_k127_7816598_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 505.0
HKD1_k127_7816598_2 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 401.0
HKD1_k127_7816598_3 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 370.0
HKD1_k127_7816598_4 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 365.0
HKD1_k127_7816598_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000009738 239.0
HKD1_k127_7816598_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000003073 158.0
HKD1_k127_7816598_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000223 144.0
HKD1_k127_7816598_8 proteolysis - - - 0.000000000000000000000000000002925 128.0
HKD1_k127_7816598_9 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000004305 94.0
HKD1_k127_7854254_0 Glycosyl hydrolase family 67 C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 425.0
HKD1_k127_7895757_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 473.0
HKD1_k127_7895757_1 tyrosine recombinase K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 323.0
HKD1_k127_7895757_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000002732 193.0
HKD1_k127_7895757_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000006422 186.0
HKD1_k127_7895757_4 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000002098 176.0
HKD1_k127_7909262_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1046.0
HKD1_k127_7909262_1 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 490.0
HKD1_k127_7909262_10 methyltransferase - - - 0.00000000000000000009346 93.0
HKD1_k127_7909262_11 regulatory protein, FmdB family - - - 0.0000000000000000001686 93.0
HKD1_k127_7909262_12 polysaccharide export K01991,K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000003871 68.0
HKD1_k127_7909262_13 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000005195 67.0
HKD1_k127_7909262_14 Enoyl-(Acyl carrier protein) reductase - - - 0.000001952 52.0
HKD1_k127_7909262_2 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 428.0
HKD1_k127_7909262_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002004 279.0
HKD1_k127_7909262_4 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
HKD1_k127_7909262_5 reductase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000001519 211.0
HKD1_k127_7909262_6 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000323 198.0
HKD1_k127_7909262_7 - - - - 0.0000000000000000000000000000000000000000000000000001191 194.0
HKD1_k127_7909262_8 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000003121 158.0
HKD1_k127_7909262_9 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K00782 - - 0.000000000000000000000000000006182 128.0
HKD1_k127_79170_0 Outer membrane efflux protein - - - 5.812e-198 644.0
HKD1_k127_79170_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
HKD1_k127_79170_2 CVNH domain - - - 0.00000000000000000000000000000000000001984 151.0
HKD1_k127_7951407_0 B12 binding domain K00548 - 2.1.1.13 0.0 1653.0
HKD1_k127_7951407_1 Heat shock 70 kDa protein K04043 - - 5.137e-235 741.0
HKD1_k127_7951407_10 - - - - 0.00000000000000005817 81.0
HKD1_k127_7951407_11 - - - - 0.00000000000007962 77.0
HKD1_k127_7951407_2 threonine synthase activity K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 595.0
HKD1_k127_7951407_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 385.0
HKD1_k127_7951407_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 390.0
HKD1_k127_7951407_5 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000002472 187.0
HKD1_k127_7951407_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000004576 180.0
HKD1_k127_7951407_7 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000411 156.0
HKD1_k127_7951407_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000002506 140.0
HKD1_k127_7951407_9 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000000000000000003114 130.0
HKD1_k127_7970165_0 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 382.0
HKD1_k127_7970165_1 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000002285 114.0
HKD1_k127_7970165_2 Trypsin-like peptidase domain - - - 0.00005384 48.0
HKD1_k127_8004341_0 FAD linked oxidases, C-terminal domain - - - 0.0 1063.0
HKD1_k127_8004341_1 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 465.0
HKD1_k127_8004341_10 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 293.0
HKD1_k127_8004341_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000003315 261.0
HKD1_k127_8004341_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
HKD1_k127_8004341_13 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000001132 217.0
HKD1_k127_8004341_14 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000363 197.0
HKD1_k127_8004341_15 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000003949 188.0
HKD1_k127_8004341_16 EVE domain - - - 0.000000000000000000000000000000000000000000000000006016 184.0
HKD1_k127_8004341_17 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000001109 157.0
HKD1_k127_8004341_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000008629 149.0
HKD1_k127_8004341_19 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.0000000000000000000000000000005722 130.0
HKD1_k127_8004341_2 COG0471 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 420.0
HKD1_k127_8004341_20 - - - - 0.0000000000000000000000000001711 121.0
HKD1_k127_8004341_21 COG3209 Rhs family protein - - - 0.000000000000000001133 96.0
HKD1_k127_8004341_22 - - - - 0.000000000000000002862 93.0
HKD1_k127_8004341_23 DNA polymerase Ligase (LigD) - - - 0.000000000001043 74.0
HKD1_k127_8004341_24 THIoesterase K18700 - 3.1.2.29 0.000000000008598 71.0
HKD1_k127_8004341_25 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000002301 62.0
HKD1_k127_8004341_26 PFAM AIG2 family protein - - - 0.000000001037 65.0
HKD1_k127_8004341_3 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 421.0
HKD1_k127_8004341_4 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 412.0
HKD1_k127_8004341_5 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 382.0
HKD1_k127_8004341_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 375.0
HKD1_k127_8004341_7 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 375.0
HKD1_k127_8004341_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 323.0
HKD1_k127_8004341_9 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 294.0
HKD1_k127_801044_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.187e-239 752.0
HKD1_k127_801044_1 protein histidine kinase activity K11383 - 2.7.13.3 2.186e-207 661.0
HKD1_k127_801044_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 589.0
HKD1_k127_801044_3 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000004525 192.0
HKD1_k127_831493_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.83e-250 786.0
HKD1_k127_831493_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 378.0
HKD1_k127_837994_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003073 272.0
HKD1_k127_837994_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000002062 231.0
HKD1_k127_837994_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000001197 211.0
HKD1_k127_837994_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000009043 167.0
HKD1_k127_837994_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000001643 129.0
HKD1_k127_837994_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00002578 47.0
HKD1_k127_844984_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 621.0
HKD1_k127_844984_1 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 487.0
HKD1_k127_844984_2 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000004131 121.0
HKD1_k127_844984_3 - - - - 0.0000000000000000000000004487 107.0
HKD1_k127_844984_4 Lipase (class 3) K01046 - 3.1.1.3 0.00000000000000005079 92.0
HKD1_k127_865048_0 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.000000000000000000000000000002905 127.0
HKD1_k127_865048_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000007559 103.0
HKD1_k127_865048_2 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000001949 98.0
HKD1_k127_865894_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 548.0
HKD1_k127_865894_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 291.0
HKD1_k127_865894_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001266 278.0
HKD1_k127_865894_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
HKD1_k127_865894_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000001734 134.0
HKD1_k127_865894_5 COG0589 Universal stress protein UspA and related K14055 - - 0.0000000000000003757 89.0
HKD1_k127_881834_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 362.0
HKD1_k127_881834_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000006625 215.0
HKD1_k127_881834_10 LssY C-terminus - - - 0.0007563 48.0
HKD1_k127_881834_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000003829 196.0
HKD1_k127_881834_3 LssY C-terminus - - - 0.0000000000000000000000000000000000000000001678 169.0
HKD1_k127_881834_4 LssY C-terminus - - - 0.0000000000000000000000000000000005434 137.0
HKD1_k127_881834_5 LssY C-terminus - - - 0.00000000000000000000000000000005966 132.0
HKD1_k127_881834_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000187 130.0
HKD1_k127_881834_7 LssY C-terminus - - - 0.00000000000000000000000001078 111.0
HKD1_k127_881834_8 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000002411 116.0
HKD1_k127_911846_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 610.0
HKD1_k127_911846_1 HAD-hyrolase-like K07025 - - 0.000000000000000000006202 101.0
HKD1_k127_912459_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004156 276.0
HKD1_k127_912459_1 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000000004023 204.0
HKD1_k127_912459_2 - - - - 0.00000000000000000000000000000009792 128.0
HKD1_k127_936977_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 350.0
HKD1_k127_936977_1 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002368 232.0
HKD1_k127_936977_2 PFAM Calcium calmodulin dependent protein kinase II Association - - - 0.000000000000000000000000013 113.0
HKD1_k127_936977_3 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000002485 59.0
HKD1_k127_936977_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00003024 47.0
HKD1_k127_936977_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0001959 47.0
HKD1_k127_963173_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 584.0
HKD1_k127_963173_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 527.0
HKD1_k127_963173_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 396.0
HKD1_k127_963173_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 359.0
HKD1_k127_963173_4 Pyridoxamine 5-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 326.0
HKD1_k127_963173_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000112 263.0
HKD1_k127_963173_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
HKD1_k127_963173_7 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000004335 172.0
HKD1_k127_963173_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000005796 143.0
HKD1_k127_966085_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 477.0
HKD1_k127_966085_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 369.0
HKD1_k127_966085_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000005126 226.0
HKD1_k127_975085_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1281.0
HKD1_k127_975085_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.543e-226 725.0
HKD1_k127_975085_10 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000001171 97.0
HKD1_k127_975085_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 423.0
HKD1_k127_975085_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 398.0
HKD1_k127_975085_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 381.0
HKD1_k127_975085_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000185 297.0
HKD1_k127_975085_6 DNA-binding transcription factor activity K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001263 249.0
HKD1_k127_975085_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000001803 236.0
HKD1_k127_975085_8 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003221 243.0
HKD1_k127_975085_9 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000001398 172.0
HKD1_k127_975585_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.46e-321 997.0
HKD1_k127_975585_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 528.0
HKD1_k127_975585_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 426.0
HKD1_k127_975585_3 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 415.0
HKD1_k127_975585_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
HKD1_k127_975585_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
HKD1_k127_975585_6 ABC-type multidrug transport system, ATPase and permease components K18890 - - 0.0000000000000000000000000000000000000000000000001924 192.0
HKD1_k127_975585_7 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000003381 150.0
HKD1_k127_975585_8 - - - - 0.0000000000000000000000000000009128 126.0
HKD1_k127_975585_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000001332 57.0
HKD1_k127_99015_0 SpoIIAA-like - - - 0.000000000000000000000000000000000000004264 149.0
HKD1_k127_99015_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000009883 147.0
HKD1_k127_996748_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
HKD1_k127_996748_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 301.0
HKD1_k127_996748_2 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000987 232.0
HKD1_k127_996748_3 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000000000000000000008231 140.0