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Overview

ID MAG01744
Name HKD1_bin.62
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Limisphaerales
Family UBA3939
Genus UBA3939
Species
Assembly information
Completeness (%) 84.54
Contamination (%) 1.04
GC content (%) 56.0
N50 (bp) 12,892
Genome size (bp) 3,424,527

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2845

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1003114_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 346.0
HKD1_k127_1003114_1 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000000002528 143.0
HKD1_k127_1022957_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1102.0
HKD1_k127_1022957_1 Glycosyl transferase family group 2 K03669 - - 7.601e-254 804.0
HKD1_k127_1022957_10 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000007137 214.0
HKD1_k127_1022957_11 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000004291 202.0
HKD1_k127_1022957_12 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.000000000000008814 85.0
HKD1_k127_1022957_2 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 1.089e-197 634.0
HKD1_k127_1022957_3 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 515.0
HKD1_k127_1022957_4 Proton-conducting membrane transporter K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 526.0
HKD1_k127_1022957_5 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 512.0
HKD1_k127_1022957_6 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 412.0
HKD1_k127_1022957_7 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 326.0
HKD1_k127_1022957_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 291.0
HKD1_k127_1022957_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
HKD1_k127_1066498_0 Cytochrome b/b6/petB K00412 - - 2.084e-224 712.0
HKD1_k127_1066498_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 418.0
HKD1_k127_1066498_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0005539 47.0
HKD1_k127_1066498_2 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 411.0
HKD1_k127_1066498_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 329.0
HKD1_k127_1066498_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HKD1_k127_1066498_5 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000000000000000000000000000000003169 194.0
HKD1_k127_1066498_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_1066498_7 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000004538 179.0
HKD1_k127_1066498_8 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000002141 103.0
HKD1_k127_1066498_9 Yip1 domain - - - 0.0004311 51.0
HKD1_k127_1082941_0 Cytochrome c - - - 0.0 1158.0
HKD1_k127_1082941_1 glycosyl hydrolase of K09955 - - 9.338e-266 827.0
HKD1_k127_1082941_2 long-chain fatty acid transporting porin activity - - - 2.024e-195 617.0
HKD1_k127_1088338_0 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 1.561e-283 891.0
HKD1_k127_1088338_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
HKD1_k127_1107788_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 507.0
HKD1_k127_1107788_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 419.0
HKD1_k127_1107788_2 3-dehydroquinate synthase K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 420.0
HKD1_k127_1107788_3 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 323.0
HKD1_k127_1107788_4 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 262.0
HKD1_k127_1107788_5 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000003576 158.0
HKD1_k127_1107788_6 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000003197 93.0
HKD1_k127_1107788_7 Carboxypeptidase regulatory-like domain - - - 0.0000001618 64.0
HKD1_k127_1107788_8 Carboxypeptidase regulatory-like domain - - - 0.0003502 49.0
HKD1_k127_1125135_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 568.0
HKD1_k127_1125135_1 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 519.0
HKD1_k127_1125135_2 kinase related to galactokinase and mevalonate kinase K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 486.0
HKD1_k127_1125135_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 366.0
HKD1_k127_1125135_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 304.0
HKD1_k127_1125135_5 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 304.0
HKD1_k127_1125135_6 Nucleotidyl transferase K15669 - 2.7.7.71 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
HKD1_k127_1125135_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006983 254.0
HKD1_k127_1125135_8 transketolase activity K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000001557 216.0
HKD1_k127_1134863_0 SMART Elongator protein 3 MiaB NifB - - - 3.146e-227 714.0
HKD1_k127_1134863_1 COG4263 Nitrous oxide reductase K00376 - 1.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 513.0
HKD1_k127_1134863_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000001812 158.0
HKD1_k127_1134863_11 diguanylate cyclase - - - 0.00000000000000000000000000000000000000006924 163.0
HKD1_k127_1134863_12 Major facilitator superfamily MFS_1 K08225 - - 0.000000000000000000000000000000000005576 144.0
HKD1_k127_1134863_13 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000006507 128.0
HKD1_k127_1134863_14 Winged helix DNA-binding domain - - - 0.0000000000000000000000005885 107.0
HKD1_k127_1134863_17 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000006384 83.0
HKD1_k127_1134863_18 - - - - 0.000000000007518 74.0
HKD1_k127_1134863_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 301.0
HKD1_k127_1134863_3 LytB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005113 248.0
HKD1_k127_1134863_4 - - - - 0.000000000000000000000000000000000000000000000000000000000007149 227.0
HKD1_k127_1134863_5 sulfuric ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000003624 207.0
HKD1_k127_1134863_6 - - - - 0.000000000000000000000000000000000000000000000000000000124 216.0
HKD1_k127_1134863_7 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000006991 195.0
HKD1_k127_1134863_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000006969 188.0
HKD1_k127_1134863_9 - - - - 0.0000000000000000000000000000000000000000000001358 177.0
HKD1_k127_1153522_0 Glycosyl hydrolase family 115 - - - 0.0 1211.0
HKD1_k127_1153522_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 431.0
HKD1_k127_1153522_2 general secretion pathway protein K02456,K02679 - - 0.000000000006939 76.0
HKD1_k127_1153522_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000002272 75.0
HKD1_k127_1169763_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1408.0
HKD1_k127_1169763_1 ABC1 family K03688 - - 1.905e-197 629.0
HKD1_k127_1169763_2 PFAM glycoside hydrolase family 9 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 597.0
HKD1_k127_1169763_3 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
HKD1_k127_1169763_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
HKD1_k127_1169763_5 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000009557 225.0
HKD1_k127_1169763_6 - - - - 0.0000000000000000000000000000009457 127.0
HKD1_k127_1169763_7 Transposase - - - 0.000000000000000000000000000002094 127.0
HKD1_k127_1183262_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 481.0
HKD1_k127_1183262_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 424.0
HKD1_k127_1183262_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000006374 100.0
HKD1_k127_1183262_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000005032 87.0
HKD1_k127_1183262_12 - - - - 0.000000000005262 75.0
HKD1_k127_1183262_13 domain protein K20276 - - 0.000000000007518 74.0
HKD1_k127_1183262_14 Polysaccharide biosynthesis protein - - - 0.00001215 53.0
HKD1_k127_1183262_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 371.0
HKD1_k127_1183262_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 291.0
HKD1_k127_1183262_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000748 273.0
HKD1_k127_1183262_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000007161 254.0
HKD1_k127_1183262_6 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000001301 242.0
HKD1_k127_1183262_7 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000006436 130.0
HKD1_k127_1183262_8 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000001106 112.0
HKD1_k127_1185574_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 5.312e-265 833.0
HKD1_k127_1185574_1 PFAM Acetyl-CoA hydrolase transferase - - - 2.762e-258 811.0
HKD1_k127_1185574_2 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004769 275.0
HKD1_k127_1185574_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001174 284.0
HKD1_k127_1185574_4 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000003722 210.0
HKD1_k127_1185574_5 photoreceptor activity - - - 0.000000000000000000000002815 103.0
HKD1_k127_121200_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.163e-308 962.0
HKD1_k127_121200_1 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 1.204e-206 653.0
HKD1_k127_121200_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000002687 178.0
HKD1_k127_121200_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000001053 149.0
HKD1_k127_121200_4 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000002351 134.0
HKD1_k127_121200_5 domain protein K20541 - - 0.0000000000000000004616 101.0
HKD1_k127_121200_6 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001934 87.0
HKD1_k127_121200_7 O-Antigen ligase - - - 0.0000000001146 74.0
HKD1_k127_121200_8 - - - - 0.00000000147 69.0
HKD1_k127_1214963_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1340.0
HKD1_k127_1214963_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 384.0
HKD1_k127_1214963_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 347.0
HKD1_k127_1214963_3 symporter activity K03307 - - 0.00000000000000009444 81.0
HKD1_k127_124014_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 527.0
HKD1_k127_124014_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 438.0
HKD1_k127_124014_2 PFAM GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
HKD1_k127_124014_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005301 255.0
HKD1_k127_124014_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000001617 222.0
HKD1_k127_124014_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.000000000000000000000000000000000000000000000000000000001522 216.0
HKD1_k127_124014_6 EVE domain - - - 0.000000000000000000000000000000000000000000000000005746 184.0
HKD1_k127_124014_7 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000008231 140.0
HKD1_k127_124014_8 peptidase activity, acting on L-amino acid peptides K09607 - - 0.000000000007867 77.0
HKD1_k127_124014_9 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.00005725 48.0
HKD1_k127_1248994_0 His Kinase A (phosphoacceptor) domain - - - 1.03e-221 717.0
HKD1_k127_1248994_1 ATP-binding region ATPase domain protein - - - 9.389e-209 670.0
HKD1_k127_1248994_10 - - - - 0.000000000000000001879 97.0
HKD1_k127_1248994_2 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 537.0
HKD1_k127_1248994_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 472.0
HKD1_k127_1248994_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 430.0
HKD1_k127_1248994_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 357.0
HKD1_k127_1248994_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 308.0
HKD1_k127_1248994_7 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
HKD1_k127_1248994_8 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals K07710 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000001652 188.0
HKD1_k127_1248994_9 PFAM Arginine-tRNA-protein transferase, C terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000953 140.0
HKD1_k127_1259634_0 type II secretion system protein E K02652 - - 1.522e-222 704.0
HKD1_k127_1259634_1 General secretory system II protein E domain protein K02454,K02652 - - 5.487e-203 648.0
HKD1_k127_1259634_10 general secretion pathway protein K02456,K02679 - - 0.0005313 51.0
HKD1_k127_1259634_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 462.0
HKD1_k127_1259634_3 type II secretion K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 449.0
HKD1_k127_1259634_4 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000000000002914 176.0
HKD1_k127_1259634_5 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000003386 116.0
HKD1_k127_1259634_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000001322 108.0
HKD1_k127_1259634_7 general secretion pathway protein K02456,K02650,K02679 - - 0.000001062 59.0
HKD1_k127_1259634_8 general secretion pathway protein K02456 - - 0.00001451 55.0
HKD1_k127_1259634_9 Pfam:N_methyl_2 - - - 0.0001802 52.0
HKD1_k127_1277286_0 ATPase activity - - - 1.038e-242 765.0
HKD1_k127_1277286_1 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 510.0
HKD1_k127_1277286_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 255.0
HKD1_k127_1277286_4 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000004016 236.0
HKD1_k127_1277286_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000005672 208.0
HKD1_k127_1277286_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000001736 150.0
HKD1_k127_1277286_7 von Willebrand factor type A domain - - - 0.00002688 55.0
HKD1_k127_1279326_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001786 251.0
HKD1_k127_1279326_1 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000000000000000000000000000000000005778 198.0
HKD1_k127_1279326_2 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000007072 189.0
HKD1_k127_1279326_3 Tetratricopeptide repeat - - - 0.00000000003128 74.0
HKD1_k127_1291459_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 588.0
HKD1_k127_1291459_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 324.0
HKD1_k127_1291459_2 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 353.0
HKD1_k127_1291459_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 292.0
HKD1_k127_1291459_4 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 261.0
HKD1_k127_1291459_5 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000004778 136.0
HKD1_k127_1291459_6 CotH kinase protein - - - 0.000000000000000000000004784 121.0
HKD1_k127_1291459_7 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - 0.000004427 54.0
HKD1_k127_1291459_8 Glutaredoxin-like domain (DUF836) - - - 0.00007865 48.0
HKD1_k127_1298862_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 507.0
HKD1_k127_1298862_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 427.0
HKD1_k127_1298862_10 - - - - 0.00000462 48.0
HKD1_k127_1298862_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 375.0
HKD1_k127_1298862_3 Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006493 264.0
HKD1_k127_1298862_4 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
HKD1_k127_1298862_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000001022 227.0
HKD1_k127_1298862_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000003813 219.0
HKD1_k127_1298862_7 - - - - 0.0000000000000000000001923 105.0
HKD1_k127_1298862_8 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000002101 93.0
HKD1_k127_1298862_9 Cytochrome c K00406,K08906 - - 0.00000000000000000004086 93.0
HKD1_k127_135154_0 Domain of Unknown Function (DUF1080) - - - 3.014e-195 619.0
HKD1_k127_135154_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 478.0
HKD1_k127_135154_2 Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000002229 198.0
HKD1_k127_135154_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000008343 94.0
HKD1_k127_135154_4 general secretion pathway protein K02456,K02679 - - 0.0000000000002403 80.0
HKD1_k127_1396505_0 PFAM Radical SAM superfamily - - - 1.813e-246 772.0
HKD1_k127_1396505_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 485.0
HKD1_k127_1396505_10 - - - - 0.000000000000000000000000000000007608 147.0
HKD1_k127_1396505_11 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000008483 111.0
HKD1_k127_1396505_12 - - - - 0.000000002534 63.0
HKD1_k127_1396505_13 Putative zinc-finger - - - 0.0000008862 55.0
HKD1_k127_1396505_14 S-layer domain-containing protein - - - 0.00001529 58.0
HKD1_k127_1396505_2 KR domain K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 397.0
HKD1_k127_1396505_3 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 316.0
HKD1_k127_1396505_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 290.0
HKD1_k127_1396505_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004309 277.0
HKD1_k127_1396505_6 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000004309 242.0
HKD1_k127_1396505_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
HKD1_k127_1396505_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001297 219.0
HKD1_k127_1396505_9 - - - - 0.00000000000000000000000000000000000000000000000000000000002849 222.0
HKD1_k127_1485217_0 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 306.0
HKD1_k127_1485217_1 ATP-dependent zinc metalloprotease FTSH K08955 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009507,GO:0009526,GO:0009536,GO:0009888,GO:0009941,GO:0010073,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048507,GO:0048856,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
HKD1_k127_1485217_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000193 151.0
HKD1_k127_1485217_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000001094 110.0
HKD1_k127_1485217_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000006074 68.0
HKD1_k127_1485217_5 Domain of unknown function (DUF4115) - - - 0.000000007655 64.0
HKD1_k127_151948_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.512e-268 846.0
HKD1_k127_151948_1 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 3.134e-243 773.0
HKD1_k127_151948_10 PD-(D/E)XK nuclease superfamily - - - 0.000000000001341 68.0
HKD1_k127_151948_11 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0002316 45.0
HKD1_k127_151948_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 605.0
HKD1_k127_151948_3 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 419.0
HKD1_k127_151948_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 375.0
HKD1_k127_151948_5 transmembrane transporter activity K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 383.0
HKD1_k127_151948_6 Kelch motif - - - 0.000000000000000000000000000000000000000000001062 173.0
HKD1_k127_151948_7 Peptidase family M50 - - - 0.000000000000000000000000000000000000007807 153.0
HKD1_k127_151948_8 - - - - 0.0000000000000000000000000000000002475 138.0
HKD1_k127_151948_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000006994 80.0
HKD1_k127_152038_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 617.0
HKD1_k127_152038_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 571.0
HKD1_k127_152038_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001912 240.0
HKD1_k127_1527502_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 451.0
HKD1_k127_1527502_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 432.0
HKD1_k127_1527502_2 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000004861 212.0
HKD1_k127_1527502_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000004236 180.0
HKD1_k127_1527502_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000002146 139.0
HKD1_k127_1527502_6 GMC oxidoreductase - - - 0.0000000004629 65.0
HKD1_k127_1527502_7 - - - - 0.000000007655 64.0
HKD1_k127_1593931_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 1.931e-195 622.0
HKD1_k127_1593931_1 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000000000000000001175 193.0
HKD1_k127_1593931_2 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000001682 131.0
HKD1_k127_1594341_0 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 7.349e-237 743.0
HKD1_k127_1594341_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 358.0
HKD1_k127_1594341_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 349.0
HKD1_k127_1594341_3 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 319.0
HKD1_k127_1594341_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008637 258.0
HKD1_k127_1594341_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007618 252.0
HKD1_k127_1594341_6 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000007004 124.0
HKD1_k127_1594341_7 O-Antigen ligase - - - 0.000000000000000000000001002 117.0
HKD1_k127_1612885_0 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 2248.0
HKD1_k127_1612885_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 8.738e-287 885.0
HKD1_k127_1612885_2 PFAM Conserved region in glutamate synthase - - - 6.375e-232 727.0
HKD1_k127_1612885_3 glutamate synthase - - - 0.000000213 53.0
HKD1_k127_1612885_4 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0002207 45.0
HKD1_k127_166244_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K07307 - - 0.0 1078.0
HKD1_k127_166244_1 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00366 - 1.7.7.1 3.908e-216 686.0
HKD1_k127_166244_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 464.0
HKD1_k127_166244_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 398.0
HKD1_k127_166244_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 376.0
HKD1_k127_166244_5 ABC transporter K02049,K15578,K15579 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
HKD1_k127_1675821_0 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 443.0
HKD1_k127_1675821_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 390.0
HKD1_k127_1675821_2 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000009029 248.0
HKD1_k127_1675821_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000001711 231.0
HKD1_k127_1675821_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000001246 60.0
HKD1_k127_1710551_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 484.0
HKD1_k127_1710551_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 410.0
HKD1_k127_1710551_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 316.0
HKD1_k127_1710551_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001118 260.0
HKD1_k127_1728631_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 1.651e-276 856.0
HKD1_k127_1728631_1 excinuclease ABC activity K03703 - - 0.000000000000000000009978 101.0
HKD1_k127_1728631_2 Dihydroneopterin aldolase - - - 0.00000000000007636 78.0
HKD1_k127_1728631_3 LexA DNA binding domain - - - 0.00000000000479 67.0
HKD1_k127_1754032_0 Peptidase M16 - - - 0.0 1138.0
HKD1_k127_1754032_1 Peptidase family M3 K08602 - - 2.206e-265 828.0
HKD1_k127_1754032_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000003882 200.0
HKD1_k127_1754032_11 Protein of unknown function (DUF520) - - - 0.000000000000000000000000000000000000000000004675 170.0
HKD1_k127_1754032_12 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000001405 169.0
HKD1_k127_1754032_13 Peptidase C39 family K06992 - - 0.00001941 55.0
HKD1_k127_1754032_14 - - - - 0.0002641 49.0
HKD1_k127_1754032_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 571.0
HKD1_k127_1754032_3 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 494.0
HKD1_k127_1754032_4 response regulator receiver K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 374.0
HKD1_k127_1754032_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 353.0
HKD1_k127_1754032_6 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 312.0
HKD1_k127_1754032_7 domain protein K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 299.0
HKD1_k127_1754032_8 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004603 259.0
HKD1_k127_1754032_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HKD1_k127_1768012_0 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 387.0
HKD1_k127_1768012_1 tRNA-splicing ligase RtcB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
HKD1_k127_1768012_2 - - - - 0.00000000000000000000000000000000002103 139.0
HKD1_k127_1768012_3 DinB family - - - 0.00000000000000000000000000000006052 135.0
HKD1_k127_1768012_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000001192 119.0
HKD1_k127_1768012_5 - - - - 0.00001617 50.0
HKD1_k127_1840379_0 Penicillin binding protein transpeptidase domain K03587,K08384 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 382.0
HKD1_k127_1840379_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 344.0
HKD1_k127_1840379_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
HKD1_k127_1840379_3 Cobalamin adenosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000009579 205.0
HKD1_k127_1840379_4 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000246 164.0
HKD1_k127_1840379_5 - - - - 0.00000000000000000000000000000006251 130.0
HKD1_k127_1840379_6 Belongs to the MraZ family K03925 - - 0.000000000000000703 83.0
HKD1_k127_1840379_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000003225 67.0
HKD1_k127_185013_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 445.0
HKD1_k127_185013_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 426.0
HKD1_k127_185013_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005069 271.0
HKD1_k127_185013_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000006564 186.0
HKD1_k127_185013_4 Sulfotransferase domain - - - 0.000000000000000002785 95.0
HKD1_k127_185013_5 methyltransferase - - - 0.000000001921 68.0
HKD1_k127_185013_6 Methyltransferase FkbM domain - - - 0.00000001746 63.0
HKD1_k127_185013_7 membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00004545 56.0
HKD1_k127_1855677_0 C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001258 289.0
HKD1_k127_1855677_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001031 276.0
HKD1_k127_1855677_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000001347 246.0
HKD1_k127_1855677_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001172 126.0
HKD1_k127_1855677_4 - - - - 0.00001482 56.0
HKD1_k127_1855677_5 CAAX protease self-immunity K07052 - - 0.00003746 53.0
HKD1_k127_1884871_0 Glycosyl hydrolases family 31 - - - 2.521e-222 713.0
HKD1_k127_1884871_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 341.0
HKD1_k127_1884871_2 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.000000000000000000000000000001229 129.0
HKD1_k127_1884871_3 Domain of unknown function (DUF1844) - - - 0.000000009692 64.0
HKD1_k127_1895330_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 489.0
HKD1_k127_1895330_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 362.0
HKD1_k127_1895330_2 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005713 252.0
HKD1_k127_1895330_3 ABC transporter, ATP-binding protein - - - 0.00000000000000005577 83.0
HKD1_k127_1974117_0 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 517.0
HKD1_k127_1974117_1 Cupin domain - - - 0.000000000000000000000000000000000000000001902 158.0
HKD1_k127_1974117_2 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000009153 149.0
HKD1_k127_1974117_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000001129 132.0
HKD1_k127_1974117_4 WG containing repeat - - - 0.00000000000002566 83.0
HKD1_k127_1974117_5 spore germination - - - 0.0000005975 61.0
HKD1_k127_1974117_7 PFAM KWG Leptospira - - - 0.0002197 47.0
HKD1_k127_2035904_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 585.0
HKD1_k127_2035904_1 hydroxyacid-oxoacid transhydrogenase activity K00001,K01714 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 429.0
HKD1_k127_2035904_10 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.00000001642 58.0
HKD1_k127_2035904_11 Pectate lyase - - - 0.000003978 51.0
HKD1_k127_2035904_12 general secretion pathway protein K02456,K02679 - - 0.0002211 51.0
HKD1_k127_2035904_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004044 280.0
HKD1_k127_2035904_3 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01676,K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007062 252.0
HKD1_k127_2035904_4 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000007301 230.0
HKD1_k127_2035904_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
HKD1_k127_2035904_6 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000000000000002497 186.0
HKD1_k127_2035904_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000003303 188.0
HKD1_k127_2035904_8 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000001699 146.0
HKD1_k127_2035904_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000005796 107.0
HKD1_k127_2045113_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.04e-288 906.0
HKD1_k127_2045113_1 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 589.0
HKD1_k127_2045113_10 AsmA-like C-terminal region K07289 - - 0.0003873 51.0
HKD1_k127_2045113_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 387.0
HKD1_k127_2045113_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002128 286.0
HKD1_k127_2045113_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000009282 233.0
HKD1_k127_2045113_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000006688 239.0
HKD1_k127_2045113_6 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000292 217.0
HKD1_k127_2045113_7 Ketosteroid isomerase-related protein - - - 0.0000000000000000000006285 100.0
HKD1_k127_2045113_8 - - - - 0.00000752 52.0
HKD1_k127_2045113_9 R3H domain K06346 - - 0.000009839 48.0
HKD1_k127_2067358_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 376.0
HKD1_k127_2067358_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 357.0
HKD1_k127_2067358_2 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009365 254.0
HKD1_k127_2067358_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000006946 204.0
HKD1_k127_2067358_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000006477 169.0
HKD1_k127_2067358_5 RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000007839 164.0
HKD1_k127_2067358_6 Protein of unknown function (DUF998) - - - 0.0000000000000000000000009884 112.0
HKD1_k127_2067358_8 Abhydrolase domain containing 18 - - - 0.000000002502 69.0
HKD1_k127_2067358_9 Glycosyltransferase like family 2 - - - 0.000001064 52.0
HKD1_k127_211144_0 Alpha-L-fucosidase K01206 - 3.2.1.51 1.253e-289 909.0
HKD1_k127_211144_1 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 1.747e-199 647.0
HKD1_k127_211144_2 Protein of unknown function (DUF1593) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 562.0
HKD1_k127_211144_3 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 413.0
HKD1_k127_211144_4 hydrolase, family 65, central catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 319.0
HKD1_k127_211144_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
HKD1_k127_211144_6 metallopeptidase activity K01179,K07004,K12548 - 3.2.1.4 0.00000000000000000000000000000000000000000000000001283 194.0
HKD1_k127_211144_7 Pfam Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000001858 68.0
HKD1_k127_212369_0 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 506.0
HKD1_k127_212369_1 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 521.0
HKD1_k127_212369_2 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 394.0
HKD1_k127_212369_3 Domain of unknown function K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
HKD1_k127_212369_4 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000001259 274.0
HKD1_k127_212369_5 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000006926 160.0
HKD1_k127_212369_6 - - - - 0.00003588 48.0
HKD1_k127_2127282_0 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 269.0
HKD1_k127_2127282_1 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009383 268.0
HKD1_k127_2127282_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
HKD1_k127_2127282_3 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000000000000000000000001433 182.0
HKD1_k127_2127282_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) - - - 0.000000000000000004474 85.0
HKD1_k127_2136433_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 306.0
HKD1_k127_2136433_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HKD1_k127_2136433_2 Histidine kinase K01991,K03413 - - 0.00000000000000000000000000008377 120.0
HKD1_k127_2136433_3 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000001384 108.0
HKD1_k127_2136433_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000006699 111.0
HKD1_k127_2144691_0 AcrB/AcrD/AcrF family - - - 0.0 1329.0
HKD1_k127_2144691_1 Alpha-L-arabinofuranosidase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 411.0
HKD1_k127_2144691_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 356.0
HKD1_k127_2144691_3 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 321.0
HKD1_k127_2144691_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000001905 225.0
HKD1_k127_2144691_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000001887 218.0
HKD1_k127_2144691_6 NifU-like N terminal domain - - - 0.00000000000000000000000000000000000000000000000001409 184.0
HKD1_k127_2144691_7 outer membrane efflux protein - - - 0.00000000000000000000000000000000008971 149.0
HKD1_k127_2144691_8 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000000007284 134.0
HKD1_k127_2144691_9 Transcriptional regulator - - - 0.000000000000000000000000004843 115.0
HKD1_k127_2151519_0 - - - - 0.0 2464.0
HKD1_k127_2151519_1 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 1.886e-290 900.0
HKD1_k127_2151519_2 Major facilitator Superfamily K03292,K16248 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 574.0
HKD1_k127_2151519_3 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 571.0
HKD1_k127_2151519_4 alcohol dehydrogenase K00008,K05351 - 1.1.1.14,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 502.0
HKD1_k127_2151519_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 314.0
HKD1_k127_2151519_6 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003745 278.0
HKD1_k127_2151519_7 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000002984 181.0
HKD1_k127_2151519_8 LysM domain - - - 0.00001692 55.0
HKD1_k127_2151519_9 O-Antigen ligase - - - 0.0002654 51.0
HKD1_k127_2175609_0 ATP-dependent helicase nuclease subunit A K16898 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 557.0
HKD1_k127_2175609_1 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 520.0
HKD1_k127_2175609_2 Beta-Casp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 373.0
HKD1_k127_2175609_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000007529 235.0
HKD1_k127_2175609_4 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000000000000008291 221.0
HKD1_k127_2175609_5 Pilus assembly protein PilX - - - 0.00000000000000000000006852 113.0
HKD1_k127_2175609_6 Domain of unknown function (DUF4412) - - - 0.000008563 57.0
HKD1_k127_2175609_7 SNAP receptor activity - - - 0.00002085 55.0
HKD1_k127_2222469_0 inositol 2-dehydrogenase activity - - - 5.286e-208 656.0
HKD1_k127_2222469_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 561.0
HKD1_k127_2222469_2 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 403.0
HKD1_k127_2225549_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 526.0
HKD1_k127_2225549_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 421.0
HKD1_k127_2225549_10 Histidine kinase K01768,K02482,K03406,K07647,K07653,K08475,K10125 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000004175 214.0
HKD1_k127_2225549_11 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000004637 174.0
HKD1_k127_2225549_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000001801 147.0
HKD1_k127_2225549_13 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000004896 156.0
HKD1_k127_2225549_14 polysaccharide export K01991 - - 0.000000000000000000000000000000006205 137.0
HKD1_k127_2225549_15 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.000000000000000000000006548 109.0
HKD1_k127_2225549_16 - - - - 0.0000000000000000000001122 106.0
HKD1_k127_2225549_17 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000004035 102.0
HKD1_k127_2225549_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000001375 104.0
HKD1_k127_2225549_19 Protein of unknown function (DUF465) - - - 0.0000000000003682 75.0
HKD1_k127_2225549_2 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 400.0
HKD1_k127_2225549_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 390.0
HKD1_k127_2225549_4 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 287.0
HKD1_k127_2225549_5 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001899 295.0
HKD1_k127_2225549_6 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002452 302.0
HKD1_k127_2225549_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000002276 234.0
HKD1_k127_2225549_8 Glycosyl transferases group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000003872 228.0
HKD1_k127_2225549_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000001954 209.0
HKD1_k127_2233392_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 6.243e-295 915.0
HKD1_k127_2233392_1 Rhamnogalacturonate lyase K18195 GO:0005575,GO:0005576 4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 602.0
HKD1_k127_2233392_10 Parallel beta-helix repeats - - - 0.0000000000000000004348 100.0
HKD1_k127_2233392_11 - - - - 0.000000000000004552 83.0
HKD1_k127_2233392_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000004266 70.0
HKD1_k127_2233392_13 RDD family K18481 - - 0.00000000000643 74.0
HKD1_k127_2233392_14 RDD family K18481 - - 0.0000000002547 71.0
HKD1_k127_2233392_15 RDD family K18481 - - 0.000000004359 65.0
HKD1_k127_2233392_16 RDD family K18481 - - 0.000000006012 67.0
HKD1_k127_2233392_17 Protein of unknown function (DUF1559) K02456 - - 0.000005623 58.0
HKD1_k127_2233392_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 519.0
HKD1_k127_2233392_3 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 486.0
HKD1_k127_2233392_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 384.0
HKD1_k127_2233392_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 358.0
HKD1_k127_2233392_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000001437 175.0
HKD1_k127_2233392_7 PFAM TM2 domain - - - 0.0000000000000000000000000004768 121.0
HKD1_k127_2233392_8 Protein of unknown function (DUF2752) - - - 0.00000000000000000000001317 104.0
HKD1_k127_2233392_9 integral membrane protein - - - 0.00000000000000000001313 103.0
HKD1_k127_2238509_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 595.0
HKD1_k127_2238509_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 565.0
HKD1_k127_2238509_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000123 109.0
HKD1_k127_2238509_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000002537 82.0
HKD1_k127_2238509_12 response regulator K02483,K07658,K07668 - - 0.000000000001369 79.0
HKD1_k127_2238509_13 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000005859 51.0
HKD1_k127_2238509_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 446.0
HKD1_k127_2238509_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 399.0
HKD1_k127_2238509_4 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 410.0
HKD1_k127_2238509_5 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000008491 244.0
HKD1_k127_2238509_6 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000002188 177.0
HKD1_k127_2238509_7 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000001055 154.0
HKD1_k127_2238509_8 GGDEF domain - - - 0.0000000000000000000000000000000000000519 158.0
HKD1_k127_2238509_9 Recombination protein O N terminal K03584 - - 0.00000000000000000000000003165 116.0
HKD1_k127_2241753_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 351.0
HKD1_k127_2241753_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003478 291.0
HKD1_k127_2241753_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000002255 212.0
HKD1_k127_2241753_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000005135 161.0
HKD1_k127_2241753_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000003306 158.0
HKD1_k127_2241753_5 Fic/DOC family - - - 0.0000000000000000000000000000000000000008682 155.0
HKD1_k127_2241753_6 RNA polymerase sigma factor K03088 - - 0.0000000000000000000004066 106.0
HKD1_k127_2241753_7 SpoVT / AbrB like domain - - - 0.000000000000000000002853 95.0
HKD1_k127_2261537_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000001881 218.0
HKD1_k127_2261537_1 response regulator K02485 - - 0.00000000000000000000000000000000000000000000000000003835 193.0
HKD1_k127_2261537_2 Belongs to the serpin family K13963 - - 0.000000000000000000008013 98.0
HKD1_k127_2411579_0 CoA-substrate-specific enzyme activase - - - 0.0 1424.0
HKD1_k127_2411579_1 membrane protein involved in D-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 411.0
HKD1_k127_2411579_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 322.0
HKD1_k127_2411579_3 - - - - 0.0000000000000000000000002399 117.0
HKD1_k127_2411579_4 Protein of unknown function (DUF1501) - - - 0.0000000000000000002817 95.0
HKD1_k127_2420416_0 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 8.675e-288 912.0
HKD1_k127_2420416_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 8.376e-232 733.0
HKD1_k127_2420416_2 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
HKD1_k127_2420416_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 368.0
HKD1_k127_2420416_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000054 256.0
HKD1_k127_2420416_5 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000001447 179.0
HKD1_k127_2420416_6 M6 family metalloprotease domain protein - - - 0.000002884 50.0
HKD1_k127_2420416_7 Beta-lactamase superfamily domain - - - 0.00003666 47.0
HKD1_k127_2466151_0 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000003472 178.0
HKD1_k127_2466151_1 - - - - 0.00000000000000000000000000000004527 136.0
HKD1_k127_2466151_2 Protein required for attachment to host cells - - - 0.00000000008063 70.0
HKD1_k127_2469643_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1138.0
HKD1_k127_2469643_1 Serine dehydratase beta chain - - - 2.507e-273 848.0
HKD1_k127_2469643_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 471.0
HKD1_k127_2469643_3 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 331.0
HKD1_k127_2469643_4 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 321.0
HKD1_k127_2469643_5 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003385 240.0
HKD1_k127_2469643_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000114 195.0
HKD1_k127_2469643_7 Pyruvate formate lyase-like K00656 - 2.3.1.54 0.0000000003413 61.0
HKD1_k127_2518812_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 485.0
HKD1_k127_2518812_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 395.0
HKD1_k127_2518812_2 Parallel beta-helix repeat K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005488 265.0
HKD1_k127_2518812_3 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000001068 229.0
HKD1_k127_2518812_4 - - - - 0.0000000000000000000000000000000000000000000000000002055 199.0
HKD1_k127_2518812_5 COGs COG1131 ABC-type multidrug transport system ATPase component K01990,K20459 - - 0.00000000000000000000000000000000000000000001002 172.0
HKD1_k127_2518812_6 Psort location CytoplasmicMembrane, score 10.00 K19341 - - 0.0000000000000000000000000000000001536 146.0
HKD1_k127_2634928_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 600.0
HKD1_k127_2634928_1 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 535.0
HKD1_k127_2634928_10 - - - - 0.00000000000000004075 91.0
HKD1_k127_2634928_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 452.0
HKD1_k127_2634928_3 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 446.0
HKD1_k127_2634928_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000005066 227.0
HKD1_k127_2634928_5 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000009407 190.0
HKD1_k127_2634928_6 PFAM lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000001174 178.0
HKD1_k127_2634928_7 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000211 139.0
HKD1_k127_2634928_8 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.0000000000000000000000013 107.0
HKD1_k127_2634928_9 - - - - 0.0000000000000000007895 88.0
HKD1_k127_2666369_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.783e-256 797.0
HKD1_k127_2666369_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.215e-242 764.0
HKD1_k127_2666369_10 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HKD1_k127_2666369_11 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002155 294.0
HKD1_k127_2666369_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
HKD1_k127_2666369_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000007771 258.0
HKD1_k127_2666369_14 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002985 250.0
HKD1_k127_2666369_15 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000004938 205.0
HKD1_k127_2666369_16 PFAM DNA topoisomerase type IA zn finger domain protein - - - 0.000000000000000000000000000000000000000000000000000003676 202.0
HKD1_k127_2666369_17 - - - - 0.00000000000000000000000000000000000000000000000000117 189.0
HKD1_k127_2666369_18 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000003614 172.0
HKD1_k127_2666369_19 competence protein - - - 0.000000000000000000000000000000000000000002288 164.0
HKD1_k127_2666369_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.273e-201 634.0
HKD1_k127_2666369_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000007063 115.0
HKD1_k127_2666369_21 PIN domain K19686 - - 0.00000000000000000000004844 103.0
HKD1_k127_2666369_22 CAAX protease self-immunity - - - 0.0000000000000000000319 107.0
HKD1_k127_2666369_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000001665 77.0
HKD1_k127_2666369_3 Uncharacterized conserved protein (DUF2075) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 585.0
HKD1_k127_2666369_4 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 442.0
HKD1_k127_2666369_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 424.0
HKD1_k127_2666369_6 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 364.0
HKD1_k127_2666369_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 353.0
HKD1_k127_2666369_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 351.0
HKD1_k127_2666369_9 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
HKD1_k127_267059_0 PfkB domain protein K00874 - 2.7.1.45 1.946e-199 625.0
HKD1_k127_267059_1 Type II/IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
HKD1_k127_267059_2 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000002402 205.0
HKD1_k127_267059_3 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000002561 140.0
HKD1_k127_267059_4 - - - - 0.00000000000000002581 84.0
HKD1_k127_267059_5 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.000000000001625 79.0
HKD1_k127_267059_6 Type II secretion system K02653 - - 0.00000008485 64.0
HKD1_k127_2683002_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1036.0
HKD1_k127_2683002_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 493.0
HKD1_k127_2683002_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 284.0
HKD1_k127_2683002_3 ERAD pathway - - - 0.000000000000000000000000000000000000000000000000000000000000004672 227.0
HKD1_k127_2683002_4 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000000000000754 202.0
HKD1_k127_2683002_5 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000003836 138.0
HKD1_k127_2683002_6 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000008397 112.0
HKD1_k127_2697256_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 6.385e-200 638.0
HKD1_k127_2697256_1 cell redox homeostasis K00382,K00520 - 1.16.1.1,1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 429.0
HKD1_k127_2697256_2 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
HKD1_k127_2697256_3 cell septum assembly - - - 0.000000000000000000000000000000000000003521 164.0
HKD1_k127_2697256_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000001034 141.0
HKD1_k127_2697256_5 Oxygen tolerance - - - 0.000000000000000000000000000000006745 143.0
HKD1_k127_2697256_6 tetratricopeptide repeat - - - 0.0000000000000000000000002129 115.0
HKD1_k127_2728005_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 531.0
HKD1_k127_2728005_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 411.0
HKD1_k127_2728005_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 371.0
HKD1_k127_2728005_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 303.0
HKD1_k127_2728005_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002524 278.0
HKD1_k127_2728005_5 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000005495 231.0
HKD1_k127_2728005_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000005738 169.0
HKD1_k127_2728005_7 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000004374 125.0
HKD1_k127_2728005_8 VanZ like family - - - 0.000000000000000000000000001094 119.0
HKD1_k127_2728005_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00002959 54.0
HKD1_k127_2732803_0 Alpha-L-arabinofuranosidase C-terminus - - - 2.67e-209 671.0
HKD1_k127_2732803_1 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 495.0
HKD1_k127_2732803_2 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 456.0
HKD1_k127_2732803_3 Enterochelin esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 355.0
HKD1_k127_2732803_4 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 344.0
HKD1_k127_2732803_5 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000001686 197.0
HKD1_k127_2732803_6 Putative esterase - - - 0.00000000000000000000000000000000000000000000000004726 192.0
HKD1_k127_274123_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 497.0
HKD1_k127_274123_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686 287.0
HKD1_k127_274123_2 Alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000001092 220.0
HKD1_k127_274123_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000001338 206.0
HKD1_k127_274123_4 - - - - 0.00000000000000000000000000000000000002927 151.0
HKD1_k127_274123_6 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.00000002837 57.0
HKD1_k127_2858816_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 469.0
HKD1_k127_2858816_1 transferase activity, transferring glycosyl groups K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000006984 216.0
HKD1_k127_2858816_2 domain, Protein K15125,K20276 - - 0.0000000000000000000000000000000001407 153.0
HKD1_k127_2858816_3 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000001447 134.0
HKD1_k127_2888382_0 Domain of unknown function (DUF4070) - - - 4.259e-231 724.0
HKD1_k127_2888382_1 SMP-30/Gluconolaconase/LRE-like region - - - 2.313e-213 698.0
HKD1_k127_2888382_2 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 2.055e-210 665.0
HKD1_k127_2888382_3 Carbohydrate binding module (family 6) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 526.0
HKD1_k127_2888382_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 377.0
HKD1_k127_2888382_5 cephalosporin-C deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003509 259.0
HKD1_k127_2888382_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001471 220.0
HKD1_k127_2888382_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000007458 210.0
HKD1_k127_2888382_8 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000002384 98.0
HKD1_k127_2888382_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000005296 59.0
HKD1_k127_2890557_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1112.0
HKD1_k127_2890557_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00381 - 1.8.1.2 2.905e-211 670.0
HKD1_k127_2890557_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000111 204.0
HKD1_k127_2890557_11 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000008557 78.0
HKD1_k127_2890557_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000007176 79.0
HKD1_k127_2890557_13 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.000000007438 57.0
HKD1_k127_2890557_2 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 476.0
HKD1_k127_2890557_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 465.0
HKD1_k127_2890557_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 425.0
HKD1_k127_2890557_5 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 403.0
HKD1_k127_2890557_6 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 396.0
HKD1_k127_2890557_7 PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 312.0
HKD1_k127_2890557_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 295.0
HKD1_k127_2890557_9 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000001055 231.0
HKD1_k127_2896190_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 534.0
HKD1_k127_2896190_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 362.0
HKD1_k127_2896190_2 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000001881 174.0
HKD1_k127_2896190_3 Pseudouridine synthase K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000001477 136.0
HKD1_k127_2896190_4 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.000000000000000000000000000006443 123.0
HKD1_k127_2896190_5 - - - - 0.00000006117 57.0
HKD1_k127_2901387_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.116e-229 723.0
HKD1_k127_2901387_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 455.0
HKD1_k127_2901387_10 HDOD domain K03088 - - 0.0000000000000000000000000000000000000000000000001959 185.0
HKD1_k127_2901387_11 - - - - 0.000000000000000000000000000000000000000001607 177.0
HKD1_k127_2901387_12 HNH endonuclease - - - 0.0000000000000000000000001672 117.0
HKD1_k127_2901387_13 - - - - 0.00000000000000000000005277 104.0
HKD1_k127_2901387_14 - - - - 0.00000000000000000006446 95.0
HKD1_k127_2901387_15 domain protein K03088,K20276 - - 0.00000000000001721 86.0
HKD1_k127_2901387_16 lipolytic acyl hydrolase (LAH) - - - 0.000005563 50.0
HKD1_k127_2901387_17 BlaR1 peptidase M56 - - - 0.00002055 55.0
HKD1_k127_2901387_18 MOSC N-terminal beta barrel domain K07140 - - 0.0001093 52.0
HKD1_k127_2901387_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 454.0
HKD1_k127_2901387_3 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 423.0
HKD1_k127_2901387_4 Leucine rich repeats (6 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 425.0
HKD1_k127_2901387_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 309.0
HKD1_k127_2901387_6 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002253 255.0
HKD1_k127_2901387_7 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000005362 228.0
HKD1_k127_2901387_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000001027 201.0
HKD1_k127_2901387_9 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000004512 203.0
HKD1_k127_2938852_0 Cytochrome c554 and c-prime - - - 0.0 1115.0
HKD1_k127_2938852_1 PFAM ASPIC UnbV domain protein - - - 7.594e-256 827.0
HKD1_k127_2938852_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002936 255.0
HKD1_k127_2938852_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000002222 213.0
HKD1_k127_2938852_12 AraC-like ligand binding domain - - - 0.000000000000000000000000000003982 126.0
HKD1_k127_2938852_13 ASPIC and UnbV - - - 0.0000000000000000000000006718 109.0
HKD1_k127_2938852_14 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000788 84.0
HKD1_k127_2938852_15 FMN-binding domain protein - - - 0.00000007353 62.0
HKD1_k127_2938852_16 - - - - 0.00001508 51.0
HKD1_k127_2938852_2 asparagine synthase K01953 - 6.3.5.4 4.504e-221 692.0
HKD1_k127_2938852_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 621.0
HKD1_k127_2938852_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 504.0
HKD1_k127_2938852_5 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system K02526 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 489.0
HKD1_k127_2938852_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 331.0
HKD1_k127_2938852_7 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001879 267.0
HKD1_k127_2938852_8 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004533 257.0
HKD1_k127_2938852_9 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008007 252.0
HKD1_k127_2947001_0 Amino acid adenylation domain - - - 3.211e-320 1017.0
HKD1_k127_2947001_1 Spermine/spermidine synthase domain - - - 1.165e-266 847.0
HKD1_k127_2947001_10 Segregation and condensation complex subunit ScpB - - - 0.00000000000000000000000000000000000004067 153.0
HKD1_k127_2947001_11 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000005268 103.0
HKD1_k127_2947001_12 Cupin domain - - - 0.00000000000000001852 89.0
HKD1_k127_2947001_13 Integral membrane protein TerC family - - - 0.00000000001007 72.0
HKD1_k127_2947001_14 - - - - 0.0000000001346 70.0
HKD1_k127_2947001_15 Belongs to the glycosyl hydrolase 2 family - - - 0.000003811 59.0
HKD1_k127_2947001_16 endonuclease exonuclease phosphatase K07004 - - 0.00002046 57.0
HKD1_k127_2947001_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 612.0
HKD1_k127_2947001_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 561.0
HKD1_k127_2947001_4 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 541.0
HKD1_k127_2947001_5 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 329.0
HKD1_k127_2947001_6 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 307.0
HKD1_k127_2947001_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
HKD1_k127_2947001_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000005333 196.0
HKD1_k127_2947001_9 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000009689 154.0
HKD1_k127_2954372_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 470.0
HKD1_k127_2954372_1 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 388.0
HKD1_k127_2954372_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 336.0
HKD1_k127_2954372_3 lipopolysaccharide N-acetylmannosaminouronosyltransferase activity K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002622 281.0
HKD1_k127_2954372_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007757 262.0
HKD1_k127_2954372_5 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000003 158.0
HKD1_k127_2954372_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000001383 83.0
HKD1_k127_2959245_0 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 342.0
HKD1_k127_2959245_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000001629 70.0
HKD1_k127_2960275_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 2.016e-214 693.0
HKD1_k127_2960275_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 323.0
HKD1_k127_2960275_2 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000002388 194.0
HKD1_k127_2960275_3 Immunoglobulin I-set domain protein K01179,K01406 - 3.2.1.4,3.4.24.40 0.0000000000000000000000007636 120.0
HKD1_k127_2960275_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000007969 106.0
HKD1_k127_2960275_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000000002132 89.0
HKD1_k127_2960275_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000003634 63.0
HKD1_k127_299359_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 501.0
HKD1_k127_299359_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 408.0
HKD1_k127_299359_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000001283 242.0
HKD1_k127_299359_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000002544 106.0
HKD1_k127_299359_4 mRNA binding K07339 - - 0.0000000000000000000008028 96.0
HKD1_k127_299359_5 NAD-dependent DNA ligase - - - 0.00000002486 56.0
HKD1_k127_3014614_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1420.0
HKD1_k127_3014614_1 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.0 1141.0
HKD1_k127_3014614_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 346.0
HKD1_k127_3014614_11 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 349.0
HKD1_k127_3014614_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 304.0
HKD1_k127_3014614_13 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004705 275.0
HKD1_k127_3014614_14 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000004964 186.0
HKD1_k127_3014614_15 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000008047 164.0
HKD1_k127_3014614_16 - - - - 0.0000000000000000000000000000000000000004439 156.0
HKD1_k127_3014614_17 protein secretion K15125 - - 0.000000000000000000000000000007594 121.0
HKD1_k127_3014614_18 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000006496 96.0
HKD1_k127_3014614_19 Protein of unknown function (DUF2959) - - - 0.000001017 58.0
HKD1_k127_3014614_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0 1024.0
HKD1_k127_3014614_20 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0003267 46.0
HKD1_k127_3014614_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.616e-240 755.0
HKD1_k127_3014614_4 Sulfate transporter antisigma-factor antagonist STAS - - - 2.256e-204 651.0
HKD1_k127_3014614_5 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 617.0
HKD1_k127_3014614_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 590.0
HKD1_k127_3014614_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 456.0
HKD1_k127_3014614_8 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 449.0
HKD1_k127_3014614_9 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 436.0
HKD1_k127_302403_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 366.0
HKD1_k127_302403_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000001087 192.0
HKD1_k127_302403_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000001818 175.0
HKD1_k127_302403_3 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000000003969 162.0
HKD1_k127_302403_4 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000002656 112.0
HKD1_k127_302403_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000001289 79.0
HKD1_k127_3048545_0 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 468.0
HKD1_k127_3048545_1 oxidoreductase activity, acting on diphenols and related substances as donors K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 302.0
HKD1_k127_3048545_2 oxidoreductase activity, acting on diphenols and related substances as donors K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001632 259.0
HKD1_k127_3048545_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000002837 207.0
HKD1_k127_3048545_4 oxidoreductase - - - 0.00000000000111 76.0
HKD1_k127_3048545_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000008991 74.0
HKD1_k127_3048545_6 PFAM Glycosyl transferase family 2 K09931 - - 0.00002587 57.0
HKD1_k127_3079276_0 cellulose binding - - - 1.271e-211 662.0
HKD1_k127_3079276_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 531.0
HKD1_k127_3079276_10 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000001818 164.0
HKD1_k127_3079276_11 YCII-related domain - - - 0.0000000000000000000000000000000000000008028 154.0
HKD1_k127_3079276_12 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000004875 145.0
HKD1_k127_3079276_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000003547 137.0
HKD1_k127_3079276_15 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000006194 109.0
HKD1_k127_3079276_16 L,D-transpeptidase catalytic domain - - - 0.0000000000000005514 89.0
HKD1_k127_3079276_17 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000006144 64.0
HKD1_k127_3079276_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 414.0
HKD1_k127_3079276_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 368.0
HKD1_k127_3079276_4 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
HKD1_k127_3079276_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003882 245.0
HKD1_k127_3079276_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000717 217.0
HKD1_k127_3079276_7 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000128 209.0
HKD1_k127_3079276_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000002599 210.0
HKD1_k127_3079276_9 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000000007973 193.0
HKD1_k127_30793_0 Pfam:Gp37_Gp68 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 384.0
HKD1_k127_30793_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 319.0
HKD1_k127_30793_2 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000001936 270.0
HKD1_k127_30793_3 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 0.0000000000000000000000000000973 121.0
HKD1_k127_30793_4 - - - - 0.000000004492 69.0
HKD1_k127_3113508_0 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 396.0
HKD1_k127_3113508_1 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
HKD1_k127_3113508_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 346.0
HKD1_k127_3113508_3 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 334.0
HKD1_k127_3113508_4 ISXO2-like transposase domain - - - 0.0000000002855 64.0
HKD1_k127_3113508_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000005365 56.0
HKD1_k127_3113508_6 ISXO2-like transposase domain - - - 0.0005692 43.0
HKD1_k127_3165735_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.204e-198 631.0
HKD1_k127_3165735_1 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 545.0
HKD1_k127_3165735_10 domain protein K20541 - - 0.000001365 59.0
HKD1_k127_3165735_2 CotH kinase protein K02487,K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 513.0
HKD1_k127_3165735_3 Acetyl xylan esterase (AXE1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
HKD1_k127_3165735_4 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 323.0
HKD1_k127_3165735_5 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
HKD1_k127_3165735_6 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000001712 236.0
HKD1_k127_3165735_7 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000001225 207.0
HKD1_k127_3165735_8 RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000000000000000000000000000000005116 192.0
HKD1_k127_3165735_9 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000001897 185.0
HKD1_k127_3175603_0 FtsK/SpoIIIE family - - - 0.0 1218.0
HKD1_k127_3175603_1 sigma-54 factor interaction domain-containing protein K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 491.0
HKD1_k127_3175603_11 Proteins of 100 residues with WXG - - - 0.00000000000000000000000000000000004707 135.0
HKD1_k127_3175603_12 Fibronectin type 3 domain - - - 0.000000000000000000000000000000006657 149.0
HKD1_k127_3175603_13 - - - - 0.00000000000000000000000000003258 124.0
HKD1_k127_3175603_14 Permease MlaE K02066 - - 0.000000000000000000000000002056 122.0
HKD1_k127_3175603_15 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000001514 106.0
HKD1_k127_3175603_16 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000007994 112.0
HKD1_k127_3175603_17 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000003171 108.0
HKD1_k127_3175603_18 - - - - 0.00000000000007417 77.0
HKD1_k127_3175603_19 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000001389 77.0
HKD1_k127_3175603_2 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 419.0
HKD1_k127_3175603_20 - - - - 0.0000000007026 70.0
HKD1_k127_3175603_21 - - - - 0.000000002929 60.0
HKD1_k127_3175603_22 Biopolymer transport protein K03559 - - 0.000000177 58.0
HKD1_k127_3175603_23 Mammalian cell entry related domain protein K02067 - - 0.00009064 54.0
HKD1_k127_3175603_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 404.0
HKD1_k127_3175603_4 PFAM ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 378.0
HKD1_k127_3175603_5 - - - - 0.000000000000000000000000000000000000000000000000000000000005464 224.0
HKD1_k127_3175603_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD1_k127_3175603_7 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000649 194.0
HKD1_k127_3175603_8 Histidine kinase K07693,K20971 - - 0.0000000000000000000000000000000000000000000000008174 201.0
HKD1_k127_3175603_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000003293 157.0
HKD1_k127_3183805_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 431.0
HKD1_k127_3183805_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 404.0
HKD1_k127_3183805_10 Histidine kinase - - - 0.00007244 48.0
HKD1_k127_3183805_11 Phosphoribosyl transferase domain K07100 - - 0.0005997 43.0
HKD1_k127_3183805_2 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 367.0
HKD1_k127_3183805_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 239.0
HKD1_k127_3183805_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000004478 132.0
HKD1_k127_3183805_6 Phosphoribosyl transferase domain K07100 - - 0.0000000000000001084 79.0
HKD1_k127_3183805_7 - - - - 0.000000000000007935 87.0
HKD1_k127_3183805_8 Sigma factor PP2C-like phosphatases - - - 0.0000000001133 68.0
HKD1_k127_319599_0 tRNA synthetases class I (W and Y) - - - 9.872e-195 615.0
HKD1_k127_319599_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000001855 160.0
HKD1_k127_3197918_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1723.0
HKD1_k127_3197918_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 514.0
HKD1_k127_3197918_10 - - - - 0.0000000000000000009793 89.0
HKD1_k127_3197918_11 Protein of unknwon function (DUF3008) - - - 0.000000000000002728 78.0
HKD1_k127_3197918_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 477.0
HKD1_k127_3197918_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 472.0
HKD1_k127_3197918_4 In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl- insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 306.0
HKD1_k127_3197918_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
HKD1_k127_3197918_6 mercury ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000001458 183.0
HKD1_k127_3197918_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000002979 171.0
HKD1_k127_3197918_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000004319 136.0
HKD1_k127_3197918_9 - K07283 - - 0.00000000000000000004397 99.0
HKD1_k127_3203678_0 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002399 278.0
HKD1_k127_3203678_1 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000003148 175.0
HKD1_k127_3203678_2 - - - - 0.000000000000000000000000000000000000000008459 160.0
HKD1_k127_3203678_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000001744 140.0
HKD1_k127_3203678_4 Protein of unknown function (DUF3788) - - - 0.0000000000000000000000000000000002223 142.0
HKD1_k127_3203678_5 - - - - 0.000000000000000000000000000000002492 139.0
HKD1_k127_3203678_6 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000499 118.0
HKD1_k127_3203678_7 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000001359 79.0
HKD1_k127_3204207_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
HKD1_k127_3204207_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004179 267.0
HKD1_k127_3204207_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000005158 115.0
HKD1_k127_3204207_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000005482 100.0
HKD1_k127_3210799_0 Alpha-L-fucosidase K01206,K07114,K07126 - 3.2.1.51 6.144e-236 740.0
HKD1_k127_3210799_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 603.0
HKD1_k127_3210799_2 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 443.0
HKD1_k127_3210799_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
HKD1_k127_3210799_4 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000002183 151.0
HKD1_k127_3225358_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 295.0
HKD1_k127_3225358_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000005116 228.0
HKD1_k127_3225358_2 - K01992 - - 0.000000000075 73.0
HKD1_k127_329595_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 402.0
HKD1_k127_329595_1 C-terminal domain of histone - - - 0.00000000000000000000000000000000000000000000000000000000000000000005392 235.0
HKD1_k127_329595_2 - - - - 0.00000000000000000000000001508 113.0
HKD1_k127_329595_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000001497 77.0
HKD1_k127_329595_4 Putative restriction endonuclease - - - 0.000001737 56.0
HKD1_k127_329595_5 Recombinase - - - 0.00008191 48.0
HKD1_k127_3305661_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 511.0
HKD1_k127_3305661_1 Type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000007696 246.0
HKD1_k127_3350341_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 349.0
HKD1_k127_3350341_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 317.0
HKD1_k127_3350341_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000006246 269.0
HKD1_k127_3350341_3 defense response to other organism K02395,K19220,K19223 GO:0005575,GO:0005576 - 0.00000000000001023 84.0
HKD1_k127_3354504_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 310.0
HKD1_k127_3354504_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
HKD1_k127_3354504_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000009031 184.0
HKD1_k127_3378261_0 Ras family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 316.0
HKD1_k127_3378261_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 304.0
HKD1_k127_3378261_2 phosphorelay signal transduction system K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001742 283.0
HKD1_k127_3378261_5 Roadblock/LC7 domain - - - 0.000000000000000000000000000001198 127.0
HKD1_k127_3378261_6 Lysin motif - - - 0.0000006511 57.0
HKD1_k127_3378261_7 Transglutaminase-like superfamily - - - 0.000001145 51.0
HKD1_k127_3408554_0 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 8.754e-287 910.0
HKD1_k127_3408554_1 Alpha-L-fucosidase K01206 - 3.2.1.51 1.453e-250 786.0
HKD1_k127_3408554_2 family 43 - - - 1.142e-202 653.0
HKD1_k127_3408554_3 COGs COG2382 Enterochelin esterase K07214 - - 0.00000000000000000000000000000000000000000000000000479 185.0
HKD1_k127_3408554_4 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000008091 178.0
HKD1_k127_3446083_0 Heat shock 70 kDa protein K04043 - - 2.786e-310 962.0
HKD1_k127_3446083_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 535.0
HKD1_k127_3446083_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000001353 226.0
HKD1_k127_3446083_3 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000008324 206.0
HKD1_k127_3446083_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000005158 108.0
HKD1_k127_3446083_6 - - - - 0.000000000000000000006134 96.0
HKD1_k127_3446083_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000005304 61.0
HKD1_k127_3488945_0 OPT oligopeptide transporter protein - - - 5.129e-215 683.0
HKD1_k127_3488945_1 Belongs to the ABC transporter superfamily K02031,K02032,K02034,K15583 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 467.0
HKD1_k127_3488945_2 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 457.0
HKD1_k127_3488945_4 - - - - 0.000000000000000004623 86.0
HKD1_k127_3488945_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000001026 59.0
HKD1_k127_3538554_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1449.0
HKD1_k127_3538554_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1017.0
HKD1_k127_3538554_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007523 243.0
HKD1_k127_3538554_11 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
HKD1_k127_3538554_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000001665 220.0
HKD1_k127_3538554_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000004072 209.0
HKD1_k127_3538554_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000004788 199.0
HKD1_k127_3538554_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000005289 192.0
HKD1_k127_3538554_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000001293 185.0
HKD1_k127_3538554_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000009391 177.0
HKD1_k127_3538554_18 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000007019 173.0
HKD1_k127_3538554_19 TPM domain - - - 0.0000000000000000000000000000000000000000003624 164.0
HKD1_k127_3538554_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 459.0
HKD1_k127_3538554_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000001368 147.0
HKD1_k127_3538554_21 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000001314 144.0
HKD1_k127_3538554_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000001554 137.0
HKD1_k127_3538554_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000006673 124.0
HKD1_k127_3538554_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000319 117.0
HKD1_k127_3538554_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000003666 114.0
HKD1_k127_3538554_26 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 - - 0.000000000000000000000000009869 113.0
HKD1_k127_3538554_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000004797 105.0
HKD1_k127_3538554_28 Ferredoxin - - - 0.00000000000000000252 84.0
HKD1_k127_3538554_29 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000004329 74.0
HKD1_k127_3538554_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 457.0
HKD1_k127_3538554_30 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001364 68.0
HKD1_k127_3538554_31 PFAM Forkhead-associated protein - - - 0.00000000001153 73.0
HKD1_k127_3538554_32 Ribosomal L29 protein K02904 - - 0.00000008084 56.0
HKD1_k127_3538554_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 354.0
HKD1_k127_3538554_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 301.0
HKD1_k127_3538554_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 289.0
HKD1_k127_3538554_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007191 274.0
HKD1_k127_3538554_8 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001714 272.0
HKD1_k127_3538554_9 LemA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001486 260.0
HKD1_k127_3559819_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 606.0
HKD1_k127_3559819_1 metalloendopeptidase activity K01392,K01414 - 3.4.24.15,3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 426.0
HKD1_k127_3559819_2 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 404.0
HKD1_k127_3559819_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 405.0
HKD1_k127_3559819_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000004231 149.0
HKD1_k127_3559819_6 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.000000000000004509 76.0
HKD1_k127_3570243_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001401 286.0
HKD1_k127_3570243_1 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000108 269.0
HKD1_k127_3570243_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000005181 188.0
HKD1_k127_3570243_3 Rhomboid family - - - 0.000000000000000000000000006104 121.0
HKD1_k127_3570369_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 494.0
HKD1_k127_3570369_1 Alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 479.0
HKD1_k127_3570369_2 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 347.0
HKD1_k127_3570369_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
HKD1_k127_3570369_5 NmrA-like family - - - 0.0000000000000000000000002272 108.0
HKD1_k127_3570369_6 Hep Hag repeat protein - - - 0.00000000000000000008344 104.0
HKD1_k127_3638703_0 LamB porin K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 558.0
HKD1_k127_3638703_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 501.0
HKD1_k127_3638703_2 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 295.0
HKD1_k127_3638703_3 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001701 282.0
HKD1_k127_3638703_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000501 188.0
HKD1_k127_3638703_5 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000003356 160.0
HKD1_k127_3638703_6 Penicillinase repressor - - - 0.00000000000000000000000000000000000687 140.0
HKD1_k127_3691900_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1206.0
HKD1_k127_3691900_1 nitrite transmembrane transporter activity - - - 2.3e-322 1001.0
HKD1_k127_3691900_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 317.0
HKD1_k127_3691900_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005139 232.0
HKD1_k127_3691900_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000008373 195.0
HKD1_k127_3691900_5 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000003321 126.0
HKD1_k127_3691900_6 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000009797 110.0
HKD1_k127_3713879_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 499.0
HKD1_k127_3713879_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 430.0
HKD1_k127_3713879_2 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 265.0
HKD1_k127_3713879_3 Acyl-protein synthetase, LuxE K06046 - 6.2.1.19 0.000000000000000000000000000000000000000000000000000000000000001104 233.0
HKD1_k127_3713879_4 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000004646 219.0
HKD1_k127_3713879_5 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000004599 212.0
HKD1_k127_3713879_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000006233 180.0
HKD1_k127_3713879_7 - - - - 0.000000000000005312 86.0
HKD1_k127_3721952_0 1,4-alpha-glucan branching enzyme activity K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 3.677e-276 867.0
HKD1_k127_3721952_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.596e-259 805.0
HKD1_k127_3721952_10 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000002546 217.0
HKD1_k127_3721952_11 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000064 222.0
HKD1_k127_3721952_12 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000368 198.0
HKD1_k127_3721952_13 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000004783 162.0
HKD1_k127_3721952_14 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000000000000000001151 147.0
HKD1_k127_3721952_15 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000001882 129.0
HKD1_k127_3721952_16 MgtC family K07507 - - 0.00000000000000000000001788 106.0
HKD1_k127_3721952_17 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000005846 100.0
HKD1_k127_3721952_18 DnaJ molecular chaperone homology domain - - - 0.00000000000000000005956 97.0
HKD1_k127_3721952_19 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.0000000000000000001258 96.0
HKD1_k127_3721952_2 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 3.734e-236 741.0
HKD1_k127_3721952_20 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000003635 84.0
HKD1_k127_3721952_21 MgtC SapB transporter K07507 - - 0.000000000041 67.0
HKD1_k127_3721952_22 TonB C terminal K03832 - - 0.0000003536 60.0
HKD1_k127_3721952_3 Cysteine-rich domain - - - 9.317e-217 677.0
HKD1_k127_3721952_4 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.719e-203 636.0
HKD1_k127_3721952_5 L-lactate permease K03303 - - 1.42e-200 638.0
HKD1_k127_3721952_6 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 471.0
HKD1_k127_3721952_7 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 414.0
HKD1_k127_3721952_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 342.0
HKD1_k127_3721952_9 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001144 256.0
HKD1_k127_3741925_0 Highly conserved protein containing a thioredoxin domain - - - 1.063e-222 715.0
HKD1_k127_3741925_1 Alpha amylase, catalytic domain K00690,K05343 - 2.4.1.7,3.2.1.1,5.4.99.16 8.67e-214 674.0
HKD1_k127_3741925_10 phospholipase Carboxylesterase - - - 0.000000000000000000000000003864 123.0
HKD1_k127_3741925_11 Domain of unknown function (DUF5060) - - - 0.00000005426 58.0
HKD1_k127_3741925_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 580.0
HKD1_k127_3741925_3 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 517.0
HKD1_k127_3741925_4 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 443.0
HKD1_k127_3741925_5 Pfam:DUF303 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 435.0
HKD1_k127_3741925_6 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
HKD1_k127_3741925_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003656 286.0
HKD1_k127_3741925_8 Enterochelin esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000875 207.0
HKD1_k127_3741925_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000003533 115.0
HKD1_k127_3759764_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1563.0
HKD1_k127_3759764_1 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 2.776e-233 730.0
HKD1_k127_3759764_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 513.0
HKD1_k127_3759764_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 358.0
HKD1_k127_3759764_4 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 328.0
HKD1_k127_3759764_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000004748 121.0
HKD1_k127_3759764_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003033 115.0
HKD1_k127_3759764_7 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000001942 92.0
HKD1_k127_3759764_9 Protein of unknown function (DUF1232) - - - 0.0001261 49.0
HKD1_k127_3775876_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.568e-310 966.0
HKD1_k127_3775876_1 Fibronectin type 3 domain - - - 7.266e-265 851.0
HKD1_k127_3775876_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 5.033e-218 689.0
HKD1_k127_3775876_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 560.0
HKD1_k127_3775876_4 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 549.0
HKD1_k127_3775876_5 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 396.0
HKD1_k127_3775876_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000007893 158.0
HKD1_k127_3775876_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000006654 160.0
HKD1_k127_3775876_8 Domains in Na-Ca exchangers and integrin-beta4 K01406 - 3.4.24.40 0.0000000000000000000000000000000000000001778 174.0
HKD1_k127_3775876_9 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000001252 116.0
HKD1_k127_378757_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 601.0
HKD1_k127_378757_1 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 486.0
HKD1_k127_378757_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 429.0
HKD1_k127_378757_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 365.0
HKD1_k127_378757_4 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 344.0
HKD1_k127_378757_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000324 163.0
HKD1_k127_378757_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000000000000002258 144.0
HKD1_k127_378757_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000009232 113.0
HKD1_k127_378757_8 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00007186 53.0
HKD1_k127_3805997_0 ferrous iron transmembrane transporter activity K04759 - - 8.922e-199 644.0
HKD1_k127_3805997_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 541.0
HKD1_k127_3805997_10 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
HKD1_k127_3805997_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000009576 225.0
HKD1_k127_3805997_12 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000004347 220.0
HKD1_k127_3805997_13 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000002141 205.0
HKD1_k127_3805997_14 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.00000000000000000000000000000000000000000000000000000485 204.0
HKD1_k127_3805997_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000002734 195.0
HKD1_k127_3805997_16 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000001911 183.0
HKD1_k127_3805997_17 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000003758 160.0
HKD1_k127_3805997_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000005052 163.0
HKD1_k127_3805997_19 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000293 153.0
HKD1_k127_3805997_2 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 510.0
HKD1_k127_3805997_20 OsmC-like protein K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.0000000000000000000000000000000000211 140.0
HKD1_k127_3805997_21 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000005738 125.0
HKD1_k127_3805997_22 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000004802 105.0
HKD1_k127_3805997_23 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002074 115.0
HKD1_k127_3805997_24 iron ion homeostasis K04758 GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874 - 0.0000000000000002846 81.0
HKD1_k127_3805997_25 phosphorelay signal transduction system - - - 0.0000000000000126 79.0
HKD1_k127_3805997_26 Binds directly to 16S ribosomal RNA K02968 - - 0.000000001814 62.0
HKD1_k127_3805997_27 - - - - 0.000002522 55.0
HKD1_k127_3805997_28 Hep Hag repeat protein - - - 0.000004603 53.0
HKD1_k127_3805997_29 FeoA domain - - - 0.0001684 50.0
HKD1_k127_3805997_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 460.0
HKD1_k127_3805997_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 432.0
HKD1_k127_3805997_5 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 354.0
HKD1_k127_3805997_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 353.0
HKD1_k127_3805997_7 Glutamine amidotransferase of anthranilate synthase K01658,K01664,K13497 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 276.0
HKD1_k127_3805997_8 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001011 249.0
HKD1_k127_3805997_9 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000004041 246.0
HKD1_k127_3828753_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 324.0
HKD1_k127_3828753_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HKD1_k127_3828753_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000001468 151.0
HKD1_k127_3828753_3 Two component transcriptional regulator, winged helix family K14981 - - 0.000004239 55.0
HKD1_k127_384596_0 with different specificities (related to short-chain alcohol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 319.0
HKD1_k127_384596_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000002137 189.0
HKD1_k127_384596_3 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000005841 155.0
HKD1_k127_3894745_0 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000001818 193.0
HKD1_k127_3894745_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000003552 162.0
HKD1_k127_3894745_2 - - - - 0.0000000000000000000000000000000000000000167 161.0
HKD1_k127_3894745_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000003847 139.0
HKD1_k127_3894745_4 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000785 134.0
HKD1_k127_3894745_5 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000008136 62.0
HKD1_k127_3899690_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 556.0
HKD1_k127_3899690_1 GvpD gas vesicle protein K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 552.0
HKD1_k127_3899690_10 RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000000000000000000000001155 220.0
HKD1_k127_3899690_11 photoreceptor activity - - - 0.0000000000000000000000000000000000000000002794 168.0
HKD1_k127_3899690_12 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000008672 129.0
HKD1_k127_3899690_13 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000001864 132.0
HKD1_k127_3899690_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 486.0
HKD1_k127_3899690_3 Anthranilate synthase component I K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 373.0
HKD1_k127_3899690_4 transporter MgtE K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 343.0
HKD1_k127_3899690_5 quinone binding K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 307.0
HKD1_k127_3899690_6 Pfam:Arch_ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
HKD1_k127_3899690_7 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
HKD1_k127_3899690_8 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000002592 282.0
HKD1_k127_3899690_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001183 265.0
HKD1_k127_3910905_0 Histidine biosynthesis protein HisG domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
HKD1_k127_3910905_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 364.0
HKD1_k127_3910905_10 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000001103 128.0
HKD1_k127_3910905_11 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001717 89.0
HKD1_k127_3910905_2 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 308.0
HKD1_k127_3910905_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
HKD1_k127_3910905_4 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 250.0
HKD1_k127_3910905_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002885 244.0
HKD1_k127_3910905_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000003826 224.0
HKD1_k127_3910905_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000002024 231.0
HKD1_k127_3910905_8 FabA-like domain - - - 0.00000000000000000000000000000000000000000001735 166.0
HKD1_k127_394208_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.155e-257 799.0
HKD1_k127_394208_1 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 416.0
HKD1_k127_394208_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 316.0
HKD1_k127_394208_3 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 262.0
HKD1_k127_394208_4 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001663 254.0
HKD1_k127_394208_5 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001783 199.0
HKD1_k127_394208_6 - - - - 0.00000000000000000000000000000002015 132.0
HKD1_k127_394208_7 GGDEF domain - - - 0.00000000000000000000001192 117.0
HKD1_k127_394208_8 metallopeptidase activity K01179 - 3.2.1.4 0.0000000000000000000002165 108.0
HKD1_k127_394208_9 PFAM Response regulator receiver domain K07658 - - 0.0000000000002422 83.0
HKD1_k127_3967492_0 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000000000000000000000000000000003469 207.0
HKD1_k127_3967492_1 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000008529 172.0
HKD1_k127_3967492_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000007283 141.0
HKD1_k127_3967492_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000001244 86.0
HKD1_k127_3967492_4 - K02172 - - 0.00000244 60.0
HKD1_k127_3967492_5 Protein of unknown function (DUF1559) - - - 0.0004651 51.0
HKD1_k127_3967645_0 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
HKD1_k127_3967645_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
HKD1_k127_3967645_2 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000001995 163.0
HKD1_k127_3967645_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000004802 151.0
HKD1_k127_4024485_0 AcrB/AcrD/AcrF family - - - 0.0 1075.0
HKD1_k127_4024485_1 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 302.0
HKD1_k127_4024485_2 GGDEF domain - - - 0.00000000000000000000000001496 124.0
HKD1_k127_4024485_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000007673 87.0
HKD1_k127_4024485_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000002671 77.0
HKD1_k127_4025333_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 504.0
HKD1_k127_4025333_1 Pyruvate:ferredoxin oxidoreductase core domain II K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 474.0
HKD1_k127_4025333_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 441.0
HKD1_k127_4025333_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 432.0
HKD1_k127_4025333_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 415.0
HKD1_k127_4025333_5 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
HKD1_k127_4025333_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008414 268.0
HKD1_k127_4025333_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000004201 150.0
HKD1_k127_4025333_8 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000006681 105.0
HKD1_k127_4025333_9 membrane K08972 - - 0.000000000000000004559 90.0
HKD1_k127_4028892_0 Dehydratase family K22396 - 4.2.1.82 8.194e-300 932.0
HKD1_k127_4028892_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.037e-250 784.0
HKD1_k127_4028892_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 349.0
HKD1_k127_4028892_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002567 279.0
HKD1_k127_4028892_12 organic acid phosphorylation K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000008896 256.0
HKD1_k127_4028892_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HKD1_k127_4028892_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000009244 208.0
HKD1_k127_4028892_15 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000004227 175.0
HKD1_k127_4028892_16 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000001586 172.0
HKD1_k127_4028892_17 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000006112 149.0
HKD1_k127_4028892_18 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000001048 144.0
HKD1_k127_4028892_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000002094 127.0
HKD1_k127_4028892_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 5.944e-202 638.0
HKD1_k127_4028892_21 Histidine kinase - - - 0.000000000000000001778 91.0
HKD1_k127_4028892_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000002297 83.0
HKD1_k127_4028892_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 576.0
HKD1_k127_4028892_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 461.0
HKD1_k127_4028892_5 COGs COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase K00042,K19647 - 1.1.1.291,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 454.0
HKD1_k127_4028892_6 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 383.0
HKD1_k127_4028892_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 387.0
HKD1_k127_4028892_8 PFAM ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 371.0
HKD1_k127_4028892_9 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 366.0
HKD1_k127_4029591_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 423.0
HKD1_k127_4029591_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 356.0
HKD1_k127_4029591_2 transmembrane transport K16052 - - 0.0000000000000000000000000000000000000000000000000000001642 203.0
HKD1_k127_4029591_3 response regulator receiver - - - 0.0000001627 61.0
HKD1_k127_4037945_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001891 268.0
HKD1_k127_4037945_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000009439 219.0
HKD1_k127_4037945_10 hyperosmotic response K04065 - - 0.0006244 52.0
HKD1_k127_4037945_2 - - - - 0.0000000000000000000000000000000000000000000006118 174.0
HKD1_k127_4037945_3 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000001077 168.0
HKD1_k127_4037945_4 Thioredoxin reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000247 162.0
HKD1_k127_4037945_5 beta-lactamase - - - 0.0000000000000000000000000000000000008078 153.0
HKD1_k127_4037945_6 Protein of unknown function (DUF3309) - - - 0.00000000000000006654 81.0
HKD1_k127_4037945_7 Bacterial protein of unknown function (DUF883) - - - 0.00000000001411 69.0
HKD1_k127_4037945_8 membrane - - - 0.00000003734 62.0
HKD1_k127_4040506_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 1.556e-215 687.0
HKD1_k127_4040506_1 ATPase activity K06027 - 3.6.4.6 8.265e-209 656.0
HKD1_k127_4040506_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 316.0
HKD1_k127_4040506_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000006488 238.0
HKD1_k127_4040506_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000002168 84.0
HKD1_k127_4041218_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 601.0
HKD1_k127_4041218_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 534.0
HKD1_k127_4041218_2 Domain of unknown function (DUF4861) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 458.0
HKD1_k127_4041218_3 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 346.0
HKD1_k127_4041218_4 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00065 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0033764,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000007116 238.0
HKD1_k127_4043500_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 311.0
HKD1_k127_4043500_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000007592 133.0
HKD1_k127_4043500_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000002517 114.0
HKD1_k127_4043500_4 Protein of unknown function (DUF1800) - - - 0.000107 49.0
HKD1_k127_4043500_5 ABC transporter K01990 - - 0.0001351 46.0
HKD1_k127_4043908_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2939.0
HKD1_k127_4043908_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.077e-227 720.0
HKD1_k127_4043908_10 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000003417 158.0
HKD1_k127_4043908_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000001467 134.0
HKD1_k127_4043908_12 Control of competence regulator ComK, YlbF/YmcA - - - 0.0000000000000000000002658 102.0
HKD1_k127_4043908_13 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000001559 80.0
HKD1_k127_4043908_14 histone H2A K63-linked ubiquitination - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000003121 71.0
HKD1_k127_4043908_15 - - - - 0.000000000004788 72.0
HKD1_k127_4043908_16 Papain family cysteine protease - - - 0.0003618 51.0
HKD1_k127_4043908_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 565.0
HKD1_k127_4043908_3 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 406.0
HKD1_k127_4043908_4 photoreceptor activity K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 356.0
HKD1_k127_4043908_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 325.0
HKD1_k127_4043908_6 epimerase K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 263.0
HKD1_k127_4043908_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000007623 239.0
HKD1_k127_4043908_8 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000002322 231.0
HKD1_k127_4043908_9 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000001522 203.0
HKD1_k127_4044776_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 441.0
HKD1_k127_4044776_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
HKD1_k127_4044776_10 Transcriptional regulator K07669 - - 0.00000000000000003155 89.0
HKD1_k127_4044776_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000003634 68.0
HKD1_k127_4044776_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000001952 55.0
HKD1_k127_4044776_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
HKD1_k127_4044776_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 321.0
HKD1_k127_4044776_4 cell wall binding repeat - - - 0.000000000000000000000000000000000000000000000000000000000005976 231.0
HKD1_k127_4044776_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001081 185.0
HKD1_k127_4044776_6 - - - - 0.000000000000000000000000000000000000000000009446 171.0
HKD1_k127_4044776_7 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000003545 167.0
HKD1_k127_4044776_8 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000005129 132.0
HKD1_k127_4044776_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000005133 107.0
HKD1_k127_4057356_0 Histidine Phosphotransfer domain K11527 - 2.7.13.3 7.411e-231 767.0
HKD1_k127_4057356_1 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 419.0
HKD1_k127_4057356_2 Two component, sigma54 specific, transcriptional regulator, Fis family K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004632 257.0
HKD1_k127_4057356_3 PFAM Stage II sporulation E family protein K01079,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000006212 242.0
HKD1_k127_4057356_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000001951 170.0
HKD1_k127_4057356_5 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.0000000003625 66.0
HKD1_k127_4057356_6 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000441 51.0
HKD1_k127_4062172_0 AcrB/AcrD/AcrF family - - - 0.0 1328.0
HKD1_k127_4062172_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1045.0
HKD1_k127_4062172_10 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
HKD1_k127_4062172_11 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 303.0
HKD1_k127_4062172_12 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
HKD1_k127_4062172_13 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003738 274.0
HKD1_k127_4062172_14 Flavoprotein K01598 - 4.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD1_k127_4062172_15 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006401 253.0
HKD1_k127_4062172_16 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000005515 233.0
HKD1_k127_4062172_17 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002113 229.0
HKD1_k127_4062172_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000001245 219.0
HKD1_k127_4062172_19 Guanylate kinase K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000006821 198.0
HKD1_k127_4062172_2 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 1.758e-238 774.0
HKD1_k127_4062172_20 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000001052 169.0
HKD1_k127_4062172_21 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000001104 176.0
HKD1_k127_4062172_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000001852 169.0
HKD1_k127_4062172_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000001113 161.0
HKD1_k127_4062172_24 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000002347 138.0
HKD1_k127_4062172_25 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000003161 137.0
HKD1_k127_4062172_26 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.000000000000000000000000000001033 142.0
HKD1_k127_4062172_27 Calx-beta domain - - - 0.000000000000000000000000005405 130.0
HKD1_k127_4062172_28 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000005189 104.0
HKD1_k127_4062172_29 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000001036 89.0
HKD1_k127_4062172_3 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 535.0
HKD1_k127_4062172_30 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000002571 70.0
HKD1_k127_4062172_32 Heat shock protein DnaJ domain protein - - - 0.00000008262 57.0
HKD1_k127_4062172_33 - - - - 0.00005627 51.0
HKD1_k127_4062172_34 Belongs to the peptidase S8 family - - - 0.0009029 50.0
HKD1_k127_4062172_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 531.0
HKD1_k127_4062172_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 497.0
HKD1_k127_4062172_6 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 433.0
HKD1_k127_4062172_7 synthase K15431,K16167,K16424,K19580 - 2.3.1.233,2.3.1.246,2.3.1.253 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 402.0
HKD1_k127_4062172_8 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
HKD1_k127_4062172_9 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 309.0
HKD1_k127_4069762_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 386.0
HKD1_k127_4069762_1 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.0000000000000000000000000000000000000000000000000000000000000003151 230.0
HKD1_k127_4069762_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
HKD1_k127_4069762_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000004001 141.0
HKD1_k127_4069762_4 EamA-like transporter family - - - 0.0000000000001015 77.0
HKD1_k127_4069762_5 PFAM Phosphorylase superfamily - - - 0.0000000001254 70.0
HKD1_k127_4071979_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 474.0
HKD1_k127_4071979_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 398.0
HKD1_k127_4071979_2 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
HKD1_k127_4071979_3 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000754 272.0
HKD1_k127_4071979_4 NAD-dependent DNA ligase - - - 0.0000000000000007482 83.0
HKD1_k127_4079975_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.517e-210 661.0
HKD1_k127_4079975_1 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 366.0
HKD1_k127_4079975_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003831 253.0
HKD1_k127_4079975_3 zeta toxin - - - 0.000000000000000000000006579 105.0
HKD1_k127_4079975_4 Protein conserved in bacteria - - - 0.000000000000002971 76.0
HKD1_k127_4079975_5 - - - - 0.0000002235 59.0
HKD1_k127_409661_0 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 361.0
HKD1_k127_409661_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 350.0
HKD1_k127_409661_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 293.0
HKD1_k127_409661_3 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
HKD1_k127_409661_4 TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000007775 211.0
HKD1_k127_409661_5 peptidase M23 - - - 0.0000000000000000000000000000000000000000000000003157 188.0
HKD1_k127_409661_6 - - - - 0.0002609 48.0
HKD1_k127_4115864_0 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 467.0
HKD1_k127_4115864_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 330.0
HKD1_k127_4115864_2 Cellulose Binding Domain Type IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009054 246.0
HKD1_k127_4132394_0 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001833 252.0
HKD1_k127_4132394_1 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000001992 168.0
HKD1_k127_4132394_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000001837 164.0
HKD1_k127_4132394_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000006919 128.0
HKD1_k127_4132394_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000006932 129.0
HKD1_k127_4132394_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000009676 99.0
HKD1_k127_4132394_6 Ribosomal protein L33 K02913 - - 0.00000000000000000002849 91.0
HKD1_k127_4132394_7 Ribosomal protein S18 K02963 - - 0.000000000000007432 77.0
HKD1_k127_4141963_0 Tryptophan halogenase - - - 3.341e-205 650.0
HKD1_k127_4141963_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 613.0
HKD1_k127_4141963_10 RNA recognition motif - - - 0.00000000000000000000000000008536 119.0
HKD1_k127_4141963_11 Methyltransferase domain - - - 0.00000000000000000000000009372 115.0
HKD1_k127_4141963_12 Phosphopantetheine attachment site - - - 0.0000000000000000000009762 97.0
HKD1_k127_4141963_13 - - - - 0.000368 49.0
HKD1_k127_4141963_14 Domain of Unknown Function (DUF748) - - - 0.0003772 48.0
HKD1_k127_4141963_2 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 470.0
HKD1_k127_4141963_3 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 465.0
HKD1_k127_4141963_4 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 393.0
HKD1_k127_4141963_5 biotin synthase activity K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 324.0
HKD1_k127_4141963_6 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002163 284.0
HKD1_k127_4141963_7 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 257.0
HKD1_k127_4141963_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000005894 194.0
HKD1_k127_4141963_9 response regulator K11444 - 2.7.7.65 0.0000000000000000000000000000000000009683 162.0
HKD1_k127_4142305_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.073e-248 777.0
HKD1_k127_4142305_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 410.0
HKD1_k127_4142305_2 membrane - - - 0.00000000000000000000000000004476 125.0
HKD1_k127_4142305_3 Predicted membrane protein (DUF2127) - - - 0.0000000000000162 80.0
HKD1_k127_4142305_4 - - - - 0.000000000000945 70.0
HKD1_k127_4150617_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2027.0
HKD1_k127_4150617_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.101e-256 811.0
HKD1_k127_4150617_10 F5 8 type C domain - - - 0.0001254 46.0
HKD1_k127_4150617_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001227 226.0
HKD1_k127_4150617_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000007015 209.0
HKD1_k127_4150617_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
HKD1_k127_4150617_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000004116 182.0
HKD1_k127_4150617_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000001672 168.0
HKD1_k127_4150617_7 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000000000000000000000397 177.0
HKD1_k127_4150617_8 F5 8 type C domain - - - 0.0000000000000000000000000000188 121.0
HKD1_k127_4150617_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000005453 95.0
HKD1_k127_4154966_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.852e-293 937.0
HKD1_k127_4154966_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 478.0
HKD1_k127_4154966_2 electron transfer activity K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 426.0
HKD1_k127_4154966_3 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001576 247.0
HKD1_k127_4154966_4 Signal transduction histidine kinase, LytS K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001603 239.0
HKD1_k127_4154966_5 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000001004 231.0
HKD1_k127_4154966_6 GDYXXLXY protein - - - 0.000000000000000000000000000000000000000000008217 176.0
HKD1_k127_4154966_7 electron transfer activity K03521 - - 0.00000000000000000002389 92.0
HKD1_k127_4159419_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 7.966e-227 723.0
HKD1_k127_4159419_1 Belongs to the ribulokinase family K00853 - 2.7.1.16 9.631e-220 694.0
HKD1_k127_4159419_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 606.0
HKD1_k127_4159419_3 ResB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 325.0
HKD1_k127_4159419_4 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 306.0
HKD1_k127_4159419_5 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001457 271.0
HKD1_k127_4159419_6 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000003448 169.0
HKD1_k127_4159419_7 - - - - 0.0000000000000000000000000000000000000000003106 173.0
HKD1_k127_4159419_8 Domain of unknown function K09955 - - 0.000000000000001318 79.0
HKD1_k127_4159419_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000001986 85.0
HKD1_k127_4163945_0 Glycosyltransferase Family 4 - - - 0.0 1045.0
HKD1_k127_4163945_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.244e-233 730.0
HKD1_k127_4163945_10 RNA recognition motif - - - 0.000000000000000000000000003401 113.0
HKD1_k127_4163945_11 Ribosomal protein L35 K02916 - - 0.00000000001338 68.0
HKD1_k127_4163945_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 593.0
HKD1_k127_4163945_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 403.0
HKD1_k127_4163945_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 315.0
HKD1_k127_4163945_5 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 319.0
HKD1_k127_4163945_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
HKD1_k127_4163945_7 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000002004 182.0
HKD1_k127_4163945_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000002632 187.0
HKD1_k127_4163945_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000004988 144.0
HKD1_k127_4235905_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.734e-225 703.0
HKD1_k127_4235905_1 Domain of unknown function (DUF3390) K18929 - - 3.703e-195 618.0
HKD1_k127_4235905_10 RibD C-terminal domain - - - 0.0000000000000000000000000000009532 131.0
HKD1_k127_4235905_11 Cupin 2, conserved barrel - - - 0.0000000000000000000000000007558 116.0
HKD1_k127_4235905_12 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.00000000000000000005206 93.0
HKD1_k127_4235905_13 PFAM PRC-barrel domain protein - - - 0.0000000003481 71.0
HKD1_k127_4235905_2 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 611.0
HKD1_k127_4235905_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 304.0
HKD1_k127_4235905_4 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000418 268.0
HKD1_k127_4235905_5 Fe-S oxidoreductase K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000186 246.0
HKD1_k127_4235905_6 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000003804 203.0
HKD1_k127_4235905_7 AIR carboxylase - - - 0.00000000000000000000000000000000000000000000000000000007294 199.0
HKD1_k127_4235905_8 cellulase activity K14274,K20276 - - 0.00000000000000000000000000000000000000000000000004358 196.0
HKD1_k127_4235905_9 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000003549 161.0
HKD1_k127_4248017_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 384.0
HKD1_k127_4248017_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
HKD1_k127_4248017_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
HKD1_k127_4248017_3 - - - - 0.0000000000000000000000000000000000000000000004662 175.0
HKD1_k127_4248017_4 NHL repeat containing protein - - - 0.0000000000000001511 83.0
HKD1_k127_4248017_5 PQQ-like domain - - - 0.00000000000249 72.0
HKD1_k127_4248017_6 - - - - 0.000001588 60.0
HKD1_k127_4273485_0 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 1.539e-256 819.0
HKD1_k127_4273485_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.07e-234 747.0
HKD1_k127_4273485_2 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 1.624e-232 740.0
HKD1_k127_4273485_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HKD1_k127_4273485_4 AMP-binding enzyme C-terminal domain K18660 - - 0.00000000000000000000000000000000000000000000000000000000000000000006123 233.0
HKD1_k127_4273485_5 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000004357 196.0
HKD1_k127_4273485_6 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000001671 168.0
HKD1_k127_4273485_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000002476 171.0
HKD1_k127_4273485_8 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000001626 145.0
HKD1_k127_4273485_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000111 134.0
HKD1_k127_4286240_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 2.874e-228 722.0
HKD1_k127_4286240_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 552.0
HKD1_k127_4286240_10 - - - - 0.000000000000000000000000000248 119.0
HKD1_k127_4286240_12 - - - - 0.000000005228 63.0
HKD1_k127_4286240_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 438.0
HKD1_k127_4286240_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 404.0
HKD1_k127_4286240_4 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 367.0
HKD1_k127_4286240_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 286.0
HKD1_k127_4286240_6 2Fe-2S -binding domain protein K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000002597 240.0
HKD1_k127_4286240_7 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000000000000000000535 171.0
HKD1_k127_4286240_8 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000156 169.0
HKD1_k127_4286240_9 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000002957 146.0
HKD1_k127_4286400_0 Aldehyde dehydrogenase family K04021 - - 2.954e-202 641.0
HKD1_k127_4286400_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.716e-199 649.0
HKD1_k127_4286400_10 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000006079 229.0
HKD1_k127_4286400_11 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
HKD1_k127_4286400_12 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000001037 209.0
HKD1_k127_4286400_13 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000001154 162.0
HKD1_k127_4286400_14 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000000000000000000000000000202 139.0
HKD1_k127_4286400_15 BMC - - - 0.000000000000000000000000000000000002141 140.0
HKD1_k127_4286400_16 BMC K04027 - - 0.000000000000000000000000000000001391 131.0
HKD1_k127_4286400_17 Kelch motif - - - 0.000000000000000000000000000004134 128.0
HKD1_k127_4286400_18 BMC - - - 0.000000000000000000000000000004446 122.0
HKD1_k127_4286400_19 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000007283 113.0
HKD1_k127_4286400_2 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 616.0
HKD1_k127_4286400_20 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000007727 123.0
HKD1_k127_4286400_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000004219 105.0
HKD1_k127_4286400_22 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000002003 99.0
HKD1_k127_4286400_23 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000001829 78.0
HKD1_k127_4286400_25 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00008471 54.0
HKD1_k127_4286400_3 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 484.0
HKD1_k127_4286400_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 479.0
HKD1_k127_4286400_5 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 355.0
HKD1_k127_4286400_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 349.0
HKD1_k127_4286400_7 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 314.0
HKD1_k127_4286400_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 278.0
HKD1_k127_4286400_9 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
HKD1_k127_4316543_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 532.0
HKD1_k127_4316543_1 Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 508.0
HKD1_k127_4316543_2 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
HKD1_k127_4316543_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 301.0
HKD1_k127_4316543_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001224 291.0
HKD1_k127_4316543_5 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000009158 177.0
HKD1_k127_4367790_0 TonB-dependent receptor K02014 - - 1.661e-205 658.0
HKD1_k127_4367790_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 531.0
HKD1_k127_4367790_2 protein histidine kinase activity K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 373.0
HKD1_k127_4367790_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 361.0
HKD1_k127_4367790_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001461 244.0
HKD1_k127_4367790_5 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000001053 166.0
HKD1_k127_4367790_6 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000000000009386 161.0
HKD1_k127_4367790_7 Response regulator, receiver - - - 0.0000000000000000000000000000000000000001517 158.0
HKD1_k127_4367790_8 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000001255 151.0
HKD1_k127_4428643_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 446.0
HKD1_k127_4428643_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 349.0
HKD1_k127_4428643_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 315.0
HKD1_k127_4428643_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HKD1_k127_4428643_4 Psort location Extracellular, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
HKD1_k127_4428643_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000002604 180.0
HKD1_k127_4428643_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000736 138.0
HKD1_k127_4428643_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000189 116.0
HKD1_k127_4439748_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 8.309e-228 732.0
HKD1_k127_4439748_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD1_k127_4439748_2 amino acid - - - 0.0000000174 56.0
HKD1_k127_4445802_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 554.0
HKD1_k127_4445802_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 463.0
HKD1_k127_4445802_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 402.0
HKD1_k127_4445802_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 404.0
HKD1_k127_4445802_4 Thioredoxin-like - - - 0.00000000000000000000000000000000000000008581 158.0
HKD1_k127_4445802_5 FHA domain - - - 0.00000000000005835 79.0
HKD1_k127_4445802_6 - - - - 0.0000004084 53.0
HKD1_k127_4445802_7 protein involved in exopolysaccharide biosynthesis - - - 0.0002554 50.0
HKD1_k127_4450091_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 322.0
HKD1_k127_4450091_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 298.0
HKD1_k127_4450091_2 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000001382 175.0
HKD1_k127_4450091_3 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000003445 136.0
HKD1_k127_4450091_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000004143 111.0
HKD1_k127_4450091_5 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000006635 61.0
HKD1_k127_4461697_0 TrkA-N domain - - - 5.705e-219 694.0
HKD1_k127_4461697_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000232 194.0
HKD1_k127_4461697_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0000000000000000000000000000000000000004474 158.0
HKD1_k127_4461697_3 protein conserved in bacteria - - - 0.000000000000000002328 97.0
HKD1_k127_4482474_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.002e-280 895.0
HKD1_k127_4482474_1 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 584.0
HKD1_k127_4482474_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 564.0
HKD1_k127_4482474_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000004464 211.0
HKD1_k127_4482474_4 Methionine biosynthesis protein MetW - - - 0.000000001102 68.0
HKD1_k127_4486359_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 1.22e-223 714.0
HKD1_k127_4486359_1 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 609.0
HKD1_k127_4486359_10 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
HKD1_k127_4486359_11 Alpha/beta hydrolase family K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
HKD1_k127_4486359_12 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004677 275.0
HKD1_k127_4486359_13 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004894 266.0
HKD1_k127_4486359_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000001041 262.0
HKD1_k127_4486359_15 Glycosyl transferase WecB/TagA/CpsF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000535 238.0
HKD1_k127_4486359_16 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000000004105 217.0
HKD1_k127_4486359_17 - - - - 0.0000000000000000000000000000000000000000000000000000000485 218.0
HKD1_k127_4486359_18 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000002539 198.0
HKD1_k127_4486359_19 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000232 59.0
HKD1_k127_4486359_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 603.0
HKD1_k127_4486359_20 Highly conserved protein containing a thioredoxin domain - - - 0.0001342 53.0
HKD1_k127_4486359_3 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 610.0
HKD1_k127_4486359_4 Alpha-L-fucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 499.0
HKD1_k127_4486359_5 Glycosyl hydrolases family 43 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 488.0
HKD1_k127_4486359_6 Enterochelin esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 430.0
HKD1_k127_4486359_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 415.0
HKD1_k127_4486359_8 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 393.0
HKD1_k127_4486359_9 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 369.0
HKD1_k127_4523955_0 4Fe-4S dicluster domain K00184 - - 1.252e-303 965.0
HKD1_k127_4523955_1 Polysulphide reductase, NrfD K00185 - - 1.445e-208 659.0
HKD1_k127_4523955_10 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 314.0
HKD1_k127_4523955_11 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 291.0
HKD1_k127_4523955_12 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001933 251.0
HKD1_k127_4523955_13 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
HKD1_k127_4523955_14 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000007888 203.0
HKD1_k127_4523955_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000001274 173.0
HKD1_k127_4523955_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000001678 145.0
HKD1_k127_4523955_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000004986 144.0
HKD1_k127_4523955_18 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000005475 151.0
HKD1_k127_4523955_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000005276 125.0
HKD1_k127_4523955_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 554.0
HKD1_k127_4523955_20 Uncharacterized small protein (DUF2292) - - - 0.00000001305 58.0
HKD1_k127_4523955_21 - - - - 0.00003355 52.0
HKD1_k127_4523955_22 Bacterial protein of unknown function (DUF883) - - - 0.0001125 48.0
HKD1_k127_4523955_3 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
HKD1_k127_4523955_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K10112,K16787 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358 3.6.3.25,3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 460.0
HKD1_k127_4523955_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 430.0
HKD1_k127_4523955_6 Sulfate ABC transporter, inner membrane subunit CysW K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 391.0
HKD1_k127_4523955_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 369.0
HKD1_k127_4523955_8 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 371.0
HKD1_k127_4523955_9 transport system K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 346.0
HKD1_k127_4674281_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 427.0
HKD1_k127_4674281_1 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 363.0
HKD1_k127_4674281_2 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 261.0
HKD1_k127_4674281_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000003254 186.0
HKD1_k127_4674281_4 - - - - 0.0000000002005 63.0
HKD1_k127_4682201_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 3.673e-241 759.0
HKD1_k127_4682201_1 (ABC) transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 607.0
HKD1_k127_4682201_2 ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 602.0
HKD1_k127_4682201_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 413.0
HKD1_k127_4689578_0 RecG wedge domain K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 531.0
HKD1_k127_4689578_1 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004712 265.0
HKD1_k127_4689578_2 SNAP receptor activity - - - 0.0000000000000000000001907 101.0
HKD1_k127_4689578_3 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000004838 89.0
HKD1_k127_4813016_0 the aldose L-fucose into the corresponding ketose L-fuculose K01818 - 5.3.1.25,5.3.1.3 4.773e-302 934.0
HKD1_k127_4813016_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 455.0
HKD1_k127_4813016_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
HKD1_k127_4813016_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002469 234.0
HKD1_k127_4813016_4 Predicted membrane protein (DUF2339) - - - 0.000000002515 70.0
HKD1_k127_4816463_0 Pyridine nucleotide-disulphide oxidoreductase K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 516.0
HKD1_k127_4816463_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 470.0
HKD1_k127_4816463_2 6-phosphogluconolactonase activity K20952 - - 0.0000000000000000000000000000000000000000000000000000005628 204.0
HKD1_k127_4816463_3 6-phosphogluconolactonase activity K20952 - - 0.0000000000000000000682 94.0
HKD1_k127_4816463_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470,K02622 - 5.99.1.3 0.000000000888 60.0
HKD1_k127_4816463_6 Acid phosphatase homologues - - - 0.0000005011 59.0
HKD1_k127_4867033_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 296.0
HKD1_k127_4867033_1 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003967 290.0
HKD1_k127_4867033_2 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000004692 254.0
HKD1_k127_4867033_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000001957 220.0
HKD1_k127_4867033_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000001756 198.0
HKD1_k127_4867033_5 PD-(D/E)XK nuclease superfamily - - - 0.0000000546 55.0
HKD1_k127_4879519_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 612.0
HKD1_k127_4879519_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 490.0
HKD1_k127_4879519_2 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 362.0
HKD1_k127_4879519_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 321.0
HKD1_k127_4879519_4 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 298.0
HKD1_k127_4879519_5 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000003797 230.0
HKD1_k127_4879519_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000000009001 146.0
HKD1_k127_48813_0 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000001191 216.0
HKD1_k127_48813_1 cell adhesion K20276 - - 0.00000000000000000000000000000000003171 155.0
HKD1_k127_48813_2 major outer membrane lipoprotein - - - 0.00000000000000000000000000000006261 131.0
HKD1_k127_48813_3 S-layer homology domain - - - 0.000000000005242 79.0
HKD1_k127_48813_4 IPT/TIG domain - - - 0.0000000002537 74.0
HKD1_k127_4889210_0 Anticodon binding domain K01880 - 6.1.1.14 6.453e-225 718.0
HKD1_k127_4889210_1 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 612.0
HKD1_k127_4889210_2 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 362.0
HKD1_k127_4889210_3 domain, Protein - - - 0.00000000000000000000000000000000199 143.0
HKD1_k127_4889210_4 domain protein - - - 0.00001472 57.0
HKD1_k127_4919392_0 Domain of unknown function (DUF4914) - - - 3.298e-300 932.0
HKD1_k127_4919392_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.21e-279 870.0
HKD1_k127_4919392_10 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000001686 205.0
HKD1_k127_4919392_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21030 - 2.7.7.40,2.7.7.60 0.000000000000000000000000000000000000000000001719 173.0
HKD1_k127_4919392_12 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000009215 165.0
HKD1_k127_4919392_13 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000001094 163.0
HKD1_k127_4919392_14 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000002394 98.0
HKD1_k127_4919392_15 Preprotein translocase subunit K03210 - - 0.00000000000009718 77.0
HKD1_k127_4919392_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 9.591e-246 778.0
HKD1_k127_4919392_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 613.0
HKD1_k127_4919392_4 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 460.0
HKD1_k127_4919392_5 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 411.0
HKD1_k127_4919392_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 395.0
HKD1_k127_4919392_7 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 325.0
HKD1_k127_4919392_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008411 273.0
HKD1_k127_4919392_9 Protein of unknown function DUF47 - - - 0.000000000000000000000000000000000000000000000000000000000000000001353 233.0
HKD1_k127_494669_0 dehydrogenase e1 component K00164 - 1.2.4.2 0.0 1152.0
HKD1_k127_494669_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 442.0
HKD1_k127_494669_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 394.0
HKD1_k127_494669_3 short-chain dehydrogenase reductase SDR K05886 - 1.1.1.276 0.0000000000000000000000000000000000000000000000000000000000000000001704 240.0
HKD1_k127_494669_4 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000001113 177.0
HKD1_k127_494669_5 TIGRFAM YD repeat protein - - - 0.00000001337 64.0
HKD1_k127_494669_6 bacterial OsmY and nodulation domain K04065 - - 0.00000001788 62.0
HKD1_k127_49523_0 Spermine/spermidine synthase domain - - - 6.952e-215 684.0
HKD1_k127_49523_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 452.0
HKD1_k127_49523_2 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 439.0
HKD1_k127_49523_3 BT1 family K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 361.0
HKD1_k127_49523_5 ubiquitin-protein transferase activity K20877 - 2.7.11.1 0.000003756 61.0
HKD1_k127_4963878_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 386.0
HKD1_k127_4963878_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 357.0
HKD1_k127_4963878_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 317.0
HKD1_k127_4963878_3 regulation of translation K03530 - - 0.000000000000000000000000000003377 122.0
HKD1_k127_4963878_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000007307 77.0
HKD1_k127_4966311_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1187.0
HKD1_k127_4966311_1 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005125 279.0
HKD1_k127_4966311_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000915 113.0
HKD1_k127_4966311_3 Hep Hag repeat protein K21449 - - 0.00000000000001752 76.0
HKD1_k127_4966311_4 domain, Protein K11904,K12132 - 2.7.11.1 0.00000001389 62.0
HKD1_k127_4996498_0 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 481.0
HKD1_k127_4996498_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
HKD1_k127_4996498_10 AsmA-like C-terminal region K07289 - - 0.00000002131 62.0
HKD1_k127_4996498_2 glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000005506 221.0
HKD1_k127_4996498_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000004687 160.0
HKD1_k127_4996498_5 - - - - 0.00000000000000000000001158 102.0
HKD1_k127_4996498_6 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001015 100.0
HKD1_k127_4996498_7 Protein of unknown function (DUF1015) - - - 0.0000000000000000000001334 100.0
HKD1_k127_4996498_8 KH domain K06960 - - 0.0000000000000004982 82.0
HKD1_k127_5026093_0 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 8.247e-256 802.0
HKD1_k127_5026093_1 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
HKD1_k127_5026093_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 301.0
HKD1_k127_5026093_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000004055 194.0
HKD1_k127_5026093_4 Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000009233 188.0
HKD1_k127_5026093_5 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000005723 161.0
HKD1_k127_5026093_6 Transcriptional regulator - - - 0.000000000000000000000000001421 115.0
HKD1_k127_5026093_7 peroxiredoxin activity - - - 0.00000000000000000000000001723 109.0
HKD1_k127_5026093_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000009504 109.0
HKD1_k127_5057480_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 3.071e-249 788.0
HKD1_k127_5057480_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005442 283.0
HKD1_k127_5057480_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000005285 174.0
HKD1_k127_5057480_3 Planctomycete cytochrome C - - - 0.00000000000000000000000000006866 128.0
HKD1_k127_5057480_4 AntiSigma factor - - - 0.00000000000000000007817 100.0
HKD1_k127_5057480_5 Pfam:N_methyl_2 - - - 0.00000000000005878 82.0
HKD1_k127_5057480_6 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00004033 54.0
HKD1_k127_5090407_0 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 3.749e-249 792.0
HKD1_k127_5090407_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 403.0
HKD1_k127_5090407_2 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000453 265.0
HKD1_k127_5090407_3 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000001566 169.0
HKD1_k127_5090407_4 Sulfatase-modifying factor enzyme 1 K02396,K03651 - 3.1.4.53 0.000000000000000000000000000000000000000006658 163.0
HKD1_k127_5090407_5 Cytidylyltransferase-like - - - 0.00000000000000000000000000000007246 138.0
HKD1_k127_5090407_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000001276 122.0
HKD1_k127_5093109_0 Protein conserved in bacteria K20274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 643.0
HKD1_k127_5093109_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 528.0
HKD1_k127_5093109_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 417.0
HKD1_k127_5093109_3 MafB19-like deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000005375 209.0
HKD1_k127_5093109_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000008084 177.0
HKD1_k127_5093109_5 cellulose binding - - - 0.000000000000000000000000008719 130.0
HKD1_k127_5093109_6 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000006305 95.0
HKD1_k127_5093109_7 FlgD Ig-like domain - - - 0.00000000000001754 89.0
HKD1_k127_5093109_8 amino acid activation for nonribosomal peptide biosynthetic process K01341,K20755 - 3.4.21.121,3.4.21.61 0.0000000006254 71.0
HKD1_k127_5106530_0 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.0 1223.0
HKD1_k127_5106530_1 Glycosyl-hydrolase 97 N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 589.0
HKD1_k127_5106530_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000008888 181.0
HKD1_k127_5106530_11 2-aminoethylphosphonate-pyruvate transaminase activity - - - 0.00000000000000000000000000000000000000000004458 186.0
HKD1_k127_5106530_12 Histidine kinase K02480,K07683 - 2.7.13.3 0.00000000000000000000000000000000000000001816 175.0
HKD1_k127_5106530_13 metallopeptidase activity K01179,K07004,K12548 - 3.2.1.4 0.000000000000000000000000000000126 143.0
HKD1_k127_5106530_14 PFAM response regulator receiver - - - 0.00000000000000000000000003147 113.0
HKD1_k127_5106530_15 domain protein K01051,K10297,K20844 - 3.1.1.11,3.2.1.55 0.00000000001493 79.0
HKD1_k127_5106530_16 general secretion pathway protein K02456 - - 0.00000000005028 72.0
HKD1_k127_5106530_17 Right handed beta helix region - - - 0.0000000115 68.0
HKD1_k127_5106530_18 Protein involved in outer membrane biogenesis K07289 - - 0.00009163 56.0
HKD1_k127_5106530_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 581.0
HKD1_k127_5106530_3 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 474.0
HKD1_k127_5106530_4 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 431.0
HKD1_k127_5106530_5 Belongs to the glycosyl hydrolase 30 family K15924 - 3.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 399.0
HKD1_k127_5106530_6 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 302.0
HKD1_k127_5106530_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
HKD1_k127_5106530_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000001157 210.0
HKD1_k127_5106530_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000001028 198.0
HKD1_k127_5118333_0 collagen metabolic process K08677 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 524.0
HKD1_k127_5118333_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 456.0
HKD1_k127_5118333_2 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 303.0
HKD1_k127_5118333_3 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000002205 239.0
HKD1_k127_5118333_4 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
HKD1_k127_5118333_5 Transcription termination factor nusG K05785 - - 0.0000000000000000000000000000006535 129.0
HKD1_k127_5118333_6 Chain length determinant protein - - - 0.00000000000000000000000000004672 131.0
HKD1_k127_5118333_7 Domain of unknown function (DUF5011) - - - 0.00000000005885 76.0
HKD1_k127_5126787_0 exo-alpha-(2->6)-sialidase activity - - - 3.493e-214 692.0
HKD1_k127_5126787_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
HKD1_k127_5126787_2 NIPSNAP family containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
HKD1_k127_5127439_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 481.0
HKD1_k127_5127439_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 431.0
HKD1_k127_5127439_2 PFAM ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 378.0
HKD1_k127_5127439_3 AraC-like ligand binding domain - - - 0.000000000000000000000000000006465 124.0
HKD1_k127_5127439_4 Autotransporter beta-domain - - - 0.000000000000000000005706 107.0
HKD1_k127_5130879_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.784e-225 717.0
HKD1_k127_5130879_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 556.0
HKD1_k127_5130879_10 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 256.0
HKD1_k127_5130879_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000024 245.0
HKD1_k127_5130879_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000002565 228.0
HKD1_k127_5130879_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000006095 213.0
HKD1_k127_5130879_14 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000004124 173.0
HKD1_k127_5130879_15 Belongs to the bacterial histone-like protein family K03530,K04764 - - 0.000000000000000000000000000000001879 132.0
HKD1_k127_5130879_16 metal cluster binding K06940 - - 0.000000000000000000000000008425 118.0
HKD1_k127_5130879_17 - - - - 0.0001684 50.0
HKD1_k127_5130879_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 531.0
HKD1_k127_5130879_3 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 518.0
HKD1_k127_5130879_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 473.0
HKD1_k127_5130879_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
HKD1_k127_5130879_6 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 401.0
HKD1_k127_5130879_7 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 385.0
HKD1_k127_5130879_8 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 317.0
HKD1_k127_5130879_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000009762 264.0
HKD1_k127_5172172_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.126e-246 766.0
HKD1_k127_5172172_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
HKD1_k127_5172172_10 Planctomycete cytochrome C - - - 0.000000000000000000000009406 106.0
HKD1_k127_5172172_11 - - - - 0.00000000000000000002121 101.0
HKD1_k127_5172172_12 cheY-homologous receiver domain K07712 - - 0.000000000000003105 77.0
HKD1_k127_5172172_13 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000315 70.0
HKD1_k127_5172172_14 Pyruvate phosphate dikinase - - - 0.0000000002625 72.0
HKD1_k127_5172172_15 Methyltransferase domain - - - 0.0000002893 63.0
HKD1_k127_5172172_16 - K07283 - - 0.000002352 59.0
HKD1_k127_5172172_17 peptidyl-tyrosine sulfation - - - 0.000003526 60.0
HKD1_k127_5172172_18 Biopolymer transport K03559 - - 0.00001443 53.0
HKD1_k127_5172172_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 370.0
HKD1_k127_5172172_3 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 315.0
HKD1_k127_5172172_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002134 270.0
HKD1_k127_5172172_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000009801 230.0
HKD1_k127_5172172_6 dUTPase - - - 0.000000000000000000000000000000000000000000000003825 189.0
HKD1_k127_5172172_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000029 174.0
HKD1_k127_5172172_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000004014 177.0
HKD1_k127_5172172_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000002346 141.0
HKD1_k127_5202109_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 397.0
HKD1_k127_5202109_1 - - - - 0.0000000000000000000000000000000000000000000002001 193.0
HKD1_k127_5202109_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003742 158.0
HKD1_k127_5202109_3 DNA mismatch endonuclease Vsr K07458 - - 0.0000000000000000000000000001088 119.0
HKD1_k127_5202109_4 May nick specific sequences that contain T G mispairs resulting from m5C-deamination - - - 0.0001734 48.0
HKD1_k127_5205266_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
HKD1_k127_5205266_1 CBS domain-containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 351.0
HKD1_k127_5205266_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000082 262.0
HKD1_k127_5205266_3 - - - - 0.000000000000000000000000002802 115.0
HKD1_k127_5205266_4 Belongs to the UPF0235 family K09131 - - 0.00000000000005859 76.0
HKD1_k127_5205266_5 - - - - 0.000000001784 63.0
HKD1_k127_5205266_6 cellulase activity - - - 0.0003433 53.0
HKD1_k127_5205266_7 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.0005076 46.0
HKD1_k127_52159_0 5TM C-terminal transporter carbon starvation CstA - - - 4.023e-284 888.0
HKD1_k127_52159_1 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 362.0
HKD1_k127_52159_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000007558 116.0
HKD1_k127_52159_11 PurA ssDNA and RNA-binding protein - - - 0.000000000000000000211 92.0
HKD1_k127_52159_12 helix-turn-helix- domain containing protein, AraC type K07720 - - 0.00000000000000008693 93.0
HKD1_k127_52159_13 - - - - 0.0000000000004124 78.0
HKD1_k127_52159_14 5TM C-terminal transporter carbon starvation CstA - - - 0.000000001611 61.0
HKD1_k127_52159_15 Protein of unknown function (DUF3991) - - - 0.0000002055 63.0
HKD1_k127_52159_2 GTP binding K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
HKD1_k127_52159_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000105 231.0
HKD1_k127_52159_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000003865 225.0
HKD1_k127_52159_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000001367 156.0
HKD1_k127_52159_6 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000032 155.0
HKD1_k127_52159_7 PadR family transcriptional regulator K10947 - - 0.0000000000000000000000000000000001501 136.0
HKD1_k127_52159_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000006376 130.0
HKD1_k127_52159_9 FecR protein - - - 0.000000000000000000000000000225 130.0
HKD1_k127_5263688_0 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 1.852e-227 720.0
HKD1_k127_5263688_1 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 436.0
HKD1_k127_5263688_10 acetyltransferase - - - 0.00000000000000000000000000000000000182 144.0
HKD1_k127_5263688_11 cellulose binding - - - 0.000000000000000000000741 108.0
HKD1_k127_5263688_12 LRR receptor-like serine threonine-protein kinase - - - 0.000000000000000001941 96.0
HKD1_k127_5263688_13 Protein of unknown function (DUF2905) - - - 0.000000000000000002093 86.0
HKD1_k127_5263688_15 COG0322 Nuclease subunit of the excinuclease complex - - - 0.0008791 47.0
HKD1_k127_5263688_2 ABC transporter K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 439.0
HKD1_k127_5263688_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 351.0
HKD1_k127_5263688_4 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 357.0
HKD1_k127_5263688_5 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 327.0
HKD1_k127_5263688_6 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 329.0
HKD1_k127_5263688_7 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 317.0
HKD1_k127_5263688_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
HKD1_k127_5263688_9 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
HKD1_k127_526579_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1233.0
HKD1_k127_526579_1 Bacterial protein of unknown function (DUF885) - - - 9.862e-203 647.0
HKD1_k127_526579_10 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000007574 140.0
HKD1_k127_526579_11 Histidine kinase K07636 - 2.7.13.3 0.000001311 56.0
HKD1_k127_526579_12 oxidoreductase activity - - - 0.00002193 57.0
HKD1_k127_526579_13 CotH kinase protein - - - 0.0003563 56.0
HKD1_k127_526579_14 xyloglucan:xyloglucosyl transferase activity K07004 - - 0.0004687 55.0
HKD1_k127_526579_2 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 499.0
HKD1_k127_526579_3 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 429.0
HKD1_k127_526579_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 396.0
HKD1_k127_526579_5 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 379.0
HKD1_k127_526579_6 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
HKD1_k127_526579_7 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000002771 190.0
HKD1_k127_526579_8 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000003338 188.0
HKD1_k127_526579_9 Erythromycin esterase - - - 0.0000000000000000000000000000000000002723 166.0
HKD1_k127_5270874_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.073e-235 742.0
HKD1_k127_5270874_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 400.0
HKD1_k127_5270874_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 299.0
HKD1_k127_5270874_3 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000001642 239.0
HKD1_k127_5285234_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 440.0
HKD1_k127_5285234_1 Elongator protein 3, MiaB family, Radical SAM K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 399.0
HKD1_k127_5285234_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000001708 134.0
HKD1_k127_5285234_3 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000001531 102.0
HKD1_k127_5285234_4 ABC transporter ATP-binding K01990 - - 0.00000000000001003 77.0
HKD1_k127_5285234_5 - - - - 0.00000000000179 76.0
HKD1_k127_5296953_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000659 207.0
HKD1_k127_5296953_1 - - - - 0.0000000000000000000000000000000000003482 146.0
HKD1_k127_5296953_2 Parallel beta-helix repeats - - - 0.000006062 57.0
HKD1_k127_5325299_0 LVIVD repeat - - - 0.0 1214.0
HKD1_k127_5325299_1 Glycosyl hydrolases family 2, sugar binding domain - - - 0.0 1163.0
HKD1_k127_5325299_10 rRNA (cytosine-C5-)-methyltransferase activity K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 366.0
HKD1_k127_5325299_11 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916 - 1.14.12.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 358.0
HKD1_k127_5325299_12 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 344.0
HKD1_k127_5325299_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 299.0
HKD1_k127_5325299_14 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000005708 213.0
HKD1_k127_5325299_15 - - - - 0.00000000000000000000000000000000000000000000000000001476 212.0
HKD1_k127_5325299_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000751 152.0
HKD1_k127_5325299_17 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000001085 160.0
HKD1_k127_5325299_18 Cytochrome c3 - - - 0.000000000000000000000000000000001208 149.0
HKD1_k127_5325299_19 - - - - 0.0000000000000000000000000000001953 133.0
HKD1_k127_5325299_2 TIGRFAM UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 594.0
HKD1_k127_5325299_20 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000001396 124.0
HKD1_k127_5325299_21 - - - - 0.000000000000000000008431 97.0
HKD1_k127_5325299_22 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000001698 87.0
HKD1_k127_5325299_23 histidine kinase HAMP region domain protein - - - 0.00000001267 61.0
HKD1_k127_5325299_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 496.0
HKD1_k127_5325299_4 6-phospho-beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 481.0
HKD1_k127_5325299_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 482.0
HKD1_k127_5325299_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 447.0
HKD1_k127_5325299_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 422.0
HKD1_k127_5325299_8 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 385.0
HKD1_k127_5325299_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 360.0
HKD1_k127_5355203_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.706e-287 890.0
HKD1_k127_5355203_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 621.0
HKD1_k127_5355203_10 Cytochrome c K12263 - - 0.0000000000000000000000000000000000000000000000000005367 196.0
HKD1_k127_5355203_11 Arylsulfotransferase Ig-like domain K01023 - 2.8.2.22 0.0000000000000000000000000000000000000000005109 178.0
HKD1_k127_5355203_12 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000000001036 166.0
HKD1_k127_5355203_13 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000004003 156.0
HKD1_k127_5355203_14 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000003255 147.0
HKD1_k127_5355203_15 TIGRFAM phosphocarrier, HPr family K11189 - - 0.000000000000000000000000000000006554 129.0
HKD1_k127_5355203_16 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000002342 126.0
HKD1_k127_5355203_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000001213 102.0
HKD1_k127_5355203_18 TPR Domain containing protein - - - 0.00000003294 65.0
HKD1_k127_5355203_19 - - - - 0.0000004479 58.0
HKD1_k127_5355203_2 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 507.0
HKD1_k127_5355203_21 OstA-like protein K09774 - - 0.0004376 53.0
HKD1_k127_5355203_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 346.0
HKD1_k127_5355203_4 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 330.0
HKD1_k127_5355203_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 314.0
HKD1_k127_5355203_6 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 297.0
HKD1_k127_5355203_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 284.0
HKD1_k127_5355203_8 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001707 227.0
HKD1_k127_5355203_9 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000004915 196.0
HKD1_k127_5362786_0 peptidyl-tyrosine sulfation - - - 0.0 1159.0
HKD1_k127_5362786_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 575.0
HKD1_k127_5362786_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
HKD1_k127_5362786_3 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 292.0
HKD1_k127_5362786_4 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000504 256.0
HKD1_k127_5362786_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000001762 180.0
HKD1_k127_5362786_6 Protein of unknown function, DUF393 - - - 0.000000000000000002769 98.0
HKD1_k127_5362786_7 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000001707 71.0
HKD1_k127_5373674_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.382e-270 856.0
HKD1_k127_5373674_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
HKD1_k127_5373674_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 391.0
HKD1_k127_5373674_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000001017 113.0
HKD1_k127_5373674_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00007137 51.0
HKD1_k127_5378493_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 409.0
HKD1_k127_5378493_1 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 313.0
HKD1_k127_5378493_2 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000006758 175.0
HKD1_k127_5378493_3 RNA methyltransferase RsmD family - - - 0.0000000000000000000000000001154 124.0
HKD1_k127_5378493_4 - - - - 0.000000000002017 76.0
HKD1_k127_5378493_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000005694 61.0
HKD1_k127_5402346_0 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 341.0
HKD1_k127_5402346_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000618 269.0
HKD1_k127_5402346_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000002865 121.0
HKD1_k127_5402346_3 Polymer-forming cytoskeletal - - - 0.0000001462 62.0
HKD1_k127_5424583_0 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007815 253.0
HKD1_k127_5424583_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002507 257.0
HKD1_k127_5424583_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000002448 123.0
HKD1_k127_5424583_3 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.000000008931 63.0
HKD1_k127_5424583_4 General secretion pathway protein K02459 - - 0.00002707 55.0
HKD1_k127_5427995_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 426.0
HKD1_k127_5427995_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 342.0
HKD1_k127_5427995_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000006812 211.0
HKD1_k127_5427995_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 0.000005797 56.0
HKD1_k127_5467743_0 Protein of unknown function (DUF1587) - - - 3.732e-237 759.0
HKD1_k127_5467743_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 531.0
HKD1_k127_5467743_2 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000002616 105.0
HKD1_k127_5467743_3 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000001055 100.0
HKD1_k127_5482805_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000001366 230.0
HKD1_k127_5482805_1 ACT domain - - - 0.000000000000000000000000000000000000000000000005737 177.0
HKD1_k127_5482805_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.000000000004695 67.0
HKD1_k127_5496981_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000013 225.0
HKD1_k127_5496981_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
HKD1_k127_5496981_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000008846 167.0
HKD1_k127_5496981_3 Glutaredoxin K07390 - - 0.000000000000000000000000000000000000000001006 159.0
HKD1_k127_5496981_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000006141 156.0
HKD1_k127_5496981_5 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000344 154.0
HKD1_k127_5496981_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.0000000000000000000005335 99.0
HKD1_k127_5498928_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 482.0
HKD1_k127_5498928_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 371.0
HKD1_k127_5498928_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 360.0
HKD1_k127_5498928_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 340.0
HKD1_k127_5498928_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000097 286.0
HKD1_k127_5498928_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000009645 211.0
HKD1_k127_5498928_6 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000007273 160.0
HKD1_k127_5498928_7 Thioesterase superfamily - - - 0.00000000000000000000000000001081 124.0
HKD1_k127_5498928_8 Protein conserved in bacteria - - - 0.00000000000000000000000002116 122.0
HKD1_k127_5498928_9 PFAM Protein kinase domain - - - 0.00000002276 66.0
HKD1_k127_5503404_0 DEAD DEAH box helicase K03724 - - 0.0 1612.0
HKD1_k127_5503404_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
HKD1_k127_5503404_2 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003714 264.0
HKD1_k127_5503404_3 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000004062 190.0
HKD1_k127_5503404_4 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000001238 192.0
HKD1_k127_5503404_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000006934 168.0
HKD1_k127_5503404_6 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000002924 169.0
HKD1_k127_5503404_7 Histidine kinase - - - 0.000000000000000000000000000000000815 146.0
HKD1_k127_5503404_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000003718 104.0
HKD1_k127_5503404_9 RNA polymerase activity K03060 - 2.7.7.6 0.00000001675 61.0
HKD1_k127_5525369_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1201.0
HKD1_k127_5525369_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000006005 228.0
HKD1_k127_5525369_2 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000000000000000000000000002717 198.0
HKD1_k127_5525369_3 cheY-homologous receiver domain - - - 0.00000000000000000000000002374 113.0
HKD1_k127_5525369_4 Domain of unknown function (DUF5069) - - - 0.000000000000000009947 88.0
HKD1_k127_5525369_5 Domain of unknown function (DUF5069) - - - 0.0000000000000001138 85.0
HKD1_k127_5525369_6 lipolytic protein G-D-S-L family - - - 0.000000000000001175 76.0
HKD1_k127_5525369_7 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000001631 65.0
HKD1_k127_5525369_8 Lipopolysaccharide-assembly - - - 0.00000005086 61.0
HKD1_k127_5525369_9 nuclear chromosome segregation - - - 0.0001933 51.0
HKD1_k127_5534344_0 DUF218 domain - - - 0.00000000000000000000000000000000000000000000009477 179.0
HKD1_k127_5534344_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000009552 117.0
HKD1_k127_5534344_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000001803 81.0
HKD1_k127_5534344_3 endonuclease exonuclease phosphatase K07004 - - 0.000000000005462 75.0
HKD1_k127_5534344_4 Glycosyl transferases group 1 - - - 0.0000006275 54.0
HKD1_k127_5539695_0 Large extracellular alpha-helical protein K06894 - - 2.983e-306 1006.0
HKD1_k127_5539695_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 331.0
HKD1_k127_5539695_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001044 234.0
HKD1_k127_5539695_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000006091 193.0
HKD1_k127_5620378_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.064e-291 903.0
HKD1_k127_5620378_1 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000004609 219.0
HKD1_k127_5682364_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 646.0
HKD1_k127_5682364_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 505.0
HKD1_k127_5682364_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000001438 138.0
HKD1_k127_5682364_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.00000000000000000000000000291 124.0
HKD1_k127_5682364_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000001502 102.0
HKD1_k127_5682364_5 - - - - 0.00000000000009512 78.0
HKD1_k127_5682364_6 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000002018 53.0
HKD1_k127_5682364_7 NHL repeat containing protein - - - 0.0003852 45.0
HKD1_k127_5701289_0 Sugar (and other) transporter K08178 - - 1.746e-194 617.0
HKD1_k127_5701289_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 521.0
HKD1_k127_5701289_10 Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000001025 260.0
HKD1_k127_5701289_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000006359 246.0
HKD1_k127_5701289_12 Glycosyl transferase, family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000004281 234.0
HKD1_k127_5701289_13 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
HKD1_k127_5701289_14 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000001784 188.0
HKD1_k127_5701289_15 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000008134 171.0
HKD1_k127_5701289_16 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000001179 147.0
HKD1_k127_5701289_17 ACT domain - - - 0.000000000000000000000000000000000002933 142.0
HKD1_k127_5701289_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000001647 139.0
HKD1_k127_5701289_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000003238 120.0
HKD1_k127_5701289_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 520.0
HKD1_k127_5701289_20 - - - - 0.000000000000000000000000006398 122.0
HKD1_k127_5701289_21 50S ribosomal protein L31 K02909 - - 0.0000000000000000000001198 99.0
HKD1_k127_5701289_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 481.0
HKD1_k127_5701289_4 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 449.0
HKD1_k127_5701289_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 426.0
HKD1_k127_5701289_6 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 305.0
HKD1_k127_5701289_7 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 307.0
HKD1_k127_5701289_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
HKD1_k127_5701289_9 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000178 287.0
HKD1_k127_5738565_0 Peptidase U32 K08303 - - 0.0 1162.0
HKD1_k127_5738565_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 9.17e-232 753.0
HKD1_k127_5738565_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000004749 243.0
HKD1_k127_5738565_11 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001579 211.0
HKD1_k127_5738565_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000001762 203.0
HKD1_k127_5738565_13 NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000002055 199.0
HKD1_k127_5738565_14 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000002314 162.0
HKD1_k127_5738565_15 S-layer homology domain - - - 0.00000000000007088 85.0
HKD1_k127_5738565_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 531.0
HKD1_k127_5738565_3 COG0464 ATPases of the AAA class - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 479.0
HKD1_k127_5738565_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 415.0
HKD1_k127_5738565_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 325.0
HKD1_k127_5738565_6 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 307.0
HKD1_k127_5738565_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000104 269.0
HKD1_k127_5738565_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 258.0
HKD1_k127_5738565_9 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 261.0
HKD1_k127_57829_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation - - - 6.209e-256 805.0
HKD1_k127_57829_1 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 385.0
HKD1_k127_57829_2 Domain of unknown function (DUF4956) - - - 0.000000000000000000000006536 110.0
HKD1_k127_57829_3 COG5036 SPX domain-containing protein involved in vacuolar polyphosphate accumulation - - - 0.0000000000000003741 88.0
HKD1_k127_57829_4 ABC transporter component K02005 - - 0.000000002309 69.0
HKD1_k127_581610_0 von Willebrand factor, type A K07114 - - 1.688e-200 649.0
HKD1_k127_581610_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 418.0
HKD1_k127_581610_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
HKD1_k127_581610_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000002891 180.0
HKD1_k127_581610_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000007297 165.0
HKD1_k127_581610_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000005529 114.0
HKD1_k127_581610_7 LysE type translocator K06895 - - 0.00006739 53.0
HKD1_k127_5920347_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.229e-268 842.0
HKD1_k127_5920347_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 539.0
HKD1_k127_5920347_2 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 364.0
HKD1_k127_5920347_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 295.0
HKD1_k127_5920347_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
HKD1_k127_5920347_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000003355 159.0
HKD1_k127_5920347_6 - - - - 0.000000000000000001471 90.0
HKD1_k127_5920347_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000006836 74.0
HKD1_k127_6007760_0 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 439.0
HKD1_k127_6007760_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 355.0
HKD1_k127_6007760_2 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HKD1_k127_6007760_3 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005592 255.0
HKD1_k127_6033931_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1230.0
HKD1_k127_6033931_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 2.462e-196 615.0
HKD1_k127_6033931_10 Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 339.0
HKD1_k127_6033931_11 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 310.0
HKD1_k127_6033931_12 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001368 257.0
HKD1_k127_6033931_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
HKD1_k127_6033931_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000166 232.0
HKD1_k127_6033931_15 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD1_k127_6033931_16 - - - - 0.00000000000000000000000000000000000000000000000001944 183.0
HKD1_k127_6033931_17 ECF sigma factor - - - 0.0000000000000000000000000000000000000000001032 170.0
HKD1_k127_6033931_18 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000003239 151.0
HKD1_k127_6033931_19 - - - - 0.0000000002066 69.0
HKD1_k127_6033931_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 6.357e-195 628.0
HKD1_k127_6033931_20 Tetratricopeptide repeat - - - 0.0006514 50.0
HKD1_k127_6033931_3 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 582.0
HKD1_k127_6033931_4 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 500.0
HKD1_k127_6033931_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 484.0
HKD1_k127_6033931_6 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 472.0
HKD1_k127_6033931_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 473.0
HKD1_k127_6033931_8 methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 442.0
HKD1_k127_6033931_9 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 387.0
HKD1_k127_6060169_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 598.0
HKD1_k127_6060169_1 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 518.0
HKD1_k127_6060169_10 mechanosensitive ion channel K22044 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001089 185.0
HKD1_k127_6060169_11 Rhomboid family - - - 0.0000000000000000000000000000004421 134.0
HKD1_k127_6060169_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000001748 113.0
HKD1_k127_6060169_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000004108 104.0
HKD1_k127_6060169_14 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.00000000000000000009223 96.0
HKD1_k127_6060169_15 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000003559 93.0
HKD1_k127_6060169_16 - - - - 0.000000000000001769 77.0
HKD1_k127_6060169_17 Src homology 3 domains - - - 0.000000003026 68.0
HKD1_k127_6060169_18 PFAM LysM domain - - - 0.000004062 59.0
HKD1_k127_6060169_19 Universal stress protein - - - 0.0001073 46.0
HKD1_k127_6060169_2 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 488.0
HKD1_k127_6060169_20 dehydrogenase - - - 0.000215 44.0
HKD1_k127_6060169_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 392.0
HKD1_k127_6060169_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 328.0
HKD1_k127_6060169_5 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000212 272.0
HKD1_k127_6060169_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
HKD1_k127_6060169_7 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000002804 239.0
HKD1_k127_6060169_8 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000108 200.0
HKD1_k127_6060169_9 - - - - 0.0000000000000000000000000000000000000000000000002553 185.0
HKD1_k127_6073274_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 511.0
HKD1_k127_6073274_1 chorismate binding enzyme K01665,K03342,K13950 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000006321 137.0
HKD1_k127_6073274_2 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000002408 126.0
HKD1_k127_6105818_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 431.0
HKD1_k127_6105818_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 395.0
HKD1_k127_6105818_2 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000000000001302 205.0
HKD1_k127_6105818_3 - - - - 0.0000000000000000003194 89.0
HKD1_k127_6138101_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0 1927.0
HKD1_k127_6138101_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 449.0
HKD1_k127_6138101_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 381.0
HKD1_k127_6138101_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 370.0
HKD1_k127_6138101_4 Glycosyltransferase family 9 (heptosyltransferase) K02517,K02843 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000005061 264.0
HKD1_k127_6138101_5 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
HKD1_k127_6138101_6 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003878 239.0
HKD1_k127_6138101_7 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000001461 122.0
HKD1_k127_6181805_0 Protein of unknown function (DUF1587) - - - 7.696e-215 695.0
HKD1_k127_6181805_1 56kDa selenium binding protein (SBP56) K17285 - - 1.131e-202 640.0
HKD1_k127_6181805_10 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000911 238.0
HKD1_k127_6181805_11 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000004427 228.0
HKD1_k127_6181805_12 membrane K08978 - - 0.000000000000000000000000000000000000000000000000000000006917 204.0
HKD1_k127_6181805_13 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000008276 198.0
HKD1_k127_6181805_14 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000005019 186.0
HKD1_k127_6181805_15 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000004385 158.0
HKD1_k127_6181805_16 Chromate resistance exported protein - - - 0.000000000000000000000007816 101.0
HKD1_k127_6181805_17 Protein of unknown function (DUF3455) - - - 0.00000000000000000002071 106.0
HKD1_k127_6181805_18 superoxide dismutase activity K02674,K04565 - 1.15.1.1 0.000000006351 66.0
HKD1_k127_6181805_2 ATPase associated with various cellular activities, AAA_5 K02584 - - 1.803e-200 643.0
HKD1_k127_6181805_3 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 489.0
HKD1_k127_6181805_4 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 421.0
HKD1_k127_6181805_5 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 373.0
HKD1_k127_6181805_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 339.0
HKD1_k127_6181805_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 330.0
HKD1_k127_6181805_8 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 330.0
HKD1_k127_6181805_9 pyrroloquinoline quinone binding K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004281 263.0
HKD1_k127_6190784_0 Fibronectin type III-like domain K05349 - 3.2.1.21 2.859e-271 859.0
HKD1_k127_6190784_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.183e-218 686.0
HKD1_k127_6190784_2 Major facilitator superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 476.0
HKD1_k127_6190784_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 403.0
HKD1_k127_6190784_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 310.0
HKD1_k127_6251899_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1032.0
HKD1_k127_6251899_1 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 5.473e-247 782.0
HKD1_k127_6251899_10 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 289.0
HKD1_k127_6251899_11 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000005073 225.0
HKD1_k127_6251899_12 HAF family - - - 0.0000000000000000000000000000000000000000000000000000000000002977 239.0
HKD1_k127_6251899_13 - - - - 0.0000000000000000000000000000000000000000008815 169.0
HKD1_k127_6251899_14 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000003845 127.0
HKD1_k127_6251899_15 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000001346 88.0
HKD1_k127_6251899_16 Domain of unknown function (DUF4339) - - - 0.00000003706 66.0
HKD1_k127_6251899_17 - - - - 0.00000008546 65.0
HKD1_k127_6251899_2 Voltage gated chloride channel - - - 1.007e-243 767.0
HKD1_k127_6251899_3 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 544.0
HKD1_k127_6251899_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 527.0
HKD1_k127_6251899_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 516.0
HKD1_k127_6251899_6 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 443.0
HKD1_k127_6251899_7 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 423.0
HKD1_k127_6251899_8 Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 348.0
HKD1_k127_6251899_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 303.0
HKD1_k127_6256744_0 Pyrimidine nucleoside phosphorylase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 376.0
HKD1_k127_6256744_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000008013 211.0
HKD1_k127_6256744_2 haemagglutination activity domain - - - 0.0000000000000000000000000000000000004117 164.0
HKD1_k127_6256744_3 DNA-templated transcription, initiation - - - 0.00000000000000000000000000007752 125.0
HKD1_k127_6256744_4 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000002441 101.0
HKD1_k127_6256744_5 Hemin-binding protein - - - 0.00000000000000009829 92.0
HKD1_k127_6267741_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 480.0
HKD1_k127_6267741_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K05587 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
HKD1_k127_6267741_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 334.0
HKD1_k127_6267741_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000123 286.0
HKD1_k127_6267741_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001066 237.0
HKD1_k127_6267741_5 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000443 203.0
HKD1_k127_6274489_0 Phosphoglucose isomerase K01810 - 5.3.1.9 4.768e-288 892.0
HKD1_k127_6274489_1 Arginosuccinate synthase K01940 - 6.3.4.5 6.837e-215 683.0
HKD1_k127_6274489_10 Protein of unknown function (DUF1326) - - - 0.0000001605 62.0
HKD1_k127_6274489_2 Bacterial regulatory protein, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 557.0
HKD1_k127_6274489_3 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 463.0
HKD1_k127_6274489_4 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
HKD1_k127_6274489_5 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009014 263.0
HKD1_k127_6274489_6 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000002859 208.0
HKD1_k127_6274489_7 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000002346 145.0
HKD1_k127_6274489_8 Protein of unknown function (DUF1559) - - - 0.000000000000000000000000000000007002 136.0
HKD1_k127_6274489_9 - - - - 0.00000000000000002667 91.0
HKD1_k127_6279626_0 transcription factor binding K15836 - - 1.597e-215 687.0
HKD1_k127_6279626_1 gluconolactonase activity K01053 - 3.1.1.17 1.201e-198 632.0
HKD1_k127_6279626_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 374.0
HKD1_k127_6279626_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 308.0
HKD1_k127_6279626_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000154 158.0
HKD1_k127_6279626_5 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000431 139.0
HKD1_k127_6279626_6 YHS domain protein - - - 0.00000000000000000000000000002303 129.0
HKD1_k127_6279626_7 YHS domain - - - 0.0000000000000000000000000006599 125.0
HKD1_k127_6279626_8 - - - - 0.00000000000000000000000002143 117.0
HKD1_k127_6279626_9 - - - - 0.000000000000004739 80.0
HKD1_k127_6312095_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 598.0
HKD1_k127_6312095_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 410.0
HKD1_k127_6312095_2 aromatic amino acid beta-eliminating lyase threonine aldolase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 363.0
HKD1_k127_6312095_3 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
HKD1_k127_6312095_4 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 0.000000000000000001158 101.0
HKD1_k127_631396_0 NAD synthase - - - 2.653e-202 643.0
HKD1_k127_631396_1 Oxidoreductase NAD-binding domain K00380 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 591.0
HKD1_k127_631396_2 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 506.0
HKD1_k127_631396_3 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
HKD1_k127_631396_4 NMT1-like family K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006997 287.0
HKD1_k127_631396_5 - - - - 0.00000000000000000000000000000000000000000000000000000000003576 216.0
HKD1_k127_631396_6 TM2 domain - - - 0.00000000000000000000000000001947 121.0
HKD1_k127_631396_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000082 100.0
HKD1_k127_631396_8 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0004132 43.0
HKD1_k127_6364728_0 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 486.0
HKD1_k127_6364728_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 431.0
HKD1_k127_6364728_10 Domain of unknown function (DUF4266) - - - 0.000000000000003028 81.0
HKD1_k127_6364728_2 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 355.0
HKD1_k127_6364728_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 339.0
HKD1_k127_6364728_4 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000003127 187.0
HKD1_k127_6364728_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000006434 140.0
HKD1_k127_6364728_6 Thioredoxin - - - 0.000000000000000000000000000001737 129.0
HKD1_k127_6364728_7 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000002687 104.0
HKD1_k127_6364728_8 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000000005378 115.0
HKD1_k127_6364728_9 Carbohydrate family 9 binding domain-like - - - 0.000000000000000003987 94.0
HKD1_k127_6371382_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 1.432e-237 749.0
HKD1_k127_6371382_1 B12 binding domain - - - 5.963e-194 617.0
HKD1_k127_6371382_10 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
HKD1_k127_6371382_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 302.0
HKD1_k127_6371382_12 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001562 268.0
HKD1_k127_6371382_13 AAA ATPase central domain protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001111 252.0
HKD1_k127_6371382_14 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000001915 214.0
HKD1_k127_6371382_15 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000002191 220.0
HKD1_k127_6371382_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000003518 188.0
HKD1_k127_6371382_17 Putative methyltransferase - - - 0.0000000000000000000000000000000000000004401 173.0
HKD1_k127_6371382_18 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000001918 157.0
HKD1_k127_6371382_19 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000000000000000000000000000007761 142.0
HKD1_k127_6371382_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 550.0
HKD1_k127_6371382_20 - - - - 0.0000000000000000000000000000004483 133.0
HKD1_k127_6371382_21 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000003759 95.0
HKD1_k127_6371382_22 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000008124 85.0
HKD1_k127_6371382_23 Phosphoethanolamine methyltransferase K05929 - 2.1.1.103 0.0000003904 61.0
HKD1_k127_6371382_24 (ABC) transporter K06147 - - 0.00000152 50.0
HKD1_k127_6371382_25 general secretion pathway protein K02456 - - 0.0001226 49.0
HKD1_k127_6371382_26 Bacterial protein of unknown function (DUF883) - GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0043021,GO:0043024,GO:0044464,GO:0044877,GO:0060187,GO:0071944 - 0.0005723 46.0
HKD1_k127_6371382_27 - - - - 0.0008097 47.0
HKD1_k127_6371382_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 528.0
HKD1_k127_6371382_4 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 514.0
HKD1_k127_6371382_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 481.0
HKD1_k127_6371382_6 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 466.0
HKD1_k127_6371382_7 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 400.0
HKD1_k127_6371382_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 370.0
HKD1_k127_6371382_9 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
HKD1_k127_637828_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.482e-223 700.0
HKD1_k127_637828_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 470.0
HKD1_k127_637828_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
HKD1_k127_637828_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 390.0
HKD1_k127_637828_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 372.0
HKD1_k127_637828_5 Glycosyl hydrolase family 62 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
HKD1_k127_637828_6 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004287 285.0
HKD1_k127_637828_7 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000006568 189.0
HKD1_k127_637828_8 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000000000000000000003874 175.0
HKD1_k127_637828_9 BlaR1 peptidase M56 - - - 0.0003245 49.0
HKD1_k127_6388421_0 prohibitin homologues K07192 - - 2.296e-263 822.0
HKD1_k127_6388421_1 Protein of unknown function, DUF255 K06888 - - 3.229e-205 660.0
HKD1_k127_6388421_10 Planctomycete cytochrome C - - - 0.000000000000000000000002097 107.0
HKD1_k127_6388421_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000001386 91.0
HKD1_k127_6388421_12 - - - - 0.00000000000000003007 83.0
HKD1_k127_6388421_13 CAAX protease self-immunity K07052 - - 0.00000000000003001 83.0
HKD1_k127_6388421_14 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.0000000000001768 75.0
HKD1_k127_6388421_15 Phospholipase_D-nuclease N-terminal - - - 0.000000005835 61.0
HKD1_k127_6388421_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 433.0
HKD1_k127_6388421_3 lipolytic protein G-D-S-L family K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 442.0
HKD1_k127_6388421_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003274 257.0
HKD1_k127_6388421_6 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
HKD1_k127_6388421_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000006539 244.0
HKD1_k127_6388421_8 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000001712 140.0
HKD1_k127_6388421_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000001711 119.0
HKD1_k127_6429158_0 BlaR1 peptidase M56 K02172 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
HKD1_k127_6429158_1 Psort location Extracellular, score - - - 0.00000000000000000000000000000000000000000000000000001556 202.0
HKD1_k127_6429158_2 Penicillinase repressor K02171 - - 0.00000000000000000000000000000000000000000003278 164.0
HKD1_k127_6429158_3 - - - - 0.00004365 55.0
HKD1_k127_6435787_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 611.0
HKD1_k127_6435787_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000007347 138.0
HKD1_k127_6435787_2 MobA-like NTP transferase domain - - - 0.000000000000000000000000000005656 126.0
HKD1_k127_6435787_3 Protein of unknown function (Gmx_para_CXXCG) - - - 0.000000000000000000000004667 113.0
HKD1_k127_6435787_4 sequence-specific DNA binding K02854,K02855 - - 0.0000000007143 70.0
HKD1_k127_6453648_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1405.0
HKD1_k127_6453648_1 PFAM Dockerin type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 498.0
HKD1_k127_6453648_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 383.0
HKD1_k127_6453648_3 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 313.0
HKD1_k127_6453648_4 CotH kinase protein - - - 0.000000000000000000000000000000000001238 153.0
HKD1_k127_6453648_5 Methyltransferase K00587 - 2.1.1.100 0.000000000000000000000000000000000004843 145.0
HKD1_k127_6453648_6 - - - - 0.000000000000000000000000000000002139 138.0
HKD1_k127_6453648_7 general secretion pathway protein G K02456 - - 0.0000000000000000000000000003042 120.0
HKD1_k127_6453648_8 PFAM Protein kinase domain K08309 - - 0.0000000000000000000001338 107.0
HKD1_k127_6453648_9 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000002376 79.0
HKD1_k127_6468786_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.364e-268 837.0
HKD1_k127_6468786_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 1.499e-210 667.0
HKD1_k127_6468786_10 Poly3-Hydroxybutyrate Depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 306.0
HKD1_k127_6468786_11 Formyl transferase K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000005737 265.0
HKD1_k127_6468786_12 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005518 261.0
HKD1_k127_6468786_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000003214 231.0
HKD1_k127_6468786_14 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000004043 224.0
HKD1_k127_6468786_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000005278 220.0
HKD1_k127_6468786_16 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000009622 194.0
HKD1_k127_6468786_17 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000002241 194.0
HKD1_k127_6468786_18 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000002535 200.0
HKD1_k127_6468786_19 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000000000000002037 177.0
HKD1_k127_6468786_2 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 608.0
HKD1_k127_6468786_20 Protein of unknown function (DUF2959) - - - 0.0000000000000000000000000000000000000000000008093 176.0
HKD1_k127_6468786_21 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000001403 170.0
HKD1_k127_6468786_22 NUDIX domain - - - 0.00000000000000000000000000000000000000001354 162.0
HKD1_k127_6468786_23 Protein conserved in bacteria - - - 0.00000000000000000000000164 107.0
HKD1_k127_6468786_24 - - - - 0.0000000000000000157 85.0
HKD1_k127_6468786_25 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000002618 90.0
HKD1_k127_6468786_26 AAA domain K02282 - - 0.0000000000000003276 84.0
HKD1_k127_6468786_27 - K20543 - - 0.0000000000000003729 85.0
HKD1_k127_6468786_28 Protein of unknown function (DUF3185) - - - 0.00000000000002643 75.0
HKD1_k127_6468786_29 BON domain - - - 0.0000000000005198 76.0
HKD1_k127_6468786_3 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 599.0
HKD1_k127_6468786_30 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000002004 72.0
HKD1_k127_6468786_31 PFAM Major Facilitator Superfamily - - - 0.00004608 55.0
HKD1_k127_6468786_32 (FHA) domain - - - 0.000308 49.0
HKD1_k127_6468786_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 512.0
HKD1_k127_6468786_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 502.0
HKD1_k127_6468786_6 Na dependent nucleoside transporter domain protein K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 495.0
HKD1_k127_6468786_7 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 400.0
HKD1_k127_6468786_8 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 349.0
HKD1_k127_6468786_9 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
HKD1_k127_6469101_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 8.323e-206 648.0
HKD1_k127_6469101_1 Aminotransferase class I and II - - - 1.537e-199 638.0
HKD1_k127_6469101_10 PFAM type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000522 171.0
HKD1_k127_6469101_11 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000002755 155.0
HKD1_k127_6469101_12 Thioredoxin K03671 - - 0.0000000000000000000000000000000000007648 142.0
HKD1_k127_6469101_13 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000001048 121.0
HKD1_k127_6469101_14 Type II secretion system (T2SS), protein F - - - 0.00000000000000000000000009157 119.0
HKD1_k127_6469101_15 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000001553 109.0
HKD1_k127_6469101_16 Type IV pilus assembly protein PilM K02662 - - 0.000000000001804 79.0
HKD1_k127_6469101_17 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.00000002267 61.0
HKD1_k127_6469101_2 FAD linked oxidase - - - 1.375e-195 622.0
HKD1_k127_6469101_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 519.0
HKD1_k127_6469101_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 364.0
HKD1_k127_6469101_5 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001921 263.0
HKD1_k127_6469101_6 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002751 238.0
HKD1_k127_6469101_7 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000001517 201.0
HKD1_k127_6469101_8 Helix-turn-helix diphteria tox regulatory element K11924 - - 0.00000000000000000000000000000000000000000000000373 177.0
HKD1_k127_6469101_9 - - - - 0.000000000000000000000000000000000000000000001711 166.0
HKD1_k127_6618328_0 E1-E2 ATPase K12949,K12956,K17686 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 501.0
HKD1_k127_6618328_1 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
HKD1_k127_6618328_2 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000002434 185.0
HKD1_k127_6618328_3 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.000000000000000000000000003313 118.0
HKD1_k127_6618328_4 CHAD domain - - - 0.00000000000002267 83.0
HKD1_k127_6644244_0 NMT1-like family - - - 2.096e-207 656.0
HKD1_k127_6644244_1 AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 551.0
HKD1_k127_6644244_2 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
HKD1_k127_6644244_3 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 420.0
HKD1_k127_6644244_4 NMT1-like family K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 403.0
HKD1_k127_6644244_5 Binding-protein-dependent transport system inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 382.0
HKD1_k127_6644244_6 aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
HKD1_k127_6644244_7 ABC transporter K02049,K15578,K15579 - - 0.00000000000000000000000000000000007517 134.0
HKD1_k127_6644244_8 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000004958 121.0
HKD1_k127_6644244_9 Phage-related minor tail protein - - - 0.000000005761 66.0
HKD1_k127_6666678_0 Bacterial alpha-L-rhamnosidase concanavalin-like domain K05989 - 3.2.1.40 1.587e-260 829.0
HKD1_k127_6666678_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 543.0
HKD1_k127_6666678_2 COGs COG2382 Enterochelin esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 517.0
HKD1_k127_6666678_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 251.0
HKD1_k127_6666678_4 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000002115 167.0
HKD1_k127_6666678_5 Outer membrane protein beta-barrel domain - - - 0.00001496 56.0
HKD1_k127_6678433_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 603.0
HKD1_k127_6678433_1 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 379.0
HKD1_k127_6678433_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 370.0
HKD1_k127_6678433_3 PFAM von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 351.0
HKD1_k127_6678433_4 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 296.0
HKD1_k127_6678433_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 290.0
HKD1_k127_6678433_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007458 267.0
HKD1_k127_6678433_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000004244 209.0
HKD1_k127_6678433_8 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20444 - 2.1.1.79 0.000000000000000000000000000000000000000001644 164.0
HKD1_k127_6678433_9 - - - - 0.000000000000000000001676 102.0
HKD1_k127_669021_0 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 552.0
HKD1_k127_669021_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 421.0
HKD1_k127_669021_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 422.0
HKD1_k127_669021_3 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 305.0
HKD1_k127_669021_4 Response regulator receiver - - - 0.00000000000000000000000000000000000001195 149.0
HKD1_k127_669021_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000002142 68.0
HKD1_k127_669021_6 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000002354 62.0
HKD1_k127_669021_7 PIN domain - - - 0.00008506 49.0
HKD1_k127_6728897_0 PFAM Asparagine synthase K01953 - 6.3.5.4 2.508e-223 711.0
HKD1_k127_6728897_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 578.0
HKD1_k127_6728897_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000002488 191.0
HKD1_k127_6728897_11 lipolytic protein G-D-S-L family K01218 - 3.2.1.78 0.000000000000000000000000000000000000006491 155.0
HKD1_k127_6728897_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000001208 129.0
HKD1_k127_6728897_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000003699 122.0
HKD1_k127_6728897_14 Membrane bound O-acyl transferase family - - - 0.000000000000000001686 98.0
HKD1_k127_6728897_15 - - - - 0.0000000001638 68.0
HKD1_k127_6728897_16 transferase activity, transferring glycosyl groups - - - 0.0000000001863 61.0
HKD1_k127_6728897_17 transferase activity, transferring glycosyl groups - - - 0.0000002889 53.0
HKD1_k127_6728897_18 Passenger-associated-transport-repeat - - - 0.0000159 57.0
HKD1_k127_6728897_2 threonine synthase activity K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 491.0
HKD1_k127_6728897_3 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 364.0
HKD1_k127_6728897_4 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 334.0
HKD1_k127_6728897_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 314.0
HKD1_k127_6728897_6 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 303.0
HKD1_k127_6728897_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 286.0
HKD1_k127_6728897_9 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000006013 193.0
HKD1_k127_6832772_0 ATPases associated with a variety of cellular activities K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 401.0
HKD1_k127_6832772_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000004141 221.0
HKD1_k127_6832772_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000444 194.0
HKD1_k127_6832772_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000003198 155.0
HKD1_k127_6832772_4 - - - - 0.00000000000000000000000000000000000000004555 156.0
HKD1_k127_6832772_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000004924 137.0
HKD1_k127_6832772_6 Peptidase M48 K06013 - 3.4.24.84 0.00000001377 61.0
HKD1_k127_6852450_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 596.0
HKD1_k127_6852450_1 gtp cyclohydrolase K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 306.0
HKD1_k127_6852450_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004779 247.0
HKD1_k127_6852450_3 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000007158 220.0
HKD1_k127_6852450_4 Putative regulatory protein - - - 0.0000000000000000000000000000003682 128.0
HKD1_k127_6852450_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000001579 123.0
HKD1_k127_6852450_6 domain, Protein K07654 - 2.7.13.3 0.00000000000000000000001716 114.0
HKD1_k127_688125_0 C-methyltransferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 492.0
HKD1_k127_688125_1 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 405.0
HKD1_k127_688125_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 353.0
HKD1_k127_688125_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HKD1_k127_688125_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000613 229.0
HKD1_k127_688125_5 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
HKD1_k127_688125_6 ADP-glyceromanno-heptose 6-epimerase activity K19180 - 1.1.1.339 0.000000000000000000000000000000000000000000000000000000494 205.0
HKD1_k127_688125_7 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000005667 131.0
HKD1_k127_688125_8 methyltransferase - - - 0.00000000000007101 74.0
HKD1_k127_688125_9 UbiE COQ5 - - - 0.00001025 51.0
HKD1_k127_6920918_0 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 4.38e-272 849.0
HKD1_k127_6920918_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 332.0
HKD1_k127_6920918_2 protease - - - 0.00000000000000000000000000000000000000000000000000000000000172 219.0
HKD1_k127_6920918_3 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000003502 199.0
HKD1_k127_6920918_4 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000006955 196.0
HKD1_k127_6943193_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1146.0
HKD1_k127_6943193_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1106.0
HKD1_k127_6943193_2 Pfam:PNPOx_C K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002219 257.0
HKD1_k127_6943193_3 cheY-homologous receiver domain - - - 0.000000000000000000000003061 110.0
HKD1_k127_6943193_4 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000002849 107.0
HKD1_k127_6943193_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.000000000000000151 82.0
HKD1_k127_6943937_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 563.0
HKD1_k127_6943937_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 449.0
HKD1_k127_6943937_2 - - - - 0.00000004857 57.0
HKD1_k127_6966511_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 340.0
HKD1_k127_6966511_1 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
HKD1_k127_6966511_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000002914 220.0
HKD1_k127_6966511_3 - - - - 0.000000000000000000000000000000000000000000000002185 179.0
HKD1_k127_6966511_4 general secretion pathway protein K02456 - - 0.0000000183 65.0
HKD1_k127_6979556_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 462.0
HKD1_k127_6979556_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 460.0
HKD1_k127_6979556_10 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000002171 76.0
HKD1_k127_6979556_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 380.0
HKD1_k127_6979556_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 297.0
HKD1_k127_6979556_4 Binding-protein-dependent transport system inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002136 286.0
HKD1_k127_6979556_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
HKD1_k127_6979556_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000002873 231.0
HKD1_k127_6979556_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001274 229.0
HKD1_k127_6979556_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000009578 139.0
HKD1_k127_6979556_9 Methyltransferase FkbM domain - - - 0.0000000000000007574 89.0
HKD1_k127_7005101_0 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 367.0
HKD1_k127_7005101_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006504 273.0
HKD1_k127_7005101_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 251.0
HKD1_k127_7005101_3 Tetratricopeptide repeat - - - 0.00000000000000000001018 97.0
HKD1_k127_7005101_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0002896 45.0
HKD1_k127_7093407_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 339.0
HKD1_k127_7093407_1 PFAM YD repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001558 238.0
HKD1_k127_7093407_2 Protein of unknown function (DUF2851) - - - 0.0000000000000000000000000000000000000000000000000000000000004799 229.0
HKD1_k127_7093407_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000007802 194.0
HKD1_k127_7093407_4 RbsD / FucU transport protein family K06726 - 5.4.99.62 0.00000000000000000000000000000000000000000001825 164.0
HKD1_k127_7093407_5 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000004295 160.0
HKD1_k127_7093407_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000005844 147.0
HKD1_k127_7093407_7 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000005464 123.0
HKD1_k127_7093407_8 AsmA-like C-terminal region - - - 0.000000000000000000003403 110.0
HKD1_k127_7093407_9 Domain of unknown function (DUF4340) - - - 0.000000000000000006426 98.0
HKD1_k127_7095019_0 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.000000000000000000000000000000000000000000000000000001435 205.0
HKD1_k127_7095019_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000001048 203.0
HKD1_k127_7095019_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000003736 115.0
HKD1_k127_7095019_3 Belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.000000000000000000003551 100.0
HKD1_k127_7095019_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000003254 96.0
HKD1_k127_7095019_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000005747 72.0
HKD1_k127_7095019_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000125 68.0
HKD1_k127_7101659_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 558.0
HKD1_k127_7101659_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 378.0
HKD1_k127_7101659_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
HKD1_k127_7101659_3 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000003926 120.0
HKD1_k127_7101659_5 Permease YjgP YjgQ K11720 - - 0.0000000000000000000005071 108.0
HKD1_k127_7101659_6 Putative regulatory protein - - - 0.00000008369 57.0
HKD1_k127_7108852_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 426.0
HKD1_k127_7108852_1 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 314.0
HKD1_k127_7108852_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000001943 49.0
HKD1_k127_7132956_0 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 522.0
HKD1_k127_7132956_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 407.0
HKD1_k127_7132956_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001792 236.0
HKD1_k127_7132956_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000006177 196.0
HKD1_k127_7132956_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000001196 145.0
HKD1_k127_7135396_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1503.0
HKD1_k127_7135396_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 360.0
HKD1_k127_7135396_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000001547 81.0
HKD1_k127_7135396_3 Prokaryotic N-terminal methylation motif - - - 0.00000000001632 76.0
HKD1_k127_7135396_4 general secretion pathway protein K02456 - - 0.0001206 52.0
HKD1_k127_7145064_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.485e-240 775.0
HKD1_k127_7145064_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 7.249e-205 647.0
HKD1_k127_7145064_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 430.0
HKD1_k127_7145064_3 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 359.0
HKD1_k127_7145064_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 359.0
HKD1_k127_7145064_5 isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
HKD1_k127_7145064_6 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 283.0
HKD1_k127_7145064_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000001837 246.0
HKD1_k127_7145064_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000004007 236.0
HKD1_k127_7145064_9 protein conserved in bacteria - - - 0.00000000005502 68.0
HKD1_k127_7162875_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 500.0
HKD1_k127_7162875_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 480.0
HKD1_k127_7162875_10 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000006789 267.0
HKD1_k127_7162875_11 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000005704 239.0
HKD1_k127_7162875_12 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000002313 229.0
HKD1_k127_7162875_13 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
HKD1_k127_7162875_14 cheY-homologous receiver domain K02485 - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
HKD1_k127_7162875_15 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000003543 207.0
HKD1_k127_7162875_16 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000002464 205.0
HKD1_k127_7162875_17 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000003121 162.0
HKD1_k127_7162875_18 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000007361 160.0
HKD1_k127_7162875_19 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000001397 182.0
HKD1_k127_7162875_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 472.0
HKD1_k127_7162875_20 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000003899 155.0
HKD1_k127_7162875_21 Histidine kinase - - - 0.0000000000000000000000000000000000000002128 169.0
HKD1_k127_7162875_22 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000001596 123.0
HKD1_k127_7162875_23 FabA-like domain - - - 0.0000000000000000000000000001854 125.0
HKD1_k127_7162875_24 Phospholipid methyltransferase - - - 0.0000000000000000000009651 103.0
HKD1_k127_7162875_25 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000001502 99.0
HKD1_k127_7162875_26 - - - - 0.0000000000000000000243 98.0
HKD1_k127_7162875_27 - - - - 0.0000000000000002304 88.0
HKD1_k127_7162875_28 SpoIIAA-like - - - 0.0000000000000109 79.0
HKD1_k127_7162875_29 manually curated - - - 0.0000000000000313 77.0
HKD1_k127_7162875_3 Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 508.0
HKD1_k127_7162875_30 - - - - 0.0000000000409 65.0
HKD1_k127_7162875_31 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00001148 48.0
HKD1_k127_7162875_33 Bacterial protein of unknown function (DUF883) - - - 0.0004181 48.0
HKD1_k127_7162875_4 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 340.0
HKD1_k127_7162875_5 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 320.0
HKD1_k127_7162875_6 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 311.0
HKD1_k127_7162875_7 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 300.0
HKD1_k127_7162875_8 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 297.0
HKD1_k127_7162875_9 KR domain K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 290.0
HKD1_k127_7169402_0 pathogenesis K18286,K20276 - 3.5.4.40 0.0 1582.0
HKD1_k127_7169402_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.211e-217 691.0
HKD1_k127_7169402_10 PFAM response regulator receiver K13587 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000307 242.0
HKD1_k127_7169402_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005388 243.0
HKD1_k127_7169402_12 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000001108 182.0
HKD1_k127_7169402_13 DNA / pantothenate metabolism flavoprotein K21977 - 6.3.2.5 0.00000000000000000000000000000000000007491 150.0
HKD1_k127_7169402_14 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000008107 143.0
HKD1_k127_7169402_15 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000001891 129.0
HKD1_k127_7169402_16 cellulose binding - - - 0.0000000000000000003524 106.0
HKD1_k127_7169402_2 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 515.0
HKD1_k127_7169402_3 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 507.0
HKD1_k127_7169402_4 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 482.0
HKD1_k127_7169402_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
HKD1_k127_7169402_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 319.0
HKD1_k127_7169402_7 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
HKD1_k127_7169402_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002771 260.0
HKD1_k127_7169402_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002733 237.0
HKD1_k127_717247_0 Rhodanese Homology Domain K00529 - 1.18.1.3 3.631e-228 720.0
HKD1_k127_717247_1 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 353.0
HKD1_k127_717247_10 Putative zinc-finger - - - 0.000000000007552 68.0
HKD1_k127_717247_11 PFAM Integral membrane protein TerC K05794 - - 0.00000000003732 66.0
HKD1_k127_717247_12 His Kinase A (phosphoacceptor) domain K20971 - - 0.000001036 57.0
HKD1_k127_717247_13 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0004487 49.0
HKD1_k127_717247_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 309.0
HKD1_k127_717247_3 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002543 269.0
HKD1_k127_717247_4 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000008873 156.0
HKD1_k127_717247_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000006946 110.0
HKD1_k127_717247_6 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000004697 104.0
HKD1_k127_717247_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000003917 109.0
HKD1_k127_717247_8 Protein of unknown function (DUF2892) - - - 0.000000000000000000503 89.0
HKD1_k127_717247_9 domain protein - - - 0.000000000000000002865 89.0
HKD1_k127_7204380_0 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
HKD1_k127_7204380_1 galactokinase activity K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 309.0
HKD1_k127_7204380_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004592 283.0
HKD1_k127_7204380_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000209 216.0
HKD1_k127_7204380_4 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000004015 207.0
HKD1_k127_7204380_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000002417 193.0
HKD1_k127_7204380_6 Protein of unknown function (DUF1328) - - - 0.000000004814 60.0
HKD1_k127_7216982_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 474.0
HKD1_k127_7216982_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 408.0
HKD1_k127_7216982_2 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001076 267.0
HKD1_k127_7216982_3 RNA recognition motif - - - 0.0000000000000000000000000000006647 125.0
HKD1_k127_7216982_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000001057 110.0
HKD1_k127_7216982_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000006117 57.0
HKD1_k127_7234773_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 1.051e-243 759.0
HKD1_k127_7234773_1 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit K05587 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 466.0
HKD1_k127_7234773_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05588 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 350.0
HKD1_k127_7234773_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002403 263.0
HKD1_k127_7234773_4 - - - - 0.00000000000000000000000000000000000000000000001594 178.0
HKD1_k127_7241477_0 Transcriptional regulator K20968 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 455.0
HKD1_k127_7241477_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 412.0
HKD1_k127_7241477_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 364.0
HKD1_k127_7241477_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005534 260.0
HKD1_k127_7241477_4 S-layer homology domain - - - 0.000000000005552 74.0
HKD1_k127_7246713_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 299.0
HKD1_k127_7246713_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
HKD1_k127_7246713_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000005614 228.0
HKD1_k127_7246713_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000215 235.0
HKD1_k127_7246713_4 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000006998 205.0
HKD1_k127_7246713_5 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000008951 175.0
HKD1_k127_7246713_6 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000008586 163.0
HKD1_k127_7246713_7 Transcriptional regulator K02019 - - 0.000000000000000000000000006206 115.0
HKD1_k127_7246713_9 - - - - 0.0000000000001938 73.0
HKD1_k127_7270687_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 335.0
HKD1_k127_7270687_1 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007127 244.0
HKD1_k127_7270687_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000002275 230.0
HKD1_k127_7270687_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000001002 175.0
HKD1_k127_7270687_4 NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000002003 152.0
HKD1_k127_7270687_5 ubiE/COQ5 methyltransferase family - - - 0.00000000006263 72.0
HKD1_k127_727602_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.666e-247 779.0
HKD1_k127_727602_1 Cyclic nucleotide-monophosphate binding domain - - - 1.611e-212 679.0
HKD1_k127_727602_10 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 289.0
HKD1_k127_727602_11 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000002489 210.0
HKD1_k127_727602_12 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000001278 211.0
HKD1_k127_727602_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000001459 205.0
HKD1_k127_727602_14 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000001476 176.0
HKD1_k127_727602_15 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000001224 146.0
HKD1_k127_727602_16 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000001546 98.0
HKD1_k127_727602_17 Zinc ribbon domain - - - 0.000000000000000009972 87.0
HKD1_k127_727602_18 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000006382 83.0
HKD1_k127_727602_19 efflux transmembrane transporter activity K02004 - - 0.00006222 50.0
HKD1_k127_727602_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 565.0
HKD1_k127_727602_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 506.0
HKD1_k127_727602_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 430.0
HKD1_k127_727602_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 401.0
HKD1_k127_727602_6 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HKD1_k127_727602_7 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 348.0
HKD1_k127_727602_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 349.0
HKD1_k127_727602_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 329.0
HKD1_k127_7293601_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 437.0
HKD1_k127_7293601_1 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 422.0
HKD1_k127_7293601_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 323.0
HKD1_k127_7293601_4 Protein of unknown function (DUF721) - - - 0.00001422 53.0
HKD1_k127_7305693_0 Carbamoyltransferase C-terminus K00612 - - 1.602e-253 795.0
HKD1_k127_7305693_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 500.0
HKD1_k127_7305693_2 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 339.0
HKD1_k127_7305693_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
HKD1_k127_7305693_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000008373 142.0
HKD1_k127_7305693_5 - - - - 0.00000000007276 64.0
HKD1_k127_7305693_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000003932 62.0
HKD1_k127_7305693_8 - - - - 0.0000009533 56.0
HKD1_k127_7313205_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1375.0
HKD1_k127_7313205_1 TIGRFAM glycogen debranching enzyme - - - 2.663e-305 950.0
HKD1_k127_7313205_10 Surface antigen - - - 0.00000008492 63.0
HKD1_k127_7313205_2 Domain of unknown function (DUF3536) - - - 8.284e-294 922.0
HKD1_k127_7313205_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 9.141e-264 829.0
HKD1_k127_7313205_4 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.151e-257 809.0
HKD1_k127_7313205_5 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 2.342e-236 762.0
HKD1_k127_7313205_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 544.0
HKD1_k127_7313205_7 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 530.0
HKD1_k127_7313205_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003085 284.0
HKD1_k127_7313205_9 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000001869 81.0
HKD1_k127_7362795_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.152e-220 692.0
HKD1_k127_7362795_1 PFAM Rh family protein ammonium transporter K03320 - - 3.788e-198 634.0
HKD1_k127_7362795_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000218 78.0
HKD1_k127_7362795_2 ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 584.0
HKD1_k127_7362795_3 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 497.0
HKD1_k127_7362795_4 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 367.0
HKD1_k127_7362795_5 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001138 270.0
HKD1_k127_7362795_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007274 261.0
HKD1_k127_7362795_7 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 264.0
HKD1_k127_7362795_8 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000003797 189.0
HKD1_k127_7362795_9 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000005796 190.0
HKD1_k127_7371258_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1236.0
HKD1_k127_7371258_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 8.775e-196 617.0
HKD1_k127_7371258_10 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0001663 49.0
HKD1_k127_7371258_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 298.0
HKD1_k127_7371258_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 302.0
HKD1_k127_7371258_4 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000002169 248.0
HKD1_k127_7371258_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000003954 222.0
HKD1_k127_7371258_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000004873 222.0
HKD1_k127_7371258_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000007977 176.0
HKD1_k127_7371258_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000005479 132.0
HKD1_k127_7371258_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000006703 112.0
HKD1_k127_7381301_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 524.0
HKD1_k127_7381301_1 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
HKD1_k127_7381301_10 Yqey-like protein K09117 - - 0.0000000000000000000000000000008555 126.0
HKD1_k127_7381301_11 SCO1/SenC K07152 - - 0.0000000000000000000000000000008822 130.0
HKD1_k127_7381301_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000115 112.0
HKD1_k127_7381301_13 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000001217 57.0
HKD1_k127_7381301_2 GTP cyclohydrolase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 317.0
HKD1_k127_7381301_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 308.0
HKD1_k127_7381301_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002009 275.0
HKD1_k127_7381301_5 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
HKD1_k127_7381301_6 PFAM UvrB UvrC protein K08999 - - 0.000000000000000000000000000000000000000000000000000000000001231 219.0
HKD1_k127_7381301_7 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000001208 208.0
HKD1_k127_7381301_8 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000001535 154.0
HKD1_k127_7381301_9 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000003195 144.0
HKD1_k127_7427861_0 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 605.0
HKD1_k127_7427861_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 480.0
HKD1_k127_7427861_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 436.0
HKD1_k127_7427861_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 286.0
HKD1_k127_7427861_4 Outer membrane lipoprotein carrier protein LolA - - - 0.00000000000000000000000000000000005252 142.0
HKD1_k127_7427861_5 - - - - 0.000000000000000000000009013 108.0
HKD1_k127_7427861_6 Cytochrome c K00406,K08906 - - 0.0000000000000000401 86.0
HKD1_k127_7427861_7 Cytochrome c K00406,K08906 - - 0.000000000002213 79.0
HKD1_k127_7427861_8 - - - - 0.00000000000271 74.0
HKD1_k127_7439173_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1020.0
HKD1_k127_7439173_1 Protein-arginine kinase K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 448.0
HKD1_k127_7439173_10 Methylamine utilisation protein MauE - - - 0.00000001973 62.0
HKD1_k127_7439173_11 Rhodanese Homology Domain - - - 0.00000003348 63.0
HKD1_k127_7439173_12 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000001592 61.0
HKD1_k127_7439173_13 Parallel beta-helix repeats - - - 0.0001699 51.0
HKD1_k127_7439173_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 394.0
HKD1_k127_7439173_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
HKD1_k127_7439173_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 294.0
HKD1_k127_7439173_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004677 258.0
HKD1_k127_7439173_6 PFAM UvrB UvrC protein K19411 - - 0.0000000000000000000000000000000000000000000000000000001618 199.0
HKD1_k127_7439173_7 Histidine kinase K01768,K02482,K03406,K07647,K07653,K08475,K10125 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000005839 203.0
HKD1_k127_7439173_9 Protein of unknown function (DUF1573) - - - 0.00000000000000006872 93.0
HKD1_k127_7445193_0 exo-alpha-(2->6)-sialidase activity - - - 1.977e-219 751.0
HKD1_k127_7445193_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 605.0
HKD1_k127_7445193_10 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000002583 229.0
HKD1_k127_7445193_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.00000000000000000000000000000000000000000000001756 199.0
HKD1_k127_7445193_12 - - - - 0.00000000000000000000000005606 109.0
HKD1_k127_7445193_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000008184 124.0
HKD1_k127_7445193_14 DNA-sulfur modification-associated - - - 0.0000009495 61.0
HKD1_k127_7445193_15 - - - - 0.000009761 61.0
HKD1_k127_7445193_16 carboxylic ester hydrolase activity - - - 0.00008181 53.0
HKD1_k127_7445193_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
HKD1_k127_7445193_3 hydrolase activity, acting on ester bonds K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 463.0
HKD1_k127_7445193_4 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 449.0
HKD1_k127_7445193_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 412.0
HKD1_k127_7445193_6 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 372.0
HKD1_k127_7445193_7 WYL domain K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001318 269.0
HKD1_k127_7445193_8 FKBP-type peptidyl-prolyl cis-trans K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003583 238.0
HKD1_k127_7445193_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001516 237.0
HKD1_k127_7457718_0 Dipeptidyl peptidase IV (DPP IV) - - - 3.263e-248 791.0
HKD1_k127_7457718_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 467.0
HKD1_k127_7457718_2 DNA topoisomerase K02622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 443.0
HKD1_k127_7461800_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 367.0
HKD1_k127_7461800_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000584 267.0
HKD1_k127_7461800_2 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000001908 237.0
HKD1_k127_7461800_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000001283 226.0
HKD1_k127_7461800_4 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000008231 221.0
HKD1_k127_7461800_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000000001783 199.0
HKD1_k127_7461800_6 Domain of unknown function (DUF4272) - - - 0.000000000000000000000000000000000000000009853 161.0
HKD1_k127_7461800_7 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.000000000000000000000000000000001738 130.0
HKD1_k127_7514559_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 561.0
HKD1_k127_7514559_1 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K04496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 388.0
HKD1_k127_7514559_10 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000001222 144.0
HKD1_k127_7514559_11 Transcriptional regulator - - - 0.0000000000000000000000000001096 128.0
HKD1_k127_7514559_12 Transglutaminase-like - - - 0.0000000001715 69.0
HKD1_k127_7514559_2 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 380.0
HKD1_k127_7514559_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 381.0
HKD1_k127_7514559_4 Sigma-70 region 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 307.0
HKD1_k127_7514559_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 297.0
HKD1_k127_7514559_6 filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000301 273.0
HKD1_k127_7514559_7 filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
HKD1_k127_7514559_8 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
HKD1_k127_7514559_9 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000006255 206.0
HKD1_k127_7554151_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 514.0
HKD1_k127_7554151_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 377.0
HKD1_k127_7554151_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000009389 208.0
HKD1_k127_7554151_3 pathogenesis K00001,K00043,K01119,K01183,K03933,K08325,K13381,K13954,K19954 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 1.1.1.1,1.1.1.61,3.1.3.6,3.1.4.16,3.2.1.14,3.2.1.17 0.0000000000000001375 95.0
HKD1_k127_7571574_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1218.0
HKD1_k127_7571574_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.00000000000000000000000000000000000000000000000000002684 192.0
HKD1_k127_7571574_2 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000002366 114.0
HKD1_k127_7571574_3 Tetratricopeptide repeat - - - 0.00000000001565 78.0
HKD1_k127_7576095_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.963e-307 979.0
HKD1_k127_7576095_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000001383 231.0
HKD1_k127_7576095_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000003889 118.0
HKD1_k127_7576095_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000008645 104.0
HKD1_k127_758197_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 608.0
HKD1_k127_758197_1 SMART Immunoglobulin C2 type - - - 0.00000000000006181 83.0
HKD1_k127_7592577_0 alpha amylase, catalytic region - - - 3.833e-225 708.0
HKD1_k127_7592577_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 520.0
HKD1_k127_7592577_2 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
HKD1_k127_7592577_3 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000009242 143.0
HKD1_k127_7613366_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001291 295.0
HKD1_k127_7613366_1 2 iron, 2 sulfur cluster binding K07302 - 1.3.99.16 0.000000000000000000000000000001984 121.0
HKD1_k127_7613366_2 R3H domain - - - 0.0000000000000000000002018 102.0
HKD1_k127_7613366_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001409 98.0
HKD1_k127_7613366_4 Periplasmic or secreted lipoprotein K04065 - - 0.0000000000005001 74.0
HKD1_k127_7613366_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000007837 72.0
HKD1_k127_7613366_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000003412 61.0
HKD1_k127_7615352_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 8.774e-220 688.0
HKD1_k127_7615352_1 exo-alpha-(2->6)-sialidase activity - - - 1.508e-204 649.0
HKD1_k127_7615352_10 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000008605 163.0
HKD1_k127_7615352_11 - - - - 0.00000000000000000000000000000000000005945 152.0
HKD1_k127_7615352_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000174 86.0
HKD1_k127_7615352_13 Tetratricopeptide repeat - - - 0.000000000005822 76.0
HKD1_k127_7615352_14 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000004152 66.0
HKD1_k127_7615352_15 helix_turn_helix, Lux Regulon - - - 0.0000006466 52.0
HKD1_k127_7615352_2 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
HKD1_k127_7615352_3 Platelet-activating factor acetylhydrolase, plasma intracellular isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 308.0
HKD1_k127_7615352_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 296.0
HKD1_k127_7615352_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005036 279.0
HKD1_k127_7615352_6 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001497 247.0
HKD1_k127_7615352_7 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000001783 186.0
HKD1_k127_7615352_8 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000000005618 180.0
HKD1_k127_7615352_9 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000571 182.0
HKD1_k127_7639025_0 Belongs to the purine-cytosine permease (2.A.39) family - - - 2.879e-198 629.0
HKD1_k127_7639025_1 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 606.0
HKD1_k127_7639025_11 rhamnose metabolic process K03534 - 5.1.3.32 0.0000000000000000000000000000000000000006862 150.0
HKD1_k127_7639025_12 arginine decarboxylase K01585 - 4.1.1.19 0.000000000000000000000002618 103.0
HKD1_k127_7639025_13 YbbR-like protein - - - 0.0000002642 58.0
HKD1_k127_7639025_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 601.0
HKD1_k127_7639025_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 529.0
HKD1_k127_7639025_4 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 398.0
HKD1_k127_7639025_5 Glycosyl transferase family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000004595 262.0
HKD1_k127_7639025_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HKD1_k127_7639025_7 DisA bacterial checkpoint controller nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
HKD1_k127_7639025_8 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000003093 209.0
HKD1_k127_7639025_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000005676 176.0
HKD1_k127_7652158_0 PFAM Uncharacterised BCR, COG1649 - - - 6.506e-218 688.0
HKD1_k127_7652158_1 regulation of methylation-dependent chromatin silencing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 304.0
HKD1_k127_7652158_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 251.0
HKD1_k127_7652158_3 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000008714 215.0
HKD1_k127_7652158_4 Cytosine-specific methyltransferase - - - 0.000001483 60.0
HKD1_k127_7652158_5 restriction endonuclease K01155 - 3.1.21.4 0.000007993 53.0
HKD1_k127_7652158_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.0003851 45.0
HKD1_k127_7666386_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.31e-219 689.0
HKD1_k127_7666386_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 437.0
HKD1_k127_7666386_10 Putative prokaryotic signal transducing protein - - - 0.00009159 48.0
HKD1_k127_7666386_2 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 287.0
HKD1_k127_7666386_3 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
HKD1_k127_7666386_4 Permease MlaE - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
HKD1_k127_7666386_5 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000002405 214.0
HKD1_k127_7666386_6 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000001462 125.0
HKD1_k127_7666386_7 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000003866 87.0
HKD1_k127_7666386_8 MlaD protein K02067 - - 0.0000000000000002124 91.0
HKD1_k127_7666386_9 Aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000004059 63.0
HKD1_k127_7674054_0 alpha-L-rhamnosidase - - - 1.426e-196 632.0
HKD1_k127_7674054_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 382.0
HKD1_k127_7674054_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 286.0
HKD1_k127_7692404_0 Carboxylesterase family K03929 - - 1.035e-256 799.0
HKD1_k127_7692404_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 531.0
HKD1_k127_7692404_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
HKD1_k127_7692404_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000001804 198.0
HKD1_k127_7692404_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000001219 188.0
HKD1_k127_7692404_5 - - - - 0.00026 51.0
HKD1_k127_771553_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 2580.0
HKD1_k127_771553_1 ABC transporter transmembrane region K06160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 531.0
HKD1_k127_771553_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 346.0
HKD1_k127_771553_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003082 262.0
HKD1_k127_771553_4 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006712 254.0
HKD1_k127_7715776_0 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 511.0
HKD1_k127_7715776_1 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 254.0
HKD1_k127_7715776_2 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000000000000008993 180.0
HKD1_k127_7715776_3 Belongs to the UPF0312 family - - - 0.00000000001673 73.0
HKD1_k127_7715776_4 inositol 2-dehydrogenase activity - - - 0.000004329 51.0
HKD1_k127_773047_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0 1072.0
HKD1_k127_773047_1 mercury ion transmembrane transporter activity K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 5.649e-218 704.0
HKD1_k127_773047_10 FixH K09926 - - 0.00000000000000000000000002484 114.0
HKD1_k127_773047_11 Bacterial DNA polymerase III alpha subunit - - - 0.00000000008981 63.0
HKD1_k127_773047_12 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000003246 62.0
HKD1_k127_773047_2 cytochrome c oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 522.0
HKD1_k127_773047_3 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 365.0
HKD1_k127_773047_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 292.0
HKD1_k127_773047_5 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006919 274.0
HKD1_k127_773047_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000003725 202.0
HKD1_k127_773047_7 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000004069 196.0
HKD1_k127_773047_8 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000007978 176.0
HKD1_k127_773047_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008556 146.0
HKD1_k127_7747607_0 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 5.91e-209 663.0
HKD1_k127_7747607_1 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 435.0
HKD1_k127_7747607_10 Receptor family ligand binding region - - - 0.0000000000000709 83.0
HKD1_k127_7747607_11 - - - - 0.000004201 57.0
HKD1_k127_7747607_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004763 280.0
HKD1_k127_7747607_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003172 281.0
HKD1_k127_7747607_4 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000004455 185.0
HKD1_k127_7747607_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000006257 153.0
HKD1_k127_7747607_6 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000007577 145.0
HKD1_k127_7747607_7 cellulose binding - - - 0.00000000000000000000000000002088 132.0
HKD1_k127_7747607_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000003215 118.0
HKD1_k127_7747607_9 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000004143 85.0
HKD1_k127_7781990_0 AcrB/AcrD/AcrF family - - - 0.0 1026.0
HKD1_k127_7781990_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.224e-282 893.0
HKD1_k127_7781990_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 295.0
HKD1_k127_7781990_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000007609 63.0
HKD1_k127_7830123_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 387.0
HKD1_k127_7830123_1 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000005642 169.0
HKD1_k127_7830123_2 phosphoribosylamine-glycine ligase activity K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.00000000000000000000000000000000002338 137.0
HKD1_k127_7830123_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.00000000000000001431 85.0
HKD1_k127_7830123_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000001651 81.0
HKD1_k127_7831527_0 GlcNAc-PI de-N-acetylase - - - 1.225e-245 786.0
HKD1_k127_7831527_1 Lysine-2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 537.0
HKD1_k127_7831527_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 411.0
HKD1_k127_7831527_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 310.0
HKD1_k127_7831527_4 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 290.0
HKD1_k127_7831527_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000004204 189.0
HKD1_k127_7831527_6 Putative regulatory protein - - - 0.000000000000000000000000000007146 123.0
HKD1_k127_7831527_7 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000001026 120.0
HKD1_k127_7831527_8 - - - - 0.00000000000000000000009594 99.0
HKD1_k127_7831527_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000001115 100.0
HKD1_k127_7881598_0 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 492.0
HKD1_k127_7881598_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000001963 198.0
HKD1_k127_7881598_2 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000000000000127 156.0
HKD1_k127_7881598_3 - - - - 0.00000000000000000000000003857 111.0
HKD1_k127_7881598_4 Lipid A Biosynthesis N-terminal domain - - - 0.00000001377 63.0
HKD1_k127_7881598_5 thiamine diphosphate biosynthetic process K03154 - - 0.000006251 51.0
HKD1_k127_7881598_6 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000007813 55.0
HKD1_k127_7920068_0 PFAM CBS domain containing protein K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 374.0
HKD1_k127_7920068_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 357.0
HKD1_k127_7920068_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
HKD1_k127_7920068_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000277 189.0
HKD1_k127_7920068_4 PFAM Tetratricopeptide repeat - - - 0.000002991 58.0
HKD1_k127_7988621_0 extracellular matrix structural constituent - - - 0.0 1283.0
HKD1_k127_7988621_1 Highly conserved protein containing a thioredoxin domain - - - 0.0 1056.0
HKD1_k127_7988621_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 371.0
HKD1_k127_7988621_11 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000005588 258.0
HKD1_k127_7988621_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000003746 150.0
HKD1_k127_7988621_13 - - - - 0.0000000000000000000000000000000005569 134.0
HKD1_k127_7988621_14 Prokaryotic N-terminal methylation motif - - - 0.00000000000004104 83.0
HKD1_k127_7988621_15 SnoaL-like domain - - - 0.000000000003095 73.0
HKD1_k127_7988621_16 cellulose binding K13735 - - 0.0000000003727 74.0
HKD1_k127_7988621_17 O-methyltransferase - - - 0.00009347 49.0
HKD1_k127_7988621_18 - - - - 0.0007599 52.0
HKD1_k127_7988621_19 Fibronectin type 3 domain - - - 0.0008013 53.0
HKD1_k127_7988621_2 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 3.729e-296 930.0
HKD1_k127_7988621_3 extracellular matrix structural constituent - - - 2.587e-243 781.0
HKD1_k127_7988621_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.032e-205 653.0
HKD1_k127_7988621_5 rRNA (guanine-N2-)-methyltransferase activity K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 570.0
HKD1_k127_7988621_6 quinone binding K01829,K03673,K03805,K03981,K12228 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 485.0
HKD1_k127_7988621_7 methyltransferase K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 511.0
HKD1_k127_7988621_8 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 394.0
HKD1_k127_7988621_9 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 414.0
HKD1_k127_8013262_0 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 441.0
HKD1_k127_8013262_1 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 371.0
HKD1_k127_812388_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 460.0
HKD1_k127_812388_1 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000001397 233.0
HKD1_k127_812388_2 glycosyl transferase family 39 K00721 - 2.4.1.83 0.000000000215 73.0
HKD1_k127_812388_3 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000001622 61.0
HKD1_k127_839957_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 516.0
HKD1_k127_839957_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 512.0
HKD1_k127_839957_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 474.0
HKD1_k127_839957_3 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 456.0
HKD1_k127_839957_4 Dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 337.0
HKD1_k127_839957_5 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000000000000000000000001963 179.0
HKD1_k127_839957_6 - - - - 0.000000000000000593 91.0
HKD1_k127_839957_7 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.000000000001301 76.0
HKD1_k127_839957_8 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08304 GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000003811 61.0
HKD1_k127_876312_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1228.0
HKD1_k127_876312_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 336.0
HKD1_k127_876312_2 Bacterial regulatory proteins, tetR family - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000003604 128.0
HKD1_k127_936465_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.062e-282 886.0
HKD1_k127_936465_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 579.0
HKD1_k127_936465_10 Membrane bound O-acyl transferase family - - - 0.000000000000000000000000000000000000000000000000000000004052 215.0
HKD1_k127_936465_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000002967 177.0
HKD1_k127_936465_12 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000008364 150.0
HKD1_k127_936465_13 NUDIX domain K03574,K03575 - 3.6.1.55 0.000000000000000000000000000000000472 135.0
HKD1_k127_936465_14 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000000000000053 124.0
HKD1_k127_936465_15 NIL domain - - - 0.000000000000000000000000000009562 121.0
HKD1_k127_936465_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000002545 112.0
HKD1_k127_936465_18 PFAM regulatory protein LuxR - - - 0.000000000000000000000002314 104.0
HKD1_k127_936465_19 - - - - 0.00000000000000000000009564 102.0
HKD1_k127_936465_2 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 567.0
HKD1_k127_936465_21 protein trimerization - - - 0.0000001446 62.0
HKD1_k127_936465_22 Protein of unknown function, DUF393 - - - 0.0009817 51.0
HKD1_k127_936465_3 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 508.0
HKD1_k127_936465_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 333.0
HKD1_k127_936465_5 coenzyme binding K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 325.0
HKD1_k127_936465_6 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006379 269.0
HKD1_k127_936465_7 conserved protein (COG2071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006891 256.0
HKD1_k127_936465_8 Uncharacterized conserved protein (COG2071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 254.0
HKD1_k127_936465_9 MarR family - - - 0.00000000000000000000000000000000000000000000000000000000000004346 220.0