Overview

ID MAG01745
Name HKD1_bin.63
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfuromonadia
Order Geobacterales
Family Geobacteraceae
Genus Geomonas
Species
Assembly information
Completeness (%) 99.99
Contamination (%) 3.42
GC content (%) 60.0
N50 (bp) 60,113
Genome size (bp) 4,797,112

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3823

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1009621_0 AcrB/AcrD/AcrF family - - - 0.0 2304.0
HKD1_k127_1009621_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1313.0
HKD1_k127_1009621_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 464.0
HKD1_k127_1009621_11 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 419.0
HKD1_k127_1009621_12 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 389.0
HKD1_k127_1009621_13 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 397.0
HKD1_k127_1009621_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 372.0
HKD1_k127_1009621_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 323.0
HKD1_k127_1009621_16 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 299.0
HKD1_k127_1009621_17 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005506 262.0
HKD1_k127_1009621_18 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004937 274.0
HKD1_k127_1009621_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1155.0
HKD1_k127_1009621_21 Sulfate ABC transporter substrate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000009687 205.0
HKD1_k127_1009621_22 sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000001095 187.0
HKD1_k127_1009621_23 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000001584 179.0
HKD1_k127_1009621_25 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000475 105.0
HKD1_k127_1009621_26 ACT domain K03567 - - 0.0000000000000000000001228 104.0
HKD1_k127_1009621_27 antisigma factor binding K04749,K06378 - - 0.00000000000000000001154 95.0
HKD1_k127_1009621_28 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000001032 89.0
HKD1_k127_1009621_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 997.0
HKD1_k127_1009621_30 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000002158 87.0
HKD1_k127_1009621_32 Integrase core domain K07497 - - 0.000003752 49.0
HKD1_k127_1009621_4 Cytochrome c554 and c-prime - - - 3.019e-241 753.0
HKD1_k127_1009621_5 Bacterial periplasmic substrate-binding proteins K02030 - - 4.559e-207 660.0
HKD1_k127_1009621_6 Bacterial regulatory protein, Fis family - - - 2.851e-198 638.0
HKD1_k127_1009621_7 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 558.0
HKD1_k127_1009621_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 552.0
HKD1_k127_1009621_9 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 500.0
HKD1_k127_1037103_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2507.0
HKD1_k127_1037103_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2321.0
HKD1_k127_1037103_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 574.0
HKD1_k127_1037103_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 522.0
HKD1_k127_1037103_12 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 426.0
HKD1_k127_1037103_13 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 419.0
HKD1_k127_1037103_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 402.0
HKD1_k127_1037103_15 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 396.0
HKD1_k127_1037103_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 392.0
HKD1_k127_1037103_17 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 379.0
HKD1_k127_1037103_18 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 358.0
HKD1_k127_1037103_19 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 359.0
HKD1_k127_1037103_2 Required for chromosome condensation and partitioning K03529 - - 0.0 1742.0
HKD1_k127_1037103_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 344.0
HKD1_k127_1037103_21 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 313.0
HKD1_k127_1037103_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 302.0
HKD1_k127_1037103_23 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
HKD1_k127_1037103_24 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 292.0
HKD1_k127_1037103_25 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 290.0
HKD1_k127_1037103_26 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000397 279.0
HKD1_k127_1037103_27 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 273.0
HKD1_k127_1037103_28 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
HKD1_k127_1037103_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004536 261.0
HKD1_k127_1037103_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1330.0
HKD1_k127_1037103_30 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
HKD1_k127_1037103_31 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001288 260.0
HKD1_k127_1037103_32 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 254.0
HKD1_k127_1037103_33 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001264 246.0
HKD1_k127_1037103_34 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000009546 240.0
HKD1_k127_1037103_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001544 230.0
HKD1_k127_1037103_36 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000000000003732 218.0
HKD1_k127_1037103_37 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002534 213.0
HKD1_k127_1037103_38 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003472 205.0
HKD1_k127_1037103_39 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004014 205.0
HKD1_k127_1037103_4 Endoribonuclease that initiates mRNA decay K18682 - - 1.839e-302 932.0
HKD1_k127_1037103_40 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002317 196.0
HKD1_k127_1037103_41 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000002599 192.0
HKD1_k127_1037103_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000006837 178.0
HKD1_k127_1037103_43 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000005026 175.0
HKD1_k127_1037103_44 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000004875 160.0
HKD1_k127_1037103_45 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000001616 128.0
HKD1_k127_1037103_46 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000006709 125.0
HKD1_k127_1037103_47 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000006812 107.0
HKD1_k127_1037103_48 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000208 105.0
HKD1_k127_1037103_49 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000005722 104.0
HKD1_k127_1037103_5 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.017e-263 815.0
HKD1_k127_1037103_51 - - - - 0.0000000000000001658 79.0
HKD1_k127_1037103_52 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002608 76.0
HKD1_k127_1037103_53 - - - - 0.000000000000008306 76.0
HKD1_k127_1037103_54 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000008137 60.0
HKD1_k127_1037103_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.174e-253 783.0
HKD1_k127_1037103_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.688e-233 724.0
HKD1_k127_1037103_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 2.253e-225 702.0
HKD1_k127_1037103_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.403e-215 669.0
HKD1_k127_1067411_0 DEAD DEAH box K03724 - - 0.0 2167.0
HKD1_k127_1067411_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0 1686.0
HKD1_k127_1067411_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 9.571e-271 835.0
HKD1_k127_1067411_11 Tetratricopeptide TPR_2 repeat protein - - - 1.798e-266 831.0
HKD1_k127_1067411_12 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.679e-260 807.0
HKD1_k127_1067411_13 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 3.151e-236 735.0
HKD1_k127_1067411_14 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 7.788e-212 663.0
HKD1_k127_1067411_15 AAA domain K07028 - - 2.977e-210 664.0
HKD1_k127_1067411_16 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 610.0
HKD1_k127_1067411_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 600.0
HKD1_k127_1067411_18 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 557.0
HKD1_k127_1067411_19 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 563.0
HKD1_k127_1067411_2 outer membrane autotransporter barrel domain - - - 0.0 1461.0
HKD1_k127_1067411_20 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 544.0
HKD1_k127_1067411_21 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
HKD1_k127_1067411_22 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 542.0
HKD1_k127_1067411_23 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 557.0
HKD1_k127_1067411_24 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 537.0
HKD1_k127_1067411_25 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 497.0
HKD1_k127_1067411_26 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 491.0
HKD1_k127_1067411_27 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
HKD1_k127_1067411_28 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 447.0
HKD1_k127_1067411_29 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 439.0
HKD1_k127_1067411_3 histidine kinase HAMP region domain protein - - - 0.0 1276.0
HKD1_k127_1067411_30 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 443.0
HKD1_k127_1067411_31 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 440.0
HKD1_k127_1067411_32 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 418.0
HKD1_k127_1067411_33 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 411.0
HKD1_k127_1067411_34 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 401.0
HKD1_k127_1067411_35 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 392.0
HKD1_k127_1067411_36 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 366.0
HKD1_k127_1067411_37 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 312.0
HKD1_k127_1067411_38 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 306.0
HKD1_k127_1067411_39 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
HKD1_k127_1067411_4 PFAM type II and III secretion system protein K02666 - - 0.0 1206.0
HKD1_k127_1067411_40 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 297.0
HKD1_k127_1067411_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
HKD1_k127_1067411_42 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
HKD1_k127_1067411_43 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005649 276.0
HKD1_k127_1067411_44 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 252.0
HKD1_k127_1067411_45 PFAM ATP-binding region, ATPase domain protein K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009168 254.0
HKD1_k127_1067411_46 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000222 242.0
HKD1_k127_1067411_47 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001656 238.0
HKD1_k127_1067411_48 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
HKD1_k127_1067411_49 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000008843 233.0
HKD1_k127_1067411_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1135.0
HKD1_k127_1067411_50 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000000000000000000000000000000000000000000002312 210.0
HKD1_k127_1067411_51 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000000000000002251 203.0
HKD1_k127_1067411_52 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000006752 209.0
HKD1_k127_1067411_53 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
HKD1_k127_1067411_54 - - - - 0.00000000000000000000000000000000000000000000000000008012 188.0
HKD1_k127_1067411_55 - - - - 0.00000000000000000000000000000000000000000000000006179 180.0
HKD1_k127_1067411_56 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000003289 179.0
HKD1_k127_1067411_57 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K01802,K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000001236 164.0
HKD1_k127_1067411_58 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000007422 164.0
HKD1_k127_1067411_59 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000005728 132.0
HKD1_k127_1067411_6 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0 1118.0
HKD1_k127_1067411_61 Diguanylate cyclase - - - 0.000000000000000000000000017 128.0
HKD1_k127_1067411_62 Roadblock/LC7 domain - - - 0.00000000000000000000000002812 111.0
HKD1_k127_1067411_68 Periplasmic or secreted lipoprotein - - - 0.00001153 49.0
HKD1_k127_1067411_69 - - - - 0.00003094 54.0
HKD1_k127_1067411_7 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 2.117e-284 882.0
HKD1_k127_1067411_70 PFAM helix-turn-helix domain protein - - - 0.0002677 44.0
HKD1_k127_1067411_8 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.937e-279 861.0
HKD1_k127_1067411_9 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 3.068e-275 852.0
HKD1_k127_1100970_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1485.0
HKD1_k127_1100970_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1363.0
HKD1_k127_1100970_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.249e-211 660.0
HKD1_k127_1100970_11 deoxyhypusine monooxygenase activity - - - 5.761e-207 654.0
HKD1_k127_1100970_12 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.731e-205 649.0
HKD1_k127_1100970_13 Voltage gated chloride channel - - - 1.594e-198 636.0
HKD1_k127_1100970_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 607.0
HKD1_k127_1100970_15 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 616.0
HKD1_k127_1100970_16 GGGtGRT protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 567.0
HKD1_k127_1100970_17 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 559.0
HKD1_k127_1100970_18 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 563.0
HKD1_k127_1100970_19 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 533.0
HKD1_k127_1100970_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1124.0
HKD1_k127_1100970_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 532.0
HKD1_k127_1100970_21 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 511.0
HKD1_k127_1100970_22 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 482.0
HKD1_k127_1100970_23 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
HKD1_k127_1100970_24 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 424.0
HKD1_k127_1100970_25 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 432.0
HKD1_k127_1100970_26 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 391.0
HKD1_k127_1100970_27 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 318.0
HKD1_k127_1100970_28 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 314.0
HKD1_k127_1100970_29 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000661 299.0
HKD1_k127_1100970_3 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.0 1079.0
HKD1_k127_1100970_30 abc transporter atp-binding protein K02065,K02068,K02071,K05773,K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
HKD1_k127_1100970_31 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
HKD1_k127_1100970_32 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000000000000000000005522 206.0
HKD1_k127_1100970_33 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000001261 212.0
HKD1_k127_1100970_34 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000005267 177.0
HKD1_k127_1100970_35 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000001157 172.0
HKD1_k127_1100970_36 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001837 154.0
HKD1_k127_1100970_37 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000004411 118.0
HKD1_k127_1100970_38 glutathione-regulated potassium exporter activity - - - 0.000000000000000000009818 94.0
HKD1_k127_1100970_39 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001294 88.0
HKD1_k127_1100970_4 Histidine kinase K07711 - 2.7.13.3 0.0 1073.0
HKD1_k127_1100970_40 - - - - 0.0000009344 50.0
HKD1_k127_1100970_41 PFAM Sodium hydrogen exchanger family K03455 - - 0.0001847 45.0
HKD1_k127_1100970_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.564e-251 778.0
HKD1_k127_1100970_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 7.855e-247 767.0
HKD1_k127_1100970_7 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 2.436e-244 758.0
HKD1_k127_1100970_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.228e-237 745.0
HKD1_k127_1100970_9 SMART Elongator protein 3 MiaB NifB K22227 - - 3.056e-234 728.0
HKD1_k127_1116170_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1172.0
HKD1_k127_1116170_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.86e-293 902.0
HKD1_k127_1116170_10 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001699 255.0
HKD1_k127_1116170_11 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000002281 195.0
HKD1_k127_1116170_12 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000003637 134.0
HKD1_k127_1116170_2 Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 1.704e-219 685.0
HKD1_k127_1116170_3 Cys Met metabolism K01760 - 4.4.1.8 1.079e-209 655.0
HKD1_k127_1116170_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 528.0
HKD1_k127_1116170_5 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 393.0
HKD1_k127_1116170_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 351.0
HKD1_k127_1116170_7 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 351.0
HKD1_k127_1116170_8 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 333.0
HKD1_k127_1116170_9 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 282.0
HKD1_k127_1120213_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2166.0
HKD1_k127_1120213_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1442.0
HKD1_k127_1120213_10 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 9.957e-234 730.0
HKD1_k127_1120213_11 Histidine kinase K13040 - 2.7.13.3 9.675e-228 721.0
HKD1_k127_1120213_12 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.123e-211 661.0
HKD1_k127_1120213_13 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.366e-208 650.0
HKD1_k127_1120213_14 FIST N domain - - - 2.306e-207 649.0
HKD1_k127_1120213_15 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.026e-203 651.0
HKD1_k127_1120213_16 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 616.0
HKD1_k127_1120213_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 593.0
HKD1_k127_1120213_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 569.0
HKD1_k127_1120213_19 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 445.0
HKD1_k127_1120213_2 SMART Elongator protein 3 MiaB NifB - - - 0.0 1382.0
HKD1_k127_1120213_20 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 434.0
HKD1_k127_1120213_21 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 407.0
HKD1_k127_1120213_22 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 404.0
HKD1_k127_1120213_23 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 387.0
HKD1_k127_1120213_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386,K20011 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 375.0
HKD1_k127_1120213_25 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 380.0
HKD1_k127_1120213_26 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 353.0
HKD1_k127_1120213_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 323.0
HKD1_k127_1120213_28 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
HKD1_k127_1120213_29 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 290.0
HKD1_k127_1120213_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1175.0
HKD1_k127_1120213_30 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
HKD1_k127_1120213_31 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006197 248.0
HKD1_k127_1120213_32 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000005679 245.0
HKD1_k127_1120213_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
HKD1_k127_1120213_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000006708 215.0
HKD1_k127_1120213_36 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000000000000000001374 189.0
HKD1_k127_1120213_37 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000005047 190.0
HKD1_k127_1120213_38 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000083 196.0
HKD1_k127_1120213_39 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000005494 178.0
HKD1_k127_1120213_4 DEAD_2 K10844 - 3.6.4.12 0.0 1174.0
HKD1_k127_1120213_40 ATP synthesis coupled electron transport K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000008561 177.0
HKD1_k127_1120213_41 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.000000000000000000000000000000000000000000000008848 172.0
HKD1_k127_1120213_42 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000001391 173.0
HKD1_k127_1120213_43 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000000000000000003856 171.0
HKD1_k127_1120213_44 - - - - 0.000000000000000000000000000000000000000000001992 168.0
HKD1_k127_1120213_45 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000002191 167.0
HKD1_k127_1120213_47 cytochrome - - - 0.0000000000000000000000000000000000000000002389 161.0
HKD1_k127_1120213_48 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000522 106.0
HKD1_k127_1120213_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.5e-322 996.0
HKD1_k127_1120213_6 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.032e-299 935.0
HKD1_k127_1120213_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 6.412e-252 780.0
HKD1_k127_1120213_8 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00334,K00335 - 1.6.5.3 4.583e-251 777.0
HKD1_k127_1120213_9 Proton-conducting membrane transporter K00342 - 1.6.5.3 4.199e-247 770.0
HKD1_k127_1151294_0 Belongs to the NifD NifK NifE NifN family K02587 - - 0.0 1677.0
HKD1_k127_1151294_1 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 359.0
HKD1_k127_1151294_2 Pfam Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000000000000000000000000000000000001398 239.0
HKD1_k127_1151294_3 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000004447 191.0
HKD1_k127_1151294_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000002706 179.0
HKD1_k127_1166684_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.631e-319 980.0
HKD1_k127_1166684_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.203e-268 828.0
HKD1_k127_1166684_10 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 504.0
HKD1_k127_1166684_11 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 506.0
HKD1_k127_1166684_12 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 499.0
HKD1_k127_1166684_13 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 467.0
HKD1_k127_1166684_14 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 451.0
HKD1_k127_1166684_15 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 442.0
HKD1_k127_1166684_16 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 399.0
HKD1_k127_1166684_17 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 327.0
HKD1_k127_1166684_18 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 323.0
HKD1_k127_1166684_19 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 310.0
HKD1_k127_1166684_2 PFAM ResB family protein K07399 - - 2.334e-252 783.0
HKD1_k127_1166684_20 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
HKD1_k127_1166684_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005337 255.0
HKD1_k127_1166684_22 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
HKD1_k127_1166684_23 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000004162 254.0
HKD1_k127_1166684_24 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009668 241.0
HKD1_k127_1166684_25 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HKD1_k127_1166684_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001064 236.0
HKD1_k127_1166684_27 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000005773 187.0
HKD1_k127_1166684_29 O-acyltransferase activity - - - 0.0000000000000000000000000000000007312 138.0
HKD1_k127_1166684_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 2.209e-246 768.0
HKD1_k127_1166684_30 - - - - 0.000000000000000000000000009582 111.0
HKD1_k127_1166684_32 - - - - 0.00007093 47.0
HKD1_k127_1166684_4 Belongs to the GARS family K01945 - 6.3.4.13 3.449e-245 763.0
HKD1_k127_1166684_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 1.353e-214 670.0
HKD1_k127_1166684_6 Polysaccharide biosynthesis protein K03328 - - 1.229e-205 651.0
HKD1_k127_1166684_7 PFAM Glycosyl transferase, group 1 - - - 8.956e-203 636.0
HKD1_k127_1166684_8 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 608.0
HKD1_k127_1166684_9 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 542.0
HKD1_k127_1173020_0 AAA domain K03546 - - 0.0 1174.0
HKD1_k127_1173020_1 Calcineurin-like phosphoesterase K03547 - - 1.173e-205 650.0
HKD1_k127_1173020_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 591.0
HKD1_k127_1173020_3 Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 426.0
HKD1_k127_1173020_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
HKD1_k127_1173020_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 376.0
HKD1_k127_1173020_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 320.0
HKD1_k127_1219587_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1588.0
HKD1_k127_1219587_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1260.0
HKD1_k127_1219587_10 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000002453 110.0
HKD1_k127_1219587_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.834e-229 711.0
HKD1_k127_1219587_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 611.0
HKD1_k127_1219587_4 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 482.0
HKD1_k127_1219587_5 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 441.0
HKD1_k127_1219587_6 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 355.0
HKD1_k127_1219587_7 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000001896 207.0
HKD1_k127_1219587_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000009382 163.0
HKD1_k127_1219587_9 PFAM cytochrome c class I - - - 0.00000000000000000000000000000000001256 138.0
HKD1_k127_1253814_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1577.0
HKD1_k127_1253814_1 Glycogen debranching enzyme - - - 0.0 1088.0
HKD1_k127_1253814_10 MoeA domain protein domain I and II K03750 - 2.10.1.1 4.219e-199 626.0
HKD1_k127_1253814_11 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 592.0
HKD1_k127_1253814_12 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 580.0
HKD1_k127_1253814_13 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 556.0
HKD1_k127_1253814_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 538.0
HKD1_k127_1253814_15 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 542.0
HKD1_k127_1253814_16 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 544.0
HKD1_k127_1253814_17 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 532.0
HKD1_k127_1253814_18 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
HKD1_k127_1253814_19 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 408.0
HKD1_k127_1253814_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0 1030.0
HKD1_k127_1253814_20 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 402.0
HKD1_k127_1253814_21 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 376.0
HKD1_k127_1253814_22 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 364.0
HKD1_k127_1253814_23 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
HKD1_k127_1253814_24 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 348.0
HKD1_k127_1253814_25 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
HKD1_k127_1253814_26 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
HKD1_k127_1253814_27 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001452 252.0
HKD1_k127_1253814_28 L,D-transpeptidase catalytic domain K19234,K19236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
HKD1_k127_1253814_29 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000005147 203.0
HKD1_k127_1253814_3 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 2.045e-304 943.0
HKD1_k127_1253814_30 translation initiation factor activity K07126,K08930 - - 0.000000000000000000000000000000000000000000000000000008501 208.0
HKD1_k127_1253814_31 filamentation induced by cAMP - - - 0.0000000000000000000000000000000000000000003582 161.0
HKD1_k127_1253814_32 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000000000000000000000000000001584 158.0
HKD1_k127_1253814_33 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000199 105.0
HKD1_k127_1253814_34 protein secretion K03116 - - 0.000000000000000000000002375 103.0
HKD1_k127_1253814_35 Protein of unknown function (DUF2795) - - - 0.00000000000000000000003144 102.0
HKD1_k127_1253814_36 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000000006061 100.0
HKD1_k127_1253814_37 - - - - 0.00000000000000000766 84.0
HKD1_k127_1253814_39 Post-segregation antitoxin CcdA K19164 - - 0.00006179 51.0
HKD1_k127_1253814_4 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 5.581e-300 932.0
HKD1_k127_1253814_40 - - - - 0.0001219 48.0
HKD1_k127_1253814_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.557e-266 829.0
HKD1_k127_1253814_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 6.787e-261 805.0
HKD1_k127_1253814_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 - 2.867e-235 734.0
HKD1_k127_1253814_8 PFAM Polysulphide reductase, NrfD - - - 8.82e-227 706.0
HKD1_k127_1253814_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.822e-211 661.0
HKD1_k127_1288984_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.781e-281 864.0
HKD1_k127_1288984_1 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 2.68e-253 795.0
HKD1_k127_1288984_13 Histidine kinase - - - 0.0003912 43.0
HKD1_k127_1288984_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.026e-242 757.0
HKD1_k127_1288984_3 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 6.799e-211 664.0
HKD1_k127_1288984_4 MFS/sugar transport protein - - - 1.726e-195 616.0
HKD1_k127_1288984_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 401.0
HKD1_k127_1288984_6 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 375.0
HKD1_k127_1288984_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K01829,K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000001431 196.0
HKD1_k127_1288984_9 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000000000006361 145.0
HKD1_k127_1288985_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1555.0
HKD1_k127_1288985_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1389.0
HKD1_k127_1288985_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 505.0
HKD1_k127_1288985_11 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 488.0
HKD1_k127_1288985_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
HKD1_k127_1288985_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 450.0
HKD1_k127_1288985_14 GGDEF domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 416.0
HKD1_k127_1288985_15 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 385.0
HKD1_k127_1288985_16 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 370.0
HKD1_k127_1288985_17 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000366 274.0
HKD1_k127_1288985_18 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
HKD1_k127_1288985_19 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000003153 230.0
HKD1_k127_1288985_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0 1036.0
HKD1_k127_1288985_20 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
HKD1_k127_1288985_21 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000000000000000006301 222.0
HKD1_k127_1288985_22 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HKD1_k127_1288985_24 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000001999 165.0
HKD1_k127_1288985_25 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000003584 163.0
HKD1_k127_1288985_26 TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 - - - 0.00000000000000000000000000000000006305 147.0
HKD1_k127_1288985_27 PFAM DSBA oxidoreductase - - - 0.000000000000007493 85.0
HKD1_k127_1288985_3 aminotransferase class I and II - - - 1.764e-255 793.0
HKD1_k127_1288985_4 regulator, PATAN and FRGAF domain-containing - - - 2.769e-255 802.0
HKD1_k127_1288985_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.506e-254 790.0
HKD1_k127_1288985_6 PFAM ABC transporter K05776 - - 7.727e-227 711.0
HKD1_k127_1288985_7 HEAT repeat - - - 6.857e-225 715.0
HKD1_k127_1288985_8 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 575.0
HKD1_k127_1288985_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 568.0
HKD1_k127_1309948_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 541.0
HKD1_k127_1309948_1 Heavy metal transcriptional response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 344.0
HKD1_k127_1309948_2 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 304.0
HKD1_k127_1309948_3 denitrification pathway - - - 0.00000001209 67.0
HKD1_k127_1309948_4 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000001379 59.0
HKD1_k127_1324102_0 MMPL family K07003 - - 0.0 1026.0
HKD1_k127_1324102_1 Aromatic amino acid lyase K01745 - 4.3.1.3 4.929e-302 930.0
HKD1_k127_1324102_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 322.0
HKD1_k127_1324102_11 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 282.0
HKD1_k127_1324102_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003295 273.0
HKD1_k127_1324102_13 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
HKD1_k127_1324102_14 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000006386 230.0
HKD1_k127_1324102_15 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000001171 214.0
HKD1_k127_1324102_16 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
HKD1_k127_1324102_17 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000123 177.0
HKD1_k127_1324102_18 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000003726 154.0
HKD1_k127_1324102_19 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000001024 153.0
HKD1_k127_1324102_2 B12 binding domain - - - 1.856e-228 711.0
HKD1_k127_1324102_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000006246 143.0
HKD1_k127_1324102_21 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000003149 112.0
HKD1_k127_1324102_22 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000005813 108.0
HKD1_k127_1324102_23 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ K02372 - 4.2.1.59 0.000000000009996 70.0
HKD1_k127_1324102_24 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000695 46.0
HKD1_k127_1324102_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 4.555e-218 681.0
HKD1_k127_1324102_4 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 615.0
HKD1_k127_1324102_5 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 597.0
HKD1_k127_1324102_6 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 512.0
HKD1_k127_1324102_7 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 416.0
HKD1_k127_1324102_8 PFAM FAD dependent oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 391.0
HKD1_k127_1324102_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 352.0
HKD1_k127_1332994_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1292.0
HKD1_k127_1332994_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.522e-316 968.0
HKD1_k127_1332994_10 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 326.0
HKD1_k127_1332994_11 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 338.0
HKD1_k127_1332994_12 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 295.0
HKD1_k127_1332994_13 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
HKD1_k127_1332994_14 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000000003446 218.0
HKD1_k127_1332994_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000001141 202.0
HKD1_k127_1332994_16 Helix-turn-helix domain of resolvase - - - 0.0000000000000000000000000000000000000000000000000001848 192.0
HKD1_k127_1332994_17 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000003312 184.0
HKD1_k127_1332994_18 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000007656 181.0
HKD1_k127_1332994_19 PFAM Polyketide cyclase dehydrase K03396 - 4.4.1.22 0.00000000000000000000000000000000000000000000000002742 183.0
HKD1_k127_1332994_2 PFAM Polysaccharide export protein - - - 1.922e-314 989.0
HKD1_k127_1332994_20 - - - - 0.000000000000000000000000000000000000006997 148.0
HKD1_k127_1332994_21 Thioesterase superfamily - - - 0.000000000000000000000000000000000504 136.0
HKD1_k127_1332994_22 Cyclase dehydrase - - - 0.00000000000000000000000000005272 121.0
HKD1_k127_1332994_23 Mycolic acid cyclopropane synthetase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000002204 111.0
HKD1_k127_1332994_26 Opacity family porin protein - - - 0.000000000000002454 83.0
HKD1_k127_1332994_3 Domain of unknown function (DUF4070) - - - 2.414e-246 768.0
HKD1_k127_1332994_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 6.525e-222 694.0
HKD1_k127_1332994_5 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 517.0
HKD1_k127_1332994_6 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 511.0
HKD1_k127_1332994_7 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 377.0
HKD1_k127_1332994_8 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 355.0
HKD1_k127_1332994_9 hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 355.0
HKD1_k127_1451855_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1735.0
HKD1_k127_1451855_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1637.0
HKD1_k127_1451855_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.948e-260 805.0
HKD1_k127_1451855_11 Domain of unknown function (DUF3488) - - - 2.022e-237 749.0
HKD1_k127_1451855_12 PFAM peptidase M16 domain protein - - - 2.642e-227 708.0
HKD1_k127_1451855_13 PFAM peptidase M29, aminopeptidase II K19689 - - 3.23e-224 696.0
HKD1_k127_1451855_14 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.548e-222 696.0
HKD1_k127_1451855_15 response regulator K02481 - - 3.94e-221 691.0
HKD1_k127_1451855_16 Participates in both transcription termination and antitermination K02600 - - 8.516e-218 679.0
HKD1_k127_1451855_17 - - - - 1.141e-209 659.0
HKD1_k127_1451855_18 Iron-containing alcohol dehydrogenase K00086 - 1.1.1.202 2.75e-207 649.0
HKD1_k127_1451855_19 acyl-coa dehydrogenase K00248 - 1.3.8.1 5.831e-200 629.0
HKD1_k127_1451855_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1417.0
HKD1_k127_1451855_20 PFAM natural resistance-associated macrophage protein - - - 6.622e-200 630.0
HKD1_k127_1451855_21 Biotin-lipoyl like K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 605.0
HKD1_k127_1451855_22 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 580.0
HKD1_k127_1451855_23 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 578.0
HKD1_k127_1451855_24 TOBE domain K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 578.0
HKD1_k127_1451855_25 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 576.0
HKD1_k127_1451855_26 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 577.0
HKD1_k127_1451855_27 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 574.0
HKD1_k127_1451855_28 PFAM Peptidase M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 569.0
HKD1_k127_1451855_29 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 561.0
HKD1_k127_1451855_3 malic protein domain protein K00029 - 1.1.1.40 0.0 1313.0
HKD1_k127_1451855_30 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 560.0
HKD1_k127_1451855_31 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 544.0
HKD1_k127_1451855_32 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 551.0
HKD1_k127_1451855_33 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 536.0
HKD1_k127_1451855_34 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 522.0
HKD1_k127_1451855_35 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 518.0
HKD1_k127_1451855_36 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 529.0
HKD1_k127_1451855_37 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 490.0
HKD1_k127_1451855_38 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 496.0
HKD1_k127_1451855_39 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 479.0
HKD1_k127_1451855_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1238.0
HKD1_k127_1451855_40 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 471.0
HKD1_k127_1451855_41 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 461.0
HKD1_k127_1451855_42 PFAM outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 468.0
HKD1_k127_1451855_43 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 447.0
HKD1_k127_1451855_44 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 462.0
HKD1_k127_1451855_45 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 433.0
HKD1_k127_1451855_46 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 430.0
HKD1_k127_1451855_47 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 397.0
HKD1_k127_1451855_48 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 398.0
HKD1_k127_1451855_49 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 396.0
HKD1_k127_1451855_5 type II and III secretion system protein K02453 - - 0.0 1050.0
HKD1_k127_1451855_50 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 394.0
HKD1_k127_1451855_51 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 383.0
HKD1_k127_1451855_52 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 370.0
HKD1_k127_1451855_53 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 366.0
HKD1_k127_1451855_54 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 357.0
HKD1_k127_1451855_55 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 341.0
HKD1_k127_1451855_56 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 322.0
HKD1_k127_1451855_57 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 317.0
HKD1_k127_1451855_58 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 301.0
HKD1_k127_1451855_59 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 281.0
HKD1_k127_1451855_6 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 7e-323 994.0
HKD1_k127_1451855_60 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002426 263.0
HKD1_k127_1451855_61 PFAM nuclease (SNase domain protein) K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
HKD1_k127_1451855_62 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
HKD1_k127_1451855_63 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
HKD1_k127_1451855_64 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000002806 241.0
HKD1_k127_1451855_65 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000000000000000000000000000000000000000000000005429 238.0
HKD1_k127_1451855_66 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001138 254.0
HKD1_k127_1451855_67 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000001426 229.0
HKD1_k127_1451855_68 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000000000000000000000000000000000000000002834 207.0
HKD1_k127_1451855_69 phosphorelay signal transduction system K15012 - - 0.000000000000000000000000000000000000000000000000000000002531 213.0
HKD1_k127_1451855_7 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 8.46e-274 846.0
HKD1_k127_1451855_70 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000009118 193.0
HKD1_k127_1451855_72 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000007836 184.0
HKD1_k127_1451855_74 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000000000000000000000000000000000000000004924 181.0
HKD1_k127_1451855_75 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000006532 196.0
HKD1_k127_1451855_77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000005622 170.0
HKD1_k127_1451855_78 - - - - 0.000000000000000000000000000000000000000000002055 171.0
HKD1_k127_1451855_79 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000000000000000000001938 167.0
HKD1_k127_1451855_8 Histidine kinase K02482 - 2.7.13.3 7.166e-273 850.0
HKD1_k127_1451855_80 beta-lactamase - - - 0.000000000000000000000000000000000000000003459 180.0
HKD1_k127_1451855_82 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000001108 141.0
HKD1_k127_1451855_84 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000003096 128.0
HKD1_k127_1451855_86 Helix-turn-helix domain - - - 0.00000000000000000000000000001042 120.0
HKD1_k127_1451855_87 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000000000000001179 113.0
HKD1_k127_1451855_9 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 2.877e-260 806.0
HKD1_k127_1451855_91 - - - - 0.00005036 45.0
HKD1_k127_1468807_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1786.0
HKD1_k127_1468807_1 His Kinase A (phosphoacceptor) domain - - - 0.0 1548.0
HKD1_k127_1468807_10 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 570.0
HKD1_k127_1468807_11 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 567.0
HKD1_k127_1468807_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 518.0
HKD1_k127_1468807_13 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 553.0
HKD1_k127_1468807_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 509.0
HKD1_k127_1468807_15 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 482.0
HKD1_k127_1468807_16 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 374.0
HKD1_k127_1468807_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 318.0
HKD1_k127_1468807_18 methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
HKD1_k127_1468807_19 protein histidine kinase activity K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001358 290.0
HKD1_k127_1468807_2 ATP-binding region, ATPase domain protein - - - 0.0 1340.0
HKD1_k127_1468807_20 SH3 domain (SH3b1 type) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002278 265.0
HKD1_k127_1468807_21 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000001115 229.0
HKD1_k127_1468807_22 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000004682 244.0
HKD1_k127_1468807_23 Transcriptional regulator K18136 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001556 218.0
HKD1_k127_1468807_24 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000009394 200.0
HKD1_k127_1468807_25 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000000000003155 170.0
HKD1_k127_1468807_26 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000002265 171.0
HKD1_k127_1468807_28 chromate transporter K07240 - - 0.00000000000000000000000000000007464 132.0
HKD1_k127_1468807_29 Polymorphic membrane protein, Chlamydia - - - 0.000000000000000000000008263 120.0
HKD1_k127_1468807_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1217.0
HKD1_k127_1468807_30 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.00004269 48.0
HKD1_k127_1468807_4 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0 1024.0
HKD1_k127_1468807_5 PFAM Extracellular solute-binding protein, family 3 - - - 1.247e-254 797.0
HKD1_k127_1468807_6 Cytochrome c bacterial - - - 5.058e-238 742.0
HKD1_k127_1468807_7 response regulator - - - 9.193e-238 745.0
HKD1_k127_1468807_8 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07792 - - 1.438e-220 692.0
HKD1_k127_1468807_9 cheY-homologous receiver domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 581.0
HKD1_k127_1626068_0 Histidine kinase - - - 5.176e-309 965.0
HKD1_k127_1626068_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.621e-260 809.0
HKD1_k127_1626068_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 319.0
HKD1_k127_1626068_11 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000852 276.0
HKD1_k127_1626068_12 antibiotic catabolic process K13277,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005769 268.0
HKD1_k127_1626068_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
HKD1_k127_1626068_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
HKD1_k127_1626068_15 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000003393 197.0
HKD1_k127_1626068_16 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000000000000000000000000001958 188.0
HKD1_k127_1626068_17 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000003194 162.0
HKD1_k127_1626068_18 - - - - 0.0000000000000000000000000000000000000007976 150.0
HKD1_k127_1626068_19 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000001148 117.0
HKD1_k127_1626068_2 TIGRFAM MATE efflux family protein K03327 - - 7.967e-234 730.0
HKD1_k127_1626068_20 - - - - 0.00000000000000000000000001277 120.0
HKD1_k127_1626068_23 fibronectin type III domain protein - - - 0.000000000001025 70.0
HKD1_k127_1626068_24 light absorption K01297,K01607,K06893 - 3.4.17.13,4.1.1.44 0.000000000001608 74.0
HKD1_k127_1626068_25 TPR repeat - - - 0.00000000001048 75.0
HKD1_k127_1626068_28 Phosphoribosyl transferase domain K07100 - - 0.00002798 48.0
HKD1_k127_1626068_3 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 615.0
HKD1_k127_1626068_4 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 602.0
HKD1_k127_1626068_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 584.0
HKD1_k127_1626068_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 426.0
HKD1_k127_1626068_7 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 419.0
HKD1_k127_1626068_8 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 405.0
HKD1_k127_1626068_9 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
HKD1_k127_1680209_0 response regulator K07712 - - 6.072e-286 883.0
HKD1_k127_1680209_1 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 391.0
HKD1_k127_1680209_2 Isochorismatase family - - - 0.00000000001654 64.0
HKD1_k127_1807707_0 PFAM chemotaxis sensory transducer - - - 1.79e-222 703.0
HKD1_k127_1807707_1 4Fe-4S binding domain - - - 6.728e-194 613.0
HKD1_k127_197600_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 3259.0
HKD1_k127_197600_1 GGDEF domain containing protein - - - 0.0 1223.0
HKD1_k127_197600_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 3.746e-249 775.0
HKD1_k127_197600_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.651e-248 773.0
HKD1_k127_197600_12 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 5.777e-240 751.0
HKD1_k127_197600_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 5.75e-229 717.0
HKD1_k127_197600_14 PFAM Xanthine uracil vitamin C permease K02824 - - 5.466e-227 715.0
HKD1_k127_197600_16 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.961e-222 692.0
HKD1_k127_197600_17 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.611e-216 673.0
HKD1_k127_197600_18 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 1.294e-210 665.0
HKD1_k127_197600_19 Belongs to the ALAD family K01698 - 4.2.1.24 1.512e-210 656.0
HKD1_k127_197600_2 elongation factor Tu domain 2 protein K06207 - - 0.0 1129.0
HKD1_k127_197600_20 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 6.375e-210 659.0
HKD1_k127_197600_21 Peptidoglycan polymerase that is essential for cell division K03588 - - 7.456e-208 650.0
HKD1_k127_197600_22 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 7.299e-205 644.0
HKD1_k127_197600_23 Beta-lactamase superfamily domain K00784 - 3.1.26.11 1.237e-194 610.0
HKD1_k127_197600_24 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 608.0
HKD1_k127_197600_25 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 577.0
HKD1_k127_197600_26 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 569.0
HKD1_k127_197600_27 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 577.0
HKD1_k127_197600_28 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 565.0
HKD1_k127_197600_29 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 560.0
HKD1_k127_197600_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0 1047.0
HKD1_k127_197600_30 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 512.0
HKD1_k127_197600_31 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 499.0
HKD1_k127_197600_32 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
HKD1_k127_197600_33 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 470.0
HKD1_k127_197600_34 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 438.0
HKD1_k127_197600_35 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 427.0
HKD1_k127_197600_36 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 415.0
HKD1_k127_197600_37 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 397.0
HKD1_k127_197600_38 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 379.0
HKD1_k127_197600_39 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 379.0
HKD1_k127_197600_4 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 0.0 1011.0
HKD1_k127_197600_40 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 371.0
HKD1_k127_197600_41 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 372.0
HKD1_k127_197600_42 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
HKD1_k127_197600_43 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 356.0
HKD1_k127_197600_44 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 349.0
HKD1_k127_197600_45 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 335.0
HKD1_k127_197600_46 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 333.0
HKD1_k127_197600_47 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 299.0
HKD1_k127_197600_48 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 296.0
HKD1_k127_197600_49 Histidine kinase K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 297.0
HKD1_k127_197600_5 Chemotaxis sensory transducer K03406 - - 3.597e-320 992.0
HKD1_k127_197600_51 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
HKD1_k127_197600_52 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002821 250.0
HKD1_k127_197600_53 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
HKD1_k127_197600_54 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000000000000000000000001101 221.0
HKD1_k127_197600_55 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000000000000000000000439 215.0
HKD1_k127_197600_56 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
HKD1_k127_197600_57 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
HKD1_k127_197600_58 - - - - 0.0000000000000000000000000000000000000000000000000000000001175 209.0
HKD1_k127_197600_59 - - - - 0.000000000000000000000000000000000000000000000000000000002168 200.0
HKD1_k127_197600_6 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.941e-279 867.0
HKD1_k127_197600_60 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000296 201.0
HKD1_k127_197600_61 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000001194 204.0
HKD1_k127_197600_62 Cell division protein FtsL - - - 0.0000000000000000000000000000000000000000000000000335 180.0
HKD1_k127_197600_64 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000000000000000000000000000000002069 164.0
HKD1_k127_197600_65 Nucleotidyltransferase substrate binding protein like - - - 0.00000000000000000000000000000000000003695 149.0
HKD1_k127_197600_66 PFAM RNA-binding S4 domain protein K14761 - - 0.00000000000000000000000000000000788 128.0
HKD1_k127_197600_67 - - - - 0.0000000000000000000000001099 108.0
HKD1_k127_197600_68 - - - - 0.000000000000000000327 88.0
HKD1_k127_197600_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.911e-269 833.0
HKD1_k127_197600_70 - - - - 0.000000003693 64.0
HKD1_k127_197600_71 helicase domain protein - - - 0.000000008401 60.0
HKD1_k127_197600_72 - - - - 0.00000009054 53.0
HKD1_k127_197600_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 4.757e-256 797.0
HKD1_k127_197600_9 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.998e-255 788.0
HKD1_k127_1984339_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 509.0
HKD1_k127_1984339_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 499.0
HKD1_k127_1984339_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 370.0
HKD1_k127_1984339_4 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000000000000000000000001854 210.0
HKD1_k127_1998076_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1691.0
HKD1_k127_1998076_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1640.0
HKD1_k127_1998076_10 4Fe-4S dicluster domain - - - 2.446e-290 905.0
HKD1_k127_1998076_11 Tfp pilus assembly protein tip-associated adhesin K02674 - - 9.666e-281 949.0
HKD1_k127_1998076_12 Sodium:solute symporter family K14393 - - 1.145e-266 827.0
HKD1_k127_1998076_13 Domains REC, sigma54 interaction, HTH8 - - - 2.426e-266 824.0
HKD1_k127_1998076_14 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 6.421e-263 816.0
HKD1_k127_1998076_15 Ammonium Transporter K03320 - - 4.185e-261 812.0
HKD1_k127_1998076_16 Ammonium Transporter Family K03320 - - 2.784e-246 771.0
HKD1_k127_1998076_17 electron transfer flavoprotein, alpha subunit K03522 - - 1.571e-238 743.0
HKD1_k127_1998076_19 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 4.403e-204 640.0
HKD1_k127_1998076_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1213.0
HKD1_k127_1998076_20 Belongs to the ompA family K03286 - - 1.6e-199 632.0
HKD1_k127_1998076_21 Putative nucleotidyltransferase substrate binding domain K07182 - - 6.769e-197 620.0
HKD1_k127_1998076_22 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 672.0
HKD1_k127_1998076_23 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 603.0
HKD1_k127_1998076_24 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 596.0
HKD1_k127_1998076_25 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 594.0
HKD1_k127_1998076_26 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 585.0
HKD1_k127_1998076_27 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 587.0
HKD1_k127_1998076_28 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 552.0
HKD1_k127_1998076_29 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 547.0
HKD1_k127_1998076_3 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0 1123.0
HKD1_k127_1998076_30 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 530.0
HKD1_k127_1998076_31 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 546.0
HKD1_k127_1998076_32 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 509.0
HKD1_k127_1998076_33 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 485.0
HKD1_k127_1998076_34 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD1_k127_1998076_35 Conserved protein K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 459.0
HKD1_k127_1998076_36 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 462.0
HKD1_k127_1998076_37 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
HKD1_k127_1998076_38 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 454.0
HKD1_k127_1998076_39 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 437.0
HKD1_k127_1998076_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0 1122.0
HKD1_k127_1998076_40 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 423.0
HKD1_k127_1998076_41 signal-transduction protein containing cAMP-binding and CBS domains K02342,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 417.0
HKD1_k127_1998076_42 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 402.0
HKD1_k127_1998076_43 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 406.0
HKD1_k127_1998076_44 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 384.0
HKD1_k127_1998076_45 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 379.0
HKD1_k127_1998076_46 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 379.0
HKD1_k127_1998076_47 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 372.0
HKD1_k127_1998076_48 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 351.0
HKD1_k127_1998076_49 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 346.0
HKD1_k127_1998076_5 4Fe-4S dicluster domain - - - 0.0 1118.0
HKD1_k127_1998076_50 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
HKD1_k127_1998076_51 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 305.0
HKD1_k127_1998076_52 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 298.0
HKD1_k127_1998076_53 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 280.0
HKD1_k127_1998076_54 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002285 318.0
HKD1_k127_1998076_55 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005281 281.0
HKD1_k127_1998076_56 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
HKD1_k127_1998076_57 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002236 252.0
HKD1_k127_1998076_58 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000455 254.0
HKD1_k127_1998076_59 THUMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001763 239.0
HKD1_k127_1998076_6 Sodium:solute symporter family K14393 - - 0.0 1075.0
HKD1_k127_1998076_60 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000192 244.0
HKD1_k127_1998076_61 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
HKD1_k127_1998076_62 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000001237 216.0
HKD1_k127_1998076_63 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000000000000000000000000000002157 211.0
HKD1_k127_1998076_64 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD1_k127_1998076_65 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000000004952 206.0
HKD1_k127_1998076_66 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 209.0
HKD1_k127_1998076_68 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000000003553 183.0
HKD1_k127_1998076_69 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000005087 183.0
HKD1_k127_1998076_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0 1065.0
HKD1_k127_1998076_70 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000002887 178.0
HKD1_k127_1998076_71 Sulfatase - - - 0.000000000000000000000000000000000000000000000001419 194.0
HKD1_k127_1998076_73 - - - - 0.0000000000000000000000000000000000000000000009947 175.0
HKD1_k127_1998076_74 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000000000000000000002871 167.0
HKD1_k127_1998076_75 Cache 3/Cache 2 fusion domain - - - 0.0000000000000000000000000000000000000000001738 180.0
HKD1_k127_1998076_76 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000003745 160.0
HKD1_k127_1998076_77 Putative regulatory protein - - - 0.00000000000000000000000000000000000001816 144.0
HKD1_k127_1998076_78 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000002443 150.0
HKD1_k127_1998076_79 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000008373 142.0
HKD1_k127_1998076_8 AcrB/AcrD/AcrF family K03296,K19594 - - 1.727e-309 962.0
HKD1_k127_1998076_80 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000001415 136.0
HKD1_k127_1998076_81 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000004714 145.0
HKD1_k127_1998076_82 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000007664 122.0
HKD1_k127_1998076_84 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000002173 118.0
HKD1_k127_1998076_85 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000006366 110.0
HKD1_k127_1998076_86 - - - - 0.0000000000000000002923 90.0
HKD1_k127_1998076_87 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000003455 86.0
HKD1_k127_1998076_88 Pfam:N_methyl_2 K02671 - - 0.00000000001005 70.0
HKD1_k127_1998076_9 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.463e-293 924.0
HKD1_k127_1998076_92 IPT/TIG domain - - - 0.0000002363 66.0
HKD1_k127_1998076_94 Prokaryotic N-terminal methylation motif - - - 0.000001045 55.0
HKD1_k127_2036167_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1350.0
HKD1_k127_2036167_1 ImcF-related N-terminal domain K11891 - - 0.0 1066.0
HKD1_k127_2036167_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 589.0
HKD1_k127_2036167_11 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 585.0
HKD1_k127_2036167_12 Carboxypeptidase Taq (M32) metallopeptidase K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 576.0
HKD1_k127_2036167_13 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 529.0
HKD1_k127_2036167_14 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase K01910 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008771,GO:0009987,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 6.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 488.0
HKD1_k127_2036167_15 Phosphoadenosine phosphosulfate reductase K19170 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 482.0
HKD1_k127_2036167_16 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 471.0
HKD1_k127_2036167_17 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 445.0
HKD1_k127_2036167_18 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 435.0
HKD1_k127_2036167_19 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 422.0
HKD1_k127_2036167_2 Citrate lyase alpha subunit K01643 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 7.076e-293 903.0
HKD1_k127_2036167_20 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 419.0
HKD1_k127_2036167_21 AAA domain K19171 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 402.0
HKD1_k127_2036167_22 DNA-sulfur modification-associated K19169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 364.0
HKD1_k127_2036167_23 ATP:dephospho-CoA triphosphoribosyl transferase K05966,K13930 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 355.0
HKD1_k127_2036167_24 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 351.0
HKD1_k127_2036167_25 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 352.0
HKD1_k127_2036167_26 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 339.0
HKD1_k127_2036167_27 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
HKD1_k127_2036167_28 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 318.0
HKD1_k127_2036167_29 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 295.0
HKD1_k127_2036167_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.309e-291 907.0
HKD1_k127_2036167_30 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 325.0
HKD1_k127_2036167_31 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 301.0
HKD1_k127_2036167_32 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009657 300.0
HKD1_k127_2036167_33 AAA domain K19171 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004062 285.0
HKD1_k127_2036167_34 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000419 279.0
HKD1_k127_2036167_35 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
HKD1_k127_2036167_36 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001134 245.0
HKD1_k127_2036167_37 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000005279 238.0
HKD1_k127_2036167_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000006302 228.0
HKD1_k127_2036167_39 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000000000000000002032 210.0
HKD1_k127_2036167_4 secondary active sulfate transmembrane transporter activity K06901 - - 8.014e-277 856.0
HKD1_k127_2036167_40 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000007835 209.0
HKD1_k127_2036167_41 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000000000000000000000000000000006247 193.0
HKD1_k127_2036167_42 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849,K12982 - - 0.00000000000000000000000000000000000000000000000000000369 207.0
HKD1_k127_2036167_43 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000001042 183.0
HKD1_k127_2036167_44 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000009304 177.0
HKD1_k127_2036167_45 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000001528 151.0
HKD1_k127_2036167_46 - - - - 0.00000000000000000000000000000000000006023 147.0
HKD1_k127_2036167_47 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.000000000000000000000000000000000006985 139.0
HKD1_k127_2036167_48 Type VI secretion - - - 0.00000000000000000000000000000001439 138.0
HKD1_k127_2036167_49 electron transfer activity K05337 - - 0.00000000000000000000000000155 115.0
HKD1_k127_2036167_5 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 2.211e-256 799.0
HKD1_k127_2036167_52 Transposase IS200 like - - - 0.0000000000000000000004294 99.0
HKD1_k127_2036167_53 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000384 92.0
HKD1_k127_2036167_54 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016772,GO:0016779,GO:0018065,GO:0018193,GO:0018209,GO:0018246,GO:0018247,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050519,GO:0055114,GO:0071704,GO:1901564 2.7.7.61 0.000000000000000001347 91.0
HKD1_k127_2036167_55 DNA sulphur modification protein DndE K19172 - - 0.000000000000000002092 90.0
HKD1_k127_2036167_57 - - - - 0.0000000001514 63.0
HKD1_k127_2036167_58 SMART Chromosomal replication initiator DnaA domain - - - 0.000000003913 58.0
HKD1_k127_2036167_6 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 5.696e-222 693.0
HKD1_k127_2036167_60 - - - - 0.0006911 42.0
HKD1_k127_2036167_7 PFAM Patatin K07001 - - 7.712e-219 690.0
HKD1_k127_2036167_8 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 2.149e-207 658.0
HKD1_k127_2036167_9 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 612.0
HKD1_k127_2073949_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 0.0 1086.0
HKD1_k127_2073949_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0 1002.0
HKD1_k127_2073949_10 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 456.0
HKD1_k127_2073949_11 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 452.0
HKD1_k127_2073949_12 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 387.0
HKD1_k127_2073949_13 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 301.0
HKD1_k127_2073949_14 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 293.0
HKD1_k127_2073949_15 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006983 277.0
HKD1_k127_2073949_16 nucleotidyltransferase substrate binding protein, HI0074 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004782 241.0
HKD1_k127_2073949_17 regulatory protein IclR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002615 246.0
HKD1_k127_2073949_18 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
HKD1_k127_2073949_19 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
HKD1_k127_2073949_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.48e-321 997.0
HKD1_k127_2073949_20 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000001159 168.0
HKD1_k127_2073949_21 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000001424 145.0
HKD1_k127_2073949_22 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000001717 133.0
HKD1_k127_2073949_23 Nucleotidyltransferase domain K07076 - - 0.0000000000000000000000000001977 117.0
HKD1_k127_2073949_24 - - - - 0.000000000000000000000952 102.0
HKD1_k127_2073949_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000002822 74.0
HKD1_k127_2073949_29 - - - - 0.00003493 50.0
HKD1_k127_2073949_3 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 4.646e-313 964.0
HKD1_k127_2073949_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.645e-292 899.0
HKD1_k127_2073949_5 acetyl-CoA hydrolase transferase K18288 - - 1.715e-239 754.0
HKD1_k127_2073949_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.166e-235 734.0
HKD1_k127_2073949_7 Bacterial regulatory protein, Fis family K21405 - - 1.559e-233 737.0
HKD1_k127_2073949_8 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 1.56e-218 683.0
HKD1_k127_2073949_9 peptidase M42 family protein - - - 1.834e-197 619.0
HKD1_k127_2091294_0 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.0 1346.0
HKD1_k127_2091294_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.7e-314 974.0
HKD1_k127_2091294_10 NAD(P)-binding Rossmann-like domain - - - 1.844e-207 655.0
HKD1_k127_2091294_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 6.851e-206 649.0
HKD1_k127_2091294_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.883e-196 615.0
HKD1_k127_2091294_13 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 608.0
HKD1_k127_2091294_14 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 610.0
HKD1_k127_2091294_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 576.0
HKD1_k127_2091294_16 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 560.0
HKD1_k127_2091294_17 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 563.0
HKD1_k127_2091294_18 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 496.0
HKD1_k127_2091294_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 2.714e-305 955.0
HKD1_k127_2091294_20 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 520.0
HKD1_k127_2091294_21 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 471.0
HKD1_k127_2091294_22 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 463.0
HKD1_k127_2091294_23 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 463.0
HKD1_k127_2091294_24 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 451.0
HKD1_k127_2091294_25 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 448.0
HKD1_k127_2091294_26 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 434.0
HKD1_k127_2091294_27 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 433.0
HKD1_k127_2091294_28 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
HKD1_k127_2091294_29 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 441.0
HKD1_k127_2091294_3 cellulose binding - - - 1.548e-297 944.0
HKD1_k127_2091294_30 GPR1 FUN34 yaaH family protein K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 394.0
HKD1_k127_2091294_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 393.0
HKD1_k127_2091294_32 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 384.0
HKD1_k127_2091294_33 formate dehydrogenase K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
HKD1_k127_2091294_34 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
HKD1_k127_2091294_35 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 331.0
HKD1_k127_2091294_36 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 342.0
HKD1_k127_2091294_37 response regulator K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 313.0
HKD1_k127_2091294_39 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007617 273.0
HKD1_k127_2091294_4 TIGRFAM cytochrome C family protein - - - 1.556e-259 849.0
HKD1_k127_2091294_40 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008459 306.0
HKD1_k127_2091294_41 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
HKD1_k127_2091294_42 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
HKD1_k127_2091294_43 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HKD1_k127_2091294_44 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003573 254.0
HKD1_k127_2091294_45 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008509 266.0
HKD1_k127_2091294_47 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00000000000000000000000000000000000000000000000000000000000007326 234.0
HKD1_k127_2091294_48 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000059 213.0
HKD1_k127_2091294_49 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000345 208.0
HKD1_k127_2091294_5 response regulator - - - 2.003e-250 781.0
HKD1_k127_2091294_50 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000008471 209.0
HKD1_k127_2091294_51 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000001187 207.0
HKD1_k127_2091294_52 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000000000000000000254 196.0
HKD1_k127_2091294_53 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000002501 194.0
HKD1_k127_2091294_54 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000001996 193.0
HKD1_k127_2091294_55 MarR family transcriptional K15973 - - 0.00000000000000000000000000000000000000000000000001539 184.0
HKD1_k127_2091294_56 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000006087 192.0
HKD1_k127_2091294_58 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000000006829 175.0
HKD1_k127_2091294_6 PFAM major facilitator superfamily MFS_1 K08177 - - 1.64e-244 759.0
HKD1_k127_2091294_62 HicB family - - - 0.00000000000000000000000000000000000000000001617 163.0
HKD1_k127_2091294_63 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000002318 163.0
HKD1_k127_2091294_64 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000000000000000000000000005315 179.0
HKD1_k127_2091294_65 response regulator - - - 0.000000000000000000000000000000000000000007564 164.0
HKD1_k127_2091294_66 - - - - 0.0000000000000000000000000000000000000000132 156.0
HKD1_k127_2091294_67 ATP-independent chaperone mediated protein folding K06006 - - 0.000000000000000000000000000000001765 136.0
HKD1_k127_2091294_69 - - - - 0.0000000000000000000000000000009154 124.0
HKD1_k127_2091294_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.949e-216 682.0
HKD1_k127_2091294_70 electron transfer activity K05337 - - 0.000000000000000000000000000003005 120.0
HKD1_k127_2091294_71 Acyl carrier protein - - - 0.0000000000000000000000000000797 122.0
HKD1_k127_2091294_75 - - - - 0.0000000000000000000004222 96.0
HKD1_k127_2091294_77 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000255 79.0
HKD1_k127_2091294_79 - - - - 0.000000008232 58.0
HKD1_k127_2091294_8 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 1.135e-215 669.0
HKD1_k127_2091294_83 small metal-binding protein - - - 0.00002354 48.0
HKD1_k127_2091294_84 Histidine kinase-like ATPases K04079 - - 0.0001412 55.0
HKD1_k127_2091294_9 Histidine kinase - - - 1.305e-212 671.0
HKD1_k127_2137951_0 PFAM alpha amylase catalytic region - - - 9.491e-269 837.0
HKD1_k127_2137951_1 Belongs to the peptidase M16 family - - - 3.328e-265 822.0
HKD1_k127_2137951_2 PFAM peptidase M16 domain protein - - - 8.909e-218 687.0
HKD1_k127_2137951_3 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 464.0
HKD1_k127_2137951_4 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 461.0
HKD1_k127_2137951_5 PFAM PfkB domain protein K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 352.0
HKD1_k127_2137951_6 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000003029 211.0
HKD1_k127_2137951_8 Transposase IS200 like K07491 - - 0.000000005532 59.0
HKD1_k127_2216065_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 2106.0
HKD1_k127_2216065_1 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 0.0 1579.0
HKD1_k127_2216065_10 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 560.0
HKD1_k127_2216065_11 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 532.0
HKD1_k127_2216065_12 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 487.0
HKD1_k127_2216065_13 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
HKD1_k127_2216065_14 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 446.0
HKD1_k127_2216065_15 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 433.0
HKD1_k127_2216065_16 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 425.0
HKD1_k127_2216065_17 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 417.0
HKD1_k127_2216065_18 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 395.0
HKD1_k127_2216065_19 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 387.0
HKD1_k127_2216065_2 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1412.0
HKD1_k127_2216065_20 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 346.0
HKD1_k127_2216065_21 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 339.0
HKD1_k127_2216065_22 - - - - 0.00000000000000000000000000000000000000000000000000005704 193.0
HKD1_k127_2216065_23 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000002726 173.0
HKD1_k127_2216065_24 general secretion pathway protein K10927 - - 0.000000000000000000000000000000000000007654 153.0
HKD1_k127_2216065_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0 1320.0
HKD1_k127_2216065_4 - - - - 0.0 1095.0
HKD1_k127_2216065_5 Domains REC, sigma54 interaction, HTH8 - - - 3.325e-277 855.0
HKD1_k127_2216065_6 Histidine kinase HAMP - - - 1.573e-271 841.0
HKD1_k127_2216065_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 9.937e-216 673.0
HKD1_k127_2216065_8 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 3.82e-203 654.0
HKD1_k127_2216065_9 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 601.0
HKD1_k127_2239388_0 Psort location CytoplasmicMembrane, score - - - 1.074e-286 896.0
HKD1_k127_2239388_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.741e-261 808.0
HKD1_k127_2239388_10 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000004669 184.0
HKD1_k127_2239388_11 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000000001504 136.0
HKD1_k127_2239388_12 Protein of unknown function (DUF3343) - - - 0.00000000000000000000000000000000004078 135.0
HKD1_k127_2239388_13 - - - - 0.0000000000000000000000000000002497 124.0
HKD1_k127_2239388_15 - - - - 0.00002064 51.0
HKD1_k127_2239388_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 436.0
HKD1_k127_2239388_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 428.0
HKD1_k127_2239388_4 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 371.0
HKD1_k127_2239388_5 SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 310.0
HKD1_k127_2239388_6 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 301.0
HKD1_k127_2239388_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 281.0
HKD1_k127_2239388_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000008122 225.0
HKD1_k127_2239388_9 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000000000000000000000000000113 216.0
HKD1_k127_2250768_0 COG3209 Rhs family protein - - - 0.0 1677.0
HKD1_k127_2250768_1 Baseplate J-like protein - - - 0.0 1515.0
HKD1_k127_2250768_10 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 368.0
HKD1_k127_2250768_11 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 338.0
HKD1_k127_2250768_12 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 356.0
HKD1_k127_2250768_13 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 325.0
HKD1_k127_2250768_14 transcriptional regulator K22108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 318.0
HKD1_k127_2250768_15 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 293.0
HKD1_k127_2250768_16 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007156 273.0
HKD1_k127_2250768_17 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005429 262.0
HKD1_k127_2250768_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 268.0
HKD1_k127_2250768_19 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000000000000000000000000000001501 228.0
HKD1_k127_2250768_2 protein of Photorhabdus and some similarities with - - - 0.0 1319.0
HKD1_k127_2250768_20 GGDEF domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000819 213.0
HKD1_k127_2250768_21 MutT nudix family protein - - - 0.000000000000000000000000000000000000000000000000000000001805 207.0
HKD1_k127_2250768_22 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000003972 147.0
HKD1_k127_2250768_23 PAAR motif - - - 0.00000000000000000000000000000000000005287 145.0
HKD1_k127_2250768_24 - - - - 0.00000000000000000569 85.0
HKD1_k127_2250768_3 Domain of unknown function (DUF4157) - - - 0.0 1206.0
HKD1_k127_2250768_4 Phage late control gene D protein (GPD) - - - 1.768e-280 882.0
HKD1_k127_2250768_5 Phage tail sheath C-terminal domain K06907 - - 7.518e-242 754.0
HKD1_k127_2250768_6 Protein kinase, ABC1 domain-containing - - - 6.733e-240 749.0
HKD1_k127_2250768_7 PFAM AAA ATPase central domain protein - - - 1.223e-199 630.0
HKD1_k127_2250768_8 helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 481.0
HKD1_k127_2250768_9 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 437.0
HKD1_k127_2256204_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1187.0
HKD1_k127_2256204_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.043e-264 815.0
HKD1_k127_2256204_10 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 296.0
HKD1_k127_2256204_11 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
HKD1_k127_2256204_12 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000006896 222.0
HKD1_k127_2256204_13 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000000000000429 134.0
HKD1_k127_2256204_2 Fumarase C C-terminus K01744 - 4.3.1.1 6.051e-238 742.0
HKD1_k127_2256204_3 - - - - 1.069e-226 709.0
HKD1_k127_2256204_4 Phospholipase D. Active site motifs. K06131 - - 4.14e-202 634.0
HKD1_k127_2256204_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 8.272e-199 624.0
HKD1_k127_2256204_6 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 549.0
HKD1_k127_2256204_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 394.0
HKD1_k127_2256204_8 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 351.0
HKD1_k127_2256204_9 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 302.0
HKD1_k127_2356506_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1473.0
HKD1_k127_2356506_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1427.0
HKD1_k127_2356506_10 PFAM phosphoesterase, RecJ domain protein K07462 - - 5.215e-267 831.0
HKD1_k127_2356506_11 May be involved in recombinational repair of damaged DNA K03631 - - 2.497e-252 788.0
HKD1_k127_2356506_12 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 5.294e-243 758.0
HKD1_k127_2356506_13 PFAM AAA ATPase central domain protein K07478 - - 9.282e-242 751.0
HKD1_k127_2356506_14 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 1.257e-238 748.0
HKD1_k127_2356506_15 Neisseria PilC beta-propeller domain K02674 - - 5.269e-235 768.0
HKD1_k127_2356506_16 Type II secretion system (T2SS), protein E, N-terminal domain - - - 5.934e-223 714.0
HKD1_k127_2356506_17 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.796e-221 688.0
HKD1_k127_2356506_18 PFAM FAD dependent oxidoreductase - - - 1.692e-218 682.0
HKD1_k127_2356506_19 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 1.321e-209 653.0
HKD1_k127_2356506_2 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1275.0
HKD1_k127_2356506_20 Peptidase U62 modulator of DNA gyrase K03592 - - 4.443e-197 622.0
HKD1_k127_2356506_21 Natural resistance-associated macrophage protein K03322 - - 3.821e-195 616.0
HKD1_k127_2356506_22 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 609.0
HKD1_k127_2356506_23 Alkaline and neutral invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 603.0
HKD1_k127_2356506_24 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 589.0
HKD1_k127_2356506_25 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 584.0
HKD1_k127_2356506_26 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 561.0
HKD1_k127_2356506_27 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 535.0
HKD1_k127_2356506_28 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823,K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 516.0
HKD1_k127_2356506_29 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 508.0
HKD1_k127_2356506_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1207.0
HKD1_k127_2356506_30 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 504.0
HKD1_k127_2356506_31 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 505.0
HKD1_k127_2356506_32 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 497.0
HKD1_k127_2356506_33 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 494.0
HKD1_k127_2356506_34 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 480.0
HKD1_k127_2356506_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 466.0
HKD1_k127_2356506_36 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 462.0
HKD1_k127_2356506_37 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 438.0
HKD1_k127_2356506_38 Sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 426.0
HKD1_k127_2356506_39 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 408.0
HKD1_k127_2356506_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.0 1049.0
HKD1_k127_2356506_40 Nad-dependent epimerase dehydratase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 400.0
HKD1_k127_2356506_41 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 397.0
HKD1_k127_2356506_42 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 395.0
HKD1_k127_2356506_43 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 378.0
HKD1_k127_2356506_44 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 362.0
HKD1_k127_2356506_45 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 369.0
HKD1_k127_2356506_46 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 340.0
HKD1_k127_2356506_47 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 336.0
HKD1_k127_2356506_48 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
HKD1_k127_2356506_49 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 340.0
HKD1_k127_2356506_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 8.989e-317 974.0
HKD1_k127_2356506_50 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 320.0
HKD1_k127_2356506_51 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 307.0
HKD1_k127_2356506_52 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
HKD1_k127_2356506_53 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 302.0
HKD1_k127_2356506_54 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 284.0
HKD1_k127_2356506_55 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 261.0
HKD1_k127_2356506_56 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 265.0
HKD1_k127_2356506_58 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HKD1_k127_2356506_59 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004231 254.0
HKD1_k127_2356506_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 6.732e-316 986.0
HKD1_k127_2356506_60 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000000000000000000000008556 213.0
HKD1_k127_2356506_61 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000002595 215.0
HKD1_k127_2356506_62 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000000000000000002356 183.0
HKD1_k127_2356506_64 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000009158 169.0
HKD1_k127_2356506_65 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000001527 168.0
HKD1_k127_2356506_66 TIGRFAM Addiction module toxin, Txe YoeB K19158 - - 0.00000000000000000000000000000000000000000000472 164.0
HKD1_k127_2356506_68 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000536 136.0
HKD1_k127_2356506_69 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000923 128.0
HKD1_k127_2356506_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.468e-306 944.0
HKD1_k127_2356506_71 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000000000000009311 117.0
HKD1_k127_2356506_73 Surface antigen - - - 0.00000000000000000004897 98.0
HKD1_k127_2356506_78 - - - - 0.00008963 47.0
HKD1_k127_2356506_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.023e-301 937.0
HKD1_k127_2356506_80 - - - - 0.0001777 46.0
HKD1_k127_2356506_82 Prokaryotic N-terminal methylation motif - - - 0.0009411 50.0
HKD1_k127_2356506_9 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.606e-286 880.0
HKD1_k127_2386440_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 2029.0
HKD1_k127_2386440_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1502.0
HKD1_k127_2386440_10 4Fe-4S dicluster domain - - - 2.558e-307 953.0
HKD1_k127_2386440_100 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
HKD1_k127_2386440_101 TIGRFAM EpsI family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
HKD1_k127_2386440_102 4Fe-4S dicluster domain K00196,K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 290.0
HKD1_k127_2386440_103 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 301.0
HKD1_k127_2386440_104 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD1_k127_2386440_105 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008614 282.0
HKD1_k127_2386440_106 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001169 287.0
HKD1_k127_2386440_107 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003139 291.0
HKD1_k127_2386440_108 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004006 290.0
HKD1_k127_2386440_109 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001101 284.0
HKD1_k127_2386440_11 PFAM ATP-binding region, ATPase domain protein - - - 2.844e-292 911.0
HKD1_k127_2386440_110 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001261 276.0
HKD1_k127_2386440_111 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001025 263.0
HKD1_k127_2386440_112 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 263.0
HKD1_k127_2386440_113 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005882 248.0
HKD1_k127_2386440_115 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000003444 243.0
HKD1_k127_2386440_116 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005196 260.0
HKD1_k127_2386440_117 serine acetyltransferase K00640,K03819 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000002209 258.0
HKD1_k127_2386440_118 Protein of unknown function (DUF642) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007079 239.0
HKD1_k127_2386440_119 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000009464 236.0
HKD1_k127_2386440_12 Aminotransferase class I and II - - - 2.558e-274 846.0
HKD1_k127_2386440_120 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
HKD1_k127_2386440_121 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
HKD1_k127_2386440_122 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001478 239.0
HKD1_k127_2386440_123 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.00000000000000000000000000000000000000000000000000000000000001418 218.0
HKD1_k127_2386440_124 - - - - 0.00000000000000000000000000000000000000000000000000000000000002379 243.0
HKD1_k127_2386440_125 Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane K11941 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0008150,GO:0008152,GO:0009311,GO:0016020,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0044238,GO:0044464,GO:0071704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000008411 228.0
HKD1_k127_2386440_126 Glycosyltransferase like family 2 K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000000000007036 211.0
HKD1_k127_2386440_127 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000001513 216.0
HKD1_k127_2386440_128 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000000000000115 192.0
HKD1_k127_2386440_129 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000002123 197.0
HKD1_k127_2386440_13 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 7.001e-268 837.0
HKD1_k127_2386440_130 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000001605 199.0
HKD1_k127_2386440_131 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000968 201.0
HKD1_k127_2386440_132 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000002742 183.0
HKD1_k127_2386440_133 - - - - 0.000000000000000000000000000000000000000000000002627 173.0
HKD1_k127_2386440_134 transferase activity, transferring amino-acyl groups - - - 0.00000000000000000000000000000000000000000000004497 178.0
HKD1_k127_2386440_135 - - - - 0.0000000000000000000000000000000000000000000001533 171.0
HKD1_k127_2386440_137 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000001266 187.0
HKD1_k127_2386440_138 - - - - 0.00000000000000000000000000000000000000000001282 176.0
HKD1_k127_2386440_139 Domain of unknown function (DUF1904) - - - 0.0000000000000000000000000000000000000000004696 161.0
HKD1_k127_2386440_14 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 1.477e-260 805.0
HKD1_k127_2386440_140 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000000000000000000000000000001893 158.0
HKD1_k127_2386440_141 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000002207 169.0
HKD1_k127_2386440_142 Low affinity iron permease - - - 0.0000000000000000000000000000000000000001098 154.0
HKD1_k127_2386440_143 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.0000000000000000000000000000000000000001143 153.0
HKD1_k127_2386440_144 PKD domain - - - 0.0000000000000000000000000000000000003166 163.0
HKD1_k127_2386440_145 Acetyltransferase - - - 0.000000000000000000000000000000000000774 148.0
HKD1_k127_2386440_146 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000002307 143.0
HKD1_k127_2386440_147 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000008913 134.0
HKD1_k127_2386440_148 nUDIX hydrolase K01515,K03574,K08310 - 3.6.1.13,3.6.1.55,3.6.1.67 0.0000000000000000000000000000000001702 136.0
HKD1_k127_2386440_149 PKD domain - - - 0.0000000000000000000000000000000002143 151.0
HKD1_k127_2386440_15 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.165e-251 785.0
HKD1_k127_2386440_151 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000001738 130.0
HKD1_k127_2386440_152 Rhodanese Homology Domain - - - 0.000000000000000000000000000000002307 134.0
HKD1_k127_2386440_153 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000000003872 125.0
HKD1_k127_2386440_154 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000005287 142.0
HKD1_k127_2386440_155 xylanase chitin deacetylase - - - 0.000000000000000000000000000002102 134.0
HKD1_k127_2386440_157 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000001372 122.0
HKD1_k127_2386440_159 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000003257 127.0
HKD1_k127_2386440_16 Peptidase family M1 domain - - - 3.56e-250 793.0
HKD1_k127_2386440_161 - - - - 0.000000000000000000000009787 106.0
HKD1_k127_2386440_162 Belongs to the peptidase S8 family - - - 0.00000000000000000000004044 113.0
HKD1_k127_2386440_163 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000003225 102.0
HKD1_k127_2386440_164 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000005639 98.0
HKD1_k127_2386440_165 Domain of unknown function (DUF1858) - - - 0.00000000000000000000105 101.0
HKD1_k127_2386440_166 extracellular matrix structural constituent - - - 0.00000000000000009391 95.0
HKD1_k127_2386440_167 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000007082 61.0
HKD1_k127_2386440_168 Chitinase class I K03791 - - 0.000000003655 66.0
HKD1_k127_2386440_17 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 4.111e-247 766.0
HKD1_k127_2386440_171 UbiA prenyltransferase family - - - 0.000002104 50.0
HKD1_k127_2386440_172 GDSL-like Lipase/Acylhydrolase family - - - 0.000003191 59.0
HKD1_k127_2386440_173 O-Antigen ligase - - - 0.000004255 59.0
HKD1_k127_2386440_174 - - - - 0.000004433 51.0
HKD1_k127_2386440_175 fibronectin type III domain protein - - - 0.0001124 46.0
HKD1_k127_2386440_176 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0002987 53.0
HKD1_k127_2386440_179 fibronectin type III domain protein - - - 0.0006291 42.0
HKD1_k127_2386440_18 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 3.173e-240 756.0
HKD1_k127_2386440_19 - - - - 4.662e-239 744.0
HKD1_k127_2386440_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1455.0
HKD1_k127_2386440_20 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 1.103e-236 733.0
HKD1_k127_2386440_21 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 6.321e-233 726.0
HKD1_k127_2386440_22 electron transfer flavoprotein, alpha subunit K03522 - - 5.038e-228 712.0
HKD1_k127_2386440_23 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.443e-225 701.0
HKD1_k127_2386440_24 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 6.987e-223 693.0
HKD1_k127_2386440_25 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 1.34e-221 693.0
HKD1_k127_2386440_26 Proposed homoserine kinase K15635 - 5.4.2.12 1.401e-221 692.0
HKD1_k127_2386440_27 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 6.405e-220 688.0
HKD1_k127_2386440_28 Belongs to the thiolase family K00626 - 2.3.1.9 6.21e-219 690.0
HKD1_k127_2386440_29 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 2.727e-218 694.0
HKD1_k127_2386440_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1290.0
HKD1_k127_2386440_30 Glutamine amidotransferases class-II - - - 1.095e-217 678.0
HKD1_k127_2386440_31 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 3.698e-217 685.0
HKD1_k127_2386440_32 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 4.543e-217 679.0
HKD1_k127_2386440_33 Major Facilitator Superfamily K02429 - - 9.327e-217 679.0
HKD1_k127_2386440_34 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 3.496e-213 668.0
HKD1_k127_2386440_35 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 6.054e-209 655.0
HKD1_k127_2386440_36 Peptidase dimerisation domain K01436 - - 2.621e-206 647.0
HKD1_k127_2386440_37 PFAM aminotransferase class-III K01845 - 5.4.3.8 2.443e-195 617.0
HKD1_k127_2386440_38 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 606.0
HKD1_k127_2386440_39 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 601.0
HKD1_k127_2386440_4 4Fe-4S dicluster domain - - - 0.0 1155.0
HKD1_k127_2386440_40 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 598.0
HKD1_k127_2386440_41 winged helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 586.0
HKD1_k127_2386440_42 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 581.0
HKD1_k127_2386440_43 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 578.0
HKD1_k127_2386440_44 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 557.0
HKD1_k127_2386440_45 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 573.0
HKD1_k127_2386440_46 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 541.0
HKD1_k127_2386440_47 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 514.0
HKD1_k127_2386440_48 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 525.0
HKD1_k127_2386440_49 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 507.0
HKD1_k127_2386440_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1135.0
HKD1_k127_2386440_50 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 505.0
HKD1_k127_2386440_51 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 498.0
HKD1_k127_2386440_52 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 501.0
HKD1_k127_2386440_53 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 477.0
HKD1_k127_2386440_54 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 470.0
HKD1_k127_2386440_55 integrase domain protein SAM domain protein K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 475.0
HKD1_k127_2386440_56 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 458.0
HKD1_k127_2386440_57 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 460.0
HKD1_k127_2386440_58 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 447.0
HKD1_k127_2386440_59 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 441.0
HKD1_k127_2386440_6 TPR repeat-containing protein - - - 0.0 1120.0
HKD1_k127_2386440_60 -O-antigen K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 451.0
HKD1_k127_2386440_61 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 445.0
HKD1_k127_2386440_62 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 447.0
HKD1_k127_2386440_63 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
HKD1_k127_2386440_64 PFAM glutamate synthase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 426.0
HKD1_k127_2386440_65 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 431.0
HKD1_k127_2386440_66 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 430.0
HKD1_k127_2386440_67 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 437.0
HKD1_k127_2386440_68 PFAM Polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 413.0
HKD1_k127_2386440_69 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 413.0
HKD1_k127_2386440_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1046.0
HKD1_k127_2386440_70 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 411.0
HKD1_k127_2386440_71 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 404.0
HKD1_k127_2386440_72 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 413.0
HKD1_k127_2386440_73 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 391.0
HKD1_k127_2386440_74 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 397.0
HKD1_k127_2386440_75 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 390.0
HKD1_k127_2386440_76 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 397.0
HKD1_k127_2386440_77 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 371.0
HKD1_k127_2386440_78 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 382.0
HKD1_k127_2386440_79 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 366.0
HKD1_k127_2386440_8 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.659e-316 971.0
HKD1_k127_2386440_80 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 359.0
HKD1_k127_2386440_81 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 361.0
HKD1_k127_2386440_82 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 378.0
HKD1_k127_2386440_83 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 345.0
HKD1_k127_2386440_84 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 346.0
HKD1_k127_2386440_85 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 348.0
HKD1_k127_2386440_86 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
HKD1_k127_2386440_87 family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 337.0
HKD1_k127_2386440_88 Bifunctional protein PyrR K02825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 335.0
HKD1_k127_2386440_89 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
HKD1_k127_2386440_9 Belongs to the glutamate synthase family K22083 - 2.1.1.21 1.66e-315 970.0
HKD1_k127_2386440_90 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 331.0
HKD1_k127_2386440_91 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 342.0
HKD1_k127_2386440_92 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
HKD1_k127_2386440_93 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 316.0
HKD1_k127_2386440_94 Pfam:Methyltransf_26 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 315.0
HKD1_k127_2386440_95 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 309.0
HKD1_k127_2386440_96 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 312.0
HKD1_k127_2386440_97 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 325.0
HKD1_k127_2386440_98 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 294.0
HKD1_k127_2386440_99 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 305.0
HKD1_k127_2529482_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 6.987e-319 1031.0
HKD1_k127_2529482_1 Berberine and berberine like - - - 2.386e-254 789.0
HKD1_k127_2529482_10 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HKD1_k127_2529482_11 regulatory protein LysR K02019 - - 0.00000000000000000000000000000000000000000000000000000000004952 208.0
HKD1_k127_2529482_12 - - - - 0.000000000000000000000000000000000000000000000000000006359 201.0
HKD1_k127_2529482_13 Putative regulatory protein - - - 0.00000000003732 66.0
HKD1_k127_2529482_14 diguanylate cyclase activity - - - 0.0007318 42.0
HKD1_k127_2529482_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 6.16e-253 782.0
HKD1_k127_2529482_3 Domain of unknown function (DUF4445) - - - 9.078e-228 722.0
HKD1_k127_2529482_4 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 1.179e-224 705.0
HKD1_k127_2529482_5 SMART Elongator protein 3 MiaB NifB - - - 1.393e-211 664.0
HKD1_k127_2529482_6 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 451.0
HKD1_k127_2529482_7 Methionine synthase B12-binding module cap domain protein K00548,K14081,K16179 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 378.0
HKD1_k127_2529482_8 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 307.0
HKD1_k127_2529482_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 314.0
HKD1_k127_2565667_0 CBS domain containing protein K00974 - 2.7.7.72 0.0 1423.0
HKD1_k127_2565667_1 SMART Nucleotide binding protein, PINc K07175 - - 6.304e-257 797.0
HKD1_k127_2565667_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.406e-205 646.0
HKD1_k127_2565667_3 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 591.0
HKD1_k127_2565667_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 589.0
HKD1_k127_2565667_5 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 557.0
HKD1_k127_2565667_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 451.0
HKD1_k127_2565667_7 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 404.0
HKD1_k127_2565667_8 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 307.0
HKD1_k127_2565667_9 - - - - 0.0000000000000000000000000000000005312 134.0
HKD1_k127_2671627_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.75e-292 902.0
HKD1_k127_2671627_1 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 7.063e-264 818.0
HKD1_k127_2671627_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 299.0
HKD1_k127_2671627_11 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
HKD1_k127_2671627_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
HKD1_k127_2671627_13 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000000005247 226.0
HKD1_k127_2671627_14 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006443 224.0
HKD1_k127_2671627_15 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000001919 115.0
HKD1_k127_2671627_16 Glycosyltransferase like family 2 - - - 0.00000000002926 64.0
HKD1_k127_2671627_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.7e-260 809.0
HKD1_k127_2671627_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 1.612e-202 636.0
HKD1_k127_2671627_4 NAD(P)H-binding K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 586.0
HKD1_k127_2671627_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 546.0
HKD1_k127_2671627_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 526.0
HKD1_k127_2671627_7 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 440.0
HKD1_k127_2671627_8 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 442.0
HKD1_k127_2671627_9 COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 441.0
HKD1_k127_2871910_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1097.0
HKD1_k127_2871910_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1013.0
HKD1_k127_2871910_10 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 397.0
HKD1_k127_2871910_11 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
HKD1_k127_2871910_12 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004593 276.0
HKD1_k127_2871910_13 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000003403 233.0
HKD1_k127_2871910_14 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000001212 179.0
HKD1_k127_2871910_15 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD1_k127_2871910_16 STAS domain - - - 0.000000000000000000000000000000000000004656 148.0
HKD1_k127_2871910_18 - - - - 0.000000000000000000000000000008756 119.0
HKD1_k127_2871910_19 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000003768 109.0
HKD1_k127_2871910_2 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 1.276e-236 747.0
HKD1_k127_2871910_20 DNA polymerase - - - 0.00000000000000000000008799 107.0
HKD1_k127_2871910_21 Putative bacterial sensory transduction regulator - - - 0.00000000000006336 78.0
HKD1_k127_2871910_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.941e-227 729.0
HKD1_k127_2871910_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 4.367e-203 638.0
HKD1_k127_2871910_5 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 606.0
HKD1_k127_2871910_6 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 560.0
HKD1_k127_2871910_7 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 509.0
HKD1_k127_2871910_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 500.0
HKD1_k127_2871910_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 451.0
HKD1_k127_3014219_0 Aconitate hydratase 1 K01681 - 4.2.1.3 0.0 1277.0
HKD1_k127_3014219_1 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.0 1241.0
HKD1_k127_3014219_10 SurA N-terminal domain K03770 - 5.2.1.8 1.837e-239 750.0
HKD1_k127_3014219_11 Sigma-54 factor interaction domain-containing protein - - - 2.194e-226 708.0
HKD1_k127_3014219_12 Histidine kinase - - - 1.021e-225 711.0
HKD1_k127_3014219_13 Pyridine nucleotide-disulphide oxidoreductase - - - 8.159e-222 689.0
HKD1_k127_3014219_14 TonB-dependent Receptor Plug K16092 - - 6.242e-215 684.0
HKD1_k127_3014219_15 AIR synthase related protein domain protein K01933 - 6.3.3.1 5.28e-214 666.0
HKD1_k127_3014219_16 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 5.508e-209 651.0
HKD1_k127_3014219_17 SMART Elongator protein 3 MiaB NifB - - - 2.27e-205 648.0
HKD1_k127_3014219_18 belongs to the CobB CobQ family K06873 - - 5.285e-205 642.0
HKD1_k127_3014219_19 PFAM NDP-hexose 23-dehydratase K16435 - 4.2.1.159 6.957e-203 642.0
HKD1_k127_3014219_2 Histidine kinase - - - 0.0 1167.0
HKD1_k127_3014219_20 CHASE4 domain - - - 1.554e-196 637.0
HKD1_k127_3014219_21 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 607.0
HKD1_k127_3014219_22 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 618.0
HKD1_k127_3014219_23 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 619.0
HKD1_k127_3014219_24 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 579.0
HKD1_k127_3014219_25 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 571.0
HKD1_k127_3014219_26 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
HKD1_k127_3014219_27 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 588.0
HKD1_k127_3014219_28 Lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 562.0
HKD1_k127_3014219_29 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 550.0
HKD1_k127_3014219_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.396e-314 969.0
HKD1_k127_3014219_30 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 541.0
HKD1_k127_3014219_31 AAA domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 521.0
HKD1_k127_3014219_32 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 519.0
HKD1_k127_3014219_33 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 512.0
HKD1_k127_3014219_34 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 496.0
HKD1_k127_3014219_35 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 481.0
HKD1_k127_3014219_36 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 462.0
HKD1_k127_3014219_37 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 464.0
HKD1_k127_3014219_38 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
HKD1_k127_3014219_39 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
HKD1_k127_3014219_4 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 6.094e-312 969.0
HKD1_k127_3014219_40 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 433.0
HKD1_k127_3014219_41 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 413.0
HKD1_k127_3014219_42 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 409.0
HKD1_k127_3014219_43 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 421.0
HKD1_k127_3014219_44 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 389.0
HKD1_k127_3014219_45 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 384.0
HKD1_k127_3014219_46 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 359.0
HKD1_k127_3014219_47 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
HKD1_k127_3014219_48 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 347.0
HKD1_k127_3014219_49 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
HKD1_k127_3014219_5 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 6.612e-308 955.0
HKD1_k127_3014219_50 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 331.0
HKD1_k127_3014219_51 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 347.0
HKD1_k127_3014219_52 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
HKD1_k127_3014219_53 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 329.0
HKD1_k127_3014219_54 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 327.0
HKD1_k127_3014219_55 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 306.0
HKD1_k127_3014219_56 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 306.0
HKD1_k127_3014219_57 Membrane-associated sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 324.0
HKD1_k127_3014219_58 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 298.0
HKD1_k127_3014219_59 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 299.0
HKD1_k127_3014219_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.492e-291 909.0
HKD1_k127_3014219_60 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 292.0
HKD1_k127_3014219_61 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 293.0
HKD1_k127_3014219_62 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002419 270.0
HKD1_k127_3014219_63 Metal-dependent phosphohydrolase K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
HKD1_k127_3014219_64 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 261.0
HKD1_k127_3014219_65 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000006199 238.0
HKD1_k127_3014219_66 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
HKD1_k127_3014219_67 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000000000000000004104 202.0
HKD1_k127_3014219_68 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000002599 199.0
HKD1_k127_3014219_69 dnak suppressor protein K06204 - - 0.00000000000000000000000000000000000000000000000000002459 191.0
HKD1_k127_3014219_7 Sodium:sulfate symporter transmembrane region K14445 - - 6.757e-269 832.0
HKD1_k127_3014219_70 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001458 187.0
HKD1_k127_3014219_71 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000396 186.0
HKD1_k127_3014219_72 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000009579 179.0
HKD1_k127_3014219_73 YtxH-like protein - - - 0.0000000000000000000000000000000000000008378 151.0
HKD1_k127_3014219_74 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000000000000000000312 158.0
HKD1_k127_3014219_75 protein conserved in bacteria - - - 0.0000000000000000000000000000002232 128.0
HKD1_k127_3014219_76 homolog of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.00000000000000000000000000006955 119.0
HKD1_k127_3014219_77 SlyX K03745 - - 0.00000000000000000000000003741 108.0
HKD1_k127_3014219_78 YtxH-like protein - - - 0.000000000000000000000000205 107.0
HKD1_k127_3014219_79 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000002621 89.0
HKD1_k127_3014219_8 response regulator - - - 4.204e-262 812.0
HKD1_k127_3014219_82 Dienelactone hydrolase family K06889 - - 0.0000000004693 61.0
HKD1_k127_3014219_83 Hsp20/alpha crystallin family K13993 - - 0.000000004566 59.0
HKD1_k127_3014219_84 Alpha/beta hydrolase family - - - 0.000000261 53.0
HKD1_k127_3014219_85 PFAM WD40 domain protein beta Propeller - - - 0.0000229 48.0
HKD1_k127_3014219_86 - - - - 0.0005772 48.0
HKD1_k127_3014219_9 alpha amylase, catalytic region - - - 4.467e-242 757.0
HKD1_k127_3035586_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1455.0
HKD1_k127_3035586_1 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 509.0
HKD1_k127_3035586_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.000000000000000000000000000000000000000001587 159.0
HKD1_k127_3050954_0 PrkA AAA domain protein - - - 0.0 1379.0
HKD1_k127_3050954_1 Serine protein kinase K07180 - - 0.0 1290.0
HKD1_k127_3050954_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 546.0
HKD1_k127_3050954_11 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 532.0
HKD1_k127_3050954_12 Sodium:dicarboxylate symporter family K03309,K11102,K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 500.0
HKD1_k127_3050954_13 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
HKD1_k127_3050954_14 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
HKD1_k127_3050954_15 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 262.0
HKD1_k127_3050954_19 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000006016 86.0
HKD1_k127_3050954_2 PFAM SpoVR family protein K06415 - - 7.267e-317 977.0
HKD1_k127_3050954_3 DNA polymerase K02347 - - 5.912e-283 881.0
HKD1_k127_3050954_4 Belongs to the UPF0229 family K09786 - - 4.216e-268 829.0
HKD1_k127_3050954_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.476e-230 717.0
HKD1_k127_3050954_6 PFAM Extracellular solute-binding protein, family 3 - - - 9.472e-229 723.0
HKD1_k127_3050954_7 response regulator - - - 8.483e-213 669.0
HKD1_k127_3050954_8 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 613.0
HKD1_k127_3050954_9 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 576.0
HKD1_k127_313288_0 helicase domain protein - - - 0.0 1866.0
HKD1_k127_313288_1 PFAM SNF2-related protein - - - 0.0 1470.0
HKD1_k127_313288_10 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004679 248.0
HKD1_k127_313288_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000009258 222.0
HKD1_k127_313288_13 lactoylglutathione lyase activity K01239,K08234 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000132 198.0
HKD1_k127_313288_14 TIGRFAM addiction module toxin, RelE StbE family K19092 - - 0.000000000000000000000001384 105.0
HKD1_k127_313288_15 - - - - 0.00000000000000004045 84.0
HKD1_k127_313288_16 bacterial-type proximal promoter sequence-specific DNA binding K07473 - - 0.00000001266 61.0
HKD1_k127_313288_2 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 1.273e-287 888.0
HKD1_k127_313288_3 N-terminal domain of unknown function (DUF4140) - - - 7.796e-230 724.0
HKD1_k127_313288_4 - - - - 1.012e-221 695.0
HKD1_k127_313288_5 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 601.0
HKD1_k127_313288_6 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 595.0
HKD1_k127_313288_7 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 528.0
HKD1_k127_313288_8 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 411.0
HKD1_k127_313288_9 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 353.0
HKD1_k127_3197779_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000005792 197.0
HKD1_k127_3197779_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000002747 177.0
HKD1_k127_3197779_2 PFAM Transposase DDE domain - - - 0.00001663 48.0
HKD1_k127_3233502_0 Cytochrome c3 - - - 0.0 1033.0
HKD1_k127_3233502_1 PFAM ABC transporter related - - - 0.0 1006.0
HKD1_k127_3233502_10 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 458.0
HKD1_k127_3233502_11 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 438.0
HKD1_k127_3233502_12 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 409.0
HKD1_k127_3233502_13 response regulator K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 376.0
HKD1_k127_3233502_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 327.0
HKD1_k127_3233502_15 beta-galactosidase activity K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 308.0
HKD1_k127_3233502_16 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 280.0
HKD1_k127_3233502_17 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 276.0
HKD1_k127_3233502_18 DNA-binding transcription factor activity K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009382 282.0
HKD1_k127_3233502_19 PFAM SEC-C motif domain protein K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 258.0
HKD1_k127_3233502_2 response regulator K13599 - - 1.764e-267 826.0
HKD1_k127_3233502_20 PFAM Desulfoferrodoxin, ferrous iron-binding region K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000005132 213.0
HKD1_k127_3233502_21 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000000003083 193.0
HKD1_k127_3233502_22 - - - - 0.000000000000000000000000000000000000000000000000003263 188.0
HKD1_k127_3233502_23 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions - - - 0.00000000000000000000000000000000000000000000004987 174.0
HKD1_k127_3233502_24 PFAM Stress responsive alpha-beta barrel - - - 0.0000000000000000000000000000000000000005002 150.0
HKD1_k127_3233502_25 - - - - 0.000000000000000000000000000000000000003253 149.0
HKD1_k127_3233502_26 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000001488 109.0
HKD1_k127_3233502_3 PFAM aminotransferase, class I and II K11358 - 2.6.1.1 2.855e-227 707.0
HKD1_k127_3233502_4 CBS domain containing protein K03699 - - 1.012e-220 691.0
HKD1_k127_3233502_5 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 2.282e-216 679.0
HKD1_k127_3233502_6 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 9.327e-204 642.0
HKD1_k127_3233502_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 605.0
HKD1_k127_3233502_8 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 610.0
HKD1_k127_3233502_9 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 464.0
HKD1_k127_3275508_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.061e-274 848.0
HKD1_k127_3275508_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.465e-255 788.0
HKD1_k127_3275508_3 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
HKD1_k127_3275508_4 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005767 265.0
HKD1_k127_3275508_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000469 162.0
HKD1_k127_3293527_0 Protein of unknown function (DUF3373) - - - 4.224e-285 884.0
HKD1_k127_3293527_1 Cytochrome c554 and c-prime - - - 5.356e-225 704.0
HKD1_k127_3293527_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 351.0
HKD1_k127_3383202_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 2095.0
HKD1_k127_3383202_1 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.683e-306 958.0
HKD1_k127_3383202_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000002113 141.0
HKD1_k127_3383202_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000002342 75.0
HKD1_k127_3383202_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000009721 65.0
HKD1_k127_3383202_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.993e-254 786.0
HKD1_k127_3383202_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.291e-253 782.0
HKD1_k127_3383202_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 1.952e-240 746.0
HKD1_k127_3383202_5 diguanylate cyclase - - - 5.792e-229 716.0
HKD1_k127_3383202_6 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 529.0
HKD1_k127_3383202_7 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 479.0
HKD1_k127_3383202_8 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 409.0
HKD1_k127_3383202_9 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000036 259.0
HKD1_k127_3395205_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 601.0
HKD1_k127_3395205_2 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 297.0
HKD1_k127_3395205_3 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000003566 169.0
HKD1_k127_3395205_4 Peptidoglycan-binding domain 1 protein K01233 - 3.2.1.132 0.000000001123 68.0
HKD1_k127_3414683_0 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 6.273e-268 839.0
HKD1_k127_3414683_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 606.0
HKD1_k127_3414683_10 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 318.0
HKD1_k127_3414683_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 295.0
HKD1_k127_3414683_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 291.0
HKD1_k127_3414683_14 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 290.0
HKD1_k127_3414683_15 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000000001355 218.0
HKD1_k127_3414683_16 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000003101 196.0
HKD1_k127_3414683_17 - - - - 0.00000000000000000000000000000000000000000000000001041 181.0
HKD1_k127_3414683_18 - - - - 0.0000000000000000000000000000000000000000003925 161.0
HKD1_k127_3414683_19 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000001285 133.0
HKD1_k127_3414683_2 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 592.0
HKD1_k127_3414683_21 AAA domain - - - 0.0000000000002434 72.0
HKD1_k127_3414683_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 552.0
HKD1_k127_3414683_4 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 517.0
HKD1_k127_3414683_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 469.0
HKD1_k127_3414683_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 445.0
HKD1_k127_3414683_7 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
HKD1_k127_3414683_8 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 332.0
HKD1_k127_3414683_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 327.0
HKD1_k127_3472266_0 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0 1745.0
HKD1_k127_3472266_1 PFAM carboxyl transferase - - - 0.0 1039.0
HKD1_k127_3472266_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000007509 224.0
HKD1_k127_3472266_11 Outer membrane protein beta-barrel domain K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
HKD1_k127_3472266_12 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000001436 128.0
HKD1_k127_3472266_17 - - - - 0.00000009516 54.0
HKD1_k127_3472266_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.826e-321 987.0
HKD1_k127_3472266_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.285e-257 796.0
HKD1_k127_3472266_4 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 3.096e-209 661.0
HKD1_k127_3472266_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 1.115e-196 622.0
HKD1_k127_3472266_6 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 458.0
HKD1_k127_3472266_7 Cell surface protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 462.0
HKD1_k127_3472266_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 397.0
HKD1_k127_3472266_9 PFAM ThiJ PfpI domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 351.0
HKD1_k127_348250_0 Glycogen debranching enzyme - - - 7.43e-217 680.0
HKD1_k127_348250_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000001031 91.0
HKD1_k127_3567389_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0 3493.0
HKD1_k127_3567389_1 Fibronectin type 3 domain K20276 - - 0.0 3132.0
HKD1_k127_3567389_10 General secretory system II, protein E domain protein K02652 - - 0.0 1037.0
HKD1_k127_3567389_100 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 317.0
HKD1_k127_3567389_101 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
HKD1_k127_3567389_102 phosphonoacetaldehyde hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 314.0
HKD1_k127_3567389_103 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 300.0
HKD1_k127_3567389_104 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
HKD1_k127_3567389_106 PFAM Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002859 281.0
HKD1_k127_3567389_107 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004264 281.0
HKD1_k127_3567389_109 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
HKD1_k127_3567389_11 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 2e-322 989.0
HKD1_k127_3567389_110 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009939 285.0
HKD1_k127_3567389_111 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 285.0
HKD1_k127_3567389_112 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002716 259.0
HKD1_k127_3567389_113 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008045 260.0
HKD1_k127_3567389_114 PFAM Resolvase K14060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
HKD1_k127_3567389_116 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000004223 246.0
HKD1_k127_3567389_117 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001472 241.0
HKD1_k127_3567389_118 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
HKD1_k127_3567389_119 glycerophosphodiester phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000005831 234.0
HKD1_k127_3567389_12 RNA secondary structure unwinding K03724 - - 2.341e-307 955.0
HKD1_k127_3567389_120 Transcription regulator MerR DNA binding K21902 - - 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
HKD1_k127_3567389_121 - - - - 0.000000000000000000000000000000000000000000000000000000000000000209 226.0
HKD1_k127_3567389_122 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 235.0
HKD1_k127_3567389_124 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000005641 214.0
HKD1_k127_3567389_125 biosynthesis protein E K06139 - - 0.00000000000000000000000000000000000000000000000000000000000005828 227.0
HKD1_k127_3567389_126 - - - - 0.000000000000000000000000000000000000000000000000000000008363 207.0
HKD1_k127_3567389_127 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000000000000000000000000002607 205.0
HKD1_k127_3567389_129 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000000000005432 182.0
HKD1_k127_3567389_13 4Fe-4S dicluster domain - - - 8.785e-300 931.0
HKD1_k127_3567389_130 Type II secretion system protein B K02451 - - 0.000000000000000000000000000000000000000000000000005893 190.0
HKD1_k127_3567389_131 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000008307 178.0
HKD1_k127_3567389_132 WavE lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000000000000333 189.0
HKD1_k127_3567389_133 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000004188 179.0
HKD1_k127_3567389_134 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000000000000009762 180.0
HKD1_k127_3567389_135 PFAM Protein phosphatase K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000002327 178.0
HKD1_k127_3567389_136 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000005131 158.0
HKD1_k127_3567389_138 - - - - 0.000000000000000000000000000000000000000006184 175.0
HKD1_k127_3567389_139 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000002937 175.0
HKD1_k127_3567389_14 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 2.802e-294 912.0
HKD1_k127_3567389_140 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000003622 167.0
HKD1_k127_3567389_141 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001046 150.0
HKD1_k127_3567389_142 - - - - 0.000000000000000000000000000000000001716 147.0
HKD1_k127_3567389_143 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000000008888 122.0
HKD1_k127_3567389_144 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000001553 134.0
HKD1_k127_3567389_145 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000004716 131.0
HKD1_k127_3567389_146 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000008468 118.0
HKD1_k127_3567389_147 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000000135 136.0
HKD1_k127_3567389_148 Polymorphic membrane protein, Chlamydia - - - 0.00000000000000000000000000002814 138.0
HKD1_k127_3567389_149 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000002687 129.0
HKD1_k127_3567389_15 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.057e-293 907.0
HKD1_k127_3567389_150 - - - - 0.000000000000000000000000007016 112.0
HKD1_k127_3567389_151 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000008395 112.0
HKD1_k127_3567389_152 Belongs to the 'phage' integrase family - - - 0.000000000000000000001004 104.0
HKD1_k127_3567389_153 Methyltransferase domain - - - 0.000000000000000000001131 105.0
HKD1_k127_3567389_154 Resolvase, N terminal domain - - - 0.000000000000000000002403 96.0
HKD1_k127_3567389_155 - - - - 0.00000000000000000005648 90.0
HKD1_k127_3567389_156 Phosphopantetheine attachment site - - - 0.00000000000000000008021 96.0
HKD1_k127_3567389_157 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000002313 89.0
HKD1_k127_3567389_158 - - - - 0.000000000000003391 85.0
HKD1_k127_3567389_159 Fn3 associated - - - 0.00000000000006876 87.0
HKD1_k127_3567389_16 Sulfatase - - - 2.128e-288 899.0
HKD1_k127_3567389_160 LVIVD repeat-containing protein - - - 0.0000000000167 79.0
HKD1_k127_3567389_161 - - - - 0.00000000007741 76.0
HKD1_k127_3567389_162 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family - - - 0.00000000008668 66.0
HKD1_k127_3567389_163 ResB protein required for cytochrome c biosynthesis K07399 - - 0.0000000001798 73.0
HKD1_k127_3567389_164 restriction endonuclease K07448 - - 0.0000000003209 68.0
HKD1_k127_3567389_165 PPP5 TPR repeat region K04460 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0005911,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006913,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009506,GO:0009628,GO:0009639,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010017,GO:0010019,GO:0010035,GO:0010038,GO:0010380,GO:0012505,GO:0016020,GO:0016021,GO:0016311,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0023052,GO:0030054,GO:0030176,GO:0031090,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0036211,GO:0042175,GO:0042221,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046686,GO:0046906,GO:0046907,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051169,GO:0051171,GO:0051172,GO:0051179,GO:0051193,GO:0051195,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055044,GO:0065007,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071489,GO:0071704,GO:0090056,GO:0097159,GO:0098827,GO:0104004,GO:0140096,GO:1901363,GO:1901401,GO:1901402,GO:1901463,GO:1901464,GO:1901564,GO:1902325 3.1.3.16 0.000000001178 65.0
HKD1_k127_3567389_166 Glycosyltransferase like family 2 - - - 0.000000001627 71.0
HKD1_k127_3567389_168 Tetratricopeptide TPR_2 repeat protein - - - 0.000000002742 70.0
HKD1_k127_3567389_169 PLD-like domain - - - 0.000000007411 69.0
HKD1_k127_3567389_17 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.873e-282 885.0
HKD1_k127_3567389_170 PBS lyase HEAT-like repeat - - - 0.00000001181 68.0
HKD1_k127_3567389_172 - - - - 0.00000003203 61.0
HKD1_k127_3567389_175 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000033 57.0
HKD1_k127_3567389_177 Helix-turn-helix XRE-family like proteins - - - 0.00002989 55.0
HKD1_k127_3567389_178 TIGRFAM DNA binding domain, excisionase family - - - 0.0000418 49.0
HKD1_k127_3567389_18 Protein of unknown function (DUF2723) - - - 3.735e-277 880.0
HKD1_k127_3567389_180 addiction module antidote protein HigA K21498 - - 0.0002845 44.0
HKD1_k127_3567389_19 PFAM Lytic transglycosylase catalytic K08309 - - 1.955e-276 870.0
HKD1_k127_3567389_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1993.0
HKD1_k127_3567389_20 AAA domain - - - 8.034e-274 914.0
HKD1_k127_3567389_21 SMART Elongator protein 3 MiaB NifB - - - 7.622e-265 818.0
HKD1_k127_3567389_22 domain protein - - - 1.064e-257 806.0
HKD1_k127_3567389_23 MlaD protein K06192 - - 4.957e-254 794.0
HKD1_k127_3567389_24 PFAM Extracellular solute-binding protein, family 3 K02030 - - 3.824e-253 794.0
HKD1_k127_3567389_25 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 2.149e-252 785.0
HKD1_k127_3567389_26 response regulator K02667 - - 3.144e-245 762.0
HKD1_k127_3567389_27 SMART Elongator protein 3 MiaB NifB - - - 6.097e-240 745.0
HKD1_k127_3567389_28 Sigma-54 factor interaction domain-containing protein - - - 2.083e-238 747.0
HKD1_k127_3567389_29 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 7.769e-232 725.0
HKD1_k127_3567389_3 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0 1787.0
HKD1_k127_3567389_30 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 9.93e-230 723.0
HKD1_k127_3567389_31 acyl-coa dehydrogenase K00248 - 1.3.8.1 8.583e-227 704.0
HKD1_k127_3567389_32 SMART AAA ATPase K02450 - - 3.7e-225 709.0
HKD1_k127_3567389_33 PFAM type II secretion system K02653 - - 3.849e-224 699.0
HKD1_k127_3567389_34 Bacterial regulatory protein, Fis family - - - 7.263e-224 700.0
HKD1_k127_3567389_35 twitching motility protein K02669 - - 8.503e-221 687.0
HKD1_k127_3567389_36 acyl-coa dehydrogenase - - - 6.927e-215 675.0
HKD1_k127_3567389_37 Belongs to the thiolase family K00626 - 2.3.1.9 4.619e-214 670.0
HKD1_k127_3567389_38 electron transfer flavoprotein, alpha subunit K03522 - - 1.108e-211 665.0
HKD1_k127_3567389_39 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 2.754e-202 667.0
HKD1_k127_3567389_4 Pfam:Methyltransf_26 - - - 0.0 1662.0
HKD1_k127_3567389_40 PFAM Coenzyme A transferase K01039 - 2.8.3.12 8.705e-202 629.0
HKD1_k127_3567389_41 ABC transporter, permease protein K02004 - - 9.357e-202 642.0
HKD1_k127_3567389_42 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 8.448e-201 627.0
HKD1_k127_3567389_43 cytochrome c biogenesis protein K07399 - - 7.738e-196 624.0
HKD1_k127_3567389_44 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 613.0
HKD1_k127_3567389_45 P-loop Domain of unknown function (DUF2791) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 579.0
HKD1_k127_3567389_46 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 584.0
HKD1_k127_3567389_47 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 583.0
HKD1_k127_3567389_48 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 572.0
HKD1_k127_3567389_49 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 531.0
HKD1_k127_3567389_5 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1375.0
HKD1_k127_3567389_50 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 546.0
HKD1_k127_3567389_51 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 530.0
HKD1_k127_3567389_52 Domain of unknown function(DUF2779) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 537.0
HKD1_k127_3567389_53 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 520.0
HKD1_k127_3567389_54 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 525.0
HKD1_k127_3567389_55 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 518.0
HKD1_k127_3567389_56 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 529.0
HKD1_k127_3567389_57 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 490.0
HKD1_k127_3567389_58 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 494.0
HKD1_k127_3567389_59 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 484.0
HKD1_k127_3567389_6 PglZ domain - - - 0.0 1240.0
HKD1_k127_3567389_60 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 478.0
HKD1_k127_3567389_61 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
HKD1_k127_3567389_62 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 470.0
HKD1_k127_3567389_63 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 461.0
HKD1_k127_3567389_64 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 459.0
HKD1_k127_3567389_65 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 454.0
HKD1_k127_3567389_67 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 452.0
HKD1_k127_3567389_68 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 451.0
HKD1_k127_3567389_69 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 462.0
HKD1_k127_3567389_7 4Fe-4S dicluster domain - - - 0.0 1231.0
HKD1_k127_3567389_70 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 457.0
HKD1_k127_3567389_71 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 473.0
HKD1_k127_3567389_72 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 439.0
HKD1_k127_3567389_73 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 431.0
HKD1_k127_3567389_74 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 482.0
HKD1_k127_3567389_75 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 421.0
HKD1_k127_3567389_76 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 469.0
HKD1_k127_3567389_77 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 417.0
HKD1_k127_3567389_78 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
HKD1_k127_3567389_79 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 436.0
HKD1_k127_3567389_8 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1212.0
HKD1_k127_3567389_80 AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 408.0
HKD1_k127_3567389_81 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
HKD1_k127_3567389_82 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 377.0
HKD1_k127_3567389_83 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 375.0
HKD1_k127_3567389_84 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 415.0
HKD1_k127_3567389_85 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 374.0
HKD1_k127_3567389_86 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 398.0
HKD1_k127_3567389_87 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 371.0
HKD1_k127_3567389_88 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 364.0
HKD1_k127_3567389_89 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 360.0
HKD1_k127_3567389_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1078.0
HKD1_k127_3567389_90 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 355.0
HKD1_k127_3567389_91 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 350.0
HKD1_k127_3567389_92 Domain of unknown function (DUF1788) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 351.0
HKD1_k127_3567389_93 ATPase associated with various cellular activities, AAA_5 K07452 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 361.0
HKD1_k127_3567389_94 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 349.0
HKD1_k127_3567389_95 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HKD1_k127_3567389_96 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 338.0
HKD1_k127_3567389_97 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 331.0
HKD1_k127_3567389_98 PD-(D/E)XK nuclease superfamily K09124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 340.0
HKD1_k127_3567389_99 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 318.0
HKD1_k127_3740743_0 - - - - 0.0 1742.0
HKD1_k127_3740743_1 Amidohydrolase family - - - 8e-323 995.0
HKD1_k127_3740743_2 Belongs to the heat shock protein 70 family K04046 - - 5.899e-231 719.0
HKD1_k127_3740743_3 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 570.0
HKD1_k127_3740743_4 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 436.0
HKD1_k127_3740743_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 463.0
HKD1_k127_3740743_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 408.0
HKD1_k127_3740743_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 333.0
HKD1_k127_3740743_8 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 326.0
HKD1_k127_3740743_9 Antibiotic biosynthesis monooxygenase K09932 - - 0.00000000000000000000000000000000000000000007115 166.0
HKD1_k127_3832017_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1157.0
HKD1_k127_3832017_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 338.0
HKD1_k127_3832017_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000000000000001505 167.0
HKD1_k127_3995828_0 Glycogen debranching enzyme - - - 5.716e-244 756.0
HKD1_k127_4002239_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 524.0
HKD1_k127_4002239_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 383.0
HKD1_k127_4002239_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006805 244.0
HKD1_k127_4002239_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000266 197.0
HKD1_k127_4002239_4 Tetratricopeptide repeat - - - 0.0000000000001598 76.0
HKD1_k127_400661_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1608.0
HKD1_k127_400661_1 Histidine kinase - - - 1e-279 884.0
HKD1_k127_400661_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 2.247e-200 628.0
HKD1_k127_400661_11 TonB dependent receptor K02014 - - 1.441e-195 630.0
HKD1_k127_400661_12 Cytochrome c3 - - - 3.041e-195 612.0
HKD1_k127_400661_13 conserved protein UCP016719 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 590.0
HKD1_k127_400661_14 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 574.0
HKD1_k127_400661_15 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 548.0
HKD1_k127_400661_16 Acetokinase family K00929 - 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 498.0
HKD1_k127_400661_17 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 495.0
HKD1_k127_400661_18 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 505.0
HKD1_k127_400661_19 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 491.0
HKD1_k127_400661_2 - - - - 6.9e-252 801.0
HKD1_k127_400661_20 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 476.0
HKD1_k127_400661_21 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
HKD1_k127_400661_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 466.0
HKD1_k127_400661_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 446.0
HKD1_k127_400661_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 427.0
HKD1_k127_400661_25 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 430.0
HKD1_k127_400661_26 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 421.0
HKD1_k127_400661_27 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 394.0
HKD1_k127_400661_28 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 391.0
HKD1_k127_400661_29 cog0421, spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 378.0
HKD1_k127_400661_3 PAS domain containing protein - - - 9.563e-249 781.0
HKD1_k127_400661_30 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 381.0
HKD1_k127_400661_31 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 358.0
HKD1_k127_400661_32 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HKD1_k127_400661_33 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 300.0
HKD1_k127_400661_34 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 295.0
HKD1_k127_400661_35 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 297.0
HKD1_k127_400661_36 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 290.0
HKD1_k127_400661_37 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 282.0
HKD1_k127_400661_38 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
HKD1_k127_400661_39 retrograde transport, endosome to Golgi K07095 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0022607,GO:0030145,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007653 252.0
HKD1_k127_400661_4 PFAM Rh family protein ammonium transporter K03320 - - 1.239e-241 749.0
HKD1_k127_400661_42 CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000008623 216.0
HKD1_k127_400661_43 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000009848 197.0
HKD1_k127_400661_44 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001019 171.0
HKD1_k127_400661_47 response regulator K02282,K07782,K19135 - - 0.00000000000000000000000000000000000004577 149.0
HKD1_k127_400661_48 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000005322 141.0
HKD1_k127_400661_49 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000002352 128.0
HKD1_k127_400661_5 POTRA domain TamA domain 1 K07277,K07278 - - 2.059e-238 750.0
HKD1_k127_400661_50 - - - - 0.00000000000000000000000000000007968 125.0
HKD1_k127_400661_51 tape measure - - - 0.00000000000000000000000000000009611 136.0
HKD1_k127_400661_54 - - - - 0.0000000000000001468 85.0
HKD1_k127_400661_6 Histone deacetylase domain K04768 - - 1.563e-225 702.0
HKD1_k127_400661_7 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 5.886e-224 705.0
HKD1_k127_400661_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 3.144e-216 677.0
HKD1_k127_400661_9 Serine aminopeptidase, S33 K03928 - 3.1.1.1 5.096e-215 690.0
HKD1_k127_4026053_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 9.464e-226 708.0
HKD1_k127_4026053_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 1.444e-209 668.0
HKD1_k127_4026053_2 Sugar (and other) transporter - - - 5.795e-198 629.0
HKD1_k127_4026053_3 COG1960 Acyl-CoA dehydrogenases K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 583.0
HKD1_k127_4026053_4 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
HKD1_k127_4026053_5 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000008656 270.0
HKD1_k127_4026053_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
HKD1_k127_4026053_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001904 235.0
HKD1_k127_4026053_8 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000002028 101.0
HKD1_k127_4026053_9 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000001471 65.0
HKD1_k127_4028231_0 Resolvase, RNase H domain protein fold K06959 - - 0.0 1257.0
HKD1_k127_4028231_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1142.0
HKD1_k127_4028231_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 474.0
HKD1_k127_4028231_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 427.0
HKD1_k127_4028231_12 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 377.0
HKD1_k127_4028231_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 310.0
HKD1_k127_4028231_14 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 313.0
HKD1_k127_4028231_15 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 301.0
HKD1_k127_4028231_16 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 289.0
HKD1_k127_4028231_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 282.0
HKD1_k127_4028231_18 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003097 277.0
HKD1_k127_4028231_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006382 256.0
HKD1_k127_4028231_2 Gaf domain K03406 - - 0.0 1007.0
HKD1_k127_4028231_20 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
HKD1_k127_4028231_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005912 242.0
HKD1_k127_4028231_22 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000001515 228.0
HKD1_k127_4028231_23 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
HKD1_k127_4028231_24 GIY-YIG catalytic domain - - - 0.000000000000000000000000000000007491 133.0
HKD1_k127_4028231_25 - - - - 0.00000000000000000000000000000001516 128.0
HKD1_k127_4028231_26 PFAM FeoA family protein K04758 - - 0.00000000000000000000000000000002935 128.0
HKD1_k127_4028231_27 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000003317 126.0
HKD1_k127_4028231_28 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000418 123.0
HKD1_k127_4028231_29 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000001641 101.0
HKD1_k127_4028231_3 Fic/DOC family - - - 2.636e-251 779.0
HKD1_k127_4028231_30 PFAM FeoA family protein K04758 - - 0.00000000000000000001308 96.0
HKD1_k127_4028231_31 - - - - 0.0000000000000003142 79.0
HKD1_k127_4028231_33 SNARE associated Golgi protein - - - 0.0001416 44.0
HKD1_k127_4028231_4 amino acid-binding ACT domain protein K00003 - 1.1.1.3 6.675e-249 773.0
HKD1_k127_4028231_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.645e-244 755.0
HKD1_k127_4028231_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 2.438e-200 627.0
HKD1_k127_4028231_7 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 601.0
HKD1_k127_4028231_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 581.0
HKD1_k127_4028231_9 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 536.0
HKD1_k127_4043238_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 576.0
HKD1_k127_4043238_1 Nickel-dependent hydrogenase large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 538.0
HKD1_k127_4043238_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000001034 186.0
HKD1_k127_4043238_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000001944 186.0
HKD1_k127_4043238_12 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000000000000000000259 183.0
HKD1_k127_4043238_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000002629 174.0
HKD1_k127_4043238_15 Carboxypeptidase regulatory-like domain - - - 0.0001179 51.0
HKD1_k127_4043238_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 464.0
HKD1_k127_4043238_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 448.0
HKD1_k127_4043238_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 453.0
HKD1_k127_4043238_5 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 386.0
HKD1_k127_4043238_6 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 344.0
HKD1_k127_4043238_7 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 321.0
HKD1_k127_4043238_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 317.0
HKD1_k127_4043238_9 PFAM PHP domain protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 306.0
HKD1_k127_405287_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1352.0
HKD1_k127_405287_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1074.0
HKD1_k127_405287_10 Type II secretion system K02455,K02653 - - 1.275e-201 633.0
HKD1_k127_405287_11 Type II/IV secretion system protein K02669 - - 1.014e-198 622.0
HKD1_k127_405287_12 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 587.0
HKD1_k127_405287_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 591.0
HKD1_k127_405287_14 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 578.0
HKD1_k127_405287_15 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 542.0
HKD1_k127_405287_16 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 532.0
HKD1_k127_405287_17 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 520.0
HKD1_k127_405287_18 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 514.0
HKD1_k127_405287_19 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 482.0
HKD1_k127_405287_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0 997.0
HKD1_k127_405287_20 PFAM alpha beta hydrolase fold K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 458.0
HKD1_k127_405287_21 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 412.0
HKD1_k127_405287_22 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 383.0
HKD1_k127_405287_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004788 243.0
HKD1_k127_405287_24 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007374 236.0
HKD1_k127_405287_25 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000005045 218.0
HKD1_k127_405287_26 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000000000000000000000000000000000001007 218.0
HKD1_k127_405287_27 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000000000001283 212.0
HKD1_k127_405287_28 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000003994 145.0
HKD1_k127_405287_29 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000000004074 129.0
HKD1_k127_405287_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.179e-259 800.0
HKD1_k127_405287_30 - - - - 0.000000000000000000000000000007275 118.0
HKD1_k127_405287_32 - - - - 0.0000000002598 65.0
HKD1_k127_405287_4 PFAM General secretory system II protein E domain protein - - - 9.534e-249 779.0
HKD1_k127_405287_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 4.606e-247 773.0
HKD1_k127_405287_6 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 3.416e-244 760.0
HKD1_k127_405287_7 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 2.048e-235 731.0
HKD1_k127_405287_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.635e-221 696.0
HKD1_k127_405287_9 Cys/Met metabolism PLP-dependent enzyme - - - 1.126e-212 666.0
HKD1_k127_4069377_0 histidine kinase HAMP region domain protein K03406 - - 0.0 1273.0
HKD1_k127_4069377_1 ABC transporter C-terminal domain K15738 - - 0.0 1084.0
HKD1_k127_4069377_10 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 297.0
HKD1_k127_4069377_11 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 284.0
HKD1_k127_4069377_12 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
HKD1_k127_4069377_13 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
HKD1_k127_4069377_14 - - - - 0.0000000000000000000000000000000000000000000000000000000007536 209.0
HKD1_k127_4069377_16 Protein of unknown function (DUF1294) - - - 0.000000000000000000000000001891 114.0
HKD1_k127_4069377_18 Super-infection exclusion protein B - - - 0.00000000000001396 81.0
HKD1_k127_4069377_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.432e-232 726.0
HKD1_k127_4069377_20 - - - - 0.00005643 54.0
HKD1_k127_4069377_3 Pro-kumamolisin, activation domain K08677 - - 3.622e-227 736.0
HKD1_k127_4069377_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.341e-206 644.0
HKD1_k127_4069377_5 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 429.0
HKD1_k127_4069377_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 430.0
HKD1_k127_4069377_7 PFAM Chromosomal replication initiator, DnaA K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 379.0
HKD1_k127_4069377_8 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
HKD1_k127_4069377_9 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 336.0
HKD1_k127_4124096_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1825.0
HKD1_k127_4124096_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1324.0
HKD1_k127_4124096_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 560.0
HKD1_k127_4124096_11 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 547.0
HKD1_k127_4124096_12 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 508.0
HKD1_k127_4124096_13 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 483.0
HKD1_k127_4124096_14 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 458.0
HKD1_k127_4124096_15 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 458.0
HKD1_k127_4124096_16 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 446.0
HKD1_k127_4124096_17 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 421.0
HKD1_k127_4124096_18 lipid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 394.0
HKD1_k127_4124096_19 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
HKD1_k127_4124096_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1161.0
HKD1_k127_4124096_20 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 284.0
HKD1_k127_4124096_21 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002525 256.0
HKD1_k127_4124096_22 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000001921 214.0
HKD1_k127_4124096_23 - - - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HKD1_k127_4124096_24 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.0000000000000000000000000000000000000000000000005814 175.0
HKD1_k127_4124096_25 Sugar efflux transporter for intercellular exchange - - - 0.00000000000000000000000000000000000000000001911 165.0
HKD1_k127_4124096_27 SpoIIAA-like - - - 0.00000000000000000000000000000000000000271 150.0
HKD1_k127_4124096_28 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000002346 119.0
HKD1_k127_4124096_29 - - - - 0.00000000000000001817 90.0
HKD1_k127_4124096_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 2.756e-311 963.0
HKD1_k127_4124096_30 Transposase IS200 like - - - 0.00000000005485 70.0
HKD1_k127_4124096_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 1.604e-223 701.0
HKD1_k127_4124096_5 Phosphofructokinase K00850 - 2.7.1.11 2.38e-220 689.0
HKD1_k127_4124096_6 sulphate transporter - - - 1.144e-194 622.0
HKD1_k127_4124096_7 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 599.0
HKD1_k127_4124096_8 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 606.0
HKD1_k127_4124096_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 573.0
HKD1_k127_4153584_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit K00164 - 1.2.4.2 0.0 1446.0
HKD1_k127_4153584_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1394.0
HKD1_k127_4153584_10 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 3.232e-199 631.0
HKD1_k127_4153584_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 541.0
HKD1_k127_4153584_12 Two component signalling adaptor domain K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 511.0
HKD1_k127_4153584_13 DNA polymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 495.0
HKD1_k127_4153584_14 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 467.0
HKD1_k127_4153584_15 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 400.0
HKD1_k127_4153584_16 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 398.0
HKD1_k127_4153584_17 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 379.0
HKD1_k127_4153584_18 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
HKD1_k127_4153584_19 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 351.0
HKD1_k127_4153584_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1337.0
HKD1_k127_4153584_20 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
HKD1_k127_4153584_21 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 334.0
HKD1_k127_4153584_22 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 304.0
HKD1_k127_4153584_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 292.0
HKD1_k127_4153584_24 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 288.0
HKD1_k127_4153584_25 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 274.0
HKD1_k127_4153584_26 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 252.0
HKD1_k127_4153584_28 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007031 233.0
HKD1_k127_4153584_29 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000007256 222.0
HKD1_k127_4153584_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1104.0
HKD1_k127_4153584_30 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
HKD1_k127_4153584_31 - K07138 - - 0.000000000000000000000000000000000000000000000000002085 190.0
HKD1_k127_4153584_32 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000000000000000000001606 187.0
HKD1_k127_4153584_33 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000000008556 181.0
HKD1_k127_4153584_34 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000008333 144.0
HKD1_k127_4153584_35 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000001047 105.0
HKD1_k127_4153584_36 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000002157 64.0
HKD1_k127_4153584_4 PFAM ABC transporter related K06158 - - 0.0 1076.0
HKD1_k127_4153584_5 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0 1023.0
HKD1_k127_4153584_6 Sodium/hydrogen exchanger family K03455,K11747 - - 9.723e-317 980.0
HKD1_k127_4153584_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 2.739e-304 949.0
HKD1_k127_4153584_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 4.338e-254 796.0
HKD1_k127_4153584_9 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 2.768e-241 752.0
HKD1_k127_4173243_0 4Fe-4S dicluster domain - - - 2e-323 999.0
HKD1_k127_4173243_1 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 3.264e-300 926.0
HKD1_k127_4173243_10 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 481.0
HKD1_k127_4173243_11 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K22317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 413.0
HKD1_k127_4173243_12 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 336.0
HKD1_k127_4173243_13 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005884 251.0
HKD1_k127_4173243_14 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000007497 163.0
HKD1_k127_4173243_15 unfolded protein binding K06142 - - 0.00000000000000000000000000000000000000002793 160.0
HKD1_k127_4173243_19 Protein of unknown function (DUF2844) - - - 0.0000008284 57.0
HKD1_k127_4173243_2 electron transfer flavoprotein, alpha subunit K03522 - - 7.714e-241 748.0
HKD1_k127_4173243_3 PFAM Peptidase S10, serine carboxypeptidase - - - 1.348e-222 700.0
HKD1_k127_4173243_4 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 557.0
HKD1_k127_4173243_5 PFAM alpha beta hydrolase fold K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 541.0
HKD1_k127_4173243_6 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 529.0
HKD1_k127_4173243_7 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 499.0
HKD1_k127_4173243_8 PFAM ADP-ribosylation Crystallin J1 K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 497.0
HKD1_k127_4173243_9 SMART Elongator protein 3 MiaB NifB K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 496.0
HKD1_k127_4196401_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 2.988e-287 887.0
HKD1_k127_4196401_1 Lipoprotein - - - 7.378e-254 807.0
HKD1_k127_4196401_11 Domain of unknown function (DUF4160) - - - 0.000000000008049 69.0
HKD1_k127_4196401_12 Transposase IS200 like K07491 - - 0.00000000001184 66.0
HKD1_k127_4196401_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 527.0
HKD1_k127_4196401_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 523.0
HKD1_k127_4196401_4 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 518.0
HKD1_k127_4196401_5 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 486.0
HKD1_k127_4196401_6 - K09860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HKD1_k127_4196401_7 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005541 276.0
HKD1_k127_4196401_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HKD1_k127_4196401_9 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000777 214.0
HKD1_k127_4196408_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K11389 - 1.2.7.6 0.0 1131.0
HKD1_k127_4196408_1 Glycogen debranching enzyme - - - 2.08e-321 987.0
HKD1_k127_4196408_10 4Fe-4S dicluster domain K14091 - - 0.00000000000000000000000000000000000000000000008077 173.0
HKD1_k127_4196408_11 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000000000002844 154.0
HKD1_k127_4196408_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000003915 154.0
HKD1_k127_4196408_13 - - - - 0.00000000000000000000000000000000003473 138.0
HKD1_k127_4196408_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 3.255e-210 659.0
HKD1_k127_4196408_3 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 491.0
HKD1_k127_4196408_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 454.0
HKD1_k127_4196408_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 404.0
HKD1_k127_4196408_6 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 280.0
HKD1_k127_4196408_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000008266 222.0
HKD1_k127_4196408_8 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000000000000000000000000000005376 213.0
HKD1_k127_4196408_9 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000328 197.0
HKD1_k127_423302_0 penicillin-binding protein K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 7.54e-308 955.0
HKD1_k127_423302_1 Heat shock 70 kDa protein K04043 - - 1.746e-256 794.0
HKD1_k127_423302_2 Peptidase family M23 - - - 5.398e-199 628.0
HKD1_k127_423302_3 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 531.0
HKD1_k127_423302_5 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000005061 147.0
HKD1_k127_423302_6 Protein conserved in bacteria - - - 0.0000000000000000000001105 99.0
HKD1_k127_423302_7 Glycosyl transferase family 2 - - - 0.00001857 47.0
HKD1_k127_4259445_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0 1397.0
HKD1_k127_4259445_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0 1184.0
HKD1_k127_4259445_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 2.96e-211 660.0
HKD1_k127_4259445_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 599.0
HKD1_k127_4259445_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 599.0
HKD1_k127_4259445_13 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
HKD1_k127_4259445_14 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 548.0
HKD1_k127_4259445_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 506.0
HKD1_k127_4259445_16 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 516.0
HKD1_k127_4259445_17 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 422.0
HKD1_k127_4259445_18 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 399.0
HKD1_k127_4259445_19 EamA-like transporter family K03298 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 387.0
HKD1_k127_4259445_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1151.0
HKD1_k127_4259445_20 DNA polymerase alpha chain like domain K02347,K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 373.0
HKD1_k127_4259445_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 343.0
HKD1_k127_4259445_22 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 335.0
HKD1_k127_4259445_23 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
HKD1_k127_4259445_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
HKD1_k127_4259445_25 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 293.0
HKD1_k127_4259445_26 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 291.0
HKD1_k127_4259445_27 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 276.0
HKD1_k127_4259445_28 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005993 271.0
HKD1_k127_4259445_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001853 259.0
HKD1_k127_4259445_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1035.0
HKD1_k127_4259445_30 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002587 273.0
HKD1_k127_4259445_31 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005258 257.0
HKD1_k127_4259445_32 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
HKD1_k127_4259445_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000003595 173.0
HKD1_k127_4259445_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000285 162.0
HKD1_k127_4259445_35 ATP synthase I chain - - - 0.0000000000000000000000000000000000000000002856 162.0
HKD1_k127_4259445_36 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000002319 93.0
HKD1_k127_4259445_38 ABC-type polar amino acid transport system ATPase component - - - 0.000000000000004174 89.0
HKD1_k127_4259445_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.78e-295 908.0
HKD1_k127_4259445_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.872e-284 878.0
HKD1_k127_4259445_6 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 6.189e-269 833.0
HKD1_k127_4259445_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.74e-263 814.0
HKD1_k127_4259445_8 PFAM Aminotransferase class-III K01845 - 5.4.3.8 3.597e-253 783.0
HKD1_k127_4259445_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 9.788e-243 751.0
HKD1_k127_4287723_0 Glycosyl transferase family 2 - - - 0.0 2001.0
HKD1_k127_4287723_1 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0 1888.0
HKD1_k127_4287723_10 repeat-containing protein - - - 1.881e-228 724.0
HKD1_k127_4287723_11 Glycosyl transferase, family 2 - - - 1.947e-205 654.0
HKD1_k127_4287723_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 8.226e-205 640.0
HKD1_k127_4287723_13 transferase activity, transferring glycosyl groups K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 593.0
HKD1_k127_4287723_14 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 583.0
HKD1_k127_4287723_15 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 528.0
HKD1_k127_4287723_16 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 511.0
HKD1_k127_4287723_17 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 491.0
HKD1_k127_4287723_18 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 440.0
HKD1_k127_4287723_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 459.0
HKD1_k127_4287723_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1701.0
HKD1_k127_4287723_20 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 441.0
HKD1_k127_4287723_21 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 443.0
HKD1_k127_4287723_22 Belongs to the DegT DnrJ EryC1 family K02805,K18653 - 2.6.1.104,2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 432.0
HKD1_k127_4287723_23 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 402.0
HKD1_k127_4287723_24 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 390.0
HKD1_k127_4287723_25 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 364.0
HKD1_k127_4287723_26 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 353.0
HKD1_k127_4287723_27 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000237 305.0
HKD1_k127_4287723_28 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
HKD1_k127_4287723_29 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001251 266.0
HKD1_k127_4287723_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1675.0
HKD1_k127_4287723_30 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000007354 256.0
HKD1_k127_4287723_31 PFAM flagellar FlaF family protein K06602 - - 0.000000000000000000000000000000000000000000000000000000000000000000003081 235.0
HKD1_k127_4287723_32 Protein of unknown function (DUF563) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004744 254.0
HKD1_k127_4287723_33 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000000002418 198.0
HKD1_k127_4287723_35 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000007706 170.0
HKD1_k127_4287723_36 Adenylylsulphate kinase - - - 0.00000000000000000000000000000000001744 145.0
HKD1_k127_4287723_37 PFAM flagellar FlbT family protein K06601 - - 0.0000000000000000000000000000000001355 136.0
HKD1_k127_4287723_38 Methyltransferase domain - - - 0.000000000000000000000009169 113.0
HKD1_k127_4287723_39 - K07090 - - 0.00000000000000000001801 101.0
HKD1_k127_4287723_4 repeat-containing protein - - - 0.0 1347.0
HKD1_k127_4287723_40 Methyltransferase FkbM domain - - - 0.000000000000000003191 95.0
HKD1_k127_4287723_41 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000002292 72.0
HKD1_k127_4287723_42 Glycosyl transferases group 1 - - - 0.00004851 46.0
HKD1_k127_4287723_43 Glycosyl transferases group 1 - - - 0.0005809 42.0
HKD1_k127_4287723_5 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0 1200.0
HKD1_k127_4287723_6 Transport of potassium into the cell K03549 - - 1.925e-319 985.0
HKD1_k127_4287723_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.556e-287 886.0
HKD1_k127_4287723_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.687e-271 840.0
HKD1_k127_4287723_9 glycosyl transferase - - - 4.643e-263 829.0
HKD1_k127_4355934_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1172.0
HKD1_k127_4355934_1 ATP-binding region ATPase domain protein - - - 0.0 1152.0
HKD1_k127_4355934_10 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000005964 129.0
HKD1_k127_4355934_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 1.845e-256 795.0
HKD1_k127_4355934_3 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 471.0
HKD1_k127_4355934_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 391.0
HKD1_k127_4355934_5 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 335.0
HKD1_k127_4355934_6 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008931 274.0
HKD1_k127_4355934_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000000000000000000000000002715 207.0
HKD1_k127_4355934_8 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.0000000000000000000000000000000000002035 143.0
HKD1_k127_4355934_9 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000002326 139.0
HKD1_k127_4374068_0 AcrB/AcrD/AcrF family K03296 - - 0.0 2430.0
HKD1_k127_4374068_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1630.0
HKD1_k127_4374068_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1148.0
HKD1_k127_4374068_100 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006658 239.0
HKD1_k127_4374068_101 TIGRFAM general secretion pathway protein F K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000004199 243.0
HKD1_k127_4374068_102 phosphorelay signal transduction system K03974 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
HKD1_k127_4374068_103 Protein of unknown function (DUF327) K09770 - - 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
HKD1_k127_4374068_104 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000000000000000000000000000000000000000000000005991 224.0
HKD1_k127_4374068_105 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
HKD1_k127_4374068_106 chemotaxis K03410 - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HKD1_k127_4374068_107 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000005038 220.0
HKD1_k127_4374068_109 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000002359 201.0
HKD1_k127_4374068_11 PFAM Type II secretion system protein E K02454 - - 9.279e-313 961.0
HKD1_k127_4374068_110 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
HKD1_k127_4374068_111 - - - - 0.000000000000000000000000000000000000000000000000000007945 195.0
HKD1_k127_4374068_112 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000007972 192.0
HKD1_k127_4374068_113 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000001343 188.0
HKD1_k127_4374068_114 PFAM Methylamine - - - 0.000000000000000000000000000000000000000000000000003863 186.0
HKD1_k127_4374068_115 gas vesicle protein - - - 0.0000000000000000000000000000000000000000000000005494 176.0
HKD1_k127_4374068_116 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000004435 177.0
HKD1_k127_4374068_117 Bacterial protein of unknown function (DUF948) - - - 0.0000000000000000000000000000000000000000000003295 169.0
HKD1_k127_4374068_12 Belongs to the thiolase family K00626 - 2.3.1.9 1.086e-307 948.0
HKD1_k127_4374068_123 chemotaxis K03408,K03415 - - 0.000000000000000000000000000000001757 136.0
HKD1_k127_4374068_124 metal cluster binding K06940 - - 0.000000000000000000000000000000002706 133.0
HKD1_k127_4374068_126 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000009864 124.0
HKD1_k127_4374068_127 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000001433 122.0
HKD1_k127_4374068_128 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000000000003528 119.0
HKD1_k127_4374068_129 YHS domain - - - 0.0000000000000000000000000000461 117.0
HKD1_k127_4374068_13 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 1.723e-305 949.0
HKD1_k127_4374068_130 - - - - 0.00000000000000000001541 93.0
HKD1_k127_4374068_132 regulation of response to stimulus K02014,K13730 - - 0.00000000000000005563 95.0
HKD1_k127_4374068_133 Chagasin family peptidase inhibitor I42 - - - 0.000000000000008255 85.0
HKD1_k127_4374068_139 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.000000000821 62.0
HKD1_k127_4374068_14 Type II and III secretion system protein K02453 - - 3.749e-303 940.0
HKD1_k127_4374068_141 - - - - 0.000001259 60.0
HKD1_k127_4374068_142 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000001342 61.0
HKD1_k127_4374068_143 hydrolase family 81 - - - 0.0001492 55.0
HKD1_k127_4374068_144 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0003668 51.0
HKD1_k127_4374068_15 TIGRFAM YidE YbjL duplication K07085 - - 7.223e-298 925.0
HKD1_k127_4374068_16 Protein of unknown function (DUF3373) - - - 1.525e-291 902.0
HKD1_k127_4374068_17 Tetratricopeptide TPR_2 repeat protein - - - 1.558e-291 911.0
HKD1_k127_4374068_18 SMART PAS domain containing protein - - - 5.132e-289 904.0
HKD1_k127_4374068_19 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 5.376e-287 886.0
HKD1_k127_4374068_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1433.0
HKD1_k127_4374068_20 DHHA2 domain protein K15986 - 3.6.1.1 4.537e-283 877.0
HKD1_k127_4374068_21 PFAM carboxyl transferase - - - 2.406e-278 857.0
HKD1_k127_4374068_22 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 3.24e-275 849.0
HKD1_k127_4374068_23 Cytochrome c554 and c-prime - - - 1.182e-274 852.0
HKD1_k127_4374068_24 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.72e-266 822.0
HKD1_k127_4374068_25 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 6.146e-264 824.0
HKD1_k127_4374068_26 response regulator - - - 1.593e-263 818.0
HKD1_k127_4374068_27 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.145e-261 808.0
HKD1_k127_4374068_28 PFAM aminotransferase, class I and II K00814 - 2.6.1.2 2.569e-260 805.0
HKD1_k127_4374068_29 phosphorelay signal transduction system - - - 5.167e-257 809.0
HKD1_k127_4374068_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1322.0
HKD1_k127_4374068_30 4Fe-4S dicluster domain K11473 - - 2.799e-253 785.0
HKD1_k127_4374068_31 histidine kinase, HAMP K02482 - 2.7.13.3 1.404e-250 784.0
HKD1_k127_4374068_32 two component, sigma54 specific, transcriptional regulator K02481 - - 4.307e-240 748.0
HKD1_k127_4374068_33 UvrD-like helicase C-terminal domain - - - 4.218e-238 752.0
HKD1_k127_4374068_34 Domain of unknown function (DUF2088) - - - 4.227e-224 699.0
HKD1_k127_4374068_35 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 3.044e-217 687.0
HKD1_k127_4374068_36 PFAM penicillin-binding protein transpeptidase - - - 8.829e-216 676.0
HKD1_k127_4374068_37 TIGRFAM branched-chain amino acid aminotransferase K00826 - 2.6.1.42 1.116e-208 652.0
HKD1_k127_4374068_38 transmembrane signaling receptor activity K03406 - - 2.14e-204 643.0
HKD1_k127_4374068_39 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 8.873e-198 616.0
HKD1_k127_4374068_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0 1240.0
HKD1_k127_4374068_40 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 603.0
HKD1_k127_4374068_41 PFAM ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 591.0
HKD1_k127_4374068_42 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 578.0
HKD1_k127_4374068_43 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 570.0
HKD1_k127_4374068_45 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 565.0
HKD1_k127_4374068_46 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 559.0
HKD1_k127_4374068_47 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 552.0
HKD1_k127_4374068_48 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 550.0
HKD1_k127_4374068_49 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 524.0
HKD1_k127_4374068_5 PFAM alpha amylase catalytic region - - - 0.0 1213.0
HKD1_k127_4374068_50 12 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 522.0
HKD1_k127_4374068_51 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 505.0
HKD1_k127_4374068_52 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 503.0
HKD1_k127_4374068_53 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 497.0
HKD1_k127_4374068_54 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 491.0
HKD1_k127_4374068_55 Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 493.0
HKD1_k127_4374068_56 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 484.0
HKD1_k127_4374068_57 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 481.0
HKD1_k127_4374068_58 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 474.0
HKD1_k127_4374068_59 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 467.0
HKD1_k127_4374068_6 histidine kinase HAMP region domain protein K03406 - - 0.0 1209.0
HKD1_k127_4374068_60 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 466.0
HKD1_k127_4374068_61 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 443.0
HKD1_k127_4374068_62 SMART PDZ DHR GLGF domain protein K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 441.0
HKD1_k127_4374068_63 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 446.0
HKD1_k127_4374068_64 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 429.0
HKD1_k127_4374068_65 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 416.0
HKD1_k127_4374068_66 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 419.0
HKD1_k127_4374068_67 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 410.0
HKD1_k127_4374068_68 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 411.0
HKD1_k127_4374068_69 Histidine kinase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 404.0
HKD1_k127_4374068_7 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0 1205.0
HKD1_k127_4374068_70 Pfam:UPF0118 K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 401.0
HKD1_k127_4374068_71 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 408.0
HKD1_k127_4374068_72 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 393.0
HKD1_k127_4374068_73 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 383.0
HKD1_k127_4374068_74 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 381.0
HKD1_k127_4374068_75 cysteine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 375.0
HKD1_k127_4374068_76 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 368.0
HKD1_k127_4374068_77 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 358.0
HKD1_k127_4374068_78 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 359.0
HKD1_k127_4374068_79 Chemotaxis K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 377.0
HKD1_k127_4374068_8 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1198.0
HKD1_k127_4374068_80 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 359.0
HKD1_k127_4374068_81 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
HKD1_k127_4374068_82 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 337.0
HKD1_k127_4374068_83 Peptidase S24-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 322.0
HKD1_k127_4374068_84 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
HKD1_k127_4374068_85 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 303.0
HKD1_k127_4374068_86 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 300.0
HKD1_k127_4374068_87 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 291.0
HKD1_k127_4374068_88 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
HKD1_k127_4374068_89 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002584 278.0
HKD1_k127_4374068_9 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1149.0
HKD1_k127_4374068_90 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001485 278.0
HKD1_k127_4374068_91 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HKD1_k127_4374068_93 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000869 262.0
HKD1_k127_4374068_94 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
HKD1_k127_4374068_96 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
HKD1_k127_4374068_97 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009414 248.0
HKD1_k127_4374068_98 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003623 247.0
HKD1_k127_4374068_99 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003495 239.0
HKD1_k127_4473766_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1552.0
HKD1_k127_4473766_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0 1533.0
HKD1_k127_4473766_10 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 3.343e-213 668.0
HKD1_k127_4473766_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 525.0
HKD1_k127_4473766_12 PFAM ROK family protein K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 488.0
HKD1_k127_4473766_13 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 484.0
HKD1_k127_4473766_14 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 475.0
HKD1_k127_4473766_15 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 470.0
HKD1_k127_4473766_16 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 465.0
HKD1_k127_4473766_17 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 454.0
HKD1_k127_4473766_18 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 442.0
HKD1_k127_4473766_19 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 409.0
HKD1_k127_4473766_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1489.0
HKD1_k127_4473766_20 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 404.0
HKD1_k127_4473766_21 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 305.0
HKD1_k127_4473766_22 Smr protein MutS2 - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 292.0
HKD1_k127_4473766_23 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000708 282.0
HKD1_k127_4473766_24 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002701 278.0
HKD1_k127_4473766_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 258.0
HKD1_k127_4473766_26 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005738 244.0
HKD1_k127_4473766_27 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
HKD1_k127_4473766_28 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
HKD1_k127_4473766_29 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000001746 181.0
HKD1_k127_4473766_3 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1061.0
HKD1_k127_4473766_30 CoA carboxylase activity K01965,K17490 - 2.1.3.1,6.4.1.3 0.000000000000000000000000000000000000000000000006489 174.0
HKD1_k127_4473766_31 - - - - 0.00000000000000000000000000000000001544 136.0
HKD1_k127_4473766_32 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.0000000000000000000000000000000000581 133.0
HKD1_k127_4473766_33 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000001731 130.0
HKD1_k127_4473766_34 PilZ domain - - - 0.00000000000000000000000000004811 129.0
HKD1_k127_4473766_37 - - - - 0.000000000000000000000005497 101.0
HKD1_k127_4473766_38 - - - - 0.000000000000000000006638 92.0
HKD1_k127_4473766_39 - - - - 0.0000000000000000000758 90.0
HKD1_k127_4473766_4 Pyruvate carboxyltransferase K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 1.868e-290 896.0
HKD1_k127_4473766_40 PFAM glycosyl transferase group 1 - - - 0.00000000001398 65.0
HKD1_k127_4473766_41 - - - - 0.0000000005472 72.0
HKD1_k127_4473766_42 domain protein K02238 - - 0.0001309 54.0
HKD1_k127_4473766_5 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 2.241e-290 896.0
HKD1_k127_4473766_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 7.145e-275 857.0
HKD1_k127_4473766_7 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 1.02e-239 752.0
HKD1_k127_4473766_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 6.361e-226 703.0
HKD1_k127_4473766_9 RmuC family K09760 - - 1.776e-223 703.0
HKD1_k127_4485572_0 Collagenase K08303 - - 0.0 1324.0
HKD1_k127_4485572_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0 1159.0
HKD1_k127_4485572_10 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 550.0
HKD1_k127_4485572_11 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 527.0
HKD1_k127_4485572_12 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 504.0
HKD1_k127_4485572_13 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 480.0
HKD1_k127_4485572_14 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 468.0
HKD1_k127_4485572_15 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 463.0
HKD1_k127_4485572_16 PFAM ABC transporter related K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 452.0
HKD1_k127_4485572_17 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 450.0
HKD1_k127_4485572_18 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 436.0
HKD1_k127_4485572_19 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 421.0
HKD1_k127_4485572_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 2.083e-250 777.0
HKD1_k127_4485572_20 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 419.0
HKD1_k127_4485572_21 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 402.0
HKD1_k127_4485572_22 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 403.0
HKD1_k127_4485572_23 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 392.0
HKD1_k127_4485572_24 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 388.0
HKD1_k127_4485572_25 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 355.0
HKD1_k127_4485572_26 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 337.0
HKD1_k127_4485572_27 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 341.0
HKD1_k127_4485572_28 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
HKD1_k127_4485572_29 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
HKD1_k127_4485572_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K00595 - 2.1.1.132 1.383e-249 775.0
HKD1_k127_4485572_31 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 299.0
HKD1_k127_4485572_32 belongs to the Fur family K02076,K03711,K09823 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005178 262.0
HKD1_k127_4485572_33 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001598 261.0
HKD1_k127_4485572_34 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005422 268.0
HKD1_k127_4485572_36 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
HKD1_k127_4485572_37 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000005143 239.0
HKD1_k127_4485572_38 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000000000000000008319 235.0
HKD1_k127_4485572_39 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD1_k127_4485572_4 PFAM peptidase M16 domain protein K07263 - - 7.758e-231 720.0
HKD1_k127_4485572_40 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HKD1_k127_4485572_44 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000000000000003352 106.0
HKD1_k127_4485572_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 2.816e-204 641.0
HKD1_k127_4485572_6 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 2.199e-197 619.0
HKD1_k127_4485572_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 3.72e-196 621.0
HKD1_k127_4485572_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 567.0
HKD1_k127_4485572_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 567.0
HKD1_k127_4487383_0 AsmA-like C-terminal region - - - 0.0 1308.0
HKD1_k127_4487383_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.0 1244.0
HKD1_k127_4487383_10 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 8.776e-264 816.0
HKD1_k127_4487383_11 SMART Elongator protein 3 MiaB NifB - - - 2.118e-263 821.0
HKD1_k127_4487383_12 AMP-binding enzyme K01897 - 6.2.1.3 5.202e-242 763.0
HKD1_k127_4487383_13 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 7.132e-223 692.0
HKD1_k127_4487383_14 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 9.373e-222 689.0
HKD1_k127_4487383_15 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 2.807e-216 680.0
HKD1_k127_4487383_16 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 8.677e-203 633.0
HKD1_k127_4487383_17 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.615e-202 632.0
HKD1_k127_4487383_18 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 2.647e-197 652.0
HKD1_k127_4487383_19 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 583.0
HKD1_k127_4487383_2 thiolester hydrolase activity - - - 0.0 1086.0
HKD1_k127_4487383_20 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 557.0
HKD1_k127_4487383_21 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 546.0
HKD1_k127_4487383_22 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 517.0
HKD1_k127_4487383_23 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 518.0
HKD1_k127_4487383_24 Domains LysM, LysM, NLPC_P60 K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 508.0
HKD1_k127_4487383_25 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 505.0
HKD1_k127_4487383_26 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 438.0
HKD1_k127_4487383_27 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 410.0
HKD1_k127_4487383_28 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 369.0
HKD1_k127_4487383_29 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 366.0
HKD1_k127_4487383_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0 1070.0
HKD1_k127_4487383_30 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 351.0
HKD1_k127_4487383_31 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 287.0
HKD1_k127_4487383_32 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007026 278.0
HKD1_k127_4487383_33 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009213 269.0
HKD1_k127_4487383_34 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000007933 266.0
HKD1_k127_4487383_35 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009573 252.0
HKD1_k127_4487383_36 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 246.0
HKD1_k127_4487383_37 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 238.0
HKD1_k127_4487383_38 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000001539 207.0
HKD1_k127_4487383_39 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000007707 202.0
HKD1_k127_4487383_4 General secretory system II, protein E domain protein K02454 - - 0.0 1054.0
HKD1_k127_4487383_40 CDP-diacylglycerol pyrophosphatase K01521 - 3.6.1.26 0.00000000000000000000000000000000000000000000000000006534 197.0
HKD1_k127_4487383_41 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000002702 200.0
HKD1_k127_4487383_42 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000002152 149.0
HKD1_k127_4487383_43 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000002701 143.0
HKD1_k127_4487383_44 - - - - 0.00000000000000000000000000000001592 132.0
HKD1_k127_4487383_46 - - - - 0.00000000000000000000001273 103.0
HKD1_k127_4487383_47 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - 0.00000000000000004614 84.0
HKD1_k127_4487383_5 SMART Elongator protein 3 MiaB NifB - - - 0.0 1038.0
HKD1_k127_4487383_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 2.006e-305 943.0
HKD1_k127_4487383_7 Response regulator, receiver - - - 5.643e-293 916.0
HKD1_k127_4487383_8 ABC1 family K03688 - - 6.489e-284 884.0
HKD1_k127_4487383_9 SMART Elongator protein 3 MiaB NifB - - - 1.293e-277 856.0
HKD1_k127_4487404_0 Eco57I restriction-modification methylase - - - 5.492e-289 895.0
HKD1_k127_4487404_1 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 504.0
HKD1_k127_4487404_10 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
HKD1_k127_4487404_11 Transposase IS200 like K07491 - - 0.0000000000000000000000000000004129 128.0
HKD1_k127_4487404_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 460.0
HKD1_k127_4487404_3 Restriction endonuclease XhoI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 441.0
HKD1_k127_4487404_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 355.0
HKD1_k127_4487404_5 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 281.0
HKD1_k127_4487404_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 279.0
HKD1_k127_4487404_7 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002123 274.0
HKD1_k127_4487404_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
HKD1_k127_4487404_9 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
HKD1_k127_4533477_0 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0 3533.0
HKD1_k127_4533477_1 PFAM Beta-ketoacyl synthase - - - 0.0 3521.0
HKD1_k127_4533477_10 Histidine kinase - - - 0.0 1050.0
HKD1_k127_4533477_100 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000000000000000000001492 155.0
HKD1_k127_4533477_101 cell redox homeostasis - - - 0.0000000000000000000000000000000000000003467 157.0
HKD1_k127_4533477_102 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000000000000001152 151.0
HKD1_k127_4533477_103 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000004677 159.0
HKD1_k127_4533477_104 GYD domain - - - 0.00000000000000000000000000000000002466 137.0
HKD1_k127_4533477_107 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000000000000000000004484 129.0
HKD1_k127_4533477_108 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000001299 144.0
HKD1_k127_4533477_109 membrane - - - 0.0000000000000000000000000003637 117.0
HKD1_k127_4533477_11 Histidine kinase - - - 0.0 1045.0
HKD1_k127_4533477_110 - - - - 0.0000000000000000000000002071 108.0
HKD1_k127_4533477_111 Rubredoxin - - - 0.0000000000000000000000007398 104.0
HKD1_k127_4533477_112 - - - - 0.0000000000000000000000007537 104.0
HKD1_k127_4533477_113 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000001855 107.0
HKD1_k127_4533477_115 Rubrerythrin - - - 0.0000000000000000000003958 96.0
HKD1_k127_4533477_116 - - - - 0.00000000000000000001018 96.0
HKD1_k127_4533477_117 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000002875 86.0
HKD1_k127_4533477_118 organic phosphonate transport K02044 - - 0.00000000000000003682 89.0
HKD1_k127_4533477_119 PFAM SpoVT AbrB K07172,K18842 - - 0.000000000000000151 82.0
HKD1_k127_4533477_12 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0 1026.0
HKD1_k127_4533477_120 - - - - 0.0000000003406 62.0
HKD1_k127_4533477_121 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.0000001432 56.0
HKD1_k127_4533477_125 LacY proton/sugar symporter - - - 0.0002896 45.0
HKD1_k127_4533477_13 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.187e-308 953.0
HKD1_k127_4533477_14 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.404e-304 940.0
HKD1_k127_4533477_15 type IV pilus assembly PilZ - - - 4.688e-295 920.0
HKD1_k127_4533477_16 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 3.117e-277 860.0
HKD1_k127_4533477_17 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.6e-273 842.0
HKD1_k127_4533477_18 Histidine kinase K02482 - 2.7.13.3 6.619e-271 871.0
HKD1_k127_4533477_19 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.153e-269 829.0
HKD1_k127_4533477_2 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2173.0
HKD1_k127_4533477_20 Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing - - - 7.297e-266 840.0
HKD1_k127_4533477_21 photoreceptor activity - - - 1.822e-247 775.0
HKD1_k127_4533477_22 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 8.135e-241 751.0
HKD1_k127_4533477_23 TIGRFAM PfaD family protein - - - 5.473e-232 730.0
HKD1_k127_4533477_24 Aldehyde dehydrogenase family K22187 - - 2.335e-217 684.0
HKD1_k127_4533477_25 MacB-like periplasmic core domain K02004 - - 6.454e-216 676.0
HKD1_k127_4533477_26 PFAM Major Facilitator Superfamily - - - 7.424e-212 665.0
HKD1_k127_4533477_27 PFAM Extracellular ligand-binding receptor K01999 - - 1.003e-211 661.0
HKD1_k127_4533477_28 PFAM Extracellular ligand-binding receptor K01999 - - 1.188e-208 654.0
HKD1_k127_4533477_29 Belongs to the thiolase family K00632 - 2.3.1.16 2.866e-201 632.0
HKD1_k127_4533477_3 Histidine kinase A domain protein - - - 0.0 1587.0
HKD1_k127_4533477_30 PFAM outer membrane efflux protein - - - 1.59e-196 636.0
HKD1_k127_4533477_31 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 580.0
HKD1_k127_4533477_32 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 587.0
HKD1_k127_4533477_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 579.0
HKD1_k127_4533477_34 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 576.0
HKD1_k127_4533477_35 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 573.0
HKD1_k127_4533477_36 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 531.0
HKD1_k127_4533477_37 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 528.0
HKD1_k127_4533477_38 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 511.0
HKD1_k127_4533477_39 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 509.0
HKD1_k127_4533477_4 GGDEF domain containing protein - - - 0.0 1287.0
HKD1_k127_4533477_40 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 507.0
HKD1_k127_4533477_41 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 497.0
HKD1_k127_4533477_42 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 506.0
HKD1_k127_4533477_43 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 494.0
HKD1_k127_4533477_44 Sensory domain found in PocR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 501.0
HKD1_k127_4533477_45 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 484.0
HKD1_k127_4533477_46 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 464.0
HKD1_k127_4533477_47 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 444.0
HKD1_k127_4533477_48 PFAM Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 443.0
HKD1_k127_4533477_49 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 445.0
HKD1_k127_4533477_5 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1278.0
HKD1_k127_4533477_50 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 430.0
HKD1_k127_4533477_51 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 427.0
HKD1_k127_4533477_52 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 413.0
HKD1_k127_4533477_53 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 413.0
HKD1_k127_4533477_54 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 394.0
HKD1_k127_4533477_55 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 383.0
HKD1_k127_4533477_56 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 378.0
HKD1_k127_4533477_57 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 374.0
HKD1_k127_4533477_58 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 359.0
HKD1_k127_4533477_59 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 353.0
HKD1_k127_4533477_6 Histidine kinase K02482 - 2.7.13.3 0.0 1173.0
HKD1_k127_4533477_60 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 345.0
HKD1_k127_4533477_61 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 355.0
HKD1_k127_4533477_62 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 348.0
HKD1_k127_4533477_63 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 332.0
HKD1_k127_4533477_64 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
HKD1_k127_4533477_65 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 347.0
HKD1_k127_4533477_66 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 327.0
HKD1_k127_4533477_67 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 317.0
HKD1_k127_4533477_68 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 310.0
HKD1_k127_4533477_69 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 315.0
HKD1_k127_4533477_7 FtsX-like permease family K02004 - - 0.0 1154.0
HKD1_k127_4533477_70 fatty acid responsive transcription factor FadR domain protein K03603 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
HKD1_k127_4533477_71 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 317.0
HKD1_k127_4533477_72 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 304.0
HKD1_k127_4533477_73 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 303.0
HKD1_k127_4533477_74 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 287.0
HKD1_k127_4533477_75 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002574 282.0
HKD1_k127_4533477_76 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
HKD1_k127_4533477_77 Acyl carrier protein phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 275.0
HKD1_k127_4533477_78 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HKD1_k127_4533477_79 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001016 267.0
HKD1_k127_4533477_8 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1142.0
HKD1_k127_4533477_80 Serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002104 262.0
HKD1_k127_4533477_82 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
HKD1_k127_4533477_83 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008403 228.0
HKD1_k127_4533477_84 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000001562 231.0
HKD1_k127_4533477_85 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000003669 222.0
HKD1_k127_4533477_86 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000007452 229.0
HKD1_k127_4533477_87 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000005269 206.0
HKD1_k127_4533477_88 PFAM NosL family protein - - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HKD1_k127_4533477_89 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD1_k127_4533477_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1075.0
HKD1_k127_4533477_90 - - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
HKD1_k127_4533477_91 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000000000000000000008167 193.0
HKD1_k127_4533477_92 NosL - - - 0.000000000000000000000000000000000000000000000000000004547 197.0
HKD1_k127_4533477_93 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000000000000001877 191.0
HKD1_k127_4533477_94 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000000001238 181.0
HKD1_k127_4533477_95 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000002376 168.0
HKD1_k127_4533477_96 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000008879 166.0
HKD1_k127_4533477_97 Protein of unknown function DUF134 - - - 0.00000000000000000000000000000000000000000000929 168.0
HKD1_k127_4533477_98 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000006166 163.0
HKD1_k127_4533477_99 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000002283 161.0
HKD1_k127_4597241_0 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 542.0
HKD1_k127_4597241_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 408.0
HKD1_k127_4597241_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
HKD1_k127_4597241_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
HKD1_k127_4597241_4 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.000000000000000000000000000000000000000000000000000368 188.0
HKD1_k127_4597241_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000003934 148.0
HKD1_k127_4597241_6 Domain of unknown function (DUF1904) - - - 0.0000000000000000000000000000584 119.0
HKD1_k127_4597241_7 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.00000000000000000000000006876 108.0
HKD1_k127_4664568_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0 1063.0
HKD1_k127_4664568_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1032.0
HKD1_k127_4664568_10 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002027 270.0
HKD1_k127_4664568_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005074 263.0
HKD1_k127_4664568_12 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
HKD1_k127_4664568_13 Deoxyinosine 3'endonuclease (endonuclease V) K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000003788 189.0
HKD1_k127_4664568_14 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000008379 168.0
HKD1_k127_4664568_15 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000001035 128.0
HKD1_k127_4664568_16 protein secretion K03116 - - 0.0000000000000000000002098 97.0
HKD1_k127_4664568_2 PFAM Polysulphide reductase, NrfD - - - 4.854e-249 773.0
HKD1_k127_4664568_3 Histidine kinase HAMP K02482 - 2.7.13.3 7.568e-245 774.0
HKD1_k127_4664568_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 4.337e-224 703.0
HKD1_k127_4664568_5 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 1.175e-220 687.0
HKD1_k127_4664568_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 604.0
HKD1_k127_4664568_7 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 514.0
HKD1_k127_4664568_8 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 409.0
HKD1_k127_4664568_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 291.0
HKD1_k127_48457_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.657e-304 941.0
HKD1_k127_48457_1 histidine kinase HAMP region domain protein K03406 - - 4.003e-295 922.0
HKD1_k127_48457_10 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002403 258.0
HKD1_k127_48457_11 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001684 239.0
HKD1_k127_48457_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000009253 226.0
HKD1_k127_48457_13 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000005244 216.0
HKD1_k127_48457_15 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000006697 115.0
HKD1_k127_48457_2 TIGRFAM YidE YbjL duplication K07085 - - 4.205e-281 873.0
HKD1_k127_48457_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.606e-223 696.0
HKD1_k127_48457_4 Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 468.0
HKD1_k127_48457_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 455.0
HKD1_k127_48457_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 446.0
HKD1_k127_48457_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 354.0
HKD1_k127_48457_8 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 369.0
HKD1_k127_48457_9 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 288.0
HKD1_k127_5100632_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0 1560.0
HKD1_k127_5100632_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1062.0
HKD1_k127_5100632_10 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 511.0
HKD1_k127_5100632_11 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
HKD1_k127_5100632_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 458.0
HKD1_k127_5100632_13 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 451.0
HKD1_k127_5100632_14 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 431.0
HKD1_k127_5100632_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 412.0
HKD1_k127_5100632_16 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 407.0
HKD1_k127_5100632_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 368.0
HKD1_k127_5100632_19 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009625 256.0
HKD1_k127_5100632_2 Histidine kinase - - - 2.774e-307 946.0
HKD1_k127_5100632_20 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
HKD1_k127_5100632_21 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000001409 213.0
HKD1_k127_5100632_25 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000003023 75.0
HKD1_k127_5100632_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 5.015e-292 899.0
HKD1_k127_5100632_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.979e-272 846.0
HKD1_k127_5100632_5 response regulator K02481,K07715 - - 1.691e-256 795.0
HKD1_k127_5100632_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 1.397e-254 791.0
HKD1_k127_5100632_7 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 570.0
HKD1_k127_5100632_8 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 562.0
HKD1_k127_5100632_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 543.0
HKD1_k127_5188169_0 Histidine kinase K07646 - 2.7.13.3 0.0 1386.0
HKD1_k127_5188169_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1303.0
HKD1_k127_5188169_10 PFAM chemotaxis sensory transducer K03406 - - 7.815e-232 728.0
HKD1_k127_5188169_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 2.895e-217 679.0
HKD1_k127_5188169_12 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 1.743e-209 653.0
HKD1_k127_5188169_13 PFAM aminotransferase class I and II K14155 - 4.4.1.8 1.145e-204 642.0
HKD1_k127_5188169_14 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 603.0
HKD1_k127_5188169_15 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 599.0
HKD1_k127_5188169_16 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 587.0
HKD1_k127_5188169_17 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 591.0
HKD1_k127_5188169_18 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 547.0
HKD1_k127_5188169_19 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 536.0
HKD1_k127_5188169_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1225.0
HKD1_k127_5188169_20 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 540.0
HKD1_k127_5188169_21 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
HKD1_k127_5188169_22 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 520.0
HKD1_k127_5188169_23 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 512.0
HKD1_k127_5188169_24 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 464.0
HKD1_k127_5188169_25 PFAM flagellin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 438.0
HKD1_k127_5188169_26 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 423.0
HKD1_k127_5188169_27 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
HKD1_k127_5188169_28 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
HKD1_k127_5188169_29 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 350.0
HKD1_k127_5188169_3 Elongation factor SelB winged helix 3 K03833 - - 0.0 1133.0
HKD1_k127_5188169_30 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 332.0
HKD1_k127_5188169_31 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD1_k127_5188169_32 Papain cysteine protease family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
HKD1_k127_5188169_33 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 296.0
HKD1_k127_5188169_34 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003558 276.0
HKD1_k127_5188169_35 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 245.0
HKD1_k127_5188169_36 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HKD1_k127_5188169_37 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000005121 211.0
HKD1_k127_5188169_38 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000002672 196.0
HKD1_k127_5188169_4 amino acid - - - 0.0 1107.0
HKD1_k127_5188169_40 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000000000000000000002596 153.0
HKD1_k127_5188169_41 DNA methylase K07316 - 2.1.1.72 0.00000000000000000000000000000000006799 145.0
HKD1_k127_5188169_42 DNA methylase K07316 - 2.1.1.72 0.000000000000000000000000000000000276 139.0
HKD1_k127_5188169_43 Transcriptional regulator - - - 0.00000000000000000000000000000001085 129.0
HKD1_k127_5188169_46 Protein of unknown function (DUF2845) - - - 0.00000000000000001999 93.0
HKD1_k127_5188169_47 - - - - 0.000000000000001482 84.0
HKD1_k127_5188169_49 metallopeptidase activity - - - 0.00004016 55.0
HKD1_k127_5188169_5 - - - - 0.0 1103.0
HKD1_k127_5188169_50 - - - - 0.00005571 47.0
HKD1_k127_5188169_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 3.9e-322 993.0
HKD1_k127_5188169_7 ABC transporter transmembrane region K06147,K18890 - - 2.34e-316 975.0
HKD1_k127_5188169_8 ABC transporter transmembrane region K06147,K18889 - - 2.107e-288 894.0
HKD1_k127_5188169_9 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.042e-253 784.0
HKD1_k127_5262251_0 Polysaccharide biosynthesis protein CapD - - - 0.0 1039.0
HKD1_k127_5262251_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0 1035.0
HKD1_k127_5262251_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 607.0
HKD1_k127_5262251_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 600.0
HKD1_k127_5262251_12 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 579.0
HKD1_k127_5262251_13 NAD(P)H-binding K15894 - 4.2.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 559.0
HKD1_k127_5262251_14 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 492.0
HKD1_k127_5262251_15 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 488.0
HKD1_k127_5262251_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 472.0
HKD1_k127_5262251_17 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 465.0
HKD1_k127_5262251_18 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 437.0
HKD1_k127_5262251_19 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 421.0
HKD1_k127_5262251_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 4.985e-308 960.0
HKD1_k127_5262251_20 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 398.0
HKD1_k127_5262251_21 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 398.0
HKD1_k127_5262251_22 Histidine kinase K20971,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 372.0
HKD1_k127_5262251_23 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 368.0
HKD1_k127_5262251_24 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 343.0
HKD1_k127_5262251_26 Catalyzes the synthesis of activated sulfate K00860,K00955,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 328.0
HKD1_k127_5262251_27 PFAM lipopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 316.0
HKD1_k127_5262251_28 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 312.0
HKD1_k127_5262251_29 Bacterial sugar transferase K13012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
HKD1_k127_5262251_3 Catalase K03781 - 1.11.1.6 3.287e-278 863.0
HKD1_k127_5262251_30 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 318.0
HKD1_k127_5262251_31 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 311.0
HKD1_k127_5262251_32 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007851 281.0
HKD1_k127_5262251_33 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 273.0
HKD1_k127_5262251_34 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000168 264.0
HKD1_k127_5262251_35 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HKD1_k127_5262251_36 Glycosyl transferase, family 2 K07011,K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000001827 254.0
HKD1_k127_5262251_37 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000000000000000000000000000000000000000001641 219.0
HKD1_k127_5262251_38 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000000000000000000000000000000000000003401 204.0
HKD1_k127_5262251_39 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000004398 190.0
HKD1_k127_5262251_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 3.634e-276 863.0
HKD1_k127_5262251_40 methyltransferase activity K00563,K02169 - 2.1.1.187,2.1.1.197 0.00000000000000000000000000000000000000000000001166 179.0
HKD1_k127_5262251_41 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000001684 168.0
HKD1_k127_5262251_42 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000000000000001067 158.0
HKD1_k127_5262251_44 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000001683 137.0
HKD1_k127_5262251_45 belongs to the thioredoxin family - - - 0.00000000000000000000000000007471 132.0
HKD1_k127_5262251_46 cheY-homologous receiver domain - - - 0.0000000000000000000000004953 108.0
HKD1_k127_5262251_48 Glycosyl transferase, family 2 - - - 0.0000000001215 73.0
HKD1_k127_5262251_5 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 7.014e-264 826.0
HKD1_k127_5262251_6 Capsule assembly protein Wzi - - - 5.283e-256 799.0
HKD1_k127_5262251_7 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 1.912e-213 671.0
HKD1_k127_5262251_8 Asparagine synthase K01953 - 6.3.5.4 3.689e-212 677.0
HKD1_k127_5262251_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 607.0
HKD1_k127_5324510_0 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 5.254e-299 921.0
HKD1_k127_5324510_1 Domain of unknown function (DUF4445) - - - 2.909e-246 771.0
HKD1_k127_5324510_10 SMART Elongator protein 3 MiaB NifB K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 421.0
HKD1_k127_5324510_11 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 380.0
HKD1_k127_5324510_12 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 382.0
HKD1_k127_5324510_13 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 339.0
HKD1_k127_5324510_14 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 323.0
HKD1_k127_5324510_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 295.0
HKD1_k127_5324510_16 Domain of unknown function (DUF4384) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 291.0
HKD1_k127_5324510_17 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005422 257.0
HKD1_k127_5324510_18 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 266.0
HKD1_k127_5324510_19 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000002008 210.0
HKD1_k127_5324510_2 Beta-eliminating lyase K04487 - 2.8.1.7 1.119e-195 619.0
HKD1_k127_5324510_20 Ferredoxin - - - 0.0000000000000000000000000000000000000000009035 162.0
HKD1_k127_5324510_21 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000002984 148.0
HKD1_k127_5324510_22 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000003801 135.0
HKD1_k127_5324510_23 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000001726 137.0
HKD1_k127_5324510_28 pyridoxamine 5-phosphate - - - 0.00000000003363 68.0
HKD1_k127_5324510_3 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 600.0
HKD1_k127_5324510_4 COG2710 Nitrogenase molybdenum-iron protein alpha and beta K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 581.0
HKD1_k127_5324510_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 571.0
HKD1_k127_5324510_6 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 541.0
HKD1_k127_5324510_7 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 539.0
HKD1_k127_5324510_8 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 532.0
HKD1_k127_5324510_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 528.0
HKD1_k127_5334943_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1242.0
HKD1_k127_5334943_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1137.0
HKD1_k127_5334943_10 4Fe-4S dicluster domain - - - 3.262e-197 622.0
HKD1_k127_5334943_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 595.0
HKD1_k127_5334943_12 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 582.0
HKD1_k127_5334943_13 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 571.0
HKD1_k127_5334943_14 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 531.0
HKD1_k127_5334943_15 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 510.0
HKD1_k127_5334943_16 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 453.0
HKD1_k127_5334943_17 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 442.0
HKD1_k127_5334943_18 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 435.0
HKD1_k127_5334943_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 436.0
HKD1_k127_5334943_2 PFAM ABC transporter related K06020 - 3.6.3.25 0.0 1046.0
HKD1_k127_5334943_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 411.0
HKD1_k127_5334943_21 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 417.0
HKD1_k127_5334943_22 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 413.0
HKD1_k127_5334943_23 PFAM alpha beta hydrolase fold K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 407.0
HKD1_k127_5334943_24 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 375.0
HKD1_k127_5334943_25 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 347.0
HKD1_k127_5334943_26 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 331.0
HKD1_k127_5334943_27 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
HKD1_k127_5334943_28 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004161 274.0
HKD1_k127_5334943_29 unfolded protein binding K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002323 268.0
HKD1_k127_5334943_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.399e-314 970.0
HKD1_k127_5334943_30 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000001061 247.0
HKD1_k127_5334943_31 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
HKD1_k127_5334943_32 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000000000000002624 206.0
HKD1_k127_5334943_33 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000001181 217.0
HKD1_k127_5334943_34 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000357 200.0
HKD1_k127_5334943_36 membrane K08995 - - 0.000000000000000000000000000000000000000000005155 169.0
HKD1_k127_5334943_37 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.0000000000000000000000000000000000000001383 160.0
HKD1_k127_5334943_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.062e-304 935.0
HKD1_k127_5334943_40 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000005136 143.0
HKD1_k127_5334943_41 - - - - 0.00000000000000000000000000000008822 132.0
HKD1_k127_5334943_42 - - - - 0.0000000000000000000000000002018 121.0
HKD1_k127_5334943_43 rubredoxin - - - 0.000000000000000000000000001151 113.0
HKD1_k127_5334943_44 Histidine Phosphotransfer domain - - - 0.000000000000004719 79.0
HKD1_k127_5334943_45 Trm112p-like protein K09791 - - 0.0000000000002633 73.0
HKD1_k127_5334943_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.565e-240 754.0
HKD1_k127_5334943_6 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 2.865e-232 722.0
HKD1_k127_5334943_7 Aminotransferase class-V - - - 1.787e-210 657.0
HKD1_k127_5334943_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 1.7e-208 653.0
HKD1_k127_5334943_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 9.594e-202 638.0
HKD1_k127_5471766_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 504.0
HKD1_k127_5471766_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 416.0
HKD1_k127_5471766_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 388.0
HKD1_k127_5471766_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 333.0
HKD1_k127_5471766_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 334.0
HKD1_k127_5471766_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 328.0
HKD1_k127_5471766_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000008794 194.0
HKD1_k127_5471766_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001872 192.0
HKD1_k127_5471766_8 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000000000000000000000000000000000007455 162.0
HKD1_k127_5554608_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1068.0
HKD1_k127_5554608_1 4Fe-4S dicluster domain - - - 0.0 1029.0
HKD1_k127_5554608_10 Methyltransferase type 11 K03892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 473.0
HKD1_k127_5554608_11 ThiF family K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 465.0
HKD1_k127_5554608_12 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 433.0
HKD1_k127_5554608_14 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 261.0
HKD1_k127_5554608_15 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
HKD1_k127_5554608_16 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
HKD1_k127_5554608_17 - - - - 0.00000000000000000000000000000000000364 145.0
HKD1_k127_5554608_18 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000001384 152.0
HKD1_k127_5554608_19 Mo-molybdopterin cofactor metabolic process K03154 - - 0.000000000000000000000000000002643 121.0
HKD1_k127_5554608_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.806e-299 919.0
HKD1_k127_5554608_20 LPP20 lipoprotein - - - 0.00000000000000000000002949 111.0
HKD1_k127_5554608_3 electron transfer flavoprotein, alpha subunit K03522 - - 8.909e-242 751.0
HKD1_k127_5554608_4 PFAM iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 2.786e-232 721.0
HKD1_k127_5554608_5 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 6.821e-203 636.0
HKD1_k127_5554608_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 610.0
HKD1_k127_5554608_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 529.0
HKD1_k127_5554608_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 517.0
HKD1_k127_5554608_9 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 488.0
HKD1_k127_5634953_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 539.0
HKD1_k127_5634953_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 443.0
HKD1_k127_5634953_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000007198 225.0
HKD1_k127_5634953_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000000000001001 133.0
HKD1_k127_5731622_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 426.0
HKD1_k127_5731622_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 399.0
HKD1_k127_575319_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1508.0
HKD1_k127_575319_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 8.623e-212 674.0
HKD1_k127_575319_10 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001909 233.0
HKD1_k127_575319_11 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005159 261.0
HKD1_k127_575319_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001144 224.0
HKD1_k127_575319_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000001219 186.0
HKD1_k127_575319_14 mercury ion transmembrane transporter activity K07089,K07213 - - 0.00000000000000000000000000000000000000000000006363 173.0
HKD1_k127_575319_2 TIGRFAM cytochrome C family protein - - - 3.958e-208 655.0
HKD1_k127_575319_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 602.0
HKD1_k127_575319_5 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
HKD1_k127_575319_6 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 372.0
HKD1_k127_575319_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 320.0
HKD1_k127_575319_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005669 291.0
HKD1_k127_575319_9 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000433 245.0
HKD1_k127_5773321_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3292.0
HKD1_k127_5773321_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1380.0
HKD1_k127_5773321_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 3.897e-239 745.0
HKD1_k127_5773321_11 Fumarase C C-terminus K01744 - 4.3.1.1 5.838e-232 727.0
HKD1_k127_5773321_12 - - - - 6.981e-220 689.0
HKD1_k127_5773321_13 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.544e-214 669.0
HKD1_k127_5773321_14 Pfam:KaiC K08482 - - 4.778e-212 668.0
HKD1_k127_5773321_15 Ferrous iron transport protein B - - - 5.907e-212 666.0
HKD1_k127_5773321_16 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 8.479e-209 652.0
HKD1_k127_5773321_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.113e-200 651.0
HKD1_k127_5773321_18 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 590.0
HKD1_k127_5773321_19 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 554.0
HKD1_k127_5773321_2 Iron hydrogenase small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 0.0 1057.0
HKD1_k127_5773321_20 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 526.0
HKD1_k127_5773321_21 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 508.0
HKD1_k127_5773321_22 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
HKD1_k127_5773321_23 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 490.0
HKD1_k127_5773321_24 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 486.0
HKD1_k127_5773321_25 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 446.0
HKD1_k127_5773321_26 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 428.0
HKD1_k127_5773321_27 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 405.0
HKD1_k127_5773321_28 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 405.0
HKD1_k127_5773321_29 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 407.0
HKD1_k127_5773321_3 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.0 1049.0
HKD1_k127_5773321_30 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 397.0
HKD1_k127_5773321_31 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 380.0
HKD1_k127_5773321_32 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 347.0
HKD1_k127_5773321_33 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 338.0
HKD1_k127_5773321_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 318.0
HKD1_k127_5773321_35 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 301.0
HKD1_k127_5773321_36 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 299.0
HKD1_k127_5773321_37 HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
HKD1_k127_5773321_38 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005054 264.0
HKD1_k127_5773321_39 LysM domain K08307,K12204,K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009466 263.0
HKD1_k127_5773321_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 7.5e-322 995.0
HKD1_k127_5773321_40 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006775 235.0
HKD1_k127_5773321_41 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.000000000000000000000000000000000000000000000000000000000000002285 219.0
HKD1_k127_5773321_42 PFAM Transcriptional regulator, histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000005013 238.0
HKD1_k127_5773321_44 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002 198.0
HKD1_k127_5773321_45 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001338 185.0
HKD1_k127_5773321_46 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000000000003146 175.0
HKD1_k127_5773321_47 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000008154 172.0
HKD1_k127_5773321_48 4Fe-4S dicluster domain K14091 - - 0.0000000000000000000000000000000000000000001329 162.0
HKD1_k127_5773321_49 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000006428 157.0
HKD1_k127_5773321_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.66e-317 987.0
HKD1_k127_5773321_50 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000000001785 133.0
HKD1_k127_5773321_51 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000000506 124.0
HKD1_k127_5773321_53 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000001144 124.0
HKD1_k127_5773321_54 - - - - 0.000000005111 62.0
HKD1_k127_5773321_56 Histidine kinase K02482 - 2.7.13.3 0.00002222 56.0
HKD1_k127_5773321_6 PFAM Aldehyde dehydrogenase K00131 - 1.2.1.9 1.283e-301 930.0
HKD1_k127_5773321_7 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 3.362e-287 885.0
HKD1_k127_5773321_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.663e-272 839.0
HKD1_k127_5773321_9 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 1.957e-258 805.0
HKD1_k127_578670_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0 1072.0
HKD1_k127_578670_1 SMART Elongator protein 3 MiaB NifB - - - 1.552e-232 726.0
HKD1_k127_578670_2 Putative metallopeptidase domain - - - 3.963e-202 635.0
HKD1_k127_578670_3 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 602.0
HKD1_k127_578670_5 4Fe-4S dicluster domain - - - 0.000000000003735 66.0
HKD1_k127_5867291_0 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 0.0 1007.0
HKD1_k127_5867291_1 PFAM regulatory protein TetR K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
HKD1_k127_5867291_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000004247 192.0
HKD1_k127_5948389_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1560.0
HKD1_k127_5948389_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 1.152e-232 722.0
HKD1_k127_5948389_10 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000000000003599 183.0
HKD1_k127_5948389_11 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000008304 156.0
HKD1_k127_5948389_12 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000000000006972 121.0
HKD1_k127_5948389_2 PFAM type II secretion system protein E K02669 - - 8.66e-216 673.0
HKD1_k127_5948389_3 Sensor histidine kinase, PAS and GAF domain-containing - - - 4.852e-205 647.0
HKD1_k127_5948389_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 7.014e-199 622.0
HKD1_k127_5948389_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 557.0
HKD1_k127_5948389_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 541.0
HKD1_k127_5948389_7 Motility response receiver histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 538.0
HKD1_k127_5948389_8 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 424.0
HKD1_k127_5948389_9 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000001197 197.0
HKD1_k127_595320_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.331e-263 818.0
HKD1_k127_595320_1 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 574.0
HKD1_k127_595320_10 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000009065 189.0
HKD1_k127_595320_11 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000002385 182.0
HKD1_k127_595320_12 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000004299 164.0
HKD1_k127_595320_13 - - - - 0.0000000000000000000000000000000000000000004877 160.0
HKD1_k127_595320_14 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000003896 158.0
HKD1_k127_595320_15 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000001262 130.0
HKD1_k127_595320_16 - - - - 0.000000000000000000000000000006516 120.0
HKD1_k127_595320_17 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.000000000000000000000000001391 120.0
HKD1_k127_595320_2 2 heme-binding sites K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 527.0
HKD1_k127_595320_20 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000002765 97.0
HKD1_k127_595320_21 response regulator, receiver K03413 - - 0.00000000000000001751 87.0
HKD1_k127_595320_22 Neprosin - - - 0.00000000000155 69.0
HKD1_k127_595320_23 Prolyl oligopeptidase family - - - 0.0000000008535 70.0
HKD1_k127_595320_25 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000579 59.0
HKD1_k127_595320_26 Cysteine-rich domain - - - 0.0002645 47.0
HKD1_k127_595320_3 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 495.0
HKD1_k127_595320_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 347.0
HKD1_k127_595320_5 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 325.0
HKD1_k127_595320_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 287.0
HKD1_k127_595320_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
HKD1_k127_595320_8 Protein of unknown function (DUF1456) - - - 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
HKD1_k127_595320_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000003478 224.0
HKD1_k127_6008480_0 Ompa motb domain protein - - - 0.0 2447.0
HKD1_k127_6008480_1 Aminotransferase class-V K04487 - 2.8.1.7 0.0 1809.0
HKD1_k127_6008480_10 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 5.061e-268 829.0
HKD1_k127_6008480_100 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000000000000000002704 126.0
HKD1_k127_6008480_104 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000001438 107.0
HKD1_k127_6008480_105 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000004487 107.0
HKD1_k127_6008480_108 response regulator - - - 0.0000000000000000000007647 106.0
HKD1_k127_6008480_109 nuclease activity K06218 - - 0.00000000000000000001024 94.0
HKD1_k127_6008480_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.379e-267 824.0
HKD1_k127_6008480_112 Protein of unknown function (DUF2971) - - - 0.000000000000002171 87.0
HKD1_k127_6008480_115 fibronectin type III domain protein - - - 0.000000001077 60.0
HKD1_k127_6008480_117 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000004088 55.0
HKD1_k127_6008480_119 Transcriptional regulator K07726 - - 0.00003934 46.0
HKD1_k127_6008480_12 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.063e-263 822.0
HKD1_k127_6008480_120 alpha/beta hydrolase fold - - - 0.0001011 44.0
HKD1_k127_6008480_13 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 1.045e-262 830.0
HKD1_k127_6008480_14 Belongs to the thiolase family K00626 - 2.3.1.9 3.064e-257 801.0
HKD1_k127_6008480_15 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 1.062e-252 782.0
HKD1_k127_6008480_16 Domain of unknown function (DUF4070) - - - 2.08e-251 785.0
HKD1_k127_6008480_17 Peptidase U62 modulator of DNA gyrase K03568 - - 1.311e-248 772.0
HKD1_k127_6008480_18 SMART Elongator protein 3 MiaB NifB - - - 9.099e-243 756.0
HKD1_k127_6008480_19 Tfp pilus assembly protein FimV - - - 6.094e-227 712.0
HKD1_k127_6008480_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 0.0 1519.0
HKD1_k127_6008480_20 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 4.013e-224 698.0
HKD1_k127_6008480_21 PFAM peptidase U32 K08303 - - 9.009e-210 662.0
HKD1_k127_6008480_22 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.456e-208 659.0
HKD1_k127_6008480_23 MoeA domain protein domain I and II K03750 - 2.10.1.1 5.558e-207 658.0
HKD1_k127_6008480_24 Peptidase family U32 - - - 3.323e-205 649.0
HKD1_k127_6008480_25 PFAM peptidase M16 domain protein - - - 6.477e-204 643.0
HKD1_k127_6008480_26 Protein conserved in bacteria - - - 9.861e-200 634.0
HKD1_k127_6008480_27 Possible lysine decarboxylase K06966 - 3.2.2.10 1.098e-197 619.0
HKD1_k127_6008480_28 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 591.0
HKD1_k127_6008480_29 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 589.0
HKD1_k127_6008480_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1468.0
HKD1_k127_6008480_30 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 592.0
HKD1_k127_6008480_31 HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 569.0
HKD1_k127_6008480_32 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 563.0
HKD1_k127_6008480_33 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 575.0
HKD1_k127_6008480_34 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 561.0
HKD1_k127_6008480_35 PFAM Peptidase C13 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 563.0
HKD1_k127_6008480_36 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 557.0
HKD1_k127_6008480_37 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 562.0
HKD1_k127_6008480_38 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 538.0
HKD1_k127_6008480_39 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 542.0
HKD1_k127_6008480_4 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1414.0
HKD1_k127_6008480_40 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 540.0
HKD1_k127_6008480_41 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 540.0
HKD1_k127_6008480_42 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 552.0
HKD1_k127_6008480_43 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 523.0
HKD1_k127_6008480_44 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 509.0
HKD1_k127_6008480_45 Pfam:DUF422 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 484.0
HKD1_k127_6008480_46 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 481.0
HKD1_k127_6008480_47 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 465.0
HKD1_k127_6008480_48 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 461.0
HKD1_k127_6008480_49 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 462.0
HKD1_k127_6008480_5 GMC oxidoreductase - - - 0.0 1030.0
HKD1_k127_6008480_50 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 458.0
HKD1_k127_6008480_51 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 453.0
HKD1_k127_6008480_52 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 447.0
HKD1_k127_6008480_53 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 455.0
HKD1_k127_6008480_54 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 453.0
HKD1_k127_6008480_55 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 434.0
HKD1_k127_6008480_56 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
HKD1_k127_6008480_57 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 424.0
HKD1_k127_6008480_58 Biotin-lipoyl like K19595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 409.0
HKD1_k127_6008480_59 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 399.0
HKD1_k127_6008480_6 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.0 1022.0
HKD1_k127_6008480_60 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 365.0
HKD1_k127_6008480_61 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 361.0
HKD1_k127_6008480_62 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
HKD1_k127_6008480_63 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 318.0
HKD1_k127_6008480_64 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 316.0
HKD1_k127_6008480_65 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HKD1_k127_6008480_66 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 309.0
HKD1_k127_6008480_67 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 309.0
HKD1_k127_6008480_68 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 302.0
HKD1_k127_6008480_69 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 304.0
HKD1_k127_6008480_7 ABC transporter K06158 - - 3.46e-321 987.0
HKD1_k127_6008480_70 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 313.0
HKD1_k127_6008480_71 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
HKD1_k127_6008480_72 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 282.0
HKD1_k127_6008480_73 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001401 280.0
HKD1_k127_6008480_74 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000466 270.0
HKD1_k127_6008480_75 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
HKD1_k127_6008480_76 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001801 251.0
HKD1_k127_6008480_77 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
HKD1_k127_6008480_78 DNA-binding transcription factor activity K06075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000568 240.0
HKD1_k127_6008480_79 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001117 226.0
HKD1_k127_6008480_8 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.631e-298 919.0
HKD1_k127_6008480_82 Outer membrane protein beta-barrel domain K07275 - - 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
HKD1_k127_6008480_83 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000007707 217.0
HKD1_k127_6008480_84 - - - - 0.0000000000000000000000000000000000000000000000000000000000087 209.0
HKD1_k127_6008480_85 PFAM CYTH domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000004117 205.0
HKD1_k127_6008480_86 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000000000000000000000000000000000000000054 199.0
HKD1_k127_6008480_87 SMART helix-turn-helix domain protein K18831 - - 0.00000000000000000000000000000000000000000000000000002684 190.0
HKD1_k127_6008480_88 Nucleotidyltransferase substrate binding protein like - - - 0.0000000000000000000000000000000000000000000000000122 188.0
HKD1_k127_6008480_89 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000002771 183.0
HKD1_k127_6008480_9 histidine kinase HAMP region domain protein K03406 - - 4.75e-283 881.0
HKD1_k127_6008480_90 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000007177 178.0
HKD1_k127_6008480_91 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000166 173.0
HKD1_k127_6008480_92 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000000001134 163.0
HKD1_k127_6008480_93 Transposase IS200 like - - - 0.000000000000000000000000000000000000003412 158.0
HKD1_k127_6008480_94 electron transfer activity K05337 - - 0.00000000000000000000000000000000000001374 144.0
HKD1_k127_6008480_95 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000001295 140.0
HKD1_k127_6008480_96 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000000001412 138.0
HKD1_k127_6008480_98 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000000006295 130.0
HKD1_k127_6008480_99 Cytochrome c K08906,K12263 - - 0.000000000000000000000000000000006012 132.0
HKD1_k127_6099711_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 3.025e-302 940.0
HKD1_k127_6099711_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 322.0
HKD1_k127_6099711_2 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000003507 56.0
HKD1_k127_6122374_0 MMPL family K07003 - - 0.0 1309.0
HKD1_k127_6122374_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.0 1240.0
HKD1_k127_6122374_11 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 630.0
HKD1_k127_6122374_12 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 569.0
HKD1_k127_6122374_13 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 562.0
HKD1_k127_6122374_14 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 552.0
HKD1_k127_6122374_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 558.0
HKD1_k127_6122374_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 513.0
HKD1_k127_6122374_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 514.0
HKD1_k127_6122374_18 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 479.0
HKD1_k127_6122374_19 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
HKD1_k127_6122374_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1077.0
HKD1_k127_6122374_20 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 347.0
HKD1_k127_6122374_21 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 320.0
HKD1_k127_6122374_22 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 317.0
HKD1_k127_6122374_23 rRNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 308.0
HKD1_k127_6122374_24 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001588 268.0
HKD1_k127_6122374_26 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000003429 232.0
HKD1_k127_6122374_27 PFAM NLP P60 protein K19223 - - 0.00000000000000000000000000000000000000000000000000000000000000001273 233.0
HKD1_k127_6122374_28 hmm pf00545 - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD1_k127_6122374_29 - - - - 0.000000000000000000000000000000000000000000000000000002857 192.0
HKD1_k127_6122374_3 histidine kinase HAMP region domain protein - - - 0.0 1045.0
HKD1_k127_6122374_30 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000004298 188.0
HKD1_k127_6122374_31 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000001452 162.0
HKD1_k127_6122374_32 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000008422 154.0
HKD1_k127_6122374_33 Barstar (barnase inhibitor) K03623 - - 0.0000000000000000000000000000000001542 134.0
HKD1_k127_6122374_36 Protein of unknown function (DUF2905) - - - 0.000000000000000000000000000007233 119.0
HKD1_k127_6122374_37 Helix-turn-helix XRE-family like proteins K15773 - - 0.0000000000000000000000000002408 115.0
HKD1_k127_6122374_38 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000002359 113.0
HKD1_k127_6122374_39 PilZ domain - - - 0.00000000000000000000001502 106.0
HKD1_k127_6122374_4 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.238e-284 897.0
HKD1_k127_6122374_40 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000002715 99.0
HKD1_k127_6122374_41 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000001558 93.0
HKD1_k127_6122374_42 - - - - 0.0000000002362 70.0
HKD1_k127_6122374_43 - - - - 0.000004824 53.0
HKD1_k127_6122374_45 COG0457 FOG TPR repeat - - - 0.0006734 51.0
HKD1_k127_6122374_5 denitrification pathway - - - 5.276e-233 734.0
HKD1_k127_6122374_6 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.723e-214 666.0
HKD1_k127_6122374_7 Pfam:HipA_N K07154 - 2.7.11.1 1.404e-207 652.0
HKD1_k127_6122374_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 7.643e-207 646.0
HKD1_k127_6122374_9 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 9.123e-195 612.0
HKD1_k127_6131812_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1955.0
HKD1_k127_6131812_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 467.0
HKD1_k127_6131812_2 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 416.0
HKD1_k127_6174962_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2151.0
HKD1_k127_6174962_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1751.0
HKD1_k127_6174962_10 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 6.317e-253 788.0
HKD1_k127_6174962_11 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.197e-233 729.0
HKD1_k127_6174962_12 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 8.399e-222 691.0
HKD1_k127_6174962_13 DNA-binding transcription factor activity K02274 - 1.9.3.1 3.589e-215 682.0
HKD1_k127_6174962_14 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 1.922e-213 671.0
HKD1_k127_6174962_15 PFAM Type II secretion system protein E K02669 - - 1.072e-210 657.0
HKD1_k127_6174962_16 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 599.0
HKD1_k127_6174962_17 Nucleotide cyclase, HAMP and GGDEF-related domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 569.0
HKD1_k127_6174962_18 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 560.0
HKD1_k127_6174962_19 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 471.0
HKD1_k127_6174962_2 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1366.0
HKD1_k127_6174962_20 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 391.0
HKD1_k127_6174962_21 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 391.0
HKD1_k127_6174962_22 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 370.0
HKD1_k127_6174962_23 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 367.0
HKD1_k127_6174962_24 Predicted methyltransferase regulatory domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 345.0
HKD1_k127_6174962_25 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 325.0
HKD1_k127_6174962_26 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 303.0
HKD1_k127_6174962_27 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 314.0
HKD1_k127_6174962_28 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 304.0
HKD1_k127_6174962_29 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 282.0
HKD1_k127_6174962_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1250.0
HKD1_k127_6174962_30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
HKD1_k127_6174962_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HKD1_k127_6174962_32 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 280.0
HKD1_k127_6174962_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002126 273.0
HKD1_k127_6174962_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003217 247.0
HKD1_k127_6174962_36 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
HKD1_k127_6174962_37 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000004889 199.0
HKD1_k127_6174962_38 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000024 188.0
HKD1_k127_6174962_39 Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000001051 183.0
HKD1_k127_6174962_4 Cytochrome c3 - - - 0.0 1124.0
HKD1_k127_6174962_40 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000001432 166.0
HKD1_k127_6174962_42 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000001646 175.0
HKD1_k127_6174962_43 peptidoglycan binding - - - 0.0000000000000000000000000000000000000004271 156.0
HKD1_k127_6174962_44 GGDEF domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000005388 154.0
HKD1_k127_6174962_47 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000000003131 131.0
HKD1_k127_6174962_48 cell envelope organization K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000007921 124.0
HKD1_k127_6174962_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1061.0
HKD1_k127_6174962_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1007.0
HKD1_k127_6174962_7 radical SAM domain protein - - - 4.336e-272 855.0
HKD1_k127_6174962_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.323e-267 830.0
HKD1_k127_6174962_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.209e-264 824.0
HKD1_k127_6237963_0 SMART Elongator protein 3 MiaB NifB - - - 1.349e-275 852.0
HKD1_k127_6237963_1 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 3.677e-214 672.0
HKD1_k127_6237963_10 - - - - 0.0000000000000000000000000000001068 129.0
HKD1_k127_6237963_11 Phosphopantetheine attachment site K02078 - - 0.000000000000000000002741 96.0
HKD1_k127_6237963_12 lipid A biosynthesis acyltransferase - - - 0.00000001487 56.0
HKD1_k127_6237963_2 SMART Elongator protein 3 MiaB NifB - - - 3.744e-204 644.0
HKD1_k127_6237963_3 PFAM Beta-ketoacyl synthase K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 430.0
HKD1_k127_6237963_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 421.0
HKD1_k127_6237963_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 347.0
HKD1_k127_6237963_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
HKD1_k127_6237963_7 PFAM Lipid A 3-O-deacylase-related - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
HKD1_k127_6237963_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000211 221.0
HKD1_k127_6237963_9 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000002997 133.0
HKD1_k127_6278522_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0 1080.0
HKD1_k127_6278522_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 543.0
HKD1_k127_6278522_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 451.0
HKD1_k127_6278522_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 281.0
HKD1_k127_6278522_4 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000001243 233.0
HKD1_k127_6419913_0 TIGRFAM conserved repeat domain - - - 0.0 1694.0
HKD1_k127_6419913_1 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0 1469.0
HKD1_k127_6419913_10 Amino acid permease K03294,K14052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 479.0
HKD1_k127_6419913_11 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 377.0
HKD1_k127_6419913_12 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 362.0
HKD1_k127_6419913_13 Shikimate quinate 5-dehydrogenase family protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 339.0
HKD1_k127_6419913_14 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 334.0
HKD1_k127_6419913_15 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 322.0
HKD1_k127_6419913_16 LrgB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 296.0
HKD1_k127_6419913_17 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 294.0
HKD1_k127_6419913_18 PFAM RNA polymerase sigma factor 54, interaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 331.0
HKD1_k127_6419913_19 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 271.0
HKD1_k127_6419913_2 Histidine kinase - - - 0.0 1026.0
HKD1_k127_6419913_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008137 248.0
HKD1_k127_6419913_21 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006125 253.0
HKD1_k127_6419913_22 Pyridoxamine 5'-phosphate oxidase K07006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000256 201.0
HKD1_k127_6419913_23 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000001439 162.0
HKD1_k127_6419913_26 LrgA family K06518 - - 0.000000000000000000000000000000000009509 141.0
HKD1_k127_6419913_27 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000007936 145.0
HKD1_k127_6419913_28 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000001193 96.0
HKD1_k127_6419913_29 ThiS family - - - 0.0000000000000009668 79.0
HKD1_k127_6419913_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.007e-257 859.0
HKD1_k127_6419913_31 - - - - 0.0000000000002478 79.0
HKD1_k127_6419913_32 fibronectin type III domain protein - - - 0.00000006489 53.0
HKD1_k127_6419913_4 HisKA, HATPase_c - - - 1.051e-247 784.0
HKD1_k127_6419913_5 PFAM Aldehyde ferredoxin oxidoreductase - - - 4.153e-219 694.0
HKD1_k127_6419913_6 Belongs to the UbiD family K03182 - 4.1.1.98 1.806e-202 638.0
HKD1_k127_6419913_7 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 4.453e-197 627.0
HKD1_k127_6419913_8 Aminotransferase class-III K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 575.0
HKD1_k127_6419913_9 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 475.0
HKD1_k127_6421150_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 2.992e-201 631.0
HKD1_k127_6421150_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 467.0
HKD1_k127_6421150_2 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 444.0
HKD1_k127_6421150_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 287.0
HKD1_k127_6421150_4 PFAM ROSMUCR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 282.0
HKD1_k127_6421150_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000000000000716 134.0
HKD1_k127_6421150_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0001545 47.0
HKD1_k127_6421150_8 amine dehydrogenase activity - - - 0.0002933 53.0
HKD1_k127_6441173_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1105.0
HKD1_k127_6441173_1 Protein of unknown function, DUF255 K06888 - - 0.0 1039.0
HKD1_k127_6441173_10 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 501.0
HKD1_k127_6441173_11 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K20276 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 496.0
HKD1_k127_6441173_12 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 489.0
HKD1_k127_6441173_13 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 473.0
HKD1_k127_6441173_14 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 462.0
HKD1_k127_6441173_15 UDP-N-acetylglucosamine 2-epimerase K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 456.0
HKD1_k127_6441173_16 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
HKD1_k127_6441173_17 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 432.0
HKD1_k127_6441173_18 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
HKD1_k127_6441173_19 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 423.0
HKD1_k127_6441173_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.168e-313 970.0
HKD1_k127_6441173_20 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 391.0
HKD1_k127_6441173_21 cellulose binding K01183,K01233,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.132,3.2.1.14,3.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 402.0
HKD1_k127_6441173_22 cyclic nucleotide binding K10914,K21562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 375.0
HKD1_k127_6441173_23 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
HKD1_k127_6441173_24 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 352.0
HKD1_k127_6441173_25 3' exoribonuclease, RNase T-like K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
HKD1_k127_6441173_26 PFAM Polysaccharide export protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001081 280.0
HKD1_k127_6441173_27 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004863 263.0
HKD1_k127_6441173_28 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004252 260.0
HKD1_k127_6441173_29 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
HKD1_k127_6441173_3 PFAM oxidoreductase - - - 4.877e-263 828.0
HKD1_k127_6441173_30 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
HKD1_k127_6441173_31 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000000000000009579 194.0
HKD1_k127_6441173_32 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000008774 190.0
HKD1_k127_6441173_33 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001124 191.0
HKD1_k127_6441173_34 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000001487 159.0
HKD1_k127_6441173_37 TadE-like protein - - - 0.00002396 52.0
HKD1_k127_6441173_4 PFAM type II secretion system protein E K02283,K03609 - - 3.844e-228 712.0
HKD1_k127_6441173_5 Pilus formation protein N terminal region K02280 - - 3.454e-199 629.0
HKD1_k127_6441173_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 560.0
HKD1_k127_6441173_7 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 554.0
HKD1_k127_6441173_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 550.0
HKD1_k127_6441173_9 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 525.0
HKD1_k127_6587589_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1740.0
HKD1_k127_6587589_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1369.0
HKD1_k127_6587589_10 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 4.973e-291 906.0
HKD1_k127_6587589_11 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 2.692e-285 882.0
HKD1_k127_6587589_12 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 1.456e-254 790.0
HKD1_k127_6587589_13 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 3.588e-254 791.0
HKD1_k127_6587589_14 Seven times multi-haem cytochrome CxxCH - - - 4.098e-230 718.0
HKD1_k127_6587589_15 Polysulphide reductase, NrfD - - - 3.909e-227 714.0
HKD1_k127_6587589_16 Putative exonuclease, RdgC K03554 - - 1.914e-226 706.0
HKD1_k127_6587589_17 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 4.89e-225 704.0
HKD1_k127_6587589_18 histidine kinase HAMP region domain protein - - - 1.573e-219 713.0
HKD1_k127_6587589_19 MacB-like periplasmic core domain K02004 - - 8.731e-211 659.0
HKD1_k127_6587589_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1302.0
HKD1_k127_6587589_20 MacB-like periplasmic core domain K02004 - - 1.763e-208 652.0
HKD1_k127_6587589_21 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 7.245e-206 652.0
HKD1_k127_6587589_22 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 603.0
HKD1_k127_6587589_23 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 572.0
HKD1_k127_6587589_24 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 571.0
HKD1_k127_6587589_25 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 538.0
HKD1_k127_6587589_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 543.0
HKD1_k127_6587589_27 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 535.0
HKD1_k127_6587589_28 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
HKD1_k127_6587589_29 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 531.0
HKD1_k127_6587589_3 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.0 1178.0
HKD1_k127_6587589_30 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 530.0
HKD1_k127_6587589_31 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 524.0
HKD1_k127_6587589_32 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 519.0
HKD1_k127_6587589_33 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 516.0
HKD1_k127_6587589_34 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 499.0
HKD1_k127_6587589_35 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 483.0
HKD1_k127_6587589_36 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 482.0
HKD1_k127_6587589_37 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 477.0
HKD1_k127_6587589_38 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
HKD1_k127_6587589_39 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 462.0
HKD1_k127_6587589_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1094.0
HKD1_k127_6587589_40 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 461.0
HKD1_k127_6587589_41 YicC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 440.0
HKD1_k127_6587589_42 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 433.0
HKD1_k127_6587589_43 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
HKD1_k127_6587589_44 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 424.0
HKD1_k127_6587589_45 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
HKD1_k127_6587589_46 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 393.0
HKD1_k127_6587589_47 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 390.0
HKD1_k127_6587589_48 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 369.0
HKD1_k127_6587589_49 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 360.0
HKD1_k127_6587589_5 Histidine kinase A domain protein - - - 0.0 1084.0
HKD1_k127_6587589_50 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 358.0
HKD1_k127_6587589_51 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 353.0
HKD1_k127_6587589_52 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 355.0
HKD1_k127_6587589_53 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 342.0
HKD1_k127_6587589_54 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 359.0
HKD1_k127_6587589_56 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
HKD1_k127_6587589_57 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 335.0
HKD1_k127_6587589_58 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HKD1_k127_6587589_59 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 306.0
HKD1_k127_6587589_6 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1052.0
HKD1_k127_6587589_60 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 279.0
HKD1_k127_6587589_61 response regulator K01719,K22010 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 274.0
HKD1_k127_6587589_62 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001873 291.0
HKD1_k127_6587589_63 CHAD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004591 254.0
HKD1_k127_6587589_64 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000002627 238.0
HKD1_k127_6587589_65 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005644 226.0
HKD1_k127_6587589_66 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000007073 227.0
HKD1_k127_6587589_67 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000004072 201.0
HKD1_k127_6587589_68 Peptidase C10 family - - - 0.000000000000000000000000000000000000000000000000000001657 222.0
HKD1_k127_6587589_69 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000003459 179.0
HKD1_k127_6587589_7 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.53e-322 995.0
HKD1_k127_6587589_70 - - - - 0.00000000000000000000000000000000000000000166 159.0
HKD1_k127_6587589_71 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000182 139.0
HKD1_k127_6587589_72 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000006514 133.0
HKD1_k127_6587589_73 - - - - 0.00000000000000000000000000000000006777 150.0
HKD1_k127_6587589_74 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000002045 134.0
HKD1_k127_6587589_75 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000002136 130.0
HKD1_k127_6587589_76 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000008373 121.0
HKD1_k127_6587589_77 Peptidase family M28 K19702 - 3.4.11.24 0.0000000000000000000000006912 124.0
HKD1_k127_6587589_78 PFAM SMP-30 Gluconolaconase K01219 - 3.2.1.81 0.000000000000004203 91.0
HKD1_k127_6587589_79 domain protein K20276 - - 0.00000000000002875 89.0
HKD1_k127_6587589_8 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.713e-320 983.0
HKD1_k127_6587589_83 PhoD-like phosphatase K14274,K14645,K20276 - - 0.00000000294 72.0
HKD1_k127_6587589_85 PFAM Metal-dependent hydrolase HDOD - - - 0.000003426 52.0
HKD1_k127_6587589_9 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 4.487e-297 923.0
HKD1_k127_6660497_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0 1011.0
HKD1_k127_6660497_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 3.424e-230 719.0
HKD1_k127_6660497_10 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 458.0
HKD1_k127_6660497_11 response regulator K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 447.0
HKD1_k127_6660497_12 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 358.0
HKD1_k127_6660497_13 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007992 275.0
HKD1_k127_6660497_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000001004 184.0
HKD1_k127_6660497_15 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000000000000000000000002822 169.0
HKD1_k127_6660497_16 Protein of unknown function (DUF507) - - - 0.00000000000000000000000000000000003453 140.0
HKD1_k127_6660497_17 manually curated - - - 0.000000000000000000000000000001235 123.0
HKD1_k127_6660497_19 - - - - 0.00000000005621 65.0
HKD1_k127_6660497_2 3'-5' exonuclease K03684 - 3.1.13.5 2.171e-210 659.0
HKD1_k127_6660497_20 PFAM GGDEF domain containing protein - - - 0.00002046 53.0
HKD1_k127_6660497_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 2.277e-200 626.0
HKD1_k127_6660497_4 deoxyhypusine monooxygenase activity - - - 7.493e-197 629.0
HKD1_k127_6660497_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 8.339e-197 616.0
HKD1_k127_6660497_6 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 3.673e-195 612.0
HKD1_k127_6660497_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 507.0
HKD1_k127_6660497_8 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 497.0
HKD1_k127_6660497_9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD1_k127_6693424_0 malic protein domain protein K00029 - 1.1.1.40 0.0 1269.0
HKD1_k127_6693424_1 Conserved carboxylase domain K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 0.0 1164.0
HKD1_k127_6693424_2 PFAM carboxyl transferase K01615 - 4.1.1.70 0.0 1118.0
HKD1_k127_6693424_3 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 1.294e-235 731.0
HKD1_k127_6693424_4 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
HKD1_k127_6693424_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000002547 187.0
HKD1_k127_6693424_6 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000002028 101.0
HKD1_k127_6705227_0 PFAM alpha amylase catalytic region K05343 - 3.2.1.1,5.4.99.16 0.0 1794.0
HKD1_k127_6705227_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1454.0
HKD1_k127_6705227_10 radical SAM domain protein K18563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 540.0
HKD1_k127_6705227_11 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 516.0
HKD1_k127_6705227_12 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 515.0
HKD1_k127_6705227_13 Ku70/Ku80 beta-barrel domain K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 438.0
HKD1_k127_6705227_14 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 436.0
HKD1_k127_6705227_15 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 425.0
HKD1_k127_6705227_16 lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HKD1_k127_6705227_17 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 362.0
HKD1_k127_6705227_18 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
HKD1_k127_6705227_19 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 345.0
HKD1_k127_6705227_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1353.0
HKD1_k127_6705227_20 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 323.0
HKD1_k127_6705227_21 Biogenesis protein K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HKD1_k127_6705227_22 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000003306 262.0
HKD1_k127_6705227_23 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001558 256.0
HKD1_k127_6705227_24 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
HKD1_k127_6705227_26 - - - - 0.00000000000000000000000004622 109.0
HKD1_k127_6705227_27 - - - - 0.0000000000000000000101 92.0
HKD1_k127_6705227_28 UPF0391 membrane protein - - - 0.000000000000000006096 84.0
HKD1_k127_6705227_3 DNA ligase K01971 - 6.5.1.1 0.0 1246.0
HKD1_k127_6705227_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1008.0
HKD1_k127_6705227_5 glycoside hydrolase, family 13 domain protein K01236 - 3.2.1.141 7.344e-306 947.0
HKD1_k127_6705227_6 Domain of Unknown Function (DUF748) - - - 8.259e-258 803.0
HKD1_k127_6705227_7 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 1.045e-217 685.0
HKD1_k127_6705227_8 Belongs to the ompA family K03286 - - 8.347e-195 617.0
HKD1_k127_6705227_9 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 562.0
HKD1_k127_6811852_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0 1611.0
HKD1_k127_6811852_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1069.0
HKD1_k127_6811852_10 Alcohol dehydrogenase GroES-associated K00148 - 1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 507.0
HKD1_k127_6811852_11 LysR substrate binding domain K02521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 474.0
HKD1_k127_6811852_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 483.0
HKD1_k127_6811852_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 476.0
HKD1_k127_6811852_14 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 445.0
HKD1_k127_6811852_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 431.0
HKD1_k127_6811852_16 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 435.0
HKD1_k127_6811852_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 424.0
HKD1_k127_6811852_18 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 404.0
HKD1_k127_6811852_19 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 392.0
HKD1_k127_6811852_2 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0 1023.0
HKD1_k127_6811852_20 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 381.0
HKD1_k127_6811852_21 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 365.0
HKD1_k127_6811852_22 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 362.0
HKD1_k127_6811852_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 362.0
HKD1_k127_6811852_24 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 344.0
HKD1_k127_6811852_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
HKD1_k127_6811852_26 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 309.0
HKD1_k127_6811852_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 301.0
HKD1_k127_6811852_28 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 291.0
HKD1_k127_6811852_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006154 278.0
HKD1_k127_6811852_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 4.035e-298 917.0
HKD1_k127_6811852_30 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007463 256.0
HKD1_k127_6811852_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008714 230.0
HKD1_k127_6811852_32 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008803 229.0
HKD1_k127_6811852_33 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003746 184.0
HKD1_k127_6811852_34 PFAM Cache, type 2 - - - 0.00000000000000000000000000000000000006205 148.0
HKD1_k127_6811852_37 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000000001575 120.0
HKD1_k127_6811852_38 Transglycosylase associated protein - - - 0.00000000000000000000000000002133 119.0
HKD1_k127_6811852_39 PFAM YcfA family protein - - - 0.0000000000000000000000000000272 117.0
HKD1_k127_6811852_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.038e-223 695.0
HKD1_k127_6811852_40 Hep Hag repeat protein - - - 0.000000000000000000000000001409 127.0
HKD1_k127_6811852_41 oxygen carrier activity K03406,K07216 - - 0.00000000000000000005391 94.0
HKD1_k127_6811852_42 PFAM Fibronectin, type III domain - - - 0.00000000000002015 84.0
HKD1_k127_6811852_46 - - - - 0.00000003593 61.0
HKD1_k127_6811852_47 Domain of unknown function (DUF1738) - - - 0.0000001197 55.0
HKD1_k127_6811852_48 fibronectin type III domain protein - - - 0.0000001632 53.0
HKD1_k127_6811852_49 Chromosomal replication initiator, DnaA K07491 - - 0.000000389 53.0
HKD1_k127_6811852_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 5.197e-214 668.0
HKD1_k127_6811852_50 Domain of unknown function (DUF1738) - - - 0.000001828 51.0
HKD1_k127_6811852_51 fibronectin type III domain protein - - - 0.00000288 49.0
HKD1_k127_6811852_52 Transposase IS200 like - - - 0.00008354 49.0
HKD1_k127_6811852_6 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 8.073e-199 628.0
HKD1_k127_6811852_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 593.0
HKD1_k127_6811852_8 PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 591.0
HKD1_k127_6811852_9 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 550.0
HKD1_k127_6838199_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 556.0
HKD1_k127_6838199_1 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000218 257.0
HKD1_k127_7118521_0 Histidine kinase HAMP - - - 3.353e-307 953.0
HKD1_k127_7118521_1 B12 binding domain - - - 1.419e-251 782.0
HKD1_k127_7118521_10 Psort location CytoplasmicMembrane, score K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 291.0
HKD1_k127_7118521_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
HKD1_k127_7118521_13 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HKD1_k127_7118521_14 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000004021 190.0
HKD1_k127_7118521_15 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000094 193.0
HKD1_k127_7118521_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000004201 178.0
HKD1_k127_7118521_17 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000001011 165.0
HKD1_k127_7118521_18 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000000000000000000007236 132.0
HKD1_k127_7118521_19 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.0000000000000000000000000000006039 125.0
HKD1_k127_7118521_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 6.124e-246 768.0
HKD1_k127_7118521_20 methylamine metabolic process K15977 - - 0.00000000000000000000001528 104.0
HKD1_k127_7118521_21 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000005896 98.0
HKD1_k127_7118521_22 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000578 54.0
HKD1_k127_7118521_3 PFAM Extracellular ligand-binding receptor K01999 - - 1.018e-216 679.0
HKD1_k127_7118521_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.696e-208 661.0
HKD1_k127_7118521_5 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 8.339e-200 627.0
HKD1_k127_7118521_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 507.0
HKD1_k127_7118521_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 500.0
HKD1_k127_7118521_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 459.0
HKD1_k127_7118521_9 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 455.0
HKD1_k127_7145615_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1929.0
HKD1_k127_7145615_1 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 2.142e-278 859.0
HKD1_k127_7145615_2 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 4.628e-257 799.0
HKD1_k127_7145615_3 PFAM major facilitator superfamily MFS_1 K02575 - - 3.158e-250 778.0
HKD1_k127_7145615_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 358.0
HKD1_k127_7145615_5 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 319.0
HKD1_k127_7145615_6 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 299.0
HKD1_k127_7145615_7 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000006127 206.0
HKD1_k127_7145615_8 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000003914 196.0
HKD1_k127_7145615_9 DinB superfamily - - - 0.00000000000000000000000005882 114.0
HKD1_k127_7187787_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1823.0
HKD1_k127_7187787_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1500.0
HKD1_k127_7187787_10 Thiamine biosynthesis protein ThiC K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 1.608e-268 829.0
HKD1_k127_7187787_100 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000002381 200.0
HKD1_k127_7187787_102 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000000000000000000001462 175.0
HKD1_k127_7187787_103 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000001638 182.0
HKD1_k127_7187787_104 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000002008 170.0
HKD1_k127_7187787_105 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000000000000000000000006227 160.0
HKD1_k127_7187787_107 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000008659 157.0
HKD1_k127_7187787_108 Chitinase class I K03791 - - 0.0000000000000000000000000000000000001533 154.0
HKD1_k127_7187787_109 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000002759 140.0
HKD1_k127_7187787_11 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 2.773e-268 828.0
HKD1_k127_7187787_110 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000000003779 141.0
HKD1_k127_7187787_111 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000004257 150.0
HKD1_k127_7187787_112 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000005281 141.0
HKD1_k127_7187787_114 - - - - 0.00000000000000000000000001846 110.0
HKD1_k127_7187787_116 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000001152 96.0
HKD1_k127_7187787_117 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000001088 102.0
HKD1_k127_7187787_118 - K02009 - - 0.0000000000000000308 84.0
HKD1_k127_7187787_12 The M ring may be actively involved in energy transduction K02409 - - 1.073e-264 822.0
HKD1_k127_7187787_120 - - - - 0.0000000000001561 83.0
HKD1_k127_7187787_121 PFAM Phosphoribosyltransferase - - - 0.000000000008746 65.0
HKD1_k127_7187787_122 Protein of unknown function (DUF2845) - - - 0.00000000001873 69.0
HKD1_k127_7187787_124 Flagellar assembly protein FliH K02411 - - 0.00000003027 64.0
HKD1_k127_7187787_125 Chitinase class I K03791 - - 0.00000004043 65.0
HKD1_k127_7187787_127 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000001793 57.0
HKD1_k127_7187787_128 - - - - 0.000001603 57.0
HKD1_k127_7187787_13 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 1.84e-257 797.0
HKD1_k127_7187787_14 protein trimerization K06894,K07114 - - 1.888e-256 809.0
HKD1_k127_7187787_15 response regulator - - - 1.154e-253 788.0
HKD1_k127_7187787_16 Chemotaxis sensory transducer K03406 - - 9.67e-239 760.0
HKD1_k127_7187787_17 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.239e-238 741.0
HKD1_k127_7187787_18 histidine kinase, HAMP - - - 4.144e-236 737.0
HKD1_k127_7187787_19 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 3.819e-230 732.0
HKD1_k127_7187787_2 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.0 1384.0
HKD1_k127_7187787_20 Aromatic amino acid lyase K01745 - 4.3.1.3 1.007e-228 723.0
HKD1_k127_7187787_21 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 5.061e-224 701.0
HKD1_k127_7187787_22 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.657e-210 664.0
HKD1_k127_7187787_23 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 4.766e-198 621.0
HKD1_k127_7187787_24 Pyridine nucleotide-disulphide oxidoreductase K00383 - 1.8.1.7 2.987e-194 614.0
HKD1_k127_7187787_25 flagellar motor switch protein FliG K02410 - - 7.968e-194 606.0
HKD1_k127_7187787_26 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 598.0
HKD1_k127_7187787_27 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 609.0
HKD1_k127_7187787_28 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 583.0
HKD1_k127_7187787_29 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 578.0
HKD1_k127_7187787_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1120.0
HKD1_k127_7187787_30 flagellar motor switch protein FliM K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 565.0
HKD1_k127_7187787_31 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 574.0
HKD1_k127_7187787_32 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 557.0
HKD1_k127_7187787_33 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 559.0
HKD1_k127_7187787_34 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 547.0
HKD1_k127_7187787_35 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 541.0
HKD1_k127_7187787_36 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 535.0
HKD1_k127_7187787_37 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 514.0
HKD1_k127_7187787_38 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 497.0
HKD1_k127_7187787_39 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 496.0
HKD1_k127_7187787_4 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.0 1043.0
HKD1_k127_7187787_40 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 491.0
HKD1_k127_7187787_41 GGDEF domain K01768,K02482,K02658,K03413,K07315 - 2.7.13.3,3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 487.0
HKD1_k127_7187787_42 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 478.0
HKD1_k127_7187787_43 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 466.0
HKD1_k127_7187787_44 beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 460.0
HKD1_k127_7187787_45 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 466.0
HKD1_k127_7187787_46 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 453.0
HKD1_k127_7187787_47 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 434.0
HKD1_k127_7187787_48 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
HKD1_k127_7187787_49 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 402.0
HKD1_k127_7187787_5 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0 1034.0
HKD1_k127_7187787_50 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 419.0
HKD1_k127_7187787_51 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 378.0
HKD1_k127_7187787_52 flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HKD1_k127_7187787_53 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 371.0
HKD1_k127_7187787_54 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 375.0
HKD1_k127_7187787_55 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 377.0
HKD1_k127_7187787_56 Nucleoside-specific channel-forming protein, Tsx - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 368.0
HKD1_k127_7187787_57 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
HKD1_k127_7187787_58 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 361.0
HKD1_k127_7187787_59 Belongs to the arginase family K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 364.0
HKD1_k127_7187787_6 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.897e-304 940.0
HKD1_k127_7187787_60 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 372.0
HKD1_k127_7187787_61 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 357.0
HKD1_k127_7187787_62 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
HKD1_k127_7187787_63 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 362.0
HKD1_k127_7187787_64 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 349.0
HKD1_k127_7187787_65 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 342.0
HKD1_k127_7187787_66 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
HKD1_k127_7187787_67 alpha-ribazole phosphatase activity K02226,K22305,K22306 - 3.1.3.3,3.1.3.73,3.1.3.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 325.0
HKD1_k127_7187787_68 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 314.0
HKD1_k127_7187787_69 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 301.0
HKD1_k127_7187787_7 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.877e-291 898.0
HKD1_k127_7187787_70 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 326.0
HKD1_k127_7187787_71 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 301.0
HKD1_k127_7187787_72 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 287.0
HKD1_k127_7187787_73 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 280.0
HKD1_k127_7187787_74 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001727 278.0
HKD1_k127_7187787_75 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001198 280.0
HKD1_k127_7187787_76 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001064 271.0
HKD1_k127_7187787_77 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005585 289.0
HKD1_k127_7187787_78 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000138 254.0
HKD1_k127_7187787_79 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003184 258.0
HKD1_k127_7187787_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.345e-279 864.0
HKD1_k127_7187787_80 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000007301 266.0
HKD1_k127_7187787_81 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
HKD1_k127_7187787_82 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HKD1_k127_7187787_83 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000004241 226.0
HKD1_k127_7187787_84 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000000009908 213.0
HKD1_k127_7187787_85 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
HKD1_k127_7187787_86 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000003467 214.0
HKD1_k127_7187787_87 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000000000001719 202.0
HKD1_k127_7187787_88 Putative flagellar - - - 0.000000000000000000000000000000000000000000000000000000002025 201.0
HKD1_k127_7187787_89 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000000000000000008186 204.0
HKD1_k127_7187787_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.667e-273 846.0
HKD1_k127_7187787_90 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000001529 217.0
HKD1_k127_7187787_91 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
HKD1_k127_7187787_92 flagellar K02418 - - 0.00000000000000000000000000000000000000000000000000000005647 203.0
HKD1_k127_7187787_93 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
HKD1_k127_7187787_94 PFAM flagellar hook-length control K02414 - - 0.0000000000000000000000000000000000000000000000000000001129 219.0
HKD1_k127_7187787_95 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000002063 194.0
HKD1_k127_7187787_96 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000000000008563 189.0
HKD1_k127_7187787_97 PFAM MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000001298 190.0
HKD1_k127_7187787_98 Flagellar motor switch protein FliN K02417 - - 0.000000000000000000000000000000000000000000000000005065 181.0
HKD1_k127_7187787_99 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000002662 182.0
HKD1_k127_7224477_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1138.0
HKD1_k127_7224477_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1021.0
HKD1_k127_7224477_10 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 598.0
HKD1_k127_7224477_11 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 580.0
HKD1_k127_7224477_12 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 572.0
HKD1_k127_7224477_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 530.0
HKD1_k127_7224477_14 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 519.0
HKD1_k127_7224477_15 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 523.0
HKD1_k127_7224477_16 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 486.0
HKD1_k127_7224477_17 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 484.0
HKD1_k127_7224477_18 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 473.0
HKD1_k127_7224477_19 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 473.0
HKD1_k127_7224477_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.5e-293 899.0
HKD1_k127_7224477_20 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 446.0
HKD1_k127_7224477_21 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
HKD1_k127_7224477_22 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 439.0
HKD1_k127_7224477_23 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 434.0
HKD1_k127_7224477_24 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 415.0
HKD1_k127_7224477_25 (EAL) domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 396.0
HKD1_k127_7224477_26 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 430.0
HKD1_k127_7224477_27 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 394.0
HKD1_k127_7224477_28 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 362.0
HKD1_k127_7224477_29 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 357.0
HKD1_k127_7224477_3 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 1.77e-254 801.0
HKD1_k127_7224477_30 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
HKD1_k127_7224477_31 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 349.0
HKD1_k127_7224477_32 response regulator K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 342.0
HKD1_k127_7224477_33 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 328.0
HKD1_k127_7224477_34 Dehydrogenase E1 component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 312.0
HKD1_k127_7224477_35 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 297.0
HKD1_k127_7224477_36 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
HKD1_k127_7224477_37 sigma factor antagonist activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001988 288.0
HKD1_k127_7224477_38 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001651 269.0
HKD1_k127_7224477_39 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004206 268.0
HKD1_k127_7224477_4 FAD dependent oxidoreductase K07137 - - 5.735e-252 785.0
HKD1_k127_7224477_40 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003034 257.0
HKD1_k127_7224477_41 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002722 255.0
HKD1_k127_7224477_42 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006123 243.0
HKD1_k127_7224477_43 transposition, DNA-mediated - - - 0.000000000000000000000000000000000000000000000000000000000000287 219.0
HKD1_k127_7224477_44 phosphorelay signal transduction system K03413 - - 0.000000000000000000000000000000000000000000000000000000005045 201.0
HKD1_k127_7224477_45 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000001641 197.0
HKD1_k127_7224477_46 Membrane - - - 0.0000000000000000000000000000000000000000000000001344 182.0
HKD1_k127_7224477_48 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001735 170.0
HKD1_k127_7224477_49 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000006457 166.0
HKD1_k127_7224477_5 histidine kinase - - - 1.739e-222 693.0
HKD1_k127_7224477_50 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000003336 169.0
HKD1_k127_7224477_51 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000000000000000000008456 151.0
HKD1_k127_7224477_53 antisigma factor binding - - - 0.000000000000000000000000001587 117.0
HKD1_k127_7224477_55 Prolipoprotein diacylglyceryl transferase - - - 0.00000000000000001384 87.0
HKD1_k127_7224477_56 ISXO2-like transposase domain - - - 0.00000000000006507 74.0
HKD1_k127_7224477_57 Involved in the tonB-independent uptake of proteins - - - 0.000000001055 73.0
HKD1_k127_7224477_59 Collagen triple helix repeat (20 copies) - - - 0.00006302 56.0
HKD1_k127_7224477_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.219e-201 633.0
HKD1_k127_7224477_61 Zonadhesin - GO:0000003,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0009566,GO:0009987,GO:0009988,GO:0016020,GO:0019953,GO:0022414,GO:0022610,GO:0035036,GO:0043900,GO:0044464,GO:0044703,GO:0050789,GO:0050794,GO:0050840,GO:0051704,GO:0065007,GO:0071944,GO:0080154,GO:0098609,GO:2000241,GO:2000359 - 0.0002075 48.0
HKD1_k127_7224477_7 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 1.18e-198 623.0
HKD1_k127_7224477_8 peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 5.459e-198 623.0
HKD1_k127_7224477_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 3.278e-196 617.0
HKD1_k127_7233527_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0 1253.0
HKD1_k127_7233527_1 FtsX-like permease family K02004 - - 0.0 1119.0
HKD1_k127_7233527_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.745e-269 833.0
HKD1_k127_7233527_11 Iron-sulfur cluster-binding domain - - - 5.131e-254 788.0
HKD1_k127_7233527_12 Radical SAM domain protein K03424 - - 5.14e-254 789.0
HKD1_k127_7233527_13 Sensor diguanylate cyclase, GAF domain-containing - - - 8.246e-254 802.0
HKD1_k127_7233527_14 Na+/Pi-cotransporter K03324 - - 2.681e-244 766.0
HKD1_k127_7233527_15 B12 binding domain - - - 4.661e-235 731.0
HKD1_k127_7233527_16 Major facilitator superfamily MFS_1 - - - 4.46e-220 687.0
HKD1_k127_7233527_17 B12 binding domain K04034 - 1.21.98.3 6.326e-216 685.0
HKD1_k127_7233527_18 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 3.885e-206 649.0
HKD1_k127_7233527_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 5.194e-198 627.0
HKD1_k127_7233527_2 type IV pilus assembly PilZ - - - 0.0 1039.0
HKD1_k127_7233527_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 599.0
HKD1_k127_7233527_21 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 592.0
HKD1_k127_7233527_22 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 570.0
HKD1_k127_7233527_23 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 540.0
HKD1_k127_7233527_24 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 529.0
HKD1_k127_7233527_25 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 516.0
HKD1_k127_7233527_26 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 480.0
HKD1_k127_7233527_27 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 455.0
HKD1_k127_7233527_28 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 429.0
HKD1_k127_7233527_29 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 430.0
HKD1_k127_7233527_3 Domain of Unknown Function (DUF748) - - - 0.0 1038.0
HKD1_k127_7233527_30 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HKD1_k127_7233527_31 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 386.0
HKD1_k127_7233527_32 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 376.0
HKD1_k127_7233527_33 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 377.0
HKD1_k127_7233527_34 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 370.0
HKD1_k127_7233527_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 374.0
HKD1_k127_7233527_36 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 364.0
HKD1_k127_7233527_37 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 351.0
HKD1_k127_7233527_38 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD1_k127_7233527_39 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 326.0
HKD1_k127_7233527_4 metal-dependent phosphohydrolase HD region - - - 5.7e-322 996.0
HKD1_k127_7233527_40 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 326.0
HKD1_k127_7233527_41 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
HKD1_k127_7233527_42 Outer membrane lipoprotein LolB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 259.0
HKD1_k127_7233527_43 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 254.0
HKD1_k127_7233527_44 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003475 255.0
HKD1_k127_7233527_45 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004111 249.0
HKD1_k127_7233527_46 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000008865 224.0
HKD1_k127_7233527_47 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
HKD1_k127_7233527_48 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000000000000000000043 170.0
HKD1_k127_7233527_49 - - - - 0.0000000000000000000000000000000000000000000005166 177.0
HKD1_k127_7233527_5 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 4.039e-319 978.0
HKD1_k127_7233527_50 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000009711 147.0
HKD1_k127_7233527_52 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000716 134.0
HKD1_k127_7233527_55 Belongs to the NifD NifK NifE NifN family K02587 - - 0.0000000001177 62.0
HKD1_k127_7233527_57 FabA-like domain K02372 - 4.2.1.59 0.00000001469 62.0
HKD1_k127_7233527_58 - - - - 0.0000001262 57.0
HKD1_k127_7233527_6 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 5.926e-318 974.0
HKD1_k127_7233527_7 Protein export membrane protein K07003 - - 1.848e-316 989.0
HKD1_k127_7233527_8 Histidine kinase - - - 5.307e-275 862.0
HKD1_k127_7233527_9 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 4.84e-270 833.0
HKD1_k127_7279755_0 AMP-binding enzyme C-terminal domain K12507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 571.0
HKD1_k127_7279755_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 564.0
HKD1_k127_7279755_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
HKD1_k127_7279755_12 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000001261 65.0
HKD1_k127_7279755_2 -ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 466.0
HKD1_k127_7279755_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 393.0
HKD1_k127_7279755_4 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 325.0
HKD1_k127_7279755_5 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 312.0
HKD1_k127_7279755_6 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 308.0
HKD1_k127_7279755_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 298.0
HKD1_k127_7279755_8 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009043 299.0
HKD1_k127_7279755_9 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003822 242.0
HKD1_k127_7283345_0 Metal-dependent phosphohydrolase K07037 - - 0.0 1262.0
HKD1_k127_7283345_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1045.0
HKD1_k127_7283345_10 Protein of unknown function (DUF1015) - - - 2.9e-233 725.0
HKD1_k127_7283345_11 Protein of unknown function (DUF512) - - - 1.226e-226 707.0
HKD1_k127_7283345_12 PFAM RNA binding S1 domain protein K02945 - - 2.11e-212 664.0
HKD1_k127_7283345_13 dioxygenase K00464 - 1.13.11.75 8.358e-211 666.0
HKD1_k127_7283345_14 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.699e-205 640.0
HKD1_k127_7283345_15 belongs to the CobB CobQ family K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 597.0
HKD1_k127_7283345_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 477.0
HKD1_k127_7283345_17 S4 RNA-binding domain K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 468.0
HKD1_k127_7283345_18 PFAM CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 476.0
HKD1_k127_7283345_19 PFAM import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 444.0
HKD1_k127_7283345_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.66e-304 948.0
HKD1_k127_7283345_20 PFAM NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD1_k127_7283345_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 454.0
HKD1_k127_7283345_22 CRISPR-associated endoribonuclease Cas6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 398.0
HKD1_k127_7283345_24 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 356.0
HKD1_k127_7283345_25 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
HKD1_k127_7283345_26 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 349.0
HKD1_k127_7283345_27 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 341.0
HKD1_k127_7283345_28 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 335.0
HKD1_k127_7283345_29 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 318.0
HKD1_k127_7283345_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 1.084e-299 923.0
HKD1_k127_7283345_30 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000056 261.0
HKD1_k127_7283345_31 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008676 254.0
HKD1_k127_7283345_32 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003619 248.0
HKD1_k127_7283345_33 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000134 247.0
HKD1_k127_7283345_34 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 235.0
HKD1_k127_7283345_35 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000000000000000000000000008797 203.0
HKD1_k127_7283345_36 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000008846 153.0
HKD1_k127_7283345_37 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000000000008634 140.0
HKD1_k127_7283345_38 Protein conserved in bacteria K09954 - - 0.000000000000000000000000000000000138 133.0
HKD1_k127_7283345_39 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000003975 120.0
HKD1_k127_7283345_4 Belongs to the RtcB family K14415 - 6.5.1.3 1.184e-292 900.0
HKD1_k127_7283345_40 PFAM Type IV pilus assembly PilZ - - - 0.000000000000000000000000004251 118.0
HKD1_k127_7283345_5 PFAM Cys Met metabolism K01740 - 2.5.1.49 4.903e-271 837.0
HKD1_k127_7283345_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.166e-264 815.0
HKD1_k127_7283345_7 Response regulator, receiver K13246 - 3.1.4.52 2.991e-263 817.0
HKD1_k127_7283345_8 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 1.11e-256 794.0
HKD1_k127_7283345_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 8.538e-243 759.0
HKD1_k127_7289308_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 7.038e-285 889.0
HKD1_k127_7289308_1 histidine kinase HAMP region domain protein K03406 - - 3.182e-272 847.0
HKD1_k127_7289308_10 Outer membrane protein beta-barrel domain K07275 - - 0.000000000000000000000000000000002701 131.0
HKD1_k127_7289308_11 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000001229 129.0
HKD1_k127_7289308_2 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 599.0
HKD1_k127_7289308_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 585.0
HKD1_k127_7289308_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
HKD1_k127_7289308_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 335.0
HKD1_k127_7289308_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002154 250.0
HKD1_k127_7289308_7 protein histidine kinase activity K07315,K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000004637 249.0
HKD1_k127_7289308_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000009133 208.0
HKD1_k127_7295750_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.0 1314.0
HKD1_k127_7295750_1 cluster binding protein - - - 0.0 1239.0
HKD1_k127_7295750_10 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 5.694e-235 736.0
HKD1_k127_7295750_11 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.295e-221 689.0
HKD1_k127_7295750_12 Type VI secretion system, TssF K11896 - - 3.236e-218 693.0
HKD1_k127_7295750_13 Phage late control gene D protein (GPD) K11904 - - 1.072e-209 668.0
HKD1_k127_7295750_14 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.819e-203 634.0
HKD1_k127_7295750_15 metal-dependent phosphohydrolase, HD sub domain K07814 - - 4.378e-202 638.0
HKD1_k127_7295750_16 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 595.0
HKD1_k127_7295750_17 Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 559.0
HKD1_k127_7295750_18 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 538.0
HKD1_k127_7295750_19 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 498.0
HKD1_k127_7295750_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1191.0
HKD1_k127_7295750_20 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 428.0
HKD1_k127_7295750_21 Regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 426.0
HKD1_k127_7295750_22 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 412.0
HKD1_k127_7295750_23 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HKD1_k127_7295750_24 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 318.0
HKD1_k127_7295750_25 type VI secretion protein K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000195 290.0
HKD1_k127_7295750_26 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006384 266.0
HKD1_k127_7295750_27 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009828 255.0
HKD1_k127_7295750_28 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000263 246.0
HKD1_k127_7295750_29 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002202 243.0
HKD1_k127_7295750_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1139.0
HKD1_k127_7295750_30 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
HKD1_k127_7295750_31 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000005879 177.0
HKD1_k127_7295750_32 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000001519 166.0
HKD1_k127_7295750_33 - - - - 0.0000000000000000000000000000000000006464 147.0
HKD1_k127_7295750_34 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000000000000007736 136.0
HKD1_k127_7295750_35 TM2 domain - - - 0.0000000000000000000000000000000003951 138.0
HKD1_k127_7295750_36 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000002262 132.0
HKD1_k127_7295750_39 - - - - 0.000000004265 57.0
HKD1_k127_7295750_4 TIGRFAM L-lactate transport K03303 - - 0.0 1084.0
HKD1_k127_7295750_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1049.0
HKD1_k127_7295750_6 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 3.824e-268 828.0
HKD1_k127_7295750_7 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 2.021e-252 780.0
HKD1_k127_7295750_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 1.765e-241 756.0
HKD1_k127_7295750_9 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 5.574e-241 748.0
HKD1_k127_7302812_0 histidine kinase HAMP region domain protein K03406 - - 0.0 1557.0
HKD1_k127_7302812_1 elongation factor Tu domain 2 protein K02355 - - 0.0 1291.0
HKD1_k127_7302812_10 PFAM transport-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 460.0
HKD1_k127_7302812_11 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 456.0
HKD1_k127_7302812_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 451.0
HKD1_k127_7302812_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 386.0
HKD1_k127_7302812_14 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 359.0
HKD1_k127_7302812_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 357.0
HKD1_k127_7302812_16 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 347.0
HKD1_k127_7302812_17 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
HKD1_k127_7302812_18 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
HKD1_k127_7302812_19 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002768 289.0
HKD1_k127_7302812_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.981e-254 796.0
HKD1_k127_7302812_20 COG0671 Membrane-associated phospholipid phosphatase - GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
HKD1_k127_7302812_24 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000119 117.0
HKD1_k127_7302812_26 - - - - 0.00000000007689 69.0
HKD1_k127_7302812_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 3.336e-253 790.0
HKD1_k127_7302812_4 12 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 561.0
HKD1_k127_7302812_5 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 529.0
HKD1_k127_7302812_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 513.0
HKD1_k127_7302812_7 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 501.0
HKD1_k127_7302812_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 483.0
HKD1_k127_7302812_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 476.0
HKD1_k127_7308681_0 Histidine kinase - - - 1.561e-275 863.0
HKD1_k127_7308681_1 response regulator - - - 1.08e-252 788.0
HKD1_k127_7308681_10 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
HKD1_k127_7308681_11 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 319.0
HKD1_k127_7308681_12 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 326.0
HKD1_k127_7308681_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001392 234.0
HKD1_k127_7308681_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000003841 217.0
HKD1_k127_7308681_15 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000001265 175.0
HKD1_k127_7308681_16 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000000000000000000558 165.0
HKD1_k127_7308681_18 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000006875 123.0
HKD1_k127_7308681_19 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000000000002081 131.0
HKD1_k127_7308681_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.034e-229 717.0
HKD1_k127_7308681_20 gluconolactonase activity - - - 0.0000000000000002873 89.0
HKD1_k127_7308681_22 fibronectin type III domain protein - - - 0.0000002439 53.0
HKD1_k127_7308681_3 two component, sigma54 specific, transcriptional regulator, Fis family K10943 - - 6.648e-224 700.0
HKD1_k127_7308681_4 Putative diguanylate phosphodiesterase - - - 4.426e-221 700.0
HKD1_k127_7308681_5 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 506.0
HKD1_k127_7308681_6 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 471.0
HKD1_k127_7308681_7 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 441.0
HKD1_k127_7308681_9 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 342.0
HKD1_k127_7370547_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1020.0
HKD1_k127_7370547_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 8.074e-282 873.0
HKD1_k127_7370547_2 PFAM Class II aldolase K01628 - 4.1.2.17 8.353e-200 627.0
HKD1_k127_7370547_3 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 580.0
HKD1_k127_7370547_4 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 446.0
HKD1_k127_7370547_5 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 449.0
HKD1_k127_7370547_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
HKD1_k127_7623852_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1563.0
HKD1_k127_7623852_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 484.0
HKD1_k127_7623852_10 - - - - 0.000000000000000000001417 95.0
HKD1_k127_7623852_11 denitrification pathway - - - 0.000000000000000000005986 93.0
HKD1_k127_7623852_2 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 407.0
HKD1_k127_7623852_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 364.0
HKD1_k127_7623852_4 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 300.0
HKD1_k127_7623852_5 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HKD1_k127_7623852_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000006526 177.0
HKD1_k127_7623852_7 - - - - 0.0000000000000000000000000000000001116 140.0
HKD1_k127_7623852_8 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000008951 130.0
HKD1_k127_7623852_9 PIN domain - - - 0.0000000000000000000000004339 109.0
HKD1_k127_7871497_0 histidine kinase, dimerisation and phosphoacceptor region - - - 8.464e-217 680.0
HKD1_k127_7871497_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 547.0
HKD1_k127_7871497_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000004996 199.0
HKD1_k127_7871497_11 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000001068 170.0
HKD1_k127_7871497_12 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000001128 152.0
HKD1_k127_7871497_13 ParB-like nuclease domain - - - 0.0000000000000000000000000000000000001337 152.0
HKD1_k127_7871497_14 Protein of unknown function (DUF1566) - - - 0.0000000000000000000517 106.0
HKD1_k127_7871497_15 Protein of unknown function (DUF1566) - - - 0.0000000000000000002058 104.0
HKD1_k127_7871497_16 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000001277 79.0
HKD1_k127_7871497_17 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000002217 78.0
HKD1_k127_7871497_18 Sulfotransferase family - - - 0.000000001352 70.0
HKD1_k127_7871497_19 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - 0.000000003668 62.0
HKD1_k127_7871497_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 531.0
HKD1_k127_7871497_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 453.0
HKD1_k127_7871497_4 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 428.0
HKD1_k127_7871497_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 300.0
HKD1_k127_7871497_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 310.0
HKD1_k127_7871497_8 Glycosyl transferase, family 2 K16648 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003292 263.0
HKD1_k127_7977433_1 SMART Elongator protein 3 MiaB NifB - - - 1.697e-288 893.0
HKD1_k127_7977433_10 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000799 209.0
HKD1_k127_7977433_11 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000002647 178.0
HKD1_k127_7977433_12 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000000000006813 161.0
HKD1_k127_7977433_13 - - - - 0.0000000000000000000000000000000000000001999 151.0
HKD1_k127_7977433_15 cell envelope organization K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000004102 133.0
HKD1_k127_7977433_16 - - - - 0.000000000000000005853 94.0
HKD1_k127_7977433_17 light absorption - - - 0.0000000000002225 74.0
HKD1_k127_7977433_2 PFAM Xanthine uracil vitamin C permease K06901 - - 4.91e-241 749.0
HKD1_k127_7977433_3 AAA domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 458.0
HKD1_k127_7977433_4 Nucleotide cyclase, HAMP and GGDEF-related domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 451.0
HKD1_k127_7977433_5 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
HKD1_k127_7977433_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 386.0
HKD1_k127_7977433_7 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 354.0
HKD1_k127_7977433_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 321.0
HKD1_k127_7977433_9 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000509 270.0
HKD1_k127_80524_0 HELICc2 K03722 - 3.6.4.12 0.0 1452.0
HKD1_k127_80524_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1211.0
HKD1_k127_80524_10 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 1.454e-210 664.0
HKD1_k127_80524_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 1.966e-206 645.0
HKD1_k127_80524_12 Flagellar basal body rod protein K02396 - - 6.904e-196 621.0
HKD1_k127_80524_13 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 599.0
HKD1_k127_80524_14 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
HKD1_k127_80524_15 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 576.0
HKD1_k127_80524_16 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 565.0
HKD1_k127_80524_17 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 547.0
HKD1_k127_80524_18 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 547.0
HKD1_k127_80524_19 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 537.0
HKD1_k127_80524_2 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1068.0
HKD1_k127_80524_20 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 526.0
HKD1_k127_80524_21 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 528.0
HKD1_k127_80524_22 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 484.0
HKD1_k127_80524_23 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 479.0
HKD1_k127_80524_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 477.0
HKD1_k127_80524_25 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 468.0
HKD1_k127_80524_26 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 456.0
HKD1_k127_80524_27 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 453.0
HKD1_k127_80524_28 Belongs to the flagella basal body rod proteins family K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 448.0
HKD1_k127_80524_29 bacterial-type flagellum-dependent cell motility K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 432.0
HKD1_k127_80524_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 7.446e-315 970.0
HKD1_k127_80524_30 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 420.0
HKD1_k127_80524_31 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 415.0
HKD1_k127_80524_32 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 407.0
HKD1_k127_80524_33 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 401.0
HKD1_k127_80524_34 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 389.0
HKD1_k127_80524_35 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 387.0
HKD1_k127_80524_36 PFAM Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HKD1_k127_80524_37 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 368.0
HKD1_k127_80524_38 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 364.0
HKD1_k127_80524_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 369.0
HKD1_k127_80524_4 PFAM magnesium chelatase ChlI subunit K07391 - - 1.421e-300 925.0
HKD1_k127_80524_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 357.0
HKD1_k127_80524_41 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 357.0
HKD1_k127_80524_42 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 343.0
HKD1_k127_80524_43 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 355.0
HKD1_k127_80524_44 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 341.0
HKD1_k127_80524_45 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 335.0
HKD1_k127_80524_46 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 323.0
HKD1_k127_80524_47 NosL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 309.0
HKD1_k127_80524_48 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 310.0
HKD1_k127_80524_49 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 303.0
HKD1_k127_80524_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.789e-264 817.0
HKD1_k127_80524_50 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 301.0
HKD1_k127_80524_51 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 292.0
HKD1_k127_80524_52 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001682 285.0
HKD1_k127_80524_53 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 291.0
HKD1_k127_80524_54 Guanylyl transferase CofC like K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
HKD1_k127_80524_55 PFAM Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009151 254.0
HKD1_k127_80524_56 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
HKD1_k127_80524_57 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000006663 223.0
HKD1_k127_80524_58 - - - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
HKD1_k127_80524_59 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000002766 208.0
HKD1_k127_80524_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 6.961e-249 772.0
HKD1_k127_80524_60 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000001799 195.0
HKD1_k127_80524_61 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000000000000000000001786 191.0
HKD1_k127_80524_64 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000003232 183.0
HKD1_k127_80524_65 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000002224 166.0
HKD1_k127_80524_66 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.0000000000000000000000000000000000000005112 152.0
HKD1_k127_80524_67 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000001032 143.0
HKD1_k127_80524_68 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000000000000000000000000277 135.0
HKD1_k127_80524_69 PFAM Flagellar protein K02395 - - 0.0000000000000000000000000000001245 127.0
HKD1_k127_80524_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.295e-242 757.0
HKD1_k127_80524_70 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000004202 124.0
HKD1_k127_80524_71 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000002425 119.0
HKD1_k127_80524_72 Transposase IS200 like K07491 - - 0.0000000000000000000000007886 105.0
HKD1_k127_80524_74 Transposase K07491 - - 0.000000000000000000001022 97.0
HKD1_k127_80524_76 Transposase IS200 like - - - 0.00000000000000000001188 100.0
HKD1_k127_80524_77 Tellurite resistance protein TehB - - - 0.0000000000004666 72.0
HKD1_k127_80524_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 2.745e-228 710.0
HKD1_k127_80524_9 Sigma-70 factor, region 1.1 K03086 - - 2.22e-217 689.0
HKD1_k127_990310_0 NUBPL iron-transfer P-loop NTPase - - - 2.665e-251 782.0
HKD1_k127_990310_1 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 378.0
HKD1_k127_990310_2 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000000000000000000000000179 142.0
HKD1_k127_990310_3 S23 ribosomal protein - - - 0.000000000000000000000000000000003534 132.0